CN107007794A - It is a kind of to treat Chinese herbal ointment of scar and preparation method thereof - Google Patents
It is a kind of to treat Chinese herbal ointment of scar and preparation method thereof Download PDFInfo
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- CN107007794A CN107007794A CN201710410769.4A CN201710410769A CN107007794A CN 107007794 A CN107007794 A CN 107007794A CN 201710410769 A CN201710410769 A CN 201710410769A CN 107007794 A CN107007794 A CN 107007794A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A61K36/537—Salvia (sage)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8964—Anemarrhena
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
Present invention offer is a kind of to treat Chinese herbal ointment of scar and preparation method thereof, by 3 10 parts powdered of Ligusticum wallichii, 1 1.5 parts of pangolin, 3 15 parts of curcuma zedoary, 3 10 parts of Rhizoma Sparganii, 0.3 0.6 parts of leech, 3 10 parts of myrrh, 3 10 parts of frankincense, 5 15 parts of the red sage root, 39 parts of safflower, 9 30 parts of the Radix Astragali, 6 12 parts of the wind-weed, 10 15 parts of root of Chinese trichosanthes, 5 15 parts of dandelion, 0.15 0.3 parts of borneol, 10 15 parts of garden burnet, 9 15 parts of selfheal, 5 15 parts of Java brucea, the bulk drug that 3 10 parts of turmeric stirs after being mixed with propane diols, azone, the Chinese herbal ointment for the scar that obtains medical treatment；The Chinese herbal ointment prepared using the present invention treats scar, and scarring areas is not in itch, congested red and swollen symptom during medication and after drug withdrawal, and scar fading effect is obvious.
Description
Technical field
The present invention relates to a kind of Chinese herbal ointment for treating scar and preparation method thereof.
Background technology
Scar refers to a kind of pathological tissues that human body skin soft tissue is formed in processes of wound repair, including Hypertrophic scar
Trace and keloid.Hyperplastic scar is more because of burn, scalds, wound, acne, infection suppuration or because of use operation, laser, cold
Freeze, make skin graft, hormonal medicaments cause damaged tissues hyperplasia after closing or hypodermis destroys denaturation and formed, clinical manifestation is
Skin is protruded, color is red or dark red, itches or shouting pain, part capillary substantially stretches out, drink or eat the excitant such as pungent and eat
Symptom has exacerbation to be inclined to after thing；Keloid is substantially a kind of mesocytoma on skin, comes across after front or shoulder more,
There is small red dot at the beginning with itching, it is gradually ascending, change software strategy into software-hardware strategy, color is red or dark red, in rope strip, butterfly-like, toroidal or not
Regular shape.
At present, clinically the medicine of common treatment scar mainly has injection medicine, coating medicine.CN105477478A is disclosed
A kind of Chinese medicine ointment for desalinating scar, the Chinese medicine ointment takes the Chinese medicine material of following weight proportions to be prepared from：Chinese holly 15-
25 parts, 15-25 parts of Golden Larch Bark, 10-20 parts of the red sage root, peach branch 10-20 parts, 10-20 parts of blood clam, 5-15 parts of myrrh, cape jasmine 5-15
Part, 5-15 parts of Radix zanthoxyli, 2-7 parts of cactus, 2-7 parts of folium artemisiae argyi, 1-5 parts of resina liquidamberis, 1-5 parts of aloe, 1-5 parts of turtle shell, Rhizoma Sparganii 1-5
Part, 1-2 parts of safflower, evil 2-3 parts of courage, 2-3 parts of peach kernel, 1-2 parts of madder, 3-4 parts of the bletilla striata, 3-4 parts of corydalis tuber, 3-4 parts of dragon's blood,
8-12 parts of sesame oil；CN102475673A disclose it is a kind of be used to repair the liquid film of scar, by zeins, borneol,
Safflower, ginseng, pseudo-ginseng, rhizoma zingiberis, spirulina maxim, azone, allantoin, Bis(hydroxymethyl)imidazolidinyl urea, glycerine and ethanol group
Into, wherein, the percentage by weight of the component is：Zeins, which accounts for 2-8%, borneol and accounts for 1-5%, safflower, accounts for 1-
5%th, ginseng account for 1-3%, pseudo-ginseng account for 0.1-3%, rhizoma zingiberis account for 1-5%, spirulina maxim account for 1-5%, azone account for 1-3%,
Allantoin, which accounts for 0.05-0.5%, Bis(hydroxymethyl)imidazolidinyl urea and accounts for 0.05-0.5%, glycerine and account for 10-20%, ethanol, to be accounted for
55-70%.Inventor find patient using above-mentioned Chinese medicine ointment or liquid film treatment scar, after drug withdrawal easily occur itch,
Congested symptom, and scar fading effect is not obvious.
