CN106727675A - A kind of calcium-replenishing soft capsule and preparation method thereof - Google Patents
A kind of calcium-replenishing soft capsule and preparation method thereof Download PDFInfo
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- CN106727675A CN106727675A CN201510819963.9A CN201510819963A CN106727675A CN 106727675 A CN106727675 A CN 106727675A CN 201510819963 A CN201510819963 A CN 201510819963A CN 106727675 A CN106727675 A CN 106727675A
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- capsule
- soft capsule
- calcium
- ball
- gelatin
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- 239000007901 soft capsule Substances 0.000 title claims abstract description 30
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 22
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 22
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims abstract description 22
- 108010010803 Gelatin Proteins 0.000 claims abstract description 18
- 239000002775 capsule Substances 0.000 claims abstract description 18
- 229920000159 gelatin Polymers 0.000 claims abstract description 18
- 239000008273 gelatin Substances 0.000 claims abstract description 18
- 235000019322 gelatine Nutrition 0.000 claims abstract description 18
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 18
- 235000013871 bee wax Nutrition 0.000 claims abstract description 17
- 239000012166 beeswax Substances 0.000 claims abstract description 17
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 11
- 235000011187 glycerol Nutrition 0.000 claims abstract description 11
- 239000008213 purified water Substances 0.000 claims abstract description 11
- 235000012424 soybean oil Nutrition 0.000 claims abstract description 11
- 239000003549 soybean oil Substances 0.000 claims abstract description 11
- 239000004408 titanium dioxide Substances 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000011782 vitamin Substances 0.000 claims abstract description 10
- 238000001914 filtration Methods 0.000 claims abstract description 6
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims abstract description 6
- 239000003292 glue Substances 0.000 claims description 22
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 18
- 238000003756 stirring Methods 0.000 claims description 12
- 238000005406 washing Methods 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 10
- WIGIZIANZCJQQY-UHFFFAOYSA-N 4-ethyl-3-methyl-N-[2-[4-[[[(4-methylcyclohexyl)amino]-oxomethyl]sulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCC(C)CC2)C=C1 WIGIZIANZCJQQY-UHFFFAOYSA-N 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 7
- 239000003921 oil Substances 0.000 claims description 7
- 235000019198 oils Nutrition 0.000 claims description 7
- 239000006187 pill Substances 0.000 claims description 7
- 238000004513 sizing Methods 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 5
- 230000008859 change Effects 0.000 claims description 3
- 150000001875 compounds Chemical class 0.000 claims description 3
- 235000011194 food seasoning agent Nutrition 0.000 claims description 3
- 238000000227 grinding Methods 0.000 claims description 3
- 239000006210 lotion Substances 0.000 claims description 3
- 238000002844 melting Methods 0.000 claims description 3
- 230000008018 melting Effects 0.000 claims description 3
- -1 polyethylene terephthalate Polymers 0.000 claims description 3
- 229920000139 polyethylene terephthalate Polymers 0.000 claims description 3
- 239000005020 polyethylene terephthalate Substances 0.000 claims description 3
- 239000001993 wax Substances 0.000 claims description 3
- 229940021056 vitamin d3 Drugs 0.000 claims description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 6
- 229910052791 calcium Inorganic materials 0.000 abstract description 6
- 239000011575 calcium Substances 0.000 abstract description 6
- 230000000694 effects Effects 0.000 abstract description 5
- 239000011647 vitamin D3 Substances 0.000 abstract description 4
- 229930003316 Vitamin D Natural products 0.000 abstract description 2
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 230000009469 supplementation Effects 0.000 abstract description 2
- 229940088594 vitamin Drugs 0.000 abstract description 2
- 229930003231 vitamin Natural products 0.000 abstract description 2
- 235000013343 vitamin Nutrition 0.000 abstract description 2
- 239000011710 vitamin D Substances 0.000 abstract description 2
- 235000019166 vitamin D Nutrition 0.000 abstract description 2
- 150000003710 vitamin D derivatives Chemical class 0.000 abstract description 2
- 229940046008 vitamin d Drugs 0.000 abstract description 2
- 150000003722 vitamin derivatives Chemical class 0.000 abstract description 2
- 239000008204 material by function Substances 0.000 description 4
- 206010006956 Calcium deficiency Diseases 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Inorganic Chemistry (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
A kind of calcium-replenishing soft capsule and preparation method thereof, it is characterised in that consist of the following components in percentage by weight：By the calcium carbonate of 100 mesh sieve net filtrations：38%-40%, vitamin D3：0.005%-0.009%, soybean oil：20%-25%, beeswax：2.5%-3.5%, glycerine：5%-8%, purified water：10%-15%, gelatin：10%-15%, titanium dioxide：0.03%-0.08%.The soft easy to carry, simple production process of the calcium-replenishing software, capsule is in good taste, the ratio of calcium meets the daily demand of people in good and capsule of taking effect, people can also be met daily to the demand of vitamin, be adapted to require supplementation with calcium and the crowd of vitamin D is used.
