CN106726892A - A kind of frosted facial washing milk of gentle oil control and acne removal and preparation method thereof - Google Patents
A kind of frosted facial washing milk of gentle oil control and acne removal and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
Abstract
The invention discloses a kind of frosted facial washing milk of gentle oil control and acne removal and preparation method thereof.Mildy wash of the present invention has used the surfactant and various natural products and derivative of amino acid structure, including plant abrasive particle, the root of kudzu vine and ginkgo leaf Chinese herb compound, phytosphingosine and aurantiamarin mother liquor, does not stimulate gently.Mildy wash of the present invention uses plant abrasive particle, and is carrying out rounding treatment to plant abrasive particle with special flow and technique using preceding, being sanded with by way of classified filtering, controls its diameter at 10 100 μm.Inventive formulation uses Chinese herb compound extract for four target spots in grease and acne mechanism of production, can be control effectively from source, obtained Chinese herb compound is safe, gentle and effective, can accomplish to control the generation of face's grease and the occurred level of acne simultaneously.
Description
Technical field
The invention belongs to daily chemicals field, and in particular to a kind of frosted facial washing milk of gentle oil control and acne removal and its preparation
Method.
Background technology
With the continuous improvement of living standard, people wash one's face the requirement also more and more higher of product, and mildy wash can be effectively
The grease and scurf of face are removed, makes us feeling salubrious comfortable；At present, using liquid or paste and bulk more than in the market
Face wash products, use these face wash products more and are made face wash products with petrochemical materials, and these raw materials include：Surfactant
Such as fatty alcohol polyoxyethylene ether sulfate (AES), alkanolamide, skin sense conditioner such as high molecular polymer, mineral oil, vegetable oil
Deng.In addition to surfactants, the material for being mainly used in degreasing exfoliating includes some abrasive materials, such as nylon is micro-
Ball, calcium carbonate microspheres etc..Additionally, for removing acne, used in the disclosed formula of some patents Chinese herbal medicine extract with
And some antibiotic etc..
Research and innovation and production to existing mildy wash, easy-to-use and salubrious sense is brought to consumer, but these grind
Study carefully and there is also some problems with product：One is a large amount of chemical raw materials for having used petrochemical industry to synthesize of some mildy wash, such as AES,
It inevitably brings the accessory substances such as dioxanes into during synthesis, except may to skin produce it is a certain degree of stimulation and
Damage, also as dioxanes there is a possibility that there is carcinogenic.Two is to add help in some mildy wash to dispel grease and angle
The abrasive particle of matter, such as nylon micro-sphere, calcium carbonate microspheres.The addition of abrasive material is dispelled to grease really and cutin has been dispelled
Help, but because to not careful enough in the treatment of abrasive material, some abrasive materials such as calcium carbonate particle etc., because not having
By rounding technique, it is easily caused during washing one's face and excessive wear is caused to consumer's cuticula, so as to destroy skin barrier, makes
Into red swelling of the skin, there is the increase of inflammation or even drying period transepidermal water loss amount.Although nylon micro-sphere is smaller to skin damage,
Because being difficult for its degraded, is gradually abandoned in recent years by American-European big shot skin care item company, and for management organization of European Union makes laws
Disabling；Three is that the mildy wash of some oil control and acne removals has used many Chinese herbal and crude drugs preparationses or compound, but often effect is invalidated, machine
Reason is hard to say, is intended only as increasing selling point and being added among mildy wash, tends not to really be effectively accomplished oil-control
The using effect of anti-acne.Four is that mildy wash well uses sense organ for consumer, has often used many petrochemical industries to synthesize
Grease (such as dimethyl siloxane), the use of these greases may cause consumer face oil and fat accumulation, cause fat granule
Generation equally likely possibility.
The content of the invention
It is an object of the invention to overcome above-mentioned deficiency, there is provided a kind of frosted facial washing milk of gentle oil control and acne removal and its preparation
Method.
The technical solution used in the present invention is：A kind of frosted facial washing milk, percentage, by following component group
Into：
A phase materials：
B phase materials：
Sodium methyl cocoyl taurate 1.0-3.0%
C phase materials：
D phase materials：
Preferably, described frosted facial washing milk, percentage is made up of following component：
A phase materials：
B phase materials：
Sodium methyl cocoyl taurate 1.0-2.0%
C phase materials：
D phase materials：
Preferably, described frosted facial washing milk, percentage is made up of following component：
A phase materials：
B phase materials：
Sodium methyl cocoyl taurate 1.0-2.0%
C phase materials：
D phase materials：
Preferably, the weight ratio of the root of kudzu vine and ginkgo leaf is (1-4) in the root of kudzu vine and ginkgo leaf Chinese herb compound:(4-1), it has
Effect composition is the alcohol extracting thing of the root of kudzu vine and ginkgo leaf.
