CN106727019A

CN106727019A - A kind of Chinese cassia tree shampoo and preparation method thereof

Info

Publication number: CN106727019A
Application number: CN201710014178.5A
Authority: CN
Inventors: 王娟; 余拓; 姚杭村
Original assignee: South China University of Technology SCUT
Current assignee: South China University of Technology SCUT
Priority date: 2017-01-09
Filing date: 2017-01-09
Publication date: 2017-05-31

Abstract

The invention discloses a kind of Chinese cassia tree shampoo and preparation method thereof.The Chinese cassia tree shampoo by mass percentage, including following component：Cassia gum hydroxypropyl-trimethyl ammonium chloride 1 8%, lauroyl methyl taurate 6 10%, cocounut oil acyl methyl taurate 5 8%; fatty acyl amine type tertiary amine 1 3%, trimethylglycine 1 2%, paratoluenesulfonic acid sodium salt 1 2.5%; disodium ethylene diamine tetraacetate 0.05 0.1%; polyoxyethylene carboxylate 1 5%, Rosmarinic acid 0.1 0.4%, arbor-vitae leaf volatile oil 1 4%; ginko leaves flavone 2 6%; tanshinone 1 5%, sodium chloride 0.5 1%, piroctone olamine salt 0.1 0.5%；Chinese cassia tree extract solution 2 7%, trisodium citrate 0.5 2%, NaOH 0.5 2%, balance of deionized water.Resist cold heat-resisting, anti-dandruff and Anti-hair loss ability of shampoo of the present invention is strong, and bacterio static itching-relieving.

Description

A kind of Chinese cassia tree shampoo and preparation method thereof

Technical field

The invention belongs to daily-use chemical industry technical field, and in particular to a kind of Chinese cassia tree shampoo and preparation method thereof.

Background technology

Shampoo be most commonly used hair and scalp basic nursing cosmetic product, it is necessary to have stronger hair care, protect color, Anti-hair loss, anti-dandruff and cleansing power, further need exist for certain antibacterial functions and aromatic odor.And existing shampoo is present Heat-resisting tolerance to cold is not strong, can seldom accomplish Anti-hair loss and preferable anti-dandruff, antibacterial and antipruritic effect.

Therefore, heat-resisting cold-resistant not strong for existing shampoo, Anti-hair loss, anti-dandruff, antibacterial and antipruritic scarce capacity problem are anxious A kind of new shampoo need to be developed, to solve the above problems.

Arbor-vitae leaf volatile oil, ginko leaves flavone, tanshinone and cassia gum hydroxypropyl-trimethyl ammonium chloride are added to shampoo In, strong and cold-resistant heat-resisting with hair care, anti-dandruff and Anti-hair loss, antipruritic ability, safety is gentle, it is adaptable to be grown up, and easily Degraded, substantially reduces the pollution to environment.Additionally, using Chinese cassia tree extract solution as preservative, not only having this shampoo good Bacterio static itching-relieving ability, moreover it is possible to increase the special aromatic odor of this shampoo, while Chinese cassia tree extract solution has preferable anticreep Hair effect.

The content of the invention

In order to overcome the deficiencies in the prior art, it is an object of the invention to provide a kind of Chinese cassia tree shampoo and its preparation side Method.

The purpose of the present invention is achieved through the following technical solutions.

A kind of Chinese cassia tree shampoo, by mass percentage, including following component：

A groups

Cassia gum hydroxypropyl-trimethyl ammonium chloride 1%-8%,

Deionized water surplus；

B groups

C groups

D groups

Chinese cassia tree extract solution 2%-7%；

E groups

Trisodium citrate 0.5%-2%,

NaOH 0.5%-2%.

Further, the trimethylglycine is replaced using olive oil 2%-5%.

Further, the trimethylglycine is replaced using collagen 2%-7%.

Further, the polyoxyethylene carboxylate is replaced using stearic acid sucrose ester 1%-4%.

Further, the piroctone olamine salt is replaced using ZPT 0.5%-2%.

Further, the piroctone olamine salt is replaced using salicylic acid 0.5%-2%.

