CN106806781A - A kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof - Google Patents

A kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof Download PDF

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CN106806781A
CN106806781A CN201510839389.3A CN201510839389A CN106806781A CN 106806781 A CN106806781 A CN 106806781A CN 201510839389 A CN201510839389 A CN 201510839389A CN 106806781 A CN106806781 A CN 106806781A
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asiatic plantain
chinese medical
reducing fever
causing diuresis
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陈喜军
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Heilongjiang Zhongsheng Biological Engineering Co Ltd
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Heilongjiang Zhongsheng Biological Engineering Co Ltd
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Abstract

A kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof, is made up of Chinese medical extract, filler, disintegrant, adhesive, lubricant, flavouring, glidant, and the preferred weight number of raw material is in described Chinese medical extract:Asiatic plantain 30-45 parts, roud cardamon seed 15-25 parts, Canton love-pea vine 15-25 parts, thick grass 7-14 parts, 7-14 parts, black beard and hair 7-14 parts, desmodium triquetrum 3-6 parts, Fructus Caryophylli 3-6 parts, fructus polygoni orientalis 3-6 parts, lily 3-6 parts of the lotus base of a fruit.Its preparation method is mainly comprised the following steps:(1)Prepare Chinese medical extract:A, pretreatment of raw material;B, prepare mixed extract;C, filtering, concentration, drying;(2)Prepare Asiatic plantain reducing fever and causing diuresis piece:A, mixing;B, drying;C, mixing.A kind of Asiatic plantain reducing fever and causing diuresis piece of the invention, long-term taking has reducing fever and causing diuresis, cool blood, effect of removing toxic substances.

Description

A kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof
Technical field
The present invention relates to a kind of health products, particularly a kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof.
Background technology
Blood-head, refers to that during heat enters blood, blood accelerates and the pathological state of exception.Blood-head also can cause blood-head more caused by heat symptoms caused by an exopathgen enter blood due to feelings will pent-up, fire syndrome caused by overreaction of the five emotion. Also known as blood system is warm.I.e. blood system has heat.Symptoms include hematemesis, cough cough up, drown blood, fever in the afternoon, woman's menses, stringy and rapid pulse, method worked as cool blood in advance.One of fever in children card type.
Internal organs are intimately flourishing, the syndrome that the urgent blood system of heat is showed.Clinical to be generated heat with abnormal circulation of blood, notably then coma etc. is the card of main performance.More because bothering, throw off restraint the factors such as hot, the angry impariment of the liver of food, sexual strain and cause.The operation of blood, You Qichang roads, internal organs are burning hot, interior urgent blood system, and channels is injured , blood do not follow Chang Dao and excessive.Therefore blood-heat syndrome is with bleeding and thermal image as principal character.Lung network hinders then hemoptysis, and stomach network wound is then spitted blood, and bladder network hinders then hematuria, and large intestine network wound is then had blood in stool;The visible nosebleed epistaxis of bleeding of skin, bleeding from the gum, tongue nosebleed, flesh nosebleed etc..Woman in menstrual period early stage, is also excessively the performance of blood-head through amount.With seeing vexed, flushing, thirst and liking cold drink, tongue is red, and wiry and frequent pulse effectively waits thermal image witness.Blood system is intimately flourishing, has internal injury diseases caused by external factors not, and the blood-heat syndrome seen in miscellaneous diseases caused by endogenous pathogens discussed above, exterior syndrome heat invading xuefen is shown in analysing, differentiating and judging the development of a disease by studying the four conditions of the human body.Blood-heat syndrome controls suitable clearing heat and cooling blood, side such as huanglian jiedu decoction, xijiao Dihuang Tang.
At present, the medicine or health products of in the market reducing fever and causing diuresis have a lot, but the effect of most drug is not fine, and the side effect of most drug is more, health can be damaged, though health products have certain effect, its price is high, therefore, in the market be badly in need of it is a kind of it is pure natural, have no toxic side effect Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof.
The content of the invention
It is an object of the invention to provide a kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof, long-term taking have reducing fever and causing diuresis, Cool blood, removing toxic substances Effect.
The purpose of the present invention is achieved through the following technical solutions:
A kind of Asiatic plantain reducing fever and causing diuresis piece, it is made up of Chinese medical extract, filler, disintegrant, adhesive, lubricant, flavouring, glidant, by weight percentage, Chinese medical extract 20-60%, filler 20-50%, disintegrant 10-40%, adhesive 1-20%, lubricant 1-5%, flavouring 1-5%, glidant 1-5%;By weight, Chinese medical extract 20-60 parts, filler 20-50 parts, disintegrant 10-40 parts, adhesive 1-20 parts, lubricant 1-5 parts, flavouring 1-5 parts, glidant 1-5 parts.
