CN106692790A - Lung-moistening and clearing plant drink and preparation method thereof - Google Patents
Lung-moistening and clearing plant drink and preparation method thereof Download PDFInfo
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- CN106692790A CN106692790A CN201710123251.2A CN201710123251A CN106692790A CN 106692790 A CN106692790 A CN 106692790A CN 201710123251 A CN201710123251 A CN 201710123251A CN 106692790 A CN106692790 A CN 106692790A
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- almond
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
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- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Non-Alcoholic Beverages (AREA)
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Abstract
The invention provides a lung-moistening and clearing plant drink and a preparation method thereof. The lung-moistening and clearing plant drink is prepared from traditional Chinese medicinal materials, namely herba houttuyniae, rhizoma phragmitis, semen coicis, almonds, peach kernels and campanulaceae, selects the six medicinal materials in the formula, is reasonable in formula dosage, rigorous in structure and mild in medicine property, and has the efficacies of clearing away heat, reducing phlegm, dispelling stasis, expelling pus, benefiting Qi, moistening lung, nourishing stomach and tonifying spleen; the lung-moistening and clearing plant drink is very suitable for being prepared into a plant drink, is original in flavor, free from any additive, pure in taste, pleasant and palatable, can improve human autoimmune functions when being frequently drunk and has the efficacies of cleaning and nourishing a human body respiratory system.
Description
Technical field
The invention belongs to field of health care food, and in particular to a kind of plant beverage of clearing lung-heat moistening lung and preparation method thereof.
Background technology
Haze is the general designation of mist and haze, and haze is that the pollutant of a large amount of anthropogenic discharges is assembled under specific meteorological condition and made
Into.The fine particle (particulate matter of the particle diameter less than or equal to 2.5 microns, referred to as PM2.5) or Aerosol Pollution of high concentration
It is the basic reason of haze.
Because the aerodynamic size of PM2.5 fine particles is small and specific surface area is big, portable big capacity industrial waste gas, wave
The poisonous and harmful substances such as hair property chemical substance, motor-vehicle tail-gas, Human Lung is entered through the filtration of vibrissa through respiratory tract
Tissue depth and blood circulation, serious harm is produced to health.Atmospheric particulates into respiratory tract are by stimulation and corruption
Erosion alveolar wall, destroys respiratory tract defensive barrier, makes impaired lung function, causes pneumonia, chronic bronchitis, chronic obstructive pulmonary
The incidence of disease of disease, bronchial astehma etc. increases, the Respiratory symptoms such as patient cough, expectoration occurs, pants.Epidemiology statistics
Display：With increasing for Atmospheric Particulate Matter concentration, the occurrence rate of respiratory symptom, insufficiency of pulmonary function, cardiorespiratory system disease
Morbidity and mortality significantly rise, and the two has direct correlation, and it is constantly elevated that PM2.5 has turned into the respiratory system incidence of disease
Important factor in order.
In addition, the problems that smoking in recent years causes have become a problem for social extensive concern, according to the world
Health organization is investigated, there is the cancer person of a quarter in the country of industry prosperity, and smoking accounts for 90%；Die from bronchitis
, smoking accounts for 75%；And also most crowd is just subject the harm of second-hand-cigarette, therefore, how to reduce and mitigate because
Harm and the health problem of raising smoking population that haze brings to the mankind, its tool are of great significance.
The content of the invention
To solve the above problems, the invention provides a kind of plant beverage of clearing lung-heat moistening lung, by weight, its feature exists
In：By cordate houttuynia 10-36 parts, reed rhizome 6-18 parts, coix seed 6-18 parts, almond 5-13 parts, peach kernel 5-13 parts, balloonflower root 6-18 parts of system
Into.
Specifically：The invention provides a kind of plant beverage of clearing lung-heat moistening lung, by weight, it is characterised in that：By fish
14-22 parts of raw meat grass, reed rhizome 10-14 parts, coix seed 10-14 parts, almond 7-11 parts, peach kernel 7-11 parts, balloonflower root 10-14 parts be made.
Moisten the plant beverage of spleen and lung according to a kind of clear smaze described above, white sand can also be added according to mouthfeel needs
Sugar, sucrose and sweetener one or more be mixed and made into various drinks.
