CN103816349B - A kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus - Google Patents

Abstract

The invention discloses a kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus, relate to a kind of medicine treating infectious disease, it is characterized in that: it is made up of the raw material of Chinese medicine of following masses percentage ratio: Cornu Naemorhedi 8.2 10.1%, Cornu Bubali silk 13.8 16.9%, Gypsum Fibrosum 27.6 33.8%, Herba Commelinae 5.5 6.7%, Herba Violae 4.1 5.1%, Rhizoma Osmundae 2.8 3.4%, Hedyotidis Diffusae 4.1 5.1%, Herba Acalyphae 2.8 3.4%, Herba Verbenae 2.8 3.4%, Rhizoma Paridis 2.8 3.4%, Herba Sedi Emarginati 2.8 3.4%, Herba Euphorbiae Humifusae 2.8 3.4%, Rhizoma Fagopyri Dibotryis 2.8 3.4%, Herba Portulacae 4.1 5.1%, Herba Senecionis Scandentis 2.8 3.4%；This instant particles as Chinese medicine taking convenience, property is strong to the ill, and effective therapeutic effect is good soon, cure rate 98.53%, effective percentage 100%.

Description

A kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus

Technical field

The present invention relates to a kind of medicine treating infectious disease.Particularly relate to a kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus.

Background technology

Scrub typhus, also known as chigger poison, is equivalent to the scrub typhus described in western medicine.It is apt to occur in season in summer autumn rain quantity set.It is characterized as high heat, eschar, lymphadenectasis and erythra etc..This disease is the most on the books in the handbook of Prescription for Emergency of Ge Hong: " there is chigger between scenery with hills and waters more, the most carefully, the most invisible.People enters water-bath, and bathes with water bath, and this worm writes in the person, and cloudy day rain row grass in water, also writes people, just pierces flesh side.Its diagnostic method: the most red on first skin, such as Semen Phaseoli Semen Panici miliacei foxtail millet grain, with hands rub red on, pain such as thorn.After three days, make hundred joints strong, pain cold and heat, red upper skin ulcer.This worm is fade-in to bone, then kill a person." doctor trained in Western medicine thinks: scrub typhus is the acute infectious disease caused by rickettsia akamushi, is a kind of disease of natural focus, and muroid is major source of infection, and trombiculid is communication media.Clinical manifestation is: onset is the most unexpected, and body temperature rises rapidly, reaches more than 39～40 DEG C, companion shiver with cold, severe headache, extremities aching pain, Nausea and vomiting, constipation, Blushing, conjunctival congestion, cough, chest pain etc..Few patients tells pain and Rotation of eyeball pain after socket of the eye.Severe patient have the neurological symptom such as delirium, hard of hearing, mind change and heart rate speedup or slow down, the cardiovascular system symptoms such as microcirculation disturbance.Treatment uses the medicines such as chloromycetin, tetracycline, doxycycline, trimethoprim, uses adrenocortical hormone, heparin, diuretic, vasoactive agent to serious neurological system symptom, disseminated inravascular coagulation, heart failure, patients with septic shock or carries out fluid infusion etc..These medicines have certain curative effect, but side effect is big, especially women, child are disabled or are cautious use of, and relapse rate is high.The side effect of Chinese medicine is little, can cure primary disease；The traditional Chinese medical science is thought: when epidemic disease poison is bitten with louse and after invading blood vessels, heresy just disaccords, and head be simultaneous occurrence of syndromes of both QI and WEI systems, or evil poison is invaded and gallbladder is burnt with three, also can sick send out few the most positive, and followed by, epidemic disease poisons heat, gos deep into nutrient blood, burns bright the moon of fainting, priming chilly wind, or in close pericardium, upset gods.Epidemic disease poison outgoing skin, flees blood network and is macule, muscle of contaminating, and blocks meridians and causes head-body-pain.The Chinese patent medicine treating this disease at present is the fewest, and does not differentiates between pattern of syndrome treatment, affects the treatment.

Summary of the invention

It is an object of the invention to overcome the deficiencies in the prior art, it is provided that have a kind of property of suiting the medicine to the illness strong, effective soon, cure rate is high, and a kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus of taking convenience.

