CN106728981A - A kind of common jujube root Zhixue soluble granules and preparation method thereof - Google Patents

A kind of common jujube root Zhixue soluble granules and preparation method thereof Download PDF

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CN106728981A
CN106728981A CN201510799609.4A CN201510799609A CN106728981A CN 106728981 A CN106728981 A CN 106728981A CN 201510799609 A CN201510799609 A CN 201510799609A CN 106728981 A CN106728981 A CN 106728981A
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parts
seed
root
common jujube
zhixue
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马玉国
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Harbin Shengji Pharmaceutical Co Ltd
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Harbin Shengji Pharmaceutical Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/36Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/748Oldenlandia or Hedyotis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

A kind of common jujube root Zhixue soluble granules, it is prepared from following components in parts by weight by raw material, common jujube root 35-45 parts, bamboo juice 15-25 parts, nutgall 15-25 parts, holly leaf 10-15 parts, seed of feather cockscomb 10-15 parts, oldenlandia diffusa 10-15 parts, root bark of Chinese wolf-berry 10-15 parts, caulis trachelospermi 5-10 parts, radix cynanchi atrati 5-10 parts, akebi 5-10 parts, seed of cowherb 5-10 parts, sword bean 5-10 parts, rock sugar 4-8 parts, brown sugar 4-8 parts, resistant dextrin 4-8 parts, D-sorbite 4-8 parts, its preparation method is mainly comprised the following steps:Step 1, pretreatment of raw material;Step 2, crushing, mixing;Step 3, decoction, cooling;Step 4, filtering, extraction, concentration; Step 5, drying, crushing;Step 6, sterilizing, pack.One kind of the invention Common jujube root Zhixue soluble granules, with hemostasis, heat phlegm, solid and gas effect.

