CN106728710A - A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction - Google Patents
A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction, the Chinese medicine composition is made up of following bulk drug：Semen Agriophylli Squarrosi, terrible lid, pomelo flower, Taibai Lily Herb, bitter citrus immature flower, jasmine, silk tree, Momordica grosvenori, balloonflower root, all kusamaki broad-leaved podocarpus seed and receptacle, drawing, scarlet swertia herb, caecum grass.The Chinese medicine composition of the treatment primary chronic intestinal pseudo obstruction that the present invention is provided, has filled up in the prior art without the deficiency for primary chronic intestinal pseudo obstruction special-purpose medicaments, treats primary chronic intestinal pseudo obstruction satisfactory effect, and recurrence rate is low.
Description
Technical field
The present invention relates to Chinese medicine sciemtifec and technical sphere, more particularly to a kind of Chinese traditional medicine composition for treating primary chronic intestinal pseudo obstruction
Thing.
Background technology
Primary chronic intestinal pseudo obstruction is a kind of without mechanical obstruction factor but with ileus symptoms, with intestines and stomach
Lack and coordinate the clinical syndrome that transportation function is characterized.Primary chronic intestinal pseudo obstruction is by intestinal smooth exception or intestines
Nervous system abnormality is caused.Disease recurrence is frequent, and state of an illness weight interindividual variation is very big.At present without treatment primary chronic
The active drug of intestinal pseudo obstruction, does not find the clinical report for the treatment of by Chinese herbs primary chronic intestinal pseudo obstruction yet.It is in a bad way
Person often needs the treatment such as row gastrointestinal decompression, nutritional support, Ceostomy, the excision of part intestinal tube.Operation and other treatments and health
It is multiple that very big pain, or the breaking-out for triggering other diseases are caused to patient.In order to solve this problem, advantages of TCM is played,
The special-purpose medicaments of research and development treatment primary chronic intestinal pseudo obstruction have important clinical significance.The present inventor passes through clinical practice,
A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction is developed, clinical efficacy is notable
The content of the invention
It is an object of the invention to overcome in the prior art without for primary chronic intestinal pseudo obstruction special-purpose medicaments no
Put forward enough, that is, one kind is provided and treats primary chronic intestinal pseudo obstruction Chinese medicine composition.
In order to realize foregoing invention purpose, the invention provides following technical scheme：
A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction, is made up of the bulk drug of following mass ratio：
Semen Agriophylli Squarrosi 9-15 parts, ghost lid 5-7 parts, pomelo flower 2-4 parts, Taibai Lily Herb 4-6 parts, bitter citrus immature flower 1-3 parts, jasmine 6-10
Part, silk tree 5-7 parts, Momordica grosvenori 15-25 parts, balloonflower root 6-10 parts, kusamaki broad-leaved podocarpus seed and receptacle 10-20 parts, all drawing 15-25 parts, scarlet swertia herb
8-12 parts, 20-30 parts of caecum grass.
Semen Agriophylli Squarrosi：It is sweet, flat, return lung, spleen, stomach.《Detailed outline is picked up any lost article from the road》" tonneau large intestine, disappear place food ".
Ghost lid：Sweet, flat, mild toxicity.Beneficial stomach, phlegm-eliminiating and qi-regulating, removing toxicity for detumescence.Poor appetite is cured mainly, cough is spat, children's epilepsy
Disease, stagnation of the circulation of vital energy distending pain, malignant boil swells sore.
Pomelo flower：Promoting the circulation of qi, resolving sputum, analgesic.Cure mainly gastral cavilty chest diaphragm distending pain.
Taibai Lily Herb：Pungent, bitter, tepor.Chest profit gas wide, stomach invigorating, preventing or arresting vomiting, analgesia, cough-relieving.Stomachache abdominal distension is cured mainly, uncomfortable in chest, vomiting
Gastric disorder causing nausea, cough due to wind-cold evil, child convulsion.
Bitter citrus immature flower：It is pungent, sweet, slight bitter, flat.Qi-regulating chest wide, anti-vomiting.Cure mainly ruffian in the heart vexed, abdominal distention does not think drink
Food, n and V.
Jasmine：It is flat, nontoxic.Soothing liver-qi stagnation, promoting qi circulation and relieving pain.Cure mainly the side of body rib caused by stagnation of QI due to depression of the liver to have a pain, diarrhea stomachache.
