CN106726663A - A kind of sweet wormwood bacteriostatic hand sanitizer - Google Patents

A kind of sweet wormwood bacteriostatic hand sanitizer Download PDF

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Publication number
CN106726663A
CN106726663A CN201710151155.9A CN201710151155A CN106726663A CN 106726663 A CN106726663 A CN 106726663A CN 201710151155 A CN201710151155 A CN 201710151155A CN 106726663 A CN106726663 A CN 106726663A
Authority
CN
China
Prior art keywords
sweet wormwood
artemisinin
hand sanitizer
bacteriostatic hand
fresh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710151155.9A
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Chinese (zh)
Inventor
张成林
舒代金
任永洁
刘剑
万兵
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sichuan Blue Bert Biological Polytron Technologies Inc
Original Assignee
Sichuan Blue Bert Biological Polytron Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sichuan Blue Bert Biological Polytron Technologies Inc filed Critical Sichuan Blue Bert Biological Polytron Technologies Inc
Priority to CN201710151155.9A priority Critical patent/CN106726663A/en
Publication of CN106726663A publication Critical patent/CN106726663A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/731Cellulose; Quaternized cellulose derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/596Mixtures of surface active compounds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The present invention relates to household chemicals technical field, in particular to a kind of sweet wormwood bacteriostatic hand sanitizer.Its raw materials by weight is calculated as hydroxyethyl cellulose 0.1~0.3%, AESA 5~7%, AES 3.5~4.5%, CAB 35 5~7%, 6,501 3.2~4.2%, EDTA 2Na 0.05~0.15%, Artemisinin 0.1~0.3%, sweet wormwood volatile oil 0.08~0.15%, additive 0.5~2%, Artemisinin solvent 0.1~0.7%, and balance of fresh sweet wormwood grass extracts the aqueous solution.Sweet wormwood class content of material is high in product, and sterilization, antibacterial, good antimicrobial effect, and fungistatic effect can keep for a long time.

