CN106726789A - A kind of sweet wormwood bacterium-suppressing shower lotion and preparation method thereof - Google Patents
A kind of sweet wormwood bacterium-suppressing shower lotion and preparation method thereof Download PDFInfo
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- CN106726789A CN106726789A CN201710151161.4A CN201710151161A CN106726789A CN 106726789 A CN106726789 A CN 106726789A CN 201710151161 A CN201710151161 A CN 201710151161A CN 106726789 A CN106726789 A CN 106726789A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D10/00—Compositions of detergents, not provided for by one single preceding group
- C11D10/04—Compositions of detergents, not provided for by one single preceding group based on mixtures of surface-active non-soap compounds and soap
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
- C11D1/14—Sulfonic acids or sulfuric acid esters; Salts thereof derived from aliphatic hydrocarbons or mono-alcohols
- C11D1/146—Sulfuric acid esters
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/02—Anionic compounds
- C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
- C11D1/29—Sulfates of polyoxyalkylene ethers
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- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/66—Non-ionic compounds
- C11D1/662—Carbohydrates or derivatives
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
- C11D1/88—Ampholytes; Electroneutral compounds
- C11D1/90—Betaines
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Abstract
The present invention relates to household chemicals technical field, in particular to a kind of sweet wormwood bacterium-suppressing shower lotion and preparation method thereof.Its raw material includes 2~3wt% of sweet wormwood wax soap lye, 1~3wt% of Artemisinin, the 0.5wt% of sweet wormwood volatile oil 0.1.Each effective constituents in sweet wormwood are taken full advantage of, effective sterilization, desinsection, degerming effect is reached, and preparation method is simple, easily operated.
Description
Technical field
The present invention relates to household chemicals technical field, in particular to a kind of sweet wormwood bacterium-suppressing shower lotion and its preparation
Method.
Background technology
As the progress and development of society, daily life level are improved constantly, the requirement to details articles for use is also got over
Come higher, during using shower cream, people are not only required to decontaminate de-sludging, it is also desirable to degerming bacteria resistance function.
Artemisinin, with significant Antimalarial, while also having antitumor, anti-lupus erythematosus, anti-schistosome, bow
Other parasites such as shape worm, Pneumocystis carinii, Paragonismus westermani, its derivative sodium artesunate is to golden grape, Fu Shi dysentery
Bacillus, Escherichia coli, micrococcus catarrhalis, A type and Bacillus paratyphosus B have certain antibacterial action, while qinghaosu is to suppression
Scar proliferation processed is inhibited.
Because qinghaosu has above-mentioned effect, apply it to and can significantly improve in washing, skincare product washing, skin care and use
The sterilization of product and health-care effect, but focus primarily upon sweet wormwood in washing and the skincare product containing Artemisinin is prepared at present
The method that element is extracted and added after refined, and the utilization of other compositions to containing in sweet wormwood is less, causes a large amount of active materials
It is wasted.
Part is utilized to the extract in other sweet wormwoods in addition to qinghaosu in the prior art, such as Chinese patent Shen
Application and sweet wormwood bacterium-suppressing shower lotion of a kind of Artemisinin in bath article please be disclosed in CN101461770A, wherein making
With sweet wormwood ethanol extract, decocting liquid or sweet wormwood volatile oil, but above-mentioned technical proposal is in actual applications, and sweet wormwood ethanol is extracted
Thing extracted amount is few, and active principle separates difficult, and active constituent content in sweet wormwood is relatively low, causes the big of sweet wormwood active ingredient
While amount is wasted, it is impossible to reach preferable antibacterial, bacteria-eliminating efficacy.
The content of the invention
Regarding to the issue above, the present invention proposes a kind of sweet wormwood bacterium-suppressing shower lotion and preparation method thereof, can be effectively antibacterial
It is sterilized.
To achieve these goals, the technical solution adopted in the present invention is a kind of sweet wormwood bacterium-suppressing shower lotion, its raw material bag
2~3wt% of sweet wormwood wax soap lye, 1~3wt% of Artemisinin, sweet wormwood volatile oil 0.1-0.5wt% are included, described sweet wormwood wax soap lye is
As obtained by saponification, described Artemisinin is qinghaosu mixed with artemisinin derivative to sweet wormwood herb wax in sweet wormwood herb
Close.
