CN103585258A - Traditional Chinese medicine composition for treating breast pain - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating breast pain, and relates to the technical field of Chinese herbal medicines. The traditional Chinese medicine composition consists of the following active ingredients by weight: 14-16g of angelica sinensis, 11-13g of ligusticum wallichii, 8-10g of myrrh, 11-13g of trichosanthes peel and 5-7g of liquorice. The traditional Chinese medicine composition meets the traditional Chinese medicine differentiation theory in traditional Chinese medicine selection and matching, is remarkable in treatment effect and free of toxic and side effects, and mainly functions as relieving pain, activating the blood, relaxing grain and promoting the circulation of qi, and the purpose that the traditional Chinese medicines supplement each other in matching is achieved.

Description

A kind of Chinese medicine composition that is used for the treatment of mastalgia

Technical field

The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of Chinese medicine composition that is used for the treatment of mastalgia.

Background technology

Mastalgia, pure breast epithelium hypertrophy disease, is the early lesion of mammary dysplasia.The generation of this disease, development and ovarian endocrine state are closely related.Chinese traditional treatment mastalgia be take conditioning endocrine as main, and logical blood blood stasis dispelling, eliminates old complaint.Chinese traditional treatment mastalgia is effective, and few side effects is painful few.

Summary of the invention

It is a kind of effective that technical problem to be solved by this invention is to provide, the safe and reliable Chinese medicine composition that is used for the treatment of mastalgia.

Technical problem to be solved by this invention realizes by the following technical solutions:

A Chinese medicine composition that is used for the treatment of mastalgia, is comprised of the crude drug of following weight,

Radix Angelicae Sinensis 14-16 gram, Rhizoma Chuanxiong 11-13 gram, Myrrha 8-10 gram, Pericarpium Trichosanthis 11-13 gram, Radix Glycyrrhizae 5-7 gram.

Preferred weight part of each crude drug is:

15 grams of Radix Angelicae Sinensis, 12 grams of Rhizoma Chuanxiongs, 9 grams of Myrrhas, 12 grams of Pericarpium Trichosanthiss, 6 grams, Radix Glycyrrhizae.

The present invention's crude drug used can be bought and obtain from common Chinese shop, and its specification meets national Chinese crude drug standard.

Another object of the present invention is to provide a kind of method of preparing the present composition, comprises the steps,

1) by the described weight of prescription, take each taste crude drug;

2) above-mentioned each taste material medicine is mixed be placed on and in marmite, add water and do not have powder, soak after 30 minutes, with slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction.

1, pharmacology analysis:

Radix Angelicae Sinensis: control menoxenia, amenorrhea stomachache ， mass in the abdomen knot is poly-, metrorrhagia; Headache due to deficiency of blood, dizzy, flaccidity syndrome and arthralgia syndrome; Dryness of the intestine dyschezia is heavy after bloody dysentery; Carbuncle skin ulcer is stolen, injury from falling down.

Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.

Myrrha: cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There are the effects such as promoting blood circulation and stopping pain, detumescence and promoting granulation.

Pericarpium Trichosanthis: moistening the lung and resolving phlegm, promoting the circulation of QI the chest stuffiness relieving.Control phlegm-heat cough, pharyngalgia, chest pain, spits blood, and epistaxis, quenches one's thirst, constipation, carbuncle pyogenic infections from tumour or sore.

Radix Glycyrrhizae: heat-clearing and toxic substances removing, nourishing the lung to arrest cough, coordinating the actions of various ingredients in a prescription.

2, usage and consumption:

The dosage of medicine of the present invention depends on concrete dosage form, and the factor such as age of patient, body weight, health status.Instruction: decoction: once, late one after each meal, 5 days is a course for the treatment of to a pair.

