CN107007762A - A kind of Chinese medicine composition, its preparation method and application for treating fracture - Google Patents
A kind of Chinese medicine composition, its preparation method and application for treating fracture Download PDFInfo
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- CN107007762A CN107007762A CN201710456497.1A CN201710456497A CN107007762A CN 107007762 A CN107007762 A CN 107007762A CN 201710456497 A CN201710456497 A CN 201710456497A CN 107007762 A CN107007762 A CN 107007762A
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Abstract
The Chinese medicine composition for the treatment fracture that the present invention is provided is using safflower, frankincense, myrrh, Radix Angelicae Sinensis and dragon's blood as monarch drug in a prescription, and using eupolyphoge sinensis, keel, catechu, the bletilla striata and radix ampelopsis as ministerial drug, assistant makes Chinese gall and drynaria baronii.Safflower is promoting blood circulation and removing blood stasis, accelerates blood circulation, enhances metabolism；Chinese angelica blood supplementing is invigorated blood circulation, clearing and activating the channels and collaterals；Frankincense has analgesia, anti-inflammatory, increasing leukocyte, promotes the effect of wound healing；Myrrh has anti-inflammation, and the effect for the treatment of trauma is controlled in convergence；Dragon's blood has an effect of hemostasia and promoting granulation, and safflower, frankincense, myrrh, Radix Angelicae Sinensis and the mutual compatibility of dragon's blood, which can be cooperateed with, to be reached promoting blood circulation and removing blood stasis, is enhanced metabolism, the effect quickly subsided a swelling.Eupolyphoge sinensis, keel, catechu, the bletilla striata and the mutual compatibility of radix ampelopsis, which have, to be accelerated to restrain, and myogenic promotes the effect of muscles and bones growth.Chinese gall and the collaboration of drynaria baronii compatibility reach antibacterial, the effect of anti-inflammatory.The weight that each taste Chinese medicine is provided according to the present invention can cooperate with the effect for reaching the tumble injury of fast treating bruise and fracture than compatibility.
Description
Technical field
The present invention relates to tcm field, and in particular to a kind of to treat Chinese medicine composition of fracture and preparation method thereof.
Background technology
Fracture is exactly that the structure of head of phalanx or bone is broken completely or partially.Children and the elderly are more common in, it is young and middle-aged
Happen occasionally.Patient is often-individual position fracture, and minority is multiple fracture, and through appropriate processing in time, most patients can recover
Function originally, a few patients can leave different degrees of sequelae.
Fracture is general to be occurred suddenly, to make patient's mood acute variation, certain injury is caused to the body and mind of patient.Wound
The pain that caused fracture and the damaging surrounding tissue accompanied can cause pain to cause patient；Meanwhile, the damage of fracture site
And bleeding, make to hinder the glue locally different degrees of reactive swelling of appearance.The various treatments carried out after above-mentioned various reactions and wound
The activity of such as bed traction, plaster fixing due to limiting fourth limbs, can produce some harmful effects, lack whole body hinder in addition after
Sexuality, and living environment, custom, rhythm etc. change, and can cause patient's loss of appetite, occur digestive function weakness,
The disorders of digestion phenomenon such as abdominal distension, constipation, causes patient's insufficiency of intake and malnutrition.In addition, long-term bed braking can also
Cause hypostatic pneumonia, skin road feel dye or calculus, thrombophlebitis of leg, it is useless levied with comprehensive, the complication such as bedsore.Thus may be used
To find out, fracture can bring larger injury to patient.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating fracture.
It is a further object of the present invention to provide a kind of preparation method for the Chinese medicine composition for treating fracture.
Another object of the present invention is to provide a kind of Chinese medicine composition for treating fracture in treatment fracture medicine is prepared
Using.
The Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, by the original for including following parts by weight
Material is made：8-12 parts of Radix Angelicae Sinensis, 8-12 parts of safflower, 8-12 parts of frankincense, 8-12 parts of myrrh, 5-8 parts of eupolyphoge sinensis, 5-8 parts of keel, Chinese gall
10-15 parts of 10-15 parts, 2-4 parts of dragon's blood, 5-8 parts of catechu, 8-12 parts of the bletilla striata, 5-8 parts of radix ampelopsis and drynaria baronii.
The Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, it is preferable that by following parts by weight
Raw material be made：8.5-10 parts of Radix Angelicae Sinensis, 8.5-10 parts of safflower, 8.5-10 parts of frankincense, 8.5-10 parts of myrrh, 6-7 parts of eupolyphoge sinensis, keel
5-7 parts, 11-13 parts of Chinese gall, 2.5-3.5 parts of dragon's blood, 5-7 parts of catechu, 8.5-10 parts of the bletilla striata, 5.5-7.5 parts of radix ampelopsis and drynaria baronii
11-13 parts.
The Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, it is preferable that by following parts by weight
Raw material be made：9 parts of Radix Angelicae Sinensis, 9 parts of safflower, 9 parts of frankincense, 9 parts of myrrh, 6 parts of eupolyphoge sinensis, 6 parts of keel, 12 parts of Chinese gall, dragon's blood 3
12 parts of part, 6 parts of catechu, 9 parts of the bletilla striata, 6 parts of radix ampelopsis and drynaria baronii.
The preparation method of the Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, methods described bag
Include following steps：
(1) safflower extract is prepared：According to weight ratio, in the ethanol that safflower is added to 10-15 times, boiling is heated to, is protected
Warm 30-50min, filtering, obtains filtrate, filter residue is carried out into second extraction, obtains filtrate, merges filtrate twice, concentrates, and dries,
Obtain safflower extract；
(2) Catechu extract is prepared：According to weight ratio, by catechu limb, crust is removed, crushes, is added to 15-20 times
In deionized water, boiling is heated to, 40-60min is incubated, filters to get filtrate, filter residue is subjected to second extraction, obtain filtrate, is closed
And filtrate twice, paste is concentrated into, the Catechu extract is obtained；
(3) Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii dry, pulverize respectively, sieves, obtain
To drug powder；
(4) drug powder for obtaining step (3) is added in the vinegar of 30-50 times of parts by weight, is heated to boiling, and insulation is endured
60-120min processed, adds frankincense and myrrh, and stirring boils 5-10min, concentrates, and then adds the safflower extraction that step (1) is obtained
The Catechu extract that thing and step (2) are obtained, stirring boils 2-5min, that is, obtains the Chinese medicine composition of the treatment fracture.
There is the active drug composition of a variety for the treatment of traumatic injuries and fracture in safflower and catechu, but in safflower and catechu
Effective ingredient be difficult to extract by common immersion, therefore by they carry out boil be difficult cause it is therein effectively into
Divide and be fully used.The present invention extracts the active ingredient of safflower first with the mode of alcohol extracting twice, utilizes water extraction twice
Mode extracts the active ingredient of catechu, when preparing the Chinese medicine composition for the treatment of fracture by safflower extract and Catechu extract most
After add, reduce effective ingredient volatilization, strengthen drug effect.When extracting safflower extract, safflower is added to 10-15 times and weighed
In the ethanol for measuring part, boiling is heated to, 30-50min is extracted, the active ingredient of safflower can be substantially dissolved in ethanol solution.
When extracting Catechu extract, it is added to after catechu is handled in 15-20 times of deionized water, is heated to boiling, extracts 40-
60 minutes, the active ingredient in catechu can fully dissolve in deionized water.
Due to containing ethereal oil composition in frankincense and myrrh, long-time heating is easily caused the loss of active ingredient, drops
Low drug effect, extend patient recovery time, the present inventor with small fire by Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata,
After radix ampelopsis and drynaria baronii are boiled, frankincense and myrrh are added, drug effect is improved, the loss of effective ingredient is reduced, accelerates to fall
Play damage and the recovery of fracture.
The preparation method of the Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, it is preferable that step
Suddenly in (1), the volume fraction of ethanol is 50-75%.
The preparation method of the Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, it is preferable that step
Suddenly in (1), the heating rate of the heating is 10-20 DEG C/min.
The preparation method of the Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, it is preferable that step
Suddenly in (1), the temperature of the drying is 30-45 DEG C, and the time is 24-36h.
The present invention dries 24-36h using 30-45 DEG C of low temperature, the damage of effective ingredient effectively in reduction drying process
Lose.
The preparation method of the Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, it is preferable that step
Suddenly in (3), the mesh number of sieving is 80-120 mesh.
