CN106754305A - Parallel multi-joint fermentation tank - Google Patents
Parallel multi-joint fermentation tank Download PDFInfo
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- CN106754305A CN106754305A CN201611029332.8A CN201611029332A CN106754305A CN 106754305 A CN106754305 A CN 106754305A CN 201611029332 A CN201611029332 A CN 201611029332A CN 106754305 A CN106754305 A CN 106754305A
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- Prior art keywords
- fermentation tank
- joint
- fermentation
- feed supplement
- flange
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- 238000000855 fermentation Methods 0.000 title claims abstract description 62
- 230000004151 fermentation Effects 0.000 title claims abstract description 62
- 239000006052 feed supplement Substances 0.000 claims abstract description 34
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 16
- 230000007246 mechanism Effects 0.000 claims abstract description 10
- 230000008878 coupling Effects 0.000 claims description 17
- 238000010168 coupling process Methods 0.000 claims description 17
- 238000005859 coupling reaction Methods 0.000 claims description 17
- 238000000926 separation method Methods 0.000 claims description 16
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 15
- 229910052782 aluminium Inorganic materials 0.000 claims description 15
- 239000004411 aluminium Substances 0.000 claims description 15
- 238000012546 transfer Methods 0.000 claims description 15
- 238000009833 condensation Methods 0.000 claims description 9
- 230000005494 condensation Effects 0.000 claims description 9
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims description 9
- 238000007789 sealing Methods 0.000 claims description 7
- 239000004065 semiconductor Substances 0.000 claims description 7
- 239000000853 adhesive Substances 0.000 claims description 3
- 230000001070 adhesive effect Effects 0.000 claims description 3
- 238000003860 storage Methods 0.000 claims description 2
- 229920002981 polyvinylidene fluoride Polymers 0.000 claims 1
- 238000011169 microbiological contamination Methods 0.000 abstract description 6
- 230000001954 sterilising effect Effects 0.000 abstract description 4
- 239000007789 gas Substances 0.000 description 15
- 230000000694 effects Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 230000004907 flux Effects 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000010364 biochemical engineering Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 3
- 239000004810 polytetrafluoroethylene Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- -1 polytetrafluoroethylene Polymers 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/58—Reaction vessels connected in series or in parallel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
- C12M37/04—Seals
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
- C12M41/22—Heat exchange systems, e.g. heat jackets or outer envelopes in contact with the bioreactor walls
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/44—Means for regulation, monitoring, measurement or control, e.g. flow regulation of volume or liquid level
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Sustainable Development (AREA)
- Analytical Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention provides parallel multi-joint fermentation tank, it can be solved, and existing parallel multi-joint fermentation tank microbiological contamination risk is big, the dismounting before and after sterilizing, install relatively complicated, difficult technical problem.Its technical scheme is such, and it includes rack and fermentation tank, it is characterised in that：Rack includes machine cabinet body, machine cabinet body top is provided with feed supplement bottle holder frame, sidepiece and is provided with fermentation canister bracket and is provided with accommodating cavity positioned at feed supplement bottle holder frame lower section, peristaltic pump is provided with accommodating cavity, the bottom wall of feed supplement bottle holder frame is provided with the through hole connected with peristaltic pump accommodating cavity, the feed supplement pipe of feed supplement bottle connection connects the input of peristaltic pump after through hole, and fermentation canister bracket is provided with some fermentation tanks；Fermentation tank includes tank body and rabbling mechanism；The upper end open of tank body is encapsulated by end socket；Rabbling mechanism includes motor, electric machine stand, bearing block and agitating shaft.
Description
Technical field
The present invention relates to biotech equipment field, more particularly to parallel multi-joint fermentation tank.
Background technology
Fermentation tank, is one kind of bioreactor.And parallel multi-joint fermentation tank such as can be right except the effect of common fermentation tank
Outside cell, microorganism or small plant are cultivated, the high flux screening of cell and strain, protein expression and dynamic are applied also for
The fields such as mechanics study, enzymatic activity test, fermentation technology optimization, synthetic biology research, belong to the one of high flux experimental technique
Part.Specifically can help to realize the high flux and high efficiency of bioprocess engineering research, accelerate to realize from DNA to product
Time history.Also so that early stage bioprocess engineering developme, so that it may which discovery feature strain or genetically engineered cell are in life
The dynamic physiological characteristic parameter such as metabolism, growth, production in thing reactor, it is determined that can production optimum cell clone, it is bright
Really the key scientific problems in the bioprocess engineering such as key process parameters related to quality, realize the newest biological mistake of QbD
Journey research theory etc..In recent ten years, the ripe development of high flux experimental technique, has promoted life science in every field
Efficiency is significantly improved.The parallel multi-joint fermentation tank overwhelming majority that can be at this stage needs import, and it is the country to trace it to its cause
The equipment microbiological contamination risk of production is big, sterilizing is front and rear dismounting, the relatively complicated, difficulty of installation.