3, the present composition has carried out a large amount of clinical trials of a large amount of animal acute toxicity tests, long-term toxicity test for animals and treatment disease, and the use link that this medicine is dropped into treatment disease provides science and objective foundation.Its test method and result of the test are as follows respectively:

1) decoction of being prepared by the present invention carries out animal acute toxicity test:

Medicine: the present invention's crude drug used is bought and obtained from common Chinese shop, and its specification meets national Chinese crude drug standard.

Experimental animal: white mice, body weight is in 50g left and right, and male and female are selected at random, by market, are bought.

Method and result: get 30 of white mice, hungry about 20 hours, by filling with several times every every day, feed 50ml, feed one week continuously, to observe 10 days, mice is movable normal, and non-toxic reaction, without dead.Show that oral liquid is without acute toxicity, clinical medicine dose safety.

2) decoction of being prepared by the present invention carries out long-term toxicity test for animals:

Experimental animal: rat, body weight is at 120-130g, and male and female are selected at random, by market, are bought.

Method and result: get 20 of rat, be divided into 2 groups, every group 10, wherein the 1st group as administration group, by filling with several times every every day, feed 40-50ml, the 2nd group of normal feeding as a control group, once a day, continuous irrigation is fed 90 days, survey body weight, 24 hours sacrificed by decapitation after last administration, survey blood, routine urinalysis, liver function, renal function, core, the internal organs such as kidney, the variation of tissues observed form, observe the effect of dosage, observe diet, movable variation, experimental results show that administration group and matched group are relatively without significant change, equal non-toxic reaction, a kind of safe drugs.

4, diagnostic criteria

1) clinical diagnosis: > > is diagnostic criteria according to < < People's Republic of China (PRC) Chinese medicine industry standard (disease of tcm Standardization of diagnosis and curative effect).

2) in order to verify clinical efficacy, this prescription is tried out in First People's Hospital, Jieshou City, Anhui Province respectively, chooses at random wherein 50 routine patients.

3) Therapeutic Method: according to drug ratios of the present invention, take raw material (dosage), according to the method for conventionally boiling medicine, obtain medicinal liquid, late one after each meal, taking 5 days is a course for the treatment of.The shortest 1 course for the treatment of, the longest 12 courses for the treatment of.

4) efficacy determination:

Recovery from illness: lump in breast and pain symptom all disappear;

Effective: lump in breast and pain symptom disappear;

Effective: lump in breast dwindles, pain relief

Invalid: cardinal symptom is unchanged or worsen, the change of local disease has the trend of increasing the weight of.

Concrete therapeutic outcome is referring to table 1;

Table 1

Number of cases	Recovery from illness	Effective	Effectively	Invalid	Effective percentage (%)
						50	20	24	5	1	98

5, points for attention:

1. diet should be light, gives up alcohol and pungent, raw and cold, greasy food.

2. child, women breast-feeding their children, elderly and infirm should take under doctor instructs.

3. driver, work high above the ground person are cautious use of.

4. strictly by usage and dosage, take.

5. pair this medicine and ethanol allergy sufferers are forbidden, and allergic constitution person be cautious use of.

6. when this property of drug changes, ban use of.

7. please this medicine is placed on to the place that child can not contact.

8. as use other medicines, using please Ref Dr or pharmacist before this medicine.

The invention has the beneficial effects as follows: the present invention Chinese crude drug select and compatibility on meet Chinese medical discrimination theory, therapeutic effect is remarkable, and has no side effect, mainly take pain relieving, invigorate blood circulation, relaxing muscles and tendons network, circulation of qi promoting be as main, reached complementary object in drug matching.

The specific embodiment

For technological means, creation characteristic that the present invention is realized, reach object and effect is easy to understand, below in conjunction with specific embodiment, further set forth the present invention.

Embodiment 1

By following weight, take each crude drug: 15 grams of Radix Angelicae Sinensis, 12 grams of Rhizoma Chuanxiongs, 9 grams of Myrrhas, 12 grams of Pericarpium Trichosanthiss, 6 grams, Radix Glycyrrhizae;

Above-mentioned each taste material medicine is mixed to be placed in marmite, add water and do not have powder, soak after 30 minutes, with slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction, one pair once, late one after each meal, 5 days courses for the treatment of.