The preparation method of the Chinese medicine composition for the treatment of fracture according to the specific embodiment of the invention, it is preferable that step
Suddenly in (4), the heating rate of the heating is 2-5 DEG C/min.
In order to allow the active ingredient of medicine to be substantially dissolved in vinegar, the present invention boils Chinese medicine composition, medicine using small fire
Active ingredient can be substantially dissolved in wherein, lifted drug effect.
According to the specific embodiment of the invention treatment fracture Chinese medicine composition prepare treatment fracture medicine
In application.
The Chinese medicine composition that the present invention is provided is understood for convenience, and the raw material and effect in the present invention are further explained
State.
Radix Angelicae Sinensis is sweet and weighs, therefore can enrich blood, and its gas is light and pungent, thus again can promoting circulation of blood, bowl spares has, has benefit in row, in being blood
Key medicine.Thus, it can enrich blood, and can invigorate blood circulation, and can both stimulate the menstrual flow, and can be active.Modern medicine research shows that angelica root contains and waved
Neutral oil component in hair oil and involatile constituent, volatile oil has：Butylidenephthalide (Butylidene phthalide), β-
Firpene (β-Pinene), australene, camphane (Camphene), to P-cymene (p-Cymene), β-sailor's mandarin orange lactone
(Bergapten) other compositions etc., are still contained, such as：Stigmasterol (Stigmasterol), sitosterol (Sitosterol), stigmasterol-
D glycosides (Stigma-sterol-D-glucoside), tetradecyl alchohol -1 (Tetradecanol-1), elegant jessamine light element
(Scopletin) etc., in addition, also containing sucrose (Sucrose), fructose (Fructose), glucose (Glucose)；Vitamin
A, vitamin B12, vitamin E；17 kinds of amino acid and sodium, potassium, calcium, magnesium etc. more than 20 plant inorganic elements.
Safflower, warm-natured, pungent, invigorate blood circulation, blood stasis removing analgesic.By promoting blood circulation and removing blood stasis, accelerate blood circulation, promote new old generation
Thank, increase excludes the melanin produced by melanocyte, promote to be stranded in internal melanin decomposition, be allowed to precipitate to be formed
Color spot, or the pigment in shallow lake is decomposed and is excreted；Strengthen coronary flow, inhibition thrombosis；Anticoagulant is acted on, and promotes blood
Circulation, adjusts immunocompetence, can significant raising hypoxia-bearing capability.The traditional Chinese medical science thinks that safflower has invigorate blood circulation, swelling and pain relieving, beauty to dispel
The effects such as spot, it is adaptable to the cold amenorrhoea of blood, dysmenorrhoea and various congestive pain, including caused by amenorrhea, menorrhalgia, coronary heart disease
Pectoralgia etc..Safflower is rich in glucoside, polysaccharide and organic acid etc..Invigorate blood circulation, stimulate the menstrual flow, silt of dispelling.With lowering blood pressure and blood fat, improve body
The function of microcirculation.
Frankincense is used as conventional Chinese medicine, its nature and flavor acrid, bitter, warm, the thoughts of returning home, liver, the spleen channel, the analgesic of effect blood-activating and qi-promoting, detumescence life
Flesh.《Mingyi Bielu》Say：Frankincense " treats wind addiction sore poison of itching ",《Records of Tradition Chinese and Western Medicine in Combination》Carry：Frankincense has the work(of " myogenic ".Therefore at all times
Since, conventional this product treatment sore diabrosis is not closed up long, and urticaria poison of itching.Modern medicine study shows the resinous 60- of frankincense
70%, gummy 27-35%, volatile oil 3-8%.The main component of resin is free α, β-boswellic acid 33%, with reference to mastic
Acid 1.5%, olibanoresene 33%.Natural gum is the calcium salt and magnesium salts 20% of arabitic acid, bassorin 6%；In addition, still containing
Amaroid 0.5%.Volatile oil has fragrance in faint yellow, containing firpene, racemization-limonene and α, β-phellandrene.Damaged for bruise
Wound, sore carbuncle swells, qi depression to blood stasis pain is demonstrate,proved, and is external wounds key medicine.Its composition mainly has resin, natural gum and volatile oil.Modern pharmacology
Effect：Analgesia, anti-inflammatory, increasing leukocyte, promote wound healing；Reduce damage of the medicine to gastric mucosa.
