CN106913702A - It is a kind of to treat medicine of interstitial keratitis and preparation method thereof - Google Patents

Abstract

Medicine of interstitial keratitis and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by cicada slough, Radix Codonopsis, date, honeysuckle, cassia seed, dried orange peel, selfheal, levisticum, radix bupleuri, the shell of seaear, the seed of feather cockscomb, the Radix Astragali, butterflybush flower, the bighead atractylodes rhizome, radix scrophulariae, dandelion, tribulus terrestris, scouring rush, Radix Isatidis, Radix Glycyrrhizae, Poria cocos, medicine of the present invention has wind-dispelling heat, clearing away the liver-fire, improving eyesight, cool blood, tonifying middle-Jiao and Qi, calming the liver function, for treating interstitial keratitis instant effect, good effect, do not recur.

Description

It is a kind of to treat medicine of interstitial keratitis and preparation method thereof

Technical field

Medicine of interstitial keratitis and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.

Background technology

Interstitial keratitis is a kind of deep layer diffusivity Corneal inflammation caused by congenital syphilis.From cornea deep layer in a piece of It is principal character that canescence such as ground-glass-like is muddy.It is more common in 5 ~ 20 years old teenager, eyes simultaneously or first sequela, pass through by the course of disease Slowly, can often be faded by several months treatment, prognosis is preferable, but majority leaves scar and hinders eyesight.The traditional Chinese medical science is then Think interstitial keratitis and liver and gall heated, wind-heat of liver channel, liver-blood deficiency is relevant.Because western medicine side effect is big, therefore people To effectively treatment interstitial keratitis Chinese medicine there is great demand, up to now, it has not been found that on this hair Bright relevant report.

The content of the invention

The present inventor have found effectively treatment essence finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science The medicine of property keratitis, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment interstitial keratitis.

Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.

