CN106841586B - A kind of integration chromatography detection device - Google Patents

A kind of integration chromatography detection device Download PDF

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Publication number
CN106841586B
CN106841586B CN201710054468.2A CN201710054468A CN106841586B CN 106841586 B CN106841586 B CN 106841586B CN 201710054468 A CN201710054468 A CN 201710054468A CN 106841586 B CN106841586 B CN 106841586B
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Prior art keywords
component
sample
auxiliary liquid
detection device
side wall
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CN106841586A (en
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陆易鑫
白佳委
汪大明
陈梁
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Intec Products Inc Xiamen
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Intec Products Inc Xiamen
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses component, a lower component and side components in a kind of integration chromatography detection device, including one, and upper component, lower component and side component are removably connected by buckle structure.The present invention realizes the processing of sample in a unified device, the control of sample-adding, and since operation is a possibility that carrying out in the system of a relative closure, also reduce sample contamination to a certain extent, the simplicity of operation decreases the hidden danger of manual operation error.

Description

A kind of integration chromatography detection device
Technical field
The invention belongs to medicinal detection device technical fields, and in particular to a kind of integration chromatography detection device.
Background technique
Chromatography detection device is due to needing other many instruments to be used cooperatively at present, and there is certain not convenient on Property.Currently, the processing to sample generally carries out in independent container, transfer is carried out to sample with pipettor again later and is added Sample.Operation mode so a possibility that there is sample contaminations, and it is related to more vessel, for certain sensibility Sample nor optimal processing scheme.
Summary of the invention
It is an object of the invention to overcome prior art defect, a kind of integration chromatography detection device is provided.
Technical scheme is as follows:
A kind of integration chromatography detection device, comprising:
Component on one, including a upper body, the upper body is interior to be equipped with a blood taking needle, and the blood taking needle stretches out the one of upper body Side wall is to acquire blood sample;
One lower component, including a lower body, at least one layer of analysis strip and at least one auxiliary liquid sample-adding pipe, at least one layer analysis Strip is set in lower body, and auxiliary liquid sample-adding pipe runs through the side wall of lower body, and upper body is stretched out in one end of auxiliary liquid sample-adding pipe Side wall, the end tip shape, the other end is located in lower body and the sample-adding portion of the corresponding chromatography strip;
With side component, upper part has an auxiliary liquid accommodating chamber, and its underpart has at least water conservancy diversion through two sidewalls Pipe, the auxiliary liquid accommodating chamber have a transparent soft side wall;
Upper component, lower component are removably connected with side component, and upper component is located at the top of lower component, and side component is located at upper The overall thickness of the side of component and lower component, the upper component and lower component is identical as the thickness of side component;Assist liquid sample-adding pipe One end respective side component auxiliary liquid accommodating chamber soft side wall;One end of the diversion pipe of side component is to receive blood sample This, the other end corresponds to the sample-adding portion of the chromatography strip of lower component;The relatively upper component of side component and lower component have a first position With a second position, when being located at first position, soft side wall is not contacted with one end of auxiliary liquid sample-adding pipe, when positioned at second When setting, one end of auxiliary liquid sample-adding pipe penetrates soft side wall.
In a preferred embodiment of the invention, the upper component, lower component and side component can by buckle structure Disassembly is connected.
In a preferred embodiment of the invention, the upper body of the upper component has a box body for accommodating desiccant The upper cover of the box body is set with a lid.
In a preferred embodiment of the invention, the lower body of the lower component has the upper housing being clamped up and down With a lower case, which is equipped with the card slot of at least one adaptation chromatography strip.
It is further preferred that the upper housing has observation window, to the corresponding portion as the result is shown for showing chromatography strip.
