CN103893591A - Traditional Chinese medicine for treating chronic obstructive pulmonary disease - Google Patents

Traditional Chinese medicine for treating chronic obstructive pulmonary disease Download PDF

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CN103893591A
CN103893591A CN201410120958.4A CN201410120958A CN103893591A CN 103893591 A CN103893591 A CN 103893591A CN 201410120958 A CN201410120958 A CN 201410120958A CN 103893591 A CN103893591 A CN 103893591A
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herba
chinese medicine
obstructive pulmonary
chronic obstructive
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毛杰
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Abstract

The invention relates to a traditional Chinese medicine for treating chronic obstructive pulmonary disease. The traditional Chinese medicine is prepared from the following medicines by weight: 5 parts of clerodendrum fortunatum, 25 parts of wing nut fruit, 15 parts of radix ranunculi ternate, 5 parts of common adenostema herb, 15 parts of phaenosperma globosa, 10 parts of gelsemium elegan, 9 parts of hyssopus officinalis, 15 parts of bodinier beautyberry root, 30 parts of six-eared blumea, 15 parts of calamint, 5 parts of inula racemosa and 15 parts of microtoena insuavis. Clinical experiments prove that the traditional Chinese medicine can treat chronic obstructive pulmonary disease safely and effectively.

Description

A kind of Chinese medicine for the treatment of chronic obstructive pulmonary disease
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of chronic obstructive pulmonary disease.
Background technology
Chronic obstructive pulmonary disease (Chronic Obstructive Pulmonary Disease, COPD) is a kind of important chronic respiratory system diseases, and number of patients is many, and case fatality rate is high.Because it slowly carries out sexual development, have a strong impact on patient's work capacity and quality of life.COPD patient is after acute attack stage, though clinical symptoms is alleviated to some extent, its pulmonary function is still continuing deterioration, and due to the reduction of self-defense and immunologic function and the impact of extraneous various harmful factors, often outbreak repeatedly, and produce gradually various Cardiopulmonary Complications.COPD comprises two classes: chronic bronchitis and emphysema.The cause of disease is mainly owing to smoking.Clinical main manifestations is cough, dyspnea, pant and uncomfortable in chest etc.
Still lack at present the effective medicine of generally recognized as safe for chronic obstructive pulmonary disease.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Herba Clerodendri fortunati [source] is remitted paulownia platymiscium Herba Clerodendri fortunati Clerodendron fortunatum L. for Herba Verbenae, is used as medicine with root or Herb.Can adopt the whole year, cleans, and section is dried.[function cures mainly] heat-clearing and toxic substances removing, cough-relieving analgesic therapy.For cold, fever, pharyngolaryngitis, bronchitis, pulmonary tuberculosis hectic fever, stomachache, colic; Traumatic injury, furuncle furuncle and phyma.
Fructus pterocaryae stnopterae [source] is juglandaceae plant Pterocarya Stenoptera Pterocarya stenoptera C.D C.[P.ste-roptera C.DC.var.sinensis Graebn] fruit.Summer, season, fruit closely gathered when ripe, using fresh herb or dry.[function cures mainly] warming the lung to relieve cough; Removing toxic substances sore.Main cough due to wind and cold; Sore swollen toxin; Epidemic blisters.
Radix Ranunculi Ternati [source] be hair the plant Herba Ranunculi Japonici Ranunculus ternatus Thunb.[R.zuccarinii Miq. of section] tuber or herb.After plantation 2-3, excavate in Qiu Mo or early spring.After digging back, remove stem and leaf and fibrous root, clean earth, dry.[function cures mainly] removing toxic substances; Dissipating phlegm and resolving masses.Cure mainly scrofula; Tuberculosis; Pharyngitis; Furuncle; Venom; Malaria; Migraine; Toothache.
Adenostemma laveniaKuntze [source] belongs to adenostemma laveniaKuntze Adenostemma lavenia (L.) Kuntze for Compositae adenostemma laveniaKuntze, with all herbal medicine.Summer, autumn gather, and wash to earn and dry.[function cures mainly] clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling.Be used for catching a cold high hot, bronchitis, pharyngolaryngitis, tonsillitis, icterohepatitis; Carbuncle furuncle infections, venom are controlled in external.
Herba Phaenospermatis globosae [source] is the herb of grass Herba Phaenospermatis globosae Phaenosperma globl sa Munro ex Benth..Gather summer and autumn, cleans, and dries.The spleen invigorating of [function cures mainly] tonify deficiency; Promoting blood flow to regulate menstruation.Main body void after being ill; Amenorrhea.
Mountain Herba rutae [source] is herb or the root of bloodroot great Ye Herba corydalis edulis Corydalis temullfolia Franch..Spring, summer are adopted herb, and uproot autumn, clean, and dry or using fresh herb.[function cures mainly] promoting blood circulation and stopping pain; Heat-clearing and toxic substances removing.Main impairment caused by overstrain; The twinge of breast gastral cavity; Furunculosis of the buttock.
