CN106668703A - Hui nationality traditional Chinese medicinal Rhizoma Curcumae and Araiia chinensis L. root bark esophagus cancer treatment granule and preparation method thereof - Google Patents

Hui nationality traditional Chinese medicinal Rhizoma Curcumae and Araiia chinensis L. root bark esophagus cancer treatment granule and preparation method thereof Download PDF

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CN106668703A
CN106668703A CN201510749266.0A CN201510749266A CN106668703A CN 106668703 A CN106668703 A CN 106668703A CN 201510749266 A CN201510749266 A CN 201510749266A CN 106668703 A CN106668703 A CN 106668703A
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cancer
granule
extract
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medicine
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王学礼
王桂珍
马芳
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Yinchuan Shanghetu New Technology Development Co Ltd
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Yinchuan Shanghetu New Technology Development Co Ltd
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Abstract

The invention concretely relates to a formula and a preparation method of a Hui Nationality traditional Chinese medicinal Rhizoma Curcumae and Araiia chinensis L. root bark esophagus cancer treatment granule. The granule is a green high-tech Chinese herbal medicine used for treating the esophagus cancer. The granule is a traditional Chinese medicinal granule prepared through the following steps: mixing of Rhizoma Curcumae, Araiia chinensis L. root bark, Smilax scobinicaulis C.H. Wright, Salvia miltiorrhiza and other Chinese herbal medicines according to a certain ratio, water adding, decoction, extraction, concentration and granulation. The granule is mainly used for treating the esophagus cancer, and also is used for treating throat cancer, stomach cancer, colorectal cancer and other digestive system cancers. The granule has the characteristics of suitable medicine variety quantity and moderate dosage, and all the medicines are proved by modern medical science pharmacological experiments to be suitable for treating the cancers. The granule fundamentally improves the body functions and prevents and treats cancer cancerization at a low cost in order to recover the health of bodies.

Description

Hui ethnic group's Chinese medicine art wood oesophagus holds back cancer particle and preparation method thereof
Technical field
It is a kind of green high-tech of the prevention and treatment cancer of the esophagus that Hui ethnic group's Chinese medicine art wood oesophagus according to the present invention holds back cancer particle Skill Chinese herbal medicine.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, China The probability that people suffers from malignant tumour in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumour, tumour China into For a kind of common disease.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase. And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patient with esophageal carcinoma Account for the 29.7% of Alimentary System patient, almost half.
Cancer of the esophagusDisease locus typically organize in epithelium of esophagus, its directly impact be exactly that patient swallows and digest work( Can, health is slowly etched with regard to this.The pathogenic factor of cancer of the esophagus mainly has three, and one is malnutritive, though i.e. people now Living standard improve, but due to the change of diet hobby and mode, will also result in malnutritive and trace element lacking It is weary;Two is that diet is lack of standardization, and in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase, These materials are easily-synthesized carcinogen nitrosamine in stomach;Three be esophageal injury and disease induction, esophageal injury and some food Pipe disease is likely to become the inducement for causing cancer of the esophagus, is detained and cause long-term chronic inflammation, ulcer because of in oesophagus, or slowly Sexual stimulus, and then esophageal epithelial proliferation, finally result in canceration.Although cancer of the esophagus does not possess infectiousness, the destruction to human body But it is not allow to look down upon.
Though the early symptom of the cancer of the esophagus is more substantially, usual to be always mistakenly considered flu etc by people, therefore is often neglected Depending on, but do not know that the speed that cancer of the esophagus slowly deteriorates is very fast, once and feel increasingly apparent to be difficult to swallow, most likely Deteriorate as cancer.Afterwards may be by operation to the process of cancerization Regional resection, to reduce the death rate of cancer of the esophagus.
At present treatment cancer of the esophagus the best way is operation, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, suffer from Person's pain is difficult to stand, and success rate is also very low, and the life cycle after most Chemotherapy in Patients was with regard to 1 year or so --- certainly This is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some perform the operation, due to a variety of causes Hold and can't stand chemotherapy, can only palliative treatment, expect that miracle comes ...
