CN106726961A - A kind of cleaning agent for mouth cavity and preparation method thereof - Google Patents
A kind of cleaning agent for mouth cavity and preparation method thereof Download PDFInfo
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- CN106726961A CN106726961A CN201611210663.1A CN201611210663A CN106726961A CN 106726961 A CN106726961 A CN 106726961A CN 201611210663 A CN201611210663 A CN 201611210663A CN 106726961 A CN106726961 A CN 106726961A
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- cleaning agent
- mouth cavity
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- chinese medicine
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention belongs to daily chemical product field, and in particular to a kind of cleaning agent for mouth cavity and preparation method thereof.The cleaning agent for mouth cavity that the present invention is provided includes following components and its percentage by weight:1 3% surfactant, 6 12% acids, 1 5% carbohydrate, 15 25% Chinese medicine extracts, 1 3% preservative and 52 76% deionized waters.The cleaning agent for mouth cavity that the present invention is provided, except halitosis effect is good, smell is pleasant, and side effect non-stimulated to human body, disinfection effect is significantly, safe and reliable.Meanwhile, the cleaning agent for mouth cavity that the present invention is provided has certain booster action to promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, ascending the clear and descending the turbid, nourishing the blood and yin.
Description
Technical field
The invention belongs to daily chemical product field, and in particular to a kind of cleaning agent for mouth cavity and preparation method thereof.
Background technology
" bread is the staff of life, and food is with tooth as first ".Oral health state is the mirror for reflecting life and health quality.People
Health care to tooth does not cause enough attention.Among the people still have the saying of " toothache is not disease ", and has " missing in many understanding
Area ".Oral hygiene focus on control bacterial plaque, eliminate dirt and swill, strengthen physiological stimulation, make oral cavity and tooth jaw system
System has a good environment for cleaning health, so as to play its physiological function, safeguards oral health, oral cavity usually health except morning
Outside evening brushes teeth, in the last few years, the cleaning agent for mouth cavity liquid for using is more, and cleaning agent for mouth cavity category is numerous present on current market
It is many, but its bactericidal and bacteriostatic effect and its except halitosis effect is unsatisfactory.
Chinese patent application 201510725237.0 discloses a kind of cleaning agent for mouth cavity, puckery containing tea extraction and persimmon, system
The standby cleaning agent for mouth cavity for obtaining can be provided satisfactorily except halitosis effect, and tea extraction are puckery with natural virtue with persimmon
Perfume (or spice), smell is pleasant when using, but its removing taste effect is unsatisfactory.
Chinese patent application 2015480046813.2 discloses one kind and can for a long time keep bactericidal effect and inhibit
The liquid oral cleaning agent of the use electrolysis water of metal protection, the liquid oral cleaning agent is for just containing oxidation-reduction potential
Electrolysis water, menthol, anionic surfactant and water-miscible organic solvent and pH for the liquid oral of 6-8 it is clear
Clean dose, but its bactericidal effect is unsatisfactory.
The content of the invention
Be to solve problems of the prior art, the invention provides a kind of cleaning agent for mouth cavity, including following components and
Its percentage by weight:
1-3% surfactants, 6-12% acids, 1-5% carbohydrates, 15-25% Chinese medicine extracts, 1-3% preservatives
With 52-76% deionized waters.
Further, the cleaning agent for mouth cavity is made up of following components and its percentage by weight:
2% surfactant, 8% acid, 3% carbohydrate, 20% Chinese medicine extract, 2% preservative and 65% deionization
Water.
Further, the surfactant is by dodecyl sodium sulfate, Tea Saponin and dodecyldimethylammonium hydroxide inner salt
By weight 1:3:1 composition.Tea Saponin is purchased from Hunan Lang Lin biological products Co., Ltd.
Further, the acid be selected from citric acid, tartaric acid and malic acid in one or more.
Further, the carbohydrate be selected from fructose, glucose, sucrose and sorbierite in one or more.
