CN106963839A - A kind of antipruritic liquid medicine - Google Patents

A kind of antipruritic liquid medicine Download PDF

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Publication number
CN106963839A
CN106963839A CN201710173696.1A CN201710173696A CN106963839A CN 106963839 A CN106963839 A CN 106963839A CN 201710173696 A CN201710173696 A CN 201710173696A CN 106963839 A CN106963839 A CN 106963839A
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China
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liquid medicine
antipruritic liquid
alcohol
leaf
raw material
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CN201710173696.1A
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Chinese (zh)
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黄镜清
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Individual
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Priority to CN201710173696.1A priority Critical patent/CN106963839A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of antipruritic liquid medicine, it is made up of the following raw material component by quality proportioning:400 ~ 550g of kuh-seng, 450 ~ 550g of Mozzie buster, enter 400 ~ 600g of earthworm, read 350 ~ 500g, 400 ~ 600g of ivy tree bark, spend 450 ~ 550g of amphibious crab grass, 500 ~ 550g of Fruticose Breyniae Leaf and Twig's leaf, 300 ~ 700g of 450 ~ 550g of shinyleaf pricklyash root root and alcohol in vain.Its preparation method be by quality proportioning weigh various medicinal materials in raw material it is well mixed after be together placed in glass container with alcohol through boiling or soak to liquid medicine quality is green, filter and remove residue takes filtrate.The present invention passes through the special selection to raw material components and ratio optimization, the mutual inhibition of compatibility, mutual restraint between two drugs, the choosing of the mutual-detoxication between raw medicinal material are evaded, make medicine mutual reinforcement between, mutually make effect notable, it can quick flat azaleine spot, relieving itching and eliminating swelling, its original effect is shown to its pruitus mainly triggered in vivo by wet poison, food hypersenstivity, drug allergy etc., and short treating period, curative effect are stable, have no toxic side effect.