In order to reach object above, the technical solution used in the present invention is: this kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus, it is characterized in that: it is made up of the raw material of Chinese medicine of following masses percentage ratio: Cornu Naemorhedi 8.2-10.1%, Cornu Bubali silk 13.8-16.9%, Gypsum Fibrosum 27.6-33.8%, Herba Commelinae 5.5-6.7%, Herba Violae 4.1-5.1%, Rhizoma Osmundae 2.8-3.4%, Hedyotidis Diffusae 4.1-5.1%, Herba Acalyphae 2.8-3.4%, Herba Verbenae 2.8-3.4%, Rhizoma Paridis 2.8-3.4%, Herba Sedi Emarginati 2.8-3.4%, Herba Euphorbiae Humifusae 2.8-3.4%, Rhizoma Fagopyri Dibotryis 2.8-3.4%, Herba Portulacae 4.1-5.1%, Herba Senecionis Scandentis 2.8-3.4%；The most each raw material of Chinese medicine constituent content percent sum is equal to 100%.nullThis kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus is made by following steps: one、By Cornu Naemorhedi 8.2-10.1%、Cornu Bubali silk 13.8-16.9%、Gypsum Fibrosum 27.6-33.8%、Herba Commelinae 5.5-6.7%、Herba Violae 4.1-5.1%、Rhizoma Osmundae 2.8-3.4%、Hedyotidis Diffusae 4.1-5.1%、Herba Acalyphae 2.8-3.4%，Herba Verbenae 2.8-3.4%、Rhizoma Paridis 2.8-3.4%、Herba Sedi Emarginati 2.8-3.4%、Herba Euphorbiae Humifusae 2.8-3.4%、Rhizoma Fagopyri Dibotryis 2.8-3.4%、Herba Portulacae 4.1-5.1%、The ratio of Herba Senecionis Scandentis 2.8-3.4% accurately weighs and cooks each raw material of Chinese medicine，When weighing each raw material of Chinese medicine，The Cornu Naemorhedi that will weigh up、Cornu Bubali silk is mixed puts together，The Herba Violae that will weigh up、Hedyotidis Diffusae、Herba Acalyphae、Herba Senecionis Scandentis is mixed puts together，The Gypsum Fibrosum that will weigh up、Herba Commelinae、Rhizoma Osmundae、Herba Verbenae、Rhizoma Paridis、Herba Sedi Emarginati、Herba Euphorbiae Humifusae、Rhizoma Fagopyri Dibotryis、Herba Portulacae is mixed puts together；Two, the Herba Violae put together mixed, Hedyotidis Diffusae, Herba Acalyphae, Herba Senecionis Scandentis put into multi-function extractor, add domestic water, amount of water be Herba Violae, Hedyotidis Diffusae, Herba Acalyphae, 9-10 times of Herba Senecionis Scandentis quality sum, soak 20 minutes, heating extraction volatile oil, extraction time is 100 minutes, extract complete, take volatile oil cold preservation standby, by the medical filtration in tank body, stay slag, obtain filtering liquid medicine；nullThree、By the mixed Cornu Naemorhedi put together、Stainless-steel pan put into by Cornu Bubali silk，Add domestic water，Heating decocts，Amount of water is Cornu Naemorhedi、8-10 times of Cornu Bubali yarn quality sum，In decoction process，Add domestic water in time，Work as Cornu Naemorhedi、When Cornu Bubali silk decocting time reaches 150 minutes，By the mixed Gypsum Fibrosum put together、Herba Commelinae、Rhizoma Osmundae、Herba Verbenae、Rhizoma Paridis、Herba Sedi Emarginati、Herba Euphorbiae Humifusae、Rhizoma Fagopyri Dibotryis、Herba Portulacae puts into medicine boiler，Add domestic water，Soak 20 minutes，Amount of water is Gypsum Fibrosum、Herba Commelinae、Rhizoma Osmundae、Herba Verbenae、Rhizoma Paridis、Herba Sedi Emarginati、Herba Euphorbiae Humifusae、Rhizoma Fagopyri Dibotryis、7-8 times of Herba Portulacae quality sum，When intense fire is heated to boiling，The Cornu Naemorhedi that will decoct in stainless-steel pan、Cornu Bubali silk and decoction liquor are incorporated to medicine boiler，Change slow fire boiling 90 minutes，Stop heating，Filter，Stay slag，Obtain a medicinal liquid；Four, the medicinal residues in multi-function extractor are incorporated to medicine boiler, and in medicine boiler, add domestic water, amount of water is Cornu Naemorhedi, Cornu Bubali silk, Gypsum Fibrosum, Herba Commelinae, Herba Violae, Rhizoma Osmundae, Hedyotidis Diffusae, Herba Acalyphae, Herba Verbenae, Rhizoma Paridis, Herba Sedi Emarginati, Herba Euphorbiae Humifusae, Rhizoma Fagopyri Dibotryis, Herba Portulacae, 5-6 times of Herba Senecionis Scandentis quality sum, intense fire is heated to boiling, changes slow fire boiling 90 minutes, filters, waste, obtains secondary medicinal liquid；Five, filtering liquid medicine, medicinal liquid, a secondary medicinal liquid are incorporated into stainless steel cask, obtain admixing medical solutions；Six, adding chitin in admixing medical solutions, stir evenly, the addition of chitin is the 0.03% of admixing medical solutions quality, and 45 DEG C are incubated 10 hours, take supernatant liquid filtering, waste, obtain purification medicinal liquid；Seven, will purify medicinal liquid and add medicine boiler, heating concentrates, and is concentrated into relative density when being 1.30～1.35, stops heating, Temperature fall, obtain traditional Chinese medicine thick paste；Eight, in the traditional Chinese medicine thick paste be down to room temperature, dextrin is added; mix homogeneously; the addition of dextrin is the 6-8% of the raw material of Chinese medicine gross mass weighed up; being made the wet Chinese medicinal granule by a sieve by granulation machine, wet Chinese medicinal granule is put into the drip pan of baking oven, temperature control 45-50 DEG C is dried; when do to moisture less than 5% time; stop heating, Temperature fall, obtain thick Chinese medicinal granule；Nine, thick Chinese medicinal granule is rubbed with the hands broken, standby volatile oil is uniformly sprayed at and rubs with the hands on broken Chinese medicinal granule, put into airtight container and absorb volatile oil, after absorbing 48 hours, Bag for holding medicine, sealing, every bag of 7g, is a kind of instant particles as Chinese medicine finished product treating extreme noxious heat scrub typhus.

