CN106692834A - Medicinal liquor for treating kidney deficiency type osteoporosis - Google Patents

Abstract

The invention relates to medicinal liquor for treating kidney deficiency type osteoporosis. The medicinal liquor is prepared by soaking the following traditional Chinese medicinal materials with wine: herba taxilli, viscum liquiddambaricolum hayata, viscum angulatum heyne, Chinese angelica, radix achyranthis bidentatae, rhizoma drynariae, isodon ternifolius, rhizoma kaempferiae and Indochina dragonplum fruit. The medicinal liquor for treating the kidney deficiency type osteoporosis, disclosed by the invention, can treat both manifestation and root cause of disease in all rounds, and has the efficacy of reinforcing liver and kidney, strengthening muscles and bones, dredging tendons and muscles and expelling wind-damp.

Description

A kind of medicinal liquor for treating renal deficiency type osteoporosis

Technical field

The present invention relates to Chinese medicinal liquor field, and in particular to a kind of medicinal liquor for treating renal deficiency type osteoporosis and preparation method thereof.

Background technology

Osteoporosis is one group of osteopathy that many reasons cause, and bone tissue has normal calcification, and calcium salt is in normal rates with matrix, Metabolic bone disease with the characteristics of the reduction of unit volume inner bone tissues amount becomes.In most osteoporosises, the reduction of bone tissue is main Caused by bone absorption increases.With skeleton pain, it is easy to fracture and is characterized.Osteoporosis be one it is worldwide, more To get over the health problem for attracting people's attention, its incidence of disease is raised with the growth at age, and has obvious gender differences, typically Women is more than male.

Osteoporosis has no longer been the patent of the elderly, is shown according to omnibus survey, increasing young man's bone health Flash the redlight.The traditional Chinese medical science belongs to osteoporosis " atrophic debility of bones, bone are withered, heumatism " category, it is believed that its pathogenesis be kidney deficiency and It is insufficiency of the spleen, therefore for the interpretation of the cause, onset and process of an illness using nourishing disney and strengthening bone, the therapeutic rules for replenishing qi to invigorate the spleen.

First, nourishing disney and strengthening bone method

According to the tcm theory of " Shen controls bone ", kidney deficiency is that the morbidity of osteoporosis is crucial, bone it is powerful with it is fragile be essence in kidney The important symbol of prosperity and decline.Modern medicine thinks, the essence of kidney deficiency is that hypothalamus, hypophysis, gonad axis there occurs disorder, is caused into , there is osteoporosis in bone function reduction.Therefore suitable nourishing disney and strengthening bone is treated, if kidney essense is sufficient, muscles and bones is hard strong.

2nd, replenish qi to invigorate the spleen, liver is adjusted in promoting blood circulation

Insufficiency of the spleen then deficiency of kidney-essence, bone loses supports, and bone fragility is powerless, so that there is osteoporosis.Therefore the suitable inrigorating qi and promoting blood circulation for the treatment of, Liver is adjusted in invigorating the spleen.

Alcoholic strength temperature and taste is pungent, Wen Zheneng dispelling colds, pungent person can dissipate, thus wine can dredge the channels, promoting the circulation of qi and blood, exempt from numbness dissipating bind, Warm sun dispelling cold, energy soothing liver-qi stagnation, a surname's feelings are freely anticipated.The elite brewageed for cereal because of wine again, therefore can also help stomach.《Natural science will》 Carry：Equal three people of Wang Su, Zhang Heng, horse emits mist morning row.One people drinks, a human diet, and a people is on an empty stomach.Empty stomach person is dead, and satisfy trencherman Disease, alcohol user is good for.This shows that " wine gesture wards off evil, is better than the effect that work is eaten." combination of wine and medicine is to drink the one of health to enter greatly Step.Almost there is medicinal liquor to control the record of disease body-building bar none in the successive dynasties medicine works of China.Though the initial drinking behavior of the mankind Health of drinking can't be so referred to as, but have close contact with health care.Initial wine is the wild water of mankind's collection Fruit obtains suitable condition spontaneous fermentation when residue, because many wild fruits inherently have medical value, institute Natural " health liquor " can be deserved to be called with initial wine, it has certain protection and facilitation to health.Today with The progress of science and technology, is had developed to from the basis of the traditional handicraft of Traditional Chinese medicinal wine using extraction, extraction and bioengineering etc. Modernization meanses, extract the functional medicinal-liquor that the effective ingredient in Chinese medicine is made high content.

