CN106819775A - A kind of additive of de- mycotoxin and its application - Google Patents
A kind of additive of de- mycotoxin and its application Download PDFInfo
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- CN106819775A CN106819775A CN201710066273.XA CN201710066273A CN106819775A CN 106819775 A CN106819775 A CN 106819775A CN 201710066273 A CN201710066273 A CN 201710066273A CN 106819775 A CN106819775 A CN 106819775A
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- additive
- mycotoxin
- bacillus subtilis
- humic acid
- yeast cell
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Abstract
The invention provides a kind of additive of de- mycotoxin, it is characterised in that：The additive is composed of the following components：Brewing yeast cell wall, yellow humic acid potassium, bacillus subtilis；Each component ratio is in every part of additive：Milligram/part of brewing yeast cell wall 200 500, milligram/part of yellow humic acid potassium 200 500 ,/part of bacillus subtilis 13 thousand ten thousand.Brewing yeast cell wall of the invention, yellow humic acid potassium, bacillus subtilis cooperates, play a role absorption zearalenone jointly, aflatoxins, the mycotoxins such as vomitoxin, absorption absorption pathogenic microorganism, reduce the harm of mycotoxin, improve the effect of growth of animal ability, bacillus subtilis is more beneficial for producing various digestive ferments and antibacterial peptide, with the balance of the absorption regulating intestinal canal flora that brewing yeast cell wall and yellow humic acid potassium synergy promote nutrition, the present invention can reach the effect that removing mycotoxin is completely eliminated, with safety, efficiently, the advantages of selectivity and few addition, also there is certain improvement to culture benefit, realize that animal husbandry economy benefit and social benefit are uniformly coordinated the purpose with sustainable development.
Description
Technical field
The present invention relates to breeding feed field, the additive of more particularly to a kind of de- mycotoxin and its application.
Background technology
The cereal crops such as corn are the main components of feed, and these cereal crops are the fungies such as Aspergillus flavus, sickle mycete
Good culture medium, the mycotoxins such as aflatoxins, zearalenone, vomitoxin can be produced.Aflatoxin is one
Plant the compound for having carcinogenicity and having acute toxicity；Zearalenone is a kind of estrogen-like matters, can cause the reproduction of pig
In organ function, the change of form；Vomitoxin endangers maximum for nonruminant, can cause oral area or throat inflammation, pain,
And slow body weight increase, diarrhoea, drowsiness or intestinal bleeding may be caused.Vomitoxin can also suppress immune system, make animal easy
Suffer from various communicable diseases.And industry there is no good solution.
The content of the invention
It is an object of the invention to solve to contain aflatoxins, zearalenone, vomitoxin in traditional breeding feed
Deng mycotoxin, harm animal health, the problem of influence growth of animal ability, there is provided one kind adds additive in feed, reaches
To reducing mycotoxin, reducing pathogenic microorganism, the harm for improving animal immunizing power, reducing mycotoxin, growth of animal is improved
The additive of a kind of de- mycotoxin of ability and its application.
The purpose of the present invention is reached by following technical measures：
A kind of additive of de- mycotoxin, it is characterised in that：The additive is composed of the following components：Saccharomyces cerevisiae is thin
Cell wall, yellow humic acid potassium, bacillus subtilis；Each component ratio is in every part of additive：Brewing yeast cell wall
200-500 milligrams/part, 200-500 milligrams/part of yellow humic acid potassium ,/part of bacillus subtilis 1-3 10,000,000.It is of the invention to add
Plus agent is used to remove the mycotoxin in feed, harm of the mycotoxin to growth of animal is eliminated.
Used as a kind of specific preferred scheme, each component ratio is in every part of additive：Brewing yeast cell wall 400
Milligram/part, milligram/part of yellow humic acid potassium 400 ,/part of bacillus subtilis 2,000 ten thousand.