The prescription pharmacology of this kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus is: clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body, inducing diuresis to remove edema, and eliminating stasis to stop pain is antibacterial, antiviral.

Wherein: Cornu Naemorhedi salty in the mouth, cold in nature；GUIXIN, Liver Channel.There is heat clearing away, relieving convulsion, effect of eliminating stasis to stop pain.Pharmacological research: Cornu Naemorhedi has antivirus action.

Cornu Bubali silk bitter in the mouth, property are micro-salty, cold in nature；GUIXIN, liver, stomach warp.There is heat-clearing and toxic substances removing, effect of cooling blood for hemostasis.Cure mainly warm febrile disease to join the army blood, the high heat of intenseness of heat heated, coma, bleeding due to blood-heat send out speckle, epistaxis, infantile convulsion, larynx pharyngeal swelling, encephalitis b.

Gypsum Fibrosum acrid in the mouth, sweet, cold nature；Attach to the lung and stomach meridians.Having clearing away heat-fire, relieving restlessness is quenched the thirst, effect of convergence granulation promoting.Cure mainly dyspnea and cough due to lung-heat, restlessness and thirst, the high Sheng of stomach-fire, headache, toothache, gingival swelling and pain, eczema, do not hold back after skin infection is routed, burn due to hot liquid or fire.

Herba Commelinae sweet in the mouth, micro-hardship, cold in nature；Return lung, stomach, bladder warp.There is heat clearing away, removing toxic substances, diuresis, removing heat from blood, effect of removing toxic substances.Cure mainly edema, tinea pedis, dysuria, flu, erysipelas, parotitis, icterohepatitis, hematodiarrhoea, malaria, epistaxis, hematuria, metrorrhagia, leucorrhea, laryngopharynx swelling and pain, carbuncle furuncle.

Herba Violae bitter in the mouth, pungent, cold in nature；GUIXIN, spleen channel.There is effect of heat-clearing and toxic substances removing.Cure mainly epidemic febrile disease high heat irritated, influenza, infectious hepatitis, nephritis, scrofula, parotitis, furuncle and other pyogenic infection.Pharmacological research: water extract has inhibitory action to herpes simplex virus, can delay the cytopathogenic effect of Orphan virus；Making Herba Corydalis Bungeanae injection with herb, its effective ingredient is mainly alkaloid, has vitro antibacterial activity, to alpha streptococcus, streptococcus pneumoniae, micrococcus catarrhalis, dysentery bacterium, escherichia coli, bacillus pyocyaneus, staphylococcus, sarcina inhibitory action.

Rhizoma Osmundae bitter in the mouth, puckery, cold nature；Return liver, stomach warp.There is heat-clearing and toxic substances removing, hemostasis, effect of parasite killing.Cure mainly anemopyretic cold, encephalitis B, mumps, dysentery, discharging fresh blood stool, metrorrhagia, leukorrhagia, puerperal vim and vigour distending pain, ascarifuge and pinworm, pathopyretic ulcer.

Hedyotidis Diffusae bitter in the mouth, sweet, light, cold in nature；GUIXIN, liver, spleen channel.There is heat-clearing and toxic substances removing, effect of profit.Cure mainly dyspnea and cough due to lung-heat, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom, the puckery pain of pyretic stranguria, edema, dysentery, enteritis, jaundice due to damp-heat, be good at the multiple cancerous protuberance for the treatment of.

Herba Acalyphae bitter in the mouth, puckery, property is put down；GUIXIN, lung, large and small intestinal warp.There is heat-clearing and toxic substances removing, dampness removing, effect of astringing to arrest bleeding.Cure mainly enteritis, dysentery, spit blood, epistaxis, have blood in stool, hematuria, metrorrhagia, carbuncle furuncle infections, skin eczema.

Herba Verbenae bitter in the mouth, cool in nature；Return liver, spleen channel.There is heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation to remove blood stasis, effect of preventing the attack (or recurrence) of malaria.Cure mainly lump in the abdomen, amenorrhea dysmenorrhea, malaria, sore throat, carbuncle, edema, pyretic stranguria.

Rhizoma Paridis bitter in the mouth, cold nature；GUIXIN, Liver Channel.There is heat-clearing and toxic substances removing, antiasthmatic-antitussive, the effect of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., cure mainly and control carbuncle, furuncle, scrofula, sore throat, chronic tracheitis, infantile convulsion tic, snake bite and insect sting.