Present invention also offers a kind of preparation method of the plant beverage of clear smaze profit spleen and lung, comprise the following steps：
(1) cordate houttuynia of formula ratio, reed rhizome, coix seed, balloonflower root are weighed to be put into extractor, then weighs the warp of formula ratio and broken
Almond, peach kernel after skin are added in extractor, and medicinal material is well mixed, the hot water for adding 15-20 times of medicinal material to measure；
(2) it is 90-100 DEG C to control extraction temperature, and constant temperature extracting 30-120min, extract is collected standby through filtering；
(3) white granulated sugar of beverage total amount 3%-5% is weighed, hot water dissolving in adding the extract of step (2), constant volume, fills
Nitrogen, filling, sterilizing, that is, obtain plant beverage of the present invention.
Preferably, cordate houttuynia, reed rhizome, coix seed, balloonflower root are crushed to granularity for 0.25-0.5mm in the step (1), apricot
Benevolence, peach kernel are crushed to granularity for 0.5-0.8mm, and hot water temperature is 80-90 DEG C.
Extraction temperature is 95-100 DEG C, constant temperature extracting 50-70min in the step (2).
Medicinal material immersion 60-120min before extraction in the step (2).
Hot water temperature is 80-90 DEG C in the step (3), and filling temperature is 70-80 DEG C, 121 DEG C of sterilizing 15-20min.
Specifically, according to the preparation method of plant beverage described above, comprise the following steps：
(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.35-0.45mm, is put into and is carried
In taking tank, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.6-0.7mm, in adding extractor,
Medicinal material is well mixed, and adds the hot water of measure 85-90 DEG C of 15-20 times of medicinal material；
(2) constant temperature immersion 60-90min, heats up, and it is 95-100 DEG C to control extraction temperature, constant temperature extracting 50-70min, extraction
Liquid is collected standby through filtering；
(3) white granulated sugar of beverage total amount 4% is weighed, with 80-85 DEG C of hot water dissolving, step (2) extract is added, constant volume,
Nitrogen charging, 70-75 DEG C filling, 121 DEG C of sterilizing 20min, that is, obtain plant beverage of the present invention.
Principle of the invention and beneficial effect are：
First, the present invention is to carry out drug efficacy study and technical study process to SUN Si miao classics recipe " Phragmitis decoction "
In, it is found that its drug effect is not notable enough, drug effect is worked slowly, and the collocation again of primary and secondary medication is carried out for this, is sieved by multiple formula
Choosing, is square medicine with cordate houttuynia, reed rhizome, coix seed, almond, peach kernel, balloonflower root；Cordate houttuynia is monarch drug in a prescription in side, and lung-heat clearing and detoxification was both clear sharp
Lung Qi obstruction caused by haze, dredges the respectful drop of profit lung to strengthen lung power again, therefore consumption is maximum；Sweet frivolous, the return lung of trembling with fear of reed rhizome
Stomach, is apt to clearing lung-heat heat, and promoting production of body fluid and nourishing the lung, lung preferring moisture to dryness, and the work(that lung must moisten then a surname's drop can be more；Coix seed it is sweet it is light be slightly cold, on
Clearing lung-heat heat and apocenosis, lower sharp stomach and excreting dampness, the two common principal drug assistance clearing away heat and eliminating pus is ministerial drug；Almond, peach kernel are relieving cough and asthma, moisten again
Intestines defaecation, activate blood circulation and disperse blood clots, qi and blood must be logical, then from flat, the two common principal drug assistance is adjutant to visceral-qi；Balloonflower root taste is pungent, hardship, return lung stomach,
Relieving sore-throat eliminating the phlegm, facilitaing lung apocenosis, and can declare, can dissipate, carry all medicines and float, draw and be attributed to lung to make medicine.In a word, six medicines, Jun Chenzuo in side
Make, it is of a tightly knit structure, mild in medicine property and, have the effect of clearing heat and detoxicating facilitaing lung apocenosis altogether.Its drug effect be significantly better than " Phragmitis decoction " and its
Face its other party medicine of card plus-minus, party's medicinal material uses the dual-purpose medicinal material of food materials, and the property of thing of getting it filled, with the taste of food, is eaten and borrows the efficacy of a drug,
Medicine helps food prestige, and with food in one, it is both medicine and effect of food to give full play to residence medicine, is particularly suitable for being made plant drink
Material, genuine, without any additive, pure taste, pleasant agreeable to the taste, long-term storage is never degenerated under normal temperature state.Often
Drink, human autoimmune's function can be improved, and have functions that to clear up and nourish human respiratory.