The additive of de- mycotoxin disclosed by the invention is a kind of compound formulation, rotten by brewing yeast cell wall, yellow
POTASSIUM PHYTATE, bacillus subtilis cooperate, and collaboration plays absorption absorption pathogenic microorganism, reduces the harm of mycotoxin, carries
The effect of growth of animal ability high.Wherein brewing yeast cell wall：1. enhance immunity：β -1,3 glucans can strengthen macrophage
Cell, NK cells and functions of neutrophils, promote differentiation and the maturation of T, B lymphocyte, improve cellular immunity and body fluid is exempted from
The absorbing mycotoxin of epidemic disease function 2.：α -1 in yeast cell wall, 6 mannosans and β -1,3 glucans to zearalenone,
The mycotoxins such as aflatoxins, vomitoxin have very strong suction-operated, eliminate mycotoxin to growth of animal and immune
Suppress, improve growth of animal performance.3. pathogenic microorganism is adsorbed：α -1 in yeast cell wall, 6 mannosans and gut cell membrane
The glycoprotein structure on surface is similar to very much, specifically can be combined with sex pheromone, reduces sex pheromone and enterocyte
The chance of adhesion, prevents definite value of the pathogen in animal intestinal tract, improves animal health.
Yellow humic acid potassium is a kind of short carbon chain molecular structure material extracted from natural humic acid, and it has high capacity
Amount and physiologically active.Agricultural and Horticultural industry are generally used for, control of plant disease are applied to and are promoted constant and micro battalion
Material is supported for plant utilizes.It is applied to livestock-raising in the present invention, accelerates mycotoxin to decompose, improves the disease-resistant energy of livestock and poultry
Power, excites livestock and poultry microbiological activity；The nutrient absorption of feed is improved, promotes growth of animals or poultry.
Bacillus subtilis：Various digestive ferments and antibacterial peptide are produced, promote the balance of the absorption regulating intestinal canal flora of nutrition,
Improve resistance of the livestock and poultry to mycotoxin.
A kind of application of the additive of above-mentioned de- mycotoxin, it is characterised in that：The additive is raised added to cultivation
Application in material.By the additive added to can eliminate mycotoxin in breeding feed in breeding process, to adsorb cause of disease micro-
Biology, absorbing mycotoxin, maintain intestinal health, improve feed intake, improve immunity of organisms, promote growth of animal.
Used as a kind of preferred scheme, the addition of the additive is the 1 ‰ -3 ‰ of breeding feed total amount.
Experimental result show that the additive has good reduction in feed Mycotoxins in Feed content
Effect.
Experiment one：Absorption of the additive of the de- mycotoxin of the present invention to aflatoxin under simulated gastrointestinal tract pH value condition
Effect.The feed for taking manufacturer production is divided into 4 groups, one group without being blank, remaining is divided into repetition 1, repeat 2 and repeat 3
Totally three groups, additive of the invention is added according to the ratio of feed 3 ‰, 2 ‰, 1 ‰ respectively, feed is detected after being well mixed 24 hours
Middle aflatoxin content.
| Group | Aflatoxin content (ng/mL) in supernatant |
| Blank | 616.03±108.40 |
| Repeat 1 | 41.55±17.53 |
| Repeat 2 | 45.23±8.29 |
| Repeat 3 | 72.19±10.08 |
Experiment two：3 kinds of feeds of different manufacturers production are taken, is divided into repetition 1,2 repeated and totally three groups of repetition 3, according to feeding
Expect that 2 ‰ ratios add above-mentioned additive, Mycotoxins in Feed content, control are detected respectively within 6,12,24 hours after being well mixed
Group is the sample for being not added with additive of the present invention, and concrete outcome is shown in accompanying drawing 1.
By accompanying drawing 1 it can be seen that the mycotoxin in substantially can reducing feed after using additive of the invention contains
Amount.
By adopting the above-described technical solution, compared with prior art, it is an advantage of the invention that：
The additive of de- mycotoxin disclosed by the invention is a kind of compound formulation, has brewing yeast cell wall, yellow rotten
POTASSIUM PHYTATE, bacillus subtilis cooperate, and collaboration plays a role and adsorbs zearalenone, aflatoxins, vomitoxin etc.
