CN106880554A - A kind of sweet wormwood toothpaste and preparation method thereof - Google Patents
A kind of sweet wormwood toothpaste and preparation method thereof Download PDFInfo
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- CN106880554A CN106880554A CN201710150604.8A CN201710150604A CN106880554A CN 106880554 A CN106880554 A CN 106880554A CN 201710150604 A CN201710150604 A CN 201710150604A CN 106880554 A CN106880554 A CN 106880554A
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- sweet wormwood
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- Health & Medical Sciences (AREA)
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Abstract
The present invention relates to household chemicals technical field, in particular to a kind of sweet wormwood toothpaste and preparation method thereof, the sweet wormwood raw material of toothpaste is by weight percentage:Rubbing agent 18~25%, adhesive 0.3~0.6%, NMF 54~64%, foaming agent 2~7%, sweetener 0.05~0.2%, preservative 0.1~0.4%, sodium pyrophosphate 0.3~0.6%, essence 1~2%, qinghaosu or Artesunate 0.1~0.3%, balance of sweet wormwood grass extract the aqueous solution.Sweet wormwood toothpaste of the present invention has sterilization, antibacterial, bacteria resistance function with the fresh sweet wormwood grass extraction aqueous solution with qinghaosu or Artesunate collocation, prevents bleeding gums, and being also added into sodium pyrophosphate has good preventing and treating calculus dentalis and bacterial plaque effect.
Description
Technical field
The present invention relates to household chemicals technical field, in particular to a kind of sweet wormwood toothpaste and preparation method thereof.
Background technology
As the progress and development of society, daily life level are improved constantly, the requirement to details articles for use is also got over
Come higher, using during toothpaste, people are not only required to decontaminate de-sludging, it is also desirable to degerming bacteria resistance function and disappear
Scorching function.
Sweet wormwood, with the effect such as significant antimalarial, anti-inflammatory, while also there is antitumor, anti-lupus erythematosus, anti-schistosome,
Other parasites such as Infection of Toxoplasma Gondii, Pneumocystis carinii, Paragonismus westermani, its derivative sodium artesunate is to golden grape, Fu Shi dysentery
Shigella, Escherichia coli, micrococcus catarrhalis, A type and Bacillus paratyphosus B have certain antibacterial action, while qinghaosu pair
Suppress scar proliferation inhibited.
Because qinghaosu has above-mentioned effect, apply it to can significantly improve in washing product the sterilized of washing product with
Health-care effect, but it is current in the washing product containing Artemisinin is prepared, focus primarily upon qinghaosu and extract and add after refined
The method for entering, and the utilization of other compositions to containing in sweet wormwood is less, causes a large amount of active materials to be wasted.And come at present
See, and have no report of the sweet wormwood class product utilization in the middle of field of toothpaste.
The content of the invention
To solve the above problems, the present invention provides a kind of sweet wormwood toothpaste and preparation method thereof, can effectively sterilization, disappear
Inflammation, the effect for taking care of one's teeth.
To achieve these goals, the technical solution adopted in the present invention is, a kind of sweet wormwood toothpaste, its raw material by weight hundred
Ratio is divided to be calculated as rubbing agent 18~25%, adhesive 0.3~0.6%, NMF 54~64%, foaming agent 2~7%, sweetener
0.05~0.2%, preservative 0.1~0.4%, sodium pyrophosphate 0.3~0.6%, essence 1~2%, qinghaosu or Artesunate 0.1~
0.3%, balance of sweet wormwood grass extracts the aqueous solution.
Described NMF is sorbierite, polyethylene glycol -1450, the mixing of propane diols.
Preferably, a kind of sweet wormwood toothpaste, its raw materials by weight is calculated as silica 1 8~25%, cellulose gum
0.3~0.6%, laruyl alcohol sodium sulfovinate 2~4%, sorbierite 50~55%, polyethylene glycol -1,450 2~4%, propane diols 2~5%,
Sodium Benzoate 0.1~0.4%, saccharin 0.05~0.2%, sodium pyrophosphate 0.3~0.6%, essence 1~2%, qinghaosu or Artesunate
0.1~0.3%, its balance of sweet wormwood grass extracts the aqueous solution.
