CN101051046A - Vacuum diagnostic test tube - Google Patents

Vacuum diagnostic test tube Download PDF

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Publication number
CN101051046A
CN101051046A CN 200610011601 CN200610011601A CN101051046A CN 101051046 A CN101051046 A CN 101051046A CN 200610011601 CN200610011601 CN 200610011601 CN 200610011601 A CN200610011601 A CN 200610011601A CN 101051046 A CN101051046 A CN 101051046A
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China
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vacuum
test tube
receiving tray
gold
labelled
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CN 200610011601
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Chinese (zh)
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贾宇东
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Individual
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Individual
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Abstract

A diagnosis test tube of vacuum consists of gold labeling diagnosis test paper, test paper frame, quantitative liquid collection tube, liquid absorption fiber dryer, vacuum test tube and sealing film of vacuum test tube for finalizing vacuum blood-taking in once operation under completely closed condition.

Description

Vacuum diagnostic test tube
Technical field
The present invention relates to medicine equipment and diagnose test paper, be particularly related to a kind of vacuum diagnostic test tube, be used for the accurate quantitative sampling of vacuum blood collection and blood sample is carried out multinomial quick diagnosis examination simultaneously, and sealing in vitro finish above-mentioned two kinds of functions, realize three functions such as offal treatment function of safely and fast totally-enclosed blood sampling function, totally-enclosed field diagnostic function accurately and timely and safety and environmental protection.
Technical background
At present, vacuum blood collection operation and test paper fast detecting operation onrelevant, vacuum blood collection is to be used with detecting instrument with the air-tight manner blood sample collection again, is the blood collection procedure of closed mode; Diagnose test paper is to use and exposes blood sample (as referring to blood, ear blood or blood collection needle etc.) and unlimited mode of operation, the blood sample danger that cross-infection arranged or disseminate in spite of illness.
Prior art comprises that the patent No. of my invention is that the ZL01119996.2 patent of invention " poly-to stupid dioctyl phthalate glycol ester plastic test tube vacuum precision preserving method " and the patent No. are that ZL01219689.4 utility model patent " metallic seal film vacuum test tube and special use thereof are got and filled in device " is perfect to vacuum blood drawing technique, can not be connected use with diagnose test paper; The number of patent application that also comprises invention in person is 200410080305.4 patent of invention " test tube for vacuum blood sampling and quick diagnosis ", be to realize 2 process butt joints by 2 times before and after test tube operations, process is loaded down with trivial details, may leak blood sample and can not satisfy the technical requirement of gold test strip on precision micro-quantitative supply blood sample.
Current diagnosis test paper technology is cooperated with liking the biological medicine company (Beijing) of moral biotech development (China) company limited and Blue-Cross company limited as: CDC, " test paper; refers to blood " developed in success, and fast qualitative detects SARS virus antibody; Human immunodeficiency virus HIV (1+2 type) antibody diagnosing reagent kit (the golden mark method) accurate word-S20030001 of traditional Chinese medicines gets blood with blood taking needle at the finger tip place, drips blood 80 microlitres, observations at the application of sample place of HIV test card; The patent No. is that the ZL00226544.3 " whole blood hepatitis B antigen, antibody protein detection chip " and the patent No. are that the use of the blood sample of ZL00226807.8 " virus hepatitis antidiastole biochip " all is that open type exposes operation, using as point blood, ear blood or blood collection needle mode provides blood sample for the detection test paper, this usefulness blood mode is to expose blood sampling to be in the open exposure state with the discarded object that exposes after operating and detecting, and might cause artificial misoperation to cause the infectiousness hematologic disease to disseminate and cross infection in the test paper use.