In addition, the medicine of the common treatment scar of in the market has asiaticoside ointment and scar plaster（As scar gram, Kang Ruibao,
Scar must not）, but patient use these medicines during, it may appear that local itch and stimulate etc. adverse reaction.
The content of the invention
For problems of the prior art, it is an object of the invention to provide a kind of Chinese herbal ointment for treating scar；
It is a further object of the present invention to provide a kind of preparation method of the Chinese herbal ointment.
To achieve these goals, the present invention is adopted the following technical scheme that：
A kind of Chinese herbal ointment for treating scar, it is characterised in that：It is mixed by Chinese patent drug powder, propane diols and azone；
The Chinese patent drug powder is according to weight part ratio meter：Wherein, Ligusticum wallichii 3-10 parts, 1-1.5 parts of pangolin, 3-15 parts of curcuma zedoary, three
3-10 parts of rib, 0.3-0.6 parts of leech, 3-10 parts of myrrh, 3-10 parts of frankincense, 5-15 parts of the red sage root, 3-9 parts of safflower, 9-30 parts of the Radix Astragali,
6-12 parts of the wind-weed, 10-15 parts of root of Chinese trichosanthes, 5-15 parts of dandelion, 0.15-0.3 parts of borneol, 10-15 parts of garden burnet, selfheal 9-15
Part, 5-15 parts of Java brucea, 3-10 parts of turmeric.
The Chinese herbal ointment treatment scar that patient is prepared using such scheme, scarring areas is not in itch, filled after drug withdrawal
The symptom of blood, and scar fading effect is obvious.
Further, the Chinese patent drug powder is according to weight part ratio meter：Including 3-10 parts of Ligusticum wallichii, 1-1.5 parts of pangolin, cowherb
3-15 parts of art, 3-10 parts of Rhizoma Sparganii, 0.3-0.6 parts of leech, 3-10 parts of myrrh, 3-10 parts of frankincense, 5-15 parts of the red sage root, 3-9 parts of safflower,
9-30 parts of the Radix Astragali, 6-12 parts of the wind-weed, 10-15 parts of root of Chinese trichosanthes, 5-15 parts of dandelion, 0.15-0.3 parts of borneol, 10-15 parts of garden burnet,
9-15 parts of selfheal.
Preferably, the Chinese patent drug powder is according to weight part ratio meter：It is 5-8 parts including Ligusticum wallichii, 1.2-1.3 parts of pangolin,
8-10 parts of curcuma zedoary, 5-8 parts of Rhizoma Sparganii, 0.4-0.5 parts of leech, 5-8 parts of myrrh, 5-8 parts of frankincense, 9-11 parts of the red sage root, 5-7 parts of safflower,
18-22 parts of the Radix Astragali, 8-10 parts of the wind-weed, 12-13 parts of root of Chinese trichosanthes, 9-11 parts of dandelion, 0.2-0.25 parts of borneol, garden burnet 12-13
Part, 11-13 parts of selfheal, 5-15 parts of Java brucea, 10-30 parts of motherwort, 3-10 parts of turmeric.
Preferably, the Java brucea is 9-11 parts, and the motherwort is 18-22 parts, and the turmeric is 5-8 parts.