The content of the invention

It is an object of the invention to provide a kind of medicinal liquor for treating renal deficiency type osteoporosis.

The purpose of the present invention is realized by following technical scheme：

The medicinal liquor for the treatment of renal deficiency type osteoporosis of the present invention, is prepared from by the raw material including following weight portion：

Ramulus Taxilli 15-40 parts, 10-30 parts of maple parasitism, 15-40 parts of persimmon parasitism, Radix Angelicae Sinensis 5-15 parts, root of bidentate achyranthes 5-10 parts, bone Broken 3-10 parts of benefit, glaucocalyx rabdosia herb 3-10 parts, kaempferia galamga 5-15 parts, dracontomelon duperreanum 10-20 parts, 60-80% wine bases 400-600 Part.

Preferably, it is to be prepared from by the raw material of following weight portion：

Ramulus Taxilli 20-30 parts, 15-20 parts of maple parasitism, 20-30 parts of persimmon parasitism, Radix Angelicae Sinensis 8-12 parts, root of bidentate achyranthes 6-8 parts, bone it is broken Mend 5-8 parts, glaucocalyx rabdosia herb 5-8 parts, kaempferia galamga 8-12 parts, dracontomelon duperreanum 12-18 parts, 70% wine base 500-550 parts.

The following is the crude drug source of the medicinal liquor of present invention treatment renal deficiency type osteoporosis：

Ramulus Taxilli, is that Loranthaceae plant Ramulus Taxilli Taxillus chinensis (DC.) Danser dries stem and branch with leaf. 【Nature and flavor】Bitter, sweet, flat.【Return through】Return liver and kidney channel.【Indication】Filling liver kidney, strengthening the bones and muscles, wind-damp dispelling is antiabortive Unit.For arthralgia pain due to rheumatism, soreness and weakness of waist and knees, muscles and bones is powerless, and uterine bleeding passes through many, blood leaking in gestation, fetal irritability；Hypertension.

Maple is parasitic, and Loranthaceae mistletoe Viscμm articulatum Burm f Viscum articulatum Burm.f. are entered with complete stool Medicine.【Nature and flavor】Slight bitter, puts down.【Indication】Expelling wind and removing dampness, stimulates the circulation of the blood and cause the muscles and joints to relax, hemostasis.For rheumatic arthritis, waist Muscular strain, uterine bleeding, nosebleed epistaxis, leukorrhea, urinary tract infections.

Persimmon is parasitic, is the stem and branch with leaf of Loranthaceae plant ebonyshoot mistletoe branchlet and leaf.【Nature and flavor】It is bitter；It is mild-natured.【Return through】Liver；Lung； Stomach【Indication】Wind-damp dispelling；Strengthening the bones and muscles；Cough-relieving；Detumescence；Step-down.Main arthralgia pain due to rheumatism；Waist and leg ache；Cough；Cough up Blood；Stomachache；Fetal irritability；Boil；Hypertension.

Radix Angelicae Sinensis, is the dry root of umbelliferae angelica Angelica sinensis (Oliv.) Diels.【Nature and flavor】Sweet, It is pungent, temperature.【Return through】Return liver, the heart, the spleen channel.【Indication】Replenishing and activating blood, menstruction regulating and pain relieving relaxes bowel.For blood Empty sallow, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, dry constipation of intestines, arthralgia pain due to rheumatism, injury from falling down, carbuncle Subcutaneous ulcer sore.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine invigorate blood circulation.For closed dysmenorrhea, arthralgia pain due to rheumatism, injury from falling down.

