CN106841586A - A kind of integration chromatography detection means - Google Patents

A kind of integration chromatography detection means Download PDF

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Publication number
CN106841586A
CN106841586A CN201710054468.2A CN201710054468A CN106841586A CN 106841586 A CN106841586 A CN 106841586A CN 201710054468 A CN201710054468 A CN 201710054468A CN 106841586 A CN106841586 A CN 106841586A
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China
Prior art keywords
component
sample
auxiliary liquid
detection means
integration
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CN201710054468.2A
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CN106841586B (en
Inventor
陆易鑫
白佳委
汪大明
陈梁
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Intec Products Inc Xiamen
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Intec Products Inc Xiamen
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses component, once component and side component in a kind of integration chromatography detection means, including one, upper component, lower component are removably connected with side component by buckle structure.The present invention realizes the treatment of sample in a unified device, the control of sample-adding, and because operation is carried out in a system for relative closure, the possibility of sample contamination is also reduced to a certain extent, the simplicity of operation decreases the hidden danger of artificial operating error.

Description

A kind of integration chromatography detection means
Technical field
The invention belongs to medicinal detection device technical field, and in particular to a kind of integration chromatography detection means.
Background technology
Chromatography detection means is certain not convenient using above existing due to needing other many apparatuses to use cooperatively at present Property.At present, the treatment to sample is typically carried out in independent container, and transfer is carried out to sample with pipettor again afterwards adds Sample.Operator scheme so there is a possibility that sample contamination, and be related to more vessel, for some sensitiveness Sample, the also processing scheme of non-optimal.
The content of the invention
It is an object of the invention to overcome prior art defect, there is provided a kind of integration chromatography detection means.
Technical scheme is as follows:
A kind of integration chromatography detection means, including:
Body on component, including one on one, is provided with a blood taking needle in body on this, and the blood taking needle stretches out the one of body Side wall is to gather blood sample;
Component, including body, at least one of which analysis strip and at least one auxiliary liquid sample-adding pipe, at least one of which analysis once once In lower body, through the side wall of lower body, body is stretched out in one end of auxiliary liquid sample-adding pipe to auxiliary liquid sample-adding pipe to strip Side wall, the end tip shape, the other end is located in lower body and to that should chromatograph the sample-adding portion of strip;
With side component, with an auxiliary liquid accommodating chamber, its underpart has at least water conservancy diversion through two side on its top Pipe, the auxiliary liquid accommodating chamber has a transparent soft side wall;
Upper component, lower component are removably connected with side component, and upper component is located at the top of lower component, and side component is located at upper The gross thickness of the side of component and lower component, the upper component and lower component is identical with the thickness of side component;Auxiliary liquid sample-adding pipe One end respective side component auxiliary liquid accommodating chamber soft side wall;One end of the mozzle of side component is used to receive blood sample This, the sample-adding portion of the chromatography strip of the lower component of other end correspondence;Side component goes up component and lower component relatively has a first position With a second place, when positioned at first position, soft side wall is not contacted with one end of auxiliary liquid sample-adding pipe, when positioned at second When putting, one end of auxiliary liquid sample-adding pipe penetrates soft side wall.
In a preferred embodiment of the invention, the upper component, lower component and side component can by buckle structure That dismantles is connected.
In a preferred embodiment of the invention, the upper body of the upper component has a box body for accommodating drier With the upper lid that a lid sets the box body.
In a preferred embodiment of the invention, the lower body of the lower component has a upper shell of upper and lower clamping With a lower house, the lower house be provided with least one adaptation it is described chromatography strip draw-in groove.
It is further preferred that the upper shell has observation window, it is used to the result display part of correspondence display chromatography strip.
