CN102018752A - Chinese medicine preparation used for treating acute mastitis - Google Patents
Chinese medicine preparation used for treating acute mastitis Download PDFInfo
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- CN102018752A CN102018752A CN2010105689578A CN201010568957A CN102018752A CN 102018752 A CN102018752 A CN 102018752A CN 2010105689578 A CN2010105689578 A CN 2010105689578A CN 201010568957 A CN201010568957 A CN 201010568957A CN 102018752 A CN102018752 A CN 102018752A
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Abstract
The invention provides a Chinese medicine preparation used for treating acute mastitis, in particular to a Chinese medicine preparation compatibled from pure Chinese herbal medicines. The Chinese medicine preparation is characterized by being prepared from manis pentadactyla, musk, semen brassicae, radix angelicae pubescentis, liquorice and divaricate saposhnikovia root at certain weight ratio; the Chinese medicine preparation can effectively treat acute mastitis, the clinical curative ratio is 77%, the effective rate is 22%, and the clinical total effective rate is 99%. The Chinese medicine preparation is prepared from pure Chinese herbal medicines and has no toxic or side effect. The Chinese medicine preparation is externally applied, thus being convenient to use.
Description
Technical field
The invention belongs to the field of Chinese medicines, the Chinese medicine preparation of the acute galactophore series disease of treatment that particularly a kind of pure drug matching forms.
Background technology
Acute galactophore series disease mainly shows as acute mastitis, be to invade or directly invade latex dust along lymphatic vessel by staphylococcus aureus, the inflammation that goes upward to glandular lobule and cause, be mainly in the puerpera in 3-4 week in puerperal, also see man and old children, the clinical mastalgia that mainly shows as, local red and swollen, heating, the shiver with cold that continued, the hyperpyrexia pulse is accelerated, side lymphangoncus.Pathological manifestations can form single room or multiloculated abscess for originally presenting cellulitis sample performance after a couple of days, outwards diabrosis of abscess, and deep abscess also can be worn to breast and become retromammary abscess with open texture between the chest muscle, infects when serious, can concurrent sepsis.Western medical treatment is mainly with the antibiotic control infection, and how with penicillin, celpillina I treatment, local inflammation can be covered, and the abscess of secondary needs incision and drainage, and treatment cycle was generally 20-30 days, and patient's misery is bigger.It is acute mastitis that the traditional Chinese medical science is looked acute mammary gland class, how from integral body, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs is stoping development, the anti-inflammatory analgetic aspect obtains certain effect, but from clinical literature in recent years, the understanding to primary disease biases toward dispersing the stagnated live-QI to relieve the stagnation of QI more, lactogenesis eliminating stagnation side medicine oral, lest there being the QI and blood ice crystal to form the fraud that scleroma is not dissipated for a long time, so dare not cross the product with cold and cool detoxifcation, effect is not satisfactory.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation by the external application for curing acute mastitis, main effect is for from outward appearance to inner essence, heat-clearing and toxic substances removing, swollenization silt clearly.
The present invention is achieved in that
The Chinese medicine preparation of treatment acute mastitis is characterized in that raw material composition and the weight proportion of wherein making active ingredient are: Squama Manis 30--60, Moschus 5--10, Semen Sinapis Albae 5--20, Radix Angelicae Pubescentis 20--40, Radix Glycyrrhizae 5-30 and Radix Saposhnikoviae 10--30.
After the present invention adopts technical scheme, have following clinical effectiveness:
1, effectively treats acute mastitis, clinical cure rate 77%, effective percentage 22%, clinical total effective rate 99%.
2, pure Chinese medicine is made, and has no side effect.
3, external application is used, and is easy to use.
Acute mastitis is because of human milk silt, nipple breakage or the infection that staphylococcus aureus invasion lymphatic vessel, latex dust to glandular lobule cause after being chapped from the cold, modern pharmacological research proves, the routed carbuncle of detumescence, the medicine of collateral dredging dissipating blood stasis can suppress to kill staphylococcus aureus, it is active to search wind, and the initiation medicine of chafe then can play the sterilization guiding drug is oozed effect to focus.