Further, the component and parts by weight of the Chinese medicine extract are:By 3-5 portions of green tea, 2-4 portions of peppermint, 1-3 parts
Chrysanthemum, 2-4 portion of honeysuckle, 3-5 parts when ginseng, the 5-7 parts of red sage root and 4-6 parts of ginkgo leaf;Its preparation method is:Said components are pressed it
Parts by weight are weighed, and segment is put into frying pan the water for being blended into 4 times of gross weight number, and after being heated to boiling, constant temperature decocts 4h again
Afterwards, cease fire, after cooling, remove slag and take juice, the liquid for leaving as Chinese medicine extract.
Further, it is characterised in that the component and parts by weight of the Chinese medicine extract be:By 4 portions of green tea, 3 parts thin
Lotus, 2 parts of chrysanthemums, 3 portions of honeysuckles, 4 parts when ginseng, 6 parts of reds sage root and 5 parts of ginkgo leaves.
Further, the preservative be selected from potassium sorbate, sorbierite and Sodium Benzoate in one or more.
Meanwhile, present invention also offers a kind of preparation method of cleaning agent for mouth cavity, its step is as follows:
S1 adds deionized water in agitator tank, is heated to 70-80 DEG C, adds surfactant and carbohydrate, until all
Dissolving;
S2, by the agitator tank in acid and preservative addition step S1, continues after above-mentioned steps S1 stirs
Stirring;
Chinese medicine extract is heated to 80 DEG C by S3, in the agitator tank for then pouring into immediately in step S2 while hot, after stirring
It is even, natural cooling, it is 7.0 to adjust pH, is obtained final product.
The component of the Chinese medicine extract in the cleaning agent for mouth cavity that the present invention is provided:Green tea have arousing brain, raising spirit, fatigue-relieving,
The effects such as anti-aging, anti-inflammation and sterilization;Peppermint have fresh breath, antisepsis and sterilization, stomach invigorating, it is aid digestion the effects such as;Chrysanthemum has clear
The heart is tasty and refreshing, clear liver and improve vision, detoxicating, relieving inflammation the effects such as;Honeysuckle have anti-inflammatory, protect liver, it is antitumor the effects such as;When ginseng have tonifying Qi,
The effects such as invigorating the spleen, hypotensive;The effects such as red sage root has promoting blood circulation and removing blood stasis, relieving pain of dysmenorrhea, reduces blood viscousness;Ginkgo leaf has to be reduced
The effects such as blood cholesterol levels, step-down, reduction blood viscousness.Compatibility of the present invention is reasonable, science, and each component cooperates with seven bactericidals
Effect, can preferably remove halitosis, while can stimulate circulation, to reducing blood pressure, promoting blood circulation and removing blood stasis, nourishing the blood and yin has necessarily
Booster action.
Compared with prior art, the cleaning agent for mouth cavity that the present invention is provided, has the advantage that:
(1) cleaning agent for mouth cavity that the present invention is provided, except halitosis effect is good, smell is pleasant, and side effect non-stimulated to human body;
(2) cleaning agent for mouth cavity that the present invention is provided, has functions that bactericidal, anti-inflammatory;
(3) cleaning agent for mouth cavity that the present invention is provided has necessarily to promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain, ascending the clear and descending the turbid, nourishing the blood and yin
Booster action.
Specific embodiment
The present invention is described in further details below by specific embodiment, these embodiments are only used for the mesh of illustration
, it is in no way intended to limit protection scope of the present invention.
Embodiment 1-3, comparative example 1-3
In table 1,3 specific embodiments of cleaning agent for mouth cavity provided by the present invention and the component of comparative example 1-3 are listed
And its percentage by weight.
The embodiment of table 1 and comparative example component and its percentage by weight
Comparative example 1 is that surfactant is by dodecyl sodium sulfate, Tea Saponin and dodecane with the difference of embodiment 2
Base dimethyl betaine is by weight 1:1:1 composition.
