CN106822841A - It is a kind of to treat medicine of asthma and preparation method thereof - Google Patents
It is a kind of to treat medicine of asthma and preparation method thereof Download PDFInfo
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- CN106822841A CN106822841A CN201710121996.5A CN201710121996A CN106822841A CN 106822841 A CN106822841 A CN 106822841A CN 201710121996 A CN201710121996 A CN 201710121996A CN 106822841 A CN106822841 A CN 106822841A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8884—Arisaema, e.g. Jack in the pulpit
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Alternative & Traditional Medicine (AREA)
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Abstract
Medicine of asthma and preparation method thereof is treated the invention discloses a kind of, it is mainly and is prepared from according to a certain weight ratio by borneol, rhizoma arisaematis, ginseng, balloonflower root, tussilago, rhizoma zingiberis, Radix Glycyrrhizae, medicine of the present invention has opens facilitaing lung gas, eliminating the phlegm apocenosis, qi-regulating moistening lung, reinforces vital energy, Gu the de- function of promoting the production of body fluid, for treating asthma and pure alopecia instant effect, good effect does not recur.
Description
Technical field
Medicine of asthma and preparation method thereof is treated the present invention relates to a kind of, belongs to the field of Chinese medicines.
Background technology
Modern medicine thinks that asthma is the chronic airway inflammation participated in by various kinds of cell and cellular component.Traditional Chinese medicine is then recognized
For this disease is lied prostrate mainly due in phlegm and retained fluid, wind-cold affecting lung, and phlegm wet stops up resistance, caused by impairment of dispersing and descending function of the lung.At present, because Western medicine cannot have
Effect treatment asthma, therefore there is great demand to the Chinese medicine of effectively treatment asthma in people, up to now, it has not been found that
Relevant report on medicine of the present invention.
The content of the invention
The present inventor has been successfully found effective treatment finally according to the checking repeatedly of research and the clinical test of theory of traditional Chinese medical science
The medicine of asthma, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effective treatment asthma.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is to select borneol, rhizoma arisaematis, ginseng, balloonflower root, tussilago, rhizoma zingiberis, Radix Glycyrrhizae, perilla leaf, honey to enter
Row combines what is prepared, these drug regimens is caused into each efficacy of drugs produces synergy such that it is able to effectively treat asthma
Recurrence.It is cool wherein from borneol because its nature and flavor is arduous, enter the heart, lung channel, there are logical all keys, stagnated fire is dissipated, screen improving eyesight is gone, subside a swelling
The function of analgesic, controls apoplexy lockjaw, pyreticosis coma , Jing Epilepsy phlegm fans, deafness with qi stagnation, larynx numbness, aphtha, tympanitis, carbuncle swells, hemorrhoid,
Conjunctivitis, enterobiasis.It is poisonous from rhizoma arisaematis because its nature and flavor toil, warm, enter lung, liver, the spleen channel, have eliminating dampness and eliminating phlegm, dispel
Wind is calmed the frightened, the function of dispersing swelling and dissipating binds, controls heap soil or fertilizer over and around the roots of apoplexy phlegm, and Kou Yan wo are oblique, hemiplegia , Dian Epilepsy, infantile convulsion, lockjaw, anemophlegmatic vertigo,
Larynx numbness, scrofula, carbuncle swells are fallen and flutter injured, snake bite and insect sting.From ginseng because its property sweet and slightly bitter taste, temperature, enter spleen, lung channel, there is big
Tonifying primordial Qi, promotes the production of body fluid Gu de-, the function of calming the nerves, and controls that internal lesion caused by overexertion is deficient, and food is told in deficiency of food, burnout, gastric disorder causing nausea, and lingering diarrhea of defecating, empty cough and asthma promotees, oneself
Sweat is taken off cruelly, and palpitation with fear, forgetful, dizziness and headache, impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, and children shy and not multiple, all qi and bloods empty long slowly
The disease that body fluid deficiency.From balloonflower root because its nature and flavor toil, put down, enter lung, stomach, there is out facilitaing lung gas, the function of eliminating the phlegm apocenosis,
Control exogenous cough, abscess of throat, lung carbuncle pyemesis, fullness in the chest and hypochondriac pain, dysentery stomachache.From tussilago because its nature and flavor is pungent, temperature enters
Lung channel, there is moistening lung to lower qi, and resolving sputum stops the function of coughing, control cough it is inverse pant, larynx numbness.From rhizoma zingiberis because its nature and flavor is pungent, heat enters
Spleen, stomach, lung channel, have middle benefit gas by trembling with fear, and the function of Back to Yang Tongmai controls trusted subordinate's crymodynia, vomits and diarrhoea, and cold weak pulse of limb, cold drink is breathed with cough, and chill is wet
Numbness, the deficiency of yang is told, is defeated in battle, lower blood.From Radix Glycyrrhizae because its property sweet taste, enters spleen, stomach, lung channel, have and detoxify with middle emergency, moistening lung,
The function of coordinating the drug actions of a prescription, processs, deficiency of food weakness of the spleen and the stomach with controlling, loose stool of suffering from abdominal pain, overstrain heating, consumptive lung disease cough, and palpitaition shies carbuncle, raw to use
Control abscess of throat, peptic ulcer, ulcer sores, antidote poison and food poisoning.From perilla leaf because its nature and flavor is pungent, temperature,
Enter lung, the spleen channel, deliver, cold dispelling, qi-regulating, and the function of seeking, cure cold chill, fever with aversion to cold, cough, asthma, fullness and oppression of chest and abdomen,
Fetal irritability, and can solving toxin of fish and crab.From honey because its nature and flavor is sweet, put down, enter lung, spleen, large intestine channel, there is bowl spares, moisturize, only
Bitterly, the function of removing toxic substances, controls xeropulmonary cough, and dry constipation of intestines, gastral cavity pain, nasosinusitis, aphtha, the burning hot wound of soup solves Aconitum Carmichaeli.