Secondly, the present invention controls constant temperature Extracting temperature for 90-100 DEG C, and its extract can preferably be enriched with effective component fish
Raw meat grass element, glycerol trioleate etc., have functions that significant clearing heat and detoxicating, facilitaing lung apocenosis, and entirely extraction, constant volume,
The high temperature that 70 DEG C are remained above in filling technical process is operated, and can avoid introducing the infection of alien bacteria, the peace of product
Full property can more be guaranteed.
Preferably to illustrate beneficial effects of the present invention, the present invention has also listed following test example, it is intended to illustrate this hair
Bright beneficial effect, but it is by no means limited to protection scope of the present invention.
First, pharmacodynamic study
The protective effect research that respiratory system in rats caused by the air fine particles of experimental example 1 is damaged
Experimental technique
1.1 experimental animals
SD rats, SPF grades.Totally 90, male and female half and half, 6~8 week old, 180~200g of body weight when animal is ordered.
1.2 experimental animal feeding standards and packet
Laboratory Animal Facility persistently keeps barrier environment standard.The control range of main environment index：20~26 DEG C of room temperature,
Temperature difference per day≤4 DEG C.Relative humidity 40~70%.Time/hour of minimum air changes 15, optical illumination：Secretly=12h：12h.Animal is raised
Support in polypropylene rat group support box, cage tool specification is：545*395*200mm3, per 3~5, box, during its cultured space meets
Regulation on minimum space needed for experimental animal in magnificent people's republic's standard GB/T 14925-2010.All animals by
The qualified personnel of training carry out feeding and management.1 bedding and padding and cage tool are changed weekly.Daily addition mouse special feed is eaten for animal
With, separately drunk for animal using drinking bottle fill water, animal diet followed freedom of movement is kept in whole feeding process.That newly receives is dynamic
Quality testing epidemic disease 5~7 days, confirms that animal health is disease-free, can use.
It is grouped by the stratified random method of dividision into groups according to the weight of animals；Female animals are grouped respectively：
Control group (control)：10 rats, daily snout is empty exposed to the Inhalation device suction cleaning of cleaning
Gas 30min；Model group (model)：10 rats, daily snout is exposed to air fine particles aerosol contamination device, inhales
Enter Air haze 30min；Test group 1-7：10 rats, male and female half and half.Daily snout is molten exposed to air fine particles gas
Glue contamination device, suction Air haze 30min；The preceding 1 hour gavage of contamination gives the liquid of 1ml/100g, test group administrations
It is as follows：
Test group 1：Give " Phragmitis decoction " (formula：Reed stem 60g, melon valve 30g, coix seed 9g, peach kernel 24g)；
Test group 2：Give inventive formulation cordate houttuynia 30g, reed rhizome 45g, balloonflower root 8g, almond 7g, coix seed 20g, peach kernel
Liquid obtained in 9g；
Test group 3：Cordate houttuynia 12g, reed rhizome 12g, balloonflower root 8g, coix seed 8g, liquid obtained in peach kernel 9g；
Test group 4：Cordate houttuynia 30g, reed rhizome 30g, almond 8g, coix seed 9g, liquid obtained in peach kernel 9g；
Test group 5：Reed rhizome 60g, balloonflower root 8g, almond 8g, coix seed 9g, liquid obtained in peach kernel 9g；
Experimental group 6：The holy former breath gold that relaxes drinks happily cordate houttuynia almond solid beverage, and (formula is：Cordate houttuynia, coix seed, waxgourd seed,
Malt, almond, peach kernel, Poria cocos；Produced by the side pharmaceutical Co. Ltd of Guangzhou one)
(contaminated by HOPE-MED dust-like mouth and nose dynamic formula and set by continuous 8 weeks suction air fine particles of SD rats
It is standby, set up haze environment), gavage gives drug solution while contamination carries out pharmaceutical intervention, in terms of body weight, PFT etc.
Research, investigates and evaluates the anti-fog haze effect of Chinese medicinal plant beverage of the present invention.