Comparative example 2 is, without addition green tea in Chinese medicine extract, to increase the consumption of peppermint with the difference of embodiment 2.
Comparative example 3 is, without addition chrysanthemum in Chinese medicine extract, to increase the consumption of peppermint with the difference of embodiment 2.
The preparation method of the cleaning agent for mouth cavity of embodiment 1:
S1 adds deionized water in agitator tank, and heating stirring adds surfactant and carbohydrate, until all dissolvings;
S2, by the agitator tank in acid and preservative addition step S1, continues after above-mentioned steps S1 stirs
Stirring;
Chinese medicine extract is heated to 80 DEG C by S3, in the agitator tank for then pouring into immediately in step S2 while hot, after stirring
After even, natural cooling, it is 7.0 to adjust pH, is obtained final product.
The preparation method of the cleaning agent for mouth cavity of embodiment 2-3 and comparative example 1-3 is similar to Example 1.
Test example one, biocidal property evaluation
1. test material:Cleaning agent for mouth cavity and commercial oral cleaning agent prepared by embodiment 1-3, comparative example 1-3.
2. subjects:International standard bacterial strain, streptococcus mutans (S.mutansIngbritt, the blood of streptococcus mutans race
Clear type c) and streptococcus sobrinus (S.Sobrinus6715, serotype g).
3. content of the test:By bacteria test, i.e., in the Trypsin Induced soybean broth containing 1% sucrose
(TSB) Anaerobic culturel (CO280%, N210%, H210%) in, is surveyed respectively using liquid/agar dilution extracorporeal bacteria inhibitor test
Fixed each cleaning agent for mouth cavity is to two kinds of streptococcic minimum inhibitory concentrations and minimum bactericidal concentration.
4. result of the test:The minimum inhibitory concentration and minimum bactericidal concentration of bacteria test the results are shown in Table 2.
The cleaning agent for mouth cavity restraining and sterilizing bacteria measure of merit table of table 2
Note:* p < 0.05 are compared with comparative example 1;* compares p < 0.01 with comparative example 1;▲Compare p < with comparative example 2
0.05;▲▲Compare p < 0.01 with comparative example 2;●Compare p < 0.05 with comparative example 3;Compare p < with commercial oral cleaning agent
0.05;Compare p < 0.01 with commercial oral cleaning agent.
Known by table 2, compared with commercial oral cleaning agent, restraining and sterilizing bacteria ability has aobvious cleaning agent for mouth cavity prepared by the present invention
Write sex differernce.And the restraining and sterilizing bacteria ability of cleaning agent for mouth cavity prepared by comparative example 1-3 is than oral cavity prepared by embodiment of the present invention 1-3
The effect of cleaning agent is poor, illustrates Tea Saponin, green tea and the chrysanthemum of present invention offer and can be compounded with other components, has cooperateed with antibacterial
Sterilized effect.
Test example two, sensory evaluation is tested
(1) the cleaning effect experiment of smoke
1 test material:Cleaning agent for mouth cavity and commercial oral cleaning agent prepared by embodiment 1-3, comparative example 1-3.
2. subjects:140 subjects, age distribution is in 20-50 Sui, male.
3. content of the test:Subject is divided into 7 groups, it is used embodiment 1-3, comparative example 1-3 systems respectively after inhaling 1 cigarette
Standby cleaning agent for mouth cavity and commercial oral cleaning agent, to being commented using being compared afterwards therewith before cleaning agent for mouth cavity and carry out sense organ
Point.Scoring benchmark is as follows:2 points:There is no smoke after use completely and smell is pleasant;1 point:Somewhat there is smoke after use:0 point:Make
Any improvement is not obtained with rear oral peculiar smell.
4. result of the test:Scoring to the cleaning effect of smoke is shown in Table 3.