Herba Sedi Emarginati bitter in the mouth, acid, cool in nature；GUIXIN, Liver Channel.There is heat-clearing and toxic substances removing, hemostasis, effect of dampness removing.Cure mainly carbuncle furuncle, furuncle, herpes zoster, scrofula, spitting of blood, spit blood, epistaxis, have blood in stool, dysentery, gonorrhea, jaundice, metrorrhagia, leukorrhagia.

Herba Euphorbiae Humifusae acrid in the mouth, property is put down；Return lung, liver, stomach, large intestine, bladder warp.There is heat-clearing and toxic substances removing, dampness removing jaundice eliminating, effect of promoting blood circulation and hemostasis.Cure mainly dysentery, have loose bowels, jaundice, hemoptysis, spit blood, hematuria, have blood in stool, metrorrhagia, agalactia, treating swelling and pain by traumatic injury and pathopyretic ulcer etc..

Rhizoma Fagopyri Dibotryis acrid in the mouth, hardship, cool in nature；Return lung, spleen, stomach warp.There is heat-clearing and toxic substances removing, invigorating spleen to remove dampness, eliminating carbuncle of invigorating blood circulation, effect of expelling wind and removing dampness, cure mainly sore, snake bite and insect sting, lung abscess, lung-heat cough with asthma, laryngopharynx swelling and pain, dysentery, rheumatism arthromyodynia, traumatic injury.Pharmacological research: eliminate the phlegm, antipyretic, antiinflammatory, antitumor etc. act on.

Herba Portulacae sweet in the mouth, acid, cold in nature；GUIXIN, liver, spleen, large intestine channel.Having heat-clearing and toxic substances removing, diuretic dries, and dissipates blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, effect of hemostasis removing heat from blood.Curing mainly pyretic toxicity dysentery, enteritis, nephritis, puerperal, metrorrhagia, had blood in stool, mastitis, puerperal sweating due to debility, carbuncle sore tumefacting virus, snake bite and insect sting.

Herba Senecionis Scandentis bitter in the mouth, sweet, cold in nature；Return lung liver, liver, large intestine channel.There is heat-clearing and toxic substances removing, improving acuity of vision and removing nebula, effect of killing parasites for relieving itching.Curing mainly influenza, upper respiratory tract infection, pneumonia, acute tonsillitis, rib adenitis, acute enteritis, bacillary dysentery, icterohepatitis, gallbladder exudative dermatitis is scorching, acute urinary tract infection, conjunctival congestion and swelling pain cataracta, carbuncle furuncle poison, erysipelas, eczema, dry and wet tinea skin ulcer, trichomonal vaginitis, burn and scald.

The instructions of taking of this kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus is: warm boiled water half an hour after meal, 3 times on the one, and once a bag, adult doubles to take child.

Take medicine taboo: period of taking medicine avoids eating anything raw or cold, delicious food savoury food.

Having the beneficial effects that of this kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus: taking convenience, property is strong to the ill, and effective therapeutic effect is good soon, cure rate 98.53%, effective percentage 100%.

Analysis of clinical

One, diagnosis basis

" tcm diagnosis and Differential Diagnosis " scrub typhus diagnosis that the red legend cutting edge of a knife or a sword published according to People's Health Publisher is edited is formulated.

1, it is apt to occur in season in summer autumn rain quantity set, in sick first 3 weeks, went epidemic regions, and work out of doors, sleep in the open or TIANBIANCAO therefrom sitting and lying etc., or have muroid contact history.Onset is hurried.

2, being occurred kermesinus pimple at once by the place's of biting skin, to be centrally formed typical case's eschar, eschar is easily sent out in axillary fossa, groin, external genitalia, anus etc.；Core enlargement near eschar.

3, high fever does not moves back, irritated thirsty, general pain of having a headache, flushing conjunctival congestion, constipation.

4, red tongue, dry, rough and yellow fur, slippery and rapid pulse.

5, lab testing: total white blood cells is normal or reduces, and the course of disease often substantially reduces on the 2nd week, and neutrophilic granulocyte is on the low side, lymphocytosis；Outer Pei Shi experiments experiment is positive.

Two, efficacy evaluation

Formulate according to the efficacy assessment standard of People's Republic of China's traditional Chinese medicine industry standard one Chinese medical disease Standardization of diagnosis and curative effect (ZY-T001.1-94) scarlet fever.

1, cure: the speckle heat that disappears is moved back, and transference cure, hemogram is normal.

2, take a turn for the better: the speckle heat that disappears is moved back, and other symptoms are improved.

2, do not heal: the state of an illness fails to control or develop complications.

Three, efficacy result analysis

From in January, 2010 in December, 2012, making a definite diagnosis extreme noxious heat scrub typhus patient 68 example, wherein male patient 27 example, female patient 41 example altogether, sex ratio is 0.66:1.Oldest 86 years old, minimum 2 years old, less than 30 years old patient 8 example, account for the 11.76% of subject population；30-75 year patient 55 example, accounts for the 80.88% of subject population；More than 75 years old patient 5 examples, account for the 7.35% of subject population.Occupation, based on peasant (55 example), accounts for the 80.88% of subject population.Morbidity is grouped as 9-11 month, wherein example in October 55 month, accounts for the 80.88% of subject population.Take this kind of instant particles as Chinese medicine treating extreme noxious heat scrub typhus 7-10 days, cure 67 examples, cure rate 98.53%；Take a turn for the better 1 example, improvement rate 1.47%；Effective percentage 100%.