More preferably described Chinese patent drug powder is according to weight part ratio meter：It is 6 parts, 1.2 parts of pangolin, curcuma zedoary 8 including Ligusticum wallichii
Part, 7 parts of Rhizoma Sparganii, 0.5 part of leech, 5 parts of myrrh, 8 parts of frankincense, 10 parts of the red sage root, 6 parts of safflower, 18 parts of the Radix Astragali, 9 parts of the wind-weed, root of Chinese trichosanthes
12 parts, 9 parts of dandelion, 0.2 part of borneol, 13 parts of garden burnet, 11 parts of selfheal, 10 parts of Java brucea, 7 parts of turmeric, motherwort is 20
Part.
A kind of preparation method for the Chinese herbal ointment for treating scar, is first made powder by dried Chinese patent drug raw material, then will
Propane diols and azone are according to volume ratio=4.29-30:Added after 1 mixing in herb powder, Chinese herbal ointment is obtained after stirring.
Preferably, the volume ratio of the propane diols and azone is 8-12.5:1.
In order to reach more preferable curative effect, bulk drug is first harvested as follows and Chinese patent drug powder is respectively prepared：
Ligusticum wallichii：Excavate rhizome May, remove silt in drying after fibrous root, solarization；Garden burnet：In spring will germinate when or autumn plant
Excavate, except fibrous root, dried after cleaning section after withered；Selfheal：Harvested when summer fruit ear is in brownish red, remove and shone after impurity
It is dry；Java brucea：Harvest, dried after removing impurity when autumn fruit maturation；Pangolin：Scale and shell is removed, the removal of impurity is gone, cleans and shines
It is dry；Curcuma zedoary：Harvested after autumn and winter cauline leaf is withered, remove soil, boiled to the saturating heart, fibrous root is removed after drying；Rhizoma Sparganii：In winter
Stem tuber is dug out to secondary spring, removes cauline leaf fibrous root, is cleaned, and prune and dried after crust；Leech：Cleaned in after season in spring and autumn seizure,
Dead segment is scalded with boiling water to dry；Turmeric：Excavate, boiled after cleaning to the saturating heart when winter cauline leaf is withered, remove fibrous root and dry；Not yet
Medicine：The light white chromoresin that bark crack or wound ooze out is collected in winter or summer, air set is placed on hard into rufous
Block, goes to pulverize after the removal of impurity and dries；Frankincense：Yu Chun, summer collect in the skin zone of trunk；The red sage root：Yu Chun, the excavation of season in autumn two, are removed
Decontamination and residual stem, clean, run through, and are dried after section；Safflower：Plucked when summer, flower was red by xanthochromia, pick most impurity, remove stem
Dried after leaf, base of a fruit head；Motherwort：Luxuriant in summer cauline leaf, Hua Weikai or first is plucked when opening, and removes impurity, is dried after segment；It is yellow
Stilbene：Uprooted in spring and autumn, remove soil, go after fibrous root to dry；The wind-weed：The wind-weed of growth more than 3 years is excavated in season in spring and autumn two
Rhizome；Dried after removing stem seedling and fibrous root；Root of Chinese trichosanthes：In the excavation of season autumn and winter two, fibrous root is removed, is dried after scraping off crust, section；
Dandelion：Spend and excavated when just opening in the spring to autumn, remove fibrous root, dried after cleaning；Borneol：Kapur trunk or branch are cut
Piece, crystallizes through distillation, borneol is obtained after cooling；
Take 6 parts of Ligusticum wallichii respectively again, 1.2 parts of pangolin, 8 parts of curcuma zedoary, 7 parts of Rhizoma Sparganii, 0.5 part of leech, 5 parts of myrrh, 8 parts of frankincense is red
10 parts of ginseng, 6 parts of safflower, 18 parts of the Radix Astragali, 9 parts of the wind-weed, 12 parts of root of Chinese trichosanthes, 9 parts of dandelion, 0.2 part of borneol, 13 parts of garden burnet, the summer is withered
11 parts of grass, 10 parts of Java brucea, 7 parts of turmeric, 20 parts of motherwort is well mixed, then by 1,3-PD and azone according to volume ratio
=10-12:Added after 1 mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
The Chinese herbal ointment prepared using the present invention treats scar, and scarring areas is not in itch, congested disease after drug withdrawal
Shape, and scar fading effect is obvious.Scar is treated using the Chinese herbal ointment for preparing of the present invention, after medication 1 month, keloid is bright
Aobvious to reduce softening, scratchiness disappears；After medication 5 months, incrustation comes off, and keloid disappears substantially, epidermis soft smooth；It is discontinued
Afterwards so far without recurrence.
