CN106924531A - Treat Chinese medicine composition of porcine mycoplasmal pneumonia and preparation method thereof - Google Patents

Treat Chinese medicine composition of porcine mycoplasmal pneumonia and preparation method thereof Download PDF

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Publication number
CN106924531A
CN106924531A CN201511022551.9A CN201511022551A CN106924531A CN 106924531 A CN106924531 A CN 106924531A CN 201511022551 A CN201511022551 A CN 201511022551A CN 106924531 A CN106924531 A CN 106924531A
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CN
China
Prior art keywords
chinese medicine
medicine composition
parts
porcine mycoplasmal
mycoplasmal pneumonia
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Pending
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CN201511022551.9A
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Chinese (zh)
Inventor
陈庆忠
安同伟
李迎梅
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TIANJIN ZHONGGAO BIOTECHNOLOGY CO Ltd
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TIANJIN ZHONGGAO BIOTECHNOLOGY CO Ltd
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Priority to CN201511022551.9A priority Critical patent/CN106924531A/en
Publication of CN106924531A publication Critical patent/CN106924531A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/69Polygalaceae (Milkwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969Polygonatum (Solomon's seal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The present invention relates to a kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia, the component and its ratio of weight and number of its Chinese medicine composition are:Coptis 10-40 parts;Root of large-flowered skullcap 10-35 parts;Balloonflower root 5-25 parts;Radix Glycyrrhizae 10-40 parts;Radix scrophulariae 20-45 parts;Asian puccoon 5-30 parts;Feltwort 10-30 parts;Radix polygonati officinalis 10-50 parts;Polygala 5-30 parts.Inventive formulation composition is scientific and reasonable, and easy to use, cost is relatively low, to the treatment rate of porcine mycoplasmal pneumonia 90% or so.

Description

Treat Chinese medicine composition of porcine mycoplasmal pneumonia and preparation method thereof
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia and its Preparation method.
Background technology
Porcine mycoplasmal pneumonia is a kind of chronic respiratory infectious disease for causing pig by mycoplasma hyopneumoniae.At present, According to China's drug in some provinces Large-scale pig farm serologic test, porcine mycoplasmal pneumonia positive rate 30%~50%. This disease is distributed widely in all over the world, has generation on the pig farm in many areas of China.Due to the sick pig that carries disease germs Presence and distribution face it is wider, except directly occur death in addition to, sick pig grows slowly, growth rate reduce 15% or so, efficiency of feed utilization reduction by 20% causes the waste of feed and manpower.Have as cad pig or Scabies secondary infection is dead.Caused economic loss is very big, is to endanger one of important epidemic disease that pig industry develops.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia, the Chinese medicine group Compound have moisten the lung and relieve the cough, clearing heat and detoxicating effect, drug residue free is easy to use, can effectively treat The symptom such as cough and asthma in porcine mycoplasmal pneumonia.
It is another object of the present invention to provide a kind of system of the Chinese medicine composition for treating porcine mycoplasmal pneumonia Preparation Method.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia, the component and its weight portion of its Chinese medicine composition Counting ratio is:
And, the Chinese medicine composition component and its optimal ratio of weight and number are respectively:
A kind of preparation method of the Chinese medicine composition for treating porcine mycoplasmal pneumonia, its step is as follows:
(1) coptis, the root of large-flowered skullcap, balloonflower root, Radix Glycyrrhizae, radix scrophulariae, Asian puccoon, hair are weighed respectively according to weight proportion Stamen flower, radix polygonati officinalis, polygala add 5~15 times of water to be decocted three times, every time 10~40 points after soaking 15~50 minutes Clock, collecting decoction, is filtrated to get filtrate, standby;
(2) step (1) gained filtrate is concentrated into relative density 1.0~1.2, obtains final product treatment porcine mycoplasmal The Chinese medicine composition finished product of pneumonia.
Advantages of the present invention and beneficial effect are:
1st, in the Chinese medicine composition of this treatment porcine mycoplasmal pneumonia it is the coptis, the root of large-flowered skullcap, balloonflower root, Radix Glycyrrhizae, profound Ginseng, Asian puccoon, feltwort, radix polygonati officinalis and polygala as natural traditional Chinese medicine composition, with moistening the lung and relieve the cough well, Clearing heat and detoxicating effect, drug residue free is easy to use, effectively can treat porcine mycoplasmal pneumonia and cause The symptom such as lung heat, cough.
2nd, in the Chinese medicine composition of this treatment porcine mycoplasmal pneumonia balloonflower root, radix polygonati officinalis and radix scrophulariae eliminating phlegm and relieving cough, It is respectively provided with effect of anti-inflammatory, antibacterial while purging intense heat and detonicating, Asian puccoon then its promoting blood circulation work(after clearing heat and detoxicating Also can more protrude, have no toxic side effect, medicament residue will not be produced, can effectively treat porcine mycoplasmal pneumonia The diseases such as the blood strangury blood-head for triggering afterwards.
Specific embodiment
The present invention is described in further detail by following examples.It should be noted that:Following embodiments are explanations Property, it is not limited, it is impossible to limit protection scope of the present invention with following embodiments.
The coptis, the root of large-flowered skullcap in instant component, balloonflower root, Radix Glycyrrhizae, radix scrophulariae, Asian puccoon, feltwort, radix polygonati officinalis Can be commercially commercially available with polygala.
Embodiment 1
A kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia, the component and its weight point of its Chinese medicine composition It is not:Coptis 10g, root of large-flowered skullcap 10g, balloonflower root 5g, Radix Glycyrrhizae 10g, radix scrophulariae 20g, Asian puccoon 5g, feltwort 10g, radix polygonati officinalis 20g and polygala 5g.
A kind of preparation method of the Chinese medicine composition for treating porcine mycoplasmal pneumonia, its step is as follows:
(1) coptis, the root of large-flowered skullcap, balloonflower root, Radix Glycyrrhizae, radix scrophulariae, Asian puccoon, hair are weighed respectively according to weight proportion Stamen flower, radix polygonati officinalis, polygala add 5~15 times of water to be decocted three times, every time 10~40 points after soaking 15~50 minutes Clock, collecting decoction, is filtrated to get filtrate, standby;
(2) step (1) gained filtrate is concentrated into relative density 1.0~1.2, obtains final product treatment porcine mycoplasmal The Chinese medicine composition finished product of pneumonia.
Embodiment 2
A kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia, the component and its weight point of its Chinese medicine composition It is not:Coptis 25g, root of large-flowered skullcap 25g, balloonflower root 20g, Radix Glycyrrhizae 30g, radix scrophulariae 30g, Asian puccoon 25g, Mao Rui Flower 20g, radix polygonati officinalis 30g and polygala 20g.
The step of its preparation method, is with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia, the component and its weight point of its Chinese medicine composition It is not:Coptis 40g, root of large-flowered skullcap 35g, balloonflower root 25g, Radix Glycyrrhizae 40g, radix scrophulariae 45g, Asian puccoon 30g, Mao Rui Flower 30g, radix polygonati officinalis 50g and polygala 30g.
The step of its preparation method, is with embodiment 1.
The present invention treat porcine mycoplasmal pneumonia during, using the present invention with drinking water according to 1:50 Proportions drink, by the batheroom scale 1.5ml/kg of pig, once a day, continuously uses 5 days as one therapeutic course.
Clinical practice is tested
The upper 1-6 months in 2013, my company is successively 215, the domestic pig farm in Tianjin Ninghe two affected pig mycoplasma The sick pig of pneumonia provides free drug therapy, and Follow-up observation have recorded medication effect.It is final to cure sick pig 200, up to more than 90%, the therapeutic process in conjunction with two domestic pig farms does the average cure rate of Liang Ge plants To describe in detail:
1st, 1 is tested
Cultivation 1 75 is made a definite diagnosis or doubtful Eaton agent pneumonia affected pig, and main performance is as follows:Hyperpyrexia, cough Pant, expiratory dyspnea anorexia occurs and even gives up absolutely, is slow in action, slightly random by hair.By the present invention Medicament application method is administered, once a day, for three days on end after, it is seen that most of affected pig breathes asthma symptom Take a turn for the better, feed intake is obviously improved, gloss is gradually showed by hair, temperature recovery is normal, and activity coordination is able to Improve, cure sick pig 72 altogether later within 5 days, death, cure rate 96% do not occur.
2nd, 2 are tested
2 140 sick pigs of cultivation, main performance is as follows:Hyperpyrexia, anorexia, in abdominal respiration, It is most of to be slow in action, occur rear arch during cough and rise, neck is stretched, the manifest symptom such as sagging, through making a definite diagnosis It is porcine mycoplasmal pneumonia.It is administered by medicament application method of the present invention, once a day, after continuous 2 days, just It can be seen that most of affected pig honey stomach, sound of stridulating disappears, and cough symptom mitigates, and temperature recovery is normal, OK It is dynamic to become more flexibly, cure sick pig 135 altogether later within 5 days, there is not death, cure rate 96.43%.