The cancer of the esophagus is at present more refractory disease more as cancer of the stomach, all, but refractory representative cannot be controlled, except above-mentioned doctor trained in Western medicine Outside treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science is with organic conception according to the dialectical opinion of whole body feature of patient Control, go for various each phase cancer.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is light Micro-, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense Than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, Improve cancer related symptoms, improve life quality, extend life cycle.But the problem for existing is that the prescription uniformity of the traditional Chinese medical science is poor, Treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always have in selected Chinese herbal medicine medicinal material --- it is most It is more than more than half --- medicine is all not proved function for cancer and acted on by modern medicine pharmacological evaluation " to distinguish Card treat " " compatibility " medicine, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often delay control The time of disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatability Poor, high level evidence-based medicine EBM is theoretical and evidence is relative lacks, thus the situation for mainly waiting deficiency by rule of thumb for cancer, proposition one The new dosage of kind and preparation method, there is provided one kind reduces the incidence of disease of the cancer of the esophagus from the beginning of prevention, starts to subtract from canceration Delay its tempo, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one is special Shi Yongyu esophageal ulcer before cancer not treated in case its canceration, two is can to treat cancer just ulcer, in case it continues to deteriorate, three It is inducible into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improves physical function, so as to recover strong Health.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In tool In the formula of body, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, induced because of esophageal injury, disease according to the origin cause of formation of cancer of the esophagus, dietary preferences nutrition is lost Weighing apparatus causes immunologic hypofunction, causes normal cell to be compromised because of Helicobacter pylori infection, apoptosis, and digestive tract ulcer, canceration " are taken advantage of It is empty and enter ", because " weakened body resistance poison is poly- ", " void in healthy tendency " and the characteristics of cause the basic pathology interpretation of the cause, onset and process of an illness such as metastases, with or righting dispel Heresy, orTonification and purgation in combination, or regulating qi to disperse stagnation, or solve strongly fragrant resolving sputum, or clearing heat and detoxicating, or reinforcing and reducing methods and the method used, with correct void in healthy tendency, Poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjusts and improves the immunologic function of body, to reach overall tumor suppression Purpose, so as to improve the overall curative effect and late result of carninomatosis treatment, provides for esophageal cancer patients and a kind of is cured by modern Learn green high-tech Chinese herbal medicine formula and compound method that pharmacological evaluation proves function for cancer and effect, with very low or Relatively low cost, fundamentally improves physical function, and the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and the final body that recovers is good for Health.Thus also to patient one according to the personal state of an illness, economic situation, personal inclination come consider select different treatment methods or Several method shares particularly traditional Chinese and western medicine and combines the leeway of complex treatment application, to obtaining optimum curative effect, easily improves life Deposit rate --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
Hui ethnic group's Chinese medicine art wood oesophagus of the first, the described prevention and treatment cancer of the esophagus holds back cancer particle and preparation method thereof, is by following Made by weight proportion raw material:
Curcuma zedoary 30g, neglect wood 30g, iron pierce Siberian cocklebur 30g, Fourstamen Stephania Root 9g,
Pellet feed 13g, dark plum 7g, Chinese lobelia 25g, arillus longan 15g,
Pseudo-ginseng 7g, camplotheca acuminata 7g, walnut kernel 15g, Radix Glycyrrhizae 9g
This side is substantially square for one decoction on the one.In practical application, can also be increased according to the physique of patient and conditions Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must apply special process It is prepared.
2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal granule of the present invention:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to walnut kernel 15g, Radix Glycyrrhizae 9g, all amplify 10 times, clear water is clear After washing, it is placed in BT-2 stainless steels and extracts in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, point From extract, pressure filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract half an hour Left and right, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes Left and right, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), 80 DEG C are heated to, relative density 1.10~1.20 is concentrated into, it is standby.
(3), powder processed
Walnut kernel 15g, Radix Glycyrrhizae 9g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stirring is equal It is even.
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated.
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed.
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.
B, packaging
First the pill for making is fitted into vinyon pouch, every bag of 8-9g, then by the pouch mounted box for installing, vanning, sterilizing (60Co irradiation is adopted, irradiation dose is 8kGy).
, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Three times a day, 1 bag of 8-9g every time, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid Water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.
This medicine does medicine efficacy enhancing ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is:Take from so ripe Saturating little tomato(50 grams or so)Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, treats chopped spring onion Blow out fragrance when the tomato of chopping poured into decoct in pot fry 1-2 minutes, then infuse to be got away into suitable quantity of water and take the dish out of the pot.