In a preferred embodiment of the invention, the other end of the auxiliary liquid sample-adding pipe is located at adding for chromatography strip On sample portion.
Beneficial effects of the present invention:
1st, the present invention realized in a unified device sample collection and, sample-adding and chromatography detection, and due to Operation is carried out in a system for relative closure, and the possibility of sample contamination is also reduced to a certain extent, operation Simplicity, decreases the hidden danger of artificial operating error.
2nd, simple structure of the invention, with low cost.
Brief description of the drawings
Fig. 1 is dimensional structure diagram of the invention.
Fig. 2 is perspective exploded view of the invention.
Specific embodiment
Technical scheme is further detailed and described below by way of specific embodiment combination accompanying drawing.
As depicted in figs. 1 and 2, component 1, once component 2 and side group in a kind of integration chromatography detection means, including one Part 3, upper component 1, lower component 2 are removably connected with side component 3 by buckle structure.
Upper component 1, including body 10 on, a blood taking needle 11 is provided with this in body 10, and the blood taking needle 11 stretches out The side wall of body 10 is to gather blood sample, additionally, also there is upper body 10 box body 101 and for accommodating drier to cover If the upper lid 102 of the box body 101;
Lower component 2, including body 20, at least one of which analysis strip 21 and at least one auxiliary liquid sample-adding pipe 22 once, this is at least In lower body 20, auxiliary liquid sample-adding pipe 22 aids in liquid sample-adding pipe 22 to one chromatography strip 21 through the side wall of lower body 20 One end stretch out the side wall of body 10, the end is tip shape, and the other end is located in lower body 20 and to that should chromatograph strip 21 Sample-adding portion;Lower body 20 has a upper shell 201 and a lower house 202 of upper and lower clamping, and the lower house 202 is provided with least One draw-in groove 2020, in the draw-in groove 2020, upper shell 201 has observation window 2010 to chromatography strip 21, is used to correspondence display layer Analyse the result display part of strip 21;
Side component 3, its top has an auxiliary liquid accommodating chamber 31, and its underpart has at least mozzle through two side 32, the auxiliary liquid accommodating chamber 31 has the soft side wall 310 of a transparent masking foil material;
Upper component 1, lower component 2 are removably connected with side component 3, and upper component 1 is located at the top of lower component 2, side component 3 Positioned at upper component 1 and the side of lower component 2, the gross thickness of upper component 1 and lower component 2 is identical with the thickness of side component 3;Auxiliary liquid The soft side wall 310 of the auxiliary liquid accommodating chamber 31 of one end respective side component 3 of pipe 22 is loaded, the other end is located at chromatography strip 21 On sample-adding portion;One end of the mozzle 32 of side component 3 is used to receive blood sample, the chromatography examination of the lower component 2 of other end correspondence The sample-adding portion of bar 21;Side component 3 goes up component 1 and lower component 2 relatively has a first position and a second place, when positioned at first During position, soft side wall 310 is not contacted with one end of auxiliary liquid sample-adding pipe 22, when in the second position, auxiliary liquid sample-adding pipe 22 one end penetrates soft side wall 310.
Specifically used method of the invention is as follows:
(1) before detection operation is carried out, upper component 1, lower component 2 and side component 3 engage, while under making side component 3 relatively Component 2 and upper component 1 are in first position, that is, aid in one end with pointed structures of liquid sample-adding pipe 22 not contact soft side wall 310;
(2) finger of subject is poked with blood taking needle 11, is contacted with mozzle 32 after finger takes enough blood volumes, by blood Liquid water conservancy diversion loading extremely chromatographs the sample-adding portion of strip 21;
(3) then push side component 3 to upper component 1 and lower component 2, side component 3 is played relatively at component 2 and upper component 1 In the second place, soft side wall 310 is poked in one end with sharp mechanism of auxiliary liquid sample-adding pipe 22, by auxiliary liquid accommodating chamber 31 Interior auxiliary liquid is loaded the sample-adding portion that pipe 22 is guided to chromatography strip 21 by aiding in liquid, by observation by after a period of time The testing result of window 2010.
The above, only presently preferred embodiments of the present invention, therefore can not according to this limit the scope of present invention implementation, i.e., The equivalence changes made according to the scope of the claims of the present invention and description and modification, all should still belong in the range of the present invention covers.

Claims (6)