Description

A kind of sweet wormwood bacteriostatic hand sanitizer
Technical field
The present invention relates to household chemicals technical field, in particular to a kind of sweet wormwood bacteriostatic hand sanitizer.
Background technology
As the progress and development of society, daily life level are improved constantly, the requirement to details articles for use is also got over Come higher, using during hand cleanser, people are not only required to decontaminate de-sludging, it is also desirable to long-term degerming antibacterial Function.
Artemisinin, with significant Antimalarial, while also having antitumor, anti-lupus erythematosus, anti-schistosome, bow Other parasites such as shape worm, Pneumocystis carinii, Paragonismus westermani, its derivative sodium artesunate is to golden grape, Fu Shi dysentery Bacillus, Escherichia coli, micrococcus catarrhalis, A type and Bacillus paratyphosus B have certain antibacterial action, while qinghaosu is to suppression Scar proliferation processed is inhibited.
Because qinghaosu has above-mentioned effect, apply it to and can significantly improve in washing, skincare product washing, skin care and use The sterilization of product and health-care effect, but focus primarily upon sweet wormwood in washing and the skincare product containing Artemisinin is prepared at present The method that element is extracted and added after refined, and the utilization to other compositions in sweet wormwood is less, causes a large amount of active materials unrestrained Expense is fallen.
The content of the invention
To solve the above problems, the present invention provides a kind of sweet wormwood bacteriostatic hand sanitizer, can be effectively sterilized, and can reach length Phase is antibacterial, protective effect.
To achieve these goals, the technical solution adopted in the present invention is that a kind of sweet wormwood bacteriostatic hand sanitizer, its raw material is pressed Percentage by weight be calculated as hydroxyethyl cellulose 0.1~0.3%, AESA 5~7%, AES 3.5~4.5%, CAB-35 5~7%, 6501 3.2~4.2%, EDTA-2Na 0.05~0.15%, Artemisinin 0.1~0.3%, sweet wormwood volatile oil 0.1~0.5%, Additive 0.5~2%, Artemisinin solvent 0.1~0.7%, balance of fresh sweet wormwood grass extract the aqueous solution.
Further, described Artemisinin is the mixing of qinghaosu and artemisinin derivative.
Preferably, qinghaosu in described Artemisinin:Artemisinin derivative=3:1.
Further, described additive is the multiple combination in pH adjusting agent, thickener, preservative, pigment, essence.
Further, described Artemisinin need to add the sweet wormwood liquid that 30~50wt% is configured in Artemisinin solvent Reuse.
Further, described Artemisinin solvent is double de- ethanol and double desacetoxy ethyl esters.
Further, it is that fresh sweet wormwood is carried out with 85~90 DEG C of deionized water that described fresh sweet wormwood grass extracts the aqueous solution 10~20min of immersion, filtering is obtained, fresh sweet wormwood described by weight:Deionized water=1:18~22.This solution has Stronger antibacterial and antiinflammation, can arrange in pairs or groups with qinghaosu or Artesunate, further enhance its antibacterial, bacteriostasis efficacy, together Shi Zengjia antibacterials, scope of restraining fungi.
Preferably, fresh sweet wormwood:Deionized water=1:20.
Further, in preparation process, described carboxyethyl cellulose need to first add fresh sweet wormwood grass to match somebody with somebody in extracting the aqueous solution 2wt% solution is made, it is standby.
Sweet wormwood bacteriostatic hand sanitizer of the present invention, using qinghaosu, artemisinin derivative, sweet wormwood volatile oil, fresh green grass or young crops Wormwood is extracted the aqueous solution and coordinates, and can play effective sterilized, bacteriostasis, and the term of validity is long, in taking full advantage of sweet wormwood Various active ingredients, substituted for conventional deionized water and effectively improve sweet wormwood material using the fresh sweet wormwood grass extraction aqueous solution Content, and fresh sweet wormwood grass extracts the aqueous solution with qinghaosu or artemisinin derivative also with synergy, can effectively be lifted Product bacteriostasis property, qinghaosu is processed again with artemisinin derivative after solvent dissolves, and qinghaosu is derived with sweet wormwood Thing distribution is more uniform.
Specific embodiment
The present invention is described in further detail below by specific embodiment.
Embodiment 1:A kind of sweet wormwood bacteriostatic hand sanitizer, its raw materials by weight be calculated as hydroxyethyl cellulose 0.2%, AESA 6%, AES 4%, CAB-35 6%, 6,501 3.7%, EDTA-2Na 0.1%, Artemisinin 0.2%, sweet wormwood volatile oil 0.3%th, additive 1%, Artemisinin solvent 0.4%, balance of fresh sweet wormwood grass extract the aqueous solution;Described Artemisinin It is the mixing of qinghaosu and artemisinin derivative, qinghaosu in described Artemisinin:Artemisinin derivative=3:1;It is described Additive be pH adjusting agent, thickener, the combination of preservative.
It is to carry out immersion 10 to fresh sweet wormwood with 85~90 DEG C of deionized water that described fresh sweet wormwood grass extracts the aqueous solution ~20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:20.
During preparation, solution, described Artemisinin are prepared into during Artemisinin first is added into Artemisinin solvent Solvent is double de- ethanol and double desacetoxy ethyl esters, and carboxyethyl cellulose adds fresh sweet wormwood grass to be configured in extracting the aqueous solution 2wt% solution, it is standby.
Embodiment 2:A kind of sweet wormwood bacteriostatic hand sanitizer, its raw materials by weight be calculated as hydroxyethyl cellulose 0.1%, AESA 5%, AES 4.5%, CAB-35 5%, 6,501 4.2%, EDTA-2Na 0.05%, Artemisinin 0.3%, sweet wormwood volatile oil 0.1%th, additive 0.5%, Artemisinin solvent 0.7%, balance of fresh sweet wormwood grass extract the aqueous solution;Described sweet wormwood is extracted Thing is the mixing of qinghaosu and artemisinin derivative, qinghaosu in described Artemisinin:Artemisinin derivative=3:1;Institute The additive stated is pH adjusting agent, thickener, pigment, the combination of essence.
It is to carry out immersion 10 to fresh sweet wormwood with 85~90 DEG C of deionized water that described fresh sweet wormwood grass extracts the aqueous solution ~20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:18.
During preparation, solution, described Artemisinin are prepared into during Artemisinin first is added into Artemisinin solvent Solvent is double de- ethanol and double desacetoxy ethyl esters, and carboxyethyl cellulose adds fresh sweet wormwood grass to be configured in extracting the aqueous solution 2wt% solution, it is standby.
Embodiment 3:A kind of sweet wormwood bacteriostatic hand sanitizer, its raw materials by weight be calculated as hydroxyethyl cellulose 0.3%, AESA 7%, AES 3.5%, CAB-35 7%, 6,501 3.2%, EDTA-2Na 0.15%, Artemisinin 0.1%, sweet wormwood volatile oil 0.5%th, the % of additive 2, Artemisinin solvent 0.1%, balance of fresh sweet wormwood grass extract the aqueous solution;Described Artemisinin It is the mixing of qinghaosu and artemisinin derivative.
It is to carry out immersion 10 to fresh sweet wormwood with 85~90 DEG C of deionized water that described fresh sweet wormwood grass extracts the aqueous solution ~20min, filtering, obtains, fresh sweet wormwood described by weight:Deionized water=1:22.
During preparation, solution, described Artemisinin are prepared into during Artemisinin first is added into Artemisinin solvent Solvent is double de- ethanol and double desacetoxy ethyl esters, standby.
The preferred embodiments of the present invention are the foregoing is only, is not intended to limit the invention, for the skill of this area For art personnel, there can be various modifications and variations in the spirit and principles in the present invention, these equivalent modifications or replacement etc., It is all contained within protection scope of the present invention.