Description

A kind of antipruritic liquid medicine
Technical field
The present invention relates to external Chinese medicinal liquor field, more particularly to a kind of antipruritic liquid medicine.
Background technology
With food pollution, air pollution it is increasingly serious, the incidence of disease of people's disease of skin also increases.Skin disease It is a kind of common disease, it is most of along with various pruritis, cause different degrees of pain and discomfort to patient.
On the market for skin it is antipruritic drug variety it is various, wherein for bacterium, fungal infection medicine drug effect more Significantly, it is but this by the disease of the skin surface itch triggered in vivo for such as wet poison, food hypersenstivity, drug allergy on the market Shape, but lacks the medicine of instant effect.
The content of the invention
It is an object of the invention to for above-mentioned the deficiencies in the prior art, there is provided a kind of antipruritic liquid medicine, it is to mainly by wet The pruitus of the initiations such as poison, food hypersenstivity, drug allergy has significant curative effect.
The technical solution used in the present invention is:A kind of antipruritic liquid medicine, it is made up of the following raw material component by quality proportioning: 400 ~ 550g of kuh-seng, 450 ~ 550g of Mozzie buster, enter 400 ~ 600g of earthworm, read 350 ~ 500g, 400 ~ 600g of ivy tree bark, spend in vain 450 ~ 550g of amphibious crab grass, 500 ~ 550g of Fruticose Breyniae Leaf and Twig's leaf, 300 ~ 700g of 450 ~ 550g of shinyleaf pricklyash root root and alcohol.
As the further improvement of such scheme, the antipruritic liquid medicine is made up of the following raw material component by quality proportioning:Kuh-seng 500g, Mozzie buster 500g, enter 400 ~ 600g of earthworm, read 350 ~ 500g, ivy tree bark 500g, spend amphibious crab grass 500g, black flour in vain Refreshing leaf 500g, shinyleaf pricklyash root root 500g and alcohol 500g.
In raw medicinal material selected by the present invention, its effect and pharmacological action are respectively:
Kuh-seng:Bitter, it is cold in nature.The thoughts of returning home, liver, stomach, large intestine, bladder warp.【Effect】For swelling of vulva pruritus vulvae, eczema, wet sore, skin scabies Itch.
Ivy tree bark:It is used as medicine with root skin, stem skin.Pungent hardship, it is cool in nature.【Effect】Antibacterial anti-inflammatory, relieving superficies by cooling, wind-dispelling are removed It is wet, stimulate the circulation of the blood and cause the muscles and joints to relax.
Spend amphibious crab grass in vain:Cool in nature, taste is flat.【Effect】Clearing liver lung heat, improving eyesight yin-nourishing, the scattered stasis of blood.
Fruticose Breyniae Leaf and Twig's leaf:Slight bitter, it is cool.It is slightly poisonous.【Effect】It is used for burn, eczema, allergic dermatitis, pruitus outside.
Shinyleaf pricklyash root root:Gas micro-perfume, pungent peppery numb tongue and it is bitter.【Effect】Dispelling wind and removing obstruction in the meridians, expel endogenous wind to relieve convulsion, subdhing swelling and detoxicating.
Mozzie buster:It is warm-natured and.【Effect】Disappear nameless gall.
Enter earthworm:With root, leaf and fruit medicine.【Effect】Traumatic injury, pruitus are controlled in external application.
Read on ground:Root and complete stool are used as medicine.【Effect】Removing toxicity for detumescence, dissolving stasis dampness removing.
Another technical scheme for being taken of the present invention is:A kind of preparation method of antipruritic liquid medicine as described above, it is pressed Quality proportioning weighs the various medicinal materials in raw material, is together placed in alcohol in glass container after being mixed uniformly through boiling or soaking System to liquid medicine quality is green, and filter and remove residue takes filtrate, produces antipruritic liquid medicine finished product.
It is described to boil the time for 1 day as the further improvement of such scheme;The soak time is 3 days.
As the further improvement of such scheme, it is described boil during control temperature in the range of 60 ~ 70 DEG C.
Rear be co-grinded into smalls, mistake are well mixed as the further improvement of such scheme, in addition to by various medicinal materials Load cloth bag after sieve, then be together placed in white wine in glass container.
The beneficial effects of the invention are as follows:The present invention has evaded original by the special selection to raw material components and ratio optimization Expect the mutual inhibition of compatibility, mutual restraint between two drugs, the choosing of the mutual-detoxication between medicinal material, make medicine mutual reinforcement between, mutually make effect significantly, its can quick flat azaleine spot, Relieving itching and eliminating swelling, its original work(is shown to its pruitus mainly triggered in vivo by wet poison, food hypersenstivity, drug allergy etc. Effect, and short treating period, curative effect are stable, have no toxic side effect.
Embodiment
The present invention is specifically described with reference to embodiment, in order to art personnel to the present invention Understand.It is necessary that herein the present invention will be further described it is emphasized that embodiment is only intended to, it is impossible to be interpreted as to this The limitation of invention protection domain, art person skilled in the art, the non-intrinsically safe made according to foregoing invention content to the present invention The modifications and adaptations of property, should still fall within protection scope of the present invention.Simultaneously following mentioned raw materials are unspecified, are Commercially available prod;The processing step or preparation method not referred in detail be processing step known to a person skilled in the art or Preparation method.
Embodiment 1
A kind of antipruritic liquid medicine, it is made up of the following raw material component by quality proportioning:Kuh-seng 400g, Mozzie buster 550g, enter earthworm 400 ~ 600g, read 350 ~ 500g, ivy tree bark 400g, spend in vain amphibious crab grass 500g, Fruticose Breyniae Leaf and Twig's leaf 520g, shinyleaf pricklyash root root 450g and Alcohol 700g.
Preparation method:
The various medicinal materials in above-mentioned raw materials are weighed by quality proportioning, uniform rear be co-grinded into smalls is mixed, is filled after sieving Enter cloth bag, it is green sealed soak to be together placed in glass container with alcohol 3 days to liquid medicine quality, and filter and remove residue takes filtrate, Produce antipruritic liquid medicine finished product.
Embodiment 2
A kind of antipruritic liquid medicine, it is made up of the following raw material component by quality proportioning:Kuh-seng 550g, Mozzie buster 540g, enter earthworm 400 ~ 600g, read 350 ~ 500g, ivy tree bark 600g, spend in vain amphibious crab grass 450g, Fruticose Breyniae Leaf and Twig's leaf 550g, shinyleaf pricklyash root root 550g and Alcohol 300.
Preparation method:
The various medicinal materials in above-mentioned raw materials are weighed by quality proportioning, uniform rear and alcohol is mixed and is together placed in glass container It is green through boiling 1 day to liquid medicine quality, filter and remove residue takes filtrate, produces antipruritic liquid medicine finished product.Controlled during wherein boiling Temperature is in the range of 60 ~ 70 DEG C.
Embodiment 3
A kind of antipruritic liquid medicine, it is made up of the following raw material component by quality proportioning:Kuh-seng 500g, Mozzie buster 500g, sparrow plum 500g, Ox blood son leaf 500g, ivy tree bark 500g, spend amphibious crab grass 500g, Fruticose Breyniae Leaf and Twig's leaf 500g, shinyleaf pricklyash root root 500g and alcohol in vain 500g。
Preparation method:
The various medicinal materials in above-mentioned raw materials are weighed by quality proportioning, uniform rear and alcohol is mixed and is together placed in glass container It is green through boiling 1 day to liquid medicine quality, filter and remove residue takes filtrate, produces antipruritic liquid medicine finished product.Controlled during wherein boiling Temperature is in the range of 60 ~ 70 DEG C.
Embodiment 4:Clinical practice
2008 to 2016 admitted patient 306 people altogether, average age 32 years old, using the course for the treatment of 2 ~ 15 days, according to following curative effect marks Standard, is treated for patient position of disease respectively using the preparation-obtained antipruritic liquid medicine of the embodiment of the present invention 3.
Criterion of therapeutical effect:
(1)Recovery from illness:Local pathology symptom eliminates, functional rehabilitation is normal, no discomfort.
(2)Effectively:Local pathology disease has alleviation or improved, and part is basic to recover, and also has uncomfortable or pathological symptom to exist.
(3)It is invalid:Local pathological symptom is present, no alleviation, keeps original state.
Treatment results are shown, wherein recovery from illness case 273;Effective case 33;Invalid case 0, i.e., total effective rate reaches To 100%, cure rate reaches 89.2%.
Above-described embodiment is the preferred embodiments of the present invention, all with similar technique of the invention and the equivalence changes made, The protection category of the present invention all should be belonged to.