The root of bidentate achyranthes, is the dry root of amaranthaceous plant root of bidentate achyranthes Achyranthes bidentata Blume..【Nature and flavor】Bitter, acid, It is flat.【Return through】Return liver and kidney channel.【Indication】Filling liver kidney, strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow is ensuringd proper downward flow of the blood.For waist and knee Ache, muscles and bones is powerless, Amenorrhea abdominal mass, dizziness due to hyperactivity of liver-YANG.

The rhizome of davallia, is the dry rhizome of Plants of Polypodiaceae Mongolian oak fern Drynaria fortunei (Kunze) J.Sm..【Property Taste】Hardship, temperature.【Return through】Return kidney, Liver Channel.【Indication】The strong bone of kidney tonifying, continues and hinders pain relieving.For lumbago due to the kidney deficiency, ear Ring is deaf, tooth mobility, falling winks frustrates, injured bone；Control outward alopecia areata, leucoderma.

Glaucocalyx rabdosia herb, glaucocalyx rabdosia herb is Labiatae Rabdosia plant meadow fescue Rabdcsia ternifolia (D.Don) Hara's dries herb, also known as Folium solani verbascifolii, typhoid fever are first-class, and bitter, micro-pungent are cool in nature, with clearing heat and detoxicating, removing jaundice dampness removing, The effect of detumescence, it is used for, for treating dysentery enteritis, icterepatitis, sphagitis, tonsillitis, urinary tract infection, bladder Inflammation, acute nephritis, swelling pain, influenza, venomous snake bite, toothache etc..

Kaempferia galamga, is the dry rhizome of zingiberaceous plant Kaempferia galanga Kaempferia galanga L..【Nature and flavor】It is pungent, temperature.【Return through】 Return stomach.【Indication】Promoting the circulation of qi middle benefit gas, help digestion, analgesic.For septum pectorale turgor, coldness and pain in the epigastrium, diet does not disappear.

Dracontomelon duperreanum, Anacardiaceae dracontomelon duperreanum Dracontomelon dao (Blanco) Merr.et Rolfe are used as medicine with fruit.【Property Taste】It is sweet；Acid；It is cool in nature【Return through】Spleen；Stomach；Liver Channel.【Indication】Stomach invigorating；Promote the production of body fluid；Sober up；Removing toxic substances.Staple food It is intended to depressed；Pyreticosis is thirsty；It is drunk；Abscess of throat；Pathogenic wind-toxic sore is itched.

Wine, warm in nature and taste is pungent, Wen Zheneng dispelling colds, pungent person can dissipate, thus wine can dredge the channels, promoting the circulation of qi and blood, exempt from numbness dissipating bind, Warm sun dispelling cold, energy soothing liver-qi stagnation, a surname's feelings are freely anticipated.The elite brewageed for cereal because of wine again, therefore can also help stomach.

Another aspect of the present invention there is provided the preparation method of the medicinal liquor of present invention treatment renal deficiency type osteoporosis：

(1) all 9 taste medicinal materials are taken, is cleaned, sterilizes, dries, is shredded；

(2) medicinal material after shredding adds wine base to soak 50-70 days；

(3) immersion gained medicated liquor is filtered, obtains filtrate；

(4) filtrate to add water and be deployed into 800-1500 parts with rice wine, and wine degree is 30-50%；

(5) filtered after deployed medicated liquor is clarified naturally；

(6) wine liquid after filtering is stored 5-10 days, obtains final product the medicinal liquor.

The preparation method of the medicinal liquor of present invention treatment renal deficiency type osteoporosis is preferably as follows：

(1) all 9 taste medicinal materials are taken, is cleaned, sterilizes, dries, is shredded；

(2) medicinal material after shredding adds rock sugar and wine base to soak 60 days；

(3) immersion gained medicated liquor is filtered, obtains filtrate；

(4) filtrate to add water and be deployed into 1000 parts with rice wine, and wine degree is 40-45%；

(5) filtered after deployed medicated liquor is clarified naturally；

(6) wine liquid after filtering is stored 7 days, obtains final product the medicinal liquor.