Claims (8)

1. a kind of sweet wormwood bacteriostatic hand sanitizer, it is characterised in that its raw materials by weight is calculated as:Hydroxyethyl cellulose 0.1~ 0.3%th, AESA 5~7%, AES 3.5~4.5%, CAB-35 5~7%, 6,501 3.2~4.2%, EDTA-2Na 0.05~ 0.15%th, Artemisinin 0.1~0.3%, sweet wormwood volatile oil 0.08~0.15%, additive 0.5~2%, Artemisinin solvent 0.1~0.7%, balance of sweet wormwood water cooking liquid, described Artemisinin is the mixing of qinghaosu and artemisinin derivative.
2. a kind of sweet wormwood bacteriostatic hand sanitizer according to claim 1, it is characterised in that:Sweet wormwood in described Artemisinin Element:Artemisinin derivative=3:1.
3. a kind of sweet wormwood bacteriostatic hand sanitizer according to claim 1, it is characterised in that:Described additive is adjusted for pH Multiple combination in agent, thickener, preservative, pigment, essence.
4. a kind of sweet wormwood bacteriostatic hand sanitizer according to claim 1, it is characterised in that:Described Artemisinin adds blue or green The sweet wormwood liquid of 30~50wt% is configured in parthenium extract solvent, it is standby.
5. a kind of sweet wormwood bacteriostatic hand sanitizer according to claim 1 or 4, it is characterised in that:Described Artemisinin is molten Agent is double de- ethanol and double desacetoxy ethyl esters.
6. a kind of sweet wormwood bacteriostatic hand sanitizer according to claim 1, it is characterised in that:Described fresh sweet wormwood grass extracts water Solution is that 10~20min of immersion is carried out to fresh sweet wormwood with 85-90 DEG C of deionized water, filtering, is obtained, described by weight Fresh sweet wormwood:Deionized water=1:18~22.
7. a kind of sweet wormwood bacteriostatic hand sanitizer according to claim 6, it is characterised in that:Fresh sweet wormwood:Deionized water=1: 20。
8. a kind of sweet wormwood bacteriostatic hand sanitizer according to claim 1, it is characterised in that:Described carboxyethyl cellulose is added Fresh sweet wormwood grass is configured to 2wt% solution in extracting the aqueous solution, standby.
CN201710151155.9A 2017-03-14 2017-03-14 A kind of sweet wormwood bacteriostatic hand sanitizer Pending CN106726663A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710151155.9A CN106726663A (en) 2017-03-14 2017-03-14 A kind of sweet wormwood bacteriostatic hand sanitizer

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Application Number Priority Date Filing Date Title
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CN106726663A true CN106726663A (en) 2017-05-31

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461770A (en) * 2009-01-06 2009-06-24 华南农业大学 Use of southernwood extract in bath article and southernwood bacterium-suppressing shower lotion
CN103110543A (en) * 2012-11-15 2013-05-22 沈阳洪达信息科技有限公司 Sterilization hand sanitizer
CN105886166A (en) * 2016-04-22 2016-08-24 四川蓝伯特生物科技有限责任公司 Artemisia annua wax handmade soap and production method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101461770A (en) * 2009-01-06 2009-06-24 华南农业大学 Use of southernwood extract in bath article and southernwood bacterium-suppressing shower lotion
CN103110543A (en) * 2012-11-15 2013-05-22 沈阳洪达信息科技有限公司 Sterilization hand sanitizer
CN105886166A (en) * 2016-04-22 2016-08-24 四川蓝伯特生物科技有限责任公司 Artemisia annua wax handmade soap and production method thereof

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Application publication date: 20170531

RJ01 Rejection of invention patent application after publication