Claims (6)

1. a kind of antipruritic liquid medicine, it is characterised in that be made up of the following raw material component by quality proportioning:400 ~ 550g of kuh-seng, mosquito repellent 450 ~ 550g of grass, enter 400 ~ 600g of earthworm, read 350 ~ 500g, 400 ~ 600g of ivy tree bark, spend 450 ~ 550g of amphibious crab grass in vain, it is black Face 500 ~ 550g of god's leaf, 300 ~ 700g of 450 ~ 550g of shinyleaf pricklyash root root and alcohol.
2. a kind of antipruritic liquid medicine according to claim 1, it is characterised in that quality proportioning group is pressed by the following raw material component Into:The young leaf 500g of kuh-seng 500g, Mozzie buster 500g, sparrow plum 500g, ox blood, ivy tree bark 500g, spend amphibious crab grass 500g, black flour in vain Refreshing leaf 500g, shinyleaf pricklyash root root 500g and alcohol 500g.
3. a kind of preparation method of antipruritic liquid medicine as claimed in claim 1 or 2, it is characterised in that:Original is weighed by quality proportioning Various medicinal materials in material, be mixed it is uniform after be together placed in alcohol in glass container through boiling or soak to liquid medicine quality is Green, filter and remove residue takes filtrate, produces antipruritic liquid medicine finished product.
4. a kind of preparation method of antipruritic liquid medicine according to claim 3, it is characterised in that:It is described to boil the time for 1 day; The soak time is 3 days.
5. a kind of preparation method of antipruritic liquid medicine according to claim 3, it is characterised in that:It is described boil during control Temperature is in the range of 60 ~ 70 DEG C.
6. a kind of preparation method of antipruritic liquid medicine according to claim 3, it is characterised in that:Also include mixing various medicinal materials Uniform rear be co-grinded into smalls is closed, cloth bag is loaded after sieving, then be together placed in glass container with white wine.
CN201710173696.1A 2017-03-22 2017-03-22 A kind of antipruritic liquid medicine Pending CN106963839A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710173696.1A CN106963839A (en) 2017-03-22 2017-03-22 A kind of antipruritic liquid medicine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710173696.1A CN106963839A (en) 2017-03-22 2017-03-22 A kind of antipruritic liquid medicine

Publications (1)

Publication Number Publication Date
CN106963839A true CN106963839A (en) 2017-07-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710173696.1A Pending CN106963839A (en) 2017-03-22 2017-03-22 A kind of antipruritic liquid medicine

Country Status (1)

Country Link
CN (1) CN106963839A (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
田燕等: "《中药临床新用途》", 30 June 2016, 金盾出版社 *

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Application publication date: 20170721

RJ01 Rejection of invention patent application after publication