Among the present invention:
1, Squama Manis: salty, be slightly cold, poisonous.The routed carbuncle of energy detumescence, it is active to search wind, and the stimulating milk secretion of stimulating the menstrual flow, Compendium of Material Medica are carried and are controlled " galactostasis " " acute mastitis ".
2, Moschus: have ward off dirty, the function of collateral dredging dissipating blood stasis.
3, Semen Sinapis Albae: hot, warm.It is outer as skin irritation initiation medicine that " modern practical Chinese medicine " carries " mashing as mud ".
Above-mentioned three flavors are monarch drug altogether.
4, Radix Saposhnikoviae: Xin Gan, temperature." not Lu " carries and " controls the most difficult closing in person of carbuncle." epidermis healing behind the ruptured abscess is had good effect.
5, Radix Angelicae Pubescentis: Zhang Yuansu work: " the carbuncle deteriorated blood looses." sepsis there are stronger prevention and control action.
6, Radix Glycyrrhizae: lung moistening, detoxifcation, the small piece of land surrounded by water medicine that is in harmonious proportion especially at the compatibility of poisonous Squama Manis cold in nature, change that it is poisonous, use its bitter cold.
Above-mentioned three flavors are ministerial drug
Treatment mechanism of the present invention:
The present invention is based on the cold and cool detoxifcation medicine of appearance application and execute the understanding of the method for controlling, selected person is for detumescence relieves the pain, the carbuncle of bursting of becoming silted up of loosing, draw table saturating in, the combination of the strong compatibility of drugs of holder skin ulcer granulation promoting.In the prescription, the Squama Manis detumescence carbuncle of bursting, it is active to search wind, the stimulating milk secretion of stimulating the menstrual flow, Moschus collateral dredging dissipating blood stasis is equipped with the Semen Sinapis Albae that causes in going into and associates with and be altogether to reach monarch drug and coordinate mutually, from outward appearance to inner essence, strengthens infiltration, kills outer effect of attacking the poison heresy.Radix Saposhnikoviae, Radix Angelicae Pubescentis in the side hold in the palm the effect of skin ulcer granulation promoting fully.Radix Glycyrrhizae then with middle emergency, dissolve the poison of Squama Manis own again when being in harmonious proportion all flavors, be to be ministerial drug, the monarch and his subjects are auxilliary mutually, bring out the best in each other, effect is sensible, prompt speed causes carbuncle, compares with dispersing liver-energy, clearing away stomach-heat, the oral prescription of lactogenesis repercussive, obviously receives the effect of getting twice the result with half the effort.To sum up state, drug regimen of the present invention and using method have by table to the lining, and detoxification is pressed evil, and clearing heat for detumescence is holding up this solid just, the effect of the silt tissue regeneration promoting that looses, and external application is used, and is evident in efficacy.
The specific embodiment
Below in conjunction with embodiment the present invention is elaborated.
Embodiment 1
Extracting liquorice 15g, Radix Saposhnikoviae 20g, Radix Angelicae Pubescentis 30g, decocting are agent, get solution 500ml.Get Squama Manis 50g, Moschus 10g, Semen Sinapis Albae 15g again, grind sieve (280 order) for powder, sneak in the above-mentioned solution, blending forms ointment preparation, and is standby.
During use,, get above-mentioned ointment preparation, evenly be applied to the affected part, cover with the scraps of paper after the sterilization according to patient's inflammation size, each 3-6 hour, the next day once, five times one courses of treatment.Can effectively treat acute galactophore series disease.
Embodiment 2
Extracting liquorice 5g, Radix Saposhnikoviae 30g, Radix Angelicae Pubescentis 20g, decocting are agent, get solution 500ml.Get Squama Manis 60g, Moschus 5g, Semen Sinapis Albae 20g again, grind sieve (280 order) for powder, sneak in the above-mentioned solution, blending forms ointment preparation, and is standby.Using method is the same.