Hyssopus officinalis [source] is the herb of labiate Hyssopus cuspidatus Boriss Hyssopus cuspidatus Boriss..The herb of gathering the 7-8 month; Dry.[function cures mainly] heat clearing away is oestrused; Preventing phlegm from forming and stopping coughing.Main cold, fever; Phlegm-heat cough.
Radix Callicarpae Bodinieri [source] is dicotyledon medicine Verbenaceae Folium Callicarpae Formosanae Callicar bodinieri Levl.[C.giral-diana Hose var.subeanescens Rehd.; C.bodinieri Levl.var.gi-raldii auct.non (Rehd.) Rehd.] root, stem and leaf.Summer, autumn gather, and section is dried or dried.The hemostasis of [function cures mainly] dissipating blood stasis; Expelling wind and removing dampness; Removing toxic substances and promoting subsidence of swelling.Main dysmenorrhea due to blood stasis; Epistaxis; Spitting of blood; Spit blood; Metrorrhagia; Hematuria; Rheumatic arthralgia; Traumatic injury congestive edema; Traumatic hemorrhage; Scald; Erysipelas.
The Herba Blumeae Laciniatae [source] is feverfew six ear bell Blumea laciniata (Roxb.) DC.[Conyza laciniata Roxb.; B.sinuata auct.Non (Loru.) Merr.] herb.All can gather the whole year, and using fresh herb or cutting, dry.[function cures mainly] expelling wind and removing dampness; Removing obstruction in the collateral to relieve pain.Main Common Cold; Wind syndrome of head headache; Anemofrigid-damp arthralgia; Joint aches; Traumatic injury; Carbuncle furuncle; Eczema; Snakebite.
Herba Clinopodii Polycephali [source] is labiate Herba Clinopodii Polycephali Clisnopodium chinense (Benth.) O.Kuntze[Calamintha chinensis Benth.] herb.Summer, autumn gather, and clean, and cutting, dries or using fresh herb.[function cures mainly] wind and heat dispersing; Removing toxic substances and promoting subsidence of swelling; Hemostasis.Main cold, fever; Heatstroke; Laryngopharynx swelling and pain; Diphtheria; Acute cholecystitis; Hepatitis; Intestinal inflammation; Dysentery inflammation; Dysentery; Rib adenitis; Mastitis; Furuncle swelling toxin; Allergic dermatitis; Acute conjunctivitis; Hematuria; Metrorrhagia; Gingival hemorrhage; Traumatic hemorrhage.
Total shape Radix Inulae [source] is the root of the total shape Radix Inulae of feverfew Inula racemosa Hook.f..At the beginning of spring, uproot with autumn end, remove residual stem, section, dries.[function cures mainly] invigorating the spleen and regulating the stomach, promoting the flow of QI for relieving the stagnancy, pain relieving is antiabortive.Have a pain for the breast side of body, gastral cavity abdomen, vomiting dysentery, the breast side of body is dampened, and feels a pain in the chest when breathing and has a pain, frequent fetal movement.
Herba Pogostemonis [source] is labiate Herba Pogostemonis Microtoena insuavis (Hance) Prain ex Dunn[Gomphostemma insuave Hance] herb.Gather complete stroke in summer, autumn, dry or using fresh herb.[function cures mainly] expelling wind and cold; Warming middle-JIAO is regulated the flow of vital energy.Main anemofrigid cold; Cough with asthma is out of breath; Abdominal distention; Dyspepsia; Dysentery stomachache; The whole body is numb; Traumatic injury.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of chronic obstructive pulmonary disease, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing chronic obstructive pulmonary disease.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of chronic obstructive pulmonary disease, it is characterized in that, be prepared from by the medical material of following weight proportion: 5 parts of Herba Clerodendri fortunati, 25 parts of Fructus pterocaryae stnopteraes, 15 parts of Radix Ranunculi Ternatis, 5 parts of adenostemma laveniaKuntzes, 15 parts of Herba Phaenospermatis globosaes, 10 parts of mountain Herba rutaes, 9 parts of Hyssopus officinalis, 15 parts of Radix Callicarpae Bodinieri, 30 parts of the Herba Blumeae Laciniataes, 15 parts of Herba Clinopodii Polycephalis, 5 parts of total shape Radix Inulaes, 15 parts of Herba Pogostemonis.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
According to the COPD diagnostic criteria of " Chinese COPD and asthma diagnosis and treatment guide ", 86 routine COPD patients are collected, age 45-60 year, course of disease 2-10 between year February altogether in inventor in March, 2011-2012.Be divided at random: treatment group 46 examples, male 22 examples, female's 24 examples; Matched group 40 examples, male 19 examples, female's 21 examples.The data there was no significant differences such as two groups of ages, the state of an illness, have comparability.
2, test method
The capsule that the oral the present invention of 2.1 treatment group makes according to specific embodiment 1, sooner or later respectively once.4 weeks courses for the treatment of.
The oral LINGGUI KECHUANNING JIAONANG of 2.2 matched group (pharmaceutcal corporation, Ltd benefits mankind), one time 5,3 times/day.4 weeks courses for the treatment of.(note: other medicine of stopping using in principle during two groups of treatments, patient that can not be inactive for indivedual long-term taking aminophylline class medicines, with low maintenance dose)
3, efficacy determination and therapeutic outcome
Draft with reference to chronic bronchitis curative effect determinate standard.
