CN106964062B - 片材的制造方法 - Google Patents
片材的制造方法 Download PDFInfo
- Publication number
- CN106964062B CN106964062B CN201610958649.3A CN201610958649A CN106964062B CN 106964062 B CN106964062 B CN 106964062B CN 201610958649 A CN201610958649 A CN 201610958649A CN 106964062 B CN106964062 B CN 106964062B
- Authority
- CN
- China
- Prior art keywords
- mold
- nozzle
- needle
- liquid
- filling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C31/00—Handling, e.g. feeding of the material to be shaped, storage of plastics material before moulding; Automation, i.e. automated handling lines in plastics processing plants, e.g. using manipulators or robots
- B29C31/04—Feeding of the material to be moulded, e.g. into a mould cavity
- B29C31/041—Feeding of the material to be moulded, e.g. into a mould cavity using filling or dispensing heads placed in closed moulds or in contact with mould walls
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/38—Moulds or cores; Details thereof or accessories therefor characterised by the material or the manufacturing process
- B29C33/3842—Manufacturing moulds, e.g. shaping the mould surface by machining
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/003—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor characterised by the choice of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/02—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
- B29C39/026—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles characterised by the shape of the surface
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/22—Component parts, details or accessories; Auxiliary operations
- B29C39/24—Feeding the material into the mould
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
- A61M2207/10—Device therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2005/00—Use of polysaccharides or derivatives as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2883/00—Use of polymers having silicon, with or without sulfur, nitrogen, oxygen, or carbon only, in the main chain, as mould material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/753—Medical equipment; Accessories therefor
- B29L2031/7544—Injection needles, syringes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/756—Microarticles, nanoarticles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mechanical Engineering (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Manufacturing & Machinery (AREA)
- Robotics (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015211803A JP6517126B2 (ja) | 2015-10-28 | 2015-10-28 | シートの製造方法 |
| JP2015-211803 | 2015-10-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106964062A CN106964062A (zh) | 2017-07-21 |
| CN106964062B true CN106964062B (zh) | 2020-11-03 |
Family
ID=57345679
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610958649.3A Expired - Fee Related CN106964062B (zh) | 2015-10-28 | 2016-10-28 | 片材的制造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10512765B2 (enExample) |
| EP (1) | EP3162526B1 (enExample) |
| JP (1) | JP6517126B2 (enExample) |
| KR (1) | KR20170049415A (enExample) |
| CN (1) | CN106964062B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111433001B (zh) * | 2017-12-05 | 2022-03-18 | 古河电气工业株式会社 | 功能性构件及其制造方法 |
| EP3777955B1 (en) * | 2018-03-30 | 2023-07-26 | FUJIFILM Corporation | Microneedle array manufacturing method |
| CN110625864A (zh) * | 2019-10-24 | 2019-12-31 | 上海微创生命科技有限公司 | 微针制备装置及微针制备方法 |
| CN111590932B (zh) * | 2020-06-03 | 2021-10-12 | 河南泰田重工机械制造有限公司 | 一种玻璃钢模压上料装置 |
| DE102020131229A1 (de) * | 2020-11-25 | 2022-05-25 | Novem Car Interior Design Gmbh | Verfahren zum Herstellen eines Formteils |
| TWI882229B (zh) * | 2021-06-01 | 2025-05-01 | 波蘭商Ｘｔｐｌ股份有限公司 | 用聚合物材料填充微腔的方法 |
| WO2025105919A1 (ko) * | 2023-11-13 | 2025-05-22 | 주식회사 주빅 | 마이크로 파티클 제조방법 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1246406A (zh) * | 1998-09-01 | 2000-03-08 | 住友重机械工业株式会社 | 注入成形装置的喷嘴接触装置 |
| CN101912663A (zh) * | 2010-08-18 | 2010-12-15 | 清华大学 | 空心微针阵列芯片、经皮给药贴片、器件及制备方法 |
| JP5236695B2 (ja) * | 2010-06-29 | 2013-07-17 | 株式会社日本製鋼所 | ノズルタッチ方法およびノズルタッチ装置 |
| CN104780967A (zh) * | 2012-11-13 | 2015-07-15 | 富士胶片株式会社 | 经皮吸收片的制造方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1274646A (en) * | 1968-07-26 | 1972-05-17 | Alexander Young Stirrat | Improvements in or relating to casing apparatus |
| US3718524A (en) * | 1970-08-28 | 1973-02-27 | E Bright | Apparatus for forming attachable incompletely-cured plastic wafers |
| US3679341A (en) * | 1970-09-25 | 1972-07-25 | Owens Illinois Inc | Apparatus for impact injection molding of plastic articles |
| CA1290526C (en) * | 1986-11-07 | 1991-10-15 | Marianne Wieser | Mold and die operation |
| JP4603869B2 (ja) * | 2004-12-15 | 2010-12-22 | フィーサ株式会社 | バルブノズル |
| DE102006004690A1 (de) * | 2006-01-31 | 2007-08-02 | Bühler AG | Verfahren und Vorrichtung zum Giessen von Verzehrprodukten |
| US7537445B2 (en) * | 2006-10-27 | 2009-05-26 | Trelleborg Sealing Solutions Us, Inc. | Injection molding assembly having a product remover with a biasing member |
| KR101030752B1 (ko) * | 2009-04-09 | 2011-04-26 | 한국생명공학연구원 | 유체전달을 조절할 수 있는 마이크로 니들 유닛 |
| JP5562882B2 (ja) * | 2011-02-18 | 2014-07-30 | 三菱重工業株式会社 | 鉄道車両 |
| CA2865376A1 (en) * | 2012-03-02 | 2013-09-06 | Sakura Seiki Co., Ltd. | Steam sterilizer |
-
2015
- 2015-10-28 JP JP2015211803A patent/JP6517126B2/ja not_active Expired - Fee Related
-
2016
- 2016-10-25 KR KR1020160139193A patent/KR20170049415A/ko not_active Withdrawn
- 2016-10-27 US US15/335,436 patent/US10512765B2/en not_active Expired - Fee Related
- 2016-10-27 EP EP16196140.4A patent/EP3162526B1/en not_active Not-in-force
- 2016-10-28 CN CN201610958649.3A patent/CN106964062B/zh not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1246406A (zh) * | 1998-09-01 | 2000-03-08 | 住友重机械工业株式会社 | 注入成形装置的喷嘴接触装置 |
| JP5236695B2 (ja) * | 2010-06-29 | 2013-07-17 | 株式会社日本製鋼所 | ノズルタッチ方法およびノズルタッチ装置 |
| CN101912663A (zh) * | 2010-08-18 | 2010-12-15 | 清华大学 | 空心微针阵列芯片、经皮给药贴片、器件及制备方法 |
| CN104780967A (zh) * | 2012-11-13 | 2015-07-15 | 富士胶片株式会社 | 经皮吸收片的制造方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US10512765B2 (en) | 2019-12-24 |
| US20170120026A1 (en) | 2017-05-04 |
| EP3162526B1 (en) | 2018-07-25 |
| EP3162526A1 (en) | 2017-05-03 |
| JP2017080084A (ja) | 2017-05-18 |
| JP6517126B2 (ja) | 2019-05-22 |
| CN106964062A (zh) | 2017-07-21 |
| KR20170049415A (ko) | 2017-05-10 |
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