CN107007690A - A kind of anti-aging pearl oral liquid and preparation method thereof - Google Patents

A kind of anti-aging pearl oral liquid and preparation method thereof Download PDF

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Publication number
CN107007690A
CN107007690A CN201710185905.4A CN201710185905A CN107007690A CN 107007690 A CN107007690 A CN 107007690A CN 201710185905 A CN201710185905 A CN 201710185905A CN 107007690 A CN107007690 A CN 107007690A
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CN
China
Prior art keywords
pearl
solution
preparation
oral liquid
aging
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Pending
Application number
CN201710185905.4A
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Chinese (zh)
Inventor
林湧
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Beihai City Ocean Pearl Lin Technology Co Ltd
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Beihai City Ocean Pearl Lin Technology Co Ltd
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Priority to CN201710185905.4A priority Critical patent/CN107007690A/en
Publication of CN107007690A publication Critical patent/CN107007690A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/19Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses a kind of anti-aging pearl oral liquid, the oral liquid is made up of pearl liquor, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution, on the basis of the weight of pearl liquor, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution account for 35 40%, 18 22%, the 12 16% of pearl liquor respectively;And there is provided its preparation method.Pearl is digested, the composition such as polypeptide, amino acid in pearl enters in enzymolysis liquid, is not destroyed, is more easy to be absorbed by the body, is used in combination with the extract solution of the Radix Astragali, agate card, matrimony vine, with good anti-aging, antifatigue effect.

