CN106596928A - Vacuum blood sampling diagnosis test tube - Google Patents
Vacuum blood sampling diagnosis test tube Download PDFInfo
- Publication number
- CN106596928A CN106596928A CN201611095985.6A CN201611095985A CN106596928A CN 106596928 A CN106596928 A CN 106596928A CN 201611095985 A CN201611095985 A CN 201611095985A CN 106596928 A CN106596928 A CN 106596928A
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- test tube
- vacuum blood
- blood collection
- defecator
- diagnosis test
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150251—Collection chamber divided into at least two compartments, e.g. for division of samples
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
- A61B5/154—Devices using pre-evacuated means
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Manufacturing & Machinery (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention relates to a vacuum blood sampling diagnosis test tube. The vacuum blood sampling diagnosis test tube comprises a tube body, a seal cover, a liquid collection chamber, a filtering apparatus, a detection test paper, a bottom cap and a fixed plate, the liquid collection chamber is arranged in the tube body, a detection test paper is arranged between the tube body and the fixed plate, the seal cover is the vacuum test tube seal cover analogous with a common negative pressure hemostix, and is composed of a plastic cover and a rubber plug, the two ends of the tube body are opened, a hollow part is the liquid collection chamber, the tube body, the seal cover, the bottom cap, and the fixed plate are mutually and fixedly connected to form a sealing chamber, the liquid collection chamber is in a tapering structure, the diameter of the filtering apparatus and the diameter of the fixed position required by the liquid collection chamber are closely cooperated, so that the filtering apparatus is firmly fixed in the liquid collection chamber, the liquid collection chamber is divided into two cavities, after the filtering apparatus is fixed, the height value between the upper surface to the lower surface of the seal cover is larger than the syringe needle length of the common blood taking needles.
Description
Technical field
The present invention relates to medical apparatus and instruments, more particularly to a kind of vacuum blood collection diagnosis test tube, sample for vacuum blood collection and right
Blood sample carries out quick diagnosis examination.
Background technology
From the prior art, the vacuum blood collection diagnosis test tube for using is disclosed in the market does not filter erythrocyte work(
Can, erythrocyte participates in running plate, causes the detection background of Test paper very high, so as to the excessive detection of product is uncertain, affects
The degree of accuracy of diagnosis.Meanwhile, do not have vacuum directly to adopt the+vacuum blood collection diagnosis test tube product of reactor on market, individually yet
Disclosed patent, vacuum chamber are little, and the blood of collection is very limited, it is difficult to accomplish the multiple indexs of one-time detection；Also due to knot
Structure is complicated, and steel edge, carriage etc. are also equipped with test tube, and processing technology is extremely complex, and precision is high, and cost is significantly gone up
Rise, be not suitable for popularizing use on a large scale.
The content of the invention
The present invention be directed to problem above, there is provided a kind of vacuum blood collection diagnosis test tube, including body, closure, liquid collecting cavity,
Defecator, Test paper, bottom, fixed plate, the liquid collecting cavity are arranged on tubular body, and Test paper is arranged on body and consolidates
Between fixed board, described closure is the vacuum test tube closure similar with the negative pressure hemostix commonly used, typically by vinyl cover and
Rubber stopper is constituted, and described body two ends are open, and hollow space is liquid collecting cavity, body, closure, bottom, fixed plate
The composition that is mutually permanently connected seal cavity, the liquid collecting cavity be upper coarse and lower fine structure, the diameter and liquid collecting cavity of the defecator
The diameter close fit of required fixed position, it is sufficient to be securely fixed in liquid collecting intracavity, and liquid collecting cavity is divided into into upper and lower two
Cavity, after the defecator is fixed, the height value of its upper surface to closure lower surface is at least than the syringe needle of conventional blood taking needle
Length value is bigger.Further, the liquid collecting cavity can be made up of two sections cylindrical cavity, and the diameter at Upper cylindrical cavity is big
In the diameter of lower cylindrical cavity, Upper cylindrical cavity forms a hollow round table, the circle with the junction surface of lower cylindrical cavity
Defecator is fixed with platform shape structure, the defecator is preferably cylinder, the internal diameter phase of its diameter and Upper cylindrical pipe
Match somebody with somebody.