Medicine of the present invention is selection cicada slough, Radix Codonopsis, date, honeysuckle, cassia seed, dried orange peel, selfheal, levisticum, radix bupleuri, stone Cassia, the seed of feather cockscomb, the Radix Astragali, butterflybush flower, the bighead atractylodes rhizome, radix scrophulariae, dandelion, tribulus terrestris, scouring rush, Radix Isatidis, Radix Glycyrrhizae, Poria cocos, schizonepeta, tangerine Stalk, chrysanthemum are combined preparation, these drug regimens are caused into each efficacy of drugs produces synergy such that it is able to effectively control Treat interstitial keratitis.Wherein from cicada slough because its property sweet-salty, cool, enter lung, Liver Channel, there is dissipate wind-heat, facilitaing lung determines convulsion Function, controls affection of exogenous wind-heat, and cough sound is mute, measles without adequate eruption, rubella itch, little Jing Epilepsy, hot eyes, ocular, and furuncle swelling toxin breaks Cold.From Radix Codonopsis because its nature and flavor is sweet, put down, start with, meridian of Foot-TAI YIN qi leel, there is tonifying middle-Jiao and Qi, the function of promoting the production of body fluid controls taste Weakness, qi-blood deficiency, body is tired powerless, and deficiency of food is thirsty, chronic diarrhea, prolapse of the anus.From date because its nature and flavor is sweet, temperature enters spleen, stomach Through, there are tonifying spleen and stomach, nourishing generate fluid adjusts battalion to defend, and the function of antidote poison controls stomach void deficiency of food, and the weak loose stool of spleen, qi-blood-body fluid is not enough, It is disharmony between ying and wei, palpitation and severe palpitation, hysteria of womam.From honeysuckle because its nature and flavor is sweet, tremble with fear, enter lung, stomach, there is heat-clearing, detoxify Function, control warm disease heating, toxic-heat and blood stasis, large carbuncle, pyogenic infections, scrofula, anal fistula.From cassia seed because its nature and flavor bitter sweet, cool, Enter liver and kidney channel, there is clearing liver, improving eyesight, Li Shui, the function of defaecation controls wind-heat cute conjunctivitis, glaucoma, night blindness, hypertension, hepatitis, cirrhosis Abdomen, habitual constipation.From dried orange peel because its is bitter in taste, pungent, temperature, return lung, the spleen channel have regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm Function, controls chest gastral cavity turgor, and deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.From selfheal because its nature and flavor toil, trembles with fear, enter liver, gallbladder channel have Clear liver, the function of dissipating bind controls scrofula, and goiter and tumor, acute mastitis, breast cancer, mesh pearl nyctalgia, photophobia is shed tears, vertigo, facial paralysis, muscle Bone pain, pulmonary tuberculosis, acute icteric catarrhal jaundice, metrorrhagia, under band.From levisticum because its nature and flavor is arduous, temperature enters Kidney, bladder warp, there is a wind-dispelling, win wet, cold dispelling, the function of analgesic, control wind-cold-dampness arthralgia, waist urushic acid bitterly, trick contraction bitterly, Chronic Airway Inflammation, headache, dentalgia.It is cool from radix bupleuri because its is bitter in taste, enter liver, gallbladder channel, have with inducing diaphoresis, soothing the liver, the function of rising Yang, Fevers and chills alternate is controlled, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis.From stone Cassia is put down because its nature and flavor is salty, enters liver and kidney channel, there is calming the liver, and except heat, the function of improving eyesight is controlled wind-yang and up-boring, had a headache dizzy It is dizzy, frightened to jerk, hectic fever due to yin labor heat, optic atrophy.It is cool from the seed of feather cockscomb because its is bitter in taste, enter Liver Channel, there are wind-dispelling heat, clearing away the liver-fire Function, control red eye, swell pain, hide from view, hypertension, nosebleed epistaxis, skin wind-heat itch, scabies leprosy.From the Radix Astragali because its nature and flavor is sweet, Tepor, enters lung, the spleen channel, raw to defend solid table with beneficial, inducing diuresis for removing edema, eliminating toxic, the function of myogenic, controls spontaneous perspiration, night sweat, blood-arthralgia, edema, Ulcer is not burst or is burst and holds back long；Process with the function of having bowl spares benefit, control internal injury overstrain, splenasthenic diarrhea, prolapse of the anus, deficiency of vital energy blood takes off, collapse band and The disease of all laboured breathing deficiency of blood.It is cool from butterflybush flower because its nature and flavor is sweet, enter Liver Channel, there is wind-dispelling, cool blood moistens liver, the work(of improving eyesight Can, control red eye, swell pain, many tear photophobia, glaucoma ocular, the rotten eye of wind string.From the bighead atractylodes rhizome because its nature and flavor bitter sweet, temperature, enter spleen, stomach Through, have a tonifying spleen, beneficial stomach, eliminating dampness, and in function, control deficient QI of the spleen and stomach, do not feel like eating, the few gas of burnout, empty swollen, diarrhea, phlegm and retained fluid, water Swollen, jaundice, arthritis with fixed pain caused by dampness, difficult urination is dizzy, and spontaneous perspiration, nausea is uneasy.It is salty from radix scrophulariae because its is bitter in taste, it is cool, enter lung, kidney Through, there is enriching yin, fall fire, relieving restlessness, the function of removing toxic substances controls pyreticosis polydipsia, sends out spot, hectic fever due to yin labor heat, and night sleeps not peaceful, spontaneous sweating, Tianjin Hinder constipation, hematemesis and epistaxis, abscess of throat, carbuncle swells, scrofula.From dandelion because its nature and flavor bitter sweet, trembles with fear, enter liver, stomach have Clearing heat and detoxicating, the function of diuresis dissipating bind controls acute mastitis, adenolymphitis, scrofula, malignant boil carbuncle toxin, acute conjunctivitis, flu hair Heat, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infections.From tribulus terrestris because its nature and flavor Toil, temperature, enter liver, lung channel have scattered wind, and improving eyesight, lower gas, the function of promoting circulation of blood controls headache, and body is itched, and hot eyes swells screen, fullness sensation in chest, cough it is inverse, Disorder lumps in the abdomen, breast is difficult, ulcer, scrofula.From scouring rush because its nature and flavor sweetness and bitterness, put down, enter lung, liver, gallbladder channel, there is a wind-dispelling heat-dissipating, expelling pathogenic factors from muscles and skin, The function of screen is moved back, mesh life cloudiness, tearing against wind, discharging fresh blood stool, bloody flux, prolapse of the anus, malaria, laryngalgia, carbuncle swells is controlled.It is from Radix Isatidis Because its is bitter in taste, tremble with fear, enter liver, stomach blood system have heat-clearing, removing toxic substances, the function of cool blood controls influenza, and epidemic meningitis, encephalitis, pneumonia is red Poison, heat toxin hair spot, coma hematemesis, pharynx swelling, mumps, pinkeye, sore rash.From Radix Glycyrrhizae because its property sweet taste, enters spleen, stomach, lung Through, have and process, deficiency of food weakness of the spleen and the stomach with controlling with middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription, loose stool of suffering from abdominal pain, overstrain heating, Consumptive lung disease is coughed, palpitaition, shies carbuncle, raw with controlling abscess of throat, peptic ulcer, ulcer sores, antidote poison and is poisoned by food.From Fu Siberian cocklebur is put down because its property slightly sweet flavor, enters the heart, spleen, lung channel, there is eliminating dampness and diuresis, and beneficial spleen and stomach, the function of antitoxic heart-soothing and sedative controls urine Unfavorable oedema distending pain, phlegm and retained fluid coughs inverse, the sound of vomiting of vomitting, and diarrhea, seminal emission, stranguria with turbid discharge, palpitation with fear is forgetful.From schizonepeta because its nature and flavor is pungent, Temperature, enters lung, Liver Channel, delivers, wind-dispelling, the function of regulating blood condition, fries charcoal hemostasis, and cure cold heating, headache, abscess of throat, middle air port Keep silent, spit blood, bleeding from five sense organs or subcutaneous tissue is had blood in stool, uterine bleeding, postpartum anemic fainting, carbuncle swells, sore scabies, scrofula.From balloonflower root because its nature and flavor toil, puts down, enter Lung, stomach, there is out facilitaing lung gas, and the function of eliminating the phlegm apocenosis controls exogenous cough, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery Stomachache.From chrysanthemum because its nature and flavor sweetness and bitterness, cool, enter lung, Liver Channel has dispelling wind, and disappear heat, improving eyesight, the function of removing toxic substances controls head Bitterly, dizziness, hot eyes, ambition dysphoria with smothery sensation, furunculosis, pyogenic infections.

