CN106692790B - Plant beverage capable of moistening lung and clearing lung and preparation method thereof - Google Patents
Plant beverage capable of moistening lung and clearing lung and preparation method thereof Download PDFInfo
- Publication number
- CN106692790B CN106692790B CN201710123251.2A CN201710123251A CN106692790B CN 106692790 B CN106692790 B CN 106692790B CN 201710123251 A CN201710123251 A CN 201710123251A CN 106692790 B CN106692790 B CN 106692790B
- Authority
- CN
- China
- Prior art keywords
- lung
- plant beverage
- clearing
- beverage
- moistening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 235000013361 beverage Nutrition 0.000 title claims abstract description 65
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 210000004072 lung Anatomy 0.000 title claims description 39
- 241000196324 Embryophyta Species 0.000 claims abstract description 49
- 244000144725 Amygdalus communis Species 0.000 claims abstract description 35
- 235000020224 almond Nutrition 0.000 claims abstract description 35
- 239000003814 drug Substances 0.000 claims abstract description 35
- 235000011437 Amygdalus communis Nutrition 0.000 claims abstract description 34
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 34
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 34
- 240000000691 Houttuynia cordata Species 0.000 claims abstract description 32
- 230000000694 effects Effects 0.000 claims abstract description 25
- 239000000463 material Substances 0.000 claims abstract description 23
- 210000002345 respiratory system Anatomy 0.000 claims abstract description 12
- 235000006753 Platycodon grandiflorum Nutrition 0.000 claims abstract description 10
- 235000019640 taste Nutrition 0.000 claims abstract description 10
- 235000013719 Houttuynia cordata Nutrition 0.000 claims abstract description 9
- 210000000582 semen Anatomy 0.000 claims abstract description 7
- 244000274050 Platycodon grandiflorum Species 0.000 claims abstract 5
- 238000000605 extraction Methods 0.000 claims description 52
- 235000014676 Phragmites communis Nutrition 0.000 claims description 32
- 244000077995 Coix lacryma jobi Species 0.000 claims description 31
- 238000005303 weighing Methods 0.000 claims description 30
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 27
- 235000013717 Houttuynia Nutrition 0.000 claims description 23
- 238000011049 filling Methods 0.000 claims description 23
- 241000758794 Asarum Species 0.000 claims description 21
- 235000021552 granulated sugar Nutrition 0.000 claims description 21
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 20
- 235000006751 Platycodon Nutrition 0.000 claims description 19
- 229930189914 platycodon Natural products 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 17
- 230000001954 sterilising effect Effects 0.000 claims description 13
- 238000002791 soaking Methods 0.000 claims description 12
- 238000001914 filtration Methods 0.000 claims description 11
- 238000002156 mixing Methods 0.000 claims description 10
- 229910052757 nitrogen Inorganic materials 0.000 claims description 10
- 238000010438 heat treatment Methods 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 9
- 230000006378 damage Effects 0.000 claims description 8
- 230000000391 smoking effect Effects 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 5
- 229930006000 Sucrose Natural products 0.000 claims description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
- 239000002243 precursor Substances 0.000 claims description 2
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 2
- 238000004659 sterilization and disinfection Methods 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims 2
- 239000005720 sucrose Substances 0.000 claims 1
- 241000282414 Homo sapiens Species 0.000 abstract description 5
- 206010062717 Increased upper airway secretion Diseases 0.000 abstract description 4
- 239000008280 blood Substances 0.000 abstract description 4
- 210000004369 blood Anatomy 0.000 abstract description 4
- 208000026435 phlegm Diseases 0.000 abstract description 4
- 239000000654 additive Substances 0.000 abstract description 2
- 230000000996 additive effect Effects 0.000 abstract description 2
- 238000004140 cleaning Methods 0.000 abstract description 2
- 239000000796 flavoring agent Substances 0.000 abstract description 2
- 235000019634 flavors Nutrition 0.000 abstract description 2
- 230000001363 autoimmune Effects 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 36
- 241000700159 Rattus Species 0.000 description 27
- 241001465754 Metazoa Species 0.000 description 26
- 241000357613 Platycodon Species 0.000 description 16
- 229940079593 drug Drugs 0.000 description 16
- 238000004519 manufacturing process Methods 0.000 description 9
- 240000003582 Platycodon grandiflorus Species 0.000 description 8
- 230000004199 lung function Effects 0.000 description 8
- 230000008569 process Effects 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 8
- 239000004480 active ingredient Substances 0.000 description 7
- 231100000167 toxic agent Toxicity 0.000 description 7
- 239000003440 toxic substance Substances 0.000 description 7
- 235000013305 food Nutrition 0.000 description 6
- 230000004202 respiratory function Effects 0.000 description 6
- 238000002474 experimental method Methods 0.000 description 5
- 230000006872 improvement Effects 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 206010011224 Cough Diseases 0.000 description 4
- 241000721047 Danaus plexippus Species 0.000 description 4
- QBDCOUHKEVYWLO-UHFFFAOYSA-N Decanoyl acetaldehyde Chemical compound CCCCCCCCCC(=O)CC=O QBDCOUHKEVYWLO-UHFFFAOYSA-N 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 244000273256 Phragmites communis Species 0.000 description 4
- 238000011109 contamination Methods 0.000 description 4
- 230000003203 everyday effect Effects 0.000 description 4
- 239000010419 fine particle Substances 0.000 description 4
- 230000003285 pharmacodynamic effect Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000000443 aerosol Substances 0.000 description 3
- 238000010171 animal model Methods 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 230000002354 daily effect Effects 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 239000003651 drinking water Substances 0.000 description 3
- 235000020188 drinking water Nutrition 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 208000015181 infectious disease Diseases 0.000 description 3
- 238000011835 investigation Methods 0.000 description 3
- 239000013618 particulate matter Substances 0.000 description 3
- 230000000241 respiratory effect Effects 0.000 description 3