It is also not in itch that the Chinese herbal ointment prepared using the present invention, which is treated in scar, therapeutic process, congested red and swollen
Symptom.
The Chinese herbal ointment of present invention treatment scar is by taking Ligusticum wallichii, and pangolin, curcuma zedoary, Rhizoma Sparganii, leech, myrrh, frankincense is red
Ginseng, safflower, the Radix Astragali, the wind-weed, root of Chinese trichosanthes, dandelion, borneol, garden burnet, selfheal, Java brucea, turmeric, motherwort, propane diols and
The synergy of azone repairs scar, and evident in efficacy, cure rate is up to 98.5%, and the recurrence rate after medication is only 0.5%.
The preparation method of the Chinese herbal ointment of present invention treatment scar is simple, it is easy to implement, and the bulk drug is common
Chinese patent drug, production cost is low.
Brief description of the drawings
Fig. 1 is that certain scar patient uses the situation map before the Chinese herbal ointment treatment in embodiment 1；
Fig. 2 is that certain scar patient uses the situation map after the Chinese herbal ointment medication 1 month in embodiment 1；
Fig. 3 is that certain scar patient uses the situation map after the Chinese herbal ointment medication 2 months in embodiment 1；
Fig. 4 is that certain scar patient uses the situation map after the Chinese herbal ointment medication 3 months in embodiment 1.
Embodiment
It is pointed out here that following examples are it is not intended that limiting the scope of the invention, those of ordinary skill in the art
Some nonessential modifications and adaptations are made according to present disclosure, all fallen in the scope of protection of the present invention.Unless otherwise specified,
Heretofore described fraction is parts by weight, and the percentage is weight percentage；Heretofore described bulk drug is this
The commercially available Chinese patent drug that field those of ordinary skill knows, also can be by being made after voluntarily gathering；Propane diols of the present invention is 1,
The one or more combination of ammediol, propane diols.
Embodiment 1：
Bulk drug is first harvested as follows and is made into Chinese patent drug powder respectively；
Ligusticum wallichii：Excavate rhizome May, remove silt in drying after fibrous root, solarization；Garden burnet：In spring will germinate when or autumn plant
Excavate, except fibrous root, dried after cleaning section after withered；Selfheal：Harvested when summer fruit ear is in brownish red, remove and shone after impurity
It is dry；Java brucea：Harvest, dried after removing impurity when autumn fruit maturation；Pangolin：Scale and shell is removed, the removal of impurity is gone, cleans and shines
It is dry；Curcuma zedoary：Harvested after autumn and winter cauline leaf is withered, remove soil, boiled to the saturating heart, fibrous root is removed after drying；Rhizoma Sparganii：In winter
Stem tuber is dug out to secondary spring, removes cauline leaf fibrous root, is cleaned, and prune and dried after crust；Leech：Cleaned in after season in spring and autumn seizure,
Dead segment is scalded with boiling water to dry；Turmeric：Excavate, boiled after cleaning to the saturating heart when winter cauline leaf is withered, remove fibrous root and dry；Not yet
Medicine：The light white chromoresin that bark crack or wound ooze out is collected in winter or summer, air set is placed on hard into rufous
Block, goes to pulverize after the removal of impurity and dries；Frankincense：Yu Chun, summer collect in the skin zone of trunk；The red sage root：Yu Chun, the excavation of season in autumn two, are removed
Decontamination and residual stem, clean, run through, and are dried after section；Safflower：Plucked when summer, flower was red by xanthochromia, pick most impurity, remove stem
Dried after leaf, base of a fruit head；Motherwort：Luxuriant in summer cauline leaf, Hua Weikai or first is plucked when opening, and removes impurity, is dried after segment；It is yellow
Stilbene：Uprooted in spring and autumn, remove soil, go after fibrous root to dry；The wind-weed：The wind-weed of growth more than 3 years is excavated in season in spring and autumn two