Preferably, the weight ratio of the root of kudzu vine and ginkgo leaf is (1-3) in the root of kudzu vine and ginkgo leaf Chinese herb compound:(2-1), it has
Effect composition is the alcohol extracting thing of the root of kudzu vine and ginkgo leaf.
Preferably, the root of kudzu vine and ginkgo leaf are weighed according to said ratio, is smashed with pulverizer.Take 10 times of roots of kudzu vine and silver
The closed immersion herbal prescription of edible alcohol of the 75% of apricot leaf weight, is placed in low temperature shady place 5-10d, and period stirs two daily
It is secondary.Soak is taken out into 500 mesh sieve net filtrations, filtered fluid is taken and is added Rotary Evaporators, 45 DEG C of rotary evaporations to evaporate 90% wine
Essence and water, finally obtain extracts of Chinese herbal medicine, obtain 100% herbal prescription medicinal extract, are the root of kudzu vine and ginkgo leaf Chinese herb compound.
Preferably, phytosphingosine and aurantiamarin compound are to mix phytosphingosine and aurantiamarin in mass ratio 1: 4, its
Active ingredient is the alcohol extracting thing of phytosphingosine and aurantiamarin.
Preferably, phytosphingosine and aurantiamarin in mass ratio 1: 4 are mixed, takes the ethanol solution of 5g plus 50%-70%
To 100g, the preferably ethanol solution of 50%-60% is dissolved, and obtains 5% solution, standby.
Preferably, plant abrasive particle obtains plant powder by bleaching and rounding treatment, its a diameter of 10-
100μm。
Preferably, plant powder includes walnut shell powder, tangerine peel powder, almug powder and/or white incense wood powder.
Preferably, walnut shell powder in plant powder：Tangerine peel powder：The weight ratio of almug powder or white incense wood powder is 1：1：1,2：
1：1.5,3：2：1.5.
A kind of preparation method of frosted facial washing milk, comprises the following steps：
1) pure water of A phases, EDETATE SODIUM, cocounut oil acyl glycine potassium, C8-C1 alkyl glucosides, glycerine are added into main cooker, heating is stirred
Mix to after 75~80 DEG C, add polyethylene glycol stearate diester, dodecanamide propyl hydroxy sulfo lycine, pearlescent flake, stratiform silicon
Hydrochlorate dispersion liquid, is incubated 75~80 DEG C and stirs 10 minutes, after material body completes dissolving, then starts cooling；
2) when temperature is down to below 45 DEG C, B phase sodium methyl cocoyl taurates, stirring are added；
3) acrylic acid esters co-polymer is dissipated with C phase pure water moisture, is stirred, it is standby；
4) under 200-400r/min stirrings, by step 3) the pre- solution of acrylic acid esters co-polymer that obtains is added to step 2)
To solution in, it is then uniform under 600-800r/min stirrings, add C phase leftover materials, and D phase materials.Stir
Afterwards, can discharging packaging after standing 2 hours.
Preferably, the amount of C phases pure water is five times of acrylic acid esters co-polymer.
The beneficial effects of the invention are as follows：
Mildy wash of the present invention has used surfactant and various natural products and derivative (including the plant of amino acid structure
Abrasive particle, the root of kudzu vine and ginkgo leaf Chinese herb compound, phytosphingosine and aurantiamarin compound), do not stimulate gently.Amino acid surface
Activating agent is new surfactant, and its synthesis condition is gentle, environment-friendly, and the toxic accessory substance such as dioxanes is not produced.
Its moderate performance in actual product, excitant is extremely low, adapt to for cuticula than relatively thin skin be also easy to produce sensitivity face.
In addition inventive formulation also uses various natural products and derivative.
