CN107007519A - A kind of antibacterial bath oil - Google Patents

A kind of antibacterial bath oil Download PDF

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Publication number
CN107007519A
CN107007519A CN201710219804.4A CN201710219804A CN107007519A CN 107007519 A CN107007519 A CN 107007519A CN 201710219804 A CN201710219804 A CN 201710219804A CN 107007519 A CN107007519 A CN 107007519A
Authority
CN
China
Prior art keywords
extract
fructus
bath oil
rosae laevigatae
antibacterial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710219804.4A
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Chinese (zh)
Inventor
不公告发明人
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Poly Green Chemical Technology Research Institute Co Ltd
Original Assignee
Guangzhou Poly Green Chemical Technology Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Poly Green Chemical Technology Research Institute Co Ltd filed Critical Guangzhou Poly Green Chemical Technology Research Institute Co Ltd
Priority to CN201710219804.4A priority Critical patent/CN107007519A/en
Publication of CN107007519A publication Critical patent/CN107007519A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/81Preparation or application process involves irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/82Preparation or application process involves sonication or ultrasonication

Abstract

The present invention discloses a kind of antibacterial bath oil, including the plant composition that mass percent is 0.8~2.5%, plant composition is maiden cane extract, the mixture of Fructus Fructus Rosae Laevigatae extract and Herba polygoni hydropiperis extract, the weight part ratio of maiden cane extract, Fructus Fructus Rosae Laevigatae extract and Herba polygoni hydropiperis extract is (5~10):(2~6):(3~9).Flavone aglycone and flavonoid glycoside composition in antibacterial bath oil of the present invention in maiden cane extract, the Fructus Rosae Laevigatae polysaccharides in compounding Fructus Fructus Rosae Laevigatae extract and fruit of Cherokee rose volatile oil, compounding Herba polygoni hydropiperis extract, Synergistic, antibacterial bath oil of the present invention not only has the effect of good anti-inflammation, also with certain senile-resistant efficacy.