Description

A kind of common jujube root Zhixue soluble granules and preparation method thereof
Technical field
The present invention relates to technical field of food healthcare, particularly a kind of common jujube root Zhixue soluble granules and preparation method thereof.
Background technology
Spit blood:More because pungent fertile, the disgruntled troubled thoughts of addiction wine heat, labor are intended to physically weak etc., cause hyperpyrexia of stomach, liver depression forming fire, or heart spleen The deficiency of vital energy, blood loses to control and forms.Also have because of diseases caused by external factors priming person.Haematemesis is divided into exogenous hemptysis, hematemesis with internal injury, asthenia yin hemoptysis, works with one's mind and tell Blood, over-strained hemoptysis, depressed haematemesis, poultry hot haematemesis, stomach impairment, haematemesis etc. of getting sick from drinking too much wine, refer to each bar.Blood by stomach and esophagus, Oral to spue, color is red or purple dim, and normal mixing with food residue is referred to as spitted blood, also referred to as spitting blood.The digestibility for being common in doctor trained in Western medicine is burst UGB caused by the disease such as ulcer, chronic gastritis, cirrhosis, stomach cancer.
The medicine of various hemostasis is currently there are, but the effect of most drug is not fine, and also With side effect, the health of human body can be damaged.Therefore, one kind is badly in need of in the market can stop blooding, it is heat phlegm, solid The common jujube root Zhixue soluble granules and its production method of gas.
The content of the invention
It is an object of the invention to provide it is a kind of with hemostasis, heat phlegm, the common jujube root Zhixue soluble granules of solid and gas effect and its Preparation method.
The purpose of the present invention is achieved through the following technical solutions:
A kind of common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, common jujube root 35-45 parts, bamboo juice 15-25 Part, nutgall 15-25 parts, holly leaf 10-15 parts, seed of feather cockscomb 10-15 parts, oldenlandia diffusa 10-15 parts, root bark of Chinese wolf-berry 10-15 parts, Caulis trachelospermi 5-10 parts, radix cynanchi atrati 5-10 parts, akebi 5-10 parts, seed of cowherb 5-10 parts, sword bean 5-10 parts, rock sugar 4-8 parts, brown sugar 4- 8 parts, resistant dextrin 4-8 parts, D-sorbite 4-8 parts.
A kind of described common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, 45 parts of common jujube root, bamboo juice 25 parts, it is 25 parts of nutgall, 13 parts of holly leaf, 13 parts of seed of feather cockscomb, 13 parts of oldenlandia diffusa, 13 parts of the root bark of Chinese wolf-berry, 5 parts of caulis trachelospermi, white 5 parts of common vetch, 5 parts of akebi, 5 parts of the seed of cowherb, 5 parts of sword bean, 8 parts of rock sugar, 6 parts of brown sugar, 4 parts of resistant dextrin, 4 parts of D-sorbite.
A kind of described common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, 40 parts of common jujube root, bamboo juice 20 parts, it is 20 parts of nutgall, 10 parts of holly leaf, 10 parts of seed of feather cockscomb, 10 parts of oldenlandia diffusa, 10 parts of the root bark of Chinese wolf-berry, 8 parts of caulis trachelospermi, white 8 parts of common vetch, 8 parts of akebi, 8 parts of the seed of cowherb, 8 parts of sword bean, 6 parts of rock sugar, 4 parts of brown sugar, 4 parts of resistant dextrin, 4 parts of D-sorbite.
A kind of described common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, 35 parts of common jujube root, bamboo juice 15 parts, it is 15 parts of nutgall, 15 parts of holly leaf, 15 parts of seed of feather cockscomb, 15 parts of oldenlandia diffusa, 15 parts of the root bark of Chinese wolf-berry, 10 parts of caulis trachelospermi, white 10 parts of common vetch, 10 parts of akebi, 10 parts of the seed of cowherb, 10 parts of sword bean, 7 parts of rock sugar, 5 parts of brown sugar, 5 parts of resistant dextrin, D-sorbite 4 Part.
A kind of described common jujube root Zhixue soluble granules, its preparation method is mainly comprised the following steps:
Step 1, pretreatment of raw material:By weight, the common jujube root of high-quality, bamboo juice, nutgall, holly leaf, seed of feather cockscomb, white is chosen Flower HERBA HEDYOTIS DIFFUSAE, the root bark of Chinese wolf-berry, caulis trachelospermi, radix cynanchi atrati, akebi, the seed of cowherb, sword bean, clean and removal of impurities, standby;
Step 2, crushing, mixing:By weight, respectively take clean and removal of impurities after common jujube root, bamboo juice, nutgall, holly leaf, Seed of feather cockscomb, oldenlandia diffusa, the root bark of Chinese wolf-berry, caulis trachelospermi, radix cynanchi atrati, akebi, the seed of cowherb, sword bean, are respectively put into crushing in pulverizer Into particle, 50-60 mesh sieves are crossed, hybrid particles are standby;