Embodiment 3
Extracting liquorice 30g, Radix Saposhnikoviae 10g, Radix Angelicae Pubescentis 40g, decocting are agent, get solution 500ml.Get Squama Manis 30g, Moschus 10g, Semen Sinapis Albae 5g again, grind sieve (280 order) for powder, sneak in the above-mentioned solution, blending forms ointment preparation, and is standby.Using method is the same.
Embodiment 4
Extracting liquorice 20g, Radix Saposhnikoviae 15g, Radix Angelicae Pubescentis 25g, decocting are agent, get solution 500ml.Get Squama Manis 30g, Moschus 8g, Semen Sinapis Albae 10g again, grind sieve (280 order) for powder, sneak in the above-mentioned solution, blending forms ointment preparation, and is standby.Using method is the same.
Clinical trial
For verifying therapeutic effect of the present invention, the applicant has carried out following clinical experiment in Donga, Shandong Province county institute of traditional Chinese medicine to the present invention in 2005-2009:
1, data and method
1.1 diagnostic criteria
1.1.1 Western medicine diagnose standard
With reference to the People's Health Publisher " 15 " and National planning teaching material " diagnostics " standard, 1. breast red, swollen, painful, often be confined to a certain quadrant of a side breast.2. palpation has the scleroma enclosed mass, companion's shiver with cold, and the heating perspiration waits the whole body poisoning symptom.There is an above-mentioned person can be diagnosed as acute mastitis.
1.1.2 tcm diagnosis standard
With reference to State Administration of Traditional Chinese Medicine＜traditional Chinese medical science disease diagnosis criterion of therapeutical effect in 1999 ".1. locomorphic stage, show as mammary swelling, and it is not smooth that milk is discharged, companion's fever with aversion to cold, and xerostomia hardship, inappetence, body of the tongue are red partially, yellow and thin fur, stringy pulse.2. red and swollen phase: Huan Ru inflammation is red, scorching hot, swelling, and pain is obvious, galactostasis, hyperpyrexia is thirsty, and is vexed easily dry, constipation, red tongue with yellow fur is thick, wiry and frequent pulse.3. stadium suppurations: suffer from newborn redness more very, pain exacerbate be jump painful, the patient fear touch local, dysphoria, high fever does not move back, thirst and liking drink, the deliquescing of lump central authorities has fluctuation and touches a tender spot obviously by it, red tongue, yellow fur is thick, full and rapid pulse.
1.2 physical data
Method:
36 examples are organized in treatment, use this medicine, the next day once, applied 3-6 hour at every turn, five times one courses of treatment, some cases is observed 6 courses of treatment.
Matched group 36 examples are just used the each 1g of oxacillin sodium (celpillina I), 4 intramuscular injection every day or quiet, and abscess forms back otch drain, concurrent mammary fistula after the drain, oral bromocriptine 1.25mg took 7-14 days every day 2 times, stopped secretion to milk.
1.3 efficacy assessment standard
Cure: symptom is all eliminated, and functional rehabilitation is normal, and main physical and chemical index check is normal.
Effectively: symptom is eliminated substantially, and because of otch drain or mammary fistula treatment stopping suckling, main physical and chemical index check is normal.
Invalid: with the treatment before compare, each side does not all have progress.
2, therapeutic outcome contrast (as table 1,2)
Table 1 clinical symptoms, sign and contrast number.
Table 2 Therapeutic Method and effect contrast
From table 1, table 2 as can be seen, treatment group and matched group are compared, on Therapeutic Method and effect marked difference is arranged, illustrate that Chinese medicine preparation of the present invention can effectively avoid I ﹠ D misery and suckling to end, its curative effect is better than the medication of penicillin, oxacillin sodium (celpillina I).
3, conclusion
The present invention is to the cardinal symptom of acute mammary gland class, and sign all has good improvement effect, has avoided incision and drainage to the misery that the patient brings especially, has reached the recovery from illness of big portion, overall effectively curative effect.
Concrete case.