Described a kind of Asiatic plantain reducing fever and causing diuresis piece, by optimum weight number, 40 parts of Chinese medical extract, 30 parts of filler, 15 parts of disintegrant, 5 parts of adhesive, 4 parts of lubricant, 3 parts of flavouring, 3 parts of glidant.
The preferred weight number of raw material is in described Chinese medical extract:Asiatic plantain 30-45 parts, roud cardamon seed 15-25 parts, Canton love-pea vine 15-25 parts, thick grass 7-14 parts, 7-14 parts, black beard and hair 7-14 parts, desmodium triquetrum 3-6 parts, Fructus Caryophylli 3-6 parts, fructus polygoni orientalis 3-6 parts, lily 3-6 parts of the lotus base of a fruit.
The optimum weight number of raw material is in described Chinese medical extract:40 parts of Asiatic plantain, 20 parts of roud cardamon seed, 18 parts of Canton love-pea vine, 14 parts of thick grass, 10 parts of the lotus base of a fruit, 7 parts of black beard and hair, 6 parts of desmodium triquetrum, 5 parts of Fructus Caryophylli, 4 parts of fructus polygoni orientalis, 3 parts of lily.
Described filler is the mixing of one or more in microcrystalline cellulose, starch, lactose, dextrin, sucrose;Described disintegrant is low-substituted hydroxypropyl cellulose;Described adhesive is starch slurry or PVP k30 or Hydroxypropyl methylcellulose;Described lubricant is one or two the mixing in magnesium stearate, lauryl sodium sulfate;Described flavouring is the mixing of one or more in aspartame, Steviosin, citric acid, essence;Described glidant is one or two the mixing in silica, talcum powder.
Described a kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof, it is characterised in that:Its preparation method is mainly comprised the following steps:
(1)Prepare Chinese medical extract:
a , pretreatment of raw material:By weight, Asiatic plantain, roud cardamon seed, Canton love-pea vine, thick grass, the lotus base of a fruit, black beard and hair, desmodium triquetrum, Fructus Caryophylli, fructus polygoni orientalis, lily are chosen, is cleaned and removal of impurities, it is standby;
b , prepare mixed extract:Asiatic plantain, roud cardamon seed, Canton love-pea vine, thick grass, the lotus base of a fruit, black beard and hair, desmodium triquetrum, Fructus Caryophylli, fructus polygoni orientalis, lily are well mixed, are then boiled three times with decocting, 14 times of water is added for the first time, moderate heat is decocted 2-3 hours, filtering, extracts filtrate, second plus 12 times of water, moderate heat is decocted 1.5-2 hours, filtering, filtrate is extracted, the water big fire that third time Jia 10 is decocted 0.5 hour, filtering, extract filtrate, merge three filtrates, obtain mixed extract, it is standby;
c , filtering, concentration, dry:Mixed extract is taken, is filtered, be then concentrated under reduced pressure, when being concentrated into 60 DEG C, relative density is the clear cream of 1.22-1.3, is subsequently placed in spray dryer and is spray-dried, and is placed in after drying in pulverizer and crushed, and crosses 60 mesh sieves, obtains Chinese medical extract;
(2)Prepare Asiatic plantain reducing fever and causing diuresis piece:
a , mixing:By weight, Chinese medical extract, filler, disintegrant are taken to be well mixed, is subsequently placed in In wet granulator, adhesive is put into feed tank, opens machine, adjusting parameter, while opening shearing fly cutter, 2-5 minutes, discharging used oscillating granulator, mistake 16 Mesh nylon screen is pelletized, and wet granular is obtained
b , dry:Wet granular is placed in dryer and is dried, ultraviolet disinfection is used after drying, obtain whole grain;
c , mixing:Whole grain, lubricant, flavouring, glidant are mixed, is placed in three-dimensional motion mixer and is mixed 15-25 minutes, then using rotary pelleting machine compressing tablet, a kind of Asiatic plantain reducing fever and causing diuresis piece is obtained.