Further, the preparation process of described sweet wormwood wax soap lye is comprised the following steps：
1. remaining mother liquor after qinghaosu will be extracted（In qinghaosu extraction process, the more than qinghaosu for extracting is main to also have
The materials such as sweet wormwood herb wax, sweet wormwood volatile oil and chlorophyll, obtain sweet wormwood waste material mother liquor after separating qinghaosu）By steam
Rinse, obtain sweet wormwood wax；
2. sweet wormwood wax is added to the water, continues to be cooled down after stirring 5~10min after being heated with stirring to boiling, remove the low ester type waxes in top,
Obtain the ester type waxes high in water-bed portion；
3. ester type waxes high is added in aqueous slkali and is heated to 90~95 DEG C and carries out saponification 4-6h, add salt to separate out it afterwards, separated
Sweet wormwood wax soap lye solid；
4. sweet wormwood soap lye solid is put in water again and is heated, add citric acid to carry out adjusting pH value to 7~9, analyse it with salt again
Go out, obtain sweet wormwood wax soap lye solid；
5. liquid can be melted at sweet wormwood wax soap lye solid being heated into 40~55 DEG C, sweet wormwood wax soap lye is obtained.
Further, described aqueous slkali is sodium hydroxide solution, and concentration is 2wt%.
Further, the qinghaosu：Artemisinin derivative=3：1.
Preferably, a kind of sweet wormwood bacterium-suppressing shower lotion, its raw material includes the wt% of 50%APG 3~5, hydroxyethyl cellulose 0.1
It is~0.3 10~12 3~5 5~7 wt% of wt%, CAB-35 of wt%, K12A of wt%, AESA, the wt% of sweet wormwood wax soap lye 2~3, sweet
2~3 wt% of oil, the wt% of dipotassium glycyrrhizinate 0.04~0.06,0.05~0.15 wt% of wt%, EDTA-2Na of boric acid 0.1~0.3,
0.1~0.3wt% of Artemisinin, sweet wormwood volatile oil 0.1-0.5wt% and the balance of sweet wormwood water cooking liquids of 0~0.2wt% of additive.
Further, organic solvent is also included in described sweet wormwood bacterium-suppressing shower lotion raw material, described Artemisinin needs
Used after being dissolved with organic solvent.
Further, described sweet wormwood water cooking liquid is sweet wormwood cured leaf fresh by weight:Deionized water=1:4~6,85
25~30min, filtering gained are heated at~95 DEG C.
Further, described additive is one or more in pigment, preservative, thickener.
Sweet wormwood bacterium-suppressing shower lotion as described above, its preparation method is comprised the following steps：
A. prepared by sweet wormwood extract solution：Fresh sweet wormwood cured leaf is chosen by weight：Deionized water solid-to-liquid ratio=1:4~6 at 85~95 DEG C
25~30min of lower heating, filtering, obtains sweet wormwood water cooking liquid；
B. Artemisinin is dissolved with organic solvent, it is standby with the sweet wormwood liquid of 30~50wt% of Artemisinin content；
C. hydroxyethyl cellulose sweet wormwood water cooking liquid is dissolved at 905 DEG C, it is 2wt%'s to be configured to hydroxyethyl cellulose concentration
Solution, it is standby；
D. EDTA-2Na is added in sweet wormwood water cooking liquid and is completely dissolved, K12A stirrings are added at being warmed up to 80~85 DEG C, make its complete
CL, into after transparency liquid, adds APG, AESA, CAB-35, sweet wormwood wax soap lye, glycerine, dipotassium glycyrrhizinate, boric acid, stirring
And vacuumize, it is emulsified completely and homogeneous, obtain milky white shape thick liquid；
E. after homogeneous to be emulsified, temperature drops to 40~45 DEG C, under stirring add hydroxyethyl cellulose solution stirring 10~
15min, adds sweet wormwood liquid and additive, continues to stir 10~15min, cools to room temperature, obtains shower cream product.
Preferably, fresh sweet wormwood cured leaf in the step a：Deionized water solid-to-liquid ratio=1:5.
Described organic solvent is double de- ethanol and double desacetoxy ethyl esters.
Further, in the step d mixing speed be 60~70r/min, vacuum be -0.8~-0.1MPa, stirring 20~
30min。
Preferably, mixing speed is 65r/min in the step d, vacuum is -0.4 MPa, stirs 25min.