Further, the extraction of the Chinese cassia tree extract solution comprises the following steps：

After cassia, basyleaves, Chinese cassia tree branch and FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are mixed, first dry to constant weight, then crush, eventually pass super Critical carbon dioxide is extracted or Subcritical water chromotagraphy, is separated, and obtains Chinese cassia tree extract solution.

Further, the mass ratio 1 of the cassia, basyleaves, Chinese cassia tree branch and FRUCTUS CINNAMOMI CASSIAE LMMA-TURI：(2-5)：(1-3)： (1-2), preferably 1:2:1:1 or 1:3:2:2 or 1:5:3:2.

Further, the material particular diameter after the crushing is in 0.5-5mm.

Further, the temperature that the supercritical carbon dioxide is extracted is 30-45 DEG C, and pressure is 25-40MPa, CO₂'s Flow is 20-35kg/h, and extraction time is 20min-80min.

Further, the temperature of the Subcritical water chromotagraphy is 110-140 DEG C, and pressure is 2-8MPa, and the time is 10- 40min, solid-liquid ratio is 1-4:10.

A kind of preparation method of described Chinese cassia tree shampoo, comprises the following steps：

(1) the cassia gum hydroxypropyl-trimethyl ammonium chloride in A groups is dissolved in deionized water, agitating heating；

(2) in each component in B groups being sequentially added into the solution that step (1) is obtained in order while stirring, and guarantor is heated Wen Hou, then natural cooling；

(3) when being cooled to 40-45 DEG C, each component in C groups is sequentially added in order, stir；Treat that solution is down to room Wen Hou, continuously adds the Chinese cassia tree extract solution in D groups, after stirring, adds each component regulation pH value in E groups, obtains the meat Osmanthus shampoo.

Further, in step (1), the temperature of the agitating heating is 40-45 DEG C, and the time is 10-20min.

Further, in step (2), the temperature of the heating and thermal insulation is 60-70 DEG C, and the time is 15-20min.

Further, the pH value is in 5.0-6.5.

Cassia gum hydroxypropyl-trimethyl ammonium chloride is natural derivative multifunctional polymer, and used as conditioner, it can improve Smooth, the anti-entanglement of this product, easily arrange and color development retentivity, it first added in deionized water and is heated to 40-45 DEG C, Dissolution time can not only be reduced, moreover it is possible to which appropriateness increases the denseness of product.

Arbor-vitae leaf volatile oil, ginko leaves flavone and tanshinone are all the main component extracted in natural plants, day It is right green, safety and Health, non-stimulated, as Anti-hair loss agent, with invigorate blood circulation, antibacterial, debris removing anticreep, strengthen hair follicle metabolism etc. Effect.

Raw material is mixed into cassia, basyleaves, Chinese cassia tree branch and FRUCTUS CINNAMOMI CASSIAE LMMA-TURI, is extracted using supercritical carbon dioxide or sub- Critical is extracted and obtains Chinese cassia tree extract solution, and Chinese cassia tree is extracted liquid energy and assigns product antibacterial, gently restrains skin, dredges brain network and rush Enter sanguimotor effect, and this product can be made to possess the peat-reek of Chinese cassia tree.

Compared with prior art, the invention has the advantages that and technique effect：

(1) of the invention compared with shampoo on the market, hair care, anti-dandruff and Anti-hair loss ability are strong, heat-resisting cold-resistant, Suitable for adult, and easily it is biodegradable, substantially reduces the pollution to environment；

(2) shampoo of the present invention not only with the ability of good bacterio static itching-relieving, goes back Chinese cassia tree extract solution as preservative The special aromatic odor of shampoo can be increased, while Chinese cassia tree extract solution has preferable Anti-hair loss effect.

Specific embodiment

Below in conjunction with example to it is of the invention implementation be described further, but it is of the invention implementation and protection be not limited to it is following Embodiment.

The product of the embodiment of the present invention is according in GBT 29679-2013 shampoos, hair cream and cosmetics health specification It is required that the method for inspection, carry out mercury, lead, arsenic, methyl alcohol, microorganism and go the inspection of sense organ project.