In medicine: Asiatic plantain, reducing fever and causing diuresis, cool blood, removing toxic substances;Cure mainly bladder heat stagnation, difficult urination, stranguria with turbid discharge under band, summer-heat and damp rush down dysentery, bleeding from five sense organs or subcutaneous tissue, hematuria, the hot hot eyes of liver, abscess of throat, carbuncle sore tumefacting virus;Roud cardamon seed, regulating the flow of QI to ease the stomach, dry cold-dampness, relieving alcoholism;Treat for stomachache the diseases such as abdominal distension, gas gastric disorder causing nausea;Canton love-pea vine, clearing heat and promoting diuresis, blood stasis removing analgesic;Main icteric hepatitis, stomachache, treating rheumatic ostealgia, bruise stasis caused pain, thick grass, wind-dispelling, detumescence;Control head wind, carbuncle swells, skin paralysis, scrofula, acute mastitis, larynx numbness, hernia lump in the abdomen, tinea scabies, the favus of the scalp, wind carious pain;The lotus base of a fruit, Clear heat dehumidifying, arresting bleeding and miscarriage prevention, tonifying middle-Jiao and Qi;It is antiabortive with stomach, stop-band of stopping blooding;Can be used for fetal irritability and the inferior disease of uterine bleeding band;There is the work(of liter act, the diseases such as the sagging rush down prolapse of the anus for a long time of clear gas are can be used for again; Black beard and hair ;Cure mainly:Light-headedness;Soreness and weakness of waist and knees;Seminal emission;Tinnitus;Poliosis, osteopyrexia and fever;Desmodium triquetrum, heat-clearing, dampness removing disappears stagnant, desinsection;Cure cold, pharyngalgia, tuberculosis hemoptysis, enteritis, dysentery, jaundice, rheumatic arthritis, hookworm disease, the vomiting of pregnancy, infantile malnutrition, sore scabies;Fructus Caryophylli, middle benefit gas, cold dispelling;Control sudden and violent heart pain, stomach cold is vomitted inverse, air-cooled dentalgia, pingival atrophy, halitosis, married woman is sombre, children's hernia;Fructus polygoni orientalis, heat-clearing, softening hard masses;The broken product of dispersing blood stasis, invigorating spleen to remove dampness;Flank disease product is controlled, ascites has a stomach-ache, deficiency of food abdominal distension, pinkeye, sore swells, scrofula
Beneficial effects of the present invention:A kind of Asiatic plantain reducing fever and causing diuresis piece of the invention, based on secret prescription handed down in the family from generation to generation, selected Asiatic plantain, roud cardamon seed, Canton love-pea vine, thick grass, the lotus base of a fruit, black beard and hair, desmodium triquetrum, Fructus Caryophylli, fructus polygoni orientalis, lily, etc. raw material be combined, so that the drug effect of various medicines produces synergy, so as to reach effect, long-term taking has reducing fever and causing diuresis, cool blood, effect of removing toxic substances.
Through two groups of clinical verifications, one of which takes the present invention to the present invention for treatment group, and the present invention is taken daily once, and 7 days is a course for the treatment of, and another group of control group is taken Reducing fever and causing diuresis capsule , it is within 7 days a course for the treatment of daily using once, per group selection outpatient 52, wherein man 32, female 20, max age 75 years old, minimal ages 35 years old, clinical manifestation is Abdominal fullness and distention, Difficult urination Stranguria with turbid discharge under band , table one is to take the contrasting data after a course for the treatment of:
Table 1 takes front and rear two groups of courses for the treatment of and compares (unit:People)
There were significant differences for treatment group and control group, it will thus be seen that present invention application clinically has significant curative effect.
Technological advantage of the invention is:1st, raw material science is selected, production technology is advanced;2nd, in product without spices and preservative, raw material local flavor in itself and nutrition are kept, is easily absorbed by the body;3rd, raw material sources are extensive, plus process line is short, the manufacture of product easy processing.
Specific embodiment
Embodiment 1
A kind of Asiatic plantain reducing fever and causing diuresis piece, it is made up of Chinese medical extract, filler, disintegrant, adhesive, lubricant, flavouring, glidant, by weight percentage, Chinese medical extract 20-60%, filler 20-50%, disintegrant 10-40%, adhesive 1-20%, lubricant 1-5%, flavouring 1-5%, glidant 1-5%;By weight, Chinese medical extract 20-60 parts, filler 20-50 parts, disintegrant 10-40 parts, adhesive 1-20 parts, lubricant 1-5 parts, flavouring 1-5 parts, glidant 1-5 parts.
Described a kind of Asiatic plantain reducing fever and causing diuresis piece, by optimum weight number, 40 parts of Chinese medical extract, 30 parts of filler, 15 parts of disintegrant, 5 parts of adhesive, 4 parts of lubricant, 3 parts of flavouring, 3 parts of glidant.