Further, mixing speed is 45~55 r/min in the step e.
Preferably, mixing speed is 50 r/min in the step e.
There is advantages below using scheme of the present invention：
1. add sweet wormwood wax soap lye to contain various antipathogenic compositions in sweet wormwood bacterium-suppressing shower lotion of the present invention, it is antibacterial very bright
It is aobvious；
2. deionized water is substituted for sweet wormwood water cooking liquid in being formulated, the content of sweet wormwood active ingredient in shower cream is improved；
3. coordinate sweet wormwood water cooking liquid added with qinghaosu or artemisinin derivative, sweet wormwood wax soap lye, be mutually combined together, make sweet wormwood
In combined with antipathogenic composition, make sweet wormwood it is antibacterial reach it is optimal and being capable of effective disinfection and deinsectization；
4. sweet wormwood wax soap lye is prepared into using sweet wormwood high ester wax, saponification is complete, it is to avoid low ester type waxes exists all the time in saponification process
Solution surface, it is difficult to saponification is completely, no complete sweet wormwood wax soap lye of saponification can glue hand, can't be washed off；
5. product takes full advantage of the various active ingredients in sweet wormwood, does not result in the waste of active ingredient；
6. product can effective clearing away summerheat, except steaming, preventing malaria；
7. preparation process of the present invention is simple, and preparation continuity, universality are good, significantly reduce production cost, significantly improve product
Product quality.
Specific embodiment
The present invention is described in further detail below by specific embodiment.
Embodiment 1：A kind of sweet wormwood bacterium-suppressing shower lotion, its raw material include 2~3wt% of sweet wormwood wax soap lye, Artemisinin 1~
3wt%, 0.1~0.5wt% of sweet wormwood volatile oil, described sweet wormwood wax soap lye are that the sweet wormwood herb wax in sweet wormwood herb passes through saponification institute
, described Artemisinin is qinghaosu and the mixing of artemisinin derivative.
The preparation process of described sweet wormwood wax soap lye is comprised the following steps：
1. remaining mother liquor obtains sweet wormwood wax by steam flush after qinghaosu being extracted；
2. sweet wormwood wax is added to the water, continues to be cooled down after stirring 5~10min after being heated with stirring to boiling, remove the low ester type waxes in top,
Obtain the ester type waxes high in water-bed portion；
3. ester type waxes high is added in aqueous slkali and is heated to 90~95 DEG C and carries out saponification 4-6h, add salt to separate out it afterwards, separated
Sweet wormwood wax soap lye solid；
4. sweet wormwood soap lye solid is put in water again and is heated, add citric acid to carry out adjusting pH value to 7~9, analyse it with salt again
Go out, obtain sweet wormwood wax soap lye solid；
5. liquid can be melted at sweet wormwood wax soap lye solid being heated into 40~55 DEG C, sweet wormwood wax soap lye is obtained.
Described aqueous slkali is sodium hydroxide solution, and concentration is 2wt%.
The qinghaosu：Artemisinin derivative=3：1.
Embodiment 2：A kind of sweet wormwood bacterium-suppressing shower lotion, its raw material include the wt% of 50%APG 4, hydroxyethyl cellulose 0.2wt%,
46 wt% of wt%, CAB-35 of wt%, K12A of AESA 11, the wt% of sweet wormwood wax soap lye 2.5, the wt% of glycerine 2.5, dipotassium glycyrrhizinate
0.05wt%, boric acid 0.2 wt%, EDTA-2Na 0.1wt%, Artemisinin 0.2wt%, sweet wormwood volatile oil 0.3wt% and additive
0.1wt%, balance of sweet wormwood water cooking liquid.Also include organic solvent in described sweet wormwood bacterium-suppressing shower lotion raw material, described sweet wormwood is carried
Taking thing needs to be used after being dissolved with organic solvent.Described sweet wormwood wax soap lye is that the sweet wormwood herb wax in sweet wormwood herb passes through saponification
Gained, described Artemisinin is qinghaosu and the mixing of artemisinin derivative.