Description
Technical field
The present invention relates to a kind of field of health care food, especially a kind of calcium-replenishing soft capsule and preparation method thereof.
Background technology
Soft capsule is also known as flexible glue pill, oily functional materials, functional materials solution or functional materials suspension, pastel even functional materials can be quantified pressure injection and be encapsulated in glued membrane by soft capsule packaging, size, different seal capsule are formed, it is by oils or water-insoluble liquid or suspension without dissolution etc. are closed in a kind of preparation in capsule shells to gelatin thing.With excellent isolation light, oxygen function and good visual effect, and bioavilability it is high, content is accurate, uniformity good, good appearance the features such as, it is especially suitable for the packaging such as medicine, health products, difference in functionality is realized by adding different compositions in soft capsule, with the improvement of people ' s living standards, and dietary structure and living-pattern preservation, many problems are also brought, such as calcium deficiency, calcium deficiency shows as having a pain in the leg, leg is soft, knot；Weak, irritated, energy is not concentrated, easily tired；Partial eclipse, apocleisis；Decayed tooth, hypoplasia of tooth；The symptoms such as easy allergy, easy catching a cold, the medicine that in the market is replenished the calcium also has a lot, but side effect is big, and be not suitable for edible for a long time, the health food for enriching calccium of in the market there are problems that many, and not only effect of supplemented calcium is undesirable, poor taste and easily make one to produce dependence feeling.
The content of the invention
In view of the shortcomings of the prior art, the present invention provide a kind of low cost, mouthfeel effect it is good, calcium-replenishing soft capsule and preparation method thereof.
The technical scheme is that：A kind of calcium-replenishing soft capsule and preparation method thereof, it is characterised in that consist of the following components in percentage by weight：Calcium carbonate：38%-40%, vitamin D3（Every gram of vitamine D3 containing 1,000,000 more than IU）：0.005%-0.009%, soybean oil：20%-25%, beeswax：2.5%-3.5%, glycerine：5%-8%, purified water：10%-15%, gelatin：10%-15%, titanium dioxide：0.03%-0.08%.