The cleaning agent for mouth cavity of table 3 removes grade form to smoke
Known by table 3, effect of the cleaning effect than commercially available cleaning agent fond of food that is not salty of cleaning agent for mouth cavity prepared by the present invention to smoke
It is good.And cleaning agent for mouth cavity prepared by comparative example 1-3 to the cleaning effect of smoke than oral cleaning prepared by embodiment of the present invention 1-3
The effect of agent is poor, illustrate compatibility of the present invention rationally, science, each component cooperate with clean smoke effect.
(2) garlicky cleaning effect experiment
1 test material:Cleaning agent for mouth cavity and commercial oral cleaning agent prepared by embodiment 1-3, comparative example 1-3.
2 subjects:140 subjects, at 20-50 Sui, men and women half and half for age distribution.
3. content of the test:Subject is divided into 7 groups, it is used embodiment 1-3, comparative example 1-3 respectively after chewing garlic
The cleaning agent for mouth cavity and commercial oral cleaning agent of preparation, to using being compared afterwards therewith before cleaning agent for mouth cavity and carry out sense organ
Scoring.Scoring benchmark is as follows:2 points:There is no smoke after use completely and smell is pleasant;1 point:Somewhat there is peculiar garlic smell after use;0
Point:Any improvement is not obtained using rear oral peculiar smell.
4. result of the test:Scoring to garlicky cleaning effect is shown in Table 4.
The cleaning agent for mouth cavity of table 4 is to garlicky removing grade form
Known by table 4, the effect of cleaning agent for mouth cavity prepared by the present invention to garlicky cleaning effect than commercial oral cleaning agent
It is good.And cleaning agent for mouth cavity prepared by comparative example 1-3 to garlicky cleaning effect than oral cleaning prepared by embodiment of the present invention 1-3
The effect of agent is poor, illustrate compatibility of the present invention rationally, science, each component cooperate with and cleaned garlicky effect.
By cleaning agent for mouth cavity of the invention have satisfactorily remove halitosis effect, and green tea, chrysanthemum, honeysuckle,
Peppermint have it is natural it is fragrant with it is salubrious, smell is pleasant when using.Meanwhile, the cleaning agent for mouth cavity that the present invention is provided is to promoting blood circulationization
The stasis of blood, promoting qi circulation and relieving pain, ascending the clear and descending the turbid, nourishing the blood and yin have certain booster action.
Claims (9)
1. a kind of cleaning agent for mouth cavity, it is characterised in that including following components and its percentage by weight:
1-3% surfactants, 6-12% acids, 1-5% carbohydrates, 15-25% Chinese medicine extracts, 1-3% preservatives and 52-
76% deionized water.
2. cleaning agent for mouth cavity according to claim 1, it is characterised in that be made up of following components and its percentage by weight:
2% surfactant, 8% acid, 3% carbohydrate, 20% Chinese medicine extract, 2% preservative and 65% deionized water.
3. cleaning agent for mouth cavity according to claim 1 and 2, it is characterised in that the surfactant is by dodecyl sulphur
Sour sodium, Tea Saponin and dodecyldimethylammonium hydroxide inner salt are by weight 1:3:1 composition.
4. cleaning agent for mouth cavity according to claim 1 and 2, it is characterised in that the acid is selected from citric acid, tartaric acid
With one or more in malic acid.
5. cleaning agent for mouth cavity according to claim 1 and 2, it is characterised in that the carbohydrate is selected from fructose, glucose, sugarcane
Sugar and sorbierite in one or more.
6. cleaning agent for mouth cavity according to claim 1 and 2, it is characterised in that the component and weight of the Chinese medicine extract
Number is:By 3-5 portions of green tea, 2-4 portions of peppermint, 1-3 parts of chrysanthemum, 2-4 portions of honeysuckle, 3-5 parts when ginseng, the 5-7 parts of red sage root and 4-6 parts
Ginkgo leaf.