Description

A kind of anti-aging pearl oral liquid and preparation method thereof
Technical field
The invention belongs to pearl articles technical field, in particular it relates to a kind of anti-aging pearl oral liquid and its preparation side Method.
Background technology
Pearl is a kind of ancient organic gemstone.Mainly produce in pearl shellfish and pearl oyster shellfish mollusk body;And by The mineral bead calciferous for acting on and generating in endocrine, is by a large amount of small aragonite crystals set.Pearl Inorganic constituents be mainly calcium carbonate, magnesium carbonate, more than 91% is accounted for, secondly for silica, calcium phosphate, Al2O3 and Fe2O3 etc.;It is precious Organic matter in pearl includes L-aminobutanedioic acid, threonine, serine, glutamic acid, glycine, alanine, cystine, valine, egg 17 kinds of amino acid such as propylhomoserin, isoleucine, leucine, tyrosine, phenylalanine, histidine, arginine, proline.In addition, Also containing 30 various trace elements, taurine, abundant vitamin, peptides.
《Pharmacopoeia of People's Republic of China》And《Dictionary of medicinal plant》Indicate:Pearl has calm the nerves arresting convulsion, shade removing, solution The effects such as taking poison and growing muscle due, modern study also shows that pearl is improving body immunity, anti-aging, freckle removing and whitening, supplement calcium etc. Aspect all has unique effect.It is most traditional method that pearl milling, which is eaten, but there is the problem of absorptivity is low, even if Pearl is worn into powder more than 400 mesh, its absorptivity is not more than 30%.Hydrolyzed pearl extract can improve the suction of pearl Receive and utilize, but traditional strong acid, highly basic method for hydrolysis can destroy the active ingredient of pearl, will also result in waste.Current enzyme Pearl method is solved, the active ingredient in pearl is further preserves.
The content of the invention
First purpose of the present invention is to provide a kind of anti-aging pearl oral liquid.
Second object of the present invention is to provide the preparation method of above-mentioned oral liquid.
The purpose of the present invention is implemented by the following technical programs:
A kind of anti-aging pearl oral liquid, the oral liquid is by pearl liquor, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution It is made, on the basis of the weight of pearl liquor, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution account for the 35- of pearl liquor respectively 40%、18-22%、12-16%。
It is preferred that, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution account for pearl liquor weight respectively in the oral liquid 37%、22%、15%。
Further, the pearl liquor is enzymolysis pearl liquor.
The preparation method of above-mentioned anti-aging pearl oral liquid, comprises the following steps:
(1)The preparation of pearl liquor:Protease will be added after crushing pearl, pH value is adjusted, is heated to 40-43 DEG C and is stirred 4- 5h, suction filtration adds activated carbon, carries out secondary suction filtration, is heated to 60-65 DEG C of holding 1.5-2h, and Temperature fall obtains pearl liquor;
(2)The preparation of Radix Astragali extractive solution:Added after the Radix Astragali is crushed in 8-10 times of water, 0.5-1h is boiled in heating, filter, be concentrated to give Radix Astragali extractive solution;
(3)The preparation of agate card extract solution:Added after agate card is crushed in 8-10 times of water, 0.5-1h is boiled in heating, filter, be concentrated to give Agate card extract solution;
(4)The preparation of fructus lycii extracted solution:Added after agate card is crushed in 8-10 times of water, 0.5-1h is boiled in heating, filter, be concentrated to give Fructus lycii extracted solution;
(5)By step(1)-(4)Obtained pearl liquor, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution is mixed;
(6)By step(5)Obtained mixed liquor is sterilized, and is produced.
Further, the step(1)In, pH value regulated value 4-4.5.
Further, the step(4)In, the time of mixing is 20-30min.
Further, the step(5)In, method for disinfection uses ultraviolet-sterilization.
The present invention is to digest pearl liquor, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution as raw material, and raw material is to carry Liquid is taken, active ingredient is largely extracted, be more easy to absorb than powder stock.
The invention has the advantages that:
The anti-aging pearl oral liquid that the present invention is provided, is digested to pearl, and the composition such as polypeptide, amino acid in pearl enters In enzymolysis liquid, it is not destroyed, is more easy to be absorbed by the body, is used in combination with the extract solution of the Radix Astragali, agate card, matrimony vine, with good Anti-aging, antifatigue effect.
Embodiment
Raw material in following examples is that market can obtain product.
Embodiment 1
A kind of preparation method of anti-aging pearl oral liquid, comprises the following steps:
(1)The preparation of pearl liquor:Pearl weight 3-5% protease, regulation pH value to 4-4.5, heating will be added after crushing pearl 5h is stirred to 40 DEG C, suction filtration adds activated carbon, carries out secondary suction filtration, is heated to 60 DEG C of holding 2h, Temperature fall obtains precious Pearl liquid.
(2)The preparation of Radix Astragali extractive solution:Added after the Radix Astragali is crushed in 8 times of water, 0.5h is boiled in heating, filter, be concentrated to give Radix Astragali extractive solution.
(3)The preparation of agate card extract solution:Added after agate card is crushed in 8 times of water, 0.5h is boiled in heating, filter, be concentrated to give Agate card extract solution.
(4)The preparation of fructus lycii extracted solution:Added after agate card is crushed in 8 times of water, 0.5h is boiled in heating, filter, be concentrated to give Fructus lycii extracted solution.
(5)By step(1)-(4)Obtained pearl liquor 100g, Radix Astragali extractive solution 35g, agate card extract solution 18g, matrimony vine are extracted Liquid 12g mixes 20min;
(6)By step(5)Obtained mixed liquor carries out ultraviolet-sterilization, produces.
Embodiment 2
A kind of preparation method of anti-aging pearl oral liquid, comprises the following steps:
(1)The preparation of pearl liquor:Pearl weight 3-5% protease, regulation pH value to 4-4.5, heating will be added after crushing pearl 5h is stirred to 42 DEG C, suction filtration adds activated carbon, carries out secondary suction filtration, is heated to 60 DEG C of holding 2h, Temperature fall obtains precious Pearl liquid.
(2)The preparation of Radix Astragali extractive solution:Added after the Radix Astragali is crushed in 9 times of water, 0.8h is boiled in heating, filter, be concentrated to give Radix Astragali extractive solution.
(3)The preparation of agate card extract solution:Added after agate card is crushed in 9 times of water, 0.8h is boiled in heating, filter, be concentrated to give Agate card extract solution.
(4)The preparation of fructus lycii extracted solution:Added after agate card is crushed in 9 times of water, 0.8h is boiled in heating, filter, be concentrated to give Fructus lycii extracted solution.
(5)By step(1)-(4)Obtained pearl liquor 100g, Radix Astragali extractive solution 37g, agate card extract solution 22g, matrimony vine are extracted Liquid 15g mixes 20min;
(6)By step(5)Obtained mixed liquor carries out ultraviolet-sterilization, produces.
Embodiment 3
A kind of preparation method of anti-aging pearl oral liquid, comprises the following steps:
(1)The preparation of pearl liquor:Pearl weight 3-5% protease, regulation pH value to 4-4.5, heating will be added after crushing pearl 4h is stirred to 43 DEG C, suction filtration adds activated carbon, carries out secondary suction filtration, is heated to 65 DEG C of holding 1.5h, Temperature fall is obtained Pearl liquor.
(2)The preparation of Radix Astragali extractive solution:Added after the Radix Astragali is crushed in 10 times of water, 1h is boiled in heating, filter, be concentrated to give Huang Stilbene extract solution.
(3)The preparation of agate card extract solution:Added after agate card is crushed in 10 times of water, 1h is boiled in heating, filter, be concentrated to give agate Card extract solution.
(4)The preparation of fructus lycii extracted solution:Added after agate card is crushed in 10 times of water, 1h is boiled in heating, filter, be concentrated to give Chinese holly Qi extract solution.
(5)By step(1)-(4)Obtained pearl liquor 100g, Radix Astragali extractive solution 40g, agate card extract solution 22g, matrimony vine are extracted Liquid 16g mixes 20min;
(6)By step(5)Obtained mixed liquor carries out ultraviolet-sterilization, produces.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, although with reference to foregoing reality Apply example the present invention is described in detail, for those skilled in the art, it still can be to foregoing each implementation Technical scheme described in example is modified, or carries out equivalent substitution to which part technical characteristic.All essences in the present invention God is with principle, and any modification, equivalent substitution and improvements made etc. should be included in the scope of the protection.