The content of the invention
Regarding to the issue above, the invention provides parallel multi-joint fermentation tank, it can solve existing parallel multi-joint fermentation tank
Microbiological contamination risk is big, the dismounting before and after sterilizing, install relatively complicated, difficult technical problem.
Its technical scheme is such, and it includes rack and fermentation tank, it is characterised in that：
The rack include machine cabinet body, the machine cabinet body top be provided with feed supplement bottle holder frame, sidepiece be provided with fermentation canister bracket, with
And accommodating cavity is provided with positioned at feed supplement bottle holder frame lower section, peristaltic pump is provided with the accommodating cavity, on the bottom wall of the feed supplement bottle holder frame
The through hole connected with the peristaltic pump accommodating cavity is provided with, the feed supplement pipe of feed supplement bottle connection connects peristaltic pump after the through hole
Input, the fermentation canister bracket is provided with some fermentation tanks；
The fermentation tank includes tank body and rabbling mechanism；
The upper end open of the tank body is encapsulated by end socket；
The rabbling mechanism includes motor, electric machine stand, bearing block and agitating shaft；The motor be fixed on electric machine stand seat it is upper,
Motor shaft is stretched into the support cavity of electric machine stand, and the motor shaft is located on the position in support cavity and is connected with motor shaft connection
Female connector, is connected with outer magnetic group on the motor shaft coupling sleeve, the bearing block is fixed on end socket, and the agitating shaft is supported in axle
Bearing, its upper end are connected with interior magnetic group, and the motor shaft coupling sleeve is sheathed in the interior magnetic group, the motor shaft coupling sleeve
Separation sleeve is provided between the interior magnetic group, the separation sleeve is tightly connected with the electric machine stand, bearing block respectively.
Further, the end socket includes blind flange and flange circle, and the upper end of the tank body is provided with what is extended laterally
Flange, the blind flange is installed on the flange upside end face and covers the upper end open of tank body, and the flange snare is located at institute
State tank body and be resisted against the downside end face of flange, the blind flange and the flange circle are connected by bolt, nut assembly；
The blind flange downside is provided with the sealing ring with the lip fits.
Further, the tail gas condensing pipe connected with the tank body, the tail gas condensing pipe are connected with the blind flange
Condensation is provided with, the condensation includes the fixed aluminium block of heat transfer, semiconductor chilling plate, fin and radiator fan, institute
State the groove that the fixed aluminium block of heat transfer is provided with magnet and Longitudinal extending, the two fixed aluminium blocks of heat transfer by the mutual adhesive of magnet and
By the grooves hold tail gas condensing pipe being oppositely arranged, the semiconductor chilling plate, fin are in turn secured to one of biography
On the end face opposite with groove of heat fixation aluminium block, the fin is provided with radiator fan.
Further, the tail gas condensing pipe includes guiding tube, and the upper end of the guiding tube press-fits fixation by swivel nut
Have joint, the swivel nut is threadedly coupled with guiding tube, the bottom of the joint stretch into the guiding tube and with the guiding
Pipe interval setting, the bottom of the joint is threaded with flow-disturbing axle, its tube wall and is provided with and leading that the guiding tube is connected
Discharge orifice, the flow-disturbing axle is provided with the flow-disturbing flange for radially extending.
Further, the separation sleeve is provided with cover body convex shoulder, and the bearing block is provided with pedestal convex shoulder, the motor machine
The bottom of seat is threadedly coupled with the upper end of separation sleeve and is resisted against the upper surface of the cover body convex shoulder, the bearing block
Upper end is threadedly coupled with the bottom of separation sleeve, its pedestal convex shoulder is resisted against on the lower surface of cover body convex shoulder, and the cover body is convex
Sealing ring is embedded between shoulder and the pedestal convex shoulder.