Step 3, decoction, cooling:The distilled water of 10-12 times of total amount is added in hybrid particles, first 30-40 is boiled in heating with high heat Minute, then with being cooked by slow fire 2-3 hours, rock sugar, brown sugar, resistant dextrin, D-sorbite are subsequently adding, add 6-8 times of steaming Distilled water, continues with being cooked by slow fire 1.5-2 hours, is cooled to room temperature, obtains mixed solution, standby;
Step 4, filtering, extraction, concentration:Mixed solution is carried out into fine filtering, 95% ethanol is added and is stirred and carried Take, a point liquid is carried out after standing, then 2~3 times of distilled water are added to the supernatant liquid after point liquid, then carry out heating and be concentrated into relatively Density is 1.2~3 paste, and reclaims ethanol;
Step 5, drying, crushing:Paste solution after concentration is dried at a temperature of 75-85 DEG C, is crushed after being cooled to room temperature, 70-80 mesh sieves are crossed, solid particle is obtained;
Step 6, sterilizing, pack:Solid particle is taken, is sterilized by the way of ultraviolet disinfection, packed after sterilizing, a kind of jujube is obtained Tree root Zhixue soluble granules.
In medicine:Jujube tree effects a radical cure joint pain, and stomachache is spitted blood, metrorrhagia, irregular menstruation, rubella, erysipelas, bamboo juice heat-clearing Slit phlegm, for heap soil or fertilizer over and around the roots of apoplexy phlegm, dyspnea and cough due to lung-heat, pyreticosis is irritated, and nutgall solid and gas, puckery essence is astringed the lung, and stops blooding;Control large intestine empty sliding, rush down dysentery Incessantly, have blood in stool, pass out semen, cloudy sweat, cough, spitting of blood, dentalgia, traumatic bleeding, sore does not close up long, holly leaf clearing heat and nourishing yin, soothing the liver, Kidney-nourishing;For tuberculosis spitting of blood, osteopyrexia and fever is had a dizzy spell;Hypertension, seed of feather cockscomb is cleared liver, and screen is moved back in improving eyesight;For the hot hot eyes of liver, Screen of looking unfamiliar film, blurring of vision, hepatopyretic vertigo, oldenlandia diffusa is clearing heat and detoxicating;Dampness removing;Main dyspnea and cough due to lung-heat;Abscess of throat;Acute appendicitis; Furuncle sore;Venomous snake bite;Puckery pain of heat gonorrhea;Water;Dysentery;Enteritis;Jaundice with damp-heat pathogen;Cancerous swelling, root bark of Chinese wolf-berry cool blood except steaming, drop by clearing lung-heat Fire;For deficiency of Yin hectic fever, hectic fever due to yin night sweat, cough with lung heat, spitting of blood, bleeding from five sense organs or subcutaneous tissue, Heat Diabetes, caulis trachelospermi dispelling wind and removing obstruction in the meridians, cool blood detumescence; For beriberoid pyretic arthralgia, muscle arteries and veins contraction, soreness of waist and knee joint, larynx numbness, carbuncle swells, injury from falling down, radix cynanchi atrati heat-clearing, cool blood;Control yin asthenia generating intrinsic heat, wind The scorching hot many dormancies of temperature, lung heat hemoptysis, a kind of malaria, malaria, postpartum dysphoria blood is fainted, heat gonorrhea, blood strangury, rheumatalgia, scrofula, akebi purging intense heat row Water, it is promoting blood circulation;Hot urination is controlled, stranguria with turbid discharge, oedema is irritable feverish sensation in chest, larynx numbness pharyngalgia, inflexible pain all over, women's Amenorrhea, and milk is not It is logical, seed of cowherb invigorate blood circulation, lower breast detumescence;For agalactia, Amenorrhea, dysmenorrhoea, acute mastitis swells and ache, sword bean middle benefit gas, lower gas, only Oh;For cold of insufficiency type hiccup, vomiting.
Beneficial effects of the present invention:A kind of common jujube root Zhixue soluble granules of the invention, drink with heat phlegm, only for a long time Effect of blood, solid and gas, has the advantages that health care, instant effect, pure natural, no side effectses.
Through two groups of clinical verifications, one of which drinks the present invention to the present invention for treatment group, and the present invention is drunk daily once, and 7 It is a course for the treatment of, and another group of control group takes hemostasis capsule, is within 7 days a course for the treatment of, per group selection outpatient service daily using once Patient 110, wherein man 55, female 55, max age 75 years old, minimal ages 35 years old, to ache, stomachache is told for clinical manifestation Blood, metrorrhagia, rubella, erysipelas, table one is to take the contrasting data after a course for the treatment of:
Table 1 takes front and rear two groups of courses for the treatment of and compares (unit:People)