Experimental result
1st, Growth in Rats evaluating characteristics：
(contaminated by HOPE-MED dust-like mouth and nose dynamic formula through by continuous 8 weeks suction air fine particles of SD rats
Equipment, sets up haze environment), gavage gives drug solution while contamination carries out pharmaceutical intervention, observation 1 time daily, every time
Animal weather is not observed after contamination, continuous contamination is measured after 8 weeks to Mouse Weight, its result such as table 1 below：
Table 1：Continuous 8 weeks suction air fine particles body weight determinations of SD rats
| Group | Body weight (g) before experiment | Body weight (g) after contamination in 8 weeks | Body weight increase amount (g) |
| Control group | 189.5±8.3 | 220.5±9.1 | 31.0±2.1 |
| Model group | 190.6±8.1 | 200.7±10.1 | 10.1±1.8 |
| Test group 1 | 188.3±8.3 | 204.3±13.3 | 16.0±1.9 |
| Test group 2 | 191.4±7.5 | 218.6±12.5 | 27.4±2.5 |
| Test group 3 | 189.7±8.7 | 206.1±13.7 | 16.4±2.2 |
| Test group 4 | 190.5±7.9 | 205.2±11.9 | 15.1±1.7 |
| Test group 5 | 189.2±8.3 | 207.1±12.3 | 17.9±2.3 |
| Test group 6 | 190.4±8.2 | 206.5±11.3 | 16.1±1.3 |
Result of the test table：Contamination animal each group body weight increase is slower than control group.Test group 1-6 administrations are intervened, and can have
Effect improves SD rats and sucks within continuous 8 weeks influence of the air fine particles to animal growth, wherein, test group 2 employs this
The prescription administration for determining is invented, its effect is the most notable, the continuous 8 weeks growth and development states of suction air fine particles of SD rats
Close to Normal group, illustrate present invention determine that medicament composing prescription can significantly improve under haze environment to rat weather
Influence.
2nd, the evaluation of rats breathing function：
The measure of Conscious Rat PFT is carried out using EMKA animal lung functions monitoring system, by EMKA animal lung functions prison
Examining system is positioned in quiet laboratory, it is formal determine before system compensation, demarcate, ventilation, data acquiring frequency be every five seconds for example from
Dynamic collection is once, per minute to show a measurement result.Rat is put into all bodies and retouches meter case endoadaptation 5-10min, record 3-
8min, using every average of the result of animal as this animal lung function measurement result.Testing index includes inspiratory duration
(Ti), expiratory duration (Te), tidal volume (TV), expiration amount (EV), relaxation time (RT), throughput per minute (MV).
Determine an animal breath function within every 2 weeks during exposed rats, rat is put into all plethysmography box, even
Connect determination of respiratory function instrument to be measured, the results are shown in Table 2.
Table 2：Continuous Inhalation SD rats breathing functional examinations：
Test result analysis：
The Ti values of model group rats Inhalation are apparently higher than control group (p<0.05), contamination SD rats RT apparently higher than
Control group (p<0.05), illustrate after the model group rats lung function index related to flow and capacity is received and significantly inhibited,
Animal must could maintain the PFT of relative needs by extending expiratory duration and relaxation time.Model group rats TV, EV and
MV has different degrees of reduction during observing, and illustrates that the cubical content of breathing is decreased obviously, and pulmonary ventilation function storage level also drops
It is low.And test group 1-6 compares with model group, can be obviously improved improves the pulmonary function damage that continuous suction fine particle is caused
Wound, tool has some improvement.And using test group 2 present invention determine that prescription administration intervene, it improves continuous suction
Contamination SD rats breathing functional effects are the most notable, and it improves continuous contamination SD rats breathing functions close to Normal group,
Other test groups are substantially better than, therefore, illustrate present invention determine that Chinese prescription can significantly improve mist with prominent drug activity
The damage that haze is caused to respiratory system.
Test example 2：Obtained clearing lung-heat moistening lung plant beverage clinical tests of the invention
Experimental subjects：There is pharyngeal uncomfortable, dry cough symptom in Beijing, altogether in haze high-incidence season in winter, frequent outdoor study
180.
Experimental technique：Experimental subjects is divided into test group 1-5 and control group, every group of 30 people；
Test group A1-A6：The clearing lung-heat moistening lung plant beverage that embodiment of the present invention 1-6 is prepared tasks A1-A5 successively
The experimental subjects of group is taken, and instructions of taking is：1 bottle (310ml), daily 2 times, continuously takes 7 days every time；
Normal group：Only take drinking water.
Experimental result is shown in Table 3.