Further, the fermentation canister bracket is provided with U-type groove, case, and the case is rotated with the U-lag side and connected
Connect and can be fastened on the case；
Further, containing cavities are additionally provided with the fermentation canister bracket, receiver both sides pass through link assembly and the containing cavities
Two side connection and can house with the containing cavities.
Further, form is offered on the front side wall of the feed supplement bottle holder frame.
Parallel multi-joint fermentation tank of the invention, machine cabinet body top be provided with feed supplement bottle holder frame, positioned at feed supplement bottle holder frame lower section
Accommodating cavity is provided with, peristaltic pump is provided with accommodating cavity, the bottom wall of feed supplement bottle holder frame is provided with the through hole connected with peristaltic pump accommodating cavity,
The feed supplement pipe of feed supplement bottle connection connects the input of peristaltic pump after the through hole, by 75% ethanol that is set in some feed supplements bottle,
The parallel tank bodies and each pipeline for practicing fermentation tank are carried out online sterilization of liquids, so that nothing by 2 mol/L NaOH and sterilized water more
Fermentation tank and each pipeline need to be dismantled, disinfecting action is more convenient；Motor shaft is located on the position in support cavity and is connected with electricity
Arbor coupling sleeve, is connected with outer magnetic group on motor shaft coupling sleeve, the upper end of agitating shaft is connected with interior magnetic group, motor shaft coupling sleeve
It is sheathed in interior magnetic group, outer magnetic group forms closed magnetic circuit with interior magnetic group, electric machine rotational axis drive motor axle coupling sleeve is rotated, motor
Axle coupling sleeve drives agitating shaft to rotate by magneticaction, makes agitating shaft and motor shaft synchronous axial system, motor shaft coupling sleeve with it is interior
Separation sleeve is provided between magnetic group, separation sleeve is tightly connected with electric machine stand, bearing block respectively, bearing cap and bearing block inner space
It is isolated from the outside, reduces microbiological contamination probability.
Brief description of the drawings
Fig. 1 is structural representation of the invention.
Fig. 2 is the structural representation of fermentation tank of the invention.
Fig. 3 is the main structure diagram of the partial cutaway of fermentation tank of the invention.
Fig. 4 is the overlooking the structure diagram of fermentation tank of the invention.
Fig. 5 is the structural representation of rabbling mechanism of the invention.
Fig. 6 is the attachment structure schematic diagram of electric machine stand of the invention, cage, bearing block.
Fig. 7 is the sectional view after tail gas condensing pipe of the invention is assembled with condensation.
Fig. 8 is the decomposition texture schematic diagram of tail gas condensing pipe of the invention and condensation.
Fig. 9 is the structural representation at visual angle of rack of the invention.
Figure 10 is the structural representation at another visual angle of rack of the invention.
Reference：10- fermentation tanks；11- rabbling mechanisms；111- motors；1111- motor shafts；112- electric machine stands；113-
Motor shaft coupling sleeve；The outer magnetic groups of 1131-；Magnetic group in 114-；115- cages；1151- cover body convex shoulders；116- bearing blocks；1161-
Pedestal convex shoulder；117- bearings；118- agitating shafts；12- end sockets；121- blind flanges；122- flange circles；123- feed supplement joints；124-
Air tube assembly；125- tail gas condensing pipes；1251- guiding tubes；1252- joints；1253- swivel nuts；1254- flow-disturbing axles；1255- is disturbed
Stream flange；126- temperature sleeves；127- level electrode components；128- bump joints；129- probe tubes；13- tank bodies；14- is condensed
Component；141- fin；The fixed aluminium block of 142- heat transfers；1421- grooves；143- semiconductor chilling plates；144- radiator fans；
The fixed aluminium block of 1422- heat transfers；20- racks；21- machine cabinet bodies；211- cases；22- fermentation canister brackets；221- temperature control chucks；
222-U shape grooves；223- cases；224- receivers；2241- dividing plates；225- link assemblies；226- containing cavities；23- feed supplement bottle holder
Frame；231- through holes；232- forms.