Described defecator is completely separated with serum, blood plasma for erythrocyte in the blood sample by collection, wherein blood
Liquid flow to lower cylindrical pipe after the defecator, and carries out chromatography reaction by bottom stream to Test paper.Test paper
Physically there is the relation of conducting with liquid collecting cavity so that the blood after filtration can be reacted with Test paper.
Preferably, described defecator is made up of the macromolecular material with certain degree of hardness, and the such as filtration is filled
Put and be made up of PVA materials.Further, also include in defecator for erythrocyte is completely separated with blood plasma, serum
Biological or chemical component, such as RBC antibody and/or surfactant etc..
Body can be the empty capsid being made by transparent materials such as PET, transparent ABS, PS, and the thickness of body can be
0.5-2.5mm；Preferably between 0.8-2mm, more preferably 1-1.5mm, the size of body, shape can be according to diagnosis need
Determining, body can be arranged to cylinder, cuboid or multi-faceted column to reagent paper quantity to be adopted, detect as needed
Index quantity, is fixed with some Test papers between fixed plate and body, the neutral gear except leaving necessary observation amount of blood collected
Outward, it is also possible to fixed plate and Test paper are respectively arranged with different faces.Further, for the ease of control collection blood sample
Quantity, can be being provided with the scale of display number on body.
Preferably, the bottom design of the vacuum blood collection diagnosis test tube is tapered, is easy to serum to gather to the surrounding of bottom.
Further, on bottom arranging guiding gutter to the position for being provided with Test paper from the peak of bottom taper, then can enter
One step, guiding gutter can be arranged to the corrugated vertical with liquid flow direction.
Preferably, described Test paper can be fluorescent quantitation reagent paper, gold colloidal or latex test strip.
Preferably, described closure is made up of a hollow tubular protuberance and a test tube cap, the hollow pipe
External screw thread can be provided with shape protuberance outer circumference surface, be provided with the test tube cap inner peripheral surface and hollow tubular protuberance
The female thread that upper external screw thread matches, everyday process can be by test tube cap be tightened on hollow tubular protuberance, preferably
Ensure the physical stability of test tube interior, prevent closure from damaging.Above-mentioned hollow tubular protuberance and test tube cap can also pass through
Other modes are fixed together.
Further, test tube cap can also be arranged to the hollow form of two opening, by directly piercing through with blood taking needle
Rubber seal plug use cooperatively, closure is protected.So not only contribute to prevent closure from damaging, additionally it is possible to more
Blood sample is gathered easily.
The fixed plate of the vacuum blood collection diagnosis test tube be used for fix reagent paper, the fixed plate can take snap connection, glue
The methods such as glutinous agent connection are fixedly connected with body, according to diagnosis or the needs for detecting in fixed plate, are fixed with respective amount
Reagent paper, or the reagent paper of respective amount can also be fixed on body, described diaphragm seal, body, liquid collecting cavity, fixed plate
Vacuum state is formed between bottom, the bottom of reagent paper just contacts and do not occur deviation with bottom, kept between different reagent paper
Separate state.The vacuum blood collection diagnosis test tube keeps sterile vacuum state under storage, transport etc. not use state, and which is internal true
Reciprocal of duty cycle scope is 0.1-0.9 atmospheric pressure.
Further, since serum is during examination paper chromatgraphy, need to start 5 to the 15min of reaction in serum and reagent paper
Interior reaction is finished, and the result for obtaining is only accurately, otherwise the response time it is long or it is too short be all easily caused diagnostic result mistake
Very, cause mistaken diagnosis.Start the response time to accurately grasp reagent paper and serum, obtain more accurate diagnostic data, can be with
The time started of serum and reagent paper is obtained accurately using the principle of reflection of monochromater.Further, as serum is reacted with reagent paper
Overlong time, can cause that diagnostic result error is excessive to cause mistaken diagnosis, therefore, a reaction is installed on the upper position of fixed plate
Termination instruction lamp, the corresponding reagent paper of display lamp color when serum is chromatographed to the position change, and are incident upon the position
Light is partly absorbed, and the light for reflecting is changed by color during the reaction termination instruction lamp, is shown
Diagnostic result may be inaccurate result.