According to described calcium-replenishing soft capsule, its preparation method is comprised the following steps：
1）, calcium carbonate and vitamine D3 are weighed according to recipe requirements；
2）, glycerine, purified water, gelatin, titanium dioxide are weighed according to formula, first glycerine and purified water are put into water-bath type glue tank, then will be changed after glue tank is put into heater and is heated to 60-65 DEG C, by gelatin and titanium dioxide being put into glue tank, and it is heated to 70-80 DEG C, stirring decocts 1.5-2h；
3）, rapidly will change after glue tank is put into and is evacuated to -006-0.08Mpa in vacuum machine, to changing glue tank in mixture be de-gassed bubble treatment；
4）, run through 100 mesh sieve net filtrations after, obtain capsule hide glue gelatin, and be incubated at a temperature of 55-65 DEG C standby；
5）, soybean oil and beeswax are weighed by formula, during soybean oil first put into batch can, and batch can be put into be heated to 70 DEG C in heater, put into beeswax and be cooled to 40 DEG C after stirring melting, obtain beeswax oil mixed liquor；
6）, by the vitamin d3 and calcium carbonate in step 1 sequentially add in the batch can of step 5 beeswax oil mixed liquor in, and by batch can be put into rotating speed be 50r/min mixer in stir 1h（Stirring 10min, stops 5min, is repeated 4 times）, blend compounds body mill grinding 2-3 times；
7）, batch can is put into rapidly in vacuum machine and is evacuated to -0.06-008Mpa, and bubble removing treatment is carried out to mixture, obtain capsule-core feed liquid；
8）, pelleting：Capsule-core feed liquid in capsule hide glue gelatin and step 7 in step 4 is suppressed into granulating ball by automatic encapsulating machine；
9）, sizing：Capsule and pill is put into rotating cage, and is 18 ~ 26 DEG C in room temperature, humidity is to shape 4h under conditions of 30% ~ 40%；
10）, wash ball：Soft capsule after sizing is put into soft capsule washing machine, is washed with 95% edible ethanol, and soft capsule invades ethanol completely, soft capsule washing machine is opened, the dissolubility bur such as the oily wax on soft capsule surface is washed away, ethanol washing lotion is released, drain, and the soft capsule after washing is divided in screen tray；
11）, dry：It is 24-28 DEG C that screen tray is put into temperature, and humidity dries indoor seasoning 20-24h for 20-30%'s；
12）, select：Manually the unqualified balls such as special-shaped ball, flat ball, bubble ball, thin-walled ball, cause ball not of uniform size are chosen；
13）, packaging：Qualified capsule and pill is fitted into polyethylene terephthalate bottle with automatic rotation bottling machine.
Beneficial effects of the present invention are：Easy to carry, simple production process, capsule are in good taste, the ratio of calcium meets the daily demand of people in good and capsule of taking effect, moreover it is possible to meet people daily to the demand of vitamin, be adapted to require supplementation with calcium and the crowd of vitamin D uses.
Specific embodiment
Specific embodiment of the invention is described further below：
Embodiment 1
By the calcium carbonate of 100 mesh sieve net filtrations：38%, vitamin D3（Every gram of vitamine D3 containing 1,000,000 more than IU）：0.005%, soybean oil：20% beeswax：2.5%, glycerine：5%, purified water：10%, gelatin：10%, titanium dioxide：0.03%.
Its preparation method is comprised the following steps：
1）, 100 mesh calcium carbonate and vitamine D3 are weighed according to recipe requirements；
2）, glycerine, purified water, gelatin, titanium dioxide are weighed according to formula, first glycerine and purified water are put into water-bath type glue tank, then will be changed after glue tank is put into heater and is heated to 60-65 DEG C, by gelatin and titanium dioxide being put into glue tank, and it is heated to 70-80 DEG C, stirring decocts 1.5-2h；
3）, rapidly will change after glue tank is put into and is evacuated to -006-0.08Mpa in vacuum machine, to changing glue tank in mixture be de-gassed bubble treatment；
4）, run through 100 mesh sieve net filtrations after, obtain capsule hide glue gelatin, and be incubated at a temperature of 55-65 DEG C standby；
5）, soybean oil and beeswax are weighed by formula, during soybean oil first put into batch can, and batch can be put into be heated to 70 DEG C in heater, put into beeswax and be cooled to 40 DEG C after stirring melting, obtain beeswax oil mixed liquor；
6）, by the vitamine D3 in step 1 and 100 mesh calcium carbonate sequentially add in the batch can of step 5 beeswax oil mixed liquor in, and by batch can be put into rotating speed be 50r/min mixer in stir 1h（Stirring 10min, stops 5min, is repeated 4 times）, blend compounds body mill grinding 2-3 times；
7）, batch can is put into rapidly in vacuum machine and is evacuated to -0.06-008Mpa, and bubble removing treatment is carried out to mixture, obtain capsule-core feed liquid；
8）, pelleting：Capsule-core feed liquid in capsule hide glue gelatin and step 7 in step 4 is pressed into 1.0g/, the grain ball that temperature is 18-26 DEG C, humidity is 30%-40% by automatic encapsulating machine；
9）, sizing：Capsule and pill is put into rotating cage, and is 18 ~ 26 DEG C in room temperature, humidity is to shape 4h under conditions of 30% ~ 40%；
10）, wash ball：Soft capsule after sizing is put into soft capsule washing machine, is washed with 95% edible ethanol, and soft capsule invades ethanol completely, soft capsule washing machine is opened, the dissolubility bur such as the oily wax on soft capsule surface is washed away, ethanol washing lotion is released, drain, and the soft capsule after washing is divided in screen tray；
11）, dry：It is 24-28 DEG C that screen tray is put into temperature, and humidity dries indoor seasoning 20-24h for 20-30%'s；
12）, select：Manually the unqualified balls such as special-shaped ball, flat ball, bubble ball, thin-walled ball, cause ball not of uniform size are chosen；
13）, packaging：Qualified capsule and pill is fitted into polyethylene terephthalate bottle with automatic rotation bottling machine, 60 every bottle.