Mildy wash of the present invention is using plant abrasive particle (mainly including walnut shell powder, tangerine peel powder, santal wood powder, white incense wood
Powder etc.), and rounding treatment is being carried out to plant abrasive particle with special flow and technique using preceding, by being sanded and being classified
The mode of filter, controls its diameter at 10-100 μm.These plant abrasive particles, and can temperature can effectively adsorb grease using process
It is purged with to facial cuticula, so as to have good improvement to the grease and corresponding clogging of pores that produce acne.Comprising
Plant abrasive particle in mildy wash possesses the effectiveness of certain oil-control secretion and microorganism infection, and plant frosted grain
Son is affine to environment, can smoothly be degraded in natural environment.
Inventive formulation uses Chinese herb compound extract for four target spots in grease and acne mechanism of production, including
1st, androgen and stosterone are converted into the suppression of the 5α-reductase of high activity dihydrotestosterone；2nd, hair follicle and sebaceous glands androgen
The Reverse transcriptase of acceptor；3rd, the acne microbial growth with propionibacterium acnes as representative is suppressed；4th, to inflammation that some are produced
The generation of inflammation factor such as leukotriene, IL-2 etc. is suppressed.The inventive method is control effectively from source, obtains medium-height grass
Medicine compound is safe, gentle and effective, can accomplish to control the generation of face's grease and the occurred level of acne simultaneously.
Dairy products of washing one's face of the invention abandons the grease such as dimethyl siloxane of commercial synthesis, or some animal fats such as silk floss
Sheep oil etc..These commercial synthesis or the thick and heavy animal fat of comparing, although can cause the skin sense of mildy wash improves, but may be because of it
Remain in face and cause consumer to produce the generation of fat granule or more acne.The present invention only adds day in dairy products of washing one's face
The vegetable fat of right small-molecular-weight, it is ensured that mildy wash it is salubrious, after use not to face skin produce burden so that injure.
Specific embodiment
Plant abrasive particle raw material uses walnut shell powder, tangerine peel powder and almug powder, or substitutes almug with white incense wood powder
Powder.
Its preparation method comprises the following steps：First by corresponding plant abrasive particle according to certain rank, 200 mesh sieves are crossed
Net, then using the hydrogen peroxide of 10%-20%, 8-12, preferably 10-11 is adjusted to using the NaOH of 1mol/L by the pH of hydrogen peroxide.
By abrasive particle in being put into hydrogen peroxide, stirring at low speed 1-2h, then sieved bleaching compound with 400 eye mesh screens, with 10 times of amounts
Pure water is rinsed, and then the abrasive particle of bleaching is put into the 15L horizontal sand mills containing 2mm zirconium oxide beads, sets sand mill
Rotating speed is 100-500rpm, preferably 200-300rpm, is circulated 5 times, rounding treatment is carried out to plant abrasive particle, by being classified
The mode of filter, controls its diameter between 10-100 μm, preferably 50-100 μm, is placed in 80 DEG C of environment ventilation dry for standby.
By bleaching, rounding technique, these plant abrasive particles have diameter similar, close to the form of ball, are using
Process can effectively adsorb grease, and leniently facial cuticula can be purged, and consumer is rinsed in natural environment after washing one's face
In can conveniently degrade, environment protecting is favourable.
The root of kudzu vine and ginkgo leaf are weighed for 1: 4-4: 1 according to the weight ratio of the root of kudzu vine and ginkgo leaf, are smashed with pulverizer.Take
The closed immersion herbal prescription of edible alcohol of the 75% of 10 times of roots of kudzu vine and ginkgo leaf weight, is placed in low temperature shady place 5-10d,
Period stirring daily is twice.Soak is taken out into 500 mesh sieve net filtrations, filtered fluid is taken and is added Rotary Evaporators, 45 DEG C of rotations are steamed
Hair, evaporates 90% alcohol and water, finally obtains extracts of Chinese herbal medicine, obtains 100% herbal prescription medicinal extract, standby.
Phytosphingosine and aurantiamarin in mass ratio 1: 4 are mixed, the ethanol solution of 5g plus 50%-70% is taken to 100g,
It is preferred that the ethanol solution of 50%-60% is dissolved, 5% solution is obtained, it is standby.With reference to embodiment, this is expanded on further
The content of the invention.
Embodiment
The mildy wash formula of the present invention of table 1 (percentage by weight, altogether 100%)
According to the mildy wash that preparation embodiment is formulated table 1 Suo Shi, preparation method is as follows：
1) pure water of A phases, EDTA-2 sodium, cocounut oil acyl glycine potassium, C8-C1 alkyl glucosides, glycerine are added into main cooker, heating is stirred
Mix to after 75~80 DEG C, add DM638 (polyethylene glycol stearate diester), dodecanamide propyl hydroxy sulfo lycine, pearlescent flake,
ROMOL HE (phyllosilicate dispersion liquid), are incubated 75~80 DEG C and stir 10 minutes, after material body completes dissolving, then start drop
Temperature.