Specific embodiment

The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount：

15-25 grams of cicada slough, 10-15 grams of Radix Codonopsis, 5-15 grams of date, 25-35 grams of honeysuckle, 15-25 grams of cassia seed, dried orange peel 5-10 Gram, 5-15 grams of selfheal, 5-10 grams of levisticum, 5-15 grams of radix bupleuri, 10-20 grams of the shell of seaear, 10-20 grams of the seed of feather cockscomb, Radix Astragali 10-15 Gram, 15-20 grams of butterflybush flower, 5-15 grams of the bighead atractylodes rhizome, 5-15 grams of radix scrophulariae, 10-15 grams of dandelion, 5-15 grams of tribulus terrestris, 5-15 grams of scouring rush, 10-20 grams of Radix Isatidis, 5-15 grams of Radix Glycyrrhizae, 10-15 grams of Poria cocos, 10-20 grams of schizonepeta, 5-15 grams of balloonflower root, 10-15 grams of chrysanthemum.

Preferably：

20 grams of cicada slough, 12 grams of Radix Codonopsis, 10 grams of date, 30 grams of honeysuckle, 20 grams of cassia seed, 8 grams of dried orange peel, 10 grams of selfheal, levisticum 8 Gram, 10 grams of radix bupleuri, 15 grams of the shell of seaear, 15 grams of the seed of feather cockscomb, 12 grams of the Radix Astragali, 18 grams of butterflybush flower, 10 grams of the bighead atractylodes rhizome, 10 grams of radix scrophulariae, Pu Gong 12 grams of English, 10 grams of tribulus terrestris, 10 grams of scouring rush, 15 grams of Radix Isatidis, 10 grams of Radix Glycyrrhizae, 12 grams of Poria cocos, 15 grams of schizonepeta, 10 grams of balloonflower root, chrysanthemum Spend 12 grams.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, cicada slough：Impurity is picked, is cleaned and is dried；

2nd, Radix Codonopsis：Reed, section or segment are run through after cleaning silt, is dried；

3rd, date：Net impurity is picked, is dried；

4th, honeysuckle：Silt is weeded out, net impurity is picked；

5th, cassia seed：Net cassia seed is taken, to put fried in pot to micro- has fragrance, takes out, and cools；

6th, dried orange peel：Crude drug is taken, the pericarp of impurity and blackening is removed, wash quickly is net, softens, chopping, dries or low temperature drying, sieves Dedusting is considered to be worth doing；

7th, selfheal：Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out；

8th, levisticum：Impurity is picked, size is separated, cleaned, cut into slices after running through, dried；

9th, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through；

10th, the shell of seaear：Clean and dry, knock fragment；

11st, the seed of feather cockscomb：Crude drug is taken, impurity is removed, grey bits are weeded out；

12nd, the Radix Astragali：Net impurity is picked, the root head and hollow the greater of residual is removed, is soaked in water, pulled out, section in time after running through, Dry；

