CN107007516A - A kind of antiallergic prescription containing plant extracts - Google Patents
A kind of antiallergic prescription containing plant extracts Download PDFInfo
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- CN107007516A CN107007516A CN201611260509.5A CN201611260509A CN107007516A CN 107007516 A CN107007516 A CN 107007516A CN 201611260509 A CN201611260509 A CN 201611260509A CN 107007516 A CN107007516 A CN 107007516A
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- plant extracts
- prescription
- antiallergic
- allergic
- mixtures
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Biotechnology (AREA)
- Botany (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to the antiallergic prescription of a kind of skin care item prescription, particularly a Plant Extracts, belong to daily chemical product technical field.Using plant extracts as core functional component in the prescription, other auxiliary elements are equipped with.This prescription contains each component with following percentage by weight:Gotu Kola P.E, oat(Naked oats)One or more in extract, licorice, burdock extract, radix paeoniae alba extraction etc., total content is 0.1 ~ 10.0%, auxiliary element 90.0% ~ 99.9%, and auxiliary element is mainly included:Lipid 5 ~ 10%, oils 5% ~ 10%, senior class fatty alcohols 1% ~ 5%, emulsifying agent 1% ~ 10%, preservative 0.1% ~ 1.0%, essence 0.1% ~ 1.0%, remaining is deionized water.The present invention has remarkable efficacy, moreover it is possible to prevent and allergic problem of releiving, effect is notable from allergic, itch and the mechanism of production of inflammation to allergic and inflammation.
Description
Technical field
The present invention relates to a kind of antiallergic skin care item prescription, and in particular to a kind of antiallergic prescription containing plant extracts, belongs to
Daily chemical product technical field.
Background technology
Anaphylaxis(Or hyperirritability)Skin is the common phenomenon in crowd.Epidemiological study points out have in Britain
51.4% women and 38.2% male, there is allergic experience.Equally, find have in the phone investigation in the U.S.
It oneself is sensitive that 52% women, which is claimed,.In addition, pointing out 52% participant in an epidemiological study of France
It is sensitive, and women(59%)It is significantly higher than male(44%).As can be seen here, the incidence of allergic skin is very high,
Through becoming a global problem.And allergic skin has had a strong impact on the life of patient, especially bring greatly
Psychiatric disturbance.In addition, the clinical sign of allergic skin can also occur for normal skin, it is damaged with its skin barrier function relevant;
Dermopathic a part of clinical sign, such as allergic dermatitis, brandy nose and psoriasis can also be used as simultaneously.
Outstanding anti-anaphylaxis cosmetics can not only high-efficient cleaning remove free radical, and cell membrane can be protected not encroached on by free radical,
Sensitizing factor can also be suppressed --- the release of histamine, cell can be goed deep into and fundamentally block anaphylactoid generation.
The content of the invention
The present invention relates to the antiallergic prescription of a kind of skin care item prescription, particularly a Plant Extracts, belong to daily-use chemical industry
Product technical field.Using plant extracts as core functional component in the prescription, other auxiliary elements are equipped with.The present invention is from skin
The mechanism of production of skin allergy, itch and inflammation is set out, and has significant curative effect to allergic and inflammation, moreover it is possible to prevent and relax
Delay allergic problem, effect is notable.
In order to solve the above problems, the technical solution adopted in the present invention is:
The antiallergic prescription of one Plant Extracts, using plant extracts as core functional component, is equipped with other auxiliary elements.This group
Side contains each component with following percentage by weight:0.1 ~ 10.0%. of plant extracts, auxiliary element accounts for 90.0% ~
99.9%。
Plant extracts in the prescription includes following one or more:Gotu Kola P.E, oat(Naked oats)Extract
Thing, licorice, burdock extract, radix paeoniae alba extraction etc..