7. cleaning agent for mouth cavity according to claim 6, it is characterised in that the component and parts by weight of the Chinese medicine extract
For:By 4 portions of green tea, 3 portions of peppermints, 2 parts of chrysanthemums, 3 portions of honeysuckles, 4 parts when ginseng, 6 parts of reds sage root and 5 parts of ginkgo leaves.
8. cleaning agent for mouth cavity according to claim 1 and 2, it is characterised in that the preservative is selected from potassium sorbate, sorb
One or more in alcohol and Sodium Benzoate.
9. according to the preparation method of any described cleaning agent for mouth cavity of claim 1-8, it is characterised in that comprise the following steps:
S1 adds deionized water in agitator tank, is heated to 70-80 DEG C, adds surfactant and carbohydrate, until all dissolvings;
S2, by the agitator tank in acid and preservative addition step S1, continues to stir after above-mentioned steps S1 stirs;
Chinese medicine extract is heated to 80 DEG C by S3, uniform after stirring in the agitator tank for then pouring into immediately in step S2 while hot, from
So cooling, it is 7.0 to adjust pH, is obtained final product.
Priority Applications (1)
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CN201611210663.1A CN106726961A (en) | 2016-12-24 | 2016-12-24 | A kind of cleaning agent for mouth cavity and preparation method thereof |
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CN201611210663.1A CN106726961A (en) | 2016-12-24 | 2016-12-24 | A kind of cleaning agent for mouth cavity and preparation method thereof |
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CN201611210663.1A Withdrawn CN106726961A (en) | 2016-12-24 | 2016-12-24 | A kind of cleaning agent for mouth cavity and preparation method thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108498400A (en) * | 2018-05-23 | 2018-09-07 | 安徽广生堂生物科技有限公司 | The formula of one Plant Extracts mix preparation and its method for making cleaning agent for mouth cavity |
CN109248099A (en) * | 2017-07-12 | 2019-01-22 | 北京甲护生物科技有限公司 | A kind of stable high oxidation electrolyzed-oxidizing water sterilization creme |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN102988192A (en) * | 2012-11-23 | 2013-03-27 | 广州市科玮生物技术有限公司 | Chlorophyll mouth wash and preparation method thereof |
CN104997667A (en) * | 2015-07-01 | 2015-10-28 | 南阳市汇博生物技术有限公司 | Multifunctional antibacterial mouthwash and preparation method thereof |
CN105106043A (en) * | 2015-07-16 | 2015-12-02 | 山东省分析测试中心 | Peony flower-containing anti-inflammation and deodorization fragrant mouthwash and preparation method thereof |
CN105326683A (en) * | 2015-10-30 | 2016-02-17 | 付锐涵 | Oral cavity cleaner |
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2016
- 2016-12-24 CN CN201611210663.1A patent/CN106726961A/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102988192A (en) * | 2012-11-23 | 2013-03-27 | 广州市科玮生物技术有限公司 | Chlorophyll mouth wash and preparation method thereof |
CN104997667A (en) * | 2015-07-01 | 2015-10-28 | 南阳市汇博生物技术有限公司 | Multifunctional antibacterial mouthwash and preparation method thereof |
CN105106043A (en) * | 2015-07-16 | 2015-12-02 | 山东省分析测试中心 | Peony flower-containing anti-inflammation and deodorization fragrant mouthwash and preparation method thereof |
CN105326683A (en) * | 2015-10-30 | 2016-02-17 | 付锐涵 | Oral cavity cleaner |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109248099A (en) * | 2017-07-12 | 2019-01-22 | 北京甲护生物科技有限公司 | A kind of stable high oxidation electrolyzed-oxidizing water sterilization creme |
CN108498400A (en) * | 2018-05-23 | 2018-09-07 | 安徽广生堂生物科技有限公司 | The formula of one Plant Extracts mix preparation and its method for making cleaning agent for mouth cavity |
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