13rd, butterflybush flower：Pick impurity, well sifted dirt；

14th, the bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

15th, radix scrophulariae：Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried；

16th, dandelion：Impurity is picked, soil is cleaned, segment is dried；

17th, tribulus terrestris：Silt, the hard thorn of cleared residual are removed in drift；

18th, scouring rush：Clean, slightly moisten, cut off root, segment is dried；

19th, Radix Isatidis：Net impurity is picked, is cleaned, run through, cut into slices, dried；

20th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing；

21st, Poria cocos：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；

22nd, schizonepeta：Net impurity is picked, is slightly steeped with water, pull segment out, dried；

23rd, balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；

24th, chrysanthemum：Pick net leaf stalk, anthocaulus and spare impurity.

2nd, prepare

1st, by the cicada slough after processing, Radix Codonopsis, date, honeysuckle, cassia seed, dried orange peel, selfheal, levisticum, radix bupleuri, the shell of seaear, green grass or young crops Feather cockscomb, the Radix Astragali, butterflybush flower, the bighead atractylodes rhizome, radix scrophulariae, dandelion, tribulus terrestris, scouring rush, Radix Isatidis, Radix Glycyrrhizae, Poria cocos, schizonepeta, balloonflower root, chrysanthemum It is put into decocting container, adds water for the first time 6 times and measure, after immersion 100 minutes, fries by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, First time decoction liquor is filtered to obtain, first time decoction liquor is poured into container；

2nd, the dregs of a decoction of filtering are added water 5 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

3rd, will decoction liquor mixing and stirring twice, be divided into 2 doses and take.

The seed of feather cockscomb has wind-dispelling heat in prescription, and the function of clearing away the liver-fire is monarch drug in a prescription；Cassia seed clears liver, improving eyesight, Li Shui；Butterflybush flower has Wind-dispelling, cool blood, profit liver, the function of improving eyesight, the two is ministerial drug, and three taste medicines play wind-dispelling heat, clearing away the liver-fire, improving eyesight, cool blood, profit jointly The effect of liver, treatment interstitial keratitis effect is comprehensive, and hot with wind-dispelling, clearing away the liver-fire, improving eyesight, can be effected a permanent cure based on cool blood, Radix Codonopsis There is tonifying middle-Jiao and Qi, the function of promoting the production of body fluid is adjutant, and the shell of seaear has calming the liver, except heat, the function of improving eyesight is to make medicine, with remaining all medicines It is to take stopgap measures.

Medicine of the present invention has wind-dispelling heat, clearing away the liver-fire, improving eyesight, cool blood, tonifying middle-Jiao and Qi, calming the liver function, for controlling Treat interstitial keratitis, short treating period, instant effect, non-relapse after healing.

The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include this hair The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and every group 15, one of which is tested for overdose Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, takes medicine continuously 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, physical data

Accept interstitial keratitis out-patient totally 13 for medical treatment.

2nd, diagnostic criteria

Classical symptom mixes the heavier companioned with headache of red, pain or eye socket distending pain, bitter taste in the mouth and dry throat, photophobia to suffer from eye, sheds tears, pain, depending on thing It is fuzzy.

3rd, treatment method

From above-mentioned medicament, taken to patient, each take 1 dose, early daily, evening respectively takes 1 time, be within 7 days a course for the treatment of, continuous clothes With 3 courses for the treatment of.

4th, efficacy assessment standard

It is effective：Interstitial keratitis symptom disappears, and recovers normal, recovery from illness；

Take a turn for the better：Patient suffers from eye and mixes red, and eye socket distending pain, bitter taste in the mouth and dry throat, photophobia is shed tears, pain, the symptom mitigation of blurred vision, real Matter keratitis symptom is clearly better, and progressively recovers normal；

It is invalid：Improvement standard person is not reached.

5th, treatment results（See the table below）

In above-mentioned treatment, with drug therapy interstitial keratitis patient 13 of the present invention, as a result effective 10, obvious effective rate is 76.92%, take a turn for the better 2, improvement rate is 15.38%, and invalid 1, total effective rate is 92.3%.