The auxiliary element of the prescription mainly includes following material:
(1)Esters 5 ~ 10%, for selected from caprylic/capric triglyceride, isopropyl myristate, pentaerythritol stearic acid ester 2, palm fibre
One or more mixtures in palmitic acid acid ethylhexyl, isononyl isononanoate, tridecanol trimellitate;
(2)Oils 5% ~ 10%, for one in camellia seed oil, the alkane of C15 ~ 19, Butyrospermum parkii fruit oil and dimethyl silicone polymer
Plant or a variety of mixtures;
(3)Senior class fatty alcohols 1% ~ 5%, for one in cetanol, stearyl alcohol, cetostearyl alcohol, isooctadecanol, docosyl alcohol
Plant or a variety of mixtures;
(4)Emulsifying agent 1% ~ 10%, for selected from tetraethylene glycol monolaurate, alkylaryl sulfonates, polyoxyethylene mono laurate
One or more mixtures in ester;
(5)Remaining is aqueous carrier, includes the one or more in preservative, essence.
A kind of described antiallergic prescription containing plant extracts, is prepared according to following steps:
Plant extracts 0.1 ~ 10.0% is taken by prescription quality percentage, and auxiliary element 90.0 ~ 99.9%, including esters 5 ~ 10%,
For selected from caprylic/capric triglyceride, isopropyl myristate, pentaerythritol stearic acid ester 2, ethylhexyl palmitate, different nonyl
One or more mixtures in the different nonyl ester of acid, tridecanol trimellitate;Oils 5% ~ 10%, for selected from camellia seed oil, C15
One or more mixtures in ~ 19 alkane, Butyrospermum parkii fruit oil and dimethyl silicone polymer;Senior class fatty alcohols 1% ~ 5%, for choosing
From one or more mixtures in cetanol, stearyl alcohol, cetostearyl alcohol, isooctadecanol, docosyl alcohol;Emulsifying agent 1% ~ 10%,
For the one or more mixing in tetraethylene glycol monolaurate, alkylaryl sulfonates, Vinlub 73
Thing;Remaining is aqueous carrier, includes the one or more in preservative, essence.It is well mixed, produce a Plant Extracts
Antiallergic prescription.
The beneficial effects of the invention are as follows:Contain the Triterpenoid of a variety of α-botany bar gum alcohol type in Gotu Kola P.E, have
Calm, stable effect, calm skin can be helped by being added in skin care item, alleviate sensitivity phenomenon.Contain oat in oat extract
The compositions such as peptide, avenabeta glucosan, oat oil, there is the work(such as skin whitening, moisturizing, increase skin activity, delaying skin aging, antiallergy
Effect.In addition, oat also has itching-relieving action.Oat has very strong adsorptivity, can effectively remove the dirt of deep skin, play
Antipruritic effect;Contain a variety of nutritional ingredients to skin beneficiating in oat, such as amino acid, which has, to be pinned moisture of skin, keeps
The effect of skin wet.This has good effect to preventing and treating the itch because of caused by dry skin.Licorice have anti-inflammatory and
The effect of antiallergic action, granuloma induced by implantation of cotton pellets of the enoxolone to big white mouse, formaldehyde edema, tuberculin reaction, subcutaneous meat
Bud capsule inflammation has inhibitory action.What ammonium glycyrrhetate, Sodium glycyrrhetinate can effectively influence subcutaneous granulation capsule inflammation oozes out the phase
And proliferative phase, its action intensity is weaker than or close to cortisone.Active component in burdock extract is released inflammatory factor
Put inhibited, wherein arctigenin can significantly inhibit the mouse macrophage of lipopolysaccharides (LPS) induction to TNF-α
Release, it may be possible to include TNF-α, NO generations and lymphocyte to activated macrophage, lymphocyte by adjusting immune response
Propagation plays antiinflammatory action.The excessive swelling of the rat foot claw of white peony root's total glycoside Carrageenan induction in radix paeoniae alba extraction has
Obvious inhibiting effect, has obvious preventive and therapeutic effect to rat polyarthirtis.Its mechanism of action may suppress scorching with white peony root's total glycoside
Disease part pro-inflammatory cytokine, such as PGE, leukotriene (LTB) synthesis is relevant.White peony root's total glycoside can also lower the generation of its mononuclear macrophage
Excessive NO.The inhibitory action that white peony root's total glycoside is secreted to NO may be relevant with its anti-inflammatory mechanisms.The present invention is to allergic and inflammation
Disease has significant curative effect, moreover it is possible to prevent and allergic problem of releiving, effect is notable.