A kind of method of quick blood sampling diagnosis, mainly uses vacuum blood collection diagnosis test tube recited above, and its step is such as
Under：1. need to gather necessary quantity of blood according to detection project；2. the blood for being gathered is filtrated to get through defecator to be treated
Survey liquid；3. diagnostic result is read within 1min to the 15min time periods after the completion of collection blood.
Preferably, diagnostic result is being read in 5min to the 15min time periods after the completion of collection blood.
The invention has the beneficial effects as follows：
1st, erythrocyte is separated from blood, can in effectively anti-Hemostatic Oral Liquid erythrocyte and other impurities it is dry
Disturb, effectively improve the accuracy of Testing index.
2nd, liquid collecting cavity can be arranged to different size according to the needs of detection project and human body feature, flexibly can arrange
Different detection paper is to required index.
3rd, structure and simple and reliable process, with low cost, is easy to large-area popularization and application.
4th, by further improvement, some detection instruction equipments can be installed additional, is prevented because artificial origin causes detection
Insufficient or detection time-out and caused diagnostic result is inaccurate.
5th, by using described vacuum blood collection diagnosis test tube, diagnostic result is read in the stipulated time, can be greatly improved
Accuracy rate to blood samples of patients diagnosis.
Description of the drawings
In order to be illustrated more clearly that the present invention, embodiment will be described below needed for accompanying drawing to be used simply be situated between
Continue.It should be evident that drawings in the following description are only the description to embodiments of the invention, for ordinary skill
For personnel, without having to pay creative labor, can be carrying out simple deformation or title according to technical scheme
Change, or take customary means, it is also possible to realize goal of the invention.
Fig. 1：The axonometric chart of vacuum blood collection diagnosis test tube
Fig. 2：Omit the explosive view of the vacuum blood collection diagnosis test tube on body two sides
Fig. 3：The bottom of vacuum blood collection diagnosis test tube
Label declaration：1- bodys, 2- hollow tubular protuberances, 3- liquid collecting cavities, 4- defecators, 5- Test papers, 6 bottoms
Lid, 7- fixed plates, 8- test tube caps, 9- rubber seal plugs, 10- guiding gutters
Specific embodiment
With reference to embodiment, the present invention is described in further detail, following examples be explanation of the invention and
The invention is not limited in following examples.
Embodiment 1
As shown in Figure 1, Figure 2, Figure 3 shows, a kind of vacuum blood collection diagnosis test tube, by body 1, closure, liquid collecting cavity 3, filters dress
Put 4, Test paper 5, bottom 6, fixed plate 7 to constitute, liquid collecting cavity 3 is arranged on tubular body, and body is made up of transparent ABS material,
Test paper 5 is medical Test paper gold colloidal, is arranged between body 1 and fixed plate 7, and closure is by hollow tubular protuberance
2nd, test tube cap 8 and rubber seal plug 9 are constituted, and by the close fit between three, test tube can be made to keep more preferable stability.
Described 1 two ends of body are open, and hollow space is liquid collecting cavity 3, structure between body 1, closure, bottom 6, fixed plate 7
Into seal cavity, the liquid collecting cavity 3 be two sections cylindrical cavity composition, at body Upper cylindrical cavity with diameter greater than bottom
The diameter of cylindrical cavity, Upper cylindrical cavity form a hollow round table with the junction surface of lower cylindrical cavity, and the truncated cone-shaped is tied
Defecator 4 is fixed with structure, the defecator 4 is cylinder, and its diameter matched with the diameter of Upper cylindrical cavity, the mistake
Filter device is made up of PVA materials, also includes RBC antibody and surfactant, and bottom 6 has made taper, also sets on its surface
It is equipped with guiding gutter 10.