Silk tree：Pungent, temperature.Promoting the circulation of qi dissolving stasis, cough-relieving stop-band.Cure mainly the distending pain in hypochondrium, swollen breasts, hernia pain , wei lumps in the abdomen, bruise
Damage, insomnia, cough and asthma, leukorrhea.
Momordica grosvenori：It is sweet, cool, return lung, the spleen channel.Clearing lung-heat, resolving sputum, cough-relieving, ease constipation.Cure mainly phlegm-fire cough, pertussis, throat
Inflammation, tonsillitis, acute gastritis, constipation.
Balloonflower root：It is bitter, pungent, flat, return lung warp.Facilitaing lung, eliminating the phlegm, relieving sore-throat, apocenosis.Coughing with a lot of sputum is cured mainly, uncomfortable in chest not smooth, throat swells
Bitterly, aphonia, lung carbuncle pyemesis.
Kusamaki broad-leaved podocarpus seed and receptacle：Sweet, tepor.Promoting qi circulation and relieving pain, blood-nourishing.Cure mainly gastral cavity pain, deficiency of blood sallow complexion.
All draw：Sweet, slight bitter, tepor, return lung, spleen, kidney channel.Warm kidney QI invigorating, promoting blood circulation and hemostasis.Body deadhead dusk is cured mainly, consumptive disease is long
Cough, insufficiency of the spleen dyspepsia, lumbago due to the kidney deficiency, under band, impotence is infertile, rheumatic heart disease, traumatism and bleeding, bruise internal lesion caused by overexertion.
Scarlet swertia herb：It is bitter, cold.It is clearing heat and detoxicating, clearing damp stomach invigorating.Cure mainly indigestion, acute osteomyelitis, acute icteric liver
Inflammation, acute dysentery, acute conjunctivitis, acute laryngopharyngitis, burn and scald.
Caecum grass：It is sweet, slight bitter, cool.Heat-clearing, removing toxic substances, dampness removing, invigorating the spleen.Cure mainly influenza, abscess of throat, jaundice, summer-heat and damp
Vomit and diarrhoea, dysentery, acute appendicitis, infantile malnutrition, the deficiency of blood is yellow swollen.
Traditional Chinese medicine thinks primary chronic intestinal pseudo obstruction without " real evil " retardance, but with ileus symptoms, its " sheet " is
Visceral dysfunction, its " mark " is the card that mechanism of qi stops up resistance.Because in lung governing qi and large intestine phase table, liver controlling conveyance and dispersion, the main gasification of kidney, lung,
Liver, kidney and Qi dysfunction are in close relations, and sick many recurrent exerbations, and prolonged illness must be empty.Therefore suitable stomach invigorating profit gas is controlled, soothing the liver facilitaing lung,
Warm kidney blood-nourishing, it is clearing heat and detoxicating.The present invention is using Semen Agriophylli Squarrosi, ghost lid, pomelo flower stomach invigorating profit gas；Taibai Lily Herb, bitter citrus immature flower anti-vomiting；Element
Fragrant flower, silk tree soothing liver-qi stagnation, promoting qi circulation and relieving pain；Because of the lung and the large intestine being interior-exteriorly related, the clear facilitaing lung gas of Momordica grosvenori, balloonflower root, then large intestine mechanism of qi
Obtain freely, and Momordica grosvenori ease constipation is with logical abdomen gas；Kusamaki broad-leaved podocarpus seed and receptacle promoting the circulation of qi blood-nourishing；Warm kidney is all drawn to help gas row；Scarlet swertia herb, caecum grass are clear
Thermal detoxification, makes scorchingly hot clear and large intestine gas is certainly logical.All medicines share, treats both principal and secondary aspect of disease, therefore receives prompt effect.
Preferably, it is described treatment primary chronic intestinal pseudo obstruction Chinese medicine composition by following mass ratio bulk drug
It is made：
12 parts of Semen Agriophylli Squarrosi, terrible 6 parts of lid, 3 parts of pomelo flower, 5 parts of Taibai Lily Herb, 2 parts of bitter citrus immature flower, 8 parts of jasmine, 6 parts of silk tree, sieve
20 parts of Chinese fruit, 8 parts of balloonflower root, all 15 parts of kusamaki broad-leaved podocarpus seed and receptacle, 20 parts of drawing, 10 parts of scarlet swertia herb, 25 parts of caecum grass.