Further, the preparation process of described sweet wormwood wax soap lye is comprised the following steps：
1. remaining mother liquor obtains sweet wormwood wax by steam flush after qinghaosu being extracted；
2. sweet wormwood wax is added to the water, continues to be cooled down after stirring 5~10min after being heated with stirring to boiling, remove the low ester type waxes in top,
Obtain the ester type waxes high in water-bed portion；
3. ester type waxes high is added in aqueous slkali and is heated to 90~95 DEG C and carries out saponification 4-6h, add salt to separate out it afterwards, separated
Sweet wormwood wax soap lye solid；
4. sweet wormwood soap lye solid is put in water again and is heated, add citric acid to carry out adjusting pH value to 7~9, analyse it with salt again
Go out, obtain sweet wormwood wax soap lye solid；
5. liquid can be melted at sweet wormwood wax soap lye solid being heated into 40~55 DEG C, sweet wormwood wax soap lye is obtained.
Described aqueous slkali is sodium hydroxide solution, and concentration is 2wt%.
The qinghaosu：Artemisinin derivative=3：1.
Described sweet wormwood water cooking liquid is sweet wormwood cured leaf fresh by weight:Deionized water=1:5, add at 85~95 DEG C
25~30min of heat, filtering gained.
Described additive is pigment, the mixing of preservative.
Described organic solvent is double de- ethanol and double desacetoxy ethyl esters.
Sweet wormwood bacterium-suppressing shower lotion as described above, its preparation method is comprised the following steps：
A. prepared by sweet wormwood extract solution：Fresh sweet wormwood cured leaf is chosen by weight：Deionized water solid-to-liquid ratio=1:5 at 85~95 DEG C
25~30min of heating, filtering obtains sweet wormwood water cooking liquid；
B. Artemisinin is dissolved with double de- ethanol and double desacetoxy ethyl esters, with the sweet wormwood of 30~50wt% of Artemisinin content
Liquid is standby；
C. hydroxyethyl cellulose sweet wormwood water cooking liquid is dissolved at 905 DEG C, it is 2wt%'s to be configured to hydroxyethyl cellulose concentration
Solution, it is standby；
D. EDTA-2Na is added in sweet wormwood water cooking liquid and is completely dissolved, K12A stirrings are added at being warmed up to 80~85 DEG C, make its complete
CL, into after transparency liquid, adds APG, AESA, CAB-35, sweet wormwood wax soap lye, glycerine, dipotassium glycyrrhizinate, boric acid, stirring
And vacuumize, it is emulsified completely and homogeneous, obtain milky white shape thick liquid, mixing speed is 65r/min, vacuum for-
0.4MPa, stirs 25min；
E. after homogeneous to be emulsified, temperature drops to 40~45 DEG C, under stirring add hydroxyethyl cellulose solution stirring 10~
15min, mixing speed is 50 r/min, adds sweet wormwood liquid and additive, continues to stir 10~15min, cools to room temperature, is obtained
To shower cream product.
Embodiment 3：A kind of sweet wormwood bacterium-suppressing shower lotion, its raw material include the wt% of 50%APG 3, hydroxyethyl cellulose 0.1wt%,
35 wt% of wt%, CAB-35 of wt%, K12A of AESA 10, the wt% of sweet wormwood wax soap lye 2, the wt% of glycerine 2, dipotassium glycyrrhizinate
0.04wt%, boric acid 0.1 wt%, EDTA-2Na 0.05wt%, Artemisinin 0.1wt%, sweet wormwood volatile oil 0.1wt% and addition
Agent 0.2wt%, balance of sweet wormwood water cooking liquid.Also include organic solvent, described sweet wormwood in described sweet wormwood bacterium-suppressing shower lotion raw material
Extract needs to be used after being dissolved with organic solvent.Described sweet wormwood wax soap lye is that the sweet wormwood herb wax in sweet wormwood herb passes through soap
Change gained, described Artemisinin is qinghaosu and the mixing of artemisinin derivative.
Further, the preparation process of described sweet wormwood wax soap lye is comprised the following steps：
1. remaining mother liquor obtains sweet wormwood wax by steam flush after qinghaosu being extracted；
2. sweet wormwood wax is added to the water, continues to be cooled down after stirring 5~10min after being heated with stirring to boiling, remove the low ester type waxes in top,
Obtain the ester type waxes high in water-bed portion；
3. ester type waxes high is added in aqueous slkali and is heated to 90~95 DEG C and carries out saponification 4-6h, add salt to separate out it afterwards, separated
Sweet wormwood wax soap lye solid；
4. sweet wormwood soap lye solid is put in water again and is heated, add citric acid to carry out adjusting pH value to 7~9, analyse it with salt again
Go out, obtain sweet wormwood wax soap lye solid；
5. liquid can be melted at sweet wormwood wax soap lye solid being heated into 40~55 DEG C, sweet wormwood wax soap lye is obtained.