There were significant differences for treatment group and control group, it will thus be seen that present invention application clinically has significant curative effect.
Technological advantage of the invention is:1st, raw material science is selected, production technology is advanced;2nd, in product without spices and Preservative, keeps raw material local flavor in itself and nutrition, is easily absorbed by the body;3rd, raw material sources are extensive, plus process line is short, Product easy processing is manufactured.
Specific embodiment
Embodiment 1
A kind of common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, common jujube root 35-45 parts, bamboo juice 15-25 Part, nutgall 15-25 parts, holly leaf 10-15 parts, seed of feather cockscomb 10-15 parts, oldenlandia diffusa 10-15 parts, root bark of Chinese wolf-berry 10-15 parts, Caulis trachelospermi 5-10 parts, radix cynanchi atrati 5-10 parts, akebi 5-10 parts, seed of cowherb 5-10 parts, sword bean 5-10 parts, rock sugar 4-8 parts, brown sugar 4- 8 parts, resistant dextrin 4-8 parts, D-sorbite 4-8 parts.
Its preparation method is mainly comprised the following steps:
Step 1, pretreatment of raw material:By weight, the common jujube root of high-quality, bamboo juice, nutgall, holly leaf, seed of feather cockscomb, white is chosen Flower HERBA HEDYOTIS DIFFUSAE, the root bark of Chinese wolf-berry, caulis trachelospermi, radix cynanchi atrati, akebi, the seed of cowherb, sword bean, clean and removal of impurities, standby;
Step 2, crushing, mixing:By weight, respectively take clean and removal of impurities after common jujube root, bamboo juice, nutgall, holly leaf, Seed of feather cockscomb, oldenlandia diffusa, the root bark of Chinese wolf-berry, caulis trachelospermi, radix cynanchi atrati, akebi, the seed of cowherb, sword bean, are respectively put into crushing in pulverizer Into particle, 50-60 mesh sieves are crossed, hybrid particles are standby;
Step 3, decoction, cooling:The distilled water of 10-12 times of total amount is added in hybrid particles, first 30-40 is boiled in heating with high heat Minute, then with being cooked by slow fire 2-3 hours, rock sugar, brown sugar, resistant dextrin, D-sorbite are subsequently adding, add 6-8 times of steaming Distilled water, continues with being cooked by slow fire 1.5-2 hours, is cooled to room temperature, obtains mixed solution, standby;
Step 4, filtering, extraction, concentration:Mixed solution is carried out into fine filtering, 95% ethanol is added and is stirred and carried Take, a point liquid is carried out after standing, then 2~3 times of distilled water are added to the supernatant liquid after point liquid, then carry out heating and be concentrated into relatively Density is 1.2~3 paste, and reclaims ethanol;
Step 5, drying, crushing:Paste solution after concentration is dried at a temperature of 75-85 DEG C, is crushed after being cooled to room temperature, 70-80 mesh sieves are crossed, solid particle is obtained;
Step 6, sterilizing, pack:Solid particle is taken, is sterilized by the way of ultraviolet disinfection, packed after sterilizing, a kind of jujube is obtained Tree root Zhixue soluble granules.
Embodiment 2
A kind of described common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, 45 parts of common jujube root, bamboo juice 25 Part, 25 parts of nutgall, 13 parts of holly leaf, 13 parts of seed of feather cockscomb, 13 parts of oldenlandia diffusa, 13 parts of the root bark of Chinese wolf-berry, 5 parts of caulis trachelospermi, radix cynanchi atrati 5 Part, 5 parts of akebi, 5 parts of the seed of cowherb, 5 parts of sword bean, 8 parts of rock sugar, 6 parts of brown sugar, 4 parts of resistant dextrin, 4 parts of D-sorbite.
Its preparation method is identical with embodiment 1.
Embodiment 3
A kind of described common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, 40 parts of common jujube root, bamboo juice 20 Part, 20 parts of nutgall, 10 parts of holly leaf, 10 parts of seed of feather cockscomb, 10 parts of oldenlandia diffusa, 10 parts of the root bark of Chinese wolf-berry, 8 parts of caulis trachelospermi, radix cynanchi atrati 8 Part, 8 parts of akebi, 8 parts of the seed of cowherb, 8 parts of sword bean, 6 parts of rock sugar, 4 parts of brown sugar, 4 parts of resistant dextrin, 4 parts of D-sorbite.
Its preparation method is identical with embodiment 1.
Embodiment 4
A kind of described common jujube root Zhixue soluble granules, are prepared from following components in parts by weight by raw material, 35 parts of common jujube root, bamboo juice 15 Part, 15 parts of nutgall, 15 parts of holly leaf, 15 parts of seed of feather cockscomb, 15 parts of oldenlandia diffusa, 15 parts of the root bark of Chinese wolf-berry, 10 parts of caulis trachelospermi, radix cynanchi atrati 10 parts, 10 parts of akebi, 10 parts of the seed of cowherb, 10 parts of sword bean, 7 parts of rock sugar, 5 parts of brown sugar, 5 parts of resistant dextrin, 4 parts of D-sorbite.
Its preparation method is identical with embodiment 1.

