CN106928312A - 一种雷公藤内酯醇衍生物、其制备方法和用途 - Google Patents
一种雷公藤内酯醇衍生物、其制备方法和用途 Download PDFInfo
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- CN106928312A CN106928312A CN201710192654.2A CN201710192654A CN106928312A CN 106928312 A CN106928312 A CN 106928312A CN 201710192654 A CN201710192654 A CN 201710192654A CN 106928312 A CN106928312 A CN 106928312A
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- compound
- triptolide
- alcohol derivative
- sulfydryl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
- C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
- C07J73/003—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (9)
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Cited By (4)
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CN107892709A (zh) * | 2017-11-27 | 2018-04-10 | 延边大学 | 对硝基苯氧基白桦脂醇基(28)甲酰酯及以其合成的白桦酯醇衍生物、制备方法及应用 |
CN112011543A (zh) * | 2019-05-30 | 2020-12-01 | 湖南大学 | 一种雷公藤甲素核酸适配体偶联物的制备方法 |
JP2021504455A (ja) * | 2018-04-02 | 2021-02-15 | シンカテ ファーマシューティカル インターミディエーツ カンパニー リミテッド | トリプトリド誘導体およびその製造方法と使用 |
WO2021134272A1 (zh) * | 2019-12-30 | 2021-07-08 | 广东省中医院 | 丙烯酸雷公藤甲素酯、其制备方法及其应用 |
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CN101288671B (zh) * | 2008-04-17 | 2010-12-01 | 首都医科大学 | 雷公藤单体化合物在提高腺相关病毒载体介导的基因表达效率及其对神经退行性疾病的辅助治疗中的用途 |
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Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107892709A (zh) * | 2017-11-27 | 2018-04-10 | 延边大学 | 对硝基苯氧基白桦脂醇基(28)甲酰酯及以其合成的白桦酯醇衍生物、制备方法及应用 |
CN107892709B (zh) * | 2017-11-27 | 2020-04-03 | 延边大学 | 一种白桦酯醇衍生物、制备方法及应用 |
JP2021504455A (ja) * | 2018-04-02 | 2021-02-15 | シンカテ ファーマシューティカル インターミディエーツ カンパニー リミテッド | トリプトリド誘導体およびその製造方法と使用 |
JP7096559B2 (ja) | 2018-04-02 | 2022-07-06 | シンカテ ファーマシューティカル インターミディエーツ カンパニー リミテッド | トリプトリド誘導体およびその製造方法と使用 |
CN112011543A (zh) * | 2019-05-30 | 2020-12-01 | 湖南大学 | 一种雷公藤甲素核酸适配体偶联物的制备方法 |
WO2021134272A1 (zh) * | 2019-12-30 | 2021-07-08 | 广东省中医院 | 丙烯酸雷公藤甲素酯、其制备方法及其应用 |
JP2023503530A (ja) * | 2019-12-30 | 2023-01-30 | グゥアンドン プロビンシャル ホスピタル オブ ティーシーエム | アクリル酸トリプトリド、その調製方法および用途 |
US11660285B2 (en) | 2019-12-30 | 2023-05-30 | Guangdong Provincial Hospital of TCM | Triptolide acrylate, preparation method therefor and use thereof |
JP7353500B2 (ja) | 2019-12-30 | 2023-09-29 | グゥアンドン プロビンシャル ホスピタル オブ ティーシーエム | アクリル酸トリプトリド、その調製方法および用途 |
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