CN107007798A - 用于改善心脑血管循环的药香及其制备方法 - Google Patents
用于改善心脑血管循环的药香及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种用于改善心脑血管循环的药香及其制备方法，所述药香包括桑枝、桂枝、山栀子、大黄、钻地风、干姜、黄芪、紫菀、鸡血藤、高良姜、白芷、川断、川芎、千年健、杜仲、独活、木香、透骨草、木鳖子、乳香、荜拔、降香、没药、榆皮。本发明所述用于改善心脑血管循环的药香，气味芳香，使用时患者从呼吸道闻吸药物气味，直接作用于鼻、支气管及肺部，从而达到疏通血管、疏通经络的功效，可以促进机体血液循环，有利于气血顺畅。
Description
技术领域
本发明涉及中药香的配方和制备工艺领域，具体涉及一种用于改善心脑血管循环的药香及其制备方法。
背景技术
心脑血管疾病是指因血液供应障碍而引起的心脏和脑部疾病的总称。心脑血管疾病具有发病率高、致残率高、死亡率高、复发率高、并发症多的特点，为患者生命安全带来了严重的危害。现实生活中，心脑血管疾病患者的发病大多具有突然性和意外性。因此，做好心脑血管疾病的治疗和预防至关重要。
中华医学对闻吸疗法有不少论述，它通过呼吸道闻吸药味而达到治疗疾病的目的。《内经》云：“肺者，气之本，开窍于鼻。”《疮疡全书》云:“鼻孔为肺之窍，其气上通于脑，下行于肺，”“鼻纳而通六经”，说明气味药从鼻而人，上通于脑，下达于肺，通十二经脉。经现代医学研究发现，闻吸气味药通过嗅觉细胞及嗅觉中枢而发生疗效，这是因为进人鼻腔的气体分子，首先溶于粘液中与鼻纤毛相依感受气体分子，将信号转换成嗅神经电信号，再向嗅中枢传送，不同的电信号在嗅中枢产生不同的神经动作电位，产生不同的生理与药理作用。
申请号为201510461693.9的发明专利公开了一种中药香的配方及其制备方法，所述的中药香是由下列按重量份的原料制备而成：桂枝10-15份、甘松20-25份、木香5-15份、大黄15-20份、白芷10-20份、干艾草1-5份、八角茴香1-5份、七里香1-5份、改性植物粘粉10-25份。该发明通过高速破碎中药药材得粒料，使用改性植物粘粉提高了中药香的力学强度，但其并未改善药香燃烧排放时颗粒释放的技术问题。
发明内容
针对现有技术中存在的上述不足，本发明所要解决的技术问题是提供一种用于改善心脑血管循环的药香及其制备方法。
本发明目的是通过如下技术方案实现的：
一种用于改善心脑血管循环的药香，其特征在于，所述药香包括桑枝、桂枝、山栀子、大黄、钻地风、干姜、黄芪、紫菀、鸡血藤、高良姜、白芷、川断、川芎、千年健、杜仲、独活、木香、透骨草、木鳖子、乳香、荜拔、降香、没药、榆皮。
一种用于改善心脑血管循环的药香，其特征在于，包括下述重量份的原料：桑枝8-12份、桂枝8-12份、山栀子8-12份、大黄8-12份、钻地风4-6份、干姜4-6份、黄芪4-6份、紫菀4-6份、鸡血藤4-6份、高良姜4-6份、白芷4-6份、川断4-6份、川芎1-3份、千年健1-3份、杜仲1-3份、独活1-3份、木香1-3份、透骨草1-3份、木鳖子1-3份、乳香1-3份、荜拔1-3份、降香1-3份、没药1-3份、榆皮1-3份。
本发明还提供了一种制备上述用于改善心脑血管循环的药香的方法，包括以下步骤：
(1)称取各重量份的中药原料；
(2)将中药原料分别粉碎，过100-200目筛，得到中药细粉，将中药细粉以50-200转/分钟的转速于30℃-45℃搅拌20-30分钟后，加入中药细粉总重量0.15-0.2倍的粘合材料、中药细粉总重量0.01-0.05倍的助燃剂和中药细粉总重量0.05-0.1倍的蒸馏水，继续以50-200转/分钟的转速于35℃-45℃搅拌20-30分钟，得到混合料；