Embodiment
The present invention is described in further details below by embodiment, these embodiments are only used for illustrating the present invention, and
Do not limit the scope of the invention.
Embodiment 1
By formulation weight percentage extracting liquorice extract 0.5%, Gotu Kola P.E, oat(Naked oats)Extract, great burdock achene are extracted
Thing, radix paeoniae alba extraction each 0.5%, and auxiliary element 97.5%, including esters 5.0%, for selected from caprylic/capric triglyceride, Pork and beans
Cool isopropyl propionate, pentaerythritol stearic acid ester 2, ethylhexyl palmitate, isononyl isononanoate, tridecanol trimellitate
In one or more mixtures;Oils 5.0%, for selected from camellia seed oil, the alkane of C15 ~ 19, Butyrospermum parkii fruit oil and poly dimethyl
One or more mixtures in siloxanes;Senior class fatty alcohols 3.0%, for selected from cetanol, stearyl alcohol, cetostearyl alcohol, different
One or more mixtures in stearyl alcohol, docosyl alcohol;Emulsifying agent 5.0%, for selected from tetraethylene glycol monolaurate, alkyl virtue
One or more mixtures in base sulfonate, Vinlub 73;Remaining is aqueous carrier, include preservative,
One or more in essence.It is well mixed, produce the antiallergic skin care item of a Plant Extracts.
Embodiment 2
By formulation weight percentage extracting liquorice extract 1.0%, Gotu Kola P.E, oat(Naked oats)Extract, great burdock achene are extracted
Thing, radix paeoniae alba extraction each 0.5%, and auxiliary element 97.0%, including esters 5.0%, for selected from caprylic/capric triglyceride, Pork and beans
Cool isopropyl propionate, pentaerythritol stearic acid ester 2, ethylhexyl palmitate, isononyl isononanoate, tridecanol trimellitate
In one or more mixtures;Oils 5.0%, for selected from camellia seed oil, the alkane of C15 ~ 19, Butyrospermum parkii fruit oil and poly dimethyl
One or more mixtures in siloxanes;Senior class fatty alcohols 3.0%, for selected from cetanol, stearyl alcohol, cetostearyl alcohol, different
One or more mixtures in stearyl alcohol, docosyl alcohol;Emulsifying agent 5.0%, for selected from tetraethylene glycol monolaurate, alkyl virtue
One or more mixtures in base sulfonate, Vinlub 73;Remaining is aqueous carrier, include preservative,
One or more in essence.It is well mixed, produce the antiallergic skin care item of a Plant Extracts.
Embodiment 3
By formulation weight percentage extracting liquorice extract 2.0%, Gotu Kola P.E, oat(Naked oats)Extract, great burdock achene are extracted
Thing, radix paeoniae alba extraction each 0.5%, and auxiliary element 96.0%, including esters 5.0%, for selected from caprylic/capric triglyceride, Pork and beans
Cool isopropyl propionate, pentaerythritol stearic acid ester 2, ethylhexyl palmitate, isononyl isononanoate, tridecanol trimellitate
In one or more mixtures;Oils 5.0%, for selected from camellia seed oil, the alkane of C15 ~ 19, Butyrospermum parkii fruit oil and poly dimethyl
One or more mixtures in siloxanes;Senior class fatty alcohols 3.0%, for selected from cetanol, stearyl alcohol, cetostearyl alcohol, different
One or more mixtures in stearyl alcohol, docosyl alcohol;Emulsifying agent 5.0%, for selected from tetraethylene glycol monolaurate, alkyl virtue
One or more mixtures in base sulfonate, Vinlub 73;Remaining is aqueous carrier, include preservative,
One or more in essence.It is well mixed, produce the antiallergic skin care item of a Plant Extracts.