Myrrh, Classification system：Commiphora myrrha, myrrh is olive subject plant myrrh and belongs to other plant stem together
The oleo-gum-resin that dry crust oozes out.With antibacterial, antimicrobial, anti-inflammatory, convergence, tool balosam speciality, deodorization, ventosity of dispelling,
Sterilization, diuresis, stimulate the menstrual flow, resolving sputum, killing fungus, excitation, sharp stomach, urge sweat, mend body, sharp uterus, vulnerary effect
Eupolyphoge sinensis (ground beetle), it is salty, tremble with fear；It is slightly poisonous, return liver warp.Function is with curing mainly：Broken stasis of blood blood, continuous muscles and bones.For
Injured bone, blood stasis closed, abdominal mass lump in the abdomen.Chinese medicine function：(1) hemostasis under, eliminating mass lump in the abdomen treats injured：For blood stasis, bruise
Damage and abdominal mass lump.(2) blood stasis removing analgesic：Swell and ache and lumbar muscle strain, sprain for liver and spleen caused by blood stasis.
Keel, Classification system：OsDraconis, it is sweet puckery, put down, main hydroxyl calcium phosphate Ca5(PO4)3(OH)；Also containing a small amount of
The element such as calcium carbonate and iron, aluminium, magnesium, manganese, strontium.Tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines, myogenic sore.Control frightened epilepsy demented,
Palpitation is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, and hematemesis is had blood in stool, under uterine bleeding band, and rush down dysentery prolapse of the anus, ulcer does not close up long.
Chinese gall, Classification system, Rhus chinensis Mill., meridian distribution of property and flavor：It is sour, it is puckery, it is cold in nature.Return lung, large intestine,
Kidney channel.Effect：Astringe the lung, hidroschesis, puckery intestines, controlling nocturnal emission with astringent drugs stops blooding, removing toxic substances.Cure mainly：Chronic cough of deficiency lung, spontaneous sweating, protracted dysentery chronic diarrhea, prolapse of the anus,
Seminal emission, gonorrhoea, various bleedings, carbuncle swells boil.Astriction：This product has the general pharmacological action of tannic acid, can make skin, mucous membrane,
The local tissue protein such as ulcer solidifies and plays astriction, can accelerate blood clotting and have anastalsis；Can precipitation biology
Alkali and have solution alkaloid intoxication.Bacteriostasis：Chinese gall decoction to staphylococcus aureus, bacterium flexneri, pig suddenly
Random bacillus and Escherichia coli have inhibitory action.Through proposing that its Chinese gall liquid after rubbing acid still has antibacterial action with ether, it resists
The composition of bacterium effect is primarily present in skin zone, and the boil liquid of center portion is then without antibacterial action.
It is dragon's blood sweet-salty, flat, there is scattered stasis pain, effect of hemostasia and promoting granulation cures mainly traumatic injury, internal injury stasis caused pain；Wound
Haemophilia, scrofula, ulcer on the shank is burst does not conform to etc. disease long.
Catechu, scientific name：Acacia catechu, it is bitter in taste, puckery, it is slightly cold, return lung warp.Major function：Hygroscopic myogenic sore.
For unhealing ulcer, eczema, aphtha, the pain of injury caused by falling and tumbling, traumatism and bleeding.Heartwood (catechu-tannicacid) containing catechutannic acid
20%-50%, left-handed and racemization cachou extract (catechin) 2%-20%, left-handed and racemization epicatechin (epicatechin),
Tannic red tannin (phlobatannin), and fisetin (fisetin), Quercetin (quercetin), quercetagetin
(quercetagetin) flavonols and the Kaempferol (kaempferol), Dihydrokaempferol (dihydrokaempferol), flower such as
Flag pine is plain (taxifolin), Isorhamnetin (isorhamnetin), dextrorotation afzelechin (afzelechin), double focusing original arrow
Che Jusu (dimericprocyanidin).(aflatoxin) containing aflatoxin in bark.In addition, also containing viscous in soft extracts
Liquid matter, fat oil, wax and natural gum etc..Contain hexasaccharide (hexasaccharide) in natural gum again.Contain chlorophyll in leaf
(chlorophylls) a, b, carotenoid.