Specific embodiment

Embodiment 1

nullBy Cornu Naemorhedi 9.2%、Cornu Bubali silk 15.4%、Gypsum Fibrosum 30.7%、Herba Commelinae 6.1%、Herba Violae 4.6%、Rhizoma Osmundae 3.1%、Hedyotidis Diffusae 4.6%、Herba Acalyphae 3.1%、Herba Verbenae 3.1%、Rhizoma Paridis 3.1%、Herba Sedi Emarginati 3.1%、Herba Euphorbiae Humifusae 3.1%、Rhizoma Fagopyri Dibotryis 3.1%、Herba Portulacae 4.6%、The ratio of Herba Senecionis Scandentis 3.1% accurately weighs each raw material of Chinese medicine 30kg altogether，Wherein Cornu Naemorhedi 2.76kg、Cornu Bubali silk 4.62kg、Gypsum Fibrosum 9.21kg、Herba Commelinae 1.83kg、Herba Violae 1.38kg、Rhizoma Osmundae 0.93kg、Hedyotidis Diffusae 1.38kg、Herba Acalyphae 0.93kg、Herba Verbenae 0.93kg、Rhizoma Paridis 0.93kg、Herba Sedi Emarginati 0.93kg、Herba Euphorbiae Humifusae 0.93kg、Rhizoma Fagopyri Dibotryis 0.93kg、Herba Portulacae 1.38kg、Herba Senecionis Scandentis 0.93kg.When weighing each raw material of Chinese medicine, the Cornu Naemorhedi weighed up, Cornu Bubali silk are mixed and put together, the Herba Violae weighed up, Hedyotidis Diffusae, Herba Acalyphae, Herba Senecionis Scandentis are mixed and put together, the Gypsum Fibrosum weighed up, Herba Commelinae, Rhizoma Osmundae, Herba Verbenae, Rhizoma Paridis, Herba Sedi Emarginati, Herba Euphorbiae Humifusae, Rhizoma Fagopyri Dibotryis, Herba Portulacae are mixed and put together；The Herba Violae put together mixed, Hedyotidis Diffusae, Herba Acalyphae, Herba Senecionis Scandentis put into multi-function extractor, add domestic water 45kg, soak 20 minutes, heating extraction volatile oil, extraction time is 100 minutes, extracts complete, takes volatile oil cold preservation standby, by the medical filtration in tank body, stay slag, obtain filtering liquid medicine；By the mixed Cornu Naemorhedi put together, stainless-steel pan put into by Cornu Bubali silk, add domestic water 70kg, heating decocts, in decoction process, add domestic water in time, work as Cornu Naemorhedi, when Cornu Bubali silk decocting time reaches 150 minutes, by the mixed Gypsum Fibrosum put together, Herba Commelinae, Rhizoma Osmundae, Herba Verbenae, Rhizoma Paridis, Herba Sedi Emarginati, Herba Euphorbiae Humifusae, Rhizoma Fagopyri Dibotryis, Herba Portulacae puts into medicine boiler, add domestic water 140kg, soak 20 minutes, when intense fire is heated to boiling, the Cornu Naemorhedi that will decoct in stainless-steel pan, Cornu Bubali silk and decoction liquor are incorporated to medicine boiler, change slow fire boiling 90 minutes, stop heating, filter, stay slag, obtain a medicinal liquid；Medicinal residues in multi-function extractor being incorporated to medicine boiler, and adds domestic water 170kg in medicine boiler, intense fire is heated to boiling, changes slow fire boiling 90 minutes, filters, waste, obtains secondary medicinal liquid；Filtering liquid medicine, medicinal liquid, a secondary medicinal liquid are incorporated into stainless steel cask, obtain admixing medical solutions；Adding chitin in admixing medical solutions, stir evenly, the addition of chitin is the 0.03% of admixing medical solutions quality, and 45 DEG C are incubated 10 hours, take supernatant liquid filtering, waste, obtain purification medicinal liquid；To purify medicinal liquid and add medicine boiler, heating concentrates, and is concentrated into relative density when being 1.30～1.35, stops heating, Temperature fall, obtain traditional Chinese medicine thick paste；Dextrin 2.1kg is added in the traditional Chinese medicine thick paste be down to room temperature; mix homogeneously; the wet Chinese medicinal granule by a sieve is made by granulation machine; wet Chinese medicinal granule is put into the drip pan of baking oven; temperature control 45-50 DEG C be dried, when do to moisture less than 5% time, stop heating; Temperature fall, obtains thick Chinese medicinal granule 5.83kg；Thick Chinese medicinal granule is rubbed with the hands broken, standby volatile oil is uniformly sprayed at and rubs with the hands on broken Chinese medicinal granule, put into airtight container and absorb volatile oil, after absorbing 48 hours, Bag for holding medicine, sealing, every bag of 7g, be a kind of instant particles as Chinese medicine finished product treating extreme noxious heat scrub typhus.