Embodiment 4
By formulation weight percentage extracting liquorice extract 3.0%, Gotu Kola P.E, oat(Naked oats)Extract, great burdock achene are extracted
Thing, radix paeoniae alba extraction each 0.5%, and auxiliary element 95.0%, including esters 5.0%, for selected from caprylic/capric triglyceride, Pork and beans
Cool isopropyl propionate, pentaerythritol stearic acid ester 2, ethylhexyl palmitate, isononyl isononanoate, tridecanol trimellitate
In one or more mixtures;Oils 5.0%, for selected from camellia seed oil, the alkane of C15 ~ 19, Butyrospermum parkii fruit oil and poly dimethyl
One or more mixtures in siloxanes;Senior class fatty alcohols 3.0%, for selected from cetanol, stearyl alcohol, cetostearyl alcohol, different
One or more mixtures in stearyl alcohol, docosyl alcohol;Emulsifying agent 5.0%, for selected from tetraethylene glycol monolaurate, alkyl virtue
One or more mixtures in base sulfonate, Vinlub 73;Remaining is aqueous carrier, include preservative,
One or more in essence.It is well mixed, produce the antiallergic skin care item of a Plant Extracts.
Embodiment 5
The clinical observation material of prescription application antiallergic of the present invention.
(1)Clinical manifestation:Allergic dermatitis(allergic dermatitis)It is the skin disease as caused by anaphylactogen, it is main
Refer to human contact cause to some anaphylactogens red swelling of the skin, itch, wheal, the skin disorder such as decortication.Specific allergy
Original can be divided into contact allergy original, suck anaphylactogen, eats anaphylactogen and be injected into the class of anaphylactogen four.Can per class anaphylactogen
Cause corresponding allergic reaction, main performance is diversified dermatitis, eczema, nettle rash.Allergic dermatitis is by many
Scytitis reacts caused by factor.Allergic reaction caused by different pathogenic factors is different.The Symptoms of allergic dermatitis are
Skin can become extreme itch, scratch and grab affected part and can cause red swelling of the skin, cracking, leach transparent liquid, it is last be even hardened, furfur.
(2)Treatment method:From antiallergic prescription of the above-described embodiment 4 containing plant extracts, according to allergic, itch,
The degree selection of inflammation is slight, moderate, severe patient totally 60 people, he the skin care item 2 times of the prescription is smeared daily, after smearing 1 month
Stop smearing, the order of severity and pruitus number of times of inflammation are observed two days later.
(3)Efficacy assessment standard
It is effective:Symptom disappears, and skin condition recovers normal, and observation half a year is without recidivist;
Take a turn for the better:Symptom is clearly better, and skin condition progressively recovers;
It is invalid:Improvement standard person is not reached.
(1)Treatment results(It see the table below)
In above-mentioned treatment, allergic and inflammatory patients 60 are treated with composing prescription preparation of the present invention, patients with mild 20 shows
Effect 19, obvious effective rate 95.0%, effective percentage 100.0%;Moderate patient 20, effective number of cases 14, obvious effective rate 70.0%, improvement example
Number 5, improvement rate 25.0%, invalid number of cases 1, effective percentage 95.0%;Severe patient 20, effective number of cases 12, obvious effective rate
60.0%, improvement number of cases 7, improvement rate 35.0%, invalid number of cases 1;Effective number of cases 58, total effective rate 96.7%.