Described aqueous slkali is sodium hydroxide solution, and concentration is 2wt%.
The qinghaosu：Artemisinin derivative=3：1.
Described sweet wormwood water cooking liquid is sweet wormwood cured leaf fresh by weight:Deionized water=1:4, add at 85~95 DEG C
25~30min of heat, filtering gained.
Described additive is pigment, preservative, the mixing of thickener.
Described organic solvent is double de- ethanol and double desacetoxy ethyl esters.
Sweet wormwood bacterium-suppressing shower lotion as described above, its preparation method is comprised the following steps：
A. prepared by sweet wormwood extract solution：Fresh sweet wormwood cured leaf is chosen by weight：Deionized water solid-to-liquid ratio=1:5 at 85~95 DEG C
25~30min of heating, filtering obtains sweet wormwood water cooking liquid；
B. Artemisinin is dissolved with double de- ethanol and double desacetoxy ethyl esters, with the sweet wormwood of 30~50wt% of Artemisinin content
Liquid is standby；
C. hydroxyethyl cellulose sweet wormwood water cooking liquid is dissolved at 905 DEG C, it is 2wt%'s to be configured to hydroxyethyl cellulose concentration
Solution, it is standby；
D. EDTA-2Na is added in sweet wormwood water cooking liquid and is completely dissolved, K12A stirrings are added at being warmed up to 80~85 DEG C, make its complete
CL, into after transparency liquid, adds APG, AESA, CAB-35, sweet wormwood wax soap lye, glycerine, dipotassium glycyrrhizinate, boric acid, stirring
And vacuumize, it is emulsified completely and homogeneous, obtain milky white shape thick liquid, mixing speed is 60r/min, vacuum for-
0.1MPa, stirs 20min；
E. after homogeneous to be emulsified, temperature drops to 40~45 DEG C, under stirring add hydroxyethyl cellulose solution stirring 10~
15min, mixing speed is 45 r/min, adds sweet wormwood liquid and additive, continues to stir 10~15min, cools to room temperature, is obtained
To shower cream product.
Embodiment 4：A kind of sweet wormwood bacterium-suppressing shower lotion, its raw material include the wt% of 50%APG 6, hydroxyethyl cellulose 0.3wt%,
57 wt% of wt%, CAB-35 of wt%, K12A of AESA 12, the wt% of sweet wormwood wax soap lye 3, the wt% of glycerine 3, dipotassium glycyrrhizinate
0.06wt%, boric acid 0.3 wt%, EDTA-2Na 0.15wt%, Artemisinin 0.3wt%, sweet wormwood volatile oil 0.5wt%, it is balance of
Sweet wormwood water cooking liquid.Also include organic solvent in described sweet wormwood bacterium-suppressing shower lotion raw material, described Artemisinin is needed with having
Used after the dissolving of machine solvent.Described sweet wormwood wax soap lye be sweet wormwood herb wax in sweet wormwood herb as obtained by saponification, it is described
Artemisinin is the mixing of qinghaosu and artemisinin derivative.
Further, the preparation process of described sweet wormwood wax soap lye is comprised the following steps：
1. remaining mother liquor obtains sweet wormwood wax by steam flush after qinghaosu being extracted；
2. sweet wormwood wax is added to the water, continues to be cooled down after stirring 5~10min after being heated with stirring to boiling, remove the low ester type waxes in top,
Obtain the ester type waxes high in water-bed portion；
3. ester type waxes high is added in aqueous slkali and is heated to 90~95 DEG C and carries out saponification 4-6h, add salt to separate out it afterwards, separated
Sweet wormwood wax soap lye solid；
4. sweet wormwood soap lye solid is put in water again and is heated, add citric acid to carry out adjusting pH value to 7~9, analyse it with salt again
Go out, obtain sweet wormwood wax soap lye solid；
5. liquid can be melted at sweet wormwood wax soap lye solid being heated into 40~55 DEG C, sweet wormwood wax soap lye is obtained.