Treat extreme noxious heat scrub typhus patient 21 example with this instant particles as Chinese medicine, cure 21 examples, cure rate 100%, effective percentage 100%.

Model case

Chu Lizhong, man, 66 years old, Xintai City Long Ting town great-grand father valley village peasant, to our hospital before 22 days October in 2010, main suit: heating occurred before 6 days, body temperature 38.5 DEG C, headache is obvious, to neighbouring clinic, infuse 3 days, less effective, body temperature rises to 39.6 DEG C, and face, trunk occur being dispersed in erythra, without pruritus, come to go to a doctor out of admiration for a famous person.Having a medical check-up: T39.5 DEG C, P90 beat/min, R23 beat/min, BP160/80mmHg, mucocutaneous without xanthochromia, face, trunk are shown in and are dispersed in congested maculopapule, see an eschar, do not touch enlarged lymph node at the groin of right side.Pharyngeal mucosa is without hyperemia, and tonsil is without enlargement, 90 times/min of heart rate, and auscultation of lung respiratory murmur is clear, and abdomen is put down soft, under liver, spleen rib not and, stool, urine is normal.Examine and see: patient facial region, trunk are shown in and are dispersed in congested maculopapule, see an eschar at the groin of right side, and rounded, coke black, edge slightly swells, and around has blush, without sufferings, without sepage.High fever does not moves back, irritated thirsty, general pain of having a headache, flushing conjunctival congestion.Red tongue, dry, rough and yellow fur, slippery and rapid pulse.Lab testing: leukocyte 3.8 × 10⁹/ L, neutrophilic granulocyte 40.54%, lymphocyte 47.99%；Outer Pei Shi experiments experiment is positive.Patient lives rural area, and there is scrub typhus case this locality.Being diagnosed as extreme noxious heat scrub typhus, take the treatment of this instant particles as Chinese medicine, after taking 3 days, body temperature is normal, and clinical symptom relief takes again 6 days, deflorescence, transference cure, and lab testing hemogram is normal.Advising and take 2 again, take a good rest, diet, still based on light, strengthened nutrition and is taken good care of one week.Follow up a case by regular visits to 1 year without recurrence.

Embodiment 2

nullBy Cornu Naemorhedi 8.5%、Cornu Bubali silk 16.5%、Gypsum Fibrosum 30.5%、Herba Commelinae 6.5%、Herba Violae 4.5%、Rhizoma Osmundae 2.8%、Hedyotidis Diffusae 5.0%、Herba Acalyphae 2.8%、Herba Verbenae 3.2%、Rhizoma Paridis 3.2%、Herba Sedi Emarginati 2.8%、Herba Euphorbiae Humifusae 3.2%、Rhizoma Fagopyri Dibotryis 2.8%、Herba Portulacae 4.5%、The ratio of Herba Senecionis Scandentis 3.2% accurately weighs each raw material of Chinese medicine 30kg altogether，Wherein Cornu Naemorhedi 2.55kg、Cornu Bubali silk 4.95kg、Gypsum Fibrosum 9.15kg、Herba Commelinae 1.95kg、Herba Violae 1.35kg、Rhizoma Osmundae 0.84kg、Hedyotidis Diffusae 1.5kg、Herba Acalyphae 0.84kg、Herba Verbenae 0.96kg、Rhizoma Paridis 0.96kg、Herba Sedi Emarginati 0.84kg、Herba Euphorbiae Humifusae 0.96kg、Rhizoma Fagopyri Dibotryis 0.84kg、Herba Portulacae 1.35kg、Herba Senecionis Scandentis 0.96kg.

Manufacture method is with embodiment 1

Treating extreme noxious heat scrub typhus patient 27 example with this instant particles as Chinese medicine, cure 26 examples, cure rate 96.3%, take a turn for the better 1 example, improvement rate 3.7%, effective percentage 100%.

Model case

Shao Xia, female, 40 years old, Laiwu steel enterprise workman.Within 2011, JIUYUE is to our hospital before 21 days, main suit: without obvious inducement, heating occurred before 5 days, body temperature 38-39 DEG C, without fear of cold, headache is substantially, general pain is weak, appetite is poor, is in by oral " three nine-day periods after the winter solstice cold drug, cefaclor, the acetaminophen " less effective of flu, and body temperature rises to 39.3 DEG C, and in yesterday trunk, face erythra occurs, without pruritus.Examining and see: patient temperature 39.0 DEG C, face, cervical region, trunk are shown in and are dispersed in maculopapule, see an eschar at pudendum, circular, diameter about 10mm, coke black, without pruritus, touch enlarged lymph node at the groin of right side, touch a tender spot obvious.Red tongue, dry, rough and yellow fur, slippery and rapid pulse.Lab testing: leukocyte 3.9 × 10⁹/ L, neutrophilic granulocyte 41.74%, lymphocyte 45.94%；Outer Pei Shi experiments experiment is positive.Meadow, field is had to play history before first quarter moon.Being diagnosed as extreme noxious heat scrub typhus, take the treatment of this instant particles as Chinese medicine, after taking 3 days, body temperature is normal, takes again 7 deflorescences, and without uncomfortable, lab testing hemogram is normal.Advise and take again 2, take a good rest, diet still based on light,

Strengthen nutrition and take good care of one week.Follow up a case by regular visits to 1 year without recurrence.