Table 3：Obtained clearing lung-heat moistening lung plant beverage clinical tests situation table of the invention
Result of the test shows:Normal group, after 7 days, only 4 people that expression is clearly better, 6 people alleviated, without bright
Aobvious also 20 people for taking a turn for the better, and test group A2-A5 (the obtained plant beverage of the present invention), after taking the 7th day, symptom is clearly better
Number up to 16~23 people；The number 7-12 people alleviated, 0 people without positive effect, and test group A3 best results, disease
Shape is clearly better number up to 23 people；The people of number 7 alleviated, 0 people without positive effect, it can be seen that, it is of the present invention
Plant beverage has obvious curative effect to symptoms such as pharyngeal discomfort, dry cough.And it is preferred that cordate houttuynia 10-36 parts, reed rhizome 6-18 parts,
Balloonflower root 6-18 parts, almond 5-13g parts, coix seed 6-18 parts, peach kernel 5-13 parts of its formula curative effect it is optimal, it is more reasonable to be formulated.
Test example 3：Obtained clearing lung-heat moistening lung plant beverage of the invention is to improving the uncomfortable investigation of respiratory tract that smoking causes：
Subjects：Smoking often had pharyngeal discomfort more than 3 years, retched, the people of smoker 120 of the symptom such as abundant expectoration.
Experimental technique：Experimental subjects is divided into test group 1-3 and control group, every group of 20 people；
Test group 1：Take ancient prescription " Phragmitis decoction " daily；
Test group 2：The commercially available holy former breath gold that relaxes is drunk happily cordate houttuynia almond solid beverage and (is given birth to by the side pharmaceutical Co. Ltd of Guangzhou one
Produce)；
Test group 3：Obtained clearing lung-heat moistening lung plant beverage of the invention；
Instructions of taking is：Each 310ml, daily 2 times, continuously takes 7 days；
Normal group：Only take drinking water.
Experimental result is shown in Table 4.
Table 4：Obtained clearing lung-heat moistening lung plant beverage of the invention is to improving the uncomfortable investigation of respiratory tract that smoking causes：
Result of the test shows：Normal group, after 7 days, only 5 people that expression is clearly better, 5 people alleviated, without bright
Aobvious also 20 people for taking a turn for the better；And the obtained clearing lung-heat moistening lung plant beverage of the present invention, only 22 people that expression is clearly better, alleviate
7 people, without being clearly better only 1 people；And test group 1 and test group 2 are substantially better than, it is indicated above that clearing lung-heat of the present invention is moistened
Lung beverage causes the symptoms such as the pharyngeal discomfort of respiratory tract, retch, abundant expectoration to have obvious curative effect to smoking.
2nd, technical study
1st, extracting mode screening：The present invention during technical study is carried out, to maximally utilise the work of each medicine
Property composition, respectively to water boiling and extraction, alcohol reflux extract, ethanol percolation extract etc. mode investigate, as a result show, use
The mode of high temperature water extraction, not only the active component extraction efficiency of the formula herbs is high, the content of decanoy acetaldehyde, amarogentin etc.
Height, leachable is more, and the mode boiled of decocting is more suitable for the production of beverage, it is to avoid shadow of the non-solvent drunk to Product Safety
Ring, also more economically.The factor such as production time, production cost in the comprehensive big production of batch, when further to Extracting temperature, extraction
Between investigated.
Carried by using 5 thermogrades (70-80 DEG C, 80-90 DEG C, 90-95 DEG C, 95-100 DEG C, 90-100 DEG C), 4
Taking the time period (30-60min, 60-120min, 90-180min, 30-120min) is investigated, and is as a result shown, when using 90-
At a temperature of 100 DEG C constant temperature extract 30-120min when, its extract solution more can rich poly- active constituents of medicine, by detection, decanoy acetaldehyde
Content >=0.04% crude drug, glycerol trioleate content >=0.65% crude drug, amarogentin content >=7.2% crude drug, total leaching
Thing >=50% crude drug, plays maximum drug effect.Wherein, heat-insulation soaking 60-120min, constant temperature, at 95-100 DEG C, are imitated before extraction
Fruit is optimal, and not only active component content is preferable, can also shorten extraction time for 50-70min.Due to soaking in advance, high temperature is carried
The double action for taking, effectively shortens extraction time, is very useful to a large amount of productions.
2nd, subsequent technique research：Found in research process, in follow-up auxiliary material addition, constant volume and filling stage, lasting guarantor
Process temperature is held for 70-90 DEG C, is heated up when not only contributing to avoid subsequent high temperature from sterilizing and is caused process time extension, production cost
The inconvenience such as increase, it is often more important that in whole production link, persistently keep the operation of higher temperature, can avoid introducing external thin
The infection of bacterium, makes the security of product be guaranteed.