(3)将混合料投入到制香机中，在压力0.2-0.3MPa、保压时间4-8秒、温度45℃-60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于65℃-75℃烘制8-12小时，即得药香。
本发明还提供了一种制备上述用于改善心脑血管循环的药香的方法，包括以下步骤：
(1)称取各重量份的中药原料；
(2)将中药原料置于陶瓷容器中，加入中药原料总重量0.3-0.5倍的粮食酒和中药原料总重量0.1-0.2倍的蜂蜜，混合均匀后密封放置12-24小时，得到混合料A；将混合料A取出，在温度为45-50℃、相对湿度为60-75％的环境下放置48-72小时晾干；
(3)将晾干后的混合料A粉碎，过100-200目筛，得到中药细粉，将中药细粉以50-200转/分钟的转速于30℃-45℃搅拌20-30分钟后，加入中药细粉总重量0.15-0.2倍的粘合材料、中药细粉总重量0.01-0.05倍的助燃剂和中药细粉总重量0.05-0.1倍的蒸馏水，继续以50-200转/分钟的转速于35℃-45℃搅拌20-30分钟，得到混合料B；
(4)将混合料B投入到制香机中，在压力0.2-0.3MPa、保压时间4-8秒、温度45℃-60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于65℃-75℃烘制8-12小时，即得药香。
本发明还提供了一种制备上述用于改善心脑血管循环的药香的方法，包括以下步骤：
(1)称取各重量份的中药原料；
(2)将中药原料置于陶瓷容器中，加入中药原料总重量0.3-0.5倍的粮食酒和中药原料总重量0.1-0.2倍的蜂蜜，混合均匀后密封放置12-24小时，得到混合料A；将混合料A取出，在温度为45-50℃、相对湿度为60-75％的环境下放置48-72小时晾干；
(3)将晾干后的混合料A粉碎，过100-200目筛，得到中药细粉，将中药细粉以50-200转/分钟的转速于30℃-45℃搅拌20-30分钟后，加入中药细粉总重量0.15-0.2倍的粘合材料、中药细粉总重量0.01-0.05倍的助燃剂和中药细粉总重量0.05-0.1倍的蒸馏水，继续以50-200转/分钟的转速于35℃-45℃搅拌20-30分钟，得到混合料B；
(4)将混合料B投入到制香机中，在压力0.2-0.3MPa、保压时间4-8秒、温度45℃-60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于65℃-75℃烘制8-12小时，即得药香；
(5)将药香置于温度为16-25℃、相对湿度为75-80％且通风良好的地窖中放置4-6个月。
优选地，所述药香形式可为线香、柱香、塔香、盘香、香丸或香篆。
优选地，所述粘合材料为瓜尔豆胶、聚丙烯酰胺、香楠粉、卡拉胶中的一种或多种。
优选地，所述粮食酒为高粱酒、玉米酒或小麦酒中的一种或多种。
优选地，所述助燃剂为硝酸钾。
具体的，在本发明中：
桑枝，拉丁学名：Morus alba L，为桑科植物桑Morus alba L.的干燥嫩枝。入肝经。味清苦，微寒，无毒。主治风寒湿痹、四肢拘挛、脚气浮肿、关节酸痛麻木。
桂枝，拉丁学名：CassiaTwig，别称玉桂，为樟科植物肉桂Cinnamomum cassiaPresl的干燥嫩枝。归心、肺、膀胱经。气热，味辛甘，性温。主治散寒解表、温通经脉、通阳化气、寒湿痹痛、四肢厥冷。
山栀子，拉丁学名：Gardenia jasminoides，别称木丹，为茜草科植物栀子Gardenia jasminoides Ellis的干燥成熟果实，其根也可入药。入心、肝、肺、胃经。味苦，性寒。主治热病虚烦不眠、黄疸、淋病、消渴、目赤、咽痛、吐血。
大黄，拉丁学名：RheumpalmatumL.，别称将军，为蓼科植物掌叶大黄Rheumpalmatum L的干燥根及根茎。归胃、大肠、肝、脾经。味苦，性寒。主治实热便秘、热结胸痞、湿热泻痢、黄疸、淋病、水肿腹满。