Described aqueous slkali is sodium hydroxide solution, and concentration is 2wt%.
The qinghaosu：Artemisinin derivative=3：1.
Described sweet wormwood water cooking liquid is sweet wormwood cured leaf fresh by weight:Deionized water=1:6, add at 85~95 DEG C
25~30min of heat, filtering gained.
Described additive is pigment, the mixing of preservative.
Sweet wormwood bacterium-suppressing shower lotion as described above, its preparation method is comprised the following steps：
A. prepared by sweet wormwood extract solution：Fresh sweet wormwood cured leaf is chosen by weight：Deionized water solid-to-liquid ratio=1:5 at 85~95 DEG C
25~30min of heating, filtering obtains sweet wormwood water cooking liquid；
B. Artemisinin is dissolved with double de- ethanol and double desacetoxy ethyl esters, with the sweet wormwood of 30~50wt% of Artemisinin content
Liquid is standby；
C. hydroxyethyl cellulose sweet wormwood water cooking liquid is dissolved at 905 DEG C, it is 2wt%'s to be configured to hydroxyethyl cellulose concentration
Solution, it is standby；
D. EDTA-2Na is added in sweet wormwood water cooking liquid and is completely dissolved, K12A stirrings are added at being warmed up to 80~85 DEG C, make its complete
CL, into after transparency liquid, adds APG, AESA, CAB-35, sweet wormwood wax soap lye, glycerine, dipotassium glycyrrhizinate, boric acid, stirring
And vacuumize, it is emulsified completely and homogeneous, obtain milky white shape thick liquid, mixing speed is 70r/min, vacuum for-
0.8MPa, stirs 30min；
E. after homogeneous to be emulsified, temperature drops to 40~45 DEG C, under stirring add hydroxyethyl cellulose solution stirring 10~
15min, mixing speed is 55 r/min, adds sweet wormwood liquid, continues to stir 10~15min, cools to room temperature, obtains shower cream
Product.
Embodiment 5：A kind of sweet wormwood bacterium-suppressing shower lotion, its raw material include the wt% of 50%APG 4, hydroxyethyl cellulose 0.2wt%,
46 wt% of wt%, CAB-35 of wt%, K12A of AESA 11, the wt% of sweet wormwood wax soap lye 2.5, the wt% of glycerine 2.5, dipotassium glycyrrhizinate
0.05wt%, boric acid 0.2 wt%, EDTA-2Na 0.1wt%, Artemisinin 0.2wt%, sweet wormwood volatile oil 0.3wt% and additive
0.2wt%, balance of sweet wormwood water cooking liquid.Also include organic solvent in described sweet wormwood bacterium-suppressing shower lotion raw material, described sweet wormwood is carried
Taking thing needs to be used after being dissolved with organic solvent.Described sweet wormwood wax soap lye is that the sweet wormwood herb wax in sweet wormwood herb passes through saponification
Gained, described Artemisinin is qinghaosu and the mixing of artemisinin derivative.
Further, the preparation process of described sweet wormwood wax soap lye is comprised the following steps：
1. remaining mother liquor obtains sweet wormwood wax by steam flush after qinghaosu being extracted；
2. sweet wormwood wax is added to the water, continues to be cooled down after stirring 5~10min after being heated with stirring to boiling, remove the low ester type waxes in top,
Obtain the ester type waxes high in water-bed portion；
3. ester type waxes high is added in aqueous slkali and is heated to 90~95 DEG C and carries out saponification 4-6h, add salt to separate out it afterwards, separated
Sweet wormwood wax soap lye solid；
4. sweet wormwood soap lye solid is put in water again and is heated, add citric acid to carry out adjusting pH value to 7~9, analyse it with salt again
Go out, obtain sweet wormwood wax soap lye solid；
5. liquid can be melted at sweet wormwood wax soap lye solid being heated into 40~55 DEG C, sweet wormwood wax soap lye is obtained.
Described sweet wormwood water cooking liquid is sweet wormwood cured leaf fresh by weight:Deionized water=1:5, add at 85~95 DEG C
25~30min of heat, filtering gained.
Described additive is pigment, the mixing of preservative.