The preferred weight number of raw material is in described Chinese medical extract:Asiatic plantain 30-45 parts, roud cardamon seed 15-25 parts, Canton love-pea vine 15-25 parts, thick grass 7-14 parts, 7-14 parts, black beard and hair 7-14 parts, desmodium triquetrum 3-6 parts, Fructus Caryophylli 3-6 parts, fructus polygoni orientalis 3-6 parts, lily 3-6 parts of the lotus base of a fruit.
The optimum weight number of raw material is in described Chinese medical extract:40 parts of Asiatic plantain, 20 parts of roud cardamon seed, 18 parts of Canton love-pea vine, 14 parts of thick grass, 10 parts of the lotus base of a fruit, 7 parts of black beard and hair, 6 parts of desmodium triquetrum, 5 parts of Fructus Caryophylli, 4 parts of fructus polygoni orientalis, 3 parts of lily.
Described filler is the mixing of one or more in microcrystalline cellulose, starch, lactose, dextrin, sucrose;Described disintegrant is low-substituted hydroxypropyl cellulose;Described adhesive is starch slurry or PVP k30 or Hydroxypropyl methylcellulose;Described lubricant is one or two the mixing in magnesium stearate, lauryl sodium sulfate;Described flavouring is the mixing of one or more in aspartame, Steviosin, citric acid, essence;Described glidant is one or two the mixing in silica, talcum powder.
A kind of described Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof, its preparation method is mainly comprised the following steps:
(1)Prepare Chinese medical extract:
a , pretreatment of raw material:By weight, Asiatic plantain, roud cardamon seed, Canton love-pea vine, thick grass, the lotus base of a fruit, black beard and hair, desmodium triquetrum, Fructus Caryophylli, fructus polygoni orientalis, lily are chosen, is cleaned and removal of impurities, it is standby;
b , prepare mixed extract:Asiatic plantain, roud cardamon seed, Canton love-pea vine, thick grass, the lotus base of a fruit, black beard and hair, desmodium triquetrum, Fructus Caryophylli, fructus polygoni orientalis, lily are well mixed, are then boiled three times with decocting, 14 times of water is added for the first time, moderate heat is decocted 2-3 hours, filtering, extracts filtrate, second plus 12 times of water, moderate heat is decocted 1.5-2 hours, filtering, filtrate is extracted, the water big fire that third time Jia 10 is decocted 0.5 hour, filtering, extract filtrate, merge three filtrates, obtain mixed extract, it is standby;
c , filtering, concentration, dry:Mixed extract is taken, is filtered, be then concentrated under reduced pressure, when being concentrated into 60 DEG C, relative density is the clear cream of 1.22-1.3, is subsequently placed in spray dryer and is spray-dried, and is placed in after drying in pulverizer and crushed, and crosses 60 mesh sieves, obtains Chinese medical extract;
(2)Prepare Asiatic plantain reducing fever and causing diuresis piece:
a , mixing:By weight, Chinese medical extract, filler, disintegrant are taken to be well mixed, is subsequently placed in In wet granulator, adhesive is put into feed tank, opens machine, adjusting parameter, while opening shearing fly cutter, 2-5 minutes, discharging used oscillating granulator, mistake 16 Mesh nylon screen is pelletized, and wet granular is obtained
b , dry:Wet granular is placed in dryer and is dried, ultraviolet disinfection is used after drying, obtain whole grain;
c , mixing:Whole grain, lubricant, flavouring, glidant are mixed, is placed in three-dimensional motion mixer and is mixed 15-25 minutes, then using rotary pelleting machine compressing tablet, a kind of Asiatic plantain reducing fever and causing diuresis piece is obtained.

Claims (6)

1. a kind of Asiatic plantain reducing fever and causing diuresis piece, it is characterised in that:It is made up of Chinese medical extract, filler, disintegrant, adhesive, lubricant, flavouring, glidant, by weight percentage, Chinese medical extract 20-60%, filler 20-50%, disintegrant 10-40%, adhesive 1-20%, lubricant 1-5%, flavouring 1-5%, glidant 1-5%;By weight, Chinese medical extract 20-60 parts, filler 20-50 parts, disintegrant 10-40 parts, adhesive 1-20 parts, lubricant 1-5 parts, flavouring 1-5 parts, glidant 1-5 parts.