The test experiments of the present embodiment include：

1st, anti-dandruff experiment

According to where wait (2009)《The foundation and application study of the anti-dandruff effect detection evaluation method of shampoo》In test Method, 35 volunteers of selection, the wherein people of male 7, the people of women 28, the oldest person 48 years old, reckling 20 years old, average 34.9 ± 5.9 years old.

Experiment a few days ago not wash my hair, fixes two medical practitioner inspections, and dandruff most serious portion is chosen in the side of left and right two Position, all subjects use own control, to be informed in detail and hit exactly point left and right sides with scalp forehead hairline, and two are used respectively The different hair shampoo article of kind (it is required that first washing side with test shampoo, opposite side head is washed with control group shampoo again after flushing, Control group shampoo is random one kind selected from shampoo common on the market), once every other day, after 2 weeks, after 4 weeks it is each with Visit once, regularity in one's life is kept during experiment.

Experiment before and after 2 weeks, 4 Zhou Houjun carry out the culture of scalp chlosma and count clump count, comparative test is all around Both sides scalp chlosma every square centimeter falls counting number average, draws anti-dandruff experimental result.

Embodiment 1

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 2:1:After 1 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 0.5mm；Carried with supercritical carbon dioxide Take, be then peeled off removing cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI, obtain Chinese cassia tree extract solution；Supercritical carbon dioxide is carried The temperature for taking is 30 DEG C, and pressure is 25MPa, and the flow of carbon dioxide is 20kg/h, and extraction time is 80min；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 2%, arbor-vitae leaf volatile oil 1%, Ginko leaves flavone 2%, tanshinone 1%, cassia gum hydroxypropyl-trimethyl ammonium chloride 1%, lauroyl methyl taurate 6%, coconut palm Oleoyl methyl taurate 5%, fatty acyl amine type tertiary amine 2%, trimethylglycine 1%, paratoluenesulfonic acid sodium salt 1%, ethylenediamine Tetraacethyl disodium 0.1%, polyoxyethylene carboxylate 1%, Rosmarinic acid 0.1%, sodium chloride 0.5%, salicylic acid 1%, lemon Sour trisodium 0.5%, NaOH 2%, remaining is deionized water；

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 40 DEG C are heated to after 10min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, trimethylglycine, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, polyoxyethylene carboxylate, and 60 DEG C are heated to, 15min, then natural cooling is incubated；When temperature drops to 40 DEG C, Rosmarinic acid, cacumen biotae volatilization are sequentially added Oil, ginko leaves flavone, tanshinone, sodium chloride, salicylic acid, stir, and after solution is down to room temperature, continuously add Chinese cassia tree extraction Liquid；After stirring, pH value is adjusted to 6.5 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in table 1.

The examination and test of products result of 1 embodiment of table 1

As shown in Table 1, the Chinese cassia tree shampoo for being prepared by embodiment 1 has preferable bacteriostasis, and the heat-resisting and health that resists cold refers to Reference symbol is closed《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation the results are shown in Table 2.

Table 2 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 2, anti-dandruff effect of shampoo prepared by embodiment 1 is obvious, and effect is better than control group shampoo.

Embodiment 2

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 3:2:After 1 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 2mm；Extracted with supercritical carbon dioxide, It is then peeled off removing cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI, obtains Chinese cassia tree extract solution；What supercritical carbon dioxide was extracted Temperature is 45 DEG C, and pressure is 35MPa, and the flow of carbon dioxide is 30kg/h, and extraction time is 40min；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 7%, arbor-vitae leaf volatile oil 4%, Ginko leaves flavone 6%, tanshinone 5%, cassia gum hydroxypropyl-trimethyl ammonium chloride 6%, lauroyl methyl taurate 6%, coconut palm Oleoyl methyl taurate 7%, fatty acyl amine type tertiary amine 1%, trimethylglycine 1%, paratoluenesulfonic acid sodium salt 1%, ethylenediamine Tetraacethyl disodium 0.05%, stearic acid sucrose ester 1%, Rosmarinic acid 0.1%, sodium chloride 0.5%, piroctone olamine salt (OCT) 0.1%, trisodium citrate 1%, NaOH 0.5%, remaining is deionized water.