The Chinese medicine composition of the treatment primary chronic intestinal pseudo obstruction can be prepared using existing Chinese medicine preparation technique
Into any conventional oral preparations, for example, said components can be obtained water decoction using decocting, can also by other it is existing in
Medicine preparation technique by it is described treatment primary chronic intestinal pseudo obstruction Chinese medicine composition prepare piece agent, water-honeyed pill, capsule,
Powder, paste, oral liquid, granule.
Compared with prior art, beneficial effects of the present invention
The Chinese medicine composition of the treatment primary chronic intestinal pseudo obstruction that the present invention is provided, has filled up needleless in the prior art
To the deficiency of primary chronic intestinal pseudo obstruction special-purpose medicaments, primary chronic intestinal pseudo obstruction satisfactory effect, recurrence rate are treated
It is low.
A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction, clinical efficacy is summarized
1 clinical data
102 patients are randomly divided into treatment group and control group, every group 51.Year at treatment group's age (43.8 ± 8.4), the course of disease
(3.5 ± 1.1) year.Year at control group age (44.0 ± 7.2), the course of disease (3.4 ± 1.2) year.Two groups of patient ages, courses of disease etc. are general
Situation compares, no significant difference (P ＞ 0.05), with comparativity.
2 diagnostic criteria
1. clinically there is the sings and symptoms of intestinal obstruction.2. abdominal X-ray plain confirms the presence for having intestinal obstruction.3. relevant inspection
Find out and really eliminate mechanical ileus.4. gastrointestinal image inspection finds the expansion for having intestinal tube, or enterocinesia substantially slows down, disappears
Lose.5. gastrointestinal pressure determines abnormal, gastrointestinal transit time and is obviously prolonged 6. to exclude can cause subsequent chronic intestinal pseudo obstruction
Disease (such as ICT, autoimmune disease).[square Xiucai, Ke Meiyun, Liu Xiaohong wait the false intestines of primary chronics
The Clinical symptoms of obstruction and diagnosis CHINESE JOURNAL OF INTERNAL MEDICINEs .2001,40 (10)：666-669.」.
3 treatment methods
Control group is oral using Cisapride, each 10mg, and 3 times a day, is within 5 days 1 course for the treatment of；Treatment group is orally of the invention
The Chinese medicine preparation water decoction of offer is 1 course for the treatment of in 5 days, and prescription is as follows：
12 grams of Semen Agriophylli Squarrosi, terrible 6 grams of lid, 3 grams of pomelo flower, 5 grams of Taibai Lily Herb, 2 grams of bitter citrus immature flower, 8 grams of jasmine, 6 grams of silk tree, sieve
20 grams of Chinese fruit, 8 grams of balloonflower root, all 15 grams of kusamaki broad-leaved podocarpus seed and receptacle, 20 grams of drawing, 10 grams of scarlet swertia herb, 25 grams of caecum grass.According to conventional Chinese medicine system
Agent technology is made water decoction, everyone daily 1 dose.Two groups are treated 1 course for the treatment of.
4 treatment results
4.1 criterions of therapeutical effect：
Cure：Without abdominal distension, smooth gas discharge, stool is normal, and auscultation gurgling sound is normal.
Take a turn for the better：Without abdominal distension, there is exhaust, but feel powerless or not smooth, auscultation gurgling sound is normal.
It is invalid：Symptom is without improvement, and auscultation gurgling sound is still active.
4.2 results：Treatment group fully recovers 39, effective 10, invalid 2, total effective rate 96.1%；Control group recovery from illness 15
Example, effective 25, invalid 11, total effective rate 78.4%, two groups of total effective rates compare, statistically significant (the P ＜ of difference
0.05).8, recurrence rate 15.7% are recurred in follow-up after 6 months, treatment group；Control group recurs i6, recurs 31.4%, and two groups are answered
Hair rate compares, and difference is statistically significant (P ＜ 0.05).
Specific embodiment
With reference to specific embodiment, the present invention is described in further detail.But this should not be interpreted as the present invention
The scope of above-mentioned theme is only limitted to following embodiment, and all technologies realized based on present invention belong to model of the invention
Enclose.