Specific embodiment
The drug dose of instant component is also that inventor summarizes what is drawn by largely groping, and the consumption of each component is following heavy
All there is preferable curative effect in the range of amount：
3-7 grams of borneol, 15-20 grams of rhizoma arisaematis, 10-15 grams of ginseng, 15-25 grams of balloonflower root, 10-20 grams of tussilago, 5-15 grams of rhizoma zingiberis,
20-30 grams of Radix Glycyrrhizae, 15-25 grams of perilla leaf, 93-147 grams of honey.
Preferably
5 grams of borneol, 18 grams of rhizoma arisaematis, 12 grams of ginseng, 20 grams of balloonflower root, 15 grams of tussilago, 10 grams of rhizoma zingiberis, 25 grams of Radix Glycyrrhizae, perilla leaf
20 grams, 145 grams of honey.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, borneol：Original is used as medicine；
2nd, rhizoma arisaematis：Impurity is picked, ash bits are cleaned, dried；
3rd, ginseng：Except removing LU, segment；
4th, balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；
5th, tussilago：Pick stubble, sandstone, soil block；
6th, rhizoma zingiberis：Net impurity is picked, is soaked in water 3-6 hours, pulled out, cut into slices or dice after vexed profit, dried；
7th, Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing；
8th, perilla leaf：Impurity is picked, is dried；
9th, honey：Extract according to quantity.
2nd, prepare
1st, rhizoma arisaematis, ginseng, balloonflower root, tussilago, rhizoma zingiberis, Radix Glycyrrhizae, the perilla leaf mixing and stirring that will be cooked, grind with borneol
For fine powder crosses 200 mesh dusting covers；
The 2nd, honey refined into 110-115 DEG C of tender honey；
3rd, the spice by weight 1 for fine powder will be ground：1 ratio adds mixing system in honey to stick together, then rubbing pill, per 6 grams of ball.
Medicine of the present invention has opens facilitaing lung gas, and eliminating the phlegm apocenosis, qi-regulating moistening lung is reinforced vital energy, Gu the de- function of promoting the production of body fluid, is used for
Treat asthma instant effect, good effect, do not recur.
Balloonflower root has out facilitaing lung gas in prescription, and the function of eliminating the phlegm apocenosis is monarch drug in a prescription, and rhizoma arisaematis is eliminating dampness and eliminating phlegm, and dispelling wind and relieving convulsion disappears
Swollen dissipating bind, perilla leaf are delivered, cold dispelling, qi-regulating, and battalion, and the two is ministerial drug；Three taste medicines are played and open facilitaing lung gas jointly, eliminating the phlegm apocenosis,
Dispelling wind and relieving convulsion, dispersing swelling and dissipating binds, the effect of qi-regulating, treatment asthma effect comprehensively, and to open facilitaing lung gas, eliminating the phlegm apocenosis, based on qi-regulating
Can effect a permanent cure.Ginseng reinforces vital energy, Gu de- promote the production of body fluid, it is adjutant to calm the nerves；Radix Glycyrrhizae and middle emergency, moistening lung, removing toxic substances, coordinating the drug actions of a prescription control spleen
Stomach is weak, consumptive lung disease cough, and, to make medicine, all medicines are to take stopgap measures with being left, and said medicine is combined, and are allowed to medicine for antidote poison and food poisoning
Thing effect produces synergy such that it is able to the effectively recurrence for the treatment of asthma.
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these experiments include medicine of the present invention
Animal toxicity test and clinical observation on the therapeutic effect experiment.