" kidney storing essence, main bone gives birth to marrow ", kidney deficiency is the basic reason that osteoporosis occurs, and kidney essense is sufficient, then the biochemistry of marrow has Source, bone can just obtain the abundant nourishing of marrow and firm strong, if kidney-jing deficiency is few, the change source of marrow is not enough, it is impossible to moisten nourishing the bone Bone, it is weak bone fragility occur, triggers osteoporosis.

Through present inventor's clinical and Germicidal efficacy for many years, it is believed that osteoporosis main pathogenesis are kidney deficiency, insufficiency of the spleen and blood stasis. The present invention be inventor product many years of experience used by Traditional Chinese medicinal liquor side, side in Ramulus Taxilli, the root of bidentate achyranthes, rhizome of davallia tonifying liver and kidney and strengthening bones and muscles, Chinese angelica blood supplementing is invigorated blood circulation, and is altogether monarch drug in a prescription；Maple is parasitic, persimmon parasitism wind-dispelling strengthening the bones and muscles is ministerial drug；Glaucocalyx rabdosia herb is clearing heat and detoxicating, mountain How promoting the circulation of qi middle benefit gas, dracontomelon duperreanum stomach invigorating promotes the production of body fluid altogether for adjuvant, treats both principal and secondary aspect of disease, and looks after comprehensive, filling liver kidney, strengthening the bones and muscles is played altogether, is relaxed The effect of grain, wind-damp dispelling.

A kind of medicinal liquor for treating renal deficiency type osteoporosis that the present invention is provided has advantages below：

1st, the medicinal liquor of the treatment renal deficiency type osteoporosis that the present invention is provided can treat both principal and secondary aspect of disease, and look after comprehensive, with filling liver kidney, by force Muscles and bones, relaxing muscles and tendons network, the effect of wind-damp dispelling.

2nd, clinical observation shows that the medicinal liquor of invention treatment renal deficiency type osteoporosis is to the total effective of renal deficiency type patients with osteoporosis Rate is 93.65%, can improve sufferers of osteoporosis face bone mineral content, improves its quality of life, shows good osteoporosis of preventing and treating Effect.

Specific embodiment

The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustrating the present invention Rather than limitation of the present invention.Essence of the invention belongs to claimed to the simple modifications that the present invention is carried out Scope.

Embodiment 1

Ramulus Taxilli 15g, maple parasitism 10g, persimmon parasitism 15g, Radix Angelicae Sinensis 5g, root of bidentate achyranthes 5g, rhizome of davallia 3g, glaucocalyx rabdosia herb 3g, Kaempferia galamga 5g, dracontomelon duperreanum 10g.All 9 taste medicinal materials are taken, cleaned, sterilize, dry, shredded, be 60% wine base 400g with alcoholic strength Immersion 50 days, immersion gained medicated liquor filtering takes that filtrate adds water and rice wine is deployed into 800g, and rectification degree is 30%, deployed Medicated liquor squeeze into semi-finished product cylinder, filtered after clarifying naturally, wine liquid after filtering is stored 5 days, the medicinal liquor is obtained final product, after inspection It is filling.

Embodiment 2

Ramulus Taxilli 40g, maple parasitism 30g, persimmon parasitism 40g, Radix Angelicae Sinensis 15g, root of bidentate achyranthes 10g, rhizome of davallia 10g, glaucocalyx rabdosia herb 10g, kaempferia galamga 15g, dracontomelon duperreanum 20g.All 9 taste medicinal materials are taken, cleaned, sterilize, dry, shredded, be 80% with alcoholic strength Wine base 600g soaks 70 days, immersion gained medicated liquor filtering, takes that filtrate adds water and rice wine is deployed into 1500g, and rectification degree is 60%, Deployed medicated liquor squeezes into semi-finished product cylinder, is filtered after clarifying naturally, and the wine liquid after filtering is stored 10 days, obtains final product the medicinal liquor, It is filling after inspection.