钻地风，拉丁学名：Rubus phoenicolasius Maxim.，别称迫地枫，为双子叶植物药蔷薇科植物多腺悬钩子Rubus phoenicolasius Maxim.的根、叶。入肝，肾二经。味辛，性温。主治风湿痛、肾虚、阳萎、月经不调。
干姜，拉丁学名：Zingiber officinale Rosc..，是姜科多年生草本植物姜Zingiber officinale Rosc.的干燥根茎。归脾、胃、心、肺经。味辛，性热。主治脘腹冷痛、呕吐、泄泻、亡阳厥逆、寒饮喘咳、寒湿痹痛。
黄芪，拉丁学名：Leguminosae，别称黄耆，为豆科植物蒙古黄芪Astragalusmembranaceus(Fisch.)Bge.var.mongholicus(Bge.)Hsiao或膜荚黄芪Astragalusmembranaceus(Fisch.)Bge.的干燥根。归肺、脾经。味甘，性微温。主治气虚乏力、食少便溏、中气下陷、久泻脱肛、便血崩漏。
紫菀，拉丁学名：Aster tataricus L.,f.，别称青苑，为菊科植物紫菀Astertataricus L.f.的干燥根及根茎。归肺经。性温，味苦、辛。主治肺伤咳嗽、吐血咳嗽、产后下血、缠喉风痹。
鸡血藤，拉丁学名：MillettiareticuiataBenth，别称山鸡血藤，为豆科植物密花豆Spatholobus suberectus Dunn的干燥藤茎。归肝、肾经。味苦、甘，性温。主治月经不调、血虚萎黄、麻木瘫痪、风湿痹痛。
高良姜，拉丁学名：Alpinia officinarum Hance，别称风姜，为姜科植物高良姜Alpinia officinarum Hance的干燥根茎。归脾、胃经。味辛，性热。主治脘腹冷痛、胃寒呕吐、嗳气吞酸。
白芷，拉丁学名：Angelica dahurica，别称川白芷，为伞型科植物白芷Angelicadahurica(Fisch.ex Hoffm.)Benth.et Hook.f.或杭白芷Angelica dahurica(Fisch.exHoffm.)Benth.et Hook.f.var.formosana(Boiss.)Shan et Yuan的干燥根。归胃、大肠、肺经。味辛，性温。主治头痛、牙痛、鼻渊、肠风痔漏、赤白带下、痈疽疮疡、皮肤瘙痒。
川断，拉丁学名：Radix Dipsaci Asperoidis，别称续断，为川续断科植物川续断Dipsacus asperoides C.Y.Cheng et T.M.Ai.的干燥根。归肝、肾经。味苦、辛，性微温。主治腰背酸痛、足膝无力、胎漏、崩漏、跌打损伤、金疮、痔漏、痈疽疮肿。
川芎，拉丁学名：Rhizoma Chuanxiong，别称山鞠穷，为伞形科植物川芎(Ligusticum chuanxiong)的干燥根茎。归肝、胆、心包经。味辛，性温。主治头痛、月经不调、经闭痛经、产后瘀滞腥痛。
千年健，拉丁学名：Homalomena occulta(Lour.)Schott，别称一包针，为天南星科平丝芋属植物千年健Homalomena occulta(Lour.)Schott的干燥根茎。入肝、肾、胃经。味辛，性温。主治风湿痹痛、肢节酸育、筋骨痿软、跌打损伤、胃痛、痈疽疮肿。
杜仲，拉丁学名：Eucommia ulmoides，别称丝楝树皮，为杜仲科植物杜仲EucommiaulmoidesOliv.的干燥树皮。归肝、肾经。味甘，性温。主治腰脊酸疼、足膝痿弱、小便余沥、阴下湿痒、胎漏欲堕。
独活，拉丁学名：Heracleumhemsleyanum，别称独摇草，为伞形科植物重齿毛当归Angelica pubescens Maxim.f.biserrata Shan et Yuan的干燥根。归肝、肾、膀胱经。味辛、苦，性微温。主治风寒湿痹、腰膝疼痛、少阴伏风头痛、头痛齿痛。