The animal toxicity test of [test example 1] medicine of the present invention
West Germany rabbit 30 is taken, male and female dual-purpose, body weight 2.0-2.5kg is divided into two groups, and one of which is overdose, another group for just
Constant, takes pill overdose group 0.25g/kg, normal amount group 0.15g/kg, is administered using dilution administration by gavage, twice a day, even
Continuous to take 7 days, as a result observation administration reaction shows that rabbit activity, diet are normal, and medicine is without bad toxic and side effect.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept out-patient totally 26 for medical treatment.
2nd, diagnostic criteria
Asthma clinical is presented with：Feeling of oppression and pain in the chest, cough is coughed up phlegm, expiratory dyspnea repeated relapsing cough etc..
3rd, treatment method
Daily respectively to take 2 balls sooner or later, 10 days courses for the treatment of take medicine continuously 3 courses for the treatment of.
4th, efficacy assessment standard
It is effective：SOA disappears, and constitution recovers normal, recovery from illness.
Take a turn for the better：Patient's feeling of oppression and pain in the chest, cough is coughed up phlegm, and dyspneic symptom is clearly better, and system progressively recovers normal.
It is invalid：Improvement standard person is not reached.
5th, treatment results（See the table below）：
In above-mentioned treatment, with drug therapy asthmatic patient of the present invention 26, as a result effective 20, obvious effective rate is 76.92%, good
Turn 5, improvement rate is 19.23%, and invalid 1, total effective rate is 95.15%.
Claims (3)
1. a kind of medicine for treating asthma, it is characterised in that：It is made up of the bulk drug in following weight range：
3-7 grams of borneol, 15-20 grams of rhizoma arisaematis, 10-15 grams of ginseng, 15-25 grams of balloonflower root, 10-20 grams of tussilago, 5-15 grams of rhizoma zingiberis,
20-30 grams of Radix Glycyrrhizae, 15-25 grams of perilla leaf, 93-147 grams of honey.
2. medicine according to claim 1, wherein the consumption of each bulk drug is：
5 grams of borneol, 18 grams of rhizoma arisaematis, 12 grams of ginseng, 20 grams of balloonflower root, 15 grams of tussilago, 10 grams of rhizoma zingiberis, 25 grams of Radix Glycyrrhizae, perilla leaf
20 grams, 145 grams of honey.
3. the preparation method of medicine according to claim 1 or claim 2, it is characterised in that：It comprises the following steps：
（One）Get the raw materials ready
（1）Borneol：Original is used as medicine；
（2）Rhizoma arisaematis：Impurity is picked, ash bits are cleaned, dried；
（3）Ginseng：Except removing LU, segment；
（4）Balloonflower root：Net impurity is picked, except removing LU, is cleaned and is pulled out, cut into slices after running through, dried；
（5）Tussilago：Pick stubble, sandstone, soil block；
（6）Rhizoma zingiberis：Net impurity is picked, is soaked in water 3-6 hours, pulled out, cut into slices or dice after vexed profit, dried；
（7）Radix Glycyrrhizae：Pick impurity, clean, be soaked in water to eighty per cant it is saturating when, pull out, run through, cut into slices, airing；
（8）Perilla leaf：Impurity is picked, is dried；
（9）Honey：Extract according to quantity；
（Two）Prepare
（1）Rhizoma arisaematis, ginseng, balloonflower root, tussilago, rhizoma zingiberis, Radix Glycyrrhizae, the perilla leaf mixing and stirring that will be cooked, with borneol
Grind as fine powder crosses 200 mesh dusting covers；
（2）Honey is refined into 110-115 DEG C of tender honey；
（3）The spice by weight 1 for fine powder will be ground：1 ratio adds mixing system in honey to stick together, then rubbing pill, per 6 grams of ball.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710121996.5A CN106822841A (en) | 2017-03-03 | 2017-03-03 | It is a kind of to treat medicine of asthma and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710121996.5A CN106822841A (en) | 2017-03-03 | 2017-03-03 | It is a kind of to treat medicine of asthma and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106822841A true CN106822841A (en) | 2017-06-13 |
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ID=59137163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710121996.5A Withdrawn CN106822841A (en) | 2017-03-03 | 2017-03-03 | It is a kind of to treat medicine of asthma and preparation method thereof |
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| Country | Link |
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| CN (1) | CN106822841A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1180546A (en) * | 1996-10-21 | 1998-05-06 | 王堇屹 | Medicament for treating asthma disease and its preparation method |
-
2017
- 2017-03-03 CN CN201710121996.5A patent/CN106822841A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1180546A (en) * | 1996-10-21 | 1998-05-06 | 王堇屹 | Medicament for treating asthma disease and its preparation method |
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Application publication date: 20170613 |