Further, it is that fresh sweet wormwood is soaked with 85~90 DEG C of deionized water that described sweet wormwood grass extracts the aqueous solution
10~20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:35~45.This solution has stronger
Antibacterial and antiinflammation, can be arranged in pairs or groups with qinghaosu or Artesunate, its antibacterial, bacteriostasis efficacy are further enhanced, while increasing
Plus antibacterial, scope of restraining fungi.
Preferably, fresh sweet wormwood:Deionized water=1:40.
A kind of toothpaste preparation method as described above, comprises the following steps:
A. adhesive is added in the sweet wormwood grass extraction aqueous solution of occupancy 30 ± 3%, stirring and heating is completely dissolved it, standby
With;
B. foaming agent is added in the sweet wormwood grass extraction aqueous solution of occupancy 40 ± 4%, is stirred, it is standby;
C. rubbing agent, sweetener, preservative, sodium pyrophosphate are well mixed, it is standby;
D. qinghaosu or Artesunate are dissolved in NMF, it is standby;
E. step b and step d gained is added in vacuum Manufacturing medicine extract machine, opens vacuum and stirring, after stirring, add step c
Middle gained extracts the aqueous solution with remaining sweet wormwood grass, and essence and step a gained are added after stirring, and after stirring, recovers
To normal pressure, lotion is obtained.
Further, when step b is mixed with step d gained in the step e, vacuum is -0.8MPa, mixing speed
It is 60 ± 4r/min, mixing time is 15~25min.
Further, after adding step c gained to extract the aqueous solution with remaining sweet wormwood grass in the step e, vacuum is -0.95
~-0.85MPa, mixing time is 10~15min.
Further, add step a institute in the step e with essence after, vacuum is -0.85~-0.8MPa, is stirred
Time is 20~25min.
Further, also include being stored in packing step after the step e.
There is advantages below using scheme of the present invention:
1. sweet wormwood toothpaste of the present invention adds qinghaosu or Artesunate.Can effectively antibacterial, sterilization, protection oral cavity defend
It is raw, and with antiinflammation, effectively prevent bleeding gums;
2. formula adds sweet wormwood grass to extract the aqueous solution and replaces conventional deionized water, improves containing for the sweet wormwood active ingredient in toothpaste
Amount, and can be arranged in pairs or groups with qinghaosu or Artesunate, its antibacterial, bacteriostasis efficacy are further enhanced, while increasing antibacterial, antibacterial model
Enclose;
3. adding sodium pyrophosphate has good preventing and treating calculus dentalis and bacterial plaque effect;
4. preparation method is simple, easily operated, and with low cost, preparation continuity, universality are good, significantly reduce production cost,
Significantly improve product quality.
Specific embodiment
The present invention is described in further detail below by specific embodiment.
Embodiment 1:A kind of sweet wormwood toothpaste, its raw materials by weight is calculated as rubbing agent 22%, adhesive 0.5%, protects
Humectant 59%, foaming agent 5%, sweetener 0.12%, preservative 0.25%, sodium pyrophosphate 0.4%, essence 1.5%, qinghaosu 0.1%,
Artesunate 0.2%, balance of sweet wormwood grass extracts the aqueous solution.
Described sweet wormwood grass extract the aqueous solution be fresh sweet wormwood is carried out with 85~90 DEG C of deionized water immersion 10~
20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:40.
A kind of toothpaste preparation method as described above, comprises the following steps:
A. adhesive is added in the sweet wormwood grass extraction aqueous solution of occupancy 30 ± 3%, stirring and heating is completely dissolved it, standby
With;
B. foaming agent is added in the sweet wormwood grass extraction aqueous solution of occupancy 40 ± 4%, is stirred, it is standby;
C. rubbing agent, sweetener, preservative, sodium pyrophosphate are well mixed, it is standby;
D. qinghaosu or Artesunate are dissolved in NMF, it is standby;
E. step b and step d gained is added in vacuum Manufacturing medicine extract machine, opens vacuum and stirring, vacuum is -0.8MPa, stirring
Speed is 60 ± 4r/min, and mixing time is 15~25min, and after stirring, gained is carried with remaining sweet wormwood grass in adding step c
Aqueous, vacuum is -0.95~-0.85MPa, and mixing time is 10~15min, and essence is added after stirring with step
Rapid a gained, vacuum is -0.85~-0.8MPa, and mixing time is 20~25min, after stirring, returns to normal pressure, is obtained
Lotion;
F. the above-mentioned lotion for preparing is put into holding vessel, is dispensed, obtain sweet wormwood tooth paste product.