- 238000012216 screening Methods 0.000 description 3
- 239000000779 smoke Substances 0.000 description 3
- 238000009423 ventilation Methods 0.000 description 3
- XUCIJNAGGSZNQT-JHSLDZJXSA-N (R)-amygdalin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O[C@@H](C#N)C=2C=CC=CC=2)O1 XUCIJNAGGSZNQT-JHSLDZJXSA-N 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 2
- 206010038776 Retching Diseases 0.000 description 2
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 description 2
- BAECOWNUKCLBPZ-HIUWNOOHSA-N Triolein Natural products O([C@H](OCC(=O)CCCCCCC/C=C\CCCCCCCC)COC(=O)CCCCCCC/C=C\CCCCCCCC)C(=O)CCCCCCC/C=C\CCCCCCCC BAECOWNUKCLBPZ-HIUWNOOHSA-N 0.000 description 2
- PHYFQTYBJUILEZ-UHFFFAOYSA-N Trioleoylglycerol Natural products CCCCCCCCC=CCCCCCCCC(=O)OCC(OC(=O)CCCCCCCC=CCCCCCCCC)COC(=O)CCCCCCCC=CCCCCCCCC PHYFQTYBJUILEZ-UHFFFAOYSA-N 0.000 description 2
- 229940089837 amygdalin Drugs 0.000 description 2
- YZLOSXFCSIDECK-UHFFFAOYSA-N amygdalin Natural products OCC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC(C#N)c3ccccc3 YZLOSXFCSIDECK-UHFFFAOYSA-N 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 206010006451 bronchitis Diseases 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 208000017574 dry cough Diseases 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 230000007613 environmental effect Effects 0.000 description 2
- YGHHWSRCTPQFFC-UHFFFAOYSA-N eucalyptosin A Natural products OC1C(O)C(O)C(CO)OC1OC1C(OC(C#N)C=2C=CC=CC=2)OC(CO)C(O)C1O YGHHWSRCTPQFFC-UHFFFAOYSA-N 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- PHYFQTYBJUILEZ-IUPFWZBJSA-N triolein Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC(OC(=O)CCCCCCC\C=C/CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC PHYFQTYBJUILEZ-IUPFWZBJSA-N 0.000 description 2
- 238000003809 water extraction Methods 0.000 description 2
- 244000036905 Benincasa cerifera Species 0.000 description 1
- 235000011274 Benincasa cerifera Nutrition 0.000 description 1
- 206010006458 Bronchitis chronic Diseases 0.000 description 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 description 1
- 201000006306 Cor pulmonale Diseases 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 244000248825 Peltandra virginica Species 0.000 description 1
- 235000001188 Peltandra virginica Nutrition 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 235000008599 Poria cocos Nutrition 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 206010047924 Wheezing Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 208000007451 chronic bronchitis Diseases 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000002440 industrial waste Substances 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000005325 percolation Methods 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- -1 polypropylene Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229940126532 prescription medicine Drugs 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000009325 pulmonary function Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 229940117972 triolein Drugs 0.000 description 1
- 210000003135 vibrissae Anatomy 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines Containing Plant Substances (AREA)
- Non-Alcoholic Beverages (AREA)
Abstract
The invention provides a lung-clearing and lung-moistening plant beverage and a preparation method thereof, the lung-clearing and lung-moistening plant beverage is prepared from Chinese medicinal materials such as houttuynia cordata, rhizoma phragmitis, semen coicis, almond, peach kernel and platycodon grandiflorum, only six medicinal materials are selected in the formula, the formula dosage is reasonable, the structure is strict, the medicine properties are mild, and the lung-clearing and lung-moistening plant beverage has the effects of clearing heat, reducing phlegm, removing blood stasis, expelling pus, tonifying; the natural plant beverage is very suitable for being prepared into plant beverage, has original taste and flavor, pure taste and comfortable and palatable taste, does not contain any additive, can improve the autoimmune function of a human body after being drunk frequently, and has the effects of cleaning and nourishing the respiratory system of the human body.
Description
Technical Field
The invention belongs to the field of health-care food, and particularly relates to a lung-clearing and lung-moistening plant beverage and a preparation method thereof.
Background
Haze is a collective term for fog and haze, which is caused by the accumulation of a large number of artificially emitted pollutants under specific meteorological conditions. High concentrations of fine particulate matter (particulate matter having a particle size of 2.5 microns or less, abbreviated as PM2.5) or aerosol contamination are the root causes of haze.
The PM2.5 fine particles have small aerodynamic particle size and large specific surface area, are easy to carry a large amount of toxic and harmful substances such as industrial waste gas, volatile chemical substances, motor vehicle tail gas and the like, pass through the filtration effect of nose hair, enter the deep lung tissue of a human body through a respiratory tract and circulate blood, and cause serious harm to the health of the human body. Atmospheric particulates entering the respiratory tract damage the respiratory tract defense barrier by stimulating and corroding the alveolar wall, so that the pulmonary function is damaged, the incidence of pneumonia, chronic bronchitis, chronic obstructive pulmonary disease, bronchial asthma and the like is increased, and the respiratory system symptoms such as cough, expectoration, wheeze and the like appear in patients. Epidemiological statistics show that: with the increase of atmospheric particulate pollution concentration, the incidence of respiratory symptoms, pulmonary hypofunction, the morbidity and mortality of cardiopulmonary diseases are all obviously increased, and the two are directly related, and PM2.5 becomes an important influence factor of the continuous increase of the morbidity of a respiratory system.
In addition, many problems caused by smoking have become a problem of great social attention in recent years, and according to the investigation of the world health organization, one quarter of cancer patients account for 90% of smoking in industrially developed countries; dead from bronchitis, 75% of smoking; and most people are suffering from the harm of second-hand smoke, so that the method has great significance on reducing and lightening the harm to human beings caused by haze and improving the health of smokers.