Embodiment 3

nullBy Cornu Naemorhedi 10.0%、Cornu Bubali silk 14.5%、Gypsum Fibrosum 31.0%、Herba Commelinae 6.0%、Herba Violae 5.0%、Rhizoma Osmundae 3.2%、Hedyotidis Diffusae 4.5%、Herba Acalyphae 3.2%、Herba Verbenae 2.8%、Rhizoma Paridis 2.8%、Herba Sedi Emarginati 3.2%、Herba Euphorbiae Humifusae 2.8%、Rhizoma Fagopyri Dibotryis 3.2%、Herba Portulacae 5.0%、The ratio of Herba Senecionis Scandentis 2.8% accurately weighs each raw material of Chinese medicine 30kg altogether，Wherein Cornu Naemorhedi 3kg、Cornu Bubali silk 4.35kg、Gypsum Fibrosum 9.3kg、Herba Commelinae 1.8kg、Herba Violae 1.5kg、Rhizoma Osmundae 0.96kg、Hedyotidis Diffusae 1.35kg、Herba Acalyphae 0.96kg、Herba Verbenae 0.84kg、Rhizoma Paridis 0.84kg、Herba Sedi Emarginati 0.96kg、Herba Euphorbiae Humifusae 0.84kg、Rhizoma Fagopyri Dibotryis 0.96kg、Herba Portulacae 1.5kg、Herba Senecionis Scandentis 0.84kg.

Manufacture method is with embodiment 1.

Treat extreme noxious heat scrub typhus patient 20 example with this instant particles as Chinese medicine, cure 20 examples, cure rate 100%, effective percentage 100%.

Model case

Liu Zhenfang, man, 57 years old, Gangcheng District, Laiwu Hu Jiazhai village of Mt. Ai subdistrict office peasant, on November 3rd, 2012 comes to go to a doctor.Main suit: before 3 days occur heating, body temperature 38.0 DEG C, have a headache general pain, press common cold treatment, less effective at this village health posts, body temperature rises to 39.0 DEG C, and in yesterday trunk, face erythra occurs, then go to a doctor.Examining and see: patient temperature 38.9 DEG C, face, trunk are shown in and are dispersed in maculopapule, see an eschar at axillary fossa, oval, diameter about 8mm, coke black, without pruritus, touch axillary lymph and tie enlargement.Red tongue, dry, rough and yellow fur, slippery and rapid pulse.Lab testing: leukocyte 5.2 × 10⁹/ L, neutrophilic granulocyte 59.10%, lymphocyte 40.01%；Outer Pei Shi experiments experiment is positive.Patient's these administrative affairs of village agriculture, has a vegetable plot near residence, time see there is muroid activity.Being diagnosed as extreme noxious heat scrub typhus, take the treatment of this instant particles as Chinese medicine, after taking 3 days, body temperature is normal, and erythra starts to disappear, and takes again 7 days transference cures, and lab testing hemogram is normal.Advising and take 2 again, take a good rest, diet, based on light, strengthened nutrition and is taken good care of one week.Follow up a case by regular visits to 1 year without recurrence.

Claims (1)