Claims (4)
1. the antiallergic prescription of a Plant Extracts, using plant extracts as core functional component, is equipped with other auxiliary elements;This
Prescription contains each component with following percentage by weight:0.1 ~ 10.0%. of plant extracts, auxiliary element accounts for 90.0%-
99.9%;
Plant extracts in the skin care item includes following one or more:Gotu Kola P.E, oat(Naked oats)Extract,
Licorice, burdock extract, radix paeoniae alba extraction etc..
2. a kind of antiallergic prescription containing plant extracts as claimed in claim 1, it is characterised in that auxiliary element is mainly included
Following material:
(1)Esters 5 ~ 10%, for selected from caprylic/capric triglyceride, isopropyl myristate, pentaerythritol stearic acid ester 2, palm fibre
One or more mixtures in palmitic acid acid ethylhexyl, isononyl isononanoate, tridecanol trimellitate;
(2)Oils 5% ~ 10%, for one in camellia seed oil, the alkane of C15 ~ 19, Butyrospermum parkii fruit oil and dimethyl silicone polymer
Plant or a variety of mixtures;
(3)Senior class fatty alcohols 1% ~ 5%, for one in cetanol, stearyl alcohol, cetostearyl alcohol, isooctadecanol, docosyl alcohol
Plant or a variety of mixtures;
(4)Emulsifying agent 1% ~ 10%, for selected from tetraethylene glycol monolaurate, alkylaryl sulfonates, polyoxyethylene mono laurate
One or more mixtures in ester;
(5)Remaining is aqueous carrier, includes the one or more in preservative, essence.
3. a kind of antiallergic prescription containing plant extracts according to claim 1, it is characterised in that:It includes following step
Suddenly:Plant extracts 0.1 ~ 10.0% is taken by formulation weight percentage, with auxiliary element 90.0 ~ 99.9%, is well mixed, produces one
Plant the antiallergic skin care item containing plant extracts.
4. a kind of antiallergic prescription containing plant extracts according to claim 1, in skin type daily chemical product
Using, it is characterised in that the present invention has from allergic, itch and the mechanism of production of inflammation to allergic and inflammation
Significant curative effect, moreover it is possible to prevent and allergic problem of releiving, effect is notable;The content of plant extracts should not in prescription
Less than 0.1%, not higher than 10.0%.
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CN201611260509.5A CN107007516A (en) | 2016-12-30 | 2016-12-30 | A kind of antiallergic prescription containing plant extracts |
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CN201611260509.5A CN107007516A (en) | 2016-12-30 | 2016-12-30 | A kind of antiallergic prescription containing plant extracts |
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Cited By (2)
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WO2019236935A1 (en) * | 2018-06-08 | 2019-12-12 | The Procter & Gamble Company | Topical skincare compositions comprising centella asiatica selected triterpenes |
WO2022222215A1 (en) * | 2021-04-23 | 2022-10-27 | 施政宏 | Skin care composite essence oil |
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CN102370761A (en) * | 2010-08-18 | 2012-03-14 | 上海科鑫生物工程有限公司 | Traditional Chinese medicine compound recipe used for preventing or resisting allergy, preparation method thereof, and application thereof |
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2016
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CN102370761A (en) * | 2010-08-18 | 2012-03-14 | 上海科鑫生物工程有限公司 | Traditional Chinese medicine compound recipe used for preventing or resisting allergy, preparation method thereof, and application thereof |
CN103584093A (en) * | 2013-10-29 | 2014-02-19 | 无限极(中国)有限公司 | Application of white peony root extract in preparation of health food or cosmetic with anti-radiation and anti-aging effects |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019236935A1 (en) * | 2018-06-08 | 2019-12-12 | The Procter & Gamble Company | Topical skincare compositions comprising centella asiatica selected triterpenes |
US10980851B2 (en) | 2018-06-08 | 2021-04-20 | The Procter & Gamble Company | Topical skincare compositions comprising Centella asiatica selected triterpenes |
WO2022222215A1 (en) * | 2021-04-23 | 2022-10-27 | 施政宏 | Skin care composite essence oil |
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