Mycotoxin, absorption absorption pathogenic microorganism, reduces the harm of mycotoxin, improves the effect of growth of animal ability, withered grass bud
Spore bacillus is more beneficial for producing various digestive ferments and antibacterial peptide, promotees with brewing yeast cell wall and yellow humic acid potassium synergy
Enter the balance of the absorption regulating intestinal canal flora of nutrition, the present invention can reach the effect that removing mycotoxin is completely eliminated, with peace
Entirely, efficiently, the advantages of selectivity and addition are few, also there is certain improvement to culture benefit, animal husbandry economy benefit and society are realized
Meeting benefit is uniformly coordinated the purpose with sustainable development.
With reference to specific embodiment, the invention will be further described.
Brief description of the drawings
Fig. 1 is a kind of datagram of experiment two of the additive of de- mycotoxin of the present invention.
Specific embodiment
Embodiment 1：A kind of additive of de- mycotoxin, it is characterised in that：The additive is composed of the following components：Make
Brewer yeast cell membrane, yellow humic acid potassium, bacillus subtilis；Each component ratio is in every part of additive：Saccharomyces cerevisiae
Milligram/part of cell membrane 400, milligram/part of yellow humic acid potassium 400 ,/part of bacillus subtilis 2,000 ten thousand.By all groups of the invention
Mixing in proportion is divided to obtain final product the additive.
Embodiment 2：A kind of additive of de- mycotoxin, it is characterised in that：The additive is composed of the following components：Make
Brewer yeast cell membrane, yellow humic acid potassium, bacillus subtilis；Each component ratio is in every part of additive：Saccharomyces cerevisiae
Milligram/part of cell membrane 200, milligram/part of yellow humic acid potassium 500 ,/part of bacillus subtilis 3,000 ten thousand.By all groups of the invention
Mixing in proportion is divided to obtain final product the additive.
Embodiment 3：A kind of additive of de- mycotoxin, it is characterised in that：The additive is composed of the following components：Make
Brewer yeast cell membrane, yellow humic acid potassium, bacillus subtilis；Each component ratio is in every part of additive：Saccharomyces cerevisiae
Milligram/part of cell membrane 500, milligram/part of yellow humic acid potassium 200 ,/part of bacillus subtilis 1,000 ten thousand.By all groups of the invention
Mixing in proportion is divided to obtain final product the additive.
Embodiment 4：The additive of any de- mycotoxin in embodiment 1-3 is added in feed and is applied, it is described
The addition of additive is the 1 ‰ of breeding feed gross weight.Addition manner of the additive in feed is by above-mentioned addition
Agent is directly appended in breeding feed；Or premix, concentrate feed form are mixed and made into other feed addictives or feedstuff,
Feed to livestock and poultry.
Embodiment 5：The additive of any de- mycotoxin in embodiment 1-3 is added in feed and is applied, it is described
The addition of additive is the 2 ‰ of breeding feed gross weight.Addition manner of the additive in feed is by above-mentioned addition
Agent is directly appended in breeding feed；Or premix, concentrate feed form are mixed and made into other feed addictives or feedstuff,
Feed to livestock and poultry.
Embodiment 6：The additive of any de- mycotoxin in embodiment 1-3 is added in feed and is applied, it is described
The addition of additive is the 3 ‰ of breeding feed gross weight.Addition manner of the additive in feed is by above-mentioned addition
Agent is directly appended in breeding feed；Or premix, concentrate feed form are mixed and made into other feed addictives or feedstuff,
Feed to livestock and poultry.
Claims (4)
1. a kind of additive of de- mycotoxin, it is characterised in that：The additive is composed of the following components：Brewing yeast cell
Wall, yellow humic acid potassium, bacillus subtilis；Each component ratio is in every part of additive：Brewing yeast cell wall 200-
500 milligrams/part, 200-500 milligrams/part of yellow humic acid potassium ,/part of bacillus subtilis 1-3 10,000,000.
2. the additive of a kind of de- mycotoxin according to claim 1, it is characterised in that：It is each in every part of additive
Component ratio is：Milligram/part of brewing yeast cell wall 400, milligram/part of yellow humic acid potassium 400, bacillus subtilis 2,000 ten thousand
Individual/part.