Description

A kind of antibacterial bath oil
Technical field
The present invention relates to household chemicals field, and in particular to a kind of antibacterial bath oil.
Background technology
Bath oil, a kind of liquid ceanser used when being and having a bath.It is excellent that bath oil is not stimulated gently because of it, fragrance is pleasant etc. Point, is generally used when having a bath by people, gradually instead of perfumed soap.Because bath oil is liquid, various functions can be conveniently added Property ingredient, however as the development of society, the pollution of environment is increasingly severe, and the particulate in air is attached to skin surface, Pruitus is easily caused, or even causes allergy, current bath oil is only to play a part of cleaning mostly, but skin Not only need cleaning, in addition it is also necessary to nutrient, the missing of skin nutrient, it is easy to cause the antibacterial action of skin itself to decline, at present Bath oil on the market can not meet the demand in daily life, therefore be badly in need of a kind of shower for being capable of effective anti-bacterial, anti-itching of exploitation Breast.
The content of the invention
Based on this, it is an object of the invention to provide a kind of antibacterial bath oil with antibiotic effect.
In order to achieve the above object, the present invention provides following technical scheme:
A kind of antibacterial bath oil includes the plant composition that mass percent is 0.8~2.5%, and plant composition is maiden cane The mixture of extract, Fructus Fructus Rosae Laevigatae extract and Herba polygoni hydropiperis extract, maiden cane extract, Fructus Fructus Rosae Laevigatae extract and polygonum flaccidum are extracted The weight part ratio of thing is (5~10):(2~6):(3~9).
The preparation method of the maiden cane extract is:Maiden cane is dried, 40~60 mesh sieves were crushed, 70~90% second are added Alcohol is after 30~60min of ultrasonic wave extraction, and 3000r/min centrifuges 10~30min, takes supernatant, and filter residue repeats said extracted step Suddenly, supernatant is merged, rotation is evaporated.
The preparation method of the Fructus Fructus Rosae Laevigatae extract comprises the following steps:
(1) dry Fructus Fructus Rosae Laevigatae was crushed into 40~60 mesh sieves, petroleum ether (60~90 DEG C) is used in apparatus,Soxhlet's Water-bath backflow degreasing 2 times, each 2h discards petroleum ether extract;
(2) Fructus Fructus Rosae Laevigatae powder is volatilized after petroleum ether, adds 70~90% ethanol, refluxing extraction 2 in microwave reactor ~3 times, 30~60min, collects extract solution every time, and rotated evaporimeter removes ethanol.
The preparation method of the Herba polygoni hydropiperis extract is:Polygonum flaccidum is cleaned into drying, 40~60 mesh sieves were crushed, plus 50~70% Ethanol, by solid-liquid ratio 1:(25~45), 40~60 DEG C of progress 40~60min of ultrasonic wave extraction, collect extract solution, rotated evaporation Instrument is concentrated.
Antibacterial bath oil of the present invention is made up of the component of following mass percent:
Make following introduce to the part material in antibacterial bath oil of the present invention:
Maiden cane extract:Maiden cane is one kind in grass family Panicum, and also known as broomcorn millet, millet, standing grain are held a memorial ceremony for and rotten, and annual herb is planted Thing.It originates from Chinese Huanghe valley Loess Plateau, and the plantation money of very abundant is formd in very long agro-farming history Source.Maiden cane extract has very strong antioxidant activity in vitro.
Fructus Fructus Rosae Laevigatae extract:Fructus Fructus Rosae Laevigatae extract is rich in Fructus Rosae Laevigatae polysaccharides, and Fructus Rosae Laevigatae polysaccharides are to Escherichia coli, secondary wound Cold bacillus, White staphylococcus and staphylococcus aureus etc. have very strong inhibitory action, and to saccharomyces cerevisiae and actinomyces There is stronger inhibitory action;Fruit of Cherokee rose volatile oil in Fructus Fructus Rosae Laevigatae extract has stronger removing O2-Ability.
Herba polygoni hydropiperis extract:Flavone aglycone and flavonoid glycoside composition have good antioxidation in Herba polygoni hydropiperis extract, and And Herba polygoni hydropiperis extract has the bacteriostasis of wide spectrum.
Compared with prior art, the method have the advantages that
(1) Fructus Rosae Laevigatae polysaccharides and gold in antibacterial bath oil of the present invention in maiden cane extract, compounding Fructus Fructus Rosae Laevigatae extract Flavone aglycone and flavonoid glycoside composition in cherry volatile oil, compounding Herba polygoni hydropiperis extract, Synergistic, antibacterial bath oil of the present invention Not only there is the effect of good anti-inflammation, also with certain senile-resistant efficacy.
(2) antibacterial bath oil of the present invention, green safety is gentle non-stimulated.
Embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.The antibacterial body wash formula of the present invention of embodiment 1~5 It is shown in Table one
Table one
The preparation method of maiden cane extract is described in embodiment 1~5:Maiden cane is dried, 60 mesh sieves were crushed, added 90% ethanol is after ultrasonic wave extraction 60min, and 3000r/min centrifugation 30min take supernatant, filter residue repeats said extracted step, Merge supernatant, rotation is evaporated.
The preparation method of Fructus Fructus Rosae Laevigatae extract comprises the following steps described in embodiment 1~5:
Dry Fructus Fructus Rosae Laevigatae was crushed into 60 mesh sieves, with 90 DEG C of water-bath backflow degreasings 2 of petroleum ether in apparatus,Soxhlet's Secondary, each 2h discards petroleum ether extract;
Fructus Fructus Rosae Laevigatae powder is volatilized after petroleum ether, 90% ethanol of addition, refluxing extraction 3 times in microwave reactor, every time 60min, collects extract solution, and rotated evaporimeter removes ethanol.
The preparation method of Herba polygoni hydropiperis extract is described in embodiment 1~5:Polygonum flaccidum is cleaned into drying, 60 mesh sieves were crushed, plus 50% ethanol, by solid-liquid ratio 1:45th, 60 DEG C of progress ultrasonic wave extraction 40min, collect extract solution, and rotated evaporimeter concentration is Can.
Comparative example 1
Difference with embodiment 1 is not add maiden cane extract, and other preparation conditions and method are same as Example 1.
Comparative example 2
Difference with embodiment 1 is not add Fructus Fructus Rosae Laevigatae extract, other preparation conditions and method and the phase of embodiment 1 Together.
Comparative example 3
Difference with embodiment 1 is not add Herba polygoni hydropiperis extract, and other preparation conditions and method are same as Example 1.
Comparative example 4
Difference with embodiment 1 is to add 0.7 part of plant composition, and other preparation conditions and method are same as Example 1.
Comparative example 5
Difference with embodiment 1 is to add 2.6 parts of plant composition, and other preparation conditions and method are same as Example 1.
Comparative example 6
Difference with embodiment 1 is not add plant composition, and other preparation conditions and method are same as Example 1.
Fungistatic effect is verified
The pre- culture medium 0.5ml for first passing through sterilization treatment is put into 96 hole microplates, above-described embodiment 1 is added respectively, it is right Ratio 1~6, the commercially available antibacterial bath oil claimed with good result does control group, using in culture medium ultimate density as 156ppm, 312ppm, 625ppm, 1250ppm, 2500ppm mode periodically dilute and prepare sample solution.To these sample solutions Middle addition about 1 × 106CFU/ml Escherichia coli A, Staphylococcus aureus B each nutrient solution 0.1ml, under aerobic conditions, Cultivated 4 days at 30 DEG C.Antibacterial effect is judged by visual observation, compared with the trial zone for being not added with mentioned microorganism, will not found micro- Muddy trial zone is considered as with antibacterial effect caused by biology propagation, determine for suppress needed for growth least concentration (with It is referred to as " minimum growth inhibitory concentration " down).As a result it is shown in table two
Table two
From the result of table two, antibacterial bath oil of the present invention is compared with as vs comparative examples and control group, to large intestine Bacillus and Staphylococcus aureus show equal extent or the antibacterial activity more than it.Prove that plant component has association in the present invention Same synergistic function, it uses composition interval optimal.
In a word, presently preferred embodiments of the present invention, all equalizations made according to scope of the present invention patent be the foregoing is only Change and modification, should all belong to the covering scope of patent of the present invention.