木香，拉丁学名：CommonVladimiriaRoot，别称蜜香，为菊科植物木香Aucklandialappa Decne.的干燥根。归脾、胃、肝、肺经。味辛、苦，性温。主治胞胁胀满足、肚腹胀痛、呕吐泄泻、痢疾后重。
透骨草，拉丁学名：Phryma leptostachya L.subsp.asiatica(Hara)Kitamu，别称药曲草，为杜鹃花科植物樟叶越橘Vaccinium dunalianum Wight及尾叶越橘Vacciniumdunalianum Wight var.urophyllum Rehd.et Wils.的全株。入肺、肝经。味甘、辛，性温。主治祛风除湿、活血止痛、舒筋活络、解毒化疹。
木鳖子，拉丁学名：Momordica cochinchinensis(Lour.)Spreng.，别称木鳖藤，为葫芦科植物木鳖子Momordica cochinchinensis(Lour.)Spreng.的种子。入肝、脾、胃经。苦微甘，性温。主治痈肿、疔疮、瘰疬、痔疮、无名肿毒、癣疮、风湿痹痛、筋脉拘挛。
乳香，拉丁学名：Boswelliacarteri，别称熏陆香，为橄榄科植物乳香树Boswelliacarterii Birdw及同属植物Boswellia bhaurdajiana Birdw树皮渗出的树脂。入心、肝、脾经。味苦，性温。主治气血凝滞、心腹疼痛、痈疮肿毒、跌打损伤、痛经、产后瘀血刺痛。
荜拔，拉丁学名：Piper longum L.，别称荜拔梨，为胡椒科植物荜茇Piper longumL.的干燥近成熟或成熟果穗。归脾、胃经。性热，味辛。主治寒闭证、心腹卒痛、中风、中气。
降香，拉丁学名：Dalbergia odorifera，别称降真香，为豆科植物降香檀Dalbergia odorifera T.Chen树干和根的干燥心材。归肝、脾经。味辛，性温。主治脘腹疼痛、肝郁胁痛、胸痹刺痛、跌扑损伤、外伤出血。
没药，拉丁学名：Commiphora myrrha Engl.[C.molmol Engl.，别称末药，为橄榄科植物没药树CommiphoramyrrhaEngl.的胶树脂。入肝、脾、心、肾经。味苦、辛，性平。主治跌打损伤、金疮、筋骨、心腹诸痛、症瘕、经闭、痈疽肿痛、痔漏、目障。
榆皮，为榆科植物榆树Ulmus pumila L.的树皮。味甘，性平，无毒。主治大小便不通，利水道，除邪气。
粉碎机，采用山东临清宏源制药设备有限公司提供的型号为CW500的中药粉碎机。
搅拌机，采用广州市大祥电子机械设备有限公司提供的型号为VH-100B的搅拌机。
制香机，采用武汉天隆翔盛机械设备有限公司提供的型号为XS-99901的制香机。
烘干房，采用杨凌博通农业装备科技有限公司提供的型号为BT-RFGZ的烘干房。
玉米酒，采用贵州芙蓉江酒业有限公司提供的酒精含量为45％的玉米酒。
蜂蜜，采用常州圣贝特蜂产品有限公司提供的产品编号为GB14963、规格为500g的椴树蜜。
硝酸钾，CAS号：7757-79-1，采用国药集团化学试剂有限公司提供的产品编号为1001721933的硝酸钾。
瓜尔豆胶，CAS号：9000-30-0，采用上海源叶生物科技有限公司提供的目数为200目的瓜尔豆胶。
聚丙烯酰胺，CAS号：9003-05-8，采用上海迈瑞尔化学技术有限公司提供的产品编号为M29078、,分子量1400万的非离子型聚丙烯酰胺。
香楠粉，采用湖南永州市欣竹香粉厂提供的目数为200目的香楠粉。
卡拉胶，CAS号：11114-20-8，采用北京华威锐科化工有限公司提供的产品编号为HWG13258、目数为200目的卡拉胶。