3. the application of the additive of the de- mycotoxin described in a kind of claim 1 or 2, it is characterised in that：The additive exists
Added to the application in breeding feed.
4. the application of the additive of a kind of de- mycotoxin according to claim 3, it is characterised in that：The additive
Addition is the 1 ‰ -3 ‰ of breeding feed total amount.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201710066273.XA CN106819775A (en) | 2017-01-21 | 2017-01-21 | A kind of additive of de- mycotoxin and its application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201710066273.XA CN106819775A (en) | 2017-01-21 | 2017-01-21 | A kind of additive of de- mycotoxin and its application |
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Family
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| CN201710066273.XA Pending CN106819775A (en) | 2017-01-21 | 2017-01-21 | A kind of additive of de- mycotoxin and its application |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108813289A (en) * | 2018-06-01 | 2018-11-16 | 湖北华大瑞尔科技有限公司 | A kind of preparation and the preparation method and application thereof of high-performance bio degradation mycotoxin |
| CN108893416A (en) * | 2018-06-01 | 2018-11-27 | 河南广安生物科技股份有限公司 | It is a kind of degrade vomitoxin saccharomycete and its application |
| CN109287935A (en) * | 2018-09-26 | 2019-02-01 | 深圳市裕农科技股份有限公司 | A kind of mycotoxins in feed adsorbent and its application, feed |
| CN109363058A (en) * | 2017-09-29 | 2019-02-22 | 海南泓缘生物科技股份有限公司 | The biodegradation method of vomitoxin in a kind of pair of corn pulp |
| CN110393256A (en) * | 2019-08-07 | 2019-11-01 | 中鲨动物保健品（厦门）有限公司 | It is a kind of using brewing yeast cell wall as the mould inorganic agent of carrier |
| CN111607627A (en) * | 2020-05-12 | 2020-09-01 | 南京大方生物工程有限公司 | Fermentation process for producing antibacterial peptide bacillus subtilis and application of fermentation process in disease-resistant and yield-increasing of livestock and poultry |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109363058A (en) * | 2017-09-29 | 2019-02-22 | 海南泓缘生物科技股份有限公司 | The biodegradation method of vomitoxin in a kind of pair of corn pulp |
| CN108813289A (en) * | 2018-06-01 | 2018-11-16 | 湖北华大瑞尔科技有限公司 | A kind of preparation and the preparation method and application thereof of high-performance bio degradation mycotoxin |
| CN108893416A (en) * | 2018-06-01 | 2018-11-27 | 河南广安生物科技股份有限公司 | It is a kind of degrade vomitoxin saccharomycete and its application |
| CN108813289B (en) * | 2018-06-01 | 2022-05-17 | 湖北华大瑞尔科技有限公司 | Application method and preparation method of preparation for efficiently biodegrading mycotoxin |
| CN109287935A (en) * | 2018-09-26 | 2019-02-01 | 深圳市裕农科技股份有限公司 | A kind of mycotoxins in feed adsorbent and its application, feed |
| CN110393256A (en) * | 2019-08-07 | 2019-11-01 | 中鲨动物保健品（厦门）有限公司 | It is a kind of using brewing yeast cell wall as the mould inorganic agent of carrier |
| CN111607627A (en) * | 2020-05-12 | 2020-09-01 | 南京大方生物工程有限公司 | Fermentation process for producing antibacterial peptide bacillus subtilis and application of fermentation process in disease-resistant and yield-increasing of livestock and poultry |
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| TA01 | Transfer of patent application right |
Effective date of registration: 20181224 Address after: 261000 Weifang Economic Development Zone, Shandong Province, north of Yongkang Street, west of Youyou Road Applicant after: Weifang ZHONG CHUANG Bio Technology Co., Ltd. Address before: 261041 No. 170 Hangjiao Village Industrial Park, North Head of Rainbow Road, Weicheng District, Weifang City, Shandong Province Applicant before: Weifang China Pharmaceutical Co., Ltd. |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170613 |
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