Specific embodiment
As shown in Fig. 1 ~ Figure 10, parallel multi-joint fermentation tank, it includes rack 20 and fermentation tank 10,
Rack 20 include machine cabinet body 21, the top of machine cabinet body 21 be provided with feed supplement bottle holder frame 23, sidepiece be provided with fermentation canister bracket 22,
And accommodating cavity is provided with positioned at feed supplement bottle holder frame lower section, and peristaltic pump is provided with accommodating cavity, opened up on the front side wall of feed supplement bottle holder frame
There is form 232, bottom wall to be provided with the through hole 231 connected with peristaltic pump accommodating cavity, the feed supplement pipe of feed supplement bottle connection is after through hole
The input of peristaltic pump is connected, fermentation canister bracket 22 is provided with mounting hole, and fermentation tank is arranged in mounting hole and is arranged with temperature control
Chuck 221；
Fermentation tank includes tank body 13 and rabbling mechanism 11；
The upper end open of tank body 13 is encapsulated by end socket 12, specifically, end socket 12 includes blind flange 121 and flange circle 122, tank body
13 are provided with the flange for extending laterally, and flange upside is provided with the blind flange 121 for covering the upper end open of tank body 13, and flange underside is provided with
The flange circle 122 of tank body 13 is sheathed on, blind flange 121 and flange circle 122 are connected by bolt, nut assembly；Blind flange
121 downsides are provided with the sealing ring with lip fits；
Rabbling mechanism 11 includes motor, electric machine stand 112, bearing block 116 and agitating shaft 118；Motor is fixed on electric machine stand 112
On seat, motor shaft stretch into the support cavity of electric machine stand 112, motor shaft be located at support cavity in position on be connected with motor
Axle coupling sleeve 113, is connected with outer magnetic group 1131 on motor shaft coupling sleeve 113, bearing block 116 is fixed on blind flange 121, stirring
Axle 118 is supported in bearing block 116, its upper end and is connected with interior magnetic group 114, and motor shaft coupling sleeve 113 is sheathed on interior magnetic group 114
On, be provided with cage 115 between motor shaft coupling sleeve 113 and interior magnetic group 114, cage 115 respectively with electric machine stand, bearing block
116 are tightly connected, the setting of separation sleeve, enable to bearing block inner space to be isolated from the outside, and reduce microbiological contamination probability.
The tail gas condensing pipe 125 connected with tank body 13 is connected with blind flange 121, tail gas condensing pipe 125 is provided with condensation
Component 14, condensation 14 includes the fixed aluminium block 142 of heat transfer, semiconductor chilling plate 143, fin 141 and radiator fan 144,
The fixed aluminium block 142 of heat transfer is provided with the groove 1421 of magnet and Longitudinal extending, the fixed mutual adhesives of aluminium block 142 of two heat transfers and
By the grooves hold tail gas condensing pipe 125 being oppositely arranged, semiconductor chilling plate 143, fin 141 are in turn secured to wherein one
On the end face opposite with groove of the individual fixed aluminium block 142 of heat transfer, radiator fan 144 is embedded with fin.Condensation passes through
Magnet adsorption mode is fixed on tail gas condensing pipe, and a step is dismantled a step and installed, and disassembly process is simply made excuses.The fixed aluminium block of heat transfer is straight
Connect and contacted with tail gas condensing pipe, cooling effect more preferably, makes tail gas condensing pipe temperature be easily reached below dew point.
Blind flange 121 is also provided with feed supplement joint 123, air tube assembly 124, temperature sleeves 126, level electrode component
127；Bump joint 128 and probe tube 129.Feed supplement joint is connected by the output end of expects pipe, joint and peristaltic pump, for feed supplement
Operation, machine cabinet body front side wall or arranged on left and right sides wall can open up through hole and be stretched out for feed supplement pipe；Air tube assembly 124 is fermentation tank
Air inlet；Temperature electrode is provided with temperature sleeves 126, to isolate electrode and nutrient solution；Level electrode component 127 is used to monitor to be sent out
Liquid level in fermentation tank；Flange connects 128 for pH, DO electrodes base；Probe tube 129 is sampling device for fermentation tank, one end connection
Silicone tube and sample connection, the other end are stretched under fermentation liquid level.
Tail gas condensing pipe includes guiding tube 1251, and the upper end of guiding tube 1251 is press-fited by swivel nut 1253 and is fixed with joint
1252, swivel nut 1253 is threadedly coupled with guiding tube 1251, and the bottom of joint 1252 is stretched into guiding tube 1251 and and guiding tube
Interval setting, the bottom of joint 1252 is threaded with flow-disturbing axle 1254, its tube wall and is provided with the water conservancy diversion connected with guiding tube
Hole 12531, flow-disturbing axle 1254 is provided with the flow-disturbing flange 12541 for radially extending, and the setting of flow-disturbing axle and flow-disturbing flange can make
Obtain tail gas and form turbulent flow, improve heat transfer effect.