本发明所述用于改善心脑血管循环的药香，气味芳香，使用时患者从呼吸道闻吸药物气味，直接作用于鼻、支气管及肺部，从而达到疏通血管、疏通经络的功效，可以促进机体血液循环，有利于气血顺畅。
具体实施方式
实施例1
用于改善心脑血管循环的药香的制备方法，包括以下步骤：
(1)称取各重量份的中药原料：桑枝9份、桂枝9份、山栀子9份、大黄9份、钻地风6份、干姜6份、黄芪6份、紫菀6份、鸡血藤6份、高良姜6份、白芷6份、川断6份、川芎3份、千年健3份、杜仲3份、独活3份、木香3份、透骨草3份、木鳖子3份、乳香3份、荜拔3份、降香3份、没药3份、榆皮3份；
(2)将中药原料分别粉碎，过100目筛，得到中药细粉，将中药细粉以100转/分钟的转速于45℃搅拌30分钟后，加入中药细粉总重量0.2倍的香楠粉、中药细粉总重量0.01倍的硝酸钾和中药细粉总重量0.1倍的蒸馏水，继续以100转/分钟的转速于45℃搅拌30分钟，得到混合料；
(3)将混合料投入到制香机中，在压力0.3MPa、保压时间6秒、温度60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于70℃烘制8小时，即得药香。
实施例2
(1)称取各重量份的中药原料：桑枝9份、桂枝9份、山栀子9份、大黄9份、钻地风6份、干姜6份、黄芪6份、紫菀6份、鸡血藤6份、高良姜6份、白芷6份、川断6份、川芎3份、千年健3份、杜仲3份、独活3份、木香3份、透骨草3份、木鳖子3份、乳香3份、荜拔3份、降香3份、没药3份、榆皮3份；
(2)将中药原料置于陶瓷容器中，加入中药原料总重量0.5倍的玉米酒和中药原料总重量0.2倍的蜂蜜，混合均匀后密封放置24小时，得到混合料A；将混合料A取出，在温度为45℃、相对湿度为60％的环境下放置72小时晾干；
(3)将晾干后的混合料A粉碎，过100目筛，得到中药细粉，将中药细粉以100转/分钟的转速于45℃搅拌30分钟后，加入中药细粉总重量0.2倍的香楠粉、中药细粉总重量0.01倍的硝酸钾和中药细粉总重量0.1倍的蒸馏水，继续以100转/分钟的转速于45℃搅拌30分钟，得到混合料B；
(4)将混合料B投入到制香机中，在压力0.3MPa、保压时间6秒、温度60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于70℃烘制8小时，即得药香。
实施例3
(1)称取各重量份的中药原料：桑枝9份、桂枝9份、山栀子9份、大黄9份、钻地风6份、干姜6份、黄芪6份、紫菀6份、鸡血藤6份、高良姜6份、白芷6份、川断6份、川芎3份、千年健3份、杜仲3份、独活3份、木香3份、透骨草3份、木鳖子3份、乳香3份、荜拔3份、降香3份、没药3份、榆皮3份；
(2)将中药原料置于陶瓷容器中，加入中药原料总重量0.5倍的玉米酒和中药原料总重量0.2倍的蜂蜜，混合均匀后密封放置24小时，得到混合料A；将混合料A取出，在温度为45℃、相对湿度为60％的环境下放置72小时晾干；
(3)将晾干后的混合料A粉碎，过100目筛，得到中药细粉，将中药细粉以100转/分钟的转速于45℃搅拌30分钟后，加入中药细粉总重量0.2倍的香楠粉、中药细粉总重量0.01倍的硝酸钾和中药细粉总重量0.1倍的蒸馏水，继续以100转/分钟的转速于45℃搅拌30分钟，得到混合料B；
(4)将混合料B投入到制香机中，在压力0.3MPa、保压时间6秒、温度60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于70℃烘制8小时，即得药香；
(5)将药香置于温度为16℃、相对湿度为75％且通风良好的地窖中放置6个月后，取出使用。
实施例4
与实施例3基本相同，区别仅在于将所述粘合剂由香楠粉替换为聚丙烯酰胺。
实施例5
与实施例3基本相同，区别仅在于将所述粘合剂由香楠粉替换为瓜尔豆胶。
该药香不易折，表面裂纹有少量细小裂纹，成型性能较好，燃烧时烟雾少，香气清淡怡人。