Embodiment 1
A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction, is 15 grams of You Semen Agriophylli Squarrosis, terrible 7 grams of lid, pomelo flower 4
Gram, 6 grams of Taibai Lily Herb, 3 grams of bitter citrus immature flower, 10 grams of jasmine, 7 grams of silk tree, 25 grams of Momordica grosvenori, 10 grams of balloonflower root, 20 grams of kusamaki broad-leaved podocarpus seed and receptacle,
All 25 grams of drawing, 12 grams of scarlet swertia herb, 30 grams of caecum grass are made water decoction according to conventional Chinese medicine preparation technology, everyone daily 1 dose.
Embodiment 2
A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction, is 12 grams of You Semen Agriophylli Squarrosis, terrible 6 grams of lid, pomelo flower 3
Gram, 5 grams of Taibai Lily Herb, 2 grams of bitter citrus immature flower, 8 grams of jasmine, 6 grams of silk tree, 20 grams of Momordica grosvenori, 8 grams of balloonflower root, 15 grams of kusamaki broad-leaved podocarpus seed and receptacle, all
20 grams of drawing, 10 grams of scarlet swertia herb, 25 grams of caecum grass are made water decoction according to conventional Chinese medicine preparation technology, everyone daily 1 dose.
Embodiment 3
A kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction, is 9 grams of You Semen Agriophylli Squarrosis, terrible 5 grams of lid, pomelo flower 2
Gram, 4 grams of Taibai Lily Herb, 1 gram of bitter citrus immature flower, 6 grams of jasmine, 5 grams of silk tree, 15 grams of Momordica grosvenori, 6 grams of balloonflower root, 10 grams of kusamaki broad-leaved podocarpus seed and receptacle, all
15 grams of drawing, 8 grams of scarlet swertia herb, 20 grams of caecum grass are made water decoction according to conventional Chinese medicine preparation technology, everyone daily 1 dose.
Claims (3)
1. a kind of Chinese medicine composition for treating primary chronic intestinal pseudo obstruction, it is characterised in that by the raw material of following mass ratio
Medicine is made：
Semen Agriophylli Squarrosi 9-15 parts, ghost 5-7 parts, pomelo flower 2-4 parts, Taibai Lily Herb 4-6 parts, bitter citrus immature flower 1-3 parts, jasmine 6-10 parts, night of lid
Close and spend 5-7 parts, Momordica grosvenori 15-25 parts, balloonflower root 6-10 parts, kusamaki broad-leaved podocarpus seed and receptacle 10-20 parts, all 15-25 parts, scarlet swertia herb 8-12 of drawing
Part, 20-30 parts of caecum grass.
2. the Chinese medicine composition of primary chronic intestinal pseudo obstruction is treated as claimed in claim 1, it is characterised in that by following
The bulk drug of mass ratio is made：
12 parts of Semen Agriophylli Squarrosi, terrible 6 parts of lid, 3 parts of pomelo flower, 5 parts of Taibai Lily Herb, 2 parts of bitter citrus immature flower, 8 parts of jasmine, 6 parts of silk tree, Momordica grosvenori
20 parts, 8 parts of balloonflower root, 15 parts of kusamaki broad-leaved podocarpus seed and receptacle, all draw 20 parts, 10 parts of scarlet swertia herb, caecum grass 25 parts.
3. the preparation method of the Chinese medicine composition of primary chronic intestinal pseudo obstruction is treated as claimed in claim 1, and its feature exists
In by the traditional Chinese medicinal components of the mass ratio be prepared into water decoction, tablet, water-honeyed pill, capsule, powder, paste, oral liquid,
Granula.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109602759A (en) * | 2019-01-17 | 2019-04-12 | 广西医科大学 | The purposes of kusamaki broad-leaved podocarpus seed and receptacle polysaccharide |
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2016
- 2016-11-17 CN CN201611067928.7A patent/CN106728710A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 邱德凯等: "《消化病特色诊疗技术》", 31 January 2004, 科学技术文献出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109602759A (en) * | 2019-01-17 | 2019-04-12 | 广西医科大学 | The purposes of kusamaki broad-leaved podocarpus seed and receptacle polysaccharide |
| CN109602759B (en) * | 2019-01-17 | 2020-10-09 | 广西医科大学 | Application of podocarpus macrophyllus polysaccharide |
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Application publication date: 20170531 |