2. a kind of Asiatic plantain reducing fever and causing diuresis piece according to claim 1, it is characterised in that:By optimum weight number, 40 parts of Chinese medical extract, 30 parts of filler, 15 parts of disintegrant, 5 parts of adhesive, 4 parts of lubricant, 3 parts of flavouring, 3 parts of glidant.
3. a kind of Asiatic plantain reducing fever and causing diuresis piece according to claim 1, it is characterised in that:The preferred weight number of raw material is in described Chinese medical extract:Asiatic plantain 30-45 parts, roud cardamon seed 15-25 parts, Canton love-pea vine 15-25 parts, thick grass 7-14 parts, 7-14 parts, black beard and hair 7-14 parts, desmodium triquetrum 3-6 parts, Fructus Caryophylli 3-6 parts, fructus polygoni orientalis 3-6 parts, lily 3-6 parts of the lotus base of a fruit.
4. a kind of Asiatic plantain reducing fever and causing diuresis piece according to claim 1, it is characterised in that:The optimum weight number of raw material is in described Chinese medical extract:40 parts of Asiatic plantain, 20 parts of roud cardamon seed, 18 parts of Canton love-pea vine, 14 parts of thick grass, 10 parts of the lotus base of a fruit, 7 parts of black beard and hair, 6 parts of desmodium triquetrum, 5 parts of Fructus Caryophylli, 4 parts of fructus polygoni orientalis, 3 parts of lily.
5. a kind of Asiatic plantain reducing fever and causing diuresis piece according to claim 1, it is characterised in that:Described filler is the mixing of one or more in microcrystalline cellulose, starch, lactose, dextrin, sucrose;Described disintegrant is low-substituted hydroxypropyl cellulose;Described adhesive is starch slurry or PVP k30 or Hydroxypropyl methylcellulose;Described lubricant is one or two the mixing in magnesium stearate, lauryl sodium sulfate;Described flavouring is the mixing of one or more in aspartame, Steviosin, citric acid, essence;Described glidant is one or two the mixing in silica, talcum powder.
6. a kind of Asiatic plantain reducing fever and causing diuresis piece according to claim 1-5 and preparation method thereof, it is characterised in that:Its preparation method is mainly comprised the following steps:
(1)Prepare Chinese medical extract:
A, pretreatment of raw material:By weight, Asiatic plantain, roud cardamon seed, Canton love-pea vine, thick grass, the lotus base of a fruit, black beard and hair, desmodium triquetrum, Fructus Caryophylli, fructus polygoni orientalis, lily are chosen, is cleaned and removal of impurities, it is standby;
B, prepare mixed extract:Asiatic plantain, roud cardamon seed, Canton love-pea vine, thick grass, the lotus base of a fruit, black beard and hair, desmodium triquetrum, Fructus Caryophylli, fructus polygoni orientalis, lily are well mixed, are then boiled three times with decocting, 14 times of water is added for the first time, moderate heat is decocted 2-3 hours, filtering, extracts filtrate, second plus 12 times of water, moderate heat is decocted 1.5-2 hours, filtering, filtrate is extracted, the water big fire that third time Jia 10 is decocted 0.5 hour, filtering, extract filtrate, merge three filtrates, obtain mixed extract, it is standby;
C, filtering, concentration, drying:Mixed extract is taken, is filtered, be then concentrated under reduced pressure, when being concentrated into 60 DEG C, relative density is the clear cream of 1.22-1.3, is subsequently placed in spray dryer and is spray-dried, and is placed in after drying in pulverizer and crushed, and crosses 60 mesh sieves, obtains Chinese medical extract;
(2)Prepare Asiatic plantain reducing fever and causing diuresis piece:
A, mixing:By weight; take Chinese medical extract, filler, disintegrant to be well mixed, be subsequently placed in wet granulator, adhesive is put into feed tank; open machine; adjusting parameter, while opening shearing fly cutter, 2-5 minutes; discharging; using oscillating granulator, the granulation of 16 mesh nylon screens is crossed, wet granular is obtained;
B, drying:Wet granular is placed in dryer and is dried, ultraviolet disinfection is used after drying, obtain whole grain;
C, mixing:Whole grain, lubricant, flavouring, glidant are mixed, is placed in three-dimensional motion mixer and is mixed 15-25 minutes, then using rotary pelleting machine compressing tablet, a kind of Asiatic plantain reducing fever and causing diuresis piece is obtained.
CN201510839389.3A 2015-11-27 2015-11-27 A kind of Asiatic plantain reducing fever and causing diuresis piece and preparation method thereof Pending CN106806781A (en)

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