2) when temperature is down to below 45 DEG C, B phase cocounut oil acyl methyl taurine sodium, stirring are added；
3) with C phase pure water dispersion acrylic lipin polymers, stir, it is standby；
4) under 200-400r/min stirrings, by step 3) the pre- solution of acrylic acid esters co-polymer that obtains is added to step 2)
To solution in, it is then uniform under 600-800r/min stirrings, add C phase leftover materials, and D phase materials.Stir
Afterwards, can discharging packaging after standing 2 hours.
Effect detection is carried out to above-described embodiment.
First, the excitant of chick chorioallantoic membrane experiment detection mildy wash
With reference to cosmetics eye irritation/corrosive chick chorioallantoic membrane experiment of inspection and quarantining for import/export professional standard issue
Standard, using reaction time method, instar chicken embryo on the 9th is carried out according to egg inspection, in eggshell surface mark air chamber position；Sawed with dentistry
The curved tweezer of tooth peels off the eggshell part of tape label, the white egg film of exposure.Drawing appropriate 0.9%NaCl solution with suction pipe moistens egg film
Afterwards, 0.9%NaCl solution is poured out.Careful tweezers remove inner membrance, it is ensured that tunica vasculose is not damaged.The quilt of 0.3mL is drawn respectively
Test agent, is added dropwise on CAM surface, starts bleeding, blood vessel dissolving, the time of blood coagulation, period record occur in record 5min
Shadow is simultaneously taken pictures, and every kind of mildy wash does 6 parallel laboratory tests.With 0.9%NaCl solution as negative control, 0.3%NaOH is positive right
According to material control on the basis of, 1% fatty alcohol-ether sodium sulfate salt mixture (ASV).
Use the standards of grading of reaction time method to stimulate point system, formula is as follows：
Formula：IS=(301-secH) × 5/300+ (301-secL) × 7/300+ (301-secC) × 9/300
In formula：
The average time that bleeding takes place is observed on secH (bleeding time)-CAM films, unit is the second (s)；
Observed on secL (blood vessel melts the time)-CAM films and the average time that blood vessel melts takes place, unit is the second (s)；
The average time for starting blood coagulation occur is observed on secC (clotting time)-CAM films, unit is the second (s)；
IS numerical value according to the form below (table 2) scope according to calculating is classified to tested material eye irritation.
Table 2 stimulates appraisal result evaluation
| Stimulate scoring | Stimulate classification |
| IS<1 | It is nonirritant |
| 1≤IS<5 | Slight stimulation |
| 5≤IS<9 | Moderate excitant |
| IS≥9 | Severe excitant |
The cosmetics eye irritation issued according to inspection and quarantining for import/export professional standard/corrosive chick chorioallantoic membrane experiment
Standard, by bleeding, blood coagulation, blood vessel dissolving be divided into following grade.
Bleeding：
1) without bleeding；
2) hyporrhea：Rarely seen thin vessels bleeding and a small amount of bleeding (such as 0.5%ASV acts on 5min)；
3) moderate bleeding：Thin vessels and big angiorrbagia, and have obvious blood outflow (such as 1%ASV acts on 5min)；
4) severe bleeding：Almost all of angiorrbagia, and have substantial amounts of blood outflow (such as 5%ASV acts on 5min).
Blood coagulation：
1) without blood coagulation；
2) slight blood coagulation：Ink vessel transfusing or (and) slight blood coagulation outside blood vessel (such as 0.2% NaOH acts on 5min)；
3) moderate blood coagulation：Ink vessel transfusing or (and) the outer moderate blood coagulation of blood vessel (such as 0.3% NaOH acts on 5min)；
4) severe blood coagulation：Ink vessel transfusing or (and) the outer severe blood coagulation of blood vessel (such as 0.5% NaOH acts on 5min).
Blood vessel dissolves：
1) dissolved without blood vessel；
2) slight blood vessel dissolving：Only thin vessels dissolving (0.5%ASV acts on 5min)；
3) moderate blood vessel dissolving：Thin vessels and big blood vessel dissolving (1%ASV acts on 5min)；
4) severe blood vessel dissolving：Big blood vessel and whole vascular trees all dissolve (5%ASV acts on 5min).