实施例6
与实施例3基本相同，区别仅在于将所述粘合剂由香楠粉替换为卡拉胶。
该药香易折成2-3厘米长的小段，表面裂纹较粗，燃烧时烟雾较多。
实施例7
更优选地，所述粘合剂为瓜尔豆胶和卡拉胶的混合物，其中瓜尔豆胶和卡拉胶的质量比为(1-3)：(1-3)。
与实施例3基本相同，区别仅在于将所述粘合剂由香楠粉替换为瓜尔豆胶和卡拉胶的混合物，其中所述瓜尔豆胶和卡拉胶的质量比为1:1。
该药香易不易折，成型性好，质地均匀细腻，燃烧时烟雾少，香气浓郁。
对药香燃烧排放PM2.5进行测试：选体积21m3的无人房间进行，测试前房间PM2.5浓度为22μg/m3，该实施例的3根样品；燃烧完全后立即用PM2.5采样器(采用青岛精诚仪器仪表有限公司提供的JH-120F中流量粉尘采样器)进行采样。药香燃烧完全后，房间内PM2.5浓度为45μg/m3。
测试例1
对实施例1-7的药香燃烧排放PM2.5进行测试：选体积21m3的无人房间进行，测试前房间PM2.5浓度为22μg/m3，每次点燃一个实施例的4根样品；燃烧完全后立即用PM2.5采样器(采用青岛精诚仪器仪表有限公司提供的JH-120F中流量粉尘采样器)进行采样。实施例1-7的药香燃烧完全后，房间内PM2.5浓度测试结果见表1。
表1：PM2.5测试结果表
测试例2
对实施例1-7的药香进行治疗效果测试：选择年龄55-79岁的心脑血管疾病患者，随机分成7组，每组50名。患者的病情均符合以下情况：①患者有血管堵塞、心悸、气短、意识障碍、头晕和吞咽困难等症状。②患者不是因交通事故等意外事故患上心脑血管疾病的。③患者未接受过手术治疗。患者在性别、年龄、病情等方面无显著差异(P>0.05)，具有可比性。
分别使用实施例1-7的药香，每天使用1根，针对患者进行药灸。2个月后治疗效果数据见表1。
将患者的治疗效果分为显效、好转和无效三个等级。①显效：患者的临床症状基本消失，可以正常生活。②好转：患者的临床症状明显好转。③无效：患者的临床症状未见好转，或出现严重的并发症。
表2：患者病情数据表
从表2可知，实施例2的治疗效果优于实施例1，这可能是由于粮食酒可以抑制和杀灭霉菌以及虫卵，凝固蛋白，形成霉菌和虫卵无法生长繁荣的环境，并且蜂蜜能改善人体血液的成份，促进人体心脑和血管功能；实施例3的治疗效果更佳，这可能是由于窖藏有利于除杂增香，从而增加了药香的疗效；进一步比较实施例3-6，实施例5中采用瓜尔豆胶其药效更为显著，这可能是因为瓜尔豆胶作为粘合剂提高了药香的组织均匀程度，且燃烧时产生颗粒物较少。
测试例3
高血压病是一种发病率高、致残率高、危害性大的世界范围的疾病，也是心、脑血管病最重要的危险因子，严重威胁着人类的健康。2000年全球疾病负担调查结果显示，50％的心血管疾病是由高血压引起的。
选择身体健康，嗅觉正常的受试者，年龄18-30岁，随机分成3组，每组50名，每组男女比例1/1。受试者实验前至少安静休息20分钟，在测量前24小时内禁止吸烟或饮咖啡，排空膀胱。使三组受试者在相同的密闭空间里分别闻吸实施例1-3的药香，闻吸时间持续30分钟。三组受试者试验前的收缩压、舒张压、脉搏均无显著性差异，具有可比较性(p＞0.05)，可以进行试验。
试验采用天津九安医疗电子股份有限公司提供的型号为KD-391的电子血压计，袖带使用22cm×12cm，缚于受试者左上臂，记录闻吸前、闻吸后收缩压、舒张压和心率变化。计量资料以每组的平均值表示。
具体测试结果见表3。
表3：受试者病情数据表
从表3可以看出，受试者在闻吸药香后，其收缩压明显下降，舒张压也略有下降，但脉搏并无明显变化。现有技术中的降压药大多通过口服给药、且具有毒副作用，而使用者使用本发明药香时通过闻吸的方式摄入，使用方便，从而达到降低血压、增强血管弹性、改变血液循环的目的，可有效预防心脑血管疾病。
