CN106892811B - 一种苯甲酸纯化方法 - Google Patents
一种苯甲酸纯化方法 Download PDFInfo
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- CN106892811B CN106892811B CN201710127933.0A CN201710127933A CN106892811B CN 106892811 B CN106892811 B CN 106892811B CN 201710127933 A CN201710127933 A CN 201710127933A CN 106892811 B CN106892811 B CN 106892811B
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- CN
- China
- Prior art keywords
- benzoic acid
- kettle
- formic acid
- crude benzol
- acid solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 title claims abstract description 163
- 239000005711 Benzoic acid Substances 0.000 title claims abstract description 80
- 235000010233 benzoic acid Nutrition 0.000 title claims abstract description 80
- 238000000746 purification Methods 0.000 title claims abstract description 16
- IMXLQXHCHYKEEE-UHFFFAOYSA-N benzene;formic acid Chemical compound OC=O.C1=CC=CC=C1 IMXLQXHCHYKEEE-UHFFFAOYSA-N 0.000 claims abstract description 34
- 238000002425 crystallisation Methods 0.000 claims abstract description 29
- 230000008025 crystallization Effects 0.000 claims abstract description 28
- 238000006243 chemical reaction Methods 0.000 claims abstract description 20
- 239000007788 liquid Substances 0.000 claims abstract description 15
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 9
- 239000008367 deionised water Substances 0.000 claims abstract description 6
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 6
- 239000012535 impurity Substances 0.000 claims description 14
- 238000002844 melting Methods 0.000 claims description 13
- 230000008018 melting Effects 0.000 claims description 13
- 238000000926 separation method Methods 0.000 claims description 9
- 239000013078 crystal Substances 0.000 claims description 6
- 238000001704 evaporation Methods 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 5
- 150000002148 esters Chemical class 0.000 claims description 3
- 230000008020 evaporation Effects 0.000 claims description 3
- 239000003610 charcoal Substances 0.000 claims description 2
- 238000001816 cooling Methods 0.000 claims description 2
- 238000012545 processing Methods 0.000 claims description 2
- 229960004365 benzoic acid Drugs 0.000 abstract description 71
- 238000000034 method Methods 0.000 abstract description 20
- 238000004519 manufacturing process Methods 0.000 abstract description 15
- 239000000356 contaminant Substances 0.000 abstract description 2
- 239000007787 solid Substances 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 abstract description 2
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 12
- 239000000047 product Substances 0.000 description 9
- 238000009835 boiling Methods 0.000 description 6
- 238000001914 filtration Methods 0.000 description 5
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- MTZQAGJQAFMTAQ-UHFFFAOYSA-N ethyl benzoate Chemical compound CCOC(=O)C1=CC=CC=C1 MTZQAGJQAFMTAQ-UHFFFAOYSA-N 0.000 description 4
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 4
- 238000005457 optimization Methods 0.000 description 4
- 230000003647 oxidation Effects 0.000 description 3
- 238000007254 oxidation reaction Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000002351 wastewater Substances 0.000 description 3
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- VEVJTUNLALKRNO-TYHXJLICSA-N benzoyl-CoA Chemical compound O=C([C@H](O)C(C)(COP(O)(=O)OP(O)(=O)OC[C@@H]1[C@H]([C@@H](O)[C@@H](O1)N1C2=NC=NC(N)=C2N=C1)OP(O)(O)=O)C)NCCC(=O)NCCSC(=O)C1=CC=CC=C1 VEVJTUNLALKRNO-TYHXJLICSA-N 0.000 description 2
- 238000004061 bleaching Methods 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 235000019253 formic acid Nutrition 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- 239000005457 ice water Substances 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000155 melt Substances 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 description 2
- XNGIFLGASWRNHJ-UHFFFAOYSA-N phthalic acid Chemical compound OC(=O)C1=CC=CC=C1C(O)=O XNGIFLGASWRNHJ-UHFFFAOYSA-N 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 2