The effect of each raw material of the present invention:
Curcuma zedoary, nature and flavorEffect:It is bitter, pungent, it is warm in nature.Promoting the circulation of qi blood-breaking, Xiao Ji Zhi Tong.It is clinicalUsing:It is mainly used in sonCervical carcinoma, also Suitable for other various tumours such as liver cancer,Cancer of the stomach, cancer of pancreas,Oophoroma, colon cancer, lung cancer,SkinCancer, leukaemia, essence are former thin Born of the same parents' cancer, lip cancer, carcinoma of vulva etc..Additionally, this product is additionally operable to treatment, and a lump in the abdomen causing distension and pain, gastral cavity abdomenDistending pain, dyspepsia distending pain, AmenorrheaStomachacheDeng.
Suddenly it is wooden, containing araloside suddenly, protocatechuic acid, choline and volatile oil etc..The property of medicine is sweet, pungent, puts down.Return liver, courage, stomach, large intestine, Lung, kidney channel.Drug effect:Internal heat anticance, anti-inflammatory detumescence, clearing damp Li Shui.Medicinal (1) internal heat anticance, for carcinoma product poison:Cholangiocarcinoma, Cancer of the stomach, the carcinoma of the rectum, lung cancer etc.;(2) anti-inflammatory detumescence, swells and ache for inflammation:Cystitis;(3) clearing damp profit fire, for edema caused by wind-dampness: Nephritic dropsy.Nature and flavorEffect:It is bitter, cold in nature.Heat-clearing and damp-drying drug, purging intense heat and detonicating.It is clinicalUsing:Suitable for various arsine knurls, such as liver, Courage tumour, tongue cancer, lip cancer, the cancer of the esophagus,Cancer of the stomach, carcinoma of urinary bladder etc..
Iron pierces Siberian cocklebur, nature and flavor:It is sweet;Acid;It is mild-natured.Return through:Liver ChannelKidney channel.Indication:Wines used as antirheumatic, diuresis, detumescence poison. Arthralgia is controlled, muscle is numb, has loose bowels, dysentery, oedema, gonorrhoea, furunculosis, pyogenic infections, scrofula, hemorrhoid.Jiangxi《Chinese herbology》:Solution Malicious wind-dispelling, is sore carbuncle key medicine.Control severe and migratory arthralgia gout(Rheumatoid arthritis), muscular paralysis, cancer of the esophagus, psoriasis.
Fourstamen Stephania Root, nature and flavorEffect:It is bitter, pungent, it is cold in nature.Inducing diuresis for removing edema, wind-expelling pain-stopping.It is clinicalUsing:Suitable for variousCancer, such as carcinoma of urinary bladder, lung cancer, liver cancer, kidney arsine knurl.Additionally, this product is additionally operable to rheumatism, oedema, arthritis, high blood pressure Deng.
Pellet feeds, nature and flavorEffect:Bitter, cold nature.Stasis-dispelling and pain-killing, promoting blood circulation for regulating menstruation, nourishing heart relieving restlessness.It is clinicalUsing:It is applied to The tumor in digestive tract accumulate in stagnation of QI-blood, heat toxin, is additionally operable to the osteosarcoma or bone metastaes of stasis channels and collaterals.Additionally, being usually used inTreatment irregular menstruation, Amenorrhea,Ectopic pregnancy, hepatosplenomegaly, angina pectoris, dysphoria and insomnia, sore swollen toxin.
Dark plum, nature and flavorEffect:Sour-puckery flavor, it is warm in nature.Astringe the lung puckery intestines, promote the production of body fluid to quench thirst.CanTreatmentCancerous swelling.It is clinically used for treatment Carcinoma of penis,Cervical carcinoma, colon and rectum carcinoma, the cancer of the esophagus,Cancer of the stomachDeng.Additionally, being additionally operable to treat chronic cough of deficiency lung, dry polydipsia, courage It is road roundworm, cholecystitis, bacillary dysentery, chronicDiarrhoea, Lu pass through many, psoriasis.External curing ulcer does not close up long, corn etc..