According to the method described above to embodiment obtain mildy wash and AES systems mildy wash and without plant extracts
Amino acid mildy wash contrasted, experimental result is shown in Table 3.
The chicken embryo stimulation test grade form of each embodiment of table 3
As known from Table 3, it is (general to stimulate average mark between 6-10, and moderate with mildy wash usually using petrochemical industry system AES systems
Excitant and severe excitant) and without the amino acid mildy wash (general stimulation average mark is between 5-8) of plant extracts,
And in the present invention, each embodiment mildy wash combined by amino acid surfactant Chinese herb compound, its excitant is substantially dropped
Low, score value can reach the effect of gentle face cleaning between 4.4-5.6.
2nd, moistening effect and oil-control effect
The volunteer using mildy wash of the present invention is carried out to monitor within 4 hours using skin oil and fat moisture content alkalinity acidity tester, assessment
Volunteer's face moisture and fat content.Ask 30 volunteer men and women half and half, the age at 15-35 Sui, in temperature 25 ± 2
DEG C, the confined space of humidity 50 ± 5% is washed with 25 ± 2 DEG C of clear water plus mildy wash of the present invention (embodiment 1) (each 5g)
Face, afterwards from 0 hour to 4 hours, skin of face of survey in every 60 minutes (taking the test of forehead, chin and both sides cheek respectively)
Water content and oil content, take 30 is worth following table for each person.Test result is shown in Table 4.
Table 4 uses the average moisture content and fat content of volunteer's skin of face after mildy wash
As known from Table 4, there are a lasting hold mode, 4 to the water content of volunteer's skin of face using mildy wash of the present invention
Moisture content of skin state is still slightly better than the state do not washed one's face after hour.Meanwhile, mildy wash can significantly reduce face at the initial stage of washing one's face
Oil content, and can be controlled within 4 hours and reduce the secretion of grease.
The mildy wash of embodiment 1-9 is optimal with embodiment 1 in the effect of moistening effect and oil-control effect, next to that implementing
Example 2 (is 20.3% using 4 hours moisture content of skin, skin oil content is 6.7%) and 3 (are using 4 hours moisture content of skin
19.5%, skin oil content is for 6.8%), the effect of embodiment 1-3 is better than embodiment 4-9.Because skin can be influenceed in embodiment 1
The amount of the plant abrasive particle of barrier is moderate, controls the root of kudzu vine of fat secretion and the Chinese herbal medicine compound of ginkgo leaf to match optimal,
The content of phytosphingosine and aurantiamarin is also optimal, so embodiment moisturizing and oil-control best results.Wherein, plant abrasive particle
Adding proportion is 4%, walnut shell powder：Tangerine peel powder：The optimum proportioning of almug powder (or white incense wood powder) is 3：2：1.5, the root of kudzu vine and
Ginkgo leaf compound addition is 6%, and optimum proportioning is 3: 2.The addition of phytosphingosine and aurantiamarin compound (5%) is 3%-
5%.
The plant abrasive particle addition and phytosphingosine and aurantiamarin mother liquor addition of embodiment 4,5,6 are slightly smaller,
Have impact on the effect of oil-control moisturizing.Embodiment 7,8,9, the addition of plant abrasive particle is slightly larger, although phytosphingosine and orange
Skin glycosides mother liquor is moderate, but plant abrasive particle can excessively influence skin barrier function, the transepidermal water loss rate of skin is become big, grease
Secretion is in increase trend.
3rd, anti-acne effect：
Mildy wash of the present invention (embodiment 2) and commercially available non-amino acid mildy wash are carried out into practical effect assessment by volunteer,
Select acne symptom in I, II phase, the age, 80 volunteers of men and women half and half were randomly divided into two groups, treatment group somewhere between 15-35 Sui
45, after using 1,2,4 weeks, by dermatologist observation evaluation skin of face and acne conditions；Control group 35, makes
With the common mildy wash of commercially available non-amino acid surfactant.
The using effect of table 5 is evaluated
| Group | Number of cases | It is effective | It is progressive | It is invalid | Total effective rate |
| Embodiment 1 | 45 | 5 | 25 | 15 | 66.7% |
| Control | 35 | 1 | 5 | 29 | 17.1% |
Clinical observation on the therapeutic effect concrete outcome is carried out by dermatologist and is shown in Table 5.Treatment group totally 72, wherein curing 5, cures
Rate is 11.1%；It it is effectively 30, total effective rate is 66.7%.Control group totally 35, wherein curing 1, cure rate is
2.9%；It it is effectively 6, total effective rate is 17.1%.Anti-acne facial cleanser of the invention exists in using effect than common mildy wash
Significant difference.