Case 1 Song, woman, 26 years old, people from Donga County, Shandong.Because of left side breast redness in seven days puerperal, pain and with fever, came institute to go to a doctor on the 10th in JIUYUE in 2005, be diagnosed as the acute mastitis initial stage on inspection, do not form abscess as yet, give medicine of the present invention and treat, the next day application six hours, symptom all disappears after ten days, does not influence suckling, pays a return visit and does not have recurrence.
Case 2 Mas, woman, 24 years old, horse people from market town, Qihe County.The right breast of readme fortnight in puerperal is red and swollen, pain and with heating, treat the commentaries on classics of not getting better after three days for quiet in the commune hospital, town, come institute to go to a doctor on April 16th, 2008, being diagnosed as the acute mastitis abscess on inspection forms, giving medicine of the present invention treats, application once a day six hours, the pain heating paresthesia disappears after five days, symptom is eliminated after 15 days, and is normal through the check numeration of leukocyte, and drug withdrawal gives a course of treatment ten medicines of the present invention again to consolidate after three days, follow up a case by regular visits to nothing recurrence, recovery from illness in June, 2008.
Case 3 wars, man, 19 years old, Pingying County hole people from village, rub broken left nipple when readme is had a bath accidentally with the hands, play redness next day, pain, heating, from clothes anti-inflammation analgesic three days in the future the state of an illness do not see gently that heavily the back is outer to be coated with " PIYANPING " a few days and to cause shiver with cold, hyperpyrexia, came institute's prescription on individual diagnosis on March 21st, 2009, as seen ruptured abscess, be diagnosed as the acute mastitis ruptured abscess,, give medicine external application of the present invention because of fearing incision surgery, once a day, application five hours, next day pain relief, after burning moved back on 3rd, use continuously Drug therapy of the present invention after 20 days all diseases all disappear wound healing.Follow up a case by regular visits in June, 2009 and do not have recurrence.
Claims (2)
1. the Chinese medicine preparation of treatment acute mastitis is characterized in that raw material composition and the weight proportion of wherein making active ingredient are: Squama Manis 30--60, Moschus 5--10, Semen Sinapis Albae 5--20, Radix Angelicae Pubescentis 20--40, Radix Glycyrrhizae 5-30 and Radix Saposhnikoviae 10--30.
2. the Chinese medicine preparation of treatment acute mastitis according to claim 1 is characterized in that the weight proportion of described raw material is: Squama Manis 50, Moschus 10, Semen Sinapis Albae 15, Radix Angelicae Pubescentis 30, Radix Glycyrrhizae 15 and Radix Saposhnikoviae 20.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105689578A CN102018752A (en) | 2010-12-02 | 2010-12-02 | Chinese medicine preparation used for treating acute mastitis |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010105689578A CN102018752A (en) | 2010-12-02 | 2010-12-02 | Chinese medicine preparation used for treating acute mastitis |
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| CN102018752A true CN102018752A (en) | 2011-04-20 |
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| CN2010105689578A Pending CN102018752A (en) | 2010-12-02 | 2010-12-02 | Chinese medicine preparation used for treating acute mastitis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302651A (en) * | 2011-08-23 | 2012-01-04 | 张方山 | External application Chinese medicine for treating proliferation of mammary gland |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1089501A (en) * | 1993-08-31 | 1994-07-20 | 乌鹏喜 | Moschus Hippocampus panchrest plaster and preparation method thereof |
| CN101002900A (en) * | 2007-01-05 | 2007-07-25 | 梁进 | Plaster for detumescence and drawing out poison |
-
2010
- 2010-12-02 CN CN2010105689578A patent/CN102018752A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1089501A (en) * | 1993-08-31 | 1994-07-20 | 乌鹏喜 | Moschus Hippocampus panchrest plaster and preparation method thereof |
| CN101002900A (en) * | 2007-01-05 | 2007-07-25 | 梁进 | Plaster for detumescence and drawing out poison |
Non-Patent Citations (1)
| Title |
|---|
| 《上海中医药杂志》 20020615 陈丽云 外用黑膏药的临床研究概况 , 第06期 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302651A (en) * | 2011-08-23 | 2012-01-04 | 张方山 | External application Chinese medicine for treating proliferation of mammary gland |
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Application publication date: 20110420 |