Embodiment 2:A kind of sweet wormwood toothpaste, its raw materials by weight is calculated as silica 20%, cellulose gum 0.4%,
Laruyl alcohol sodium sulfovinate 3%, sorbierite 52%, polyethylene glycol -1,450 3%, propane diols 3%, Sodium Benzoate 0.3%, saccharin 0.1% is burnt
Sodium phosphate 0.4%, essence 1.8%, qinghaosu 0.15%, Artesunate 0.15%, its balance of sweet wormwood grass extracts the aqueous solution.
Described sweet wormwood grass extract the aqueous solution be fresh sweet wormwood is carried out with 85~90 DEG C of deionized water immersion 10~
20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:40.
A kind of toothpaste preparation method as described above, comprises the following steps:
A. cellulose gum is proportionally added into in 30 ± 3% sweet wormwood grass aqueous solution, stirs and heat that to be completely dissolved it standby
With;
B. laruyl alcohol sodium sulfovinate is added in the sweet wormwood grass extraction aqueous solution of occupancy 40 ± 4%, is stirred, it is standby;
C. silica, saccharin, Sodium Benzoate, sodium pyrophosphate are well mixed, it is standby;
D. qinghaosu and Artesunate are dissolved in the mixing liquid of sorbierite, propane diols, polyethylene glycol, it is standby;
E. step b and step d gained is added in vacuum Manufacturing medicine extract machine, opens vacuum and stirring, vacuum is -0.8MPa, stirring
Speed is 60 ± 4r/min, and mixing time is 15~25min, and after stirring, gained is carried with remaining sweet wormwood grass in adding step c
Aqueous, vacuum is -0.95~-0.85MPa, and mixing time is 10~15min, and essence is added after stirring with step
Rapid a gained, vacuum is -0.85~-0.8MPa, and mixing time is 20~25min, after stirring, returns to normal pressure, is obtained
Lotion;
F. the above-mentioned lotion for preparing is put into holding vessel, is dispensed, obtain sweet wormwood tooth paste product.
Embodiment 3:A kind of sweet wormwood toothpaste, its raw materials by weight is calculated as silica 1 8%, cellulose gum 0.6%,
Laruyl alcohol sodium sulfovinate 4%, sorbierite 55%, polyethylene glycol -1,450 4%, propane diols 5%, Sodium Benzoate 0.1%, saccharin 0.05%,
Sodium pyrophosphate 0.3%, essence 2%, qinghaosu 0.1%, its balance of sweet wormwood grass extracts the aqueous solution.
Described sweet wormwood grass extract the aqueous solution be fresh sweet wormwood is carried out with 85~90 DEG C of deionized water immersion 10~
20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:35.
A kind of toothpaste preparation method as described above, comprises the following steps:
A. cellulose gum is proportionally added into in 30 ± 3% sweet wormwood grass aqueous solution, stirs and heat that to be completely dissolved it standby
With;
B. laruyl alcohol sodium sulfovinate is added in the sweet wormwood grass extraction aqueous solution of occupancy 40 ± 4%, is stirred, it is standby;
C. silica, saccharin, Sodium Benzoate, sodium pyrophosphate are well mixed, it is standby;
D. qinghaosu is dissolved in the mixing liquid of sorbierite, propane diols, polyethylene glycol, it is standby;
E. step b and step d gained is added in vacuum Manufacturing medicine extract machine, opens vacuum and stirring, vacuum is -0.8MPa, stirring
Speed is 60 ± 4r/min, and mixing time is 15~25min, and after stirring, gained is carried with remaining sweet wormwood grass in adding step c
Aqueous, vacuum is -0.95~-0.85MPa, and mixing time is 10~15min, and essence is added after stirring with step
Rapid a gained, vacuum is -0.85~-0.8MPa, and mixing time is 20~25min, after stirring, returns to normal pressure, is obtained
Lotion.