Disclosure of Invention
In order to solve the problems, the invention provides a plant beverage for clearing lung and moistening lung, which is characterized by comprising the following components in parts by weight: is prepared from herba Houttuyniae 10-36 parts, rhizoma Phragmitis 6-18 parts, Coicis semen 6-18 parts, semen Armeniacae amarum 5-13 parts, semen Persicae 5-13 parts, and radix Platycodi 6-18 parts.
Specifically, the method comprises the following steps: the invention provides a lung-clearing and lung-moistening plant beverage which is characterized by comprising the following components in parts by weight: is prepared from houttuynia cordata 14-22 parts, reed rhizome 10-14 parts, coix seed 10-14 parts, almond 7-11 parts, peach kernel 7-11 parts and balloonflower root 10-14 parts.
According to the plant beverage for clearing smoke haze and moistening spleen and lung, one or more of white granulated sugar, cane sugar and a sweetener can be added according to the requirement of taste to prepare various beverages.
The invention also provides a preparation method of the plant beverage for clearing smoke haze and moistening spleen and lung, which comprises the following steps:
(1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root according to the formula ratio, putting the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root into an extraction tank, weighing the almond and the peach seed which are subjected to skin breaking according to the formula ratio, adding the almond and the peach seed into the extraction tank, uniformly mixing the medicinal materials, and adding hot water 15-20 times of the medicinal materials;
(2) controlling the extraction temperature at 90-100 deg.C, extracting at constant temperature for 30-120min, filtering the extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 3% -5% of the total amount of the beverage, dissolving the white granulated sugar in hot water, adding the dissolved white granulated sugar into the extract liquid obtained in the step (2), fixing the volume, filling nitrogen, filling and sterilizing to obtain the plant beverage.
Preferably, the houttuynia cordata, the reed rhizome, the coix seed and the platycodon grandiflorum in the step (1) are crushed to the granularity of 0.25-0.5mm, the almond and the peach kernel are crushed to the granularity of 0.5-0.8mm, and the hot water temperature is 80-90 ℃.
In the step (2), the extraction temperature is 95-100 ℃, and the extraction is carried out for 50-70min at constant temperature.
And (3) soaking the extracted precursor materials in the step (2) for 60-120 min.
And (3) sterilizing the hot water at 80-90 ℃, the filling temperature of 70-80 ℃ and 121 ℃ for 15-20 min.
Specifically, the preparation method of the plant beverage comprises the following steps:
(1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.35-0.45mm, putting into an extraction tank, weighing the peeled almond and the peach seed in the amount, crushing to the granularity of 0.6-0.7mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 15-20 times of hot water at 85-90 ℃;
(2) soaking at constant temperature for 60-90min, heating, controlling extraction temperature at 95-100 deg.C, extracting at constant temperature for 50-70min, filtering extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 4% of the total amount of the beverage, dissolving the white granulated sugar in hot water at 80-85 ℃, adding the extract liquid obtained in the step (2), fixing the volume, filling nitrogen, filling at 70-75 ℃, and sterilizing at 121 ℃ for 20min to obtain the plant beverage.
The principle and the beneficial effects of the invention are as follows:
firstly, in the course of carrying out pharmacodynamic study and technological study on the Sun Simiao classic famous prescription of Qianjin Phragmites communis, the pharmacodynamic effect is not significant enough and slow, so that primary and secondary medicaments are matched again, and houttuynia cordata, reed rhizome, coix seeds, almonds, peach kernels and platycodon grandiflorum are used as prescription medicaments through multiple prescription screening; in the formula, the houttuynia cordata is a monarch drug, has the effects of clearing away the lung-heat and detoxifying, not only clears away the lung-qi caused by haze and relieves the obstruction of the lung, but also dredges the descending of the lung to strengthen the lung power, so the usage amount is the largest; reed rhizome, sweet in nature, cold and light in nature, enters lung and stomach meridians, is good at clearing lung heat, promoting the production of body fluid and moistening lung, is moist and aversive to dryness, and can heal the lung moistening and dispersing; the coix seeds are sweet, bland and slightly cold, clear lung heat at the upper part and drain pus, and benefit intestines and stomach at the lower part and drain dampness, and the coix seeds are used as ministerial drugs for assisting monarch drugs in clearing heat and draining pus; the almond and the peach kernel can relieve cough and asthma, relax bowel, promote blood circulation and remove blood stasis, lead qi and blood to be smooth, and lead the zang organs to be flat, and the almond and the peach kernel can be used as adjuvant drugs together with monarch drugs; the platycodon root is pungent and bitter in taste, enters lung and stomach channels, relieves sore throat, eliminates phlegm, disperses the lung and expels pus, can disperse and disperse, carries various medicines to float upwards, and is guided to the lung as a guiding drug. In a word, the six medicines in the formula, monarch, minister, assistant and guide, have strict structure and mild medicine property, and have the effects of clearing heat and removing toxicity, ventilating lung and expelling pus. The efficacy of the traditional Chinese medicine is obviously superior to that of the Qianjin Reed stem decoction and other prescription medicines added or subtracted according to clinical evidence, the prescription and the medicine adopt food and material dual-purpose medicinal materials, the nature of the medicine is taken, the taste of food is used, the medicine and food power are combined, the medicine and food are integrated, the effects of both the medicine and the food are fully exerted, the traditional Chinese medicine is very suitable for being prepared into plant beverages, the plant beverage has original taste and flavor, no additive is contained, the taste is pure, the taste is comfortable and palatable, and the plant beverage does not deteriorate after being stored for a. The product can improve immunity and has effects of cleaning and nourishing respiratory system.