3rd, raw material grinding particle size screening：When extracting, it is crushed or dissolution to active ingredient of degree of crushing raw medicinal material
Have a significant impact, we have found almond, peach kernel due to containing oil components under study for action, its grinding particle size is excessive to be unfavorable for activity
The dissolution of composition, cross detailed rules and regulations causes the part of oily matter to be oozed out due to broken, causes to be increased during water extraction it to reed
The medicinal materials such as root, balloonflower root and the bonding of itself and influence, while the degree of grinding of the medicinal material such as cordate houttuynia will also consider almond etc.
Particle size after cracking, makes both reach balance and is just conducive to extracting, and the present invention is crushed to granularity for 0.5- by by peach kernel, almond
0.8mm, cordate houttuynia etc. crush 0.25-0.5mm, be difficult between medicinal material bond it is agglomerating, its extract active component it is in hgher efficiency.
To sum up, preparation technology obtained from the present invention is preferred, its technique is very simple, it is easy to operates, and can save production
Cost, improve production efficiency.And plant extract efficiency high, more can rich poly- active constituents of medicine, can more play maximum drug effect.
Specific embodiment：
Embodiment 1：Clearing lung-heat moistening lung plant beverage (low component)
Formula：Cordate houttuynia 8g, reed rhizome 4g, coix seed 5g, almond 4g, peach kernel 4g, balloonflower root 5g
Preparation method：(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.25mm, is put into and is carried
In taking tank, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.5mm, in adding extractor, medicinal material
It is well mixed, add the hot water of 15 times 90 DEG C of amount of medicinal material；
(2) constant temperature immersion 60min, heats up, and control extraction temperature for 90 DEG C, constant temperature extracting 80min, extract through filtering,
Collect standby；
(3) white granulated sugar of beverage total amount 3% is weighed, with 80 DEG C of hot water dissolvings, step (2) extract is added, is settled to
2000ml, nitrogen charging, 70 DEG C are filling, 121 DEG C of sterilizing 18min, that is, obtain plant beverage of the present invention.
Embodiment 2：Clearing lung-heat moistening lung plant beverage
Formula：Cordate houttuynia 10g, reed rhizome 6g, coix seed 6g, almond 5g, peach kernel 5g, balloonflower root 6g
Preparation method：(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.5mm, is put into and is carried
In taking tank, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.8mm, in adding extractor, medicinal material
It is well mixed, add the hot water of 20 times 80 DEG C of amount of medicinal material；
(2) constant temperature immersion 120min, heats up, and it is 100 DEG C to control extraction temperature, and constant temperature extracting 30min, extract passes through
Filter, collects standby；
(3) white granulated sugar of beverage total amount 5% is weighed, with 90 DEG C of hot water dissolvings, step (2) extract is added, is settled to
2000ml, nitrogen charging, 80 DEG C are filling, 121 DEG C of sterilizing 15min, that is, obtain plant beverage of the present invention.
Embodiment 3：Clearing lung-heat moistening lung plant beverage
Formula：Cordate houttuynia 14g, reed rhizome 10g, coix seed 10g, almond 7g, peach kernel 7g, balloonflower root 10g
Preparation method：(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.35mm, is put into and is carried
In taking tank, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.6mm, in adding extractor, medicinal material
It is well mixed, add the hot water of 18 times 85 DEG C of amount of medicinal material；
(2) constant temperature immersion 90min, heats up, and control extraction temperature for 100 DEG C, constant temperature extracting 50min, extract through filtering,
Collect standby；
(3) white granulated sugar of beverage total amount 5% is weighed, with 90 DEG C of hot water dissolvings, step (2) extract is added, is settled to
2000ml, nitrogen charging, 75 DEG C are filling, 121 DEG C of sterilizing 20min, that is, obtain plant beverage of the present invention.
Embodiment 4：Clearing lung-heat moistening lung plant beverage
Formula：Cordate houttuynia 22g, reed rhizome 14g, coix seed 14g, almond 11g, peach kernel 11g, balloonflower root 12g
Preparation method：(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.45mm, is put into and is carried
In taking tank, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.7mm, in adding extractor, medicinal material
It is well mixed, add the hot water of 16 times 85 DEG C of amount of medicinal material；
(2) constant temperature immersion 100min, heats up, and control extraction temperature for 95 DEG C, constant temperature extracting 70min, extract through filtering,
Collect standby；
(3) white granulated sugar of beverage total amount 4% is weighed, with 85 DEG C of hot water dissolvings, step (2) extract is added, is settled to
2000ml, nitrogen charging, 75 DEG C are filling, 121 DEG C of sterilizing 18min, that is, obtain plant beverage of the present invention.