Claims (6)

1. a kind of antibacterial bath oil, it is characterised in that the bath oil includes the plant group that mass percent is 0.8~2.5% Compound;
Wherein, plant composition is the mixture of maiden cane extract, Fructus Fructus Rosae Laevigatae extract and Herba polygoni hydropiperis extract.
2. a kind of antibacterial bath oil according to claim 1, it is characterised in that the maiden cane extract, Fructus Fructus Rosae Laevigatae is carried The weight part ratio for taking thing and Herba polygoni hydropiperis extract is (5~10):(2~6):(3~9).
3. a kind of antibacterial bath oil according to claim 1 or 2, it is characterised in that the preparation side of the maiden cane extract Method is:Maiden cane is dried, 40~60 mesh sieves were crushed, 70~90% ethanol are added after 30~60min of ultrasonic wave extraction, 3000r/min centrifuges 10~30min, takes supernatant, and filter residue repeats said extracted step, merges supernatant, and rotation is evaporated.
4. a kind of antibacterial bath oil according to claim 1 or 2, it is characterised in that the system of the Fructus Fructus Rosae Laevigatae extract Preparation Method comprises the following steps:
(1) dry Fructus Fructus Rosae Laevigatae was crushed into 40~60 mesh sieves, petroleum ether (60~90 DEG C) water-bath is used in apparatus,Soxhlet's Flow back degreasing 2 times, and each 2h discards petroleum ether extract;
(2) Fructus Fructus Rosae Laevigatae powder is volatilized after petroleum ether, adds 70~90% ethanol, refluxing extraction 2~3 in microwave reactor Secondary, 30~60min, collects extract solution every time, and rotated evaporimeter removes ethanol.
5. a kind of antibacterial bath oil according to claim 1 or 2, it is characterised in that the preparation side of the Herba polygoni hydropiperis extract Method is:Polygonum flaccidum is cleaned into drying, 40~60 mesh sieves were crushed, plus 50~70% ethanol, by solid-liquid ratio 1:(25~45), 40~60 DEG C 40~60min of ultrasonic wave extraction is carried out, collect extract solution, the concentration of rotated evaporimeter.
6. a kind of antibacterial bath oil according to claim 1, it is characterised in that the bath oil is by following mass percent Component composition:
CN201710219804.4A 2017-04-05 2017-04-05 A kind of antibacterial bath oil Pending CN107007519A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710219804.4A CN107007519A (en) 2017-04-05 2017-04-05 A kind of antibacterial bath oil

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710219804.4A CN107007519A (en) 2017-04-05 2017-04-05 A kind of antibacterial bath oil

Publications (1)

Publication Number Publication Date
CN107007519A true CN107007519A (en) 2017-08-04

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Country Status (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108578314A (en) * 2018-05-28 2018-09-28 浙江艾卡医学科技有限公司 A kind of composition containing plant extracts and its application in except mite nursing product
CN109157447A (en) * 2018-09-25 2019-01-08 任旻琼 Application and preparation method of the Fructus Rosae Laevigatae extract in skin whitening, moisturizing anti-aging skin care product

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108578314A (en) * 2018-05-28 2018-09-28 浙江艾卡医学科技有限公司 A kind of composition containing plant extracts and its application in except mite nursing product
CN109157447A (en) * 2018-09-25 2019-01-08 任旻琼 Application and preparation method of the Fructus Rosae Laevigatae extract in skin whitening, moisturizing anti-aging skin care product
CN109157447B (en) * 2018-09-25 2021-10-26 任旻琼 Application of cherokee rose fruit extract in whitening, moisturizing and anti-aging skin care product and preparation method thereof

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Application publication date: 20170804

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