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 45 DEG C are heated to after 15min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, trimethylglycine, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, stearic acid sucrose ester, and heat To 65 DEG C, 15min, then natural cooling are incubated；When temperature drops to 45 DEG C, Rosmarinic acid, arbor-vitae leaf volatile oil, silver are sequentially added Apricot leaf flavones, tanshinone, sodium chloride, piroctone olamine salt, stir, and after solution is down to room temperature, continuously add meat Osmanthus extract solution；After stirring, pH value is adjusted to 6.0 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in table 3.

The examination and test of products result of 3 embodiment of table 2

As shown in Table 3, the Chinese cassia tree shampoo for being prepared by embodiment 2 has preferable bacteriostasis, and the heat-resisting and health that resists cold refers to Reference symbol is closed《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation is shown in Table 4.

Table 4 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 4, anti-dandruff effect of shampoo prepared by embodiment 2 is obvious, and effect is better than control group shampoo.

Embodiment 3

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 5:3:After 2 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 3mm；Extracted with supercritical carbon dioxide, It is then peeled off removing cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI, obtains Chinese cassia tree extract solution；What supercritical carbon dioxide was extracted Temperature is 40 DEG C, and pressure is 30MPa, and the flow of carbon dioxide is 25kg/h, and extraction time is 60min；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 5%, arbor-vitae leaf volatile oil 4%, Ginko leaves flavone 2%, tanshinone 1%, cassia gum hydroxypropyl-trimethyl ammonium chloride 8%, lauroyl methyl taurate 10%, coconut palm Oleoyl methyl taurate 8%, fatty acyl amine type tertiary amine 2%, olive oil 2%, paratoluenesulfonic acid sodium salt 1.5%, ethylenediamine tetrem Acid disodium 0.1%, stearic acid sucrose ester 3%, Rosmarinic acid 0.3%, sodium chloride 0.5%, salicylic acid 2%, trisodium citrate 2%, NaOH 0.5%, remaining is deionized water.

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 40 DEG C are heated to after 10min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, olive oil, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, stearic acid sucrose ester, and it is heated to 60 DEG C, it is incubated 20min, then natural cooling；When temperature drops to 40 DEG C, Rosmarinic acid, arbor-vitae leaf volatile oil, ginkgo leaf are sequentially added Flavones, tanshinone, sodium chloride, salicylic acid, stir, and after solution is down to room temperature, continuously add Chinese cassia tree extract solution；Stirring is equal After even, pH value is adjusted to 5.5 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in table 5.

The examination and test of products result of 5 embodiment of table 3

As shown in Table 5, the Chinese cassia tree shampoo for being prepared by example 3 has preferable bacteriostasis, and the heat-resisting and sanitary index that resists cold is accorded with Close《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation is shown in Table 6.

Table 6 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 6, anti-dandruff effect of shampoo prepared by embodiment 3 is obvious, and effect is better than control group shampoo.

Embodiment 4

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 2:1:After 1 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 2mm；Extracted with supercritical carbon dioxide, It is then peeled off removing cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI, obtains Chinese cassia tree extract solution；What supercritical carbon dioxide was extracted Temperature is 35 DEG C, and pressure is 40MPa, and the flow of carbon dioxide is 35kg/h, and extraction time is 20min；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 6%, arbor-vitae leaf volatile oil 3%, Ginko leaves flavone 6%, tanshinone 2%, cassia gum hydroxypropyl-trimethyl ammonium chloride 6%, lauroyl methyl taurate 7%, coconut palm Oleoyl methyl taurate 6%, fatty acyl amine type tertiary amine 3%, collagen 7%, paratoluenesulfonic acid sodium salt 2.5%, ethylenediamine tetraacetic Acetic acid disodium 0.05%, stearic acid sucrose ester 1%, Rosmarinic acid 0.2%, sodium chloride 1%, ZPT 1%, citric acid three Sodium 2%, NaOH 1%, remaining is deionized water.