The interior periphery of magnetic group 114 is coated with polytetrafluoroethylene floor, and polytetrafluoroethylene (PTFE) not only has self-lubricating effect, and can
Prevent the particulate matter that got rusty after interior magnetic group Long Term Contact steam or zymotic fluid, produced, so extend stirring system service life,
Reduce microbiological contamination risk.
Separation sleeve 115 is provided with cover body convex shoulder 1151, and bearing block is provided with pedestal convex shoulder 1161, the bottom of electric machine stand
The upper surface of cover body convex shoulder, upper end and the separation sleeve of bearing block 116 are threadedly coupled and are resisted against with the upper end of separation sleeve
Bottom threaded connection, its pedestal convex shoulder 1161 are resisted against on the lower surface of cover body convex shoulder 1151, cover body convex shoulder and pedestal convex shoulder
Between be embedded with sealing ring 119；Its simple structure, convenient disassembly, and good sealing effect.
Fermentation canister bracket is provided with U-type groove 222, case 223, and case 223 is rotated with the side of U-lag 222 and is connected and and U
The flange on shape groove opposite side top is fastened and connected；Fermentation tank has many accessories in use, and such as tongs, Rule connects
Head, electrode cap, O-ring etc., these accessories are concluded, deposited in U-lag, and U-type groove is opened using preceding rotation case, use process
In will easily take out very much required article, also article can smoothly be put back to after use, rotation case close U-type groove.
Containing cavities 226 are additionally provided with fermentation canister bracket, the both sides of receiver 224 are by link assembly 225 and the two of containing cavities
Side wall connection can be simultaneously housed with containing cavities, and link assembly includes first connecting rod and second connecting rod, first connecting rod one end and receipts
Receiving the side walls hinged of chamber, the other end and second connecting rod one end is hinged, the other end of second connecting rod and the side wall of receiver
It is hinged；Some storage capsules are divided into by dividing plate 2241 on receiver 224, are easy to pH electrodes, dissolved oxygen electricity in fermentation process
The sorting placement of the valuables such as pole.
Claims (9)
1. parallel multi-joint fermentation tank, it includes rack and fermentation tank, it is characterised in that：
The rack include machine cabinet body, the machine cabinet body top be provided with feed supplement bottle holder frame, sidepiece be provided with fermentation canister bracket, with
And accommodating cavity is provided with positioned at feed supplement bottle holder frame lower section, peristaltic pump is provided with the accommodating cavity, on the bottom wall of the feed supplement bottle holder frame
The through hole connected with the peristaltic pump accommodating cavity is provided with, the feed supplement pipe of feed supplement bottle connection connects peristaltic pump after the through hole
Input, the fermentation canister bracket is provided with some fermentation tanks；
The fermentation tank includes tank body and rabbling mechanism；
The upper end open of the tank body is encapsulated by end socket；
The rabbling mechanism includes motor, electric machine stand, bearing block and agitating shaft；The motor be fixed on electric machine stand seat it is upper,
Motor shaft is stretched into the support cavity of electric machine stand, and the motor shaft is located on the position in support cavity and is connected with motor shaft connection
Female connector, is connected with outer magnetic group on the motor shaft coupling sleeve, the bearing block is fixed on end socket, and the agitating shaft is supported in axle
Bearing, its upper end are connected with interior magnetic group, and the motor shaft coupling sleeve is sheathed in the interior magnetic group, the motor shaft coupling sleeve
Separation sleeve is provided between the interior magnetic group, the separation sleeve is tightly connected with the electric machine stand, bearing block respectively.
2. parallel multi-joint fermentation tank according to claim 1, it is characterised in that：The end socket includes blind flange and flange
Circle, the upper end of the tank body is provided with the flange for extending laterally, and the blind flange is installed on the flange upside end face and covers
Close the upper end open of tank body, the flange snare is located at the tank body and is resisted against the downside end face of flange, the blind flange and
The flange circle is connected by bolt, nut assembly；The blind flange downside is provided with the sealing ring with the lip fits.
3. parallel multi-joint fermentation tank according to claim 2, it is characterised in that：It is connected with the blind flange and the tank
The tail gas condensing pipe of body connection, the tail gas condensing pipe is provided with condensation, the condensation include the fixed aluminium block of heat transfer,
The groove that aluminium block is provided with magnet and Longitudinal extending, two are fixed in semiconductor chilling plate, fin and radiator fan, the heat transfer
The fixed aluminium block of heat transfer passes through the mutual adhesive of magnet and the grooves hold tail gas condensing pipe by being oppositely arranged, the semiconductor system
Cold, fin be in turn secured on end face opposite with groove of the fixed aluminium block of one of heat transfer, set on the fin
There is radiator fan.