During use, blood taking needle one end is penetrated patient's vein by testing staff, and the other end penetrates vacuum blood collection diagnosis test tube and enters
Row blood sampling, the blood of collection pass through the defecator 4 of liquid collecting intracavity, and erythrocyte is stayed in Upper cylindrical cavity, and serum oozed
Lower cylindrical cavity is entered into after defecator, under the guide functions of the guiding gutter 10 on bottom 6, is collected at Test paper
It is poly-, and acted on by the chromatography with Test paper, the indices of patient are detected.Testing staff can be by reading inspection
Test paper obtains diagnostic result.Blood from after filtration is started the clock in examination paper chromatgraphy, the inspection obtained in 5-15min
Survey results contrast accurate.
Although the present invention is disclosed as above with embodiment, which is not limited to protection scope of the present invention, any ripe
The technical staff of the technology is known, in the variation made without departing from the spirit and scope of the invention and retouching, this all should be belonged to
The protection domain of invention.
Claims (10)
1. a kind of vacuum blood collection diagnosis test tube, including body, closure, liquid collecting cavity, defecator, Test paper, bottom, fixation
Plate, the liquid collecting cavity are arranged on tubular body, and Test paper is arranged between body and fixed plate, body, closure, bottom,
A seal cavity is constituted between fixed plate, it is characterised in that：The liquid collecting cavity is upper coarse and lower fine structure, and the defecator fixes
In liquid collecting intracavity, and liquid collecting cavity is divided into into upper and lower two cavitys, tubular body is in integrally negative pressure state, negative pressure value for-
0.01—0.09Mpa。
2. vacuum blood collection diagnosis test tube as claimed in claim 1, it is characterised in that：Described defecator is by macromolecular material
Make.
3. vacuum blood collection diagnosis test tube as claimed in claim 2, it is characterised in that：Described defecator is by PVA material systems
Into.
4. vacuum blood collection diagnosis test tube as claimed in claim 2, it is characterised in that：Also include in the defecator containing
RBC antibody and/or surfactant.
5. any one vacuum blood collection diagnosis test tube as described in Claims 1-4, it is characterised in that：The bottom is arranged to
Taper with guiding gutter.
6. any one vacuum blood collection diagnosis test tube as described in Claims 1-4, it is characterised in that：Described Test paper
For immune chromatography test paper.
7. vacuum blood collection diagnosis test tube according to claim 7, it is characterised in that：Described immuno-chromatographic test paper strip is glimmering
Signal, colloid gold label, latex labeled immunochromatographyassay assay test-strip.
8. any one vacuum blood collection diagnosis test tube as described in Claims 1-4, it is characterised in that：The thickness of the body
For 1mm to 1.5mm.
9. any one vacuum blood collection diagnosis test tube as described in Claims 1-4, it is characterised in that：The closure is by
Empty tubular projections, test tube cap and rubber seal plug composition.