Rhizome；Dried after removing stem seedling and fibrous root；Root of Chinese trichosanthes：In the excavation of season autumn and winter two, fibrous root is removed, is dried after scraping off crust, section；
Dandelion：Spend and excavated when just opening in the spring to autumn, remove fibrous root, dried after cleaning；Borneol：Kapur trunk or branch are cut
Piece, crystallizes through distillation, borneol is obtained after cooling；
Take 6 grams of powdered Ligusticum wallichii, 1.2 grams of pangolin, 8 grams of curcuma zedoary, 7 grams of Rhizoma Sparganii, 0.5 gram of leech, 5 grams of myrrh, breast respectively again
It is fragrant 8 grams, 10 grams of the red sage root, 6 grams of safflower, 18 grams of the Radix Astragali, 9 grams of the wind-weed, 12 grams of root of Chinese trichosanthes, 9 grams of dandelion, 0.2 gram of borneol, garden burnet
13 grams, 11 grams of selfheal, 10 grams of Java brucea, 7 grams of turmeric obtains Chinese patent drug powder after 20 grams of motherwort is well mixed, then will
Added after 220ml propane diols and the mixing of 22ml azones in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Embodiment 2：
With reference to embodiment 1, Chinese patent drug powder is made in the data in table 1, then by 1,3-PD（240ml）And azone
（30ml）Added after mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Embodiment 3：With reference to embodiment 1, Chinese patent drug powder is made in the data in table 1, then by 1,3-PD
（250ml）And azone（25ml）Added after mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Embodiment 4：
With reference to embodiment 1, Chinese patent drug powder is made in the data in table 1, then by 1,3-PD（150ml）And azone
（10ml）Added after mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Embodiment 5：
With reference to embodiment 1, Chinese patent drug powder is made in the data in table 1, then by 1,3-PD（300ml）And azone
（35ml）Added after mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Embodiment 6：
With reference to embodiment 1, Chinese patent drug powder is made in the data in table 1, then by 1,3-PD（150ml）And azone
（35ml）Added after mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Embodiment 7：
With reference to embodiment 1, Chinese patent drug powder is made in the data in table 1, then by propane diols（300ml）And azone（10ml）
Added after mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Embodiment 8-10：
With reference to embodiment 1, Chinese patent drug powder is made in the data in table 1 respectively, then respectively by 1,3-PD（240ml）
And azone（30ml）Added after mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
Curative effect is tested：
The standard of curative effect evaluation：Excellent effect, the symptom such as keloid pain, itch is wholly absent, and keloid softens completely, is touched
Softness without tubercle, after drug withdrawal in 6 months without during recurrence, and medication and be discontinued after be not in itch, congestive symptom；
Effective, the symptom such as keloid pain, itch disappears or substantially mitigated, scarring areas 60-70%（Area percentage）Part
Softening flattens, without itch, congestive symptom occurs during recurrence, and medication once in a while in 6 months after drug withdrawal；It is invalid, scar lump
The symptoms such as carbuncle pain, itch slightly mitigate even unchanged, and scar quality, size only have slight change or even unchanged, and use
Occur itch, congestive symptom during medicine.Cure rate：In treatment phase in average every hundred scar patients, it is judged to suffering from through doctor
Ratio after person's drug withdrawal；Recurrence rate：After drug withdrawal in average every hundred scar patients, the ratio of symptom patients with recurrent.
Curative effect method of testing：
In April, -2016 in June, 2015 is come into our hospital（Including going to our hospital）Medical keloid patient adopts as treatment group
Treated respectively with the Chinese herbal ointment of the present invention, specifically take the Chinese herbal ointment of appropriate present invention treatment scar to be externally applied to patient
Keloid at, bandaged with gauze, weekly debridement dressing once, while observing and recording the desalination situation of scar.