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 40 DEG C are heated to after 10min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, collagen, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, stearic acid sucrose ester, and it is heated to 70 DEG C, it is incubated 20min, then natural cooling；When temperature drops to 40 DEG C, Rosmarinic acid, arbor-vitae leaf volatile oil, ginkgo leaf are sequentially added Flavones, tanshinone, sodium chloride, ZPT, stir, and after solution is down to room temperature, continuously add Chinese cassia tree extract solution；Stir After mixing uniformly, pH value is adjusted to 6.5 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in table 7.

The examination and test of products result of 7 embodiment of table 4

As shown in Table 7, the Chinese cassia tree shampoo for being prepared by example 4 has preferable bacteriostasis, and the heat-resisting and sanitary index that resists cold is accorded with Close《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation is shown in Table 8.

Table 8 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 8, anti-dandruff effect of shampoo prepared by embodiment 4 is obvious, and effect is better than control group shampoo.

Embodiment 5

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 5:3:After 2 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 1mm；With Subcritical water chromotagraphy, Ran Houfen From cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI is removed, Chinese cassia tree extract solution is obtained；The temperature of Subcritical water chromotagraphy is 140 DEG C, Pressure is 4MPa, and extraction time is 20min, and solid-liquid ratio is 1:10；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 5%, arbor-vitae leaf volatile oil 2%, Ginko leaves flavone 4%, tanshinone 5%, cassia gum hydroxypropyl-trimethyl ammonium chloride 7%, lauroyl methyl taurate 6%, coconut palm Oleoyl methyl taurate 5%, fatty acyl amine type tertiary amine 1%, collagen 4%, paratoluenesulfonic acid sodium salt 1%, ethylenediamine tetrem Acid disodium 0.1%, polyoxyethylene carboxylate 5%, Rosmarinic acid 0.4%, sodium chloride 0.5%, salicylic acid 1.5%, citric acid Trisodium 1%, NaOH 2%, remaining is deionized water.

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 45 DEG C are heated to after 10min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, collagen, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, stearic acid sucrose ester, and it is heated to 70 DEG C, it is incubated 20min, then natural cooling；When temperature drops to 45 DEG C, Rosmarinic acid, arbor-vitae leaf volatile oil, ginkgo leaf are sequentially added Flavones, tanshinone, sodium chloride, ZPT, stir, and after solution is down to room temperature, continuously add Chinese cassia tree extract solution；Stir After mixing uniformly, pH value is adjusted to 5.5 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in table 9.

The examination and test of products result of 9 embodiment of table 5

As shown in Table 9, the Chinese cassia tree shampoo for being prepared by example 5 has preferable bacteriostasis, and the heat-resisting and sanitary index that resists cold is accorded with Close《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation is shown in Table 10.

Table 10 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 10, anti-dandruff effect of shampoo prepared by embodiment 5 is obvious, and effect is better than control group shampoo.

Embodiment 6

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 2:1:After 1 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 3mm；With Subcritical water chromotagraphy, Ran Houfen From cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI is removed, Chinese cassia tree extract solution is obtained；The temperature of Subcritical water chromotagraphy is 110 DEG C, Pressure is 2MPa, and extraction time is 40min, and solid-liquid ratio is 2:10；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 6%, arbor-vitae leaf volatile oil 3%, Ginko leaves flavone 4%, tanshinone 4%, cassia gum hydroxypropyl-trimethyl ammonium chloride 8%, lauroyl methyl taurate 10%, coconut palm Oleoyl methyl taurate 5%, fatty acyl amine type tertiary amine 2%, trimethylglycine 2%, paratoluenesulfonic acid sodium salt 2.5%, second two Amine tetraacethyl disodium 0.1%, stearic acid sucrose ester 1%, Rosmarinic acid 0.1%, sodium chloride 1%, ZPT 2%, lemon Sour trisodium 2%, NaOH 1%, remaining is deionized water.

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 40 DEG C are heated to after 20min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, trimethylglycine, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, stearic acid sucrose ester, and heat To 65 DEG C, 15min, then natural cooling are incubated；When temperature drops to 40 DEG C, Rosmarinic acid, arbor-vitae leaf volatile oil, silver are sequentially added Apricot leaf flavones, tanshinone, sodium chloride, ZPT, stir, and after solution is down to room temperature, continuously add Chinese cassia tree extraction Liquid；After stirring, pH value is adjusted to 5.0 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in table 11.