In a preferred embodiment of the invention, the other end of the auxiliary liquid sample-adding pipe is located at adding for chromatography strip On sample portion.
Beneficial effects of the present invention:
1, the present invention realizes the acquisition of sample in a unified device and is loaded and chromatographs detection, and due to Operation is a possibility that carrying out in the system of a relative closure, also reduce sample contamination to a certain extent, operation Simplicity decreases the hidden danger of manual operation error.
2, structure of the invention is simple, low in cost.
Detailed description of the invention
Fig. 1 is schematic perspective view of the invention.
Fig. 2 is perspective exploded view of the invention.
Specific embodiment
Technical solution of the present invention is further explained and described below by way of specific embodiment combination attached drawing.
As depicted in figs. 1 and 2, component 1, a lower component 2 and side group in a kind of integration chromatography detection device, including one Part 3, upper component 1, lower component 2 and side component 3 are removably connected by buckle structure.
Upper component 1, including a upper body 10, the upper body 10 is interior to be equipped with a blood taking needle 11, and the blood taking needle 11 stretches out The one side wall of ontology 10 is to acquire blood sample, in addition, box body 101 and a lid that upper body 10 also accommodates desiccant with one If the upper cover 102 of the box body 101;
Lower component 2, including a lower body 20, at least one layer of analysis strip 21 and at least one auxiliary liquid are loaded pipe 22, this is at least One chromatography strip 21 is set in lower body 20, which is loaded the side wall that pipe 22 runs through lower body 20, and auxiliary liquid is loaded pipe 22 One end stretch out the side wall of upper body 10, which is tip shape, and the other end is located in lower body 20 and the correspondence chromatography strip 21 Sample-adding portion;Lower body 20 has the upper housing 201 being clamped up and down and a lower case 202, which is equipped at least One card slot 2020, chromatography strip 21 are set in the card slot 2020, and upper housing 201 has observation window 2010, to corresponding display layer Analyse the portion as the result is shown of strip 21;
Side component 3, upper part have an auxiliary liquid accommodating chamber 31, and its underpart has at least diversion pipe through two sidewalls 32, which has the soft side wall 310 of a transparent masking foil material;
Upper component 1, lower component 2 and side component 3 are removably connected, and upper component 1 is located at the top of lower component 2, side component 3 Positioned at the side of upper component 1 and lower component 2, the overall thickness of upper component 1 and lower component 2 is identical as the thickness of side component 3;Assist liquid It is loaded the soft side wall 310 of the auxiliary liquid accommodating chamber 31 of one end respective side component 3 of pipe 22, the other end is located at chromatography strip 21 On sample-adding portion;One end of the diversion pipe 32 of side component 3 corresponds to the chromatography examination of lower component 2 to receive blood sample, the other end The sample-adding portion of item 21;The relatively upper component 1 of side component 3 and lower component 2 have a first position and a second position, when positioned at first When position, soft side wall 310 is not contacted with one end of auxiliary liquid sample-adding pipe 22, when in the second position, auxiliary liquid sample-adding pipe 22 one end penetrates soft side wall 310.
Specifically used method of the invention is as follows:
(1) before carrying out detection operation, upper component 1, lower component 2 and side component 3 engage, at the same make side component 3 relatively under Component 2 and upper component 1 are in first position, i.e. one end with pointed structures of auxiliary liquid sample-adding pipe 22 does not contact soft side wall 310;
(2) finger of subject is poked with blood taking needle 11, is contacted after finger takes enough blood volumes with diversion pipe 32, by blood Liquid water conservancy diversion loading extremely chromatographs the sample-adding portion of strip 21;
(3) then push side component 3 to upper component 1 and lower component 2, make at the opposite lower component 2 of side component 3 and upper component 1 In the second position, assists one end with sharp mechanism of liquid sample-adding pipe 22 to poke soft side wall 310, liquid accommodating chamber 31 will be assisted Interior auxiliary liquid is loaded the sample-adding portion that pipe 22 is guided to chromatography strip 21 by auxiliary liquid, can pass through observation after a period of time 2010 testing result of window.
The foregoing is only a preferred embodiment of the present invention, the range that the present invention that therefore, it cannot be limited according to is implemented, i.e., Equivalent changes and modifications made in accordance with the scope of the invention and the contents of the specification should still be within the scope of the present invention.