Wherein, patient Zhang, man, 23 years old, knee super large keloid, readme early stage was used during scar gram scar plaster
Occur after itch, hyperemia, hyperplastic conditions, medication 3 months without improvement.Our hospital is gone to afterwards using in the preparation of the embodiment of the present invention 1
Into medicinal ointment therapy, such as Fig. 1 before medication, scar enlargement is hard；After medication 1 month, keloid softening is reduced, scratchiness disappears,
Such as Fig. 2；After medication 2 months, the obvious atrophy of keloid diminishes, ulceration after skin formation table shallow water blister；After medication 3 months, skin
Damage notable atrophy to diminish, incrustation is started shedding off at surface skin ulceration, gradually repair and take a turn for the better, such as Fig. 3；After medication 4 months, incrustation
Completely fall off, keloid disappears substantially, epidermis soft smooth, excellent effect；So far without recurrence, such as Fig. 4 after drug withdrawal.In addition,
Patient Chen, female, 47 years old, chest keloid in more than 10 years of the course of disease, was treated using the Chinese herbal ointment in the embodiment of the present invention 1,
After medication 1 month, keloid substantially softens, and after medication 3 months, keloid is obviously reduced, softening, no tubercle, no secondary to make
It is evident in efficacy with appearance, so far without recurrence；Patient week certain, man, 7 years old, face's keloid, use the present invention treatment after 1
Month, the softening of keloid quality, atrophy, after 3 months, keloid substantially diminishes, no projection, so far without recurrence, effect
It is excellent.
Control group
The keloid patient that in June, -2015 in October, 2013 goes to a doctor in other general hospitals, using commercially available scar gram, Kang Rui
Luxuriant growth or scar must not the scar plaster of board treated, or treated using commercially available asiaticoside ointment, record it and treated
Symptom and treatment results in journey.
Curative effect test result：According to the statistics to therapeutic process and result, obtain curative effect test result and be shown in Table 2；
As shown in Table 2, the Chinese herbal ointment for treating scar using the present invention treats scar, and good effect, fading effect is obvious, and big absolutely
Most of patients is during medication and after drug withdrawal without itch, congestive symptom.During the medication of 200 patients, only 1 trouble
Person is recurred, and 1 patient's treatment is invalid, and remaining patient, without itch, congested red and swollen symptom, uses during medication and after drug withdrawal
Treated effect reaches 98.5% after medicine, and recurrence rate is only 0.5%.And there are 79 patients to occur scabies during medication in control group
Itch, red and swollen symptom, its effective percentage is only 60.5%, and inefficiency is up to 46.3%.By contrast, the present invention treatment scar in into
Ointment has significant effect.
Claims (8)
1. a kind of Chinese herbal ointment for treating scar, it is characterised in that：It is by Chinese patent drug powder, propane diols and azone mixing and
Into；
The Chinese patent drug powder is according to weight part ratio meter：Including 3-10 parts of Ligusticum wallichii, 1-1.5 parts of pangolin, 3-15 parts of curcuma zedoary, Rhizoma Sparganii
3-10 parts, 0.3-0.6 parts of leech, 3-10 parts of myrrh, 3-10 parts of frankincense, 5-15 parts of the red sage root, 3-9 parts of safflower, 9-30 parts of the Radix Astragali, know
Female 6-12 parts, 10-15 parts of root of Chinese trichosanthes, 5-15 parts of dandelion, 0.15-0.3 parts of borneol, 10-15 parts of garden burnet, 9-15 parts of selfheal,
5-15 parts of Java brucea, 3-10 parts of turmeric.
2. the Chinese herbal ointment for the treatment of scar according to claim 1, it is characterised in that the Chinese patent drug powder is according to weight
Part is than meter：Wherein, Ligusticum wallichii 3-10 parts, 1-1.5 parts of pangolin, 3-15 parts of curcuma zedoary, 3-10 parts of Rhizoma Sparganii, 0.3-0.6 parts of leech, myrrh
3-10 parts, 3-10 parts of frankincense, 5-15 parts of the red sage root, 3-9 parts of safflower, 9-30 parts of the Radix Astragali, 6-12 parts of the wind-weed, 10-15 parts of root of Chinese trichosanthes, Pu
Public English 5-15 parts, 0.15-0.3 parts of borneol, 10-15 parts of garden burnet, 9-15 parts of selfheal.