Sweet wormwood bacterium-suppressing shower lotion as described above, its preparation method is comprised the following steps：
A. prepared by sweet wormwood extract solution：Fresh sweet wormwood cured leaf is chosen by weight：Deionized water solid-to-liquid ratio=1:5 at 85~95 DEG C
25~30min of heating, filtering obtains sweet wormwood water cooking liquid；
B. Artemisinin is dissolved with double de- ethanol and double desacetoxy ethyl esters, with the sweet wormwood of 30~50wt% of Artemisinin content
Liquid is standby；
C. hydroxyethyl cellulose sweet wormwood water cooking liquid is dissolved at 905 DEG C, it is 2wt%'s to be configured to hydroxyethyl cellulose concentration
Solution, it is standby；
D. EDTA-2Na is added in sweet wormwood water cooking liquid and is completely dissolved, K12A stirrings are added at being warmed up to 80~85 DEG C, make its complete
CL, into after transparency liquid, adds APG, AESA, CAB-35, sweet wormwood wax soap lye, glycerine, dipotassium glycyrrhizinate, boric acid, stirring
And vacuumize, it is emulsified completely and homogeneous, obtain milky white shape thick liquid；
E. after homogeneous to be emulsified, temperature drops to 40~45 DEG C, under stirring add hydroxyethyl cellulose solution stirring 10~
15min, adds sweet wormwood liquid and additive, continues to stir 10~15min, cools to room temperature, obtains shower cream product.
The preferred embodiments of the present invention are the foregoing is only, is not intended to limit the invention, for the skill of this area
For art personnel, there can be various modifications and variations in the spirit and principles in the present invention, these equivalent modifications or replacement etc.,
It is all contained within protection scope of the present invention.
Claims (10)
1. a kind of sweet wormwood bacterium-suppressing shower lotion, it is characterised in that：Its raw material include 2~3wt% of sweet wormwood wax soap lye, Artemisinin 1~
3wt%, sweet wormwood volatile oil 0.1-0.5wt%, described sweet wormwood wax soap lye are that the sweet wormwood herb wax in sweet wormwood herb passes through saponification institute
, described Artemisinin is qinghaosu and the mixing of artemisinin derivative.
2. a kind of sweet wormwood bacterium-suppressing shower lotion according to claim 1, it is characterised in that the preparation of described sweet wormwood wax soap lye
Process is comprised the following steps：
1. remaining mother liquor obtains sweet wormwood wax by steam flush after qinghaosu being extracted；
2. sweet wormwood wax is added to the water, continues to be cooled down after stirring 5~10min after being heated with stirring to boiling, remove the low ester type waxes in top,
Obtain the ester type waxes high in water-bed portion；
3. ester type waxes high is added in aqueous slkali and is heated to 90~95 DEG C and carries out 4~6h of saponification, add salt to separate out it afterwards, separated
Sweet wormwood wax soap lye solid；
4. sweet wormwood soap lye solid is put in water again and is heated, add citric acid to carry out adjusting pH value to 7-9, analyse it with salt again
Go out, obtain sweet wormwood wax soap lye solid；
5. liquid can be melted at sweet wormwood wax soap lye solid being heated into 40~55 DEG C, sweet wormwood wax soap lye is obtained.
3. a kind of sweet wormwood bacterium-suppressing shower lotion according to claim 2, it is characterised in that：Described aqueous slkali is NaOH
Solution, concentration is 2wt%.
4. a kind of sweet wormwood bacterium-suppressing shower lotion according to claim 1, it is characterised in that：The qinghaosu：Qinghaosu derives
Thing=3：1.
5. according to a kind of any described sweet wormwood bacterium-suppressing shower lotions of claim 1-4, it is characterised in that：Its raw material includes 50%APG
3~5 wt%, 10~12 3~5 wt%, the CAB-35 5~7 of wt%, K12A of wt%, AESA of hydroxyethyl cellulose 0.1~0.3
Wt%, the wt% of sweet wormwood wax soap lye 2~3, the wt% of glycerine 2~3, the wt% of dipotassium glycyrrhizinate 0.04~0.06, boric acid 0.1~0.3
The wt% of wt%, EDTA-2Na 0.05~0.15,0.1~0.3wt% of Artemisinin, 0.1~0.5wt% of sweet wormwood volatile oil and addition
The wt% of agent 0~0.2, balance of sweet wormwood water cooking liquid.