Secondly, the constant temperature extraction temperature is controlled to be 90-100 ℃, the extract can better enrich drug effect components such as houttuynine sodium bisulfite, glycerol trioleate and the like, has obvious effects of clearing heat and detoxicating, ventilating and discharging pus, and keeps the high temperature of more than 70 ℃ for operation in the whole process of extraction, constant volume and filling, thereby avoiding the infection of introducing foreign bacteria and ensuring the safety of products.
In order to better illustrate the advantageous effects of the present invention, the following test examples are also presented in the present invention, which are intended to illustrate the advantageous effects of the present invention, but are by no means limited to the scope of protection of the present invention.
First, pharmacodynamic study
Experimental example 1 study on protective action of respiratory system injury of rat caused by fine particulate air
Experimental methods
1.1 test animals
SD rats, SPF grade. The number of the animals is 90, the animals are half female and half male, the animals are 6-8 weeks old when the animals are ordered, and the weight of the animals is 180-200 g.
1.2 Standard and groups for laboratory animal feeding
The experimental animal facility continuously maintained the barrier environmental standards. Control range of main environmental index: the room temperature is 20-26 ℃, and the daily temperature difference is less than or equal to 4 ℃. The relative humidity is 40-70%. Minimum ventilation times 15/hr, light illumination: dark-12 h: and (4) 12 h. Animals were housed in polypropylene rat herding boxes, with the cage specifications: 545 395 200mm3, 3-5 boxes, and the feeding space of the box meets the requirement of national standard GB14925-2010 of the people's republic of China on the minimum space required by experimental animals. All animals were kept by trained qualified personnel. Change bedding and cages 1 time per week. The special feed for the rats is added for the animals to eat every day, and the drinking water bottles are used for filling water for the animals to drink, so that the free diet activity of the animals is kept in the whole feeding process. And (5) quarantining the newly-received animals for 5-7 days, and determining that the animals are healthy and disease-free, so that the animals can be used.
Grouping according to animal weight by a layering and randomization grouping method; the male and female animals are grouped respectively:
control group (control): 10 rats, exposed to clean inhalation contamination device for inhaling clean air for 30min daily; model group (model): exposing 10 rats to an air fine particle aerosol toxicant exposure device every day in the mouth and nose, and inhaling air haze for 30 min; test groups 1 to 7: 10 rats, male and female halves. Exposing the mouth and nose parts to an air fine particle aerosol toxicant exposure device every day, and inhaling air haze for 30 min; 1 hour before infection, the stomach is drenched and given with 1ml/100g of liquid medicine, and the administration conditions of the test groups are as follows:
test group 1: the Qianjin phragmites decoction (the formula comprises 60g of phragmites, 30g of melon petals, 9g of coix seeds and 24g of peach kernels);
test group 2: 30g of heartleaf houttuynia herb, 45g of reed rhizome, 8g of platycodon grandiflorum, 7g of almond, 20g of coix seed and 9g of peach kernel are added into the decoction;
test group 3: 12g of heartleaf houttuynia herb, 12g of reed rhizome, 8g of platycodon grandiflorum, 8g of coix seed and 9g of peach seed;
test group 4: 30g of heartleaf houttuynia herb, 30g of reed rhizome, 8g of almond, 9g of coix seed and 9g of peach seed;
test group 5: 60g of reed rhizome, 8g of platycodon grandiflorum, 8g of almond, 9g of coix seed and 9g of peach seed;
experimental group 6: shengyuan Shujin carousing houttuynia and almond solid beverage (prescription is houttuynia, coix seed, Chinese waxgourd seed, malt, almond, peach kernel, tuckahoe; produced by Guangzhou one side pharmaceutical Co., Ltd.)
The anti-haze effect of the traditional Chinese medicine plant beverage is investigated and evaluated from the aspects of weight, lung function and the like by continuously inhaling fine air particles (establishing a haze environment through HOPE-MED dust mouth-nose type contamination equipment) into SD rats for 8 weeks, and performing drug intervention by intragastrically administering a drug solution while contamination.
Results of the experiment
1. Evaluation of growth characteristics of rats:
by inhaling fine air particles into SD rats for 8 weeks continuously (establishing a haze environment through HOPE-MED dust type mouth-nose-operated toxicant exposure equipment), gavage the stomach while carrying out drug intervention, observing for 1 time per day, observing the living condition of animals after each toxicant exposure, and measuring the weight of mice after 8 weeks of continuous toxicant exposure, the results are as follows in the following table 1:
table 1: SD rat weight measurement of inhaled air fine particles for 8 continuous weeks
| Group of | Body weight (g) before experiment | Body weight (g) after 8 weeks of exposure to toxicity | Weight gain (g) |
| Control group | 189.5±8.3 | 220.5±9.1 | 31.0±2.1 |
| Model set | 190.6±8.1 | 200.7±10.1 | 10.1±1.8 |
| Test group 1 | 188.3±8.3 | 204.3±13.3 | 16.0±1.9 |
| Test group 2 | 191.4±7.5 | 218.6±12.5 | 27.4±2.5 |
| Test group 3 | 189.7±8.7 | 206.1±13.7 | 16.4±2.2 |
| Test group 4 | 190.5±7.9 | 205.2±11.9 | 15.1±1.7 |
| Test group 5 | 189.2±8.3 | 207.1±12.3 | 17.9±2.3 |
| Test group 6 | 190.4±8.2 | 206.5±11.3 | 16.1±1.3 |
Test results table: the body weight of each group of infected animals increased more slowly than that of the control group. The test groups 1-6 can effectively improve the influence of the SD rat on the growth and development of animals after continuously inhaling the fine particulate matters for 8 weeks, wherein the test group 2 adopts the formula determined by the invention for administration, the effect is most obvious, the growth and development conditions of the SD rat after continuously inhaling the fine particulate matters for 8 weeks are close to those of a normal control group, and the influence of the drug group determined by the invention on the living conditions of the SD rat in a haze environment can be obviously improved.
