CN106716132A - 癌症的诊断 - Google Patents

癌症的诊断 Download PDF

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Publication number
CN106716132A
CN106716132A CN201580052886.7A CN201580052886A CN106716132A CN 106716132 A CN106716132 A CN 106716132A CN 201580052886 A CN201580052886 A CN 201580052886A CN 106716132 A CN106716132 A CN 106716132A
Authority
CN
China
Prior art keywords
cancer
sample
oncoprotein
patient
urine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580052886.7A
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English (en)
Chinese (zh)
Inventor
曾琦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agency for Science Technology and Research Singapore
Original Assignee
Agency for Science Technology and Research Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agency for Science Technology and Research Singapore filed Critical Agency for Science Technology and Research Singapore
Publication of CN106716132A publication Critical patent/CN106716132A/zh
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57575—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03048—Protein-tyrosine-phosphatase (3.1.3.48)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82—Translation products from oncogenes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Oncology (AREA)
CN201580052886.7A 2014-08-13 2015-08-13 癌症的诊断 Pending CN106716132A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SG10201404895XA SG10201404895XA (en) 2014-08-13 2014-08-13 Diagnosis
SG10201404895X 2014-08-13
PCT/SG2015/050259 WO2016024918A1 (en) 2014-08-13 2015-08-13 Diagnosis of cancer

Publications (1)

Publication Number Publication Date
CN106716132A true CN106716132A (zh) 2017-05-24

Family

ID=55304429

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580052886.7A Pending CN106716132A (zh) 2014-08-13 2015-08-13 癌症的诊断

Country Status (6)

Country Link
US (1) US20170234880A1 (https=)
EP (1) EP3189333A4 (https=)
JP (1) JP2017526916A (https=)
CN (1) CN106716132A (https=)
SG (2) SG10201404895XA (https=)
WO (1) WO2016024918A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110531082A (zh) * 2018-05-25 2019-12-03 国家纳米科学中心 用于乳腺癌检测及分子分型的外泌体检测装置和应用
CN110613735A (zh) * 2017-12-11 2019-12-27 浙江大学 NK细胞外泌体hsa-miR-9609在抗菌中的应用
CN118376789A (zh) * 2024-06-25 2024-07-23 南昌大学第一附属医院 一种用于诊断肺癌的检测试剂盒及应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018075825A1 (en) * 2016-10-19 2018-04-26 Northwestern University Extracellular vesicle-based diagnostics and engineered exosomes for targeted therapeutics against cancer
CN107058556A (zh) * 2017-05-09 2017-08-18 大连海事大学 一种用于评估硫丹促癌风险的方法
US20230266323A1 (en) * 2020-08-06 2023-08-24 Lsi Medience Corporation Diagnosis method for bladder cancer
CN112698033A (zh) * 2020-12-09 2021-04-23 复旦大学附属中山医院 一种血源性外泌体her2的检测方法及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010056337A2 (en) * 2008-11-12 2010-05-20 Caris Mpi, Inc. Methods and systems of using exosomes for determining phenotypes
WO2010070276A1 (en) * 2008-12-15 2010-06-24 Oxford Biomedica (Uk) Limited Method
CN101820910A (zh) * 2007-05-03 2010-09-01 新加坡科技研究局 结合细胞内prl-1多肽或prl-3多肽的抗体
WO2013036201A1 (en) * 2011-09-06 2013-03-14 Agency For Science, Technology And Research Polypeptide vaccine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1848742A1 (en) * 2005-01-28 2007-10-31 Attogen, Inc. Anti-prl-3 antibodies and methods of use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101820910A (zh) * 2007-05-03 2010-09-01 新加坡科技研究局 结合细胞内prl-1多肽或prl-3多肽的抗体
WO2010056337A2 (en) * 2008-11-12 2010-05-20 Caris Mpi, Inc. Methods and systems of using exosomes for determining phenotypes
WO2010070276A1 (en) * 2008-12-15 2010-06-24 Oxford Biomedica (Uk) Limited Method
WO2013036201A1 (en) * 2011-09-06 2013-03-14 Agency For Science, Technology And Research Polypeptide vaccine

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110613735A (zh) * 2017-12-11 2019-12-27 浙江大学 NK细胞外泌体hsa-miR-9609在抗菌中的应用
CN110623981A (zh) * 2017-12-11 2019-12-31 浙江大学 NK细胞外泌体hsa-miR-330-5p在抗菌中的应用
CN110664843A (zh) * 2017-12-11 2020-01-10 浙江大学 NK细胞外泌体hsa-miR-9550在抗菌中的应用
CN110613735B (zh) * 2017-12-11 2022-07-01 浙江大学 NK细胞外泌体hsa-miR-9609在抗菌中的应用
CN110664843B (zh) * 2017-12-11 2022-07-01 浙江大学 NK细胞外泌体hsa-miR-9550在抗菌中的应用
CN110531082A (zh) * 2018-05-25 2019-12-03 国家纳米科学中心 用于乳腺癌检测及分子分型的外泌体检测装置和应用
CN118376789A (zh) * 2024-06-25 2024-07-23 南昌大学第一附属医院 一种用于诊断肺癌的检测试剂盒及应用
CN118376789B (zh) * 2024-06-25 2024-09-13 南昌大学第一附属医院 一种用于诊断肺癌的检测试剂盒及应用

Also Published As

Publication number Publication date
US20170234880A1 (en) 2017-08-17
SG11201701076TA (en) 2017-03-30
WO2016024918A1 (en) 2016-02-18
SG10201404895XA (en) 2016-03-30
JP2017526916A (ja) 2017-09-14
EP3189333A1 (en) 2017-07-12
EP3189333A4 (en) 2018-04-18

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