Chinese lobelia, is the herb of Campanulaceae Lobelia sessilifolia platymiscium Chinese lobelia.Its taste is pungent, slight bitter is mild-natured.Mainly contain Chinese lobelia Alkali (also known as antabac), secondly also contains cis-8,10-diphenyllobelidione (lobelanine), cis-8,10-diphenyllobelidiol (lobelanidine) Etc. various alkaloids and flavonoids, synanthrin, sodium succinate, fumaric acid, P-hydroxybenzoic acid sodium and phenols etc..Also contain soap Glucoside, amino acid etc..Function is clearing heat and detoxicating, inducing diuresis for removing edema.Cure mainly the diseases such as venomous snake bite, furunculosis furuncle, oedema, jaundice.Liver Cancer merges ascites, lung cancer;Additionally, Chinese lobelia is at aspects such as treatment colorectal cancer, nasopharyngeal carcinoma, cancer of the esophagus, cancer of the stomach, myeloma, brain tumors Also appear in the newspapers.In addition to antitumor action, Chinese lobelia Alkaloid has central excitation to act on, and is that important neural choline receptor is exciting Agent, it also has the multiple pharmacological effects such as diuresis, cholagogic, antibacterial, anti-inflammatory, anti-snake venom.
Arillus longan, it is sweet, warm in nature.Enter the heart, the spleen channel.Allay excitement with tonifying heart and spleen, blood-nourishing, invigorating the spleen to arrest diarrhea, inducing diuresis to remove edema etc. Effect.Suitable for body void after being ill, blood deficiency chlorosis, insufficiency of vital energy and blood,Neurasthenia, palpitation and severe palpitation, the illness such as forgetful insomnia.Effect with Effect:1st, blood-enrich, strengthens memory, containing the material that can provide heat energy in arillus longan, in these materials nutrition is converted into While, moreover it is possible to promote hematopoietic cell hematopoiesis, it is demonstrated experimentally that arillus longan is particularly advantageous to whole body and brain.2nd, tranquilizing the mind, dragon Eye meat contains the elements such as substantial amounts of iron, potassium, can promote the regeneration of hemoglobin to treat palpitaition, nervous, mistake because anaemia is caused Sleep, it is forgetful.2.5 milligrams (100 grams) are up to containing niacin in longan, can be used to treat what nicotinic acid deficiency was causedDermatitis, diarrhoea, Dementia, or even insane etc..3rd, nourishing blood and preventing abortion, arillus longan iron content and vitamin it is relatively more, uterine contraction and sagging sense can be mitigated, it is right It is favourable in the development of the pregnant woman and fetus that accelerate metabolism, with antiabortive effect.4th, antibacterial, inhibition cancer cell, once had it is demonstrated experimentally that Arillus longan can prevent certain tumour, can also extend the life-span with the generation of inhibition cancer cell.5th, lipid-loweringing shield heart, delays to decline Always, arillus longan can reducing blood lipid, increase coronary blood flow.Pair there is flavoprotein --- the brain B of substantial connection with aging course MAO-B B (MAO-B) has stronger inhibitory action.Arillus longan tonifying heart and spleen, nourishing blood and tranquilization.For insufficiency of vital energy and blood, palpitaition Palpitation, forgetful insomnia, blood deficiency chlorosis.The nutritive value of arillus longan is very high, and the elderly takes can protect blood vessel, and anti-hemostatic tube is hard Change.
Pseudo-ginseng, pseudo-ginseng is one of ten big Chinese herbal medicine for preventing, meridian distribution of property and flavor:Sweet, slight bitter, tepor, Return liver, stomach.Indication Removing blood stasis and hemostasis, activating blood circulation and reducing swelling analgesic therapy.It is clinicalOn applying clinical commonly use control lung cancer, the cancer of the esophagus,Cervical carcinomaBelong to stagnation of blood stasis etc. carcinoma Or and bleeder.Cure mainly it is various go out blood trouble, fall servant's stasis of blood swell, chest impediment and cardialgia.Arasaponin Rd can make the tumour cell 92% of culture It is suppressed, Rd also has obvious inhibiting effect to the oncocyte cultivated.Saponin Rhl can suppress murine melanoma(B16)Life Long, again induction is reversed into non-cancerous cells to make cancer cell.Pseudo-ginseng decoction has inhibitory action to JYC26 in vivo;In pseudo-ginseng Polysaccharide body can substantially suppress in vivo murine sarcoma -180;Pseudo-ginseng also has antiphagin activity.