2. Evaluation of rat respiratory function:
the lung function of a conscious rat is measured by adopting an EMKA animal lung function monitoring system, the EMKA animal lung function monitoring system is placed in a quiet laboratory, the system is corrected, calibrated and ventilated before formal measurement, the data acquisition frequency is automatically acquired once every 5 seconds, and the measurement result is displayed once every minute. The rats are placed in a whole body scanning meter box to adapt for 5-10min, the recording time is 3-8min, and the average value of the results of each animal is taken as the measurement result of the lung function of the animal. The measured indices include inspiration time (Ti), expiration time (Te), Tidal Volume (TV), Expiration Volume (EV), Relaxation Time (RT), and Minute Ventilation (MV).
The respiratory function of the animals was measured every 2 weeks during the exposure period of the rats, and the rats were placed in a whole plethysmograph box and connected to a respiratory function measuring instrument for measurement, and the results are shown in Table 2.
Table 2: continuous inhalation of infected SD rat respiratory function determination:
and (3) analyzing test results:
the Ti value of the inhaled toxicant of the model group rats is obviously higher than that of the control group (p <0.05), and the RT value of the toxicant SD rats is obviously higher than that of the control group (p <0.05), which indicates that when the lung function indexes related to the flow and the volume of the model group rats are obviously inhibited, the animals can maintain the relatively required lung function by prolonging the expiration time and the relaxation time. The rats TV, EV and MV in the model group all decreased to different degrees during the observation period, indicating that the volume of breath was significantly decreased and the lung ventilation function reserve was also decreased. Compared with the model group, the experimental group 1-6 can obviously improve and improve the lung function damage of the rat caused by continuous fine particulate matter inhalation, and has certain improvement effect. And the administration intervention of the prescription determined by the invention in the test group 2 is adopted, the effect of improving the respiratory function of the continuous inhalation contaminated SD rat is most obvious, the respiratory function of the continuous inhalation contaminated SD rat is improved to be close to that of a normal control group and is obviously superior to that of other test groups, so that the traditional Chinese medicine formula determined by the invention has outstanding pharmacodynamic activity and can obviously improve the damage of haze to the respiratory system.
Test example 2: curative effect investigation of lung-clearing and lung-moistening plant beverage prepared by the invention
Subject: 180 patients with symptoms of pharyngeal discomfort and dry cough frequently work outdoors in the period of high haze in winter in Beijing.
The experimental method comprises the following steps: dividing the experimental subject into test groups 1-5 and control groups, each group containing 30 persons;
test groups A1-A6: the plant beverage for clearing lung and moistening lung prepared in the embodiments 1-6 of the invention is sequentially assigned to the experimental subjects of group A1-A5 for administration, and the administration method comprises the following steps: 1 bottle (310ml) each time, 2 times daily, and continuously taking for 7 days;
normal control group: only drinking water is taken.
The results are shown in Table 3.
Table 3: the invention relates to a therapeutic effect investigation condition table of a lung-clearing and lung-moistening plant beverage
The test result shows that after 7 days, only 4 persons, 6 persons and 20 persons with relief are shown in the normal control group, and after 7 days, the number of persons with obvious improvement of symptoms reaches 16-23 persons in the test group A2-A5 (the plant beverage prepared by the invention); the number of people who relieved is 7-12, and 0 who has no obvious effect, and the test group A3 has the best effect, and the number of people who have obvious improvement of symptoms is as many as 23; the number of people relieved is 7, and the number of people without obvious effect is 0, so that the plant beverage has obvious curative effects on symptoms such as pharyngeal discomfort, dry cough and the like. And preferably 10-36 parts of houttuynia cordata, 6-18 parts of reed rhizome, 6-18 parts of platycodon grandiflorum, 5-13g parts of almond, 6-18 parts of coix seed and 5-13 parts of peach seed, and the formula has the best curative effect and is more reasonable.
Test example 3: the lung-clearing and lung-moistening plant beverage prepared by the invention is used for improving respiratory discomfort caused by smoking:
test subjects: more than 3 years of smoking, there are 120 smokers with symptoms of pharyngeal discomfort, retching, excessive phlegm and the like.
The experimental method comprises the following steps: dividing the experimental subject into test groups 1-3 and a control group, wherein each group contains 20 persons;
test group 1: the ancient formula of Qianjin Phragmites communis stem decoction is taken every day;
test group 2: the heartleaf houttuynia herb and almond solid beverage (produced by Guangzhou one-party pharmaceutical Co., Ltd.) is sold on the market;
test group 3: the lung-clearing and lung-moistening plant beverage prepared by the invention;
the taking method comprises the following steps: the preparation is administered 2 times per day at a dose of 310ml for 7 days;
normal control group: only drinking water is taken.
The results are shown in Table 4.
Table 4: the lung-clearing and lung-moistening plant beverage prepared by the invention is used for improving respiratory discomfort caused by smoking:
the test result shows that: in the normal control group, after 7 days, only 5 persons with obvious improvement, 5 persons with relief and 20 persons without obvious improvement are shown; the lung-clearing and lung-moistening plant beverage prepared by the invention only shows 22 persons who obviously improve, 7 persons who relieve the lung-clearing and lung-moistening plant beverage, and only 1 person who does not obviously improve the lung-clearing and lung-moistening plant beverage; and is obviously superior to the test group 1 and the test group 2, thereby showing that the lung-clearing and lung-moistening beverage has obvious curative effects on symptoms such as respiratory tract pharyngeal discomfort, retching, excessive phlegm and the like caused by smoking.