The bletilla striata, Classification system：Bletilla striata, it is bitter in taste, sweet it is puckery, be slightly cold.Enter liver, stomach, lung channel, function convergence
Hemostasis, detumescence and promoting granulation.Cure mainly interior traumatism and bleeding.
Radix ampelopsis, nature and flavor：Bitter sweet is pungent, cool.Channel tropism：The heart channel of Hang-Shaoyin, lung channel, Liver Channel, the spleen channel.Function：It is clearing heat and detoxicating, eliminating stagnation to stop pain,
Myogenic sore.Cure mainly：Sore swollen toxin, scrofula is scalded, wet sore, a kind of malaria, frightened epilepsy, bloody flux, intestines wind, anal fistula, leukorrhea, traumatic injury,
Traumatism and bleeding.
Drynaria baronii, scientific name：Drynaria sinica Diels, nature and flavor temperature, hardship；Return liver and kidney channel.Major function：Kidney tonifying is strong
Bone, continues and hinders pain relieving.For lumbago due to the kidney deficiency, Hiccough and deaf, tooth mobility, falling winks frustrates, injured bone.
Beneficial effects of the present invention are：
1. the Chinese medicine composition for the treatment fracture that the present invention is provided is using safflower, frankincense, myrrh, Radix Angelicae Sinensis and dragon's blood as monarch drug in a prescription,
Using eupolyphoge sinensis, keel, catechu, the bletilla striata and radix ampelopsis as ministerial drug, assistant makes Chinese gall and drynaria baronii.Safflower is promoting blood circulation and removing blood stasis, accelerates blood circulation,
Enhance metabolism；Radix Angelicae Sinensis has replenishing and activating blood, clearing and activating the channels and collaterals effect；Frankincense has analgesia, anti-inflammatory, increasing leukocyte, promotees
Enter the effect of wound healing；Myrrh has anti-inflammation, and the effect for the treatment of trauma is controlled in convergence；Dragon's blood has the effect of hemostasia and promoting granulation,
Safflower, frankincense, myrrh, Radix Angelicae Sinensis and the mutual compatibility of dragon's blood, which can be cooperateed with, to be reached promoting blood circulation and removing blood stasis, is enhanced metabolism, is quickly subsided a swelling
Effect.Eupolyphoge sinensis, keel, catechu, the bletilla striata and the mutual compatibility of radix ampelopsis, which have, to be accelerated to restrain, and myogenic promotes the effect of muscles and bones growth.Five
Gall nut and the collaboration of drynaria baronii compatibility reach antibacterial, the effect of anti-inflammatory.The weight that each taste Chinese medicine is provided according to the present invention, can than compatibility
Collaboration reaches the tumble injury of fast treating bruise and the effect of fracture.
2. the method for the Chinese medicine composition for the preparation treatment fracture that the present invention is provided, first handles it by safflower and catechu respectively
After obtain safflower extract and Catechu extract, then by Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and Shen
Ginger, be dry, pulverize, and be added in vinegar, and small fire boils to boiling and then boils 60-120min again, and frankincense and myrrh are added and endured
System is eventually adding safflower extract and Catechu extract, this method effectively increases the utilization rate of medicine to melting so that system
The active ingredient of medicine is fully used in standby Chinese medicine composition.Due to containing ethereal oil composition in frankincense and myrrh,
Long-time heating is easily caused the loss of active ingredient, reduces drug effect, extends the recovery time of patient, the present invention by Radix Angelicae Sinensis,
After eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii are boiled, frankincense and myrrh are added, is at utmost remained
The active ingredient of medicine, and first come out the extracts active ingredients of safflower and catechu, it is eventually adding wherein, improves drug effect, plus
The recovery of fast traumatic injury and fracture.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below
Detailed description.Obviously, described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are resulting on the premise of creative work is not made to be owned
Other embodiment, belongs to the scope that the present invention is protected.
Embodiment 1
The Chinese medicine composition of fracture is treated, is made up of the raw material including following parts by weight：Radix Angelicae Sinensis 8g, safflower 8g, frankincense 8g,
Myrrh 8g, eupolyphoge sinensis 5g, keel 5g, Chinese gall 10g, dragon's blood 2g, catechu 5g, bletilla striata 8g, radix ampelopsis 5g and drynaria baronii 10g.