- 235000010234 sodium benzoate Nutrition 0.000 description 2
- 239000004299 sodium benzoate Substances 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241001478240 Coccus Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 238000006114 decarboxylation reaction Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 239000011344 liquid material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000001937 non-anti-biotic effect Effects 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Crystallography & Structural Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Description
Claims (5)
Priority Applications (1)
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CN201710127933.0A CN106892811B (zh) | 2017-03-06 | 2017-03-06 | 一种苯甲酸纯化方法 |
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CN201710127933.0A CN106892811B (zh) | 2017-03-06 | 2017-03-06 | 一种苯甲酸纯化方法 |
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CN106892811A CN106892811A (zh) | 2017-06-27 |
CN106892811B true CN106892811B (zh) | 2019-06-14 |
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CN201710127933.0A Active CN106892811B (zh) | 2017-03-06 | 2017-03-06 | 一种苯甲酸纯化方法 |
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CN (1) | CN106892811B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113149833A (zh) * | 2021-03-10 | 2021-07-23 | 武汉海斯普林科技发展有限公司 | 一种烷基苯甲酸的纯化方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL164370B1 (pl) * | 1990-01-03 | 1994-07-29 | Wyzsza Szkola Inzynierska | Sposób oczyszczania kwasu benzoesowego PL |
CN102001935A (zh) * | 2010-11-29 | 2011-04-06 | 武汉有机实业有限公司 | 苯甲酸的精制方法 |
CN102863330A (zh) * | 2012-09-29 | 2013-01-09 | 仪征市茂瑞化工有限公司 | 一种从pta工艺废水分离精制工业苯甲酸的方法 |
KR20140003184A (ko) * | 2012-06-29 | 2014-01-09 | 삼성석유화학(주) | 벤젠디카르복실산 제조공정에서 생성된 부산물로부터 벤조산을 회수하는 방법 |
-
2017
- 2017-03-06 CN CN201710127933.0A patent/CN106892811B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL164370B1 (pl) * | 1990-01-03 | 1994-07-29 | Wyzsza Szkola Inzynierska | Sposób oczyszczania kwasu benzoesowego PL |
CN102001935A (zh) * | 2010-11-29 | 2011-04-06 | 武汉有机实业有限公司 | 苯甲酸的精制方法 |
KR20140003184A (ko) * | 2012-06-29 | 2014-01-09 | 삼성석유화학(주) | 벤젠디카르복실산 제조공정에서 생성된 부산물로부터 벤조산을 회수하는 방법 |
CN102863330A (zh) * | 2012-09-29 | 2013-01-09 | 仪征市茂瑞化工有限公司 | 一种从pta工艺废水分离精制工业苯甲酸的方法 |
Non-Patent Citations (1)
Title |
---|
苯甲酸的合成和精制;吴鑫干等;《现代化工》;20001231;第20卷(第8期);第10-14页 |
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CN106892811A (zh) | 2017-06-27 |
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PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CP03 | Change of name, title or address |
Address after: 277200 No.1, Yinshan Industrial Park, economic development zone, Shanting District, Zaozhuang City, Shandong Province Patentee after: Shandong tongtaiweirun Food Technology Co.,Ltd. Address before: 277200 Shandong city of Zaozhuang province Shanting District City Town waterlogging Stephen East Village Patentee before: SHANDONG PROVINCE AND TAI WEI RUN FOOD TECHNOLOGY Co.,Ltd. |
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CP03 | Change of name, title or address | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A purification method of benzoic acid Effective date of registration: 20210909 Granted publication date: 20190614 Pledgee: Zaozhuang Rural Commercial Bank Co.,Ltd. Shanting sub branch Pledgor: Shandong tongtaiweirun Food Technology Co.,Ltd. Registration number: Y2021980009162 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20220829 Granted publication date: 20190614 Pledgee: Zaozhuang Rural Commercial Bank Co.,Ltd. Shanting sub branch Pledgor: Shandong tongtaiweirun Food Technology Co.,Ltd. Registration number: Y2021980009162 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: A purification method for benzoic acid Granted publication date: 20190614 Pledgee: Zaozhuang rural commercial bank Limited by Share Ltd. Shanting branch Pledgor: Shandong tongtaiweirun Food Technology Co.,Ltd. Registration number: Y2024980000830 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right |