In addition, the collection of blood sample and handover diagnose test paper link are loaded down with trivial details, the job costs height, and the time cycle is long, and it is many to pollute discarded object, and the efforts at environmental protection amount is big, has strengthened the probability of operation control cost and dangerous emergency.
Summary of the invention
Purpose of the present invention just provides vacuum diagnostic test tube, it is 1 that vacuum blood collection process and diagnose test paper testing process are closed 2, operate by the disposable blood of getting the same with general vacuum blood collection test tube, continuously sealing standard ground is enclosed in blood collection procedure and diagnostic procedure and samely in vitro finishes, thereby the little quantitative sample that promptly offers a plurality of gold test strip precisions after a sealing is in vitro with quantitative negative pressure of vacuum technology blood sample collection automatically continuously simultaneously carries out multinomial quick diagnosis to this blood sample, and keeps discarded blood sample and test paper to be enclosed in all the time in vitro up to final processing.Thereby solving blood sample exposes and gathers and the unsafe problems of easy cross-infection such as open type operation diagnose test paper or infection; it is safe and reliable and pollute the safety and environmental protection of offal treatment to reach overall process; simplify the operation simultaneously and reduce environmental baseline and operative technique requirement; unified blood sample standard; make testing result more accurate; reduce cost, realize closure, standardization, serialization, safe and the environmental protectionization of overall process operation.
Technical scheme of the present invention is:
Comprise gold-labelled diagnosis test paper (4), form receiving tray (2), quantitative collector tube (3), liquid sucting fiber (5), drying agent (13), vacuum test tube (1) and vacuum test tube diaphragm seal (7), successively insert form receiving tray (2) in the vacuum test tube (1), gold-labelled diagnosis test paper (4), liquid sucting fiber (5) and quantitative collector tube (3), extracting the opening of quantitative vacuum condition under using vacuum test tube diaphragm seal (7) sealed vacuum test tube (1) thereafter, wherein form receiving tray (2) inner chamber is placed drying agent (13), form receiving tray (2) fixed outside gold-labelled diagnosis test paper (4), form receiving tray (2) top lateral surface shrinks to the axle center and forms groove, form the quantitative storage liquid gap (10) of quantitative volume with the following inwall of quantitative collector tube (3), the imbibition section that liquid sucting fiber (5) and gold-labelled diagnosis test paper (4) are quantitatively arranged in the storage liquid gap (10), each quantitatively the liquid sucting fiber (5) in storage liquid gap (10) compile in outside, form receiving tray top and connect and corresponding with quantitative collector tube (3) internal orifice, quantitatively collector tube (3) collar extension has quantitative collector tube diaphragm seal (6) sealing and in abutting connection with the inner face of vacuum test tube diaphragm seal (7).
Described vacuum test tube (1) is the transparent plastic material injection mo(u)lding.
Described vacuum test tube diaphragm seal (7) has the isolated function of air, and thickness is at 0.1mm-1.0mm.
Described vacuum test tube diaphragm seal (7) can and vacuum test tube (30) port merge sealing.
Described rubber blanket (2) is circular, medical rank, thickness 2.0mm-5.0mm.
Described gold-labelled diagnosis test paper (4) is the multiple diagnostic function that can have various disease or index.
Described form receiving tray (2) inner chamber is placed with drying agent, and outside surface is fixed with one or more gold-labelled diagnosis test paper (4).
The cecum exchange set liquid sucting fiber (5) of described form receiving tray (2) test tube mouth direction.
Between the cecum of described form receiving tray (2) test tube mouth direction and the vacuum test tube diaphragm seal (7) is quantitative collector tube (3).
Be coated with anticoagulation reagent powder in the described quantitative collector tube (3).
The present invention utilizes vacuum blood drawing technique to draw a certain amount of blood sample with the quantitative negative pressure of setting in the vacuum test tube, blood sample is drawn into respectively in the quantitative gap at imbibition section place of each gold-labelled diagnosis test paper (4) by liquid sucting fiber (5) continuously again and provides the sample size that designs for gold-labelled diagnosis test paper (4), therefore can in vitro continue follow-up process up to display result same, the discarded object of finishing diagnosis the most at last maintains environmental protection treatment under the closed state, all processes seals continuously, safe and reliable, simple to operate, be beneficial to environmental requirement, cost of products and use and management cost reduce, and prevent the cross-infection of blood-borne diseases.
Description of drawings
Fig. 1 is a basic structure synoptic diagram of the present invention.
Embodiment
Referring to Fig. 1, this embodiment comprises gold-labelled diagnosis test paper (4), form receiving tray (2), quantitative collector tube (3), liquid sucting fiber (5), drying agent (13), vacuum test tube (1) and vacuum test tube diaphragm seal (7), successively insert form receiving tray (2) in the vacuum test tube (1), gold-labelled diagnosis test paper (4), liquid sucting fiber (5) and quantitative collector tube (3), extracting the opening of quantitative vacuum condition under using vacuum test tube diaphragm seal (7) sealed vacuum test tube (1) thereafter, wherein form receiving tray (2) inner chamber is placed drying agent (13), form receiving tray (2) fixed outside gold-labelled diagnosis test paper (4), form receiving tray (2) top lateral surface shrinks to the axle center and forms groove, form the quantitative storage liquid gap (10) of quantitative volume with the following inwall of quantitative collector tube (3), the imbibition section that liquid sucting fiber (5) and gold-labelled diagnosis test paper (4) are quantitatively arranged in the storage liquid gap (10), each quantitatively the liquid sucting fiber (5) in storage liquid gap (10) compile in outside, form receiving tray top and connect and corresponding with quantitative collector tube (3) internal orifice, quantitatively collector tube (3) collar extension has quantitative collector tube diaphragm seal (6) sealing and in abutting connection with the inner face of vacuum test tube diaphragm seal (7).
Embodiment below in conjunction with Fig. 1 elaborates to 26S Proteasome Structure and Function of the present invention.
Place gold-labelled diagnosis test paper (4) in the vacuum test tube (1), and be in the negative pressure of vacuum preservation state before use all the time; Gold-labelled diagnosis test paper (4) display surface is outside, the back side is corresponding with form receiving tray (2), the imbibition end is positioned at vacuum test tube (1) opening direction; Form receiving tray (2) one end openings, the other end is a blind pipe, and its blind pipe end is positioned at vacuum test tube (1) opening direction, and form receiving tray (2) inner chamber is desiccant chamber (13), wherein places particle shape drying agent; Form receiving tray (2) cecum lateral surface shrinks to the axle center and forms groove, and the imbibition section and the liquid sucting fiber (5) of gold-labelled diagnosis test paper (4) arranged in the groove; Liquid sucting fiber (5) end face outside form receiving tray (2) cecum in each groove of form receiving tray (2) cecum lateral surface merges into the one-piece construction of one 3 dimension form, the corresponding quantitatively internal orifice of collector tube (3) of point; Quantitatively collector tube (3) collar extension is sealed by quantitative collector tube diaphragm seal (6), the point of the corresponding liquid sucting fiber of internal orifice (5) end face outside form receiving tray (2) cecum; Accompany sept between the imbibition section of gold-labelled diagnosis test paper (4) and vacuum test tube (1) inwall, be collector tube bottom (14), thickness is 0.01 to 5 millimeter, between the display segment of imbibition section back and vacuum test tube (1) inwall 0.01 to 5 millimeter test paper gap (11) is arranged; Quantitatively in the collector tube (3) quantitative anticoagulation reagent powder is being arranged; Vacuum test tube (1) is the plastic material manufacturing, has transparent nature, and the vacuum test tube diaphragm seal (7) of its opening part is that plastics and metal composite form.
Gold-labelled diagnosis test paper (4) back side is fixed in the form receiving tray (2), test paper spacing (16) is arrived in the lower end, the test tube flange (15) and vacuum test tube diaphragm seal (7) welded seal of vacuum test tube (1) mouthful end, the bonding again caulking gum in the centre of its outside surface (8) is used for sealing needle tip
Drawing quantitative blood sample by quantitative negative-pressure vacuum, after this blood sample enters quantitative collector tube (3) earlier with anticoagulation reagent powder or directly enter, saturated absorption by liquid sucting fiber (5) and being distributed in a plurality of quantitative storage liquid gaps (10) again, imbibition section so that the sample size of regulation is given gold-labelled diagnosis test paper (4) altogether forms an amount of sample diffusion effect and diagnostic result.
The diagnosis of vacuum blood collection and test paper is two processes separately implementing in the prior art.
For example: the patent No. of my invention is that the ZL01119996.2 patent of invention " poly-to stupid dioctyl phthalate glycol ester plastic test tube vacuum precision preserving method " and the patent No. are that ZL01219689.4 utility model patent " metallic seal film vacuum test tube and special use thereof are got and filled in device " is perfect to vacuum blood drawing technique, can not be connected use with diagnose test paper;
The number of patent application that also comprises invention in person in addition is 200410080305.4 patent of invention " test tube for vacuum blood sampling and quick diagnosis ", though be in vitro to implement at one, but realize 2 process butt joints by 2 times before and after test tube operations, process is loaded down with trivial details, sample is in communication with the outside, and may leak that blood sample pollutes and can not satisfy the technical requirement of gold test strip on precision micro-quantitative supply blood sample.
At present other diagnose test paper technology as: CDC is cooperated with liking the biological medicine company (Beijing) of moral biotech development (China) company limited and Blue-Cross company limited, " test paper; refers to blood " developed in success, and fast qualitative detects SARS virus antibody; Human immunodeficiency virus HIV (1+2 type) antibody diagnosing reagent kit (the golden mark method) accurate word-S20030001 of traditional Chinese medicines gets blood with blood taking needle at the finger tip place, drips blood 80 microlitres, observations at the application of sample place of HIV test card; The patent No. is a ZL00226544.3 " whole blood hepatitis B antigen, the antibody protein detection chip " and the patent No. be that the use of the blood sample of ZL00226807.8 " virus hepatitis antidiastole biochip " all is that open type exposes operation, still do not relate to how mutual airtight being used to blood sample, it only is the function of independently having finished diagnosis, use as finger blood, ear blood or blood collection needle mode provide blood sample for the detection test paper, this usefulness blood mode is to expose blood sampling to be in the open exposure state with the discarded object that exposes after operating and detecting, and might cause artificial misoperation to cause the infectiousness hematologic disease to disseminate and cross infection in the test paper use.The vacuum blood collection notion just began at nearest 8 years to popularize clinical in addition, and a lot of zones are not contact also, deep along with the understanding of blood-borne disease, and requiring totally enclosed blood sampling and diagnosis is clinical basic improvement.
" vacuum diagnostic test tube " of the present invention is in vitro only just can finish " blood sampling " and " diagnosis " 2 functions continuously automatically by single job in same complete closed.
Reach the standardization of overall process operation; serialization; safe; environmental protectionization and closure; simplified too much operation technique and the step of test paper operation simultaneously; form the operation standard of a unified blood sample for detection paper; a line that reduces misoperation ratio and motor-driven open air of adaptation or the bad area of condition uses; simplified staff's operating process; the high safety high speed degree of high-level efficiency is low-cost high motor-driven; make more standard and accurately of testing result; to solve operating process separation and the exposure sample of blood, drawn that prior art exists; complicated operating process; pollution or infection probability are big; to operating personnel's technical requirement height; immobilized operational facilities conditional request height brings cross-infection or infection, reduces the high use cost and the handling cost of complex process; improve the security of overall process; with the safety and environmental protection level that improves the waste disposal that the equipment that hematologic disease pollutes is arranged, operate the shortening time simultaneously, will take a blood sample and detection is in vitro finished same.

Claims (10)

1, a kind of vacuum diagnostic test tube, it is characterized in that: comprise gold-labelled diagnosis test paper (4), form receiving tray (2), quantitative collector tube (3), liquid sucting fiber (5), drying agent (13), vacuum test tube (1) and vacuum test tube diaphragm seal (7), form receiving tray (2), gold-labelled diagnosis test paper (4), liquid sucting fiber (5) and quantitative collector tube (3) are placed in the vacuum test tube (1), form receiving tray (2) inner chamber is desiccant chamber (12), wherein place drying agent (13), gold-labelled diagnosis test paper (4) pastes and is placed on form receiving tray (2) outside, the imbibition section of liquid sucting fiber (5) and gold-labelled diagnosis test paper (4) overlaps and covers, a plurality of liquid sucting fibers (5) are connected to each other at the end face of form receiving tray (2), and collar extension merged sealing with vacuum test tube diaphragm seal (7) after vacuum test tube (1) was taken out negative pressure;
2, vacuum diagnostic test tube according to claim 1 is characterized in that: the vacuum test tube (1) that is placed with gold-labelled diagnosis test paper (4) is in quantitative negative pressure of vacuum preservation state before use;
3, vacuum diagnostic test tube according to claim 1 is characterized in that: gold-labelled diagnosis test paper (4) display surface outwards, the back side and form receiving tray (2) applying, the imbibition end of gold-labelled diagnosis test paper (4) is positioned at the blood sampling direction of vacuum test tube (1);
4, vacuum diagnostic test tube according to claim 1 is characterized in that: or/and column, particle diameter is 0.01 millimeter to 10 millimeters to the drying agent (13) that the desiccant chamber (12) of form receiving tray (2) inner chamber is placed for graininess, and length is 1 millimeter to 100 millimeters;
5, vacuum diagnostic test tube according to claim 1, it is characterized in that: the partial sidewall of form receiving tray (2) one ends is to the recessed formation groove in axle center, and groove quantity is 1-20, and gold-labelled diagnosis test paper (4) the imbibition section and the liquid sucting fiber (5) of concave part is to overlap to cover directly to contact;
6, vacuum diagnostic test tube according to claim 1 is characterized in that: a plurality of liquid sucting fibers (5) converge the one-piece construction that forms 3 dimension forms at the end face of form receiving tray (2), are radiation when open and flat, and meet is in the face of the internal orifice of quantitative collector tube (3);
7, vacuum diagnostic test tube according to claim 1 is characterized in that: quantitatively collector tube (3) collar extension is by quantitative collector tube diaphragm seal (6) sealing and in abutting connection with the inner face of vacuum test tube diaphragm seal (7);
8, vacuum diagnostic test tube according to claim 1, it is characterized in that: accompany sept between the imbibition section of gold-labelled diagnosis test paper (4) and vacuum test tube (1) inwall, thickness is 0.01 to 5 millimeter, between the display segment of imbibition section back and vacuum test tube (1) inwall 0.01 to 5 millimeter test paper gap (11) is arranged;
9, vacuum diagnostic test tube according to claim 1 is characterized in that: the groove ends of form receiving tray (2) is blind pipe and the blood sampling direction that is positioned at vacuum test tube (1);
10, vacuum diagnostic test tube according to claim 1 is characterized in that: in quantitative collector tube (3) and quantitative anticoagulation reagent powder arranged on the liquid sucting fiber (5).
CN 200610011601 2006-04-03 2006-04-03 Vacuum diagnostic test tube Pending CN101051046A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200610011601 CN101051046A (en) 2006-04-03 2006-04-03 Vacuum diagnostic test tube

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Application Number Priority Date Filing Date Title
CN 200610011601 CN101051046A (en) 2006-04-03 2006-04-03 Vacuum diagnostic test tube

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CN101051046A true CN101051046A (en) 2007-10-10

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105326511A (en) * 2015-12-09 2016-02-17 国家纳米科学中心 Vacuum blood sampling device for immunity detection
CN106596928A (en) * 2016-12-02 2017-04-26 杭州康永生物技术有限公司 Vacuum blood sampling diagnosis test tube

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105326511A (en) * 2015-12-09 2016-02-17 国家纳米科学中心 Vacuum blood sampling device for immunity detection
CN105326511B (en) * 2015-12-09 2018-10-12 国家纳米科学中心 A kind of vacuum blood sampler for immune detection
CN106596928A (en) * 2016-12-02 2017-04-26 杭州康永生物技术有限公司 Vacuum blood sampling diagnosis test tube

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