Embodiment 4:A kind of sweet wormwood toothpaste, its raw materials by weight is calculated as silica 25%, cellulose gum 0.3%,
Laruyl alcohol sodium sulfovinate 2%, sorbierite 50%, polyethylene glycol -1,450 2%, propane diols 2%, Sodium Benzoate 0.4%, saccharin 0.2% is burnt
Sodium phosphate 0.6%, essence 1%, Artesunate 0.3%, its balance of sweet wormwood grass extracts the aqueous solution.
Described sweet wormwood grass extract the aqueous solution be fresh sweet wormwood is carried out with 85~90 DEG C of deionized water immersion 10~
20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:35.
A kind of toothpaste preparation method as described above, comprises the following steps:
A. cellulose gum is proportionally added into in 30 ± 3% sweet wormwood grass aqueous solution, stirs and heat that to be completely dissolved it standby
With;
B. laruyl alcohol sodium sulfovinate is added in the sweet wormwood grass extraction aqueous solution of occupancy 40 ± 4%, is stirred, it is standby;
C. silica, saccharin, Sodium Benzoate, sodium pyrophosphate are well mixed, it is standby;
D. qinghaosu and Artesunate are dissolved in the mixing liquid of sorbierite, propane diols, polyethylene glycol, it is standby;
E. step b and step d gained is added in vacuum Manufacturing medicine extract machine, opens vacuum and stirring, after stirring, add step c
Middle gained extracts the aqueous solution with remaining sweet wormwood grass, and essence and step a gained are added after stirring, and after stirring, recovers
To normal pressure, lotion is obtained.
The preferred embodiments of the present invention are the foregoing is only, is not intended to limit the invention, for the skill of this area
For art personnel, there can be various modifications and variations in the spirit and principles in the present invention, these equivalent modifications or replacement etc.,
It is all contained within protection scope of the present invention.
Claims (10)
1. a kind of sweet wormwood toothpaste, it is characterised in that its raw materials by weight is calculated as:Rubbing agent 18~25%, adhesive
0.3~0.6%, NMF 54~64%, foaming agent 2~7%, sweetener 0.05~0.2%, preservative 0.1~0.4%, pyrophosphoric acid
Sodium 0.3~0.6%, essence 1~2%, qinghaosu or Artesunate 0.1~0.3%, balance of sweet wormwood grass extract the aqueous solution.
2. a kind of sweet wormwood toothpaste according to claim 1, it is characterised in that:Described NMF is sorbierite, poly- second two
The mixing of alcohol -1450, propane diols.
3. a kind of sweet wormwood toothpaste according to claim 1 and 2, it is characterised in that its raw materials by weight is calculated as two
Silica 18~25%, cellulose gum 0.3~0.6%, laruyl alcohol sodium sulfovinate 2~4%, sorbierite 50~55%, polyethylene glycol-
1450 2~4%, propane diols 2~5%, Sodium Benzoate 0.1~0.4%, saccharin 0.05~0.2%, sodium pyrophosphate 0.3~0.6% is fragrant
Essence 1~2%, qinghaosu or Artesunate 0.1~0.3%, its balance of sweet wormwood grass extract the aqueous solution.
4. a kind of sweet wormwood toothpaste according to claim 1, it is characterised in that:It is to use 85 that described sweet wormwood grass extracts the aqueous solution
~90 DEG C of deionized water carries out 10~20min of immersion to fresh sweet wormwood, filtering, obtains, fresh green grass or young crops described by weight
Wormwood artemisia:Deionized water=1:35~45.
5. a kind of sweet wormwood toothpaste according to claim 4, it is characterised in that:Fresh sweet wormwood:Deionized water=1:40.