Second, the study of the technology
1. Screening an extraction mode: in the process of technological research, in order to utilize the active ingredients of each medicament to the maximum extent, modes such as water decoction extraction, ethanol reflux extraction, ethanol percolation extraction and the like are respectively investigated, and the results show that the high-temperature water extraction mode is adopted, so that the extraction efficiency of the active ingredients of the medicinal materials in the formula is high, the contents of houttuynin, amygdalin and the like are high, the dissolved substances are more, the water decoction mode is more suitable for the production of beverages, the influence of non-drinking solvents on the safety of the products is avoided, and the method is more economic. The factors such as production time, production cost and the like in the large-scale production are integrated, and the extraction temperature and the extraction time are further investigated.
The results of the examination by adopting 5 temperature gradients (70-80 ℃, 80-90 ℃, 90-95 ℃, 95-100 ℃ and 90-100 ℃) and 4 extraction time periods (30-60min, 60-120min, 90-180min and 30-120min) show that when the extraction is carried out at the constant temperature of 90-100 ℃ for 30-120min, the extract can enrich the active ingredients of the medicine, and the detection shows that the crude drug with the houttuynine sodium bisulfite content of more than or equal to 0.04 percent, the crude drug with the triolein content of more than or equal to 0.65 percent, the crude drug with the amygdalin content of more than or equal to 7.2 percent and the crude drug with the total extract of more than or equal to 50 percent can exert the maximum efficacy. Wherein, the effect is best when the temperature is kept for soaking for 60-120min and the constant temperature is 95-100 ℃ before extraction, the content of active ingredients is ideal, and the extraction time can be shortened to 50-70 min. Due to the dual functions of soaking in advance and high-temperature extraction, the extraction time is effectively shortened, and the method is very beneficial to mass production.
2. Subsequent process study: in the research process, the temperature in the process is continuously kept to be 70-90 ℃ in the subsequent auxiliary material adding, constant volume and filling stages, so that the inconvenience of prolonging the process time, increasing the production cost and the like caused by temperature rise in subsequent high-temperature sterilization is avoided, and more importantly, the operation of continuously keeping higher temperature in the whole production link can avoid introducing infection of foreign bacteria, so that the safety of the product is ensured.
3. Raw material crushing granularity screening: the crushing or crushing degree of raw medicinal materials has great influence on the dissolution of active ingredients during extraction, the study finds that the almond and the peach kernel contain oily ingredients, the dissolution of the active ingredients is not facilitated due to overlarge crushing particle size, the adhesion and influence of the almond and the peach kernel on medicinal materials such as reed rhizome, platycodon root and the like and the self are increased in the water extraction process due to partial exudation of the oily substances caused by crushing due to over fine crushing, and the crushing degree of the medicinal materials such as houttuynia cordata and the like also considers the crushing particle size of the almond and the like to balance the two so as to facilitate the extraction.
In conclusion, the preparation process obtained by optimization is very simple and easy to operate, and can save the production cost and improve the production efficiency. And the plant extraction efficiency is high, the active ingredients of the medicine can be enriched, and the maximum medicine effect can be exerted.
The specific implementation mode is as follows:
example 1: lung-clearing and lung-moistening plant beverage (Low component)
The formula is as follows: 8g of heartleaf houttuynia herb, 4g of reed rhizome, 5g of coix seed, 4g of almond, 4g of peach seed and 5g of platycodon root
The preparation method comprises the following steps: (1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.25mm, putting into an extraction tank, weighing the peeled almond and the peach seed, crushing to the granularity of 0.5mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 15 times of hot water at 90 ℃;
(2) soaking at constant temperature for 60min, heating, controlling extraction temperature at 90 deg.C, extracting at constant temperature for 80min, filtering extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 3% of the total amount of the beverage, dissolving the white granulated sugar in hot water at 80 ℃, adding the extract liquid obtained in the step (2), fixing the volume to 2000ml, filling nitrogen, filling at 70 ℃, and sterilizing at 121 ℃ for 18min to obtain the plant beverage.
Example 2: lung clearing and moistening plant beverage
The formula is as follows: 10g of heartleaf houttuynia herb, 6g of reed rhizome, 6g of coix seed, 5g of almond, 5g of peach seed and 6g of platycodon root
The preparation method comprises the following steps: (1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.5mm, putting into an extraction tank, weighing the peeled almond and the peach seed, crushing to the granularity of 0.8mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 20 times of hot water at 80 ℃;
(2) soaking at constant temperature for 120min, heating, controlling extraction temperature at 100 deg.C, extracting at constant temperature for 30min, filtering extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 5% of the total amount of the beverage, dissolving the white granulated sugar in hot water at 90 ℃, adding the extract liquor obtained in the step (2), fixing the volume to 2000ml, filling nitrogen, filling at 80 ℃, and sterilizing at 121 ℃ for 15min to obtain the plant beverage.
Example 3: lung clearing and moistening plant beverage
The formula is as follows: 14g of heartleaf houttuynia herb, 10g of reed rhizome, 10g of coix seed, 7g of almond, 7g of peach seed and 10g of platycodon root
The preparation method comprises the following steps: (1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.35mm, putting into an extraction tank, weighing the peeled almond and the peach seed, crushing to the granularity of 0.6mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 18 times of hot water at 85 ℃;
(2) soaking at constant temperature for 90min, heating, controlling extraction temperature at 100 deg.C, extracting at constant temperature for 50min, filtering extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 5% of the total amount of the beverage, dissolving the white granulated sugar in hot water at 90 ℃, adding the extract liquor obtained in the step (2), fixing the volume to 2000ml, filling nitrogen, filling at 75 ℃, and sterilizing at 121 ℃ for 20min to obtain the plant beverage.