3. the Chinese herbal ointment for the treatment of scar according to claim 1, it is characterised in that the Chinese patent drug powder is according to weight
Part is than meter：Wherein, Ligusticum wallichii is 5-8 parts, and 1.2-1.3 parts of pangolin, 8-10 parts of curcuma zedoary, 5-8 parts of Rhizoma Sparganii, 0.4-0.5 parts of leech does not have
5-8 parts of medicine, 5-8 parts of frankincense, 9-11 parts of the red sage root, 5-7 parts of safflower, 18-22 parts of the Radix Astragali, 8-10 parts of the wind-weed, 12-13 parts of root of Chinese trichosanthes,
9-11 parts of dandelion, 0.2-0.25 parts of borneol, 12-13 parts of garden burnet, 11-13 parts of selfheal, 5-15 parts of Java brucea, motherwort 10-
30 parts, 3-10 parts of turmeric.
4. the Chinese herbal ointment of the treatment scar according to claim 1,2 or 3, it is characterised in that：The Java brucea is 9-11
Part, the motherwort is 18-22 parts, and the turmeric is 5-8 parts.
5. the Chinese herbal ointment for the treatment of scar according to claim 4, it is characterised in that the Chinese patent drug powder is according to weight
Part is than meter：Wherein, Ligusticum wallichii is 6 parts, 1.2 parts of pangolin, 8 parts of curcuma zedoary, 7 parts of Rhizoma Sparganii, 0.5 part of leech, 5 parts of myrrh, 8 parts of frankincense,
10 parts of the red sage root, 6 parts of safflower, 18 parts of the Radix Astragali, 9 parts of the wind-weed, 12 parts of root of Chinese trichosanthes, 9 parts of dandelion, 0.2 part of borneol, 13 parts of garden burnet, summer
11 parts of withered grass, 10 parts of Java brucea, 7 parts of turmeric, motherwort is 20 parts.
6. the preparation method of the Chinese herbal ointment of scar is treated as described in claim any one of 1-5, it is characterised in that：First by drying
Powder is made in Chinese patent drug raw material afterwards, then by propane diols and azone according to volume ratio=4.29-30:Herb powder is added after 1 mixing
In, obtain Chinese herbal ointment after stirring.
7. the preparation method of the Chinese herbal ointment of scar is treated according to claim 6, it is characterised in that：The propane diols and nitrogen
The volume ratio of ketone is 8-12.5:1.
8. the preparation method of the Chinese herbal ointment of scar is treated according to claim 7, it is characterised in that：First as follows
Simultaneously Chinese patent drug powder is respectively prepared in harvesting bulk drug：
Ligusticum wallichii：Excavate rhizome May, remove silt in drying after fibrous root, solarization；Garden burnet：In spring will germinate when or autumn plant
Excavate, except fibrous root, dried after cleaning section after withered；Selfheal：Harvested when summer fruit ear is in brownish red, remove and shone after impurity
It is dry；Java brucea：Harvest, dried after removing impurity when autumn fruit maturation；Pangolin：Scale and shell is removed, the removal of impurity is gone, cleans and shines
It is dry；Curcuma zedoary：Harvested after autumn and winter cauline leaf is withered, remove soil, boiled to the saturating heart, fibrous root is removed after drying；Rhizoma Sparganii：In winter
Stem tuber is dug out to secondary spring, removes cauline leaf fibrous root, is cleaned, and prune and dried after crust；Leech：Cleaned in after season in spring and autumn seizure,
Dead segment is scalded with boiling water to dry；Turmeric：Excavate, boiled after cleaning to the saturating heart when winter cauline leaf is withered, remove fibrous root and dry；Not yet
Medicine：The light white chromoresin that bark crack or wound ooze out is collected in winter or summer, air set is placed on hard into rufous
Block, goes to pulverize after the removal of impurity and dries；Frankincense：Yu Chun, summer collect in the skin zone of trunk；The red sage root：Yu Chun, the excavation of season in autumn two, are removed
