CN106999515A - 含有亚铁胺基酸螯合物的组合物在制备调控脂肪代谢的药物的用途 - Google Patents

含有亚铁胺基酸螯合物的组合物在制备调控脂肪代谢的药物的用途 Download PDF

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CN106999515A
CN106999515A CN201480083710.3A CN201480083710A CN106999515A CN 106999515 A CN106999515 A CN 106999515A CN 201480083710 A CN201480083710 A CN 201480083710A CN 106999515 A CN106999515 A CN 106999515A
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amino acid
acid
composition
ferrous
chelate
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CN106999515B (zh
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林村源
詹勋锦
傅嘉慧
陈沧泽
陈木桂
李宏谟
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Profeat Biotechnology Co ltd
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Profeat Biotechnology Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

本发明提供一种含有亚铁胺基酸螯合物的组合物在制备调控脂肪代谢的药物的用途,其中药物包含有效调控脂肪代谢剂量的含有亚铁胺基酸螯合物的组合物以及其药学上可接受的载剂。本发明所述的含有亚铁胺基酸螯合物的组合物中,胺基酸可与亚铁维持螯合状态通过胃,且可有效控制受体的体重变化以及促进体脂肪分解;本发明所述的含有亚铁胺基酸螯合物的组合物制备而得的药物具有调控脂肪代谢的效果。

Description

PCT国内申请,说明书已公开。

Claims (10)

  1. PCT国内申请,权利要求书已公开。
CN201480083710.3A 2014-12-01 2014-12-01 含有亚铁胺基酸螯合物的组合物在制备调控脂肪代谢的药物的用途 Expired - Fee Related CN106999515B (zh)

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Application Number Priority Date Filing Date Title
PCT/CN2014/092688 WO2016086338A1 (zh) 2014-12-01 2014-12-01 含有亚铁胺基酸螯合物的组合物在制备调控脂肪代谢的药物的用途

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CN106999515A true CN106999515A (zh) 2017-08-01
CN106999515B CN106999515B (zh) 2020-10-02

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US (1) US10183040B2 (zh)
EP (1) EP3132798B1 (zh)
JP (1) JP6440843B2 (zh)
CN (1) CN106999515B (zh)
AU (1) AU2014413288B2 (zh)
CA (1) CA2969010C (zh)
WO (1) WO2016086338A1 (zh)

Families Citing this family (6)

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Publication number Priority date Publication date Assignee Title
US11110065B2 (en) * 2018-03-06 2021-09-07 Profeat Biotechnology Co., Ltd. Sintered ferrous amino acid particles and use of the same against a virus
US11141382B2 (en) 2018-03-06 2021-10-12 Profeat Biotechnology Co., Ltd. Sintered nanoparticles and use of the same against a virus
US10813906B2 (en) * 2018-04-13 2020-10-27 Profeat Biotechnology Co., Ltd. Use of ferrous amino acid chelate to treat infection by enteropathogen and to enhance growth performance
JP6999175B2 (ja) * 2018-07-31 2022-02-04 株式会社東洋新薬 経口組成物
CN112168842A (zh) * 2019-07-05 2021-01-05 普惠德生技股份有限公司 经烧结的粒子在治疗肠道感染以及提升生长性能上的用途
US20230012448A1 (en) 2021-06-30 2023-01-12 Getwing Biotechnology Medical Co., Ltd Methods for alleviating kidney disease and fibrosis of organ

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GB802565A (en) * 1957-03-26 1958-10-08 Schwarz Arzneimittelfabrik G M Ferrous sulphate-glycine complex
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US4599152A (en) * 1985-05-24 1986-07-08 Albion Laboratories Pure amino acid chelates
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WO2010050179A1 (ja) * 2008-10-27 2010-05-06 Sbiアラプロモ株式会社 5-アミノレブリン酸若しくはその誘導体、又はそれらの塩を有効成分とする成人病の予防・改善剤
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Also Published As

Publication number Publication date
EP3132798A4 (en) 2017-11-22
EP3132798A1 (en) 2017-02-22
EP3132798B1 (en) 2020-03-11
AU2014413288B2 (en) 2018-06-28
US20170224727A1 (en) 2017-08-10
CA2969010A1 (en) 2016-06-09
CA2969010C (en) 2020-01-28
CN106999515B (zh) 2020-10-02
JP6440843B2 (ja) 2018-12-19
WO2016086338A1 (zh) 2016-06-09
AU2014413288A1 (en) 2017-07-13
JP2018500297A (ja) 2018-01-11
US10183040B2 (en) 2019-01-22

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