The examination and test of products result of 11 embodiment of table 6

As shown in Table 11, the Chinese cassia tree shampoo for being prepared by embodiment 6 has preferable bacteriostasis, and the heat-resisting and health that resists cold refers to Reference symbol is closed《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation is shown in Table 12.

Table 12 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 12, anti-dandruff effect of shampoo prepared by embodiment 6 is obvious, and effect is better than control group shampoo.

Embodiment 7

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 5:3:After 2 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 2mm；With Subcritical water chromotagraphy, Ran Houfen From cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI is removed, Chinese cassia tree extract solution is obtained；The temperature of Subcritical water chromotagraphy is 120 DEG C, Pressure is 6MPa, and extraction time is 30min, and solid-liquid ratio is 3:10；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 7%, arbor-vitae leaf volatile oil 2%, Ginko leaves flavone 6%, tanshinone 3%, cassia gum hydroxypropyl-trimethyl ammonium chloride 7%, lauroyl methyl taurate 8%, coconut palm Oleoyl methyl taurate 8%, fatty acyl amine type tertiary amine 3%, collagen 5%, paratoluenesulfonic acid sodium salt 2%, ethylenediamine tetrem Acid disodium 0.05%, stearic acid sucrose ester 2%, Rosmarinic acid 0.2%, sodium chloride 1%, piroctone olamine salt (OCT) 0.5%, trisodium citrate 0.5%, NaOH 1.5%, remaining is deionized water.

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 45 DEG C are heated to after 15min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, collagen, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, stearic acid sucrose ester, and it is heated to 60 DEG C, it is incubated 20min, then natural cooling；When temperature drops to 45 DEG C, Rosmarinic acid, arbor-vitae leaf volatile oil, ginkgo leaf are sequentially added Flavones, tanshinone, sodium chloride, piroctone olamine salt (OCT), stir, and after solution is down to room temperature, continuously add meat Osmanthus extract solution；After stirring, pH value is adjusted to 6.5 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in table 13.

The examination and test of products result of 13 embodiment of table 7

As shown in Table 13, the Chinese cassia tree shampoo for being prepared by embodiment 7 has preferable bacteriostasis, and the heat-resisting and health that resists cold refers to Reference symbol is closed《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation is shown in Table 14.

Table 14 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 14, anti-dandruff effect of shampoo prepared by embodiment 7 is obvious, and effect is better than control group shampoo.

Embodiment 8

(1) preparation of cinnamon essential oil extract solution：Cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are taken, according to mass ratio 1: 3:2:After 2 ratio mixing, first dry to constant weight, then crush, raw material powder particle diameter is 3mm；With Subcritical water chromotagraphy, Ran Houfen From cassia, basyleaves, Chinese cassia tree branch, FRUCTUS CINNAMOMI CASSIAE LMMA-TURI is removed, Chinese cassia tree extract solution is obtained；The temperature of Subcritical water chromotagraphy is 130 DEG C, Pressure is 8MPa, and extraction time is 10min, and solid-liquid ratio is 4:10；

(2) Chinese cassia tree shampoo includes following components (mass percent)：Chinese cassia tree extract solution 6%, arbor-vitae leaf volatile oil 3%, Ginko leaves flavone 4%, tanshinone 5%, cassia gum hydroxypropyl-trimethyl ammonium chloride 6%, lauroyl methyl taurate 7%, coconut palm Oleoyl methyl taurate 6%, fatty acyl amine type tertiary amine 2%, olive oil 3%, paratoluenesulfonic acid sodium salt 2%, ethylenediamine tetra-acetic acid Disodium 0.1%, polyoxyethylene carboxylate 1%, Rosmarinic acid 0.1%, sodium chloride 1%, ZPT 2%, citric acid three Sodium 0.5%, NaOH 2%, remaining is deionized water.