The preparation method of the Chinese medicine composition of above-mentioned treatment fracture, comprises the following steps：
(1) safflower extract is prepared：According to weight ratio, safflower is added into 10 times of volume fraction in 75% ethanol,
Ebuillition of heated, is incubated 30min, and filtering obtains filtrate, filter residue is carried out into second extraction, obtains filtrate, merges filtrate twice, dense
Contracting, dries, obtains safflower extract；
(2) Catechu extract is prepared：According to weight ratio, by catechu limb, crust is removed, is crushed, be added to 15 times and go
In ionized water, boiling is heated to, 40min is incubated, filters to get filtrate, filter residue is subjected to second extraction, filtrate is obtained, merged twice
Filtrate, is concentrated into paste, obtains the Catechu extract；
(3) Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii dry, pulverize respectively, sieves, obtain
To drug powder；
(4) drug powder for obtaining step (3) is added in the vinegar of 30 times of parts by weight, is heated to boiling, and insulation is boiled
60min, adds frankincense and myrrh, and stirring boils 10min, concentrates, and then adds safflower extract and step that step (1) is obtained
(2) Catechu extract obtained, stirring boils 2min, that is, obtains the Chinese medicine composition of the treatment fracture.
Embodiment 2
The Chinese medicine composition of fracture is treated, is made up of the raw material including following parts by weight：Radix Angelicae Sinensis 12g, safflower 12g, frankincense
12g, myrrh 12g, eupolyphoge sinensis 8g, keel 8g, Chinese gall 15g, dragon's blood 4g, catechu 8g, bletilla striata 12g, radix ampelopsis 8g and drynaria baronii 15g.
The preparation method of the Chinese medicine composition of above-mentioned treatment fracture, comprises the following steps：
(1) safflower extract is prepared：According to weight ratio, safflower is added into 15 times of volume fraction in 50% ethanol,
Ebuillition of heated, is incubated 50min, and filtering obtains filtrate, filter residue is carried out into second extraction, obtains filtrate, merges filtrate twice, dense
Contracting, dries, obtains safflower extract；
(2) Catechu extract is prepared：According to weight ratio, by catechu limb, crust is removed, is crushed, be added to 20 times and go
In ionized water, boiling is heated to, 60min is incubated, filters to get filtrate, filter residue is subjected to second extraction, filtrate is obtained, merged twice
Filtrate, is concentrated into paste, obtains the Catechu extract；
(3) Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii dry, pulverize respectively, sieves, obtain
To drug powder；
(4) drug powder for obtaining step (3) is added in the vinegar of 50 times of parts by weight, is heated to boiling, and insulation is boiled
120min, adds frankincense and myrrh, and stirring boils 5min, concentrates, and then adds safflower extract and step that step (1) is obtained
(2) Catechu extract obtained, stirring boils 5min, that is, obtains the Chinese medicine composition of the treatment fracture.
The Chinese medicine composition that the obtained treatment is fractured is coated on gauze, cooling obtains the cream of the treatment fracture
Medicine.
Embodiment 3
The Chinese medicine composition of fracture is treated, is made up of the raw material of following parts by weight：Radix Angelicae Sinensis 8.5g, safflower 8.5g, frankincense
8.5g, myrrh 8.5g, eupolyphoge sinensis 6g, keel 5g, Chinese gall 11g, dragon's blood 2.5g, catechu 5g, bletilla striata 8.5g, radix ampelopsis 5.5g and drynaria baronii
11g。
The preparation method of the Chinese medicine composition of above-mentioned treatment fracture, comprises the following steps：
(1) safflower extract is prepared：According to weight ratio, in the ethanol that safflower is added to 12 times, from room temperature with 10 DEG C/min
Heating rate be heated to boiling, be incubated 40min, filtering, obtain filtrate, filter residue be subjected to second extraction, obtain filtrate, merge
Filtrate, concentrates twice, dries, obtains safflower extract；
(2) Catechu extract is prepared：According to weight ratio, by catechu limb, crust is removed, is crushed, be added to 18 times and go
In ionized water, boiling is heated to, 45min is incubated, filters to get filtrate, filter residue is subjected to second extraction, filtrate is obtained, merged twice
Filtrate, is concentrated into paste, obtains the Catechu extract；
(3) Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii dry, pulverize respectively, crosses 80 mesh
Sieve, obtains drug powder；
(4) drug powder for obtaining step (3) is added in the vinegar of 40 times of parts by weight, from room temperature with 2 DEG C/min liter
Warm speed is heated to boiling, and insulation boils 100min, adds frankincense and myrrh, and stirring boils 8min, concentrates, then adds step
(1) Catechu extract that the safflower extract and step (2) obtained is obtained, stirring boils 3min, that is, obtains the treatment fracture
Chinese medicine composition.