Comparative example 1
Plant abrasive particle in being formulated using the nylon micro-sphere abrasive particle alternate embodiment 1 through rounding, other components are with real
Example 1 is applied, comparative example 1 is obtained and is formulated.Carry out above-mentioned irritant experiment and moistening effect and oil-control effect experiment.Draw comparative example 1
The stimulation of formula is equally divided into 5.1, is moderate excitant, and the excitant to skin is bigger than embodiment 1.Water content and fat content
It is shown in Table 6.
Table 6 uses volunteer's skin average moisture content and fat content after comparative example 1
As shown in Table 6：The moisturizing of comparative example 1 and oil-control effect are slightly poorer than embodiment 1.
Further, since nylon micro-sphere abrasive particle is synthesis, and the abrasive particle of plant origin of the present invention is not only natural,
And environmental protection, twice laid.
Comparative example 2
With embodiment 2, difference is that plant abrasive particle does not carry out rounding treatment, obtains comparative example 2 and is formulated.Carry out
State irritant experiment and moistening effect and oil-control effect experiment.Show that the stimulation of the formula of comparative example 2 is equally divided into 5.5, be moderate
Stimulate.Moistening effect and oil-control effect the results are shown in Table 7.
Table 7 uses volunteer's skin average moisture content and fat content after comparative example 2
As shown in Table 7, moisturizing and oil-control effect are poorer than embodiment 2.Plant of the plant particles without rounding with respect to rounding treatment
For particle, the excitant to skin can be relatively larger.Although plant abrasive particle also plays the role of oil resistant moisturizing, by
Comprehending at no rounding causes its destruction skin barrier function, transepidermal water loss rate is become big, and fat secretion is in increase trend.
Comparative example 3
The ratio of the Chinese herb compound of the root of kudzu vine and ginkgo leaf is 0, and other components obtain comparative example 3 and be formulated with embodiment 1.Carry out
Above-mentioned irritant experiment and moistening effect and oil-control effect experiment.Show that the stimulation of the formula of comparative example 3 is equally divided into 4.6, be light
Degree stimulates.Moistening effect and oil-control effect the results are shown in Table 8.
Table 8 uses volunteer's skin average moisture content and fat content after comparative example 3
As shown in Table 8, with embodiment 1 quite, oil-control effect is poorer than embodiment 1, because in the root of kudzu vine and ginkgo leaf for moistening effect
There are the active ingredient for suppressing to produce grease, when there is no the root of kudzu vine and ginkgo leaf Chinese herb compound in formula, grease in herbal composition
Secretion can aggravate, but moisture content of skin influence can be ignored.For excitant, because influenceing irritating principal element
It is whether plant abrasive particle is processed by rounding, the plant abrasive particle of comparative example 3 and embodiment 1 is processed by rounding
, so excitant is more or less the same.
Comparative example 4
The content of phytosphingosine and aurantiamarin mother liquor is 0, and other components obtain comparative example 4 and be formulated with embodiment 1.Carry out
State irritant experiment and moistening effect and oil-control effect experiment.Show that the stimulation of the formula of comparative example 4 is equally divided into 4.7, be slight
Stimulate.Moistening effect and oil-control effect the results are shown in Table 9.
Table 9 uses volunteer's skin average moisture content and fat content after comparative example 4
As shown in Table 9, with embodiment 1 quite, oil-control effect is poorer than embodiment 1, because phytosphingosine and orange peel for moistening effect
Glycosides is 5α-reductase inhibitor, can be little from the secretion of Sources controlling grease, the water content influence on skin.For excitant,
Because influenceing irritating principal element to be whether plant abrasive particle is processed by rounding, the plant of comparative example 4 and embodiment 1
Abrasive particle is processed by rounding, so excitant is more or less the same.
Above-described embodiment is the present invention preferably implementation method, but embodiments of the present invention are not by above-described embodiment
Limitation, it is other it is any without departing from Spirit Essence of the invention and the change, modification, replacement made under principle, combine, simplification,
Equivalent substitute mode is should be, is included within protection scope of the present invention.