Claims (7)

1. a kind of anti-aging pearl oral liquid, it is characterised in that the oral liquid is extracted by pearl liquor, Radix Astragali extractive solution, agate card Liquid, fructus lycii extracted solution are made, on the basis of the weight of pearl liquor, and Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution are accounted for respectively 35-40%, 18-22%, 12-16% of pearl liquor.
2. anti-aging pearl oral liquid according to claim 1, it is characterised in that Radix Astragali extractive solution in the oral liquid, Agate card extract solution, fructus lycii extracted solution account for 37%, 22%, the 15% of pearl liquor weight respectively.
3. anti-aging pearl oral liquid according to claim 1 or 2, it is characterised in that the pearl liquor is enzymolysis pearl Liquid.
4. the preparation method of the anti-aging pearl oral liquid described in claim any one of 1-3, it is characterised in that including following step Suddenly:
(1)The preparation of pearl liquor:Protease will be added after crushing pearl, pH value is adjusted, is heated to 40-43 DEG C and is stirred 4- 5h, suction filtration adds activated carbon, carries out secondary suction filtration, is heated to 60-65 DEG C of holding 1.5-2h, and Temperature fall obtains pearl liquor;
(2)The preparation of Radix Astragali extractive solution:Added after the Radix Astragali is crushed in 8-10 times of water, 0.5-1h is boiled in heating, filter, be concentrated to give Radix Astragali extractive solution;
(3)The preparation of agate card extract solution:Added after agate card is crushed in 8-10 times of water, 0.5-1h is boiled in heating, filter, be concentrated to give Agate card extract solution;
(4)The preparation of fructus lycii extracted solution:Added after agate card is crushed in 8-10 times of water, 0.5-1h is boiled in heating, filter, be concentrated to give Fructus lycii extracted solution;
(5)By step(1)-(4)Obtained pearl liquor, Radix Astragali extractive solution, agate card extract solution, fructus lycii extracted solution is mixed;
(6)By step(5)Obtained mixed liquor is sterilized, and is produced.
5. the preparation method of anti-aging pearl oral liquid according to claim 4, it is characterised in that the step(1)In, PH value regulated value 4-4.5.
6. the preparation method of anti-aging pearl oral liquid according to claim 4, it is characterised in that the step(4)In, The time of mixing is 20-30min.
7. the preparation method of anti-aging pearl oral liquid according to claim 4, it is characterised in that the step(5)In, Method for disinfection uses ultraviolet-sterilization.
CN201710185905.4A 2017-03-24 2017-03-24 A kind of anti-aging pearl oral liquid and preparation method thereof Pending CN107007690A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107811299A (en) * 2017-10-10 2018-03-20 林翠霞 A kind of female health food and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1080177A (en) * 1993-03-13 1994-01-05 武汉蓝天生物技术公司 Pearl wolfberry fruit syrup and preparation method thereof
CN100998858A (en) * 2007-01-07 2007-07-18 蔡绪旺 Chinese medicinal health-care preparation for face beaulifying and nourishing, anti-oxidation
CN101357139A (en) * 2007-08-03 2009-02-04 杨品红 Multivitamin selenium-enriched active pearl oral preparation and preparation method thereof
CN105998732A (en) * 2016-06-27 2016-10-12 青岛铭晨信息技术有限公司 Anti-aging Chinese herb healthcare oral liquid and preparation method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1080177A (en) * 1993-03-13 1994-01-05 武汉蓝天生物技术公司 Pearl wolfberry fruit syrup and preparation method thereof
CN100998858A (en) * 2007-01-07 2007-07-18 蔡绪旺 Chinese medicinal health-care preparation for face beaulifying and nourishing, anti-oxidation
CN101357139A (en) * 2007-08-03 2009-02-04 杨品红 Multivitamin selenium-enriched active pearl oral preparation and preparation method thereof
CN105998732A (en) * 2016-06-27 2016-10-12 青岛铭晨信息技术有限公司 Anti-aging Chinese herb healthcare oral liquid and preparation method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107811299A (en) * 2017-10-10 2018-03-20 林翠霞 A kind of female health food and preparation method thereof

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Application publication date: 20170804

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