3.1 individual event symptom curative effect judgements
Clinic control: cough, not enough slight after expectorant, the treatment of breathing heavily, breathe hard.Effective: after above-mentioned individual event symptom treatment, to improve more than 2/3; Take a turn for the better: above-mentioned individual event symptom treatment improves more than 1/3; Invalid: after each individual event symptom treatment, to improve less than 1/3.
3.2 comprehensive therapeutic effect standards
Clinic control: in 4 primary symptoms, 3 clinic control, another 1 effective, double disease alleviates completely; Effective: in 4 primary symptoms 3 effective, 1 is taken a turn for the better or 2 primary symptom clinic control, 2 effective or take a turn for the better, the disease of holding concurrently is obviously improved or takes a turn for the better; Take a turn for the better: do not possess clinic control, effective and invalid condition person; Invalid: only 1 improvement in 4 primary symptoms, or all without taking a turn for the better, or have the severe one of adding.
3.2 treatment statistical results are in table 1 and table 2
Table 1 liang group comprehensive therapeutic effect comparison
Group n Clinic control Effective Take a turn for the better Invalid Total effective rate (%)
Treatment group 46 5(10.9%) 21(45.7%) 16(34.8%) 4(8.7%) 91.4%
Matched group 40 3(7.5%) 18(45.0%) 12(30.0%) 7(17.5%) 82.5%
A table 2 liang group cardinal symptom is improved relatively
Figure BSA0000102444050000031
Visible, the medicine that the present invention makes can safe and effective treatment chronic obstructive pulmonary disease.
Detailed description of the invention
In order to understand better and to implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: 5 grams of Herba Clerodendri fortunati, 25 grams of Fructus pterocaryae stnopteraes, 15 grams of Radix Ranunculi Ternatis, 5 grams of adenostemma laveniaKuntzes, 15 grams of Herba Phaenospermatis globosaes, 10 grams of mountain Herba rutaes, 9 grams of Hyssopus officinalis, 15 grams of Radix Callicarpae Bodinieri, 30 grams of the Herba Blumeae Laciniataes, 15 grams of Herba Clinopodii Polycephalis, 5 grams of total shape Radix Inulaes, 15 grams of Herba Pogostemonis, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, must meet the capsule of 1 day consumption of normal adult.
Be used for the treatment of chronic obstructive pulmonary disease.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: 5 grams of Herba Clerodendri fortunati, 25 grams of Fructus pterocaryae stnopteraes, 15 grams of Radix Ranunculi Ternatis, 5 grams of adenostemma laveniaKuntzes, 15 grams of Herba Phaenospermatis globosaes, 10 grams of mountain Herba rutaes, 9 grams of Hyssopus officinalis, 15 grams of Radix Callicarpae Bodinieri, 30 grams of the Herba Blumeae Laciniataes, 15 grams of Herba Clinopodii Polycephalis, 5 grams of total shape Radix Inulaes, 15 grams of Herba Pogostemonis, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, must meet the powder of 1 day consumption of normal adult.
Be used for the treatment of chronic obstructive pulmonary disease.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: 5 grams of Herba Clerodendri fortunati, 25 grams of Fructus pterocaryae stnopteraes, 15 grams of Radix Ranunculi Ternatis, 5 grams of adenostemma laveniaKuntzes, 15 grams of Herba Phaenospermatis globosaes, 10 grams of mountain Herba rutaes, 9 grams of Hyssopus officinalis, 15 grams of Radix Callicarpae Bodinieri, 30 grams of the Herba Blumeae Laciniataes, 15 grams of Herba Clinopodii Polycephalis, 5 grams of total shape Radix Inulaes, 15 grams of Herba Pogostemonis, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, and to granulate according to this area common process, packaging, can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of chronic obstructive pulmonary disease.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. treat the Chinese medicine of chronic obstructive pulmonary disease for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: 5 parts of Herba Clerodendri fortunati, 25 parts of Fructus pterocaryae stnopteraes, 15 parts of Radix Ranunculi Ternatis, 5 parts of adenostemma laveniaKuntzes, 15 parts of Herba Phaenospermatis globosaes, 10 parts of mountain Herba rutaes, 9 parts of Hyssopus officinalis, 15 parts of Radix Callicarpae Bodinieri, 30 parts of the Herba Blumeae Laciniataes, 15 parts of Herba Clinopodii Polycephalis, 5 parts of total shape Radix Inulaes, 15 parts of Herba Pogostemonis.
CN201410120958.4A 2014-03-20 2014-03-20 Traditional Chinese medicine for treating chronic obstructive pulmonary disease Pending CN103893591A (en)

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Publication number Priority date Publication date Assignee Title
CN111297986A (en) * 2019-12-23 2020-06-19 新疆维吾尔医学专科学校 Vitamin medicinal material composition and preparation method and application thereof

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* Cited by examiner, † Cited by third party
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CN111297986A (en) * 2019-12-23 2020-06-19 新疆维吾尔医学专科学校 Vitamin medicinal material composition and preparation method and application thereof

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