Claims (3)

1. a kind of medicine for treating interstitial keratitis, it is characterised in that：It is made up of the bulk drug in following weight range：

15-25 grams of cicada slough, 10-15 grams of Radix Codonopsis, 5-15 grams of date, 25-35 grams of honeysuckle, 15-25 grams of cassia seed, dried orange peel 5-10 Gram, 5-15 grams of selfheal, 5-10 grams of levisticum, 5-15 grams of radix bupleuri, 10-20 grams of the shell of seaear, 10-20 grams of the seed of feather cockscomb, Radix Astragali 10-15 Gram, 15-20 grams of butterflybush flower, 5-15 grams of the bighead atractylodes rhizome, 5-15 grams of radix scrophulariae, 10-15 grams of dandelion, 5-15 grams of tribulus terrestris, 5-15 grams of scouring rush, 10-20 grams of Radix Isatidis, 5-15 grams of Radix Glycyrrhizae, 10-15 grams of Poria cocos, 10-20 grams of schizonepeta, 5-15 grams of balloonflower root, 10-15 grams of chrysanthemum.

2. medicine according to claim 1, wherein the consumption of each bulk drug is：

20 grams of cicada slough, 12 grams of Radix Codonopsis, 10 grams of date, 30 grams of honeysuckle, 20 grams of cassia seed, 8 grams of dried orange peel, 10 grams of selfheal, levisticum 8 Gram, 10 grams of radix bupleuri, 15 grams of the shell of seaear, 15 grams of the seed of feather cockscomb, 12 grams of the Radix Astragali, 18 grams of butterflybush flower, 10 grams of the bighead atractylodes rhizome, 10 grams of radix scrophulariae, Pu Gong 12 grams of English, 10 grams of tribulus terrestris, 10 grams of scouring rush, 15 grams of Radix Isatidis, 10 grams of Radix Glycyrrhizae, 12 grams of Poria cocos, 15 grams of schizonepeta, 10 grams of balloonflower root, chrysanthemum Spend 12 grams.

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Cicada slough：Impurity is picked, is cleaned and is dried；

（2）Radix Codonopsis：Reed, section or segment are run through after cleaning silt, is dried；

（3）Date：Net impurity is picked, is dried；

（4）Honeysuckle：Silt is weeded out, net impurity is picked；

（5）Cassia seed：Net cassia seed is taken, to put fried in pot to micro- has fragrance, takes out, and cools；

（6）Dried orange peel：Crude drug is taken, the pericarp of impurity and blackening is removed, wash quickly is net, softens, chopping, dries or low temperature drying, Weed out grey bits；

（7）Selfheal：Crude drug is taken, except discarding stalk, blade and impurity, grey bits is weeded out；

（8）Levisticum：Impurity is picked, size is separated, cleaned, cut into slices after running through, dried；

（9）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, pulled out, section in time, dries immediately after running through；

（10）The shell of seaear：Clean and dry, knock fragment；

（11）The seed of feather cockscomb：Crude drug is taken, impurity is removed, grey bits are weeded out；

（12）The Radix Astragali：Net impurity is picked, the root head and hollow the greater of residual is removed, is soaked in water, pulled out, cut in time after running through Piece, dries；

（13）Butterflybush flower：Pick impurity, well sifted dirt；

（14）The bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

（15）Radix scrophulariae：Net impurity is picked, except removing LU, is cleaned and is run through, cut into slices, dried；

（16）Dandelion：Impurity is picked, soil is cleaned, segment is dried；

（17）Tribulus terrestris：Silt, the hard thorn of cleared residual are removed in drift；

（18）Scouring rush：Clean, slightly moisten, cut off root, segment is dried；

（19）Radix Isatidis：Net impurity is picked, is cleaned, run through, cut into slices, dried；

（20）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing；

（21）Poria cocos：Be soaked in water, clean pull out, it is vexed after, cut into slices, dry；

（22）Schizonepeta：Net impurity is picked, is slightly steeped with water, pull segment out, dried；

（23）Balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；

（24）Chrysanthemum：Pick net leaf stalk, anthocaulus and spare impurity；

（Two）Prepare

（1）By the cicada slough after processing, Radix Codonopsis, date, honeysuckle, cassia seed, dried orange peel, selfheal, levisticum, radix bupleuri, the shell of seaear, green grass or young crops Feather cockscomb, the Radix Astragali, butterflybush flower, the bighead atractylodes rhizome, radix scrophulariae, dandelion, tribulus terrestris, scouring rush, Radix Isatidis, Radix Glycyrrhizae, Poria cocos, schizonepeta, balloonflower root, chrysanthemum It is put into decocting container, adds water 6 times and measure, after soaking 100 minutes, fries by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter First time decoction liquor, first time decoction liquor is poured into container；

（2）The dregs of a decoction of filtering are added water 5 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 2 doses and is taken.