(3) preparation of Chinese cassia tree shampoo：First cassia gum hydroxypropyl-trimethyl ammonium chloride is dissolved in deionized water, is stirred 40 DEG C are heated to after 20min；Then sequentially add while stirring lauroyl methyl taurate, cocounut oil acyl methyl taurate, Fatty acyl amine type tertiary amine, olive oil, paratoluenesulfonic acid sodium salt, disodium ethylene diamine tetraacetate, polyoxyethylene carboxylate, and be heated to 65 DEG C, it is incubated 20min, then natural cooling；When temperature drops to 40 DEG C, Rosmarinic acid, arbor-vitae leaf volatile oil, ginkgo are sequentially added Leaf flavones, tanshinone, sodium chloride, ZPT, stir, and after solution is down to room temperature, continuously add Chinese cassia tree extract solution； After stirring, pH value is adjusted to 6.0 with the aqueous solution of trisodium citrate and NaOH, obtain Chinese cassia tree shampoo.

The testing result of the Chinese cassia tree shampoo for obtaining is as shown in Table 15.

The examination and test of products result of 15 embodiment of table 8

As shown in Table 15, the Chinese cassia tree shampoo for being prepared by embodiment 8 has preferable bacteriostasis, and the heat-resisting and health that resists cold refers to Reference symbol is closed《Cosmetics specification》Regulation.

The anti-dandruff experimental result of the shampoo of preparation is shown in Table 16.

Table 16 is tested the scalp chlosma every square centimeter of both sides all around and is fallen counting number average

As shown in Table 16, anti-dandruff effect of shampoo prepared by embodiment 8 is obvious, and effect is better than control group shampoo.

2nd, Anti-hair loss performance test

According to Zeng Minghui (2013)《Compound root bark of shaggy-fruited dittany breast preventing and treating alopecia Study on mechanism》In method of testing, to implement Chinese cassia tree shampoo prepared by example 1~8 carries out Anti-hair loss performance test, is given birth to shampoo observation each group mouse hair on the 4,6,8,12nd (wherein control group uses physiological saline to situation long, and excipient group uses the emulsion for not adding shampoo, while soft using dexamethasone Cream carries out contrast experiment), given a mark by mouse hair growing state.

Marking requirement is as follows, does not grow, and hair removal section skin is in yellowish pink：0 point；Hair removal section skin gray：1 point；Hair removal section Skin is in black：2 points；Hair removal section skin is in black and has a little hair to grow：3 points.

Using the statistics softwares of SPSS 13.0, measurement data is represented with mean ± standard deviation, is checked using t, with P<0.05 For difference is statistically significant, the test result for obtaining is shown in Table 17.

The Anti-hair loss the performance test results of Chinese cassia tree shampoo prepared by 17 embodiment of table 1~8

Compare with excipient：*p<0.05, * * p<0.01.

As seen from Table 17, the Chinese cassia tree shampoo that prepared by embodiment 1~8 can promote the growth of normal mouse hair, with figuration Statistically significant (the P of agent group comparing difference<0.01)；And dexamethasone acetate ointment can significantly inhibit the life of normal mouse hair It is long, with the statistically significant (P of excipient group comparing difference<0.05).

3rd, antipruritic performance test

Mouse 100 is taken, body weight 12-22g, male and female half and half are randomly divided into 10 groups, every group 10；Respectively physiological saline Group, Chinese cassia tree shampoo group prepared by embodiment 1~8.

The mouse back leg big thigh vulcanized sodium of 6wt% loses hair or feathers, and smears sample after 24h at depilation, with distillation after 3min Water is cleaned up and dried, and once a day, continuous two days, after last dose 1h, is abraded at depilation with sand paper, is allowed to rubescent, with Not bleeding is degree, and area is about 2cm × 2cm, and 0.01wt% histamine phosphate liquid 0.05ml are added dropwise on wound face, hereafter every 3min, the concentration of histamine phosphate liquid increases 0.01wt%, is incremented by with this arithmetic progression, turns one's head to lick right metapedes every time by every mouse When the histamine phosphate total amount given be itch-threshold.

Antipruritic test result is as shown in table 18.

The antipruritic the performance test results of table 18

As shown in Table 18, the Chinese cassia tree shower cream that prepared by embodiment 1~8 has good antipruritic effect.