Claims (9)
1.一种用于改善心脑血管循环的药香，其特征在于，所述药香包括桑枝、桂枝、山栀子、大黄、钻地风、干姜、黄芪、紫菀、鸡血藤、高良姜、白芷、川断、川芎、千年健、杜仲、独活、木香、透骨草、木鳖子、乳香、荜拔、降香、没药、榆皮。
2.一种用于改善心脑血管循环的药香，其特征在于，包括下述重量份的原料：桑枝8-12份、桂枝8-12份、山栀子8-12份、大黄8-12份、钻地风4-6份、干姜4-6份、黄芪4-6份、紫菀4-6份、鸡血藤4-6份、高良姜4-6份、白芷4-6份、川断4-6份、川芎1-3份、千年健1-3份、杜仲1-3份、独活1-3份、木香1-3份、透骨草1-3份、木鳖子1-3份、乳香1-3份、荜拔1-3份、降香1-3份、没药1-3份、榆皮1-3份。
3.一种制备如权利要求2所述用于改善心脑血管循环的药香的方法，其特征在于，包括以下步骤：
(1)称取各重量份的中药原料；
(2)将中药原料分别粉碎，过100-200目筛，得到中药细粉，将中药细粉以50-200转/分钟的转速于30℃-45℃搅拌20-30分钟后，加入中药细粉总重量0.15-0.2倍的粘合材料、中药细粉总重量0.01-0.05倍的助燃剂和中药细粉总重量0.05-0.1倍的蒸馏水，继续以50-200转/分钟的转速于35℃-45℃搅拌20-30分钟，得到混合料；
(3)将混合料投入到制香机中，在压力0.2-0.3MPa、保压时间4-8秒、温度45℃-60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于65℃-75℃烘制8-12小时，即得药香。
4.一种制备如权利要求2所述用于改善心脑血管循环的药香的方法，包括以下步骤：
(1)称取各重量份的中药原料；
(2)将中药原料置于陶瓷容器中，加入中药原料总重量0.3-0.5倍的粮食酒和中药原料总重量0.1-0.2倍的蜂蜜，混合均匀后密封放置12-24小时，得到混合料A；将混合料A取出，在温度为45-50℃、相对湿度为60-75％的环境下放置48-72小时晾干；
(3)将晾干后的混合料A粉碎，过100-200目筛，得到中药细粉，将中药细粉以50-200转/分钟的转速于30℃-45℃搅拌20-30分钟后，加入中药细粉总重量0.15-0.2倍的粘合材料、中药细粉总重量0.01-0.05倍的助燃剂和中药细粉总重量0.05-0.1倍的蒸馏水，继续以50-200转/分钟的转速于35℃-45℃搅拌20-30分钟，得到混合料B；
(4)将混合料B投入到制香机中，在压力0.2-0.3MPa、保压时间4-8秒、温度45℃-60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于65℃-75℃烘制8-12小时，即得药香。
5.一种制备如权利要求2所述用于改善心脑血管循环的药香的方法，包括以下步骤：
(1)称取各重量份的中药原料；
(2)将中药原料置于陶瓷容器中，加入中药原料总重量0.3-0.5倍的粮食酒和中药原料总重量0.1-0.2倍的蜂蜜，混合均匀后密封放置12-24小时，得到混合料A；将混合料A取出，在温度为45-50℃、相对湿度为60-75％的环境下放置48-72小时晾干；
(3)将晾干后的混合料A粉碎，过100-200目筛，得到中药细粉，将中药细粉以50-200转/分钟的转速于30℃-45℃搅拌20-30分钟后，加入中药细粉总重量0.15-0.2倍的粘合材料、中药细粉总重量0.01-0.05倍的助燃剂和中药细粉总重量0.05-0.1倍的蒸馏水，继续以50-200转/分钟的转速于35℃-45℃搅拌20-30分钟，得到混合料B；
(4)将混合料B投入到制香机中，在压力0.2-0.3MPa、保压时间4-8秒、温度45℃-60℃的工艺条件下挤压成型，将成型后的香胚送入烘干房，于65℃-75℃烘制8-12小时，即得药香；