4. parallel multi-joint fermentation tank according to claim 3, it is characterised in that：The tail gas condensing pipe includes guiding tube,
The upper end of the guiding tube is press-fited by swivel nut and is fixed with joint, and the swivel nut is threadedly coupled with guiding tube, the joint
Bottom stretch into the guiding tube and with the guiding tube interval setting, the bottom of the joint is threaded with flow-disturbing
Axle, its tube wall are provided with the pod apertures connected with the guiding tube, and the flow-disturbing axle is provided with the flow-disturbing flange for radially extending.
5. parallel multi-joint fermentation tank according to claim 1, it is characterised in that：The separation sleeve is provided with cover body convex shoulder,
The bearing block is provided with pedestal convex shoulder, the bottom of the electric machine stand be threadedly coupled with the upper end of separation sleeve and against
In the upper surface of the cover body convex shoulder, the upper end of the bearing block is threadedly coupled with the bottom of separation sleeve, its pedestal convex shoulder
It is resisted against on the lower surface of cover body convex shoulder, sealing ring is embedded between the cover body convex shoulder and the pedestal convex shoulder.
6. parallel multi-joint fermentation tank according to claim 1, it is characterised in that：The fermentation canister bracket be provided with U-type groove,
Case, the case rotates with the U-lag side and is connected and can be fastened on the case.
7. parallel multi-joint fermentation tank according to claim 6, it is characterised in that：Storage is additionally provided with the fermentation canister bracket
Chamber, receiver both sides be connected with the two side of the containing cavities by link assembly and can house with the containing cavities.
8. parallel multi-joint fermentation tank according to claim 1, it is characterised in that：The interior magnetic group periphery is coated with polytetrafluoro
Pvdf layer.
9. parallel multi-joint fermentation tank according to claim 1, it is characterised in that：Opened on the front side wall of the feed supplement bottle holder frame
It is provided with form.
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| CN201611029332.8A CN106754305A (en) | 2016-11-22 | 2016-11-22 | Parallel multi-joint fermentation tank |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201611029332.8A CN106754305A (en) | 2016-11-22 | 2016-11-22 | Parallel multi-joint fermentation tank |
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| CN106754305A true CN106754305A (en) | 2017-05-31 |
Family
ID=58970734
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| Application Number | Title | Priority Date | Filing Date |
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| CN201611029332.8A Pending CN106754305A (en) | 2016-11-22 | 2016-11-22 | Parallel multi-joint fermentation tank |
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| CN (1) | CN106754305A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107267389A (en) * | 2017-08-23 | 2017-10-20 | 湖南开启时代生物科技有限责任公司 | A kind of cell expansion apparatus |
| CN108467823A (en) * | 2018-06-19 | 2018-08-31 | 汇森生物设备镇江有限公司 | A kind of full-automatic multi-joint mechanical agitation glass fermentation tank |
| CN109401951A (en) * | 2018-11-09 | 2019-03-01 | 上海主元生物科技有限公司 | A kind of micromation high throughput installation for fermenting |
| CN109401950A (en) * | 2018-11-09 | 2019-03-01 | 上海主元生物科技有限公司 | Magnetic stirring apparatus and heating refrigeration system for micromation installation for fermenting |
| CN110331077A (en) * | 2019-08-22 | 2019-10-15 | 安徽省益丰生态农业科技有限公司 | A kind of thick chilli sauce Zymolysis Equipment and its technique |
| CN113025485A (en) * | 2021-03-17 | 2021-06-25 | 厦门大学 | Continuous foam separation coupling fermentation device |
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| CN109401950A (en) * | 2018-11-09 | 2019-03-01 | 上海主元生物科技有限公司 | Magnetic stirring apparatus and heating refrigeration system for micromation installation for fermenting |
| CN110331077A (en) * | 2019-08-22 | 2019-10-15 | 安徽省益丰生态农业科技有限公司 | A kind of thick chilli sauce Zymolysis Equipment and its technique |
| CN113025485A (en) * | 2021-03-17 | 2021-06-25 | 厦门大学 | Continuous foam separation coupling fermentation device |
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