Embodiment 4
The Chinese medicine composition of fracture is treated, is made up of the raw material of following parts by weight：Radix Angelicae Sinensis 10g, safflower 10g, frankincense 10g,
Myrrh 10g, eupolyphoge sinensis 7g, keel 7g, Chinese gall 13g, dragon's blood 3.5g, catechu 7g, bletilla striata 10g, radix ampelopsis 7.5g and drynaria baronii 13g.
The preparation method of the Chinese medicine composition of above-mentioned treatment fracture, comprises the following steps：
(1) safflower extract is prepared：According to weight ratio, in the ethanol that safflower is added to 12 times, from room temperature with 20 DEG C/min
Heating rate ebuillition of heated, be incubated 40min, filtering obtains filtrate, filter residue is carried out into second extraction, obtains filtrate, merges two
Secondary filtrate, concentration, in 30 DEG C of dry 36h, obtains safflower extract；
(2) Catechu extract is prepared：According to weight ratio, by catechu limb, crust is removed, is crushed, be added to 18 times and go
In ionized water, boiling is heated to, 50min is incubated, filters to get filtrate, filter residue is subjected to second extraction, filtrate is obtained, merged twice
Filtrate, is concentrated into paste, obtains the Catechu extract；
(3) Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii dry, pulverize respectively, crosses 120 mesh
Sieve, obtains drug powder；
(4) drug powder for obtaining step (3) is added in the vinegar of 40 times of parts by weight, from room temperature with 5 DEG C/min liter
Warm speed is heated to boiling, and insulation boils 80min, adds frankincense and myrrh, and stirring boils 6min, concentrates, then adds step
(1) Catechu extract that the safflower extract and step (2) obtained is obtained, stirring boils 4min, that is, obtains the treatment fracture
Chinese medicine composition.
Embodiment 5
The Chinese medicine composition of fracture is treated, is made up of the raw material of following parts by weight：Radix Angelicae Sinensis 9g, safflower 9g, frankincense 9g, myrrh
9g, eupolyphoge sinensis 6g, keel 6g, Chinese gall 12g, dragon's blood 3g, catechu 6g, bletilla striata 9g, radix ampelopsis 6g and drynaria baronii 12g.
The preparation method of the Chinese medicine composition of above-mentioned treatment fracture, comprises the following steps：
(1) safflower extract is prepared：According to weight ratio, safflower is added into 12 times of volume fraction in 60% ethanol,
From room temperature with 20 DEG C/min heating rate ebuillition of heated, 35min is incubated, filtering obtains filtrate, filter residue is carried out into secondary carry
Take, obtain filtrate, merge filtrate twice, concentration dries 24h at 45 DEG C, obtains safflower extract；
(2) Catechu extract is prepared：According to weight ratio, by catechu limb, crust is removed, is crushed, be added to 16 times and go
In ionized water, boiling is heated to, 50min is incubated, filters to get filtrate, filter residue is subjected to second extraction, filtrate is obtained, merged twice
Filtrate, is concentrated into paste, obtains the Catechu extract；
(3) Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii dry, pulverize respectively, crosses 100 mesh
Sieve, obtains drug powder；
(4) drug powder for obtaining step (3) is added in the vinegar of 40 times of parts by weight, from room temperature with 3 DEG C/min liter
Warm speed is heated to boiling, and insulation boils 100min, adds frankincense and myrrh, and stirring boils 8min, concentrates, then adds step
(1) Catechu extract that the safflower extract and step (2) obtained is obtained, stirring boils 3min, that is, obtains the treatment fracture
Chinese medicine composition.
The Chinese medicine composition that the obtained treatment is fractured is coated on gauze, cooling obtains the cream of the treatment fracture
Medicine.