Claims (9)
1. a kind of frosted facial washing milk, percentage, are made up of following component：
A phase materials：
Pure water surplus, EDTA disodium 0.1-0.15%, cocounut oil acyl glycine potassium 10.0-30.0%, C8-C1 alkyl glucoside
10.0-20.0%, glycerine 1.0-3.0%, polyethylene glycol stearate diester 0.15-0.25%, dodecanamide propyl hydroxyl sulfobetaines
Alkali 2.0-9.0%, pearlescent flake 1.0-3.0%, phyllosilicate dispersion liquid 3.0-6.0%；
B phase materials：
Sodium methyl cocoyl taurate 1.0-3.0%；
C phase materials：
Pure water 20-30%, acrylic acid esters co-polymer 4.0-6.0%, DMDMH 0.2-0.5%, essence 0.2-0.5%；
D phase materials：
Glycine betaine 1.0-5.0%, plant abrasive particle 1.0-8.0%, the root of kudzu vine and ginkgo leaf Chinese herb compound 1.0-10.0%, plant
Thing sphingol and aurantiamarin compound 1.0-15.0%.
2. frosted facial washing milk according to claim 1, it is characterised in that：Percentage, is made up of following component：
A phase materials：
Pure water surplus, EDTA disodium 0.1-0.12%, cocounut oil acyl glycine potassium 15.0-30.0%, C8-C1 alkyl glucoside
12.0-18.0%, glycerine 1.5-2.5%, polyethylene glycol stearate diester 0.15-0.22%, dodecanamide propyl hydroxy sulfo lycine
3.0-8.0%, pearlescent flake 1.5-2.5%, phyllosilicate dispersion liquid 3.0-5.0%；
B phase materials：
Sodium methyl cocoyl taurate 1.0-2.0%；
C phase materials：
Pure water 22.0-28.0%, acrylic acid esters co-polymer 4.5-5.5%, DMDM hydantoins 0.2-0.4%, essence 0.2-
0.4%；
D phase materials：
Glycine betaine 1.0-3.0%, plant abrasive particle 1.0-6.0%, the root of kudzu vine and ginkgo leaf Chinese herb compound 2.0-8.0%, plant
Thing sphingol and aurantiamarin compound 2.0-10.0%.
3. frosted facial washing milk according to claim 1, it is characterised in that：Percentage, is made up of following component：
A phase materials：
Pure water surplus, EDTA disodium 0.1-0.12%, cocounut oil acyl glycine potassium 16.0-28.0%, C8-C1 alkyl glucoside
13.0-16.0%, glycerine 1.5-2.5%, polyethylene glycol stearate diester 0.15-0.18%, dodecanamide propyl hydroxyl sulfobetaines
Alkali 4.0-7.0%, pearlescent flake 1.5-2.5%, phyllosilicate dispersion liquid 3.5-4.5%；
B phase materials：
Sodium methyl cocoyl taurate 1.0-2.0%；
C phase materials：
Pure water 25.0-30.0%, acrylic acid esters co-polymer 5.0-6.0%, DMDM hydantoins 0.25-0.35%, essence
0.2-0.3%；
D phase materials：
Glycine betaine 1.0-3.0%, plant abrasive particle 2.0-5.0%, the root of kudzu vine and ginkgo leaf Chinese herb compound 3.0-8.0%, plant
Sphingol and aurantiamarin compound 3.0-8.0%.
4. frosted facial washing milk according to claim 1, it is characterised in that：In the root of kudzu vine and ginkgo leaf Chinese herb compound the root of kudzu vine and
The weight ratio of ginkgo leaf is（1-4）:（4-1）, its active ingredient is the alcohol extracting thing of the root of kudzu vine and ginkgo leaf.
5. frosted facial washing milk according to claim 4, it is characterised in that：In the root of kudzu vine and ginkgo leaf Chinese herb compound the root of kudzu vine and
The weight ratio of ginkgo leaf is（1-3）:（2-1）, its active ingredient is the alcohol extracting thing of the root of kudzu vine and ginkgo leaf.
6. frosted facial washing milk according to claim 1, it is characterised in that：Phytosphingosine and aurantiamarin compound are by plant
Sphingol and aurantiamarin in mass ratio 1:4 mixing, its active ingredient is the alcohol extracting thing of phytosphingosine and aurantiamarin.
7. frosted facial washing milk according to claim 1, it is characterised in that：Plant abrasive particle is by floating by plant powder
The treatment of white and rounding, obtains its a diameter of 10-100 μm.