Claims (6)

1. a kind of integration chromatography detection device, it is characterised in that: include:
Component on one, including a upper body, the upper body is interior to be equipped with a blood taking needle, and the blood taking needle stretches out the one side wall of upper body To acquire blood sample;
One lower component, including a lower body, at least one layer of analysis strip and at least one auxiliary liquid sample-adding pipe, at least one layer analyse strip In lower body, auxiliary liquid sample-adding pipe runs through the side wall of lower body, and the side of lower body is stretched out in one end of auxiliary liquid sample-adding pipe Wall, the end tip shape, the other end is located in lower body and the sample-adding portion of the corresponding chromatography strip;
With side component, upper part has an auxiliary liquid accommodating chamber, and its underpart has at least diversion pipe through two sidewalls, should Assist liquid accommodating chamber that there is a transparent soft side wall;
Upper component, lower component are removably connected with side component, and upper component is located at the top of lower component, and side component is located at upper component With the side of lower component, the overall thickness of the upper component and lower component is identical as the thickness of side component;Assist the one of liquid sample-adding pipe Hold the soft side wall of the auxiliary liquid accommodating chamber of respective side component;One end of the diversion pipe of side component is to receive blood sample, separately One end corresponds to the sample-adding portion of the chromatography strip of lower component;The relatively upper component of side component and lower component have a first position and one the Two positions, when being located at first position, soft side wall is not contacted with one end of auxiliary liquid sample-adding pipe, when in the second position, One end of auxiliary liquid sample-adding pipe penetrates soft side wall.
2. a kind of integration chromatography detection device as described in claim 1, it is characterised in that: the upper component, lower component and Side component is removably connected by buckle structure.
3. a kind of integration chromatography detection device as described in claim 1, it is characterised in that: the upper body of the upper component has The box body and one for having a receiving desiccant cover the upper cover for setting the box body.
4. a kind of integration chromatography detection device as described in claim 1, it is characterised in that: the lower body of the lower component has There are the upper housing being clamped up and down and a lower case, which is equipped with the card slot of at least one adaptation chromatography strip.
5. a kind of integration chromatography detection device as claimed in claim 4, it is characterised in that: the upper housing has observation Window, to the corresponding portion as the result is shown for showing chromatography strip.
6. a kind of integration chromatography detection device as described in claim 1, it is characterised in that: the auxiliary liquid is loaded the another of pipe One end is located on the sample-adding portion of chromatography strip.
CN201710054468.2A 2017-01-22 2017-01-22 A kind of integration chromatography detection device Active CN106841586B (en)

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CN109917142A (en) * 2019-04-01 2019-06-21 北京怡成生物电子技术股份有限公司 A kind of blood sample multi objective translocation cartridge
CN112881696B (en) * 2021-01-13 2021-11-02 北京中检葆泰生物技术有限公司 Detection method and system for stably detecting aflatoxin content

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EP1692501B1 (en) * 2003-11-14 2016-01-06 Alere Switzerland GmbH Rapid sample analysis and storage devices and methods of use
CN101876661A (en) * 2009-05-08 2010-11-03 艾博生物医药(杭州)有限公司 Device for analyzing analyte in liquid sample
PL2676606T3 (en) * 2012-06-20 2017-10-31 Fabpulous B V Quick test device and method
CN103278625A (en) * 2013-04-28 2013-09-04 上海快灵生物科技有限公司 Closed type chromatography test paper detection device and application method of closed type chromatography test paper detection device
CN103760330B (en) * 2013-12-31 2016-03-30 杭州迪图科技有限公司 A kind ofly to collect and the device of analyte in test fluid sample
CN105784443B (en) * 2016-03-16 2018-12-07 杭州安旭科技有限公司 A kind of sample testing apparatus and sample collection detection device and method

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Address after: 361000 Xinguang Road 332, Haicang Xinyang Industrial Zone, Xiamen City, Fujian Province

Patentee after: Yingke Xinchuang (Xiamen) Science and Technology Co., Ltd.

Address before: 361000 Xinguang Road 332, Haicang Xinyang Industrial Zone, Xiamen City, Fujian Province

Patentee before: Yingke Xinchuang (Xiamen) Science & Technology Co., Ltd.