Example 4: lung clearing and moistening plant beverage
The formula is as follows: 22g of heartleaf houttuynia herb, 14g of reed rhizome, 14g of coix seed, 11g of almond, 11g of peach seed and 12g of platycodon root
The preparation method comprises the following steps: (1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.45mm, putting into an extraction tank, weighing the peeled almond and the peach seed, crushing to the granularity of 0.7mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 16 times of hot water at 85 ℃;
(2) soaking at constant temperature for 100min, heating, controlling the extraction temperature at 95 deg.C, extracting at constant temperature for 70min, filtering the extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 4% of the total amount of the beverage, dissolving the white granulated sugar in hot water at 85 ℃, adding the extract liquor obtained in the step (2), fixing the volume to 2000ml, filling nitrogen, filling at 75 ℃, and sterilizing at 121 ℃ for 18min to obtain the plant beverage.
Example 5: lung clearing and moistening plant beverage
The formula is as follows: 36g of houttuynia cordata, 18g of rhizoma phragmitis, 18g of coix seed, 13g of almond, 11g of peach seed and 18g of platycodon grandiflorum
The preparation method comprises the following steps: (1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.45mm, putting into an extraction tank, weighing the peeled almond and the peach seed, crushing to the granularity of 0.7mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 20 times of hot water at 95 ℃;
(2) soaking at constant temperature for 80min, heating, controlling extraction temperature at 100 deg.C, extracting at constant temperature for 120min, filtering extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 3% of the total amount of the beverage, dissolving the white granulated sugar in hot water at 90 ℃, adding the extract liquor obtained in the step (2), fixing the volume to 2000ml, filling nitrogen, filling at 80 ℃, and sterilizing at 121 ℃ for 20min to obtain the plant beverage.
Example 6: lung-clearing and lung-moistening plant beverage (high component)
The formula is as follows: 38g of heartleaf houttuynia herb, 20g of reed rhizome, 20g of coix seed, 14g of almond, 14g of peach seed and 20g of platycodon root
The preparation method comprises the following steps: (1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.5mm, putting into an extraction tank, weighing the peeled almond and the peach seed, crushing to the granularity of 0.8mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 20 times of hot water at 95 ℃;
(2) soaking at constant temperature for 90min, heating, controlling the extraction temperature at 100 deg.C, extracting at constant temperature for 90min, filtering the extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 5% of the total amount of the beverage, dissolving the white granulated sugar in hot water at 95 ℃, adding the extract liquor obtained in the step (2), fixing the volume to 2000ml, filling nitrogen, filling at 80 ℃, and sterilizing at 121 ℃ for 20min to obtain the plant beverage.
Claims (5)
1. A plant beverage for clearing lung and moistening lung is characterized in that: the traditional Chinese medicine composition is prepared from 14-22 parts by weight of houttuynia cordata, 10-14 parts by weight of reed rhizome, 10-14 parts by weight of coix seed, 7-11 parts by weight of almond, 7-11 parts by weight of peach seed and 10-14 parts by weight of platycodon grandiflorum according to the following method:
(1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root according to the formula ratio, putting the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root into an extraction tank, weighing the almond and the peach seed which are subjected to skin breaking according to the formula ratio, adding the almond and the peach seed into the extraction tank, uniformly mixing the medicinal materials, and adding hot water 15-20 times of the medicinal materials;
(2) controlling the extraction temperature at 90-100 deg.C, extracting at constant temperature for 30-120min, filtering the extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 3% -5% of the total amount of the beverage, dissolving in hot water, adding into the extract liquid obtained in the step (2), fixing the volume, filling nitrogen, filling and sterilizing to obtain the plant beverage;
pulverizing herba Houttuyniae, rhizoma Phragmitis, Coicis semen, and radix Platycodi in step (1) to particle size of 0.25-0.5mm, pulverizing semen Armeniacae amarum and semen Persicae to particle size of 0.5-0.8mm, and heating with hot water at 80-90 deg.C;
the hot water in the step (3) is heated to 80-90 ℃, the filling temperature is 70-80 ℃, and the sterilization is carried out for 15-20min at 121 ℃;
the lung clearing and moistening effects are as follows: protecting respiratory system damage caused by fine air particles, and improving respiratory tract discomfort caused by smoking.
2. The plant beverage for clearing lung and moistening lung as claimed in claim 1, wherein: can be added with one or two of white granulated sugar and sucrose to make into beverage with different tastes.
3. The plant beverage for clearing lung and moistening lung as claimed in claim 1, wherein: in the step (2), the extraction temperature is 95-100 ℃, and the extraction is carried out for 50-70min at constant temperature.
4. The plant beverage for clearing lung and moistening lung as claimed in claim 1, wherein: and (3) soaking the extracted precursor materials in the step (2) for 60-120 min.