Embodiment 2
By the calcium carbonate of 100 mesh sieve net filtrations：39%, vitamin D3（Every gram of vitamine D3 containing 1,000,000 more than IU）：0.009%, soybean oil：22%, beeswax：3.2%, glycerine：7%, purified water：14%, gelatin：14%, titanium dioxide： 0.06%.
Preparation method is with embodiment 1.
Merely illustrating the principles of the invention described in above-described embodiment and specification and most preferred embodiment; without departing from the spirit and scope of the present invention; various changes and modifications of the present invention are possible, and these changes and improvements all fall within the protetion scope of the claimed invention.
Claims (2)
1. a kind of calcium-replenishing soft capsule, it is characterised in that consist of the following components in percentage by weight：Calcium carbonate：38%-40%, vitamine D3：0.005%-0.009%, soybean oil：20%-25%, beeswax：2.5%-3.5%, glycerine：5%-8%, purified water：10%-15%, gelatin：10%-15%, titanium dioxide：0.03%-0.08%.
2. the preparation method of a kind of calcium-replenishing soft capsule according to claim 1, it is characterised in that comprise the following steps：
1）, calcium carbonate and vitamine D3 are weighed according to recipe requirements；
2）, glycerine, purified water, gelatin, titanium dioxide are weighed according to formula, first glycerine and purified water are put into water-bath type glue tank, then will be changed after glue tank is put into heater and is heated to 60-65 DEG C, by gelatin and titanium dioxide being put into glue tank, and it is heated to 70-80 DEG C, stirring decocts 1.5-2h；
3）, rapidly will change after glue tank is put into and is evacuated to -006-0.08Mpa in vacuum machine, to changing glue tank in mixture be de-gassed bubble treatment；
4）, run through 100 mesh sieve net filtrations after, obtain capsule hide glue gelatin, and be incubated at a temperature of 55-65 DEG C standby；
5）, soybean oil and beeswax are weighed by formula, during soybean oil first put into batch can, and batch can be put into be heated to 70 DEG C in heater, put into beeswax and be cooled to 40 DEG C after stirring melting, obtain beeswax oil mixed liquor；
6）, by the vitamin d3 and calcium carbonate in step 1 sequentially add in the batch can of step 5 beeswax oil mixed liquor in, and by batch can be put into rotating speed be 50r/min mixer in stir 1h（Stirring 10min, stops 5min, is repeated 4 times）, blend compounds body mill grinding 2-3 times；
7）, batch can is put into rapidly in vacuum machine and is evacuated to -0.06-008Mpa, and bubble removing treatment is carried out to mixture, obtain capsule-core feed liquid；
8）, pelleting：Capsule-core feed liquid in capsule hide glue gelatin and step 7 in step 4 is suppressed into granulating ball by automatic encapsulating machine；
9）, sizing：Capsule and pill is put into rotating cage, and is 18 ~ 26 DEG C in room temperature, humidity is to shape 4h under conditions of 30% ~ 40%；
10）, wash ball：Soft capsule after sizing is put into soft capsule washing machine, is washed with 95% edible ethanol, and soft capsule invades ethanol completely, soft capsule washing machine is opened, the dissolubility bur such as the oily wax on soft capsule surface is washed away, ethanol washing lotion is released, drain, and the soft capsule after washing is divided in screen tray；
11）, dry：It is 24-28 DEG C that screen tray is put into temperature, and humidity dries indoor seasoning 20-24h for 20-30%'s；