6. a kind of sweet wormwood bacterium-suppressing shower lotion according to claim 5, it is characterised in that：Described sweet wormwood water cooking liquid is by weight
Amount part is than fresh sweet wormwood cured leaf:Deionized water=1:4~6,25~30min, filtering gained are heated at 85~95 DEG C.
7. a kind of sweet wormwood bacterium-suppressing shower lotion according to claim 5, it is characterised in that：Described additive is pigment, increases
Thick dose, one or more in preservative.
8. a kind of method of the sweet wormwood bacterium-suppressing shower lotion prepared as described in claim 1~7, it is characterised in that：Including following step
Suddenly：
A. prepared by sweet wormwood extract solution：Fresh sweet wormwood cured leaf is chosen by weight：Deionized water solid-to-liquid ratio=1:4~6 at 85~95 DEG C
25~30min of lower heating, filtering, obtains sweet wormwood water cooking liquid；
B. Artemisinin is dissolved with organic solvent, it is standby with the sweet wormwood liquid of 30~50wt% of Artemisinin content；
C. hydroxyethyl cellulose sweet wormwood extract solution is dissolved at 905 DEG C, is configured to the solution that concentration is 2wt%, it is standby；
D. EDTA-2Na is added in sweet wormwood water cooking liquid and is completely dissolved, K12A stirrings are added at being warmed up to 80~85 DEG C, make its complete
CL, into after transparency liquid, adds APG, AESA, CAB-35, sweet wormwood wax soap lye, glycerine, dipotassium glycyrrhizinate, boric acid, stirring
And vacuumize, it is emulsified completely and homogeneous, obtain milky white shape thick liquid；
E. after homogeneous to be emulsified, temperature drops to 40~45 DEG C, under stirring add hydroxyethyl cellulose solution stirring 10~
15min, adds sweet wormwood liquid and additive, continues to stir 10~15min, cools to room temperature, obtains shower cream product.
9. the preparation method of a kind of sweet wormwood bacterium-suppressing shower lotion according to claim 8, it is characterised in that：In the step b
Organic solvent is double de- ethanol and double desacetoxy ethyl esters.
10. the preparation method of a kind of sweet wormwood bacterium-suppressing shower lotion according to claim 8, it is characterised in that：In the step d
Mixing speed is 60~70r/min, and vacuum is -0.8~-0.1MPa, stirs 20~30min, and mixing speed is in the step e
45~55 r/min.
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| CN107280996A (en) * | 2017-08-24 | 2017-10-24 | 郭志军 | A kind of face mask of traditional Chinese medicine and preparation method thereof and application method |
| CN107955758A (en) * | 2017-12-23 | 2018-04-24 | 李春慧 | A kind of sweet wormwood soap and preparation method thereof |
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| CN113476347A (en) * | 2021-07-08 | 2021-10-08 | 河南天源海汇药物研究有限公司 | Sweet wormwood bath lotion formula and preparation method |
| CN113499297A (en) * | 2021-08-12 | 2021-10-15 | 广西和桂集团有限公司 | Artemisia apiacea anti-dandruff itching-relieving composition and preparation method and application thereof |
| WO2024012385A1 (en) * | 2022-07-15 | 2024-01-18 | 上海家化联合股份有限公司 | Composition comprising artemisiae annuae herba extract and functional active substance and use thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107280996A (en) * | 2017-08-24 | 2017-10-24 | 郭志军 | A kind of face mask of traditional Chinese medicine and preparation method thereof and application method |
| CN107955758A (en) * | 2017-12-23 | 2018-04-24 | 李春慧 | A kind of sweet wormwood soap and preparation method thereof |
| CN109276497A (en) * | 2018-11-12 | 2019-01-29 | 重庆菩璞生物科技有限公司 | A kind of application of the composition comprising Artemisinin in skin care item |
| CN113476347A (en) * | 2021-07-08 | 2021-10-08 | 河南天源海汇药物研究有限公司 | Sweet wormwood bath lotion formula and preparation method |
| CN113499297A (en) * | 2021-08-12 | 2021-10-15 | 广西和桂集团有限公司 | Artemisia apiacea anti-dandruff itching-relieving composition and preparation method and application thereof |
| WO2024012385A1 (en) * | 2022-07-15 | 2024-01-18 | 上海家化联合股份有限公司 | Composition comprising artemisiae annuae herba extract and functional active substance and use thereof |
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Application publication date: 20170531 |