1. a kind of integration chromatographs detection means, it is characterised in that:Including:
Body on component, including one on one, is provided with a blood taking needle in body on this, and the blood taking needle stretches out the side wall of body To gather blood sample;
Component, including body, at least one of which analysis strip and at least one auxiliary liquid sample-adding pipe, at least one of which analysis strip once once In lower body, through the side wall of lower body, the side of body is stretched out in one end of auxiliary liquid sample-adding pipe to auxiliary liquid sample-adding pipe Wall, the end tip shape, sample-adding portion of the other end in lower body and to strip should be chromatographed;
With side component, its top has at least mozzle through two side, is somebody's turn to do with an auxiliary liquid accommodating chamber, its underpart Auxiliary liquid accommodating chamber has a transparent soft side wall;
Upper component, lower component are removably connected with side component, and upper component is located at the top of lower component, and side component is located at upper component With the side of lower component, the gross thickness of the upper component and lower component is identical with the thickness of side component;The one of auxiliary liquid sample-adding pipe The soft side wall of the auxiliary liquid accommodating chamber of end respective side component;One end of the mozzle of side component is used to receive blood sample, separately The sample-adding portion of the chromatography strip of the lower component of one end correspondence;Side component goes up component and lower component relatively has a first position and one the Two positions, when positioned at first position, soft side wall is not contacted with one end of auxiliary liquid sample-adding pipe, when in the second position, One end of auxiliary liquid sample-adding pipe penetrates soft side wall.
2. a kind of integration as claimed in claim 1 chromatographs detection means, it is characterised in that:The upper component, lower component and Side component is removably connected by buckle structure.
3. a kind of integration as claimed in claim 1 chromatographs detection means, it is characterised in that:The upper body tool of the upper component The box body and a lid for having a receiving drier set the upper lid of the box body.
4. a kind of integration as claimed in claim 1 chromatographs detection means, it is characterised in that:The lower body tool of the lower component There are a upper shell and a lower house of upper and lower clamping, the lower house is provided with the draw-in groove of at least one adaptation chromatography strip.
5. a kind of integration as claimed in claim 4 chromatographs detection means, it is characterised in that:The upper shell has observation Window, is used to the result display part of correspondence display chromatography strip.
6. a kind of integration as claimed in claim 1 chromatographs detection means, it is characterised in that:The auxiliary liquid is loaded the another of pipe One end is located on the sample-adding portion of chromatography strip.
CN201710054468.2A 2017-01-22 2017-01-22 A kind of integration chromatography detection device Active CN106841586B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109917142A (en) * 2019-04-01 2019-06-21 北京怡成生物电子技术股份有限公司 A kind of blood sample multi objective translocation cartridge
CN112881696A (en) * 2021-01-13 2021-06-01 北京中检葆泰生物技术有限公司 Detection method and system for stably detecting aflatoxin content

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1882835A (en) * 2003-11-14 2006-12-20 香港澳维有限公司 Fluid sample analysis device with sealable storage reservoir
CN101876661A (en) * 2009-05-08 2010-11-03 艾博生物医药(杭州)有限公司 Device for analyzing analyte in liquid sample
WO2013191552A1 (en) * 2012-06-20 2013-12-27 Fabpulous B.V. Quick test device and method
CN103529201A (en) * 2013-04-28 2014-01-22 上海快灵生物科技有限公司 Closed chromatographic test paper detection device as well as using method thereof
CN103760330A (en) * 2013-12-31 2014-04-30 杭州迪图科技有限公司 Device for collecting and detecting analytes in fluid sample
CN105784443A (en) * 2016-03-16 2016-07-20 杭州安旭科技有限公司 Sample detection device, and sample collection and detection device and method

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1882835A (en) * 2003-11-14 2006-12-20 香港澳维有限公司 Fluid sample analysis device with sealable storage reservoir
CN101876661A (en) * 2009-05-08 2010-11-03 艾博生物医药(杭州)有限公司 Device for analyzing analyte in liquid sample
WO2013191552A1 (en) * 2012-06-20 2013-12-27 Fabpulous B.V. Quick test device and method
CN103529201A (en) * 2013-04-28 2014-01-22 上海快灵生物科技有限公司 Closed chromatographic test paper detection device as well as using method thereof
CN103760330A (en) * 2013-12-31 2014-04-30 杭州迪图科技有限公司 Device for collecting and detecting analytes in fluid sample
CN105784443A (en) * 2016-03-16 2016-07-20 杭州安旭科技有限公司 Sample detection device, and sample collection and detection device and method

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109917142A (en) * 2019-04-01 2019-06-21 北京怡成生物电子技术股份有限公司 A kind of blood sample multi objective translocation cartridge
CN112881696A (en) * 2021-01-13 2021-06-01 北京中检葆泰生物技术有限公司 Detection method and system for stably detecting aflatoxin content
CN112881696B (en) * 2021-01-13 2021-11-02 北京中检葆泰生物技术有限公司 Detection method and system for stably detecting aflatoxin content

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Address after: 361000 Xinguang Road 332, Haicang Xinyang Industrial Zone, Xiamen City, Fujian Province

Patentee after: Yingke Xinchuang (Xiamen) Science and Technology Co., Ltd.

Address before: 361000 Xinguang Road 332, Haicang Xinyang Industrial Zone, Xiamen City, Fujian Province

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