Embodiment 3

Ramulus Taxilli 20g, maple parasitism 15g, persimmon parasitism 20g, Radix Angelicae Sinensis 8g, root of bidentate achyranthes 6g, rhizome of davallia 5g, glaucocalyx rabdosia herb 5g, Kaempferia galamga 8g, dracontomelon duperreanum 12g.All 9 taste medicinal materials are taken, selected, cleaning, sterilizing, dry, chopping add rock sugar 40g, It is that 70% wine base 500g soaks 60 days with alcoholic strength, immersion gained medicated liquor filtering takes filtrate and adds water and be deployed into 1000g with rice wine, Rectification degree is 40%, and deployed medicated liquor squeezes into semi-finished product cylinder, is filtered after clarifying naturally, and the wine liquid after filtering is stored 7 days, The medicinal liquor is obtained final product, is carried out after inspection filling.

Embodiment 4

Ramulus Taxilli 30g, maple parasitism 20g, persimmon parasitism 30g, Radix Angelicae Sinensis 12g, root of bidentate achyranthes 8g, rhizome of davallia 8g, glaucocalyx rabdosia herb 8g, Kaempferia galamga 12g, dracontomelon duperreanum 18g.All 9 taste medicinal materials are taken, selected, cleaning, sterilizing, dry, chopping add rock sugar 60g, It is that 70% wine base 550kg soaks 60 days with alcoholic strength, immersion gained medicated liquor filtering takes filtrate and adds water and be deployed into 1000g with rice wine, Rectification degree is 45%, and deployed medicated liquor squeezes into semi-finished product cylinder, is filtered after clarifying naturally, and the wine liquid after filtering is stored 7 days, The medicinal liquor is obtained final product, it is filling after inspection.

Embodiment 5

Ramulus Taxilli 25g, maple parasitism 18g, persimmon parasitism 25g, Radix Angelicae Sinensis 10g, root of bidentate achyranthes 7g, rhizome of davallia 6g, glaucocalyx rabdosia herb 6g, Kaempferia galamga 10g, dracontomelon duperreanum 15g.All 9 taste medicinal materials are taken, selected, cleaning, sterilizing, dry, chopping add rock sugar 50g, It is that 70% wine base 450kg soaks 60 days with alcoholic strength, immersion gained medicated liquor filtering takes filtrate and adds water and be deployed into 1000g with rice wine, Rectification degree is 42%, and deployed medicated liquor squeezes into semi-finished product cylinder, is filtered after clarifying naturally, and the wine liquid after filtering is stored 7 days, The medicinal liquor is obtained final product, it is filling after inspection.

Clinical test

1 basic document

This group of case totally 63, wherein male 20, women 43.60 years old~85 years old age.

2 Case retrievals

2.1 Standards of Chinese Medical Syndrome Differentiation

1. ache of the spinal column；2. shin knees soreness；3. deafness and tinnitus；4. hyposexuality；5. de- tooth is sent out to shake；6. frequent micturition or enuresis nocturna frequency； 7. spontaneous perspiration, night sweat；8. chilly foul wind；9. small and weak pulse, tongue is weak or pale purple.Patient meets the above 1. 2. 3. 4. 5. standard, And possess 6. 7. 8. 9. the two of all diseases.

2.2 Western medicine diagnostic criterias

" the Chinese's sclerotin recommended using the osteoporosis committee of Aged in China association " Criteria of Osteoporosis " subject group The standard of osteoporosis suggestion diagnostic criteria (the second original text) ".With Peak Bone Mass (M ± SD) as normal reference value.＞ M ± 1SD： Normally；M ± 1~2SD：Bone amount is reduced；M ± more than 2SD：Osteoporosis；M ± more than 2SD：With at one or the fragility of many places Fracture, is serious osteoporosis；M ± more than 3SD：Without fracture, also diagnosable is serious osteoporosis.

3 treatment methods

Take the embodiment of the present invention 3 treat renal deficiency type osteoporosis medicinal liquor, each 50ml, 1 time every night, three months be one The individual course for the treatment of.

4 curative effect judging standards

Periodically patient is observed and checked, score comparing is carried out to the clinical symptoms before and after treatment, to observe curative effect of medication. Observation item：1. ache of the spinal column；2. shin knees soreness；3. spontaneous perspiration, night sweat；4. chilly is cold；5. frequent micturition or enuresis nocturna frequency.Product Point highest is divided into 15 points, minimum 0 point.