5. The preparation method of the plant beverage for clearing lung and moistening lung according to claim 1, characterized by comprising the following steps: the method comprises the following steps:
(1) weighing the heartleaf houttuynia herb, the reed rhizome, the coix seed and the platycodon root, crushing to the granularity of 0.35-0.45mm, putting into an extraction tank, weighing the peeled almond and the peach seed in the amount, crushing to the granularity of 0.6-0.7mm, adding into the extraction tank, uniformly mixing the medicinal materials, and adding 15-20 times of hot water at 85-90 ℃;
(2) soaking at constant temperature for 60-90min, heating, controlling extraction temperature at 95-100 deg.C, extracting at constant temperature for 50-70min, filtering extractive solution, and collecting;
(3) weighing white granulated sugar accounting for 4% of the total amount of the beverage, dissolving in hot water at 80-85 deg.C, adding the extractive solution of step (2), fixing volume, charging nitrogen, bottling at 70-75 deg.C, and sterilizing at 121 deg.C for 20min to obtain the plant beverage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710123251.2A CN106692790B (en) | 2017-03-03 | 2017-03-03 | Plant beverage capable of moistening lung and clearing lung and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710123251.2A CN106692790B (en) | 2017-03-03 | 2017-03-03 | Plant beverage capable of moistening lung and clearing lung and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106692790A CN106692790A (en) | 2017-05-24 |
| CN106692790B true CN106692790B (en) | 2020-09-01 |
Family
ID=58917394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710123251.2A Active CN106692790B (en) | 2017-03-03 | 2017-03-03 | Plant beverage capable of moistening lung and clearing lung and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106692790B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107296191A (en) * | 2017-07-12 | 2017-10-27 | 润己饮料（河源）有限公司 | The formula and its manufacture craft of a kind of cordate houttuynia plant beverage |
| CN107455627A (en) * | 2017-07-31 | 2017-12-12 | 贵州盛达生植物发展有限公司 | A kind of dendrobium candidum plant beverage and preparation method thereof |
| CN107568554A (en) * | 2017-09-30 | 2018-01-12 | 朱昱光 | A kind of solid beverage |
| CN108721425B (en) * | 2018-06-12 | 2021-06-04 | 天津市中科众晟医疗科技有限责任公司 | Lung-clearing acupoint application paste and preparation method thereof |
| CN113499400A (en) * | 2021-06-18 | 2021-10-15 | 建昌帮药业有限公司 | Traditional Chinese medicine composition and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101077114A (en) * | 2007-06-27 | 2007-11-28 | 修正药业集团股份有限公司 | Lung-clearing tea and preparation method thereof |
| CN103263059A (en) * | 2013-05-23 | 2013-08-28 | 珠海圣原生物科技有限公司 | Solid beverage for clearing away lung-heat, promoting diuresis, reducing phlegm and relieving cough and preparation method thereof |
| CN106806730A (en) * | 2015-12-02 | 2017-06-09 | 吴昊 | A kind of medicine for treating pulmonary cyst |
-
2017
- 2017-03-03 CN CN201710123251.2A patent/CN106692790B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101077114A (en) * | 2007-06-27 | 2007-11-28 | 修正药业集团股份有限公司 | Lung-clearing tea and preparation method thereof |
| CN103263059A (en) * | 2013-05-23 | 2013-08-28 | 珠海圣原生物科技有限公司 | Solid beverage for clearing away lung-heat, promoting diuresis, reducing phlegm and relieving cough and preparation method thereof |
| CN106806730A (en) * | 2015-12-02 | 2017-06-09 | 吴昊 | A kind of medicine for treating pulmonary cyst |
Non-Patent Citations (1)
| Title |
|---|
| 肺痈变证;熊继柏;《福建中医药》;19870131(第01期);第45和46页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106692790A (en) | 2017-05-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106692790B (en) | Plant beverage capable of moistening lung and clearing lung and preparation method thereof | |
| CN102940832B (en) | Medicament for treating chronic bronchitis and preparation method thereof | |
| CN106138360A (en) | A kind of Chinese medicine composition and preparation method thereof, application | |
| CN112022957A (en) | Traditional Chinese medicine lung moistening, toxin expelling and lung clearing tea | |
| CN103719491B (en) | A kind of sealwort invigorating the spleen moistening lung health protection tea and preparation method thereof | |
| CN105326888A (en) | Medicinal composition for treating child phlegm-heat obstructing lung type asthma | |
| CN111467459B (en) | Traditional Chinese medicine composition for treating novel coronavirus pneumonia at recovery stage, application and preparation method thereof | |
| CN107625828A (en) | A kind of health protection tea for auxiliary treatment chronic pharyngitis, preparation method and application | |
| CN106511740A (en) | Radix ginseng-containing health product and preparation method therefor | |
| CN105194341B (en) | The drug for treating xerostomia after head and neck neoplasm radiotherapy | |
| CN105832848A (en) | Traditional Chinese medicine composition for poultry respiratory diseases and preparation method thereof | |
| CN1175885C (en) | Zibei Cough stopping granules and its preparation method | |
| CN104840737B (en) | Chinese medicine composition with qi invigorating and lung moistening effect and its preparation method and application | |
| CN107158286B (en) | Traditional Chinese medicine composition for treating respiratory tract injury induced symptoms caused by haze and preparation method thereof | |
| CN105497513A (en) | Traditional Chinese medicine preparation for treating chronic pharyngitis | |
| CN114681583B (en) | Throat-clearing lung-benefiting smoking-stopping composition, and preparation method and application thereof | |
| CN109663012A (en) | Dispelling wind and heat, removing toxic substances relieving sore-throat Chinese medicine composition and the preparation method and application thereof | |
| CN114470110B (en) | Anti-rhinitis traditional Chinese medicine composition with pain relieving effect | |
| CN108498688A (en) | A kind of Chinese medicine soft extracts and preparation method thereof with cough-relieving function | |
| CN116211993B (en) | Composition for treating senile chronic disease and its preparation method | |
| CN103735884B (en) | A kind of medicine treating cough and preparation thereof | |
| CN111569029B (en) | Traditional Chinese medicine composition for improving respiratory tract mucosa immunologic function and preparation method thereof | |
| CN109106842B (en) | A medicine for stopping smoking and its preparation method | |
| CN1634340A (en) | Medicinal composition for preventing and treating children respiratory system diseases and preparation method thereof | |
| CN118021929A (en) | Pharmaceutical composition for treating cough and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: No.1 Changqing Road, Shangba Industrial Park, Daozhen Autonomous County, Zunyi City, Guizhou Province Applicant after: GUIZHOU EVERGREEN PHARMACEUTICAL Co.,Ltd. Address before: 563500 Guizhou city in Zunyi Province, Daozhen yilao and Miao Autonomous County Xintian Village Center BA Xiang Group Applicant before: GUIZHOU EVERGREEN PHARMACEUTICAL Co.,Ltd. |
|
| CB02 | Change of applicant information | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |