CN106824890A - Method, device, equipment and system that Magneto separate is cleaned - Google Patents
Method, device, equipment and system that Magneto separate is cleaned Download PDFInfo
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- CN106824890A CN106824890A CN201710233164.2A CN201710233164A CN106824890A CN 106824890 A CN106824890 A CN 106824890A CN 201710233164 A CN201710233164 A CN 201710233164A CN 106824890 A CN106824890 A CN 106824890A
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- fluid
- cleaning
- injection needle
- storage configuration
- magneto separate
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/08—Cleaning involving contact with liquid the liquid having chemical or dissolving effect
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B13/00—Accessories or details of general applicability for machines or apparatus for cleaning
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B08—CLEANING
- B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
- B08B3/00—Cleaning by methods involving the use or presence of liquid or steam
- B08B3/04—Cleaning involving contact with liquid
- B08B3/10—Cleaning involving contact with liquid with additional treatment of the liquid or of the object being cleaned, e.g. by heat, by electricity or by vibration
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Method, device, equipment and system the invention discloses a kind of cleaning of Magneto separate, the method for Magneto separate cleaning include step：Cleaning fluid is imported into fluid injection pipeline and injection needle；The liquid discharged from injection needle is drained into storage configuration, the liquid in storage configuration is siphoned away using aspirating needle；When cleaning fluid is full of fluid injection pipeline and injection needle, Magneto separate cleaning is carried out to the magnetic bead in reaction cup.The method of Magneto separate cleaning disclosed by the invention, by to importing cleaning fluid in fluid injection pipeline and injection needle, discharged with the fluid that will be remained in fluid injection pipeline and injection needle, after cleaning fluid is full of fluid injection pipeline and injection needle, realize the fluid emptying that will be remained in fluid injection pipeline and injection needle, then Magneto separate cleaning is carried out to the magnetic bead in reaction cup again, so, the fluid influence for avoiding residual in fluid injection pipeline and injection needle enters the reservoir quantity of reaction cup, it is easy to ensure reservoir quantity, so as to improve cleaning performance.
Description
Technical field
The present invention relates to vitro diagnostic techniques field, method, device more specifically to a kind of cleaning of Magneto separate,
Equipment and system.
Background technology
In in-vitro diagnosis field, the measured object in detection sample is collected using magnetic bead more than chemiluminescence immunoassay technology
Matter, then carries out Magneto separate, purifies measured matter., it is necessary to injecting cleaning fluid in reaction cup during Magneto separate, by mixing
Impurity and distracter on stirring fully removal magnetic bead, in magnetic field the complete magnetic bead of adsorption reaction and by uncombined material with useless
Liquid is taken away together, realizes Magneto separate.
At present, cleaning fluid is injected to reaction cup using injection needle fluid injection, reservoir quantity directly affects cleaning performance.Usual fluid injection
Amount is controlled by controlling the injection rate of injection pump, but, it is easier to remain fluid in injection needle and fluid injection pipeline（Gas and
Liquid）, the fluid of residual can cause the reservoir quantity for entering reaction cup that deviation occurs, cause cleaning performance poor.
Therefore, how reservoir quantity is ensured, to improve cleaning performance, being that current those skilled in the art are urgently to be resolved hurrily asks
Topic.
The content of the invention
It is an object of the invention to provide a kind of method of Magneto separate cleaning, it is ensured that reservoir quantity, to improve cleaning performance.This hair
Bright another object is to provide a kind of device of Magneto separate cleaning, a kind of equipment of Magneto separate cleaning and a kind of cleaning of Magneto separate
System.
To achieve these goals, the present invention provides following technical scheme：
A kind of method of Magneto separate cleaning, including step：
Cleaning fluid is imported into fluid injection pipeline and injection needle；
The liquid discharged from the injection needle is drained into storage configuration, the liquid in the storage configuration is siphoned away using aspirating needle
Body；
When the cleaning fluid is full of the fluid injection pipeline and the injection needle, Magneto separate is carried out to the magnetic bead in reaction cup clear
Wash.
Preferably, determine that process of the cleaning fluid full of the fluid injection pipeline and the injection needle includes step：
When the import volume of the cleaning fluid is more than the capacity sum of the fluid injection pipeline and the injection needle, the cleaning fluid fills
Full the fluid injection pipeline and the injection needle.
Preferably, the importing number of times that the cleaning fluid imports the fluid injection pipeline and the injection needle is at least twice.
Preferably, in the method for above-mentioned Magneto separate cleaning, also include before being cleaned to the magnetic bead in the reaction cup
Step：
Control transhipment part motion, when the displacement structure positioned at the transhipment part initial bit is reached picks and places station, will react
Cup is placed on the displacement structure that station is picked and placeed described in arrival.
Preferably, the method for above-mentioned Magneto separate cleaning also includes step：
When the displacement structure do not reach it is described pick and place station when, then alarm and/or shut down；
When the station that picks and places is without the reaction cup, then alarms and/or shut down.
Preferably, in the method for above-mentioned Magneto separate cleaning, the liquid discharged from the injection needle is drained into the storage knot
In structure, step is specifically included：The injection needle is moved into the top of the storage configuration so that the injection needle and the storage
Structure is relative；
Liquid in the storage configuration is siphoned away using aspirating needle, step is specifically included：The aspirating needle is moved into the storage
Structure is so that the aspirating needle draws the liquid in the storage configuration.
The method of the Magneto separate cleaning that the present invention is provided, by cleaning fluid is imported in fluid injection pipeline and injection needle, inciting somebody to action
The fluid discharge of residual in fluid injection pipeline and injection needle, from the liquid discharged from injection needle is drained into storage configuration, using suction
Liquid pin siphons away the liquid in storage configuration, it is to avoid from the Magneto separate cleaning of the liquid influence reaction cup of injection needle discharge；When clear
After washing lotion is full of fluid injection pipeline and injection needle, the fluid emptying that will be remained in fluid injection pipeline and injection needle is realized, it is then right again
Magnetic bead in reaction cup carries out Magneto separate cleaning, so, it is to avoid the fluid influence of residual enters in fluid injection pipeline and injection needle
The reservoir quantity of reaction cup, is easy to ensure reservoir quantity, so as to improve cleaning performance.
The method of the Magneto separate cleaning based on above-mentioned offer, present invention also offers a kind of device of Magneto separate cleaning, should
The device of Magneto separate cleaning includes：
First control unit, for controlling cleaning fluid to import fluid injection pipeline and injection needle；
Second control unit, for controlling the liquid from injection needle discharge to flow in storage configuration and being inhaled for control
Liquid pin siphons away the liquid in the storage configuration；
3rd control unit, when the cleaning fluid is full of the fluid injection pipeline and the injection needle, for controlling the cleaning
Liquid carries out Magneto separate cleaning to the magnetic bead in reaction cup.
Preferably, the device of above-mentioned Magneto separate cleaning also includes：
Determining unit, when the import volume of the cleaning fluid is more than the capacity sum of the fluid injection pipeline and the injection needle, uses
In it is determined that the cleaning fluid is full of the fluid injection pipeline and the injection needle.
Preferably, first control unit is specially：For controlling the cleaning fluid to import the fluid injection at least twice
Pipeline and the injection needle.
Preferably, the device of above-mentioned Magneto separate cleaning also includes：
4th control unit, for controlling transhipment part motion；
First detection unit, station is picked and placeed for detecting whether the displacement structure positioned at the transhipment part initial bit reaches；
5th control unit, it is anti-for controlling when the displacement structure positioned at the transhipment part initial bit is reached picks and places station
Cup is answered to move to described picking and placeing on the displacement structure of station；
Second detection unit, described picks and places whether station has the reaction cup for detecting；
Wherein, the 3rd control unit specifically for：After the cleaning fluid is full of the fluid injection pipeline and the injection needle,
And it is described when picking and placeing station and having the reaction cup, control carries out Magneto separate cleaning to the magnetic bead in reaction cup.
Preferably, the device of above-mentioned Magneto separate cleaning also includes：
First protection location, when the displacement structure of the transhipment part initial bit do not reach it is described pick and place station when, for performing
Actuation of an alarm and/or shutdown action；
Second protection location, when it is described pick and place station without the reaction cup when, for performing actuation of an alarm and/or shutdown action.
Preferably, second control unit specifically for：The injection needle is controlled to move to the top of the storage configuration
So that the injection needle is relative with the storage configuration, controls the aspirating needle to move to the storage configuration and control the suction
Liquid pin siphons away the liquid in the storage configuration.
The device of the Magneto separate cleaning based on above-mentioned offer, present invention also offers a kind of equipment of Magneto separate cleaning, should
The equipment of Magneto separate cleaning includes：
Memory, for storing application program and the application program running in produce data；
Processor, for performing the application program, realizes following functions：Control cleaning fluid imports fluid injection pipeline and injection needle,
The liquid from injection needle discharge is controlled to drain into storage configuration, control aspirating needle siphons away the liquid in the storage configuration,
When the cleaning fluid is full of the fluid injection pipeline and the injection needle, for controlling the cleaning fluid to the magnetic bead in reaction cup
Carry out Magneto separate cleaning.
The equipment of the Magneto separate cleaning based on above-mentioned offer, present invention also offers a kind of system of Magneto separate cleaning, should
The equipment that the system of Magneto separate cleaning includes the Magneto separate cleaning described in above-described embodiment.
Preferably, storage configuration is arranged on the transhipment part of the system of the Magneto separate cleaning, and the transhipment part is used
In the placement reaction cup.
Preferably, the storage configuration at least two, and the storage configuration and the transhipment part displacement structure
Alternate setting, the displacement structure is used to place the reaction cup.
Brief description of the drawings
Technical scheme in order to illustrate more clearly the embodiments of the present invention, below will be to institute in embodiment or description of the prior art
The accompanying drawing for needing to use is briefly described, it should be apparent that, drawings in the following description are only embodiments of the invention, right
For those of ordinary skill in the art, on the premise of not paying creative work, can also be obtained according to the accompanying drawing for providing
Other accompanying drawings.
Fig. 1 is the flow chart of the method for the Magneto separate cleaning that the embodiment of the present invention one is provided；
Fig. 2 is the flow chart of the method for the Magneto separate cleaning that the embodiment of the present invention two is provided；
Fig. 3 is the distribution schematic diagram of station in the method that the Magneto separate that the embodiment of the present invention one and embodiment two are provided is cleaned.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clearly and completely
Description, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based on this hair
Embodiment in bright, the every other implementation that those of ordinary skill in the art are obtained under the premise of creative work is not made
Example, belongs to the scope of protection of the invention.
In order to ensure reservoir quantity, cleaning performance is improved, as shown in figure 1, the Magneto separate cleaning that the embodiment of the present invention one is provided
Method include step：
S11：Cleaning fluid is imported into fluid injection pipeline and injection needle：
With the importing of cleaning fluid, the fluid discharge that will be remained in fluid injection pipeline and injection needle.For the mode that cleaning fluid is imported,
Can be selected according to actual needs, for example, starting the valve imported on pump or priming pipeline and importing pump etc., this hair
Bright embodiment is not limited the lead-in mode of cleaning fluid.
S12：The liquid discharged from injection needle is drained into storage configuration, the liquid in storage configuration is siphoned away using aspirating needle
Body：
Can be air and liquid from the fluid of injection needle discharge during cleaning fluid is imported, also can be only liquid, the liquid bag
Including the liquid of residual and the cleaning fluid for importing or the liquid in injection needle and fluid injection pipeline only includes the cleaning fluid for importing.For
Avoid being cleaned from the liquid influence Magneto separate of injection needle discharge, the liquid discharged from injection needle drained into storage configuration, adopt
The liquid in storage configuration is siphoned away with aspirating needle.
Specifically, the liquid discharged from injection needle is drained into storage configuration and storage configuration is siphoned away using aspirating needle
, there are various implementations in interior liquid, for example, injection needle is moved at storage configuration so that injection needle and storage configuration pair
Together, the liquid from injection needle discharge is flowed directly into storage configuration；Aspirating needle is moved into storage configuration, by the motion of aspirating needle
Liquid in storage configuration is siphoned away.Certainly, also may be selected to connect injection needle and storage configuration using mozzle and interests are led
Flow tube connects aspirating needle and storage configuration, or mobile storage configuration to realize above-mentioned functions, it is not limited to above-described embodiment.
In order to simplify structure, it is easy to implement, the liquid discharged from injection needle is drained into storage configuration, specifically includes step
Suddenly：Injection needle is moved into the top of storage configuration so that injection needle is relative with storage configuration.
In order to simplify structure, it is easy to implement, the liquid in storage configuration is siphoned away using aspirating needle, specifically includes step：Will
Aspirating needle moves to storage configuration so that aspirating needle draws the liquid in storage configuration.
In order to simplify structure, above-mentioned storage configuration is arranged on transhipment part, and the transhipment part drives reaction cup motion.
Above-mentioned storage configuration can be holding tank or filling pipe 15, or accommodate tank etc., and the embodiment of the present invention is not done to this
Limit.
S13：When cleaning fluid is full of fluid injection pipeline and injection needle, Magneto separate cleaning is carried out to the magnetic bead in reaction cup：
When cleaning fluid is full of fluid injection pipeline and injection needle, show the fluid of residual in fluid injection pipeline and injection needle（Air and liquid
Body）By emptying, it is to avoid the fluid influence reservoir quantity of residual in fluid injection pipeline and injection needle, then now can be to the magnetic in reaction cup
Pearl carries out Magneto separate cleaning.
Determine mode of the cleaning fluid full of fluid injection pipeline and injection needle, exist various.For example, can be by the importing of cleaning fluid
The capacity sum of amount and fluid injection pipeline and injection needle is compared and determines, or is carried out by the amount of liquid discharged from injection needle
It is determined that.
Determine for convenience, determine that process of the cleaning fluid full of fluid injection pipeline and injection needle includes step：
When the import volume of cleaning fluid is more than the capacity sum of fluid injection pipeline and injection needle, cleaning fluid is full of fluid injection pipeline and fluid injection
Pin.
For the ease of the fluid emptying that will be remained in fluid injection pipeline and injection needle, cleaning fluid is imported into fluid injection pipeline and fluid injection
The importing number of times of pin is at least twice.In actual application, importing number of times is more, and emptying effect is better.It is secondary for importing
Several concrete numerical values, is designed according to actual needs, for example, import number of times and be 15 times or import number of times for 14 times or import
Number of times is 16 inferior, and the embodiment of the present invention is not limited it.
Specifically, importing number of times and n >=2 of the n for cleaning fluid, a is the single import volume of cleaning fluid, the then importing of cleaning fluid
It is a*n to measure.
Certainly, also may be selected when the import volume of cleaning fluid is equal to the capacity sum of fluid injection pipeline and injection needle, it is determined that clearly
Washing lotion is full of fluid injection pipeline and injection needle, it is not limited to above-described embodiment.
The method of the Magneto separate cleaning that the embodiment of the present invention one is provided, Magneto separate is carried out by the magnetic bead in reaction cup
Before cleaning, allow the cleaning fluid of importing to be full of fluid injection pipeline and injection needle, then realize residual in fluid injection pipeline and injection needle
Fluid emptying, it is to avoid the fluid influence reservoir quantity of residual in fluid injection pipeline and injection needle, also allows for ensureing reservoir quantity, improves
Cleaning performance；Meanwhile, from the liquid discharged from injection needle is drained into storage configuration, siphoned away in storage configuration using aspirating needle
Liquid, it is to avoid from the Magneto separate cleaning of the liquid influence reaction cup of injection needle discharge.
Further, the method that inventive embodiments two provide a kind of cleaning of Magneto separate, as shown in Fig. 2 the Magneto separate is clear
The method washed includes step：
S21：Cleaning fluid is imported into fluid injection pipeline and injection needle；
S22：The liquid discharged from injection needle is drained into storage configuration, the liquid in storage configuration is siphoned away using aspirating needle；
S23：Control transhipment part motion, detection picks and places station positioned at whether the displacement structure of transhipment part initial bit reaches, if
It is, then into step S24；If it is not, then alarming and/or shutting down；
S24：Reaction cup is placed on into arrival to pick and place on the displacement structure of station, and detection picks and places whether station has reaction cup, if
It is, then into step S25, if it is not, then alarming and/or shutting down；
S25：When cleaning fluid is full of fluid injection pipeline and injection needle, Magneto separate cleaning is carried out to the magnetic bead in reaction cup.
In the method for above-mentioned Magneto separate cleaning, it is ensured that reaction cup is placed on and picks and places station and initial positioned at transhipment part 14
On the displacement structure of position, so as to ensure that the cleaning of magnetic bead in reaction cup, it is to avoid maloperation, reliability is improve.
Above-mentioned actuation of an alarm can be performed by alarm lamp, can also be performed by buzzer；Above-mentioned shutdown action, is held by power switch
OK, the power switch can be the total power switch of the system of whole Magneto separate cleaning, and the power switch also can be only control transhipment
The power switch of part motion.The embodiment of the present invention is not limited the specific implementation alarmed and shut down.
In the method for the Magneto separate cleaning that the embodiment of the present invention two is provided, step S21, step S22, step S23, step
The sequencing of S24 and step S25 can be changed according to actual needs, for example, first carrying out step S23, step S24, then be held
Row step S21, step S22, finally perform step S25；In addition, above-mentioned steps S21, step S22, step S23 can also enter simultaneously
OK, it is not limited to the order that above-described embodiment is limited.
In the method for the Magneto separate cleaning that the embodiment of the present invention two is provided, step can be also saved in step S23：If it is not, then
Perform the first protection act；Also step can be saved in step S24：If it is not, then performing the second protection act.
In the method for the Magneto separate cleaning that the embodiment of the present invention two is provided, the specific implementation of step S22 refer to this
The description of inventive embodiments one, here is omitted.
In the method for the Magneto separate cleaning that above-described embodiment one and above-described embodiment two are provided, the magnetic bead in reaction cup is entered
The specific steps of row Magneto separate cleaning, can be designed according to actual needs.Preferably, magnetic point is carried out to the magnetic bead in reaction cup
Include step from cleaning：
S01：To injecting cleaning fluid in reaction cup；
S02：Magnetic bead in adsorption reaction cup；
S03：Exhaust the waste liquid in reaction cup；
S04：Again to injecting cleaning fluid in reaction cup, and mix the liquid and magnetic bead of reaction cup；
S05：Again adsorption reaction cup in magnetic bead；
S06：The waste liquid in reaction cup is exhausted again.
In the method for above-mentioned Magneto separate cleaning, in step S01, cleaned to being injected in the reaction cup equipped with sample and reagent
Liquid, in injection process, realizes mixing, reduces mixing time, improves Magneto separate cleaning efficiency.
In the method for above-mentioned Magneto separate cleaning, realize and clean twice.In order to improve cleaning performance, can suitably increase clear
Wash number of times.Further, in the method for above-mentioned Magneto separate cleaning, step is also included after step S06：Return to step S04.This
Sample, realizes repeat step S04, step S05 and step S06, and number of repetition is more, and wash number is more, and cleaning performance is better.
It is understood that in the method for above-mentioned Magneto separate cleaning, to cleaning fluid is injected in reaction cup, specially using note
Liquid pin in reaction cup to injecting cleaning fluid；Magnetic bead in adsorption reaction cup, is specially inhaled using the magnetic part of tool such as magnet
Magnetic bead in reaction enclosure cup；The waste liquid in reaction cup is exhausted, the waste liquid in reaction cup is specially exhausted using aspirating needle；Mix anti-
The liquid and magnetic bead of cup are answered, the liquid and magnetic bead of reaction cup are specially mixed using evenly mixing device.
The exhaustion time of waste liquid, adsorption time and mixing time in injection length, reaction cup for cleaning fluid, can basis
It is actually needed and is designed, the embodiment of the present invention is not limited this.
In order to accelerate cleaning efficiency, above-mentioned steps are performed in different stations.Specifically, the magnetic bead in reaction cup is carried out
Magneto separate cleaning includes step：
S001：Reaction cup is moved into the second station 2 and Preset Time is stopped, to injecting cleaning fluid in reaction cup；
S002：Reaction cup is moved into 3rd station 3 and Preset Time is stopped, the magnetic bead in adsorption reaction cup；
S003：Reaction cup is moved into the 4th station 4 and Preset Time is stopped, the waste liquid in reaction cup is exhausted；
S004：Reaction cup is moved into the 5th station 5 and Preset Time is stopped, again to injecting cleaning fluid in reaction cup, and mixed
The liquid and magnetic bead of reaction cup；
S005：Reaction cup is moved into the 6th station 6 and Preset Time is stopped, again the magnetic bead in adsorption reaction cup；
S006：Reaction cup is moved into the 7th station 7 and Preset Time is stopped, the waste liquid in reaction cup is exhausted again.
Numerical value for Preset Time is designed according to actual needs.In order to ensure Magneto separate effect, when above-mentioned default
Between be 10-15s.Further, Preset Time is 12s.Certainly, it is other Preset Time also to may be selected, it is not limited to above-mentioned
Embodiment.
The method of above-mentioned Magneto separate cleaning, realizes imbibition and fluid injection and is performed by different stations, effectively shortens each
Residence time needed for station, so as to improve Magneto separate cleaning efficiency.
In order to improve Magneto separate effect, increase cleaning step that can be appropriate, specifically, the method for above-mentioned Magneto separate cleaning
In, step is also included after step S006：
Repeat step S004, step S005 and step S006, repeat the step of S004, repeat the step of S005 and repeat the step of
S006 is performed by different stations respectively.
For number of repetition, also selected according to actual needs.Specifically, number of repetition is at least twice, and every time
Repeated the above steps by different stations.
, it is necessary to 13 stations as a example by being repeated twice, as shown in Figure 3.In the method for above-mentioned Magneto separate cleaning, in step
Also include step after S006：
S007：Reaction cup is moved into the 8th station 8 and Preset Time is stopped, again to injecting cleaning fluid in reaction cup, and mixed
The liquid and magnetic bead of reaction cup；
S008：Reaction cup is moved into the 9th station 9 and Preset Time is stopped, again the magnetic bead in adsorption reaction cup；
S009：Reaction cup is moved into the tenth station 10 and Preset Time is stopped, the waste liquid in reaction cup is exhausted again；
S0010：Reaction cup is moved into the 11st station 11 and Preset Time is stopped, again to injecting cleaning fluid in reaction cup, and
Mix the liquid and magnetic bead of reaction cup；
S0011：Reaction cup is moved into twelve-station 12 and Preset Time is stopped, again the magnetic bead in adsorption reaction cup；
S0012：Reaction cup is moved into the 13rd station 13 and Preset Time is stopped, the waste liquid in reaction cup is exhausted again.
In order to improve adsorption effect, adsorption time, above-mentioned steps S001, step S003, step S006, step can be increased
Also include the magnetic bead in step adsorption reaction cup in S009, step S0012.It should be noted that now, in adsorption reaction cup
The time of magnetic bead is Preset Time.
Further, in above-mentioned steps S001, the preceding N in Preset Time1In second, to injecting cleaning fluid in reaction cup,
So, adsorption effect is improve, the probability of magnetic bead loss is reduced.Preferably, N1=3.Certainly, N also may be selected1For other are counted
Value, such as N1=2, the embodiment of the present invention is not limited this.
Further, in above-mentioned steps S003, step S006, step S009, step S0012, in the Preset Time after
N2In second, the waste liquid in reaction cup is exhausted.So, adsorption effect is improve, the probability of magnetic bead loss is reduced.Preferably, N2=
3.Certainly, N also may be selected2It is other numerical value, such as N2=2, the embodiment of the present invention is not limited this.
Preferably, in above-mentioned steps S004, step S007, step S0010, the preceding N in Preset Time1In second, to anti-
Answer injection cleaning fluid in cup.
In order to improve Blending Efficiency of Blending, in above-mentioned steps S004, step S007, step S0010, cleaning fluid injection completes N3Second
Afterwards, the liquid and magnetic bead of reaction cup are mixed, N is mixed4Stop mixing after second, stop mixing N5Mixed again after second, N is mixed again6
Terminate to mix after second.It is understood that N1、N3、N4、N5、N6Sum is less than Preset Time.Preferably, N3=1-2, N4=2-3, N3
= N5, N4= N6.Certainly, N also may be selected3、N4、N5、N6It is other numerical value, it is not limited to this.
The time and mixing time for being usually injected into cleaning fluid are less than Preset Time, in order to reduce the probability of magnetic bead loss, on
Stating step S004, step S007 and step S0010 also includes step：After mixing terminates, the magnetic bead in adsorption reaction cup.
In the method for above-mentioned Magneto separate cleaning, step S0013 is also included after step S006 or step S0012：Will be to
Reaction cup moves to the first station 1, and reaction cup is taken away.
It is understood that above-mentioned first station 1 is picks and places station.
For picking and placeing for reaction cup, can manually pick and place, can also be picked and placeed using handgrip or manipulator, the present invention is implemented
Example is not limited this.
In the method for above-mentioned Magneto separate cleaning, station is picked and placeed by setting up, facilitate picking and placeing for reaction cup, it also avoid taking
Influence of the reaction cup to other stations is put, Magneto separate efficiency is improve.
In the method for above-mentioned Magneto separate cleaning, due to there is liquid in the reaction cup by reaction, then noted in step S001
The cleaning fluid volume for entering is less than the cleaning fluid volume injected in step S004 steps S007, step S0010.
Preferably, the cleaning fluid volume injected in step S001 is 200 μ L；In step S004, step S007, step S0010
The cleaning fluid volume of injection is 400 μ L.Certainly, the cleaning fluid volume that injection also may be selected is other numerical value, it is not limited to this.
In order to improve separating effect, in the method for above-mentioned Magneto separate cleaning, also included before step S11 and step S21
Step：Storehouse and/or heated wash liquid are held in heating, wherein, holding storehouse is used to accommodate reaction cup.So so that the reagent in reaction cup
Can continue to react during Magneto separate with sample, so as to improve Magneto separate effect.
For mode of heating, the embodiment of the present invention is not limited this.
The method of above-mentioned Magneto separate cleaning, by the fluid emptying that will be remained in fluid injection pipeline and injection needle so that heating
Cleaning fluid afterwards is full of fluid injection pipeline and injection needle, is easy to ensure the temperature of liquid in reaction cup, so as to improve Magneto separate effect.
In order to more specifically illustrate the present invention, the method for the Magneto separate cleaning that the embodiment of the present invention three is provided includes step
Suddenly：
Step S31：Start Magneto separate cleaning；
Step S32：Storehouse and cleaning fluid are held in heating, and transhipment part 14 goes to pipeline filling position（Storage configuration position）, will note
The filling pipe 15 that extraction raffinate and/or gas injection transhipment part 14 in liquid pipeline and injection needle is carried（Storage configuration）It is interior, then by
Aspirating needle is taken away, is carried out continuously 15 times, and the gas and extraction raffinate that are remained in fluid injection pipeline and injection needle are drained, and is made in fluid injection pipeline
Portion is full of new cleaning fluid（Cleaning fluid after being heated）；
Step S33：Transhipment part 14 resets to and picks and places station（First station 1）If reset has deviation or the failure that resets, and stops
Machine is alarmed；
Step S34：Handgrip is loaded into during the reaction cup of sample and reagent grabs the displacement structure in the first station 1, reflective
Photoelectric sensor determines whether that reaction cup enters the first station 1, if crawl failure, stopping alarm, reaction cup enters the
After one station 1, start Magneto separate cleaning；
Step S35：Reaction cup is transferred to the second station 2, and stops 12s in the second station 2, and the first injection needle declines in preceding 2s, and
The μ L of cleaning fluid 200 are injected to reaction cup, the second station 2 has magnet adsorption；
Step S36：Reaction cup is transferred to 3rd station 3, and stops 12s in 3rd station 3, and 3rd station 3 has magnet adsorption；
Step S37：Reaction cup is transferred to the 4th station 4, and stops 12s in the 4th station 4, and the aspirating needles of last 2s first decline exhaustion
Waste liquid, the 4th station 4 has magnet adsorption, completes to clean for the first time；
Step S38：Reaction cup is transferred to the 5th station 5, and stops 12s in the 5th station 5, and it is clear that the injection needles of preceding 2s second decline injection
The μ L of washing lotion 400, then wait 1s, mix 2s, stop 1s, then mix 2s, stop 5s, the absorption of the non-magnet of the 5th station 5；
Step S39：Reaction cup is transferred to the 6th station 6, and stops 12s in the 6th station 6, and the 6th station 6 has magnet adsorption；
Step S310：Reaction cup is transferred to the 7th station 7, and stops 12s in the 7th station 7, and the aspirating needles of last 2s second decline to be inhaled
Most waste liquid, the 7th station 7 has magnet adsorption, completes second and cleans；
Step S311：Reaction cup is transferred to the 8th station 8, and stops 12s in the 8th station 8, and the injection needles of preceding 2s the 3rd decline injection
The μ L of cleaning fluid 400, then wait 1s, mix 2s, stop 1s, then mix 2s, stop 5s, the absorption of the non-magnet of the 8th station 8；
Step S312：Reaction cup is transferred to the 9th station 9, and stops 12s in the 9th station 9, and the 9th station 9 has magnet adsorption；
Step S313：Reaction cup is transferred to the tenth station 10, and the tenth station 10 stops 12s, and the aspirating needles of last 2s the 3rd decline to be inhaled
Most waste liquid, the tenth station 10 has magnet adsorption, completes third time and cleans；
Step S314：Reaction cup is transferred to the 11st station 11, and the 11st station 11 stops 12s, and the injection needles of preceding 2s the 4th decline
The injection μ L of cleaning fluid 400, then wait 1s, mix 2s, stop 1s, then mix 2s, stop 5s, and the non-magnet of the 11st station 11 is inhaled
It is attached；
Step S315：Reaction cup is transferred to twelve-station 12, and stops 12s in twelve-station 12, and the twelve-station 12 has
Magnet adsorption；
Step S316：Reaction cup is transferred to the 13rd station 13, and stops 12s, the aspirating needles of last 2s the 4th in the 13rd station 13
Decline and exhaust waste liquid, the 13rd station 13 has magnet adsorption, complete the 4th cleaning；
Step S317：Reaction cup is transferred to the first station 1, is taken away by handgrip.
It should be noted that filling pipe 15 is storage configuration, the first station 1 is and picks and places station.
Be can be seen that by the above method, only just realize that four cleanings are separated with 13 stations, the increase of wash number makes
Pattern detection is more accurate.The reduction of hole position is cleaned, the volume of the system of Magneto separate cleaning is substantially reduced, makes what Magneto separate was cleaned
System suitability is stronger, and about 2.5 minutes sample used times can complete four cleanings, save Magneto separate scavenging period.Mix stirring
Work station work is mixed by being individually once changed to each twice, improve cleaning performance.Magneto separate cleaning coordinates compact, flow letter
It is single, there is no unnecessary losing time, it is easy to accomplish Automated condtrol.
On the premise of volume is allowed, the station that can be cleaned each Magneto separate increases a station, makes magnet adsorption
Time increases, and further reduces magnetic bead losing probability；Also magnet position can be set in even mixed position, magnetic is increased using remaining time is mixed
Iron is adsorbed；Preset Time can also be increased, the effect of Magneto separate cleaning is improved.
The method of the Magneto separate cleaning provided based on above-described embodiment, it is clear that the embodiment of the present invention additionally provides a kind of Magneto separate
The device washed, the device of Magneto separate cleaning includes：First control unit, the second control unit and the 3rd control unit.
Above-mentioned first control unit is used to control cleaning fluid to import fluid injection pipeline and injection needle；Second control unit is used to control
The liquid made from injection needle discharge is flow in storage configuration and for controlling aspirating needle to siphon away the liquid in storage configuration；When
After cleaning fluid is full of fluid injection pipeline and injection needle, above-mentioned 3rd control unit is used to control cleaning fluid to enter the magnetic bead in reaction cup
Row Magneto separate is cleaned.
Can be air and liquid, or liquid, the liquid from the fluid of injection needle discharge during cleaning fluid is imported
Only include the cleaning fluid for importing including the liquid remained in injection needle and fluid injection pipeline and the cleaning fluid of importing or the liquid.
Above-mentioned second control unit is used to control the liquid from injection needle discharge to flow in storage configuration and for controlling aspirating needle to inhale
Walk the liquid in storage configuration, it is to avoid from the liquid influence Magneto separate cleaning of injection needle discharge.
With the importing of cleaning fluid, the fluid discharge that will be remained in fluid injection pipeline and injection needle.When cleaning fluid is full of fluid injection
When pipeline and injection needle, show the fluid of residual in fluid injection pipeline and injection needle by emptying, it is to avoid fluid injection pipeline and injection needle
The fluid influence reservoir quantity of interior residual, then now can carry out Magneto separate cleaning to the magnetic bead in reaction cup.
The device of Magneto separate provided in an embodiment of the present invention cleaning, sets the first control unit, the second control unit and the
Three control units, realize before the magnetic bead in reaction cup carries out Magneto separate cleaning, allow the cleaning fluid of importing to be full of fluid injection
Pipeline and injection needle, then realize the fluid emptying that will be remained in fluid injection pipeline and injection needle, it is to avoid fluid injection pipeline and injection needle
The fluid influence reservoir quantity of interior residual, also allows for ensureing reservoir quantity, improves cleaning performance；Meanwhile, will be discharged from injection needle certainly
Liquid drain into storage configuration, siphon away the liquid in storage configuration using aspirating needle, it is to avoid from the liquid of injection needle discharge
Influence the Magneto separate cleaning of reaction cup.
In the device of above-mentioned Magneto separate cleaning, mode of the cleaning fluid full of fluid injection pipeline and injection needle is determined, exist various.
For example, can be compared by the capacity sum of the import volume of cleaning fluid and fluid injection pipeline and injection needle, or by from injection needle
The amount of liquid of discharge is determined.
Determine for convenience, the device of above-mentioned Magneto separate cleaning also includes determining unit, when the import volume of cleaning fluid is more than
During the capacity sum of fluid injection pipeline and injection needle, determining unit is used to determine that cleaning fluid is full of fluid injection pipeline and injection needle.
Certainly, also may be selected when the import volume of cleaning fluid is equal to the capacity sum of fluid injection pipeline and injection needle, it is determined that single
Unit determines that cleaning fluid is full of fluid injection pipeline and injection needle, it is not limited to above-described embodiment.
In actual application, cleaning fluid imports fluid injection pipeline and the importing number of times of injection needle is more, and emptying effect is got over
It is good.For the ease of the fluid emptying that will be remained in fluid injection pipeline and injection needle, above-mentioned first control unit is specially：For controlling
Cleaning fluid imports fluid injection pipeline and injection needle at least twice.For the concrete numerical value for importing number of times, set according to actual needs
Meter, for example import number of times be 15 times or import number of times be 14 times or import number of times be it is 16 inferior, the embodiment of the present invention to it not
Limit.
Specifically, importing number of times and n >=2 of the n for cleaning fluid, a is the single import volume of cleaning fluid, the then importing of cleaning fluid
It is a*n to measure.
Preferably, the device of above-mentioned Magneto separate cleaning also includes：4th control unit, the first detection unit, the 5th control
Unit and the second detection unit.
Wherein, the 4th control unit is used to control transhipment part 14 to move；First detection unit is used to detect to be located at transports
Whether the displacement structure of the initial bit of part 14 reaches and picks and places station；Taken when the displacement structure positioned at the transhipment initial bit of part 14 is reached
When putting station, the 5th control unit picks and places the displacement structure of station for controlling reaction cup to move to；Second detection unit is used for
Detection picks and places whether station has reaction cup.
Above-mentioned 3rd control unit specifically for：After cleaning fluid is full of fluid injection pipeline and injection needle, and picks and places station and have
During reaction cup, control carries out Magneto separate cleaning to the magnetic bead in reaction cup.
In order to improve security reliability, the device of above-mentioned Magneto separate cleaning also includes：First protection location and the second protection
Unit；Wherein, when the displacement structure for transporting the initial bit of part 14 is not reached picks and places station, the first protection location is used to perform report
Alert action and/or shutdown action；When the reactionless cup of station is picked and placeed, the second protection location is used to perform actuation of an alarm and/or stop
Motor-driven work.
Above-mentioned first protection location is alarm or power switch, and above-mentioned second protection location is that alarm or power supply are opened
Close.
Above-mentioned power switch can be the master switch of the system of whole Magneto separate cleaning, also can be only control transhipment part motion
Power switch.Above-mentioned alarm can be alarm lamp, or buzzer or other warning pieces.The embodiment of the present invention is to alarm
The particular type of device and power switch is not limited.
Specifically, the liquid discharged from injection needle is drained into storage configuration and storage configuration is siphoned away using aspirating needle
, there are various implementations in interior liquid, for example, injection needle is moved at storage configuration so that injection needle and storage configuration pair
Together, the liquid from injection needle discharge is flowed directly into storage configuration；Aspirating needle is moved into storage configuration, by the motion of aspirating needle
Liquid in storage configuration is siphoned away.Certainly, also may be selected to connect injection needle and storage configuration using mozzle and interests are led
Flow tube connects aspirating needle and storage configuration, or mobile storage configuration to realize above-mentioned functions, it is not limited to above-described embodiment.
In order to simplify structure, be easy to implement, the second control unit specifically for：Control injection needle moves to the top of storage configuration
Hold so that injection needle it is relative with storage configuration with realize from injection needle discharge liquid drain into storage configuration, control aspirating needle shifting
The liquid in storage configuration is siphoned away to storage configuration and control aspirating needle.
In order to simplify structure, above-mentioned storage configuration is arranged on transhipment part, and the transhipment part drives reaction cup motion.
Above-mentioned storage configuration can be holding tank or filling pipe 15, or accommodate tank etc., and the embodiment of the present invention is not done to this
Limit.
The device of the Magneto separate cleaning provided based on above-described embodiment, it is clear that the embodiment of the present invention additionally provides a kind of Magneto separate
The equipment washed, the equipment of Magneto separate cleaning includes：Memory and processor.
Above-mentioned memory is used to store the data produced in application program and application program running；
Above-mentioned processor is used to perform application program, realizes following functions：Control cleaning fluid imports fluid injection pipeline and injection needle, control
The liquid made from injection needle discharge is drained into storage configuration, and control aspirating needle siphons away the liquid in storage configuration, when cleaning fluid fills
When full fluid injection pipeline and injection needle, for controlling cleaning fluid to carry out Magneto separate cleaning to the magnetic bead in reaction cup.
The equipment of Magneto separate cleaning provided in an embodiment of the present invention, sets memory and processor, realizes to reaction
Before magnetic bead in cup carries out Magneto separate cleaning, allow the cleaning fluid of importing to be full of fluid injection pipeline and injection needle, then realize fluid injection
The fluid emptying of residual in pipeline and injection needle, it is to avoid the fluid influence reservoir quantity of residual in fluid injection pipeline and injection needle,
It is easy to ensure reservoir quantity, improves cleaning performance；Meanwhile, from the liquid discharged from injection needle is drained into storage configuration, use
Aspirating needle siphons away the liquid in storage configuration, it is to avoid from the Magneto separate cleaning of the liquid influence reaction cup of injection needle discharge.
The equipment of the Magneto separate cleaning provided based on above-described embodiment, it is clear that the embodiment of the present invention additionally provides a kind of Magneto separate
The system washed, the system of Magneto separate cleaning includes the equipment of the Magneto separate cleaning described in above-described embodiment.
Because the equipment of above-mentioned Magneto separate cleaning has above-mentioned technique effect, Magneto separate cleaning provided in an embodiment of the present invention
The system equipment with the cleaning of above-mentioned Magneto separate, then the system of above-mentioned Magneto separate cleaning also there is corresponding technique effect, this
Text is repeated no more.
In the system of above-mentioned Magneto separate cleaning, storage configuration can be a single part or structure, may also set up in magnetic
In the system of separation cleaning on existing part.In order to simplify structure, convenient use, it is clear that above-mentioned storage configuration is arranged at Magneto separate
On transhipment part 14 in the system washed, the transhipment part 14 is used for placing response cup and is moved with the reaction cup.So, lead to
Cross transhipment part 14 and carry storage configuration, pipeline or structure are set without extra, the system for simplifying whole Magneto separate cleaning
Structure.
Preferably, above-mentioned storage configuration is storage tank or filling pipe 15.Certainly, storage configuration also may be selected for other are tied
Structure, it is not limited to this.
Further, above-mentioned storage configuration at least two, and along the direction of motion setting of transhipment part 14.Certainly, deposit
Put structure or one, it is not limited to above-described embodiment.
It should be noted that transhipment part 14 is provided with the displacement structure for placing response cup, the displacement structure is at least
Two, and along the direction of motion setting of transhipment part 14.
For the ease of using, above-mentioned storage configuration and the alternate setting of displacement structure.
As shown in figure 3, transhipment part 14 is provided with 13 displacement structures and 13 storage configurations, the storage configuration is filling
Pipe 15.Specifically, displacement structure and the first station 1, the second station 2,3rd station 3, the 4th station 4, the 5th station the 5, the 6th
Station 6, the 7th station 7, the 8th station 8, the 9th station 9, the tenth station 10, the 11st station 11, twelve-station the 12, the tenth
Three stations 13 are corresponded.There is a filling pipe 15 between two adjacent displacement structures.
In actual mechanical process, reaction cup is moved in the system of Magneto separate cleaning from incubation storehouse, is incubated storehouse and be ensure that instead
Answer temperature.But, the sample and reagent unreacted existed when reaction cup is left in it are complete.In order to improve Magneto separate effect, need
The complete sample of unreacted and reagent is set to continue reaction during Magneto separate.Specifically, the system of above-mentioned Magneto separate cleaning
Also include：Heating hold storehouse primary heater, and/or heated wash liquid secondary heater.
Ensure that the sample and reagent of reaction cup are in reaction temperature by heating response cup or cleaning fluid, so that after
It is continuous to react, the probability that tested substance is sucked away is reduced, improve Magneto separate effect；Meanwhile, before fluid injection, will note
The fluid emptying of residual, further increases Magneto separate cleaning performance in liquid pin and fluid injection pipeline.
For primary heater and the type and structure of secondary heater, it is designed according to actual needs, the present invention is real
Example is applied not limit this.
The foregoing description of the disclosed embodiments, enables those skilled in the art to realize or uses the present invention.To this
Various modifications of a little embodiments will be apparent for a person skilled in the art, and generic principles defined herein can
Without departing from the spirit or scope of the present invention, to realize in other embodiments.Therefore, the present invention will not be limited
It is formed on the embodiments shown herein, and is to fit to consistent with principles disclosed herein and features of novelty most wide
Scope.
Claims (16)
1. a kind of method that Magneto separate is cleaned, it is characterised in that including step：
Cleaning fluid is imported into fluid injection pipeline and injection needle；
The liquid discharged from the injection needle is drained into storage configuration, the liquid in the storage configuration is siphoned away using aspirating needle
Body；
When the cleaning fluid is full of the fluid injection pipeline and the injection needle, Magneto separate is carried out to the magnetic bead in reaction cup clear
Wash.
2. method according to claim 1, it is characterised in that determine the cleaning fluid full of the fluid injection pipeline and described
The process of injection needle includes step：
When the import volume of the cleaning fluid is more than the capacity sum of the fluid injection pipeline and the injection needle, the cleaning fluid fills
Full the fluid injection pipeline and the injection needle.
3. method according to claim 1, it is characterised in that the cleaning fluid is imported into the fluid injection pipeline and the note
The importing number of times of liquid pin is at least twice.
4. method according to claim 1, it is characterised in that also wrapped before being cleaned to the magnetic bead in the reaction cup
Include step：
Control transhipment part motion, when the displacement structure positioned at the transhipment part initial bit is reached picks and places station, will react
Cup is placed on the displacement structure that station is picked and placeed described in arrival.
5. method according to claim 4, it is characterised in that also including step：
When the displacement structure do not reach it is described pick and place station when, then alarm and/or shut down；
When the station that picks and places is without the reaction cup, then alarms and/or shut down.
6. the method according to any one in claim 1-5, it is characterised in that the liquid that will be discharged from the injection needle
Drain into the storage configuration, specifically include step：The injection needle is moved into the top of the storage configuration so that the note
Liquid pin is relative with the storage configuration；
Liquid in the storage configuration is siphoned away using aspirating needle, step is specifically included：The aspirating needle is moved into the storage
Structure is so that the aspirating needle draws the liquid in the storage configuration.
7. the device that a kind of Magneto separate is cleaned, it is characterised in that including：
First control unit, for controlling cleaning fluid to import fluid injection pipeline and injection needle；
Second control unit, for controlling the liquid from injection needle discharge to flow in storage configuration and being inhaled for control
Liquid pin siphons away the liquid in the storage configuration；
3rd control unit, when the cleaning fluid is full of the fluid injection pipeline and the injection needle, for controlling the cleaning
Liquid carries out Magneto separate cleaning to the magnetic bead in reaction cup.
8. device according to claim 7, it is characterised in that also include：
Determining unit, when the import volume of the cleaning fluid is more than the capacity sum of the fluid injection pipeline and the injection needle, uses
In it is determined that the cleaning fluid is full of the fluid injection pipeline and the injection needle.
9. device according to claim 7, it is characterised in that first control unit is specially：It is described for controlling
Cleaning fluid imports the fluid injection pipeline and the injection needle at least twice.
10. device according to claim 7, it is characterised in that also include：
4th control unit, for controlling transhipment part motion；
First detection unit, station is picked and placeed for detecting whether the displacement structure positioned at the transhipment part initial bit reaches；
5th control unit, it is anti-for controlling when the displacement structure positioned at the transhipment part initial bit is reached picks and places station
Cup is answered to move to described picking and placeing on the displacement structure of station；
Second detection unit, described picks and places whether station has the reaction cup for detecting；
Wherein, the 3rd control unit specifically for：After the cleaning fluid is full of the fluid injection pipeline and the injection needle,
And it is described when picking and placeing station and having the reaction cup, control carries out Magneto separate cleaning to the magnetic bead in reaction cup.
11. devices according to claim 10, it is characterised in that also include：
First protection location, when the displacement structure of the transhipment part initial bit do not reach it is described pick and place station when, for performing
Actuation of an alarm and/or shutdown action；
Second protection location, when it is described pick and place station without the reaction cup when, for performing actuation of an alarm and/or shutdown action.
12. device according to any one in claim 7-11, it is characterised in that second control unit is specifically used
In：The injection needle is controlled to move to the top of the storage configuration so that the injection needle is relative with the storage configuration, control
The liquid that the aspirating needle moves to the storage configuration and controls the aspirating needle to siphon away in the storage configuration.
A kind of 13. equipment of Magneto separate cleaning, it is characterised in that including：
Memory, for storing application program and the application program running in produce data；
Processor, for performing the application program, realizes following functions：Control cleaning fluid imports fluid injection pipeline and injection needle,
The liquid from injection needle discharge is controlled to drain into storage configuration, control aspirating needle siphons away the liquid in the storage configuration,
When the cleaning fluid is full of the fluid injection pipeline and the injection needle, for controlling the cleaning fluid to the magnetic bead in reaction cup
Carry out Magneto separate cleaning.
14. a kind of systems of Magneto separate cleaning, it is characterised in that including equipment as claimed in claim 13.
15. systems according to claim 14, it is characterised in that the storage configuration is arranged at the Magneto separate cleaning
On the transhipment part of system, the transhipment part is used to place the reaction cup.
16. systems according to claim 15, it is characterised in that the storage configuration at least two, and the storage
The alternate setting of displacement structure of structure and the transhipment part, the displacement structure is used to place the reaction cup.
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| CN201710233164.2A CN106824890A (en) | 2017-04-11 | 2017-04-11 | Method, device, equipment and system that Magneto separate is cleaned |
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| CN201710233164.2A CN106824890A (en) | 2017-04-11 | 2017-04-11 | Method, device, equipment and system that Magneto separate is cleaned |
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| CN107377563A (en) * | 2017-08-24 | 2017-11-24 | 深圳市亚辉龙生物科技股份有限公司 | Magneto separate cleaning device and its method of work and fluid injection needle tubing |
| CN108704765A (en) * | 2018-06-29 | 2018-10-26 | 河源市东源鹰牌陶瓷有限公司 | Slurry sieving iron removal system |
| CN109406810A (en) * | 2017-08-16 | 2019-03-01 | 北京普利生仪器有限公司 | Sample analysis apparatus, sample incubation device and its control method |
| CN110082549A (en) * | 2018-01-25 | 2019-08-02 | 深圳市新产业生物医学工程股份有限公司 | Cleaning device and chemiluminescence detector |
| CN110125076A (en) * | 2018-02-08 | 2019-08-16 | 成都深迈瑞医疗电子技术研究院有限公司 | Magnetic bead cleans separator, magnetic bead cleaning separation method and chemical illumination immunity analysis instrument |
| CN110487998A (en) * | 2019-08-13 | 2019-11-22 | 迈克医疗电子有限公司 | Parameter optimization method and device, analysis instrument, the storage medium of magnetic separation system |
| CN110823669A (en) * | 2019-11-08 | 2020-02-21 | 广州科方生物技术股份有限公司 | Magnetic separation cleaning method |
| CN114618849A (en) * | 2020-12-11 | 2022-06-14 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for magnetic separation reaction cup and sample analysis device |
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| CN109406810A (en) * | 2017-08-16 | 2019-03-01 | 北京普利生仪器有限公司 | Sample analysis apparatus, sample incubation device and its control method |
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| CN110487998A (en) * | 2019-08-13 | 2019-11-22 | 迈克医疗电子有限公司 | Parameter optimization method and device, analysis instrument, the storage medium of magnetic separation system |
| CN110823669A (en) * | 2019-11-08 | 2020-02-21 | 广州科方生物技术股份有限公司 | Magnetic separation cleaning method |
| CN114618849A (en) * | 2020-12-11 | 2022-06-14 | 深圳市帝迈生物技术有限公司 | Cleaning device and cleaning method for magnetic separation reaction cup and sample analysis device |
| CN114618849B (en) * | 2020-12-11 | 2023-07-18 | 深圳市帝迈生物技术有限公司 | Cleaning device, cleaning method and sample analysis device for magnetic separation reaction cup |
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Address after: 610041 4 Building 8, two road, Chengdu, Sichuan Applicant after: Mike Medical Electronics Ltd Address before: 610041, No. 1, 5 buildings, 16 Chengdu, hi tech Zone, Sichuan, China Applicant before: SICHUAN MAKER BIOMEDICAL ELECTRONIC CO., LTD. |
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