1. the instant particles as Chinese medicine treating extreme noxious heat scrub typhus, it is characterised in that: it is by following masses hundred The raw material of Chinese medicine of proportion by subtraction is made: Cornu Naemorhedi 8.2-10.1%, Cornu Bubali silk 13.8-16.9%, Gypsum Fibrosum 27.6-33.8%, Herba Commelinae 5.5-6.7%, Herba Violae 4.1-5.1%, Rhizoma Osmundae 2.8-3.4%, Hedyotidis Diffusae 4.1-5.1%, Herba Acalyphae 2.8-3.4%, Herba Verbenae 2.8-3.4%, Rhizoma Paridis 2.8-3.4%, Herba Sedi Emarginati 2.8-3.4%, Herba Euphorbiae Humifusae 2.8-3.4%, Rhizoma Fagopyri Dibotryis 2.8-3.4%, Herba Portulacae 4.1-5.1%, Herba Senecionis Scandentis 2.8-3.4%；The most each Chinese medicine is former Material constituent content percent sum is equal to 100%；This is a kind of treat the instant particles as Chinese medicine of extreme noxious heat scrub typhus by Following steps make: one, by Cornu Naemorhedi 8.2-10.1%, Cornu Bubali silk 13.8-16.9%, Gypsum Fibrosum 27.6-33.8%, Herba Commelinae 5.5-6.7%, Herba Violae 4.1-5.1%, Rhizoma Osmundae 2.8-3.4%, Hedyotidis Diffusae 4.1-5.1%, Herba Acalyphae 2.8-3.4%, Herba Verbenae 2.8-3.4%, Rhizoma Paridis 2.8-3.4%, Herba Sedi Emarginati 2.8-3.4%, Herba Euphorbiae Humifusae 2.8-3.4%, Rhizoma Fagopyri Dibotryis 2.8-3.4%, Herba Portulacae 4.1-5.1%, the ratio of Herba Senecionis Scandentis 2.8-3.4% accurately weigh cook each in Medicine raw material, when weighing each raw material of Chinese medicine, mixes put together the Cornu Naemorhedi weighed up, Cornu Bubali silk, will claim Good Herba Violae, Hedyotidis Diffusae, Herba Acalyphae, Herba Senecionis Scandentis is mixed puts together, by the Gypsum Fibrosum weighed up, Herba Commelinae, Rhizoma Osmundae, Herba Verbenae, Rhizoma Paridis, Herba Sedi Emarginati, Herba Euphorbiae Humifusae, Rhizoma Fagopyri Dibotryis, Herba Portulacae mix and put together；Two, The Herba Violae put together mixed, Hedyotidis Diffusae, Herba Acalyphae, Herba Senecionis Scandentis put into multi-function extractor, adding life and using Water, amount of water be Herba Violae, Hedyotidis Diffusae, Herba Acalyphae, 9-10 times of Herba Senecionis Scandentis quality sum, soak 20 points Clock, heating extraction volatile oil, extraction time is 100 minutes, extracts complete, takes volatile oil cold preservation standby, By the medical filtration in tank body, stay slag, obtain filtering liquid medicine；Three, Cornu Naemorhedi, the Babalus bubalis L. put together will be mixed Stainless-steel pan put into by angle silk, adds domestic water, and heating decocts, and amount of water is Cornu Naemorhedi, Cornu Bubali yarn quality 8-10 times of sum, in decoction process, adds domestic water in time, when Cornu Naemorhedi, Cornu Bubali silk decoct When time reaches 150 minutes, the Gypsum Fibrosum put together mixed, Herba Commelinae, Rhizoma Osmundae, Herba Verbenae, Rhizoma Paridis, Herba Sedi Emarginati, Herba Euphorbiae Humifusae, Rhizoma Fagopyri Dibotryis, Herba Portulacae put into medicine boiler, add domestic water, soak 20 minutes, Amount of water be Gypsum Fibrosum, Herba Commelinae, Rhizoma Osmundae, Herba Verbenae, Rhizoma Paridis, Herba Sedi Emarginati, Herba Euphorbiae Humifusae, Rhizoma Fagopyri Dibotryis, 7-8 times of Herba Portulacae quality sum, intense fire be heated to boiling time, by the Cornu Naemorhedi decocted in stainless-steel pan, Cornu Bubali silk and decoction liquor are incorporated to medicine boiler, change slow fire boiling 90 minutes, stop heating, filter, stay slag, Obtain a medicinal liquid；Four, the medicinal residues in multi-function extractor are incorporated to medicine boiler, and in medicine boiler, add life With water, amount of water be Cornu Naemorhedi, Cornu Bubali silk, Gypsum Fibrosum, Herba Commelinae, Herba Violae, Rhizoma Osmundae, Hedyotidis Diffusae, Herba Acalyphae, Herba Verbenae, Rhizoma Paridis, Herba Sedi Emarginati, Herba Euphorbiae Humifusae, Rhizoma Fagopyri Dibotryis, Herba Portulacae, Herba Senecionis Scandentis quality sum 5-6 times, intense fire be heated to boiling, change slow fire boiling 90 minutes, filter, waste, obtain secondary medicinal liquid；Five, Filtering liquid medicine, medicinal liquid, a secondary medicinal liquid are incorporated into stainless steel cask, obtain admixing medical solutions；Six, to mixing Adding chitin in medicinal liquid, stir evenly, the addition of chitin is the 0.03% of admixing medical solutions quality, 45 DEG C of insulations 10 hours, take supernatant liquid filtering, waste, obtain purification medicinal liquid；Seven, medicinal liquid will be purified and add medicine boiler, add Heat concentrates, and is concentrated into relative density when being 1.30～1.35, stops heating, Temperature fall, obtain traditional Chinese medicine thick paste； Eight, adding dextrin in the traditional Chinese medicine thick paste be down to room temperature, mix homogeneously, the addition of dextrin is to weigh up The 6-8% of medicine raw material gross mass, is made the wet Chinese medicinal granule by a sieve by granulation machine, by wet Chinese medicinal granule Put into the drip pan of baking oven, temperature control 45-50 DEG C be dried, when do to moisture less than 5% time, stop heating, Temperature fall, obtains thick Chinese medicinal granule；Nine, thick Chinese medicinal granule is rubbed with the hands broken, standby volatile oil is uniformly sprayed Rubbing with the hands on broken Chinese medicinal granule, putting into airtight container and absorb volatile oil, after absorbing 48 hours, Bag for holding medicine, Sealing, every bag of 7g, it is a kind of instant particles as Chinese medicine finished product treating extreme noxious heat scrub typhus.