12）, select：Manually the unqualified balls such as special-shaped ball, flat ball, bubble ball, thin-walled ball, cause ball not of uniform size are chosen；
13）, packaging：Qualified capsule and pill is fitted into polyethylene terephthalate bottle with automatic rotation bottling machine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510819963.9A CN106727675A (en) | 2015-11-24 | 2015-11-24 | A kind of calcium-replenishing soft capsule and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510819963.9A CN106727675A (en) | 2015-11-24 | 2015-11-24 | A kind of calcium-replenishing soft capsule and preparation method thereof |
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| CN106727675A true CN106727675A (en) | 2017-05-31 |
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| CN201510819963.9A Pending CN106727675A (en) | 2015-11-24 | 2015-11-24 | A kind of calcium-replenishing soft capsule and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107343651A (en) * | 2017-06-22 | 2017-11-14 | 宜都宏济科技有限公司 | A kind of chewing type soft capsule replenished the calcium and preparation method thereof |
| CN108552535A (en) * | 2018-04-08 | 2018-09-21 | 广州纽优生物科技有限公司 | calcium soft capsule and preparation method |
| CN108567937A (en) * | 2018-07-19 | 2018-09-25 | 深圳市博奥生物科技有限公司 | One kind is replenished the calcium soft capsule and preparation method thereof |
| CN108936687A (en) * | 2018-08-08 | 2018-12-07 | 深圳极醇健康产业股份有限公司 | A kind of soft capsule and preparation method thereof of replenishing vitamins KD calcium |
| CN109662953A (en) * | 2019-02-18 | 2019-04-23 | 威海金思力生物科技股份有限公司 | A kind of vitamin D soft capsule and preparation method thereof |
| CN111617049A (en) * | 2020-06-22 | 2020-09-04 | 广东燕岭生命科技股份有限公司 | Novel preparation device and preparation process of vitamin D calcium supplement soft capsules |
| CN111685329A (en) * | 2020-06-22 | 2020-09-22 | 广东燕岭生命科技股份有限公司 | Processing formula of novel vitamin D calcium supplement soft capsule |
| CN113115954A (en) * | 2019-12-31 | 2021-07-16 | 北京司晨扬帆国际管理咨询有限公司 | Calcium vitamin D3Vitamin K2Health food and its preparation method |
| CN113244260A (en) * | 2021-04-15 | 2021-08-13 | 山东卫康生物医药科技有限公司 | Soft capsule for supplementing calcium, magnesium and vitamin D |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107343651A (en) * | 2017-06-22 | 2017-11-14 | 宜都宏济科技有限公司 | A kind of chewing type soft capsule replenished the calcium and preparation method thereof |
| CN108552535A (en) * | 2018-04-08 | 2018-09-21 | 广州纽优生物科技有限公司 | calcium soft capsule and preparation method |
| CN108567937A (en) * | 2018-07-19 | 2018-09-25 | 深圳市博奥生物科技有限公司 | One kind is replenished the calcium soft capsule and preparation method thereof |
| CN108936687A (en) * | 2018-08-08 | 2018-12-07 | 深圳极醇健康产业股份有限公司 | A kind of soft capsule and preparation method thereof of replenishing vitamins KD calcium |
| CN109662953A (en) * | 2019-02-18 | 2019-04-23 | 威海金思力生物科技股份有限公司 | A kind of vitamin D soft capsule and preparation method thereof |
| CN113115954A (en) * | 2019-12-31 | 2021-07-16 | 北京司晨扬帆国际管理咨询有限公司 | Calcium vitamin D3Vitamin K2Health food and its preparation method |
| CN111617049A (en) * | 2020-06-22 | 2020-09-04 | 广东燕岭生命科技股份有限公司 | Novel preparation device and preparation process of vitamin D calcium supplement soft capsules |
| CN111685329A (en) * | 2020-06-22 | 2020-09-22 | 广东燕岭生命科技股份有限公司 | Processing formula of novel vitamin D calcium supplement soft capsule |
| CN113244260A (en) * | 2021-04-15 | 2021-08-13 | 山东卫康生物医药科技有限公司 | Soft capsule for supplementing calcium, magnesium and vitamin D |
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