8. frosted facial washing milk according to claim 7, it is characterised in that：Plant powder includes walnut shell powder, tangerine peel powder, wingceltis
Perfume tree powder and/or white incense wood powder.
9. a kind of preparation method of frosted facial washing milk, it is characterised in that：Comprise the following steps：
1) pure water of A phases, EDTA disodiums, cocounut oil acyl glycine potassium, C8-C1 alkyl glucosides, glycerine are added into main cooker, heating
Stir to after 75~80 DEG C, add polyethylene glycol stearate diester, dodecanamide propyl hydroxy sulfo lycine, pearlescent flake, stratiform
Silicate dispersion liquid, is incubated 75~80 DEG C and stirs 10 minutes, after material body completes dissolving, then starts cooling；
2) when temperature is down to below 45 DEG C, B phase sodium methyl cocoyl taurates, stirring are added；
3) with C phase pure water dispersion acrylic lipin polymers, stir, it is standby；
4) under 200-400r/min stirrings, by step 3）The pre- solution of acrylic acid esters co-polymer for obtaining is added to step 2）
To solution in, it is then uniform under 600-800r/min stirrings, add C phase leftover materials, and D phase materials to stir
Afterwards, can discharging packaging after standing 2 hours；Wherein frosted facial washing milk each component is as described in claim any one of 1-8.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107485582A (en) * | 2017-08-18 | 2017-12-19 | 苏州莱奥生物技术有限公司 | A kind of frosted oil control facial cleanser |
| CN111494279A (en) * | 2020-05-07 | 2020-08-07 | 广东柏俐臣生物科技有限公司 | Cleaning cosmetic and preparation method thereof |
| CN112494381A (en) * | 2020-11-18 | 2021-03-16 | 美佳亚太投资有限公司 | Shaddock white capsule microparticle and preparation method and application thereof |
| CN113398051A (en) * | 2020-10-12 | 2021-09-17 | 中华全国供销合作总社南京野生植物综合利用研究所 | Plant combined extract for removing mites and acnes as well as preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257521A (en) * | 2014-10-22 | 2015-01-07 | 广东幸美化妆品股份有限公司 | Facial cleanser without irritation to eyes and preparation method thereof |
| CN105832572A (en) * | 2016-04-07 | 2016-08-10 | 广州宏度精细化工有限公司 | Amino acid facial cleanser and preparation method thereof |
| CN105997768A (en) * | 2016-07-29 | 2016-10-12 | 济宁医学院 | Mild moistening amino acid facial cleanser |
-
2016
- 2016-12-05 CN CN201611102764.7A patent/CN106726892B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104257521A (en) * | 2014-10-22 | 2015-01-07 | 广东幸美化妆品股份有限公司 | Facial cleanser without irritation to eyes and preparation method thereof |
| CN105832572A (en) * | 2016-04-07 | 2016-08-10 | 广州宏度精细化工有限公司 | Amino acid facial cleanser and preparation method thereof |
| CN105997768A (en) * | 2016-07-29 | 2016-10-12 | 济宁医学院 | Mild moistening amino acid facial cleanser |
Non-Patent Citations (3)
| Title |
|---|
| 徐良: ""洗面奶及其配方技术概述"", 《中国化妆品》 * |
| 李小迪: ""协同增效抗痘系列化妆品配方开发"", 《香料香精化妆品》 * |
| 谢惠英等: ""几种植物提取物在化妆品中的应用现状"", 《香料香精化妆品》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107485582A (en) * | 2017-08-18 | 2017-12-19 | 苏州莱奥生物技术有限公司 | A kind of frosted oil control facial cleanser |
| CN111494279A (en) * | 2020-05-07 | 2020-08-07 | 广东柏俐臣生物科技有限公司 | Cleaning cosmetic and preparation method thereof |
| CN113398051A (en) * | 2020-10-12 | 2021-09-17 | 中华全国供销合作总社南京野生植物综合利用研究所 | Plant combined extract for removing mites and acnes as well as preparation method and application thereof |
| CN113398051B (en) * | 2020-10-12 | 2022-08-23 | 中华全国供销合作总社南京野生植物综合利用研究所 | Plant combined extract for removing mites and acnes as well as preparation method and application thereof |
| CN112494381A (en) * | 2020-11-18 | 2021-03-16 | 美佳亚太投资有限公司 | Shaddock white capsule microparticle and preparation method and application thereof |
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