(5)将药香置于温度为16-25℃、相对湿度为75-80％且通风良好的地窖中放置4-6个月。
6.根据权利要求3-5中任一项所述的用于改善心脑血管循环的药香的的制备方法，其特征在于，所述药香形式为线香、柱香、塔香、盘香、香丸或香篆。
7.根据权利要求6所述的用于改善心脑血管循环的药香的的制备方法，其特征在于，所述粘合材料为瓜尔豆胶、聚丙烯酰胺、香楠粉、卡拉胶中的一种或多种。
8.根据权利要求6所述的用于改善心脑血管循环的药香的的制备方法，其特征在于，所述粮食酒为高粱酒、玉米酒或小麦酒中的一种或多种。
9.根据权利要求6所述的用于改善心脑血管循环的药香的的制备方法，其特征在于，所述助燃剂为硝酸钾。
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107970377A (zh) * | 2018-01-22 | 2018-05-01 | 尹淑珍 | 养心护心药香及其生产工艺 |
| CN108888797A (zh) * | 2018-08-23 | 2018-11-27 | 广西宾阳县紫香缘香业有限公司 | 中药灭菌净化空气养生香及其制备方法 |
| CN111329932A (zh) * | 2020-04-09 | 2020-06-26 | 天津文科泳康科技有限公司 | 一种经肺部经络生宣肃降可吸食吐纳的纯中医药制配方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1657076A (zh) * | 2004-02-17 | 2005-08-24 | 陕西茗久达医药科技发展有限公司 | 一种具有保健功能的药香 |
| CN105012984A (zh) * | 2015-07-31 | 2015-11-04 | 厦门美真香佛具艺品有限公司 | 一种中药香的配方及其制备方法 |
| CN105396035A (zh) * | 2015-12-08 | 2016-03-16 | 赵银河 | 一种太极能量香灸及其生产工艺和使用方法 |
-
2017
- 2017-03-07 CN CN201710132228.XA patent/CN107007798A/zh active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1657076A (zh) * | 2004-02-17 | 2005-08-24 | 陕西茗久达医药科技发展有限公司 | 一种具有保健功能的药香 |
| CN105012984A (zh) * | 2015-07-31 | 2015-11-04 | 厦门美真香佛具艺品有限公司 | 一种中药香的配方及其制备方法 |
| CN105396035A (zh) * | 2015-12-08 | 2016-03-16 | 赵银河 | 一种太极能量香灸及其生产工艺和使用方法 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107970377A (zh) * | 2018-01-22 | 2018-05-01 | 尹淑珍 | 养心护心药香及其生产工艺 |
| CN108888797A (zh) * | 2018-08-23 | 2018-11-27 | 广西宾阳县紫香缘香业有限公司 | 中药灭菌净化空气养生香及其制备方法 |
| CN111329932A (zh) * | 2020-04-09 | 2020-06-26 | 天津文科泳康科技有限公司 | 一种经肺部经络生宣肃降可吸食吐纳的纯中医药制配方法 |
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