The foregoing is only a specific embodiment of the invention, but protection scope of the present invention is not limited thereto, any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all be contained
Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of Chinese medicine composition for treating fracture, it is characterised in that be made up of the raw material including following parts by weight：Radix Angelicae Sinensis 8-12
Part, 8-12 parts of safflower, 8-12 parts of frankincense, 8-12 parts of myrrh, 5-8 parts of eupolyphoge sinensis, 5-8 parts of keel, 10-15 parts of Chinese gall, dragon's blood 2-4
10-15 parts of part, 5-8 parts of catechu, 8-12 parts of the bletilla striata, 5-8 parts of radix ampelopsis and drynaria baronii.
2. the Chinese medicine composition for the treatment of fracture according to claim 1, it is characterised in that by the raw material system of following parts by weight
Into：8.5-10 parts of Radix Angelicae Sinensis, 8.5-10 parts of safflower, 8.5-10 parts of frankincense, 8.5-10 parts of myrrh, 6-7 parts of eupolyphoge sinensis, 5-7 parts of keel, five
11-13 parts of 11-13 parts of gall nut, 2.5-3.5 parts of dragon's blood, 5-7 parts of catechu, 8.5-10 parts of the bletilla striata, 5.5-7.5 parts of radix ampelopsis and drynaria baronii.
3. the Chinese medicine composition for the treatment of fracture according to claim 1, it is characterised in that by the raw material system of following parts by weight
Into：9 parts of Radix Angelicae Sinensis, 9 parts of safflower, 9 parts of frankincense, 9 parts of myrrh, 6 parts of eupolyphoge sinensis, 6 parts of keel, 12 parts of Chinese gall, 3 parts of dragon's blood, catechu 6
12 parts of part, 9 parts of the bletilla striata, 6 parts of radix ampelopsis and drynaria baronii.
4. described in claim 1 treatment fracture Chinese medicine composition preparation method, it is characterised in that methods described include with
Lower step：
(1) safflower extract is prepared：According to weight ratio, in the ethanol that safflower is added to 10-15 times, boiling is heated to, 30- is incubated
50min, filtering, obtains filtrate, filter residue is carried out into second extraction, obtains filtrate, merges filtrate twice, concentrates, and dries, obtains red
Flower extract；
(2) Catechu extract is prepared：According to weight ratio, by catechu limb, remove crust, crush, be added to 15-20 times go from
In sub- water, boiling is heated to, 40-60min is incubated, filters to get filtrate, filter residue is subjected to second extraction, filtrate is obtained, merges two
Secondary filtrate, is concentrated into paste, obtains the Catechu extract；
(3) Radix Angelicae Sinensis, eupolyphoge sinensis, keel, Chinese gall, dragon's blood, the bletilla striata, radix ampelopsis and drynaria baronii dry, pulverize respectively, sieves, obtain medicine
Thing powder；
(4) drug powder for obtaining step (3) is added in the vinegar of 30-50 times of parts by weight, is heated to boiling, and insulation is boiled
60-120min, adds frankincense and myrrh, and stirring boils 5-10min, concentrates, and then adds the safflower extract that step (1) is obtained
The Catechu extract obtained with step (2), stirring boils 2-5min, that is, obtains the Chinese medicine composition of the treatment fracture.
5. the preparation method of the Chinese medicine composition for the treatment of fracture according to claim 4, it is characterised in that in step (1),
The volume fraction of ethanol is 50-75%.
6. the preparation method of the Chinese medicine composition for the treatment of fracture according to claim 4, it is characterised in that in step (1),
The heating rate of the heating is 10-20 DEG C/min.
7. the preparation method of the Chinese medicine composition for the treatment of fracture according to claim 4, it is characterised in that in step (1),
The temperature of the drying is 30-45 DEG C, and the time is 24-36h.
8. the preparation method of the Chinese medicine composition for the treatment of fracture according to claim 4, it is characterised in that in step (3),
The mesh number of sieving is 80-120 mesh.
9. the preparation method of the Chinese medicine composition for the treatment of fracture according to claim 4, it is characterised in that in step (4),
The heating rate of the heating is 2-5 DEG C/min.
10. application of the Chinese medicine composition of the treatment fracture described in claim 1 in treatment fracture medicine is prepared.
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Application publication date: 20170804 |