Claims (5)

1. a kind of common jujube root Zhixue soluble granules, it is characterised in that:It is prepared from following components in parts by weight by raw material, common jujube root 35-45 Part, bamboo juice 15-25 parts, nutgall 15-25 parts, holly leaf 10-15 parts, seed of feather cockscomb 10-15 parts, oldenlandia diffusa 10-15 parts, 10-15 parts of bone skin, caulis trachelospermi 5-10 parts, radix cynanchi atrati 5-10 parts, akebi 5-10 parts, seed of cowherb 5-10 parts, sword bean 5-10 parts, rock sugar 4-8 parts, brown sugar 4-8 parts, resistant dextrin 4-8 parts, D-sorbite 4-8 parts.
2. a kind of common jujube root Zhixue soluble granules according to claim 1, it is characterised in that:Following weight portion numeral system is pressed by raw material It is standby to form, 45 parts of common jujube root, 25 parts of bamboo juice, 25 parts of nutgall, 13 parts of holly leaf, 13 parts of seed of feather cockscomb, 13 parts of oldenlandia diffusa, 13 parts of bone skin, 5 parts of caulis trachelospermi, 5 parts of radix cynanchi atrati, 5 parts of akebi, 5 parts of the seed of cowherb, 5 parts of sword bean, 8 parts of rock sugar, 6 parts of brown sugar, resistance paste Smart 4 parts, 4 parts of D-sorbite.
3. a kind of common jujube root Zhixue soluble granules according to claim 1, it is characterised in that:Following weight portion numeral system is pressed by raw material It is standby to form, 40 parts of common jujube root, 20 parts of bamboo juice, 20 parts of nutgall, 10 parts of holly leaf, 10 parts of seed of feather cockscomb, 10 parts of oldenlandia diffusa, 10 parts of bone skin, 8 parts of caulis trachelospermi, 8 parts of radix cynanchi atrati, 8 parts of akebi, 8 parts of the seed of cowherb, 8 parts of sword bean, 6 parts of rock sugar, 4 parts of brown sugar, resistance paste Smart 4 parts, 4 parts of D-sorbite.
4. a kind of common jujube root Zhixue soluble granules according to claim 1, it is characterised in that:Following weight portion numeral system is pressed by raw material It is standby to form, 35 parts of common jujube root, 15 parts of bamboo juice, 15 parts of nutgall, 15 parts of holly leaf, 15 parts of seed of feather cockscomb, 15 parts of oldenlandia diffusa, 15 parts of bone skin, 10 parts of caulis trachelospermi, 10 parts of radix cynanchi atrati, 10 parts of akebi, 10 parts of the seed of cowherb, 10 parts of sword bean, 7 parts of rock sugar, 5 parts of brown sugar, 5 parts of resistant dextrin, 4 parts of D-sorbite.
5. a kind of common jujube root Zhixue soluble granules according to claim 1-4, it is characterised in that:The key step of its preparation method For:
Step 1, pretreatment of raw material:By weight, the common jujube root of high-quality, bamboo juice, nutgall, holly leaf, seed of feather cockscomb, white is chosen Flower HERBA HEDYOTIS DIFFUSAE, the root bark of Chinese wolf-berry, caulis trachelospermi, radix cynanchi atrati, akebi, the seed of cowherb, sword bean, clean and removal of impurities, standby;
Step 2, crushing, mixing:By weight, respectively take clean and removal of impurities after common jujube root, bamboo juice, nutgall, holly leaf, Seed of feather cockscomb, oldenlandia diffusa, the root bark of Chinese wolf-berry, caulis trachelospermi, radix cynanchi atrati, akebi, the seed of cowherb, sword bean, are respectively put into crushing in pulverizer Into particle, 50-60 mesh sieves are crossed, hybrid particles are standby;
Step 3, decoction, cooling:The distilled water of 10-12 times of total amount is added in hybrid particles, first 30-40 is boiled in heating with high heat Minute, then with being cooked by slow fire 2-3 hours, rock sugar, brown sugar, resistant dextrin, D-sorbite are subsequently adding, add 6-8 times of steaming Distilled water, continues with being cooked by slow fire 1.5-2 hours, is cooled to room temperature, obtains mixed solution, standby;
Step 4, filtering, extraction, concentration:Mixed solution is carried out into fine filtering, 95% ethanol is added and is stirred and carried Take, a point liquid is carried out after standing, then 2~3 times of distilled water are added to the supernatant liquid after point liquid, then carry out heating and be concentrated into relatively Density is 1.2~3 paste, and reclaims ethanol;
Step 5, drying, crushing:Paste solution after concentration is dried at a temperature of 75-85 DEG C, is crushed after being cooled to room temperature, 70-80 mesh sieves are crossed, solid particle is obtained;
Step 6, sterilizing, pack:Solid particle is taken, is sterilized by the way of ultraviolet disinfection, packed after sterilizing, a kind of jujube is obtained Tree root Zhixue soluble granules.
CN201510799609.4A 2015-11-19 2015-11-19 A kind of common jujube root Zhixue soluble granules and preparation method thereof Withdrawn CN106728981A (en)

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Citations (2)

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Publication number Priority date Publication date Assignee Title
CN104258087A (en) * 2014-10-23 2015-01-07 陈济超 Heat-clearing, blood-cooling and blood-stanching drug for woman menorrhagia and preparation method thereof
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Publication number Priority date Publication date Assignee Title
CN104258087A (en) * 2014-10-23 2015-01-07 陈济超 Heat-clearing, blood-cooling and blood-stanching drug for woman menorrhagia and preparation method thereof
CN104435950A (en) * 2014-11-06 2015-03-25 赵霞 Traditional Chinese medicinal styptic powder for treating upper gastrointestinal hemorrhage and preparation method thereof

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Application publication date: 20170531