Embodiment 5：Clearing lung-heat moistening lung plant beverage
Formula：Cordate houttuynia 36g, reed rhizome 18g, coix seed 18g, almond 13g, peach kernel 11g, balloonflower root 18g
Preparation method：(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.45mm, is put into and is carried
In taking tank, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.7mm, in adding extractor, medicinal material
It is well mixed, add the hot water of 20 times 95 DEG C of amount of medicinal material；
(2) constant temperature immersion 80min, heats up, and it is 100 DEG C to control extraction temperature, and constant temperature extracting 120min, extract passes through
Filter, collects standby；
(3) white granulated sugar of beverage total amount 3% is weighed, with 90 DEG C of hot water dissolvings, step (2) extract is added, is settled to
2000ml, nitrogen charging, 80 DEG C are filling, 121 DEG C of sterilizing 20min, that is, obtain plant beverage of the present invention.
Embodiment 6：Clearing lung-heat moistening lung plant beverage (component high)
Formula：Cordate houttuynia 38g, reed rhizome 20g, coix seed 20g, almond 14g, peach kernel 14g, balloonflower root 20g
Preparation method：(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.5mm, is put into and is carried
In taking tank, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.8mm, in adding extractor, medicinal material
It is well mixed, add the hot water of 20 times 95 DEG C of amount of medicinal material；
(2) constant temperature immersion 90min, heats up, and control extraction temperature for 100 DEG C, constant temperature extracting 90min, extract through filtering,
Collect standby；
(3) white granulated sugar of beverage total amount 5% is weighed, with 95 DEG C of hot water dissolvings, step (2) extract is added, is settled to
2000ml, nitrogen charging, 80 DEG C are filling, 121 DEG C of sterilizing 20min, that is, obtain plant beverage of the present invention.
Claims (9)
1. a kind of plant beverage of clearing lung-heat moistening lung, by weight, it is characterised in that：By cordate houttuynia 10-36 parts, reed rhizome 6-18
Part, coix seed 6-18 parts, almond 5-13 parts, peach kernel 5-13 parts, balloonflower root 6-18 parts be made.
2. the plant beverage of a kind of clearing lung-heat moistening lung according to claim 1, by weight, it is characterised in that：By fish raw meat
It is careless 14-22 parts, reed rhizome 10-14 parts, coix seed 10-14 parts, almond 7-11 parts, peach kernel 7-11 parts, balloonflower root 10-14 parts be made.
3. a kind of plant beverage of clearing lung-heat moistening lung according to claim 1 and 2, can add white granulated sugar, sucrose and flavor enhancement
One or more are mixed and made into the drink of different taste.
4. a kind of preparation method of the plant beverage of clearing lung-heat moistening lung, it is characterised in that：Comprise the following steps：
(1) cordate houttuynia of formula ratio, reed rhizome, coix seed, balloonflower root is weighed to be put into extractor, then weigh formula ratio after broken skin
Almond, during peach kernel adds extractor, medicinal material is well mixed, and adds the hot water measured of 15-20 times of medicinal material；
(2) it is 90-100 DEG C to control extraction temperature, and constant temperature extracting 30-120min, extract is collected standby through filtering；
(3) weigh the white granulated sugar of beverage total amount 3%-5%, hot water dissolving, in adding the extract of step (2), constant volume, nitrogen charging,
Filling, sterilizing, that is, obtain plant beverage of the present invention.
5. the preparation method of the plant beverage of a kind of clearing lung-heat moistening lung according to claim 4, it is characterised in that：The step
(1) cordate houttuynia, reed rhizome, coix seed, balloonflower root are crushed to granularity for 0.25-0.5mm in, and almond, peach kernel are crushed to granularity for 0.5-
0.8mm, hot water temperature is 80-90 DEG C.
6. the preparation method of the plant beverage of a kind of clearing lung-heat moistening lung according to claim 4, it is characterised in that：The step
(2) extraction temperature is 95-100 DEG C, constant temperature extracting 50-70min in.
7. the preparation method of the plant beverage of a kind of clearing lung-heat moistening lung according to claim 4, it is characterised in that：The step
(2) medicinal material immersion 60-120min before extraction in.