It is effective：Total mark, declines >=2/3；

Effectively：Total mark, declines >=1/3；

It is invalid：Total mark, not and above-mentioned standard.

5 the results are shown in Table 1.

Table 1 takes rear efficacy result

Clinical effectiveness shows：The medicinal liquor of present invention treatment renal deficiency type osteoporosis is to the total effective of renal deficiency type patients with osteoporosis Rate is 93.65%, is as a result shown, the present invention can improve sufferers of osteoporosis face bone mineral content, improves its quality of life, and display is good The effect for preventing and treating osteoporosis.

Model case：

Case 1：Yellow XX, female, 68 years old.Tell back pound：Pain becoming severe at night, double knees are cold, aching and limp powerless.It is usually cold, happiness Hot drink, nearly first quarter moon comes more so, pale tongue with white fur, deep thready pulse.X-ray film shows vertebral bodies of lumbar spine osteoporosis, without compression fracture sign. Diagnosis：Renal deficiency type osteoporosis.After patient drinks half course for the treatment of of the embodiment of the present invention 4, back crymodynia symptom slightly takes a turn for the better, and continues Take two courses for the treatment of, patient back crymodynia, the symptom such as weak disappears.

Although above having used general explanation, specific embodiment and experiment, the present invention is described in detail, On the basis of the present invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Cause This, these modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.

Claims (4)

1. a kind of medicinal liquor for treating renal deficiency type osteoporosis, it is characterised in that be prepared from by the raw material of following weight portion： Ramulus Taxilli 15-40 parts, 10-30 parts of maple parasitism, 15-40 parts of persimmon parasitism, Radix Angelicae Sinensis 5-15 parts, root of bidentate achyranthes 5-10 parts, bone it is broken Mend 3-10 parts, glaucocalyx rabdosia herb 3-10 parts, kaempferia galamga 5-15 parts, dracontomelon duperreanum 10-20 parts, 60-80% wine bases 400-600 Part.

2. the medicinal liquor of renal deficiency type osteoporosis is treated as claimed in claim 1, it is characterised in that be by following weight portion Raw material be prepared from：Ramulus Taxilli 20-30 parts, 15-20 parts of maple parasitism, 20-30 parts of persimmon parasitism, Radix Angelicae Sinensis 8-12 parts, Root of bidentate achyranthes 6-8 parts, rhizome of davallia 5-8 parts, glaucocalyx rabdosia herb 5-8 parts, kaempferia galamga 8-12 parts, dracontomelon duperreanum 12-18 parts, 70% wine Base 500-550 parts.

3. the medicinal liquor for the treatment of renal deficiency type osteoporosis as claimed in claim 1 or 2, it is characterised in that it be by with Lower section method is prepared from：

(1) all 9 taste medicinal materials are taken, is cleaned, sterilizes, dries, is shredded；

(2) medicinal material after shredding adds wine base to soak 50-70 days；

(3) immersion gained medicated liquor is filtered, obtains filtrate；

(4) filtrate to add water and be deployed into 800-1500 parts with rice wine, and wine degree is 30-50%；

(5) filtered after deployed medicated liquor is clarified naturally；

(6) wine liquid after filtering is stored 5-10 days, obtains final product the medicinal liquor.

4. the medicinal liquor for the treatment of renal deficiency type osteoporosis as claimed in claim 1 or 2, it is characterised in that it be by with Lower section method is prepared from：

(1) all 9 taste medicinal materials are taken, is cleaned, sterilizes, dries, is shredded；

(2) medicinal material after shredding adds rock sugar and wine base to soak 60 days；

(3) immersion gained medicated liquor is filtered, obtains filtrate；

(4) filtrate to add water and be deployed into 1000 parts with rice wine, and wine degree is 40-45%；

(5) filtered after deployed medicated liquor is clarified naturally；

(6) wine liquid after filtering is stored 7 days, obtains final product the medicinal liquor.