10. a kind of method that quick blood sampling is diagnosed, it is characterised in that：Using the vacuum blood collection diagnosis examination as described in claim 1-4
Pipe carries out blood sampling diagnosis, and its step is：1. need to gather necessary quantity of blood according to detection project；2. the blood Jing for being gathered
Cross defecator and be filtrated to get testing liquid；3. diagnosis knot is read within 5min to the 15min time periods after the completion of collection blood
Really.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611095985.6A CN106596928B (en) | 2016-12-02 | 2016-12-02 | Vacuum blood collection diagnosis test tube |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611095985.6A CN106596928B (en) | 2016-12-02 | 2016-12-02 | Vacuum blood collection diagnosis test tube |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106596928A true CN106596928A (en) | 2017-04-26 |
| CN106596928B CN106596928B (en) | 2018-10-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611095985.6A Active CN106596928B (en) | 2016-12-02 | 2016-12-02 | Vacuum blood collection diagnosis test tube |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107669281A (en) * | 2017-11-02 | 2018-02-09 | 犹银俊 | Animal blood serum gathers test tube and serum separator |
| CN110575185A (en) * | 2019-09-23 | 2019-12-17 | 江苏科华医疗器械科技有限公司 | Dry-wet separation type blood collection tube |
| CN110595838A (en) * | 2019-09-06 | 2019-12-20 | 安徽福贸生物科技有限公司 | Vacuum sampling sample liquid detection device |
| CN112472084A (en) * | 2020-11-30 | 2021-03-12 | 重庆医科大学附属第一医院 | Sterile blood sampling facility based on organ transplantation early detection |
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| US6506167B1 (en) * | 1997-12-24 | 2003-01-14 | I-Design Co., Ltd. | Blood-collecting tubes |
| CN1754506A (en) * | 2004-09-28 | 2006-04-05 | 贾宇东 | Test tube for vacuum blood sampling and quick diagnosis |
| CN101051046A (en) * | 2006-04-03 | 2007-10-10 | 贾宇东 | Vacuum diagnostic test tube |
| CN200973714Y (en) * | 2006-11-17 | 2007-11-14 | 高凤玲 | Blood collecting and separating integrated type blood collecting device |
| CN101261230A (en) * | 2007-10-08 | 2008-09-10 | 马义才 | Portable sample rapid joint inspection device |
| WO2013082301A1 (en) * | 2011-11-29 | 2013-06-06 | Teleflex Medical, Inc. | Device with integrated allergy testing |
| CN206657020U (en) * | 2016-12-02 | 2017-11-21 | 杭州康永生物技术有限公司 | A kind of vacuum blood collection diagnosis test tube |
-
2016
- 2016-12-02 CN CN201611095985.6A patent/CN106596928B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506167B1 (en) * | 1997-12-24 | 2003-01-14 | I-Design Co., Ltd. | Blood-collecting tubes |
| CN1754506A (en) * | 2004-09-28 | 2006-04-05 | 贾宇东 | Test tube for vacuum blood sampling and quick diagnosis |
| CN101051046A (en) * | 2006-04-03 | 2007-10-10 | 贾宇东 | Vacuum diagnostic test tube |
| CN200973714Y (en) * | 2006-11-17 | 2007-11-14 | 高凤玲 | Blood collecting and separating integrated type blood collecting device |
| CN101261230A (en) * | 2007-10-08 | 2008-09-10 | 马义才 | Portable sample rapid joint inspection device |
| WO2013082301A1 (en) * | 2011-11-29 | 2013-06-06 | Teleflex Medical, Inc. | Device with integrated allergy testing |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107669281A (en) * | 2017-11-02 | 2018-02-09 | 犹银俊 | Animal blood serum gathers test tube and serum separator |
| CN110595838A (en) * | 2019-09-06 | 2019-12-20 | 安徽福贸生物科技有限公司 | Vacuum sampling sample liquid detection device |
| CN110575185A (en) * | 2019-09-23 | 2019-12-17 | 江苏科华医疗器械科技有限公司 | Dry-wet separation type blood collection tube |
| CN110575185B (en) * | 2019-09-23 | 2022-02-18 | 江苏科华医疗器械科技有限公司 | Dry-wet separation type blood collection tube |
| CN112472084A (en) * | 2020-11-30 | 2021-03-12 | 重庆医科大学附属第一医院 | Sterile blood sampling facility based on organ transplantation early detection |
| CN112472084B (en) * | 2020-11-30 | 2022-07-19 | 重庆医科大学附属第一医院 | Sterile blood sampling facility based on organ transplantation early detection |
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| Publication number | Publication date |
|---|---|
| CN106596928B (en) | 2018-10-19 |
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Effective date of registration: 20190430 Address after: 310018 69 No. 12 Street, Hangzhou Economic and Technological Development Zone, Zhejiang Province Patentee after: Kangyong Biotechnology Co., Ltd. Address before: 310018 No. 17, 14th Street, Hangzhou Economic and Technological Development Zone, Zhejiang Province Patentee before: PROMETHEUS INC. |