Claims

1. a kind of Chinese cassia tree shampoo, it is characterised in that by mass percentage, including following component：

A groups

Cassia gum hydroxypropyl-trimethyl ammonium chloride 1%-8%,

Deionized water surplus；

B groups

Lauroyl methyl taurate 6%-10%,

Cocounut oil acyl methyl taurate 5%-8%,

Fatty acyl amine type tertiary amine 1%-3%,

Trimethylglycine 1%-2%,

Paratoluenesulfonic acid sodium salt 1%-2.5%,

Disodium ethylene diamine tetraacetate 0.05%-0.1%,

Polyoxyethylene carboxylate 1%-5%；

C groups

Rosmarinic acid 0.1%-0.4%,

Arbor-vitae leaf volatile oil 1%-4%,

Ginko leaves flavone 2%-6%,

Tanshinone 1%-5%,

Sodium chloride 0.5%-1%,

Piroctone olamine salt 0.1%-0.5%；

D groups

Chinese cassia tree extract solution 2%-7%；

E groups

Trisodium citrate 0.5%-2%,

NaOH 0.5%-2%.

2. a kind of Chinese cassia tree shampoo according to claim 1, it is characterised in that the trimethylglycine uses olive oil 2%-5% or collagen 2%-7% replaces.

3. a kind of Chinese cassia tree shampoo according to claim 1, it is characterised in that the polyoxyethylene carboxylate is using hard Resin acid sucrose ester 1%-4% replaces.

4. a kind of Chinese cassia tree shampoo according to claim 1, it is characterised in that the piroctone olamine salt uses pyrrole Pyridine thioketones zinc 0.5%-2% or salicylic acid 0.5%-2% replace.

5. a kind of Chinese cassia tree shampoo according to claim 1, it is characterised in that the extraction of the Chinese cassia tree extract solution is included such as Lower step：

After cassia, basyleaves, Chinese cassia tree branch and FRUCTUS CINNAMOMI CASSIAE LMMA-TURI are mixed, first dry to constant weight, then crush, eventually pass overcritical Carbon dioxide draw or Subcritical water chromotagraphy, separate, and obtain Chinese cassia tree extract solution.

6. a kind of Chinese cassia tree shampoo according to claim 5, it is characterised in that the cassia, basyleaves, Chinese cassia tree branch With the mass ratio 1 of FRUCTUS CINNAMOMI CASSIAE LMMA-TURI：（2-5）：（1-3）：（1-2）；Material particular diameter after the crushing is in 0.5-5mm.

7. a kind of Chinese cassia tree shampoo according to claim 5, it is characterised in that the cassia, basyleaves, Chinese cassia tree branch It is 1 with the mass ratio of FRUCTUS CINNAMOMI CASSIAE LMMA-TURI:2:1:1 or 1:3:2:2 or 1:5:3:2.

8. a kind of Chinese cassia tree shampoo according to claim 5, it is characterised in that the temperature that the supercritical carbon dioxide is extracted It is 30-45 DEG C to spend, and pressure is 25-40MPa, CO₂Flow be 20-35kg/h, extraction time is 20min-80min；The Asia The temperature that critical is extracted is 110-140 DEG C, and pressure is 2-8MPa, and the time is 10-40min, and solid-liquid ratio is 1-4:10.

9. the preparation method of a kind of Chinese cassia tree shampoo described in any one of claim 1 ~ 8, it is characterised in that including following step Suddenly：

（1）Cassia gum hydroxypropyl-trimethyl ammonium chloride in A groups is dissolved in deionized water, is heated to after stirring 10-20min 40-45℃；

（2）The each component in B groups is sequentially added into step in order while stirring（1）In the solution for obtaining, and it is heated to 60-70 DEG C, after insulation 15-20min, then natural cooling；

（3）When being cooled to 40-45 DEG C, each component in C groups is sequentially added in order, stir；After solution is down to room temperature, The Chinese cassia tree extract solution in D groups is continuously added, after stirring, each component adjusts pH value in 5.0-6.5 in adding E groups, obtains institute State Chinese cassia tree shampoo.