Decontamination and residual stem, clean, run through, and are dried after section；Safflower：Plucked when summer, flower was red by xanthochromia, pick most impurity, remove stem
Dried after leaf, base of a fruit head；Motherwort：Luxuriant in summer cauline leaf, Hua Weikai or first is plucked when opening, and removes impurity, is dried after segment；It is yellow
Stilbene：Uprooted in spring and autumn, remove soil, go after fibrous root to dry；The wind-weed：The wind-weed of growth more than 3 years is excavated in season in spring and autumn two
Rhizome；Dried after removing stem seedling and fibrous root；Root of Chinese trichosanthes：In the excavation of season autumn and winter two, fibrous root is removed, is dried after scraping off crust, section；
Dandelion：Spend and excavated when just opening in the spring to autumn, remove fibrous root, dried after cleaning；Borneol：Kapur trunk or branch are cut
Piece, crystallizes through distillation, borneol is obtained after cooling；
Take 6 parts of Szechwan Lovage Rhizome, 1.2 parts of pangolin powder, 8 parts of Zedoary Rhizome, 7 parts of Rhizoma Sparganii powder, Leech 0.5 respectively again
Part, 5 parts of Myrrh, 8 parts of frankincense, 10 parts of Danshen Root, 6 parts of saffron powder, 18 parts of Milkvetch Root, 9 parts of Common Anemarrhena Rhizome,
12 parts of Snakegourd Root, 9 parts of dandelion powder, 0.2 part of borneol powder, 13 parts of garden burnet powder, 11 parts of selfheal powder, crow courage
Sub- 10 parts of powder, 7 parts of Turmeric Root, 20 parts of motherwort powder is well mixed, then by 1,3-PD and azone according to volume
Than=10-12:Added after 1 mixing in Chinese patent drug powder, Chinese herbal ointment is obtained after stirring.
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Cited By (4)
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| CN108066714A (en) * | 2018-03-02 | 2018-05-25 | 周雷 | A kind of Chinese medicine composition for being used to treat the scars day after tomorrow |
| CN108772349A (en) * | 2018-06-20 | 2018-11-09 | 天马（安徽）国药科技股份有限公司 | A kind of processing of astragalus membranaceus powder spends mud cleaning machine |
| CN111840497A (en) * | 2020-08-25 | 2020-10-30 | 谢武林 | Medicine for treating scars and preparation method thereof |
| CN115837064A (en) * | 2022-11-17 | 2023-03-24 | 刘燕 | Traditional Chinese medicine formula for softening hyperplasia scars and preparation method thereof |
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| CN1089489A (en) * | 1993-01-04 | 1994-07-20 | 李威 | A kind of ointment for the treatment of skin scar |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108066714A (en) * | 2018-03-02 | 2018-05-25 | 周雷 | A kind of Chinese medicine composition for being used to treat the scars day after tomorrow |
| CN108772349A (en) * | 2018-06-20 | 2018-11-09 | 天马（安徽）国药科技股份有限公司 | A kind of processing of astragalus membranaceus powder spends mud cleaning machine |
| CN111840497A (en) * | 2020-08-25 | 2020-10-30 | 谢武林 | Medicine for treating scars and preparation method thereof |
| CN115837064A (en) * | 2022-11-17 | 2023-03-24 | 刘燕 | Traditional Chinese medicine formula for softening hyperplasia scars and preparation method thereof |
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| CN107007794B (en) | 2020-04-14 |
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Denomination of invention: The invention relates to a Zhongcheng ointment for treating scars and a preparation method thereof Effective date of registration: 20220215 Granted publication date: 20200414 Pledgee: Chongqing Branch of China Everbright Bank Co.,Ltd. Pledgor: CHONGQING HUABANG COSMETIC MEDICINE TECHNOLOGY CO.,LTD. Registration number: Y2022500000007 |
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