6. the preparation method of a kind of sweet wormwood toothpaste as described in claim 1-5 is any, it is characterised in that comprise the following steps:
A. adhesive is added in the sweet wormwood grass extraction aqueous solution of occupancy 30 ± 3%, stirring and heating is completely dissolved it, standby
With;
B. foaming agent is added in the sweet wormwood grass extraction aqueous solution of occupancy 40 ± 4%, is stirred, it is standby;
C. rubbing agent, sweetener, preservative, sodium pyrophosphate are well mixed, it is standby;
D. qinghaosu or Artesunate are dissolved in NMF, it is standby;
E. step b and step d gained is added in vacuum Manufacturing medicine extract machine, opens vacuum and stirring, after stirring, add step c
Middle gained extracts the aqueous solution with remaining sweet wormwood grass, and essence and step a gained are added after stirring, and after stirring, recovers
To normal pressure, lotion is obtained.
7. the preparation method of a kind of sweet wormwood toothpaste according to claim 6, it is characterised in that:In the step e step b with
When step d gained is mixed, vacuum is -0.8MPa, mixing speed is 60 ± 4r/min, and mixing time is 15~25min.
8. the preparation method of a kind of sweet wormwood toothpaste according to claim 6, it is characterised in that:Step is added in the step e
After rapid c gained extracts the aqueous solution with remaining sweet wormwood grass, vacuum is -0.95~-0.85MPa, and mixing time is 10~15min.
9. the preparation method of a kind of sweet wormwood toothpaste according to claim 6, it is characterised in that:Step is added in the step e
Rapid a institutes with essence after, vacuum is -0.85~-0.8MPa, and mixing time is 20~25min.
10. the preparation method of a kind of sweet wormwood toothpaste according to claim 6, it is characterised in that:Also include after the step e
It is stored in packing step.
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Cited By (6)
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CN109381381A (en) * | 2017-08-08 | 2019-02-26 | 贵州美人芋农业发展有限公司 | A kind of sweet wormwood powder tooth-caring toothpaste and preparation method thereof |
CN109498490A (en) * | 2018-12-16 | 2019-03-22 | 丹东欣时代生物医药科技有限公司 | One kind dentifrice composition containing Artesunate and preparation method thereof |
CN109609267A (en) * | 2019-01-10 | 2019-04-12 | 德利宝(广州)香料有限公司 | A kind of preparation method of Artemisinin essence and dentifrice composition containing the essence |
CN110613801A (en) * | 2018-06-20 | 2019-12-27 | 株式会社 Lg 生活健康 | Composition for preventing or treating oral diseases comprising Artemisia annua and bamboo salt |
CN113143803A (en) * | 2021-04-22 | 2021-07-23 | 蒋鑫 | Artemisia oil toothpaste and preparation method thereof |
CN116350564A (en) * | 2023-05-16 | 2023-06-30 | 浙江爱尚日用品有限公司 | Gum protecting and bleeding stopping toothpaste and preparation method thereof |
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Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
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CN109381381A (en) * | 2017-08-08 | 2019-02-26 | 贵州美人芋农业发展有限公司 | A kind of sweet wormwood powder tooth-caring toothpaste and preparation method thereof |
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CN110613801B (en) * | 2018-06-20 | 2023-03-28 | 株式会社 Lg 生活健康 | Oral composition for preventing or improving oral diseases and use thereof |
CN109498490A (en) * | 2018-12-16 | 2019-03-22 | 丹东欣时代生物医药科技有限公司 | One kind dentifrice composition containing Artesunate and preparation method thereof |
CN109609267A (en) * | 2019-01-10 | 2019-04-12 | 德利宝(广州)香料有限公司 | A kind of preparation method of Artemisinin essence and dentifrice composition containing the essence |
CN113143803A (en) * | 2021-04-22 | 2021-07-23 | 蒋鑫 | Artemisia oil toothpaste and preparation method thereof |
CN116350564A (en) * | 2023-05-16 | 2023-06-30 | 浙江爱尚日用品有限公司 | Gum protecting and bleeding stopping toothpaste and preparation method thereof |
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Application publication date: 20170623 |