8. the preparation method of the plant beverage of a kind of clearing lung-heat moistening lung according to claim 4, it is characterised in that：The step
(3) hot water temperature is 80-90 DEG C in, and filling temperature is 70-80 DEG C, 121 DEG C of sterilizing 15-20min.
9. the preparation method of the plant beverage of a kind of clearing lung-heat moistening lung according to claim 4, it is characterised in that：Including following
Step：
(1) cordate houttuynia, reed rhizome, coix seed, the balloonflower root of the amount are weighed, granularity is crushed to for 0.35-0.45mm, extractor is put into
In, then weigh the amount through the almond after broken skin, peach kernel, be crushed to granularity for 0.6-0.7mm, in adding extractor, medicinal material
It is well mixed, the hot water of add that 15-20 times of medicinal material measures 85-90 DEG C；
(2) constant temperature immersion 60-90min, heats up, and it is 95-100 DEG C to control extraction temperature, constant temperature extracting 50-70min, extract warp
Filtering, collects standby；
(3) white granulated sugar of beverage total amount 4% is weighed, with 80-85 DEG C of hot water dissolving, step (2) extract is added, constant volume, nitrogen charging,
70-75 DEG C filling, 121 DEG C of sterilizing 20min, that is, obtain plant beverage of the present invention.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710123251.2A CN106692790B (en) | 2017-03-03 | 2017-03-03 | Plant beverage capable of moistening lung and clearing lung and preparation method thereof |
Applications Claiming Priority (1)
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| CN201710123251.2A CN106692790B (en) | 2017-03-03 | 2017-03-03 | Plant beverage capable of moistening lung and clearing lung and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107296191A (en) * | 2017-07-12 | 2017-10-27 | 润己饮料（河源）有限公司 | The formula and its manufacture craft of a kind of cordate houttuynia plant beverage |
| CN107455627A (en) * | 2017-07-31 | 2017-12-12 | 贵州盛达生植物发展有限公司 | A kind of dendrobium candidum plant beverage and preparation method thereof |
| CN107568554A (en) * | 2017-09-30 | 2018-01-12 | 朱昱光 | A kind of solid beverage |
| CN108721425A (en) * | 2018-06-12 | 2018-11-02 | 天津市中科众晟医疗科技有限责任公司 | Cream and preparation method thereof is applied at a kind of acupuncture point of prevention haze clearing lung-heat |
| CN113499400A (en) * | 2021-06-18 | 2021-10-15 | 建昌帮药业有限公司 | Traditional Chinese medicine composition and preparation method and application thereof |
| CN118160921A (en) * | 2024-04-19 | 2024-06-11 | 馨辰生物(广东)有限公司 | Lung-protecting composition and lung-protecting beverage |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107296191A (en) * | 2017-07-12 | 2017-10-27 | 润己饮料（河源）有限公司 | The formula and its manufacture craft of a kind of cordate houttuynia plant beverage |
| CN107455627A (en) * | 2017-07-31 | 2017-12-12 | 贵州盛达生植物发展有限公司 | A kind of dendrobium candidum plant beverage and preparation method thereof |
| CN107568554A (en) * | 2017-09-30 | 2018-01-12 | 朱昱光 | A kind of solid beverage |
| CN108721425A (en) * | 2018-06-12 | 2018-11-02 | 天津市中科众晟医疗科技有限责任公司 | Cream and preparation method thereof is applied at a kind of acupuncture point of prevention haze clearing lung-heat |
| CN108721425B (en) * | 2018-06-12 | 2021-06-04 | 天津市中科众晟医疗科技有限责任公司 | Lung-clearing acupoint application paste and preparation method thereof |
| CN113499400A (en) * | 2021-06-18 | 2021-10-15 | 建昌帮药业有限公司 | Traditional Chinese medicine composition and preparation method and application thereof |
| CN118160921A (en) * | 2024-04-19 | 2024-06-11 | 馨辰生物(广东)有限公司 | Lung-protecting composition and lung-protecting beverage |
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Address after: No.1 Changqing Road, Shangba Industrial Park, Daozhen Autonomous County, Zunyi City, Guizhou Province Applicant after: GUIZHOU EVERGREEN PHARMACEUTICAL Co.,Ltd. Address before: 563500 Guizhou city in Zunyi Province, Daozhen yilao and Miao Autonomous County Xintian Village Center BA Xiang Group Applicant before: GUIZHOU EVERGREEN PHARMACEUTICAL Co.,Ltd. |
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