Claims (3)

1. a kind of Chinese medicine composition for treating porcine mycoplasmal pneumonia, it is characterised in that:The Chinese medicine The component and its ratio of weight and number of composition be:
2. it is according to claim 1 treatment porcine mycoplasmal pneumonia Chinese medicine composition, its It is characterised by:The Chinese medicine composition component and its optimal ratio of weight and number are respectively:
3. a kind of Chinese medicine composition for the treatment of porcine mycoplasmal pneumonia as claimed in claim 1 Preparation method, it is characterised in that:The step of preparation method is:
(1) coptis, the root of large-flowered skullcap, balloonflower root, Radix Glycyrrhizae, radix scrophulariae, purple are weighed respectively according to weight proportion Grass, feltwort, radix polygonati officinalis, polygala add 5~15 times of water to be decocted three times after soaking 15~50 minutes, 10~40 minutes every time, collecting decoction, filtrate is filtrated to get, it is standby;
(2) step (1) gained filtrate is concentrated into relative density 1.0~1.2, obtains final product treatment pig The Chinese medicine composition finished product of Eaton agent pneumonia.
CN201511022551.9A 2015-12-29 2015-12-29 Treat Chinese medicine composition of porcine mycoplasmal pneumonia and preparation method thereof Pending CN106924531A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201511022551.9A CN106924531A (en) 2015-12-29 2015-12-29 Treat Chinese medicine composition of porcine mycoplasmal pneumonia and preparation method thereof

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Application Number Priority Date Filing Date Title
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768239A (en) * 2012-10-24 2014-05-07 天津中敖生物科技有限公司 Traditional Chinese medicine composition for preventing and treating swine mycoplasmal pneumonia and preparation method of traditional Chinese medicine composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768239A (en) * 2012-10-24 2014-05-07 天津中敖生物科技有限公司 Traditional Chinese medicine composition for preventing and treating swine mycoplasmal pneumonia and preparation method of traditional Chinese medicine composition

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