Embodiment 2

By following parts by weight, take each crude drug: 14 grams of Radix Angelicae Sinensis, 11 grams of Rhizoma Chuanxiongs, 8 grams of Myrrhas, 11 grams of Pericarpium Trichosanthiss, 5 grams, Radix Glycyrrhizae;

Above-mentioned each taste material medicine is mixed to be placed in marmite, add water and do not have powder, soak after 30 minutes, with slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction, one pair once, late one after each meal, 5 days courses for the treatment of.

Embodiment 3

By following parts by weight, take each crude drug: 16 grams of Radix Angelicae Sinensis, 13 grams of Rhizoma Chuanxiongs, 10 grams of Myrrhas, 13 grams of Pericarpium Trichosanthiss, 7 grams, Radix Glycyrrhizae;

Above-mentioned each taste material medicine is mixed to be placed in marmite, add water and do not have powder, soak after 30 minutes, with slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction, one pair once, late one after each meal, 5 days courses for the treatment of.

Model case:

Case 1

Song, female, 25 years old, people from Shou County, Liuan City, Anhui Province is unmarried.Patient's readme, bilateral mastalgia, touches with lump with hands, and nipple has a small amount of discharge, and pain is of that month, menoxenia.Take the decoction that the present invention's prescription boils, after the course for the treatment of, lump disappears substantially, painless.After take again two courses for the treatment of and consolidated, follow up a case by regular visits to half a year for recurrence.

Case 2

Enemy so-and-so, female, 45 years old, peasant, west city people from street, Jieshou City, Anhui Province, married.Right breast is pain and lump periodically, after take the present invention's decoction of writing out a prescription, within 5 days, pain symptom disappears, recovery from illness in a week, follows up a case by regular visits to, and does not recur.

Case 3

High so-and-so Jieshou City, ，Nv ，27Sui， Anhui Province village people of Jin stockaded village is unmarried.Left breast swells and ache, and haves a medical check-up and can touch graininess tag, pliable.Take decoction of the present invention, after 1 course for the treatment of, pain disappears, after take continuously again 4 courses for the treatment of, transference cure, recovery from illness.Following up a case by regular visits to 1 year, is recurrence.

Case 4

Turn round and look at so-and-so the Fuyang City people of ，Nv ，32Sui， Anhui Province, married.In mammary gland, lump is nodositas, and pain is pliable unclear with surrounding tissue boundary, can promote.Take Chinese medicine composition provided by the invention, after 1 week, pain disappears, and after 3 weeks, swollen thing diminishes.

More than show and described ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; that in above-described embodiment and description, describes just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.The claimed scope of the present invention is defined by appending claims and equivalent thereof.

Claims (3)

1. a Chinese medicine composition that is used for the treatment of mastalgia, is characterized in that: the crude drug by following weight forms,

Radix Angelicae Sinensis 14-16 gram, Rhizoma Chuanxiong 11-13 gram, Myrrha 8-10 gram, Pericarpium Trichosanthis 11-13 gram, Radix Glycyrrhizae 5-7 gram.

2. a kind of Chinese medicine composition that is used for the treatment of mastalgia according to claim 1, is characterized in that: the crude drug by following weight forms,

15 grams of Radix Angelicae Sinensis, 12 grams of Rhizoma Chuanxiongs, 9 grams of Myrrhas, 12 grams of Pericarpium Trichosanthiss, 6 grams, Radix Glycyrrhizae.

3. a method of preparing Chinese medicine composition described in claim 1 or 2 any one, is characterized in that: comprises the following steps,

1) by the described weight of prescription, take each taste crude drug;

2) above-mentioned each taste material medicine is mixed be placed on and in marmite, add water and do not have powder, soak after 30 minutes, with slow fire boiling, after boiling, renew and decoct 30 minutes, decoct altogether three times, merge three decocting liquids and filter, obtain decoction.