Camplotheca acuminata, nature and flavorEffect:It is bitter, puckery, it is cold in nature, it is poisonous.Anticancer, dissipating bind, heat-clearing desinsection.It is clinicalUsing:It is applied to Kinds of tumors, the such as cancer of the esophagus,Cancer of the stomach, the carcinoma of the rectum, liver cancer, carcinoma of urinary bladder, adenocarcinoma ovaries, chronic granulocytic leukemia, acute pouring Bar cell leukemia, lymphosarcoma etc..
Walnut kernel, sweet, temperature.Return through:Enter lung, liver, kidney, large intestine channel.There are " benefiting qi and nourishing blood, moistening dryness and resolving phlegm, the beneficial gate of vitality, place Three is burnt, warm lung ease constipation, controls the cold of insufficiency type and breathes with cough, and waist pin aches again, trusted subordinate's colic, ease constipation, bloody flux intestines wind dry constipation of intestines, dry feces, mends Kidney controlling nocturnal emission with astringent drugs, warm lung Dingchuan, lung kidney deficiency, the cold of insufficiency type is breathed with cough, chronic cough of deficiency lung, asthma " the effects such as.Long-term consumption prolonging life and nursing face, anti-ageing Always, anticancer.
Radix Glycyrrhizae, root and root system master contain triterpenoid saponin, wherein main one kind is commonly called as glycyrrhizin, and the chemical combination of class containing flavonol Thing 4',7-Dihydroxyflavanone, liquiritin etc., also compound containing Coumarins Radix Glycyrrhizae coumarin, glycyol etc., separately gather containing alkaloid, Radix Glycyrrhizae Portugal The compounds such as sugared GBW.Sweet, mild-natured, returns spleen, stomach, the heart, lung channel, invigorating middle warmer and replenishing QI, relieving spasm to stop pain moistens the lung and relieve the cough, purging intense heat and detonicating, Coordinating the drug actions of a prescription.Burnout deficiency of food is cured mainly, the thin face of flesh is yellow, palpitation, loose stool of suffering from abdominal pain, four limbs contraction, hysteria, cough and asthma, Abscess of throat, ulcerative carbuncle pyogenic infections, infant fetal toxin and medicine, food poisoning.Radix Glycyrrhizae has removing toxic substances antibacterial action, and anti AIDS virus are made With, licorice polysaccharide in vitro to vesicular stomatitis virus, adenovirus II type, herpes simplex virus I type and vaccinia virus are equal There is obvious inhibiting effect, not only can directly inactivate this several virus, and also have effect to intracellular virus, additionally, sweet Grass also has Antitussive and Expectorant Effect, with anti-inflammatory, affects digestive system, immune system and cardiovascular system, antitumor and anti-prominent Change, corticotropin sample, anti-oxidant etc. are acted on.The acute and chronic viral hepatitis of clinical treatment, treatment diabetes, treatment Gastric and duodenal ulcer etc..The present invention is to the concocting method of Radix Glycyrrhizae:Extracting liquorice, except removing LU and impurity, size bar is separate, Be dipped to 3 four one-tenth it is saturating when, pick up and soften, cut sheet, be dried.
Tomato, tomato has fat-reducingWeight reducing, dispelling fatigue, improve a poor appetite, improve the digestion to protein, reduce stomach The effects such as swollen dyspepsia.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, before tomato always occupies Row.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the tomato in cancer-resisting is mostly derived from it In lycopene.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, tomato red Element can promote Carcinoma cell differentiation (to good direction conversion), inhibition cancer cell propagation.Second, immune function of human body can be strengthened.Kind Lycopene can promote some to have the cytokine secretion of anti-cancer, antitumaous effect, such as interleukins-II, activated lymphocyte pair The dissolution of cancer cell;The lymphocyte being activated can discharge cytokine such as TNF etc. again, have to tumour cell There is lethal effect.3rd, lycopene has strongerIt is anti-oxidantEffect.Cell it is aging, damage and canceration all and free radical Effect is relevant, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein just It is included in protective effect on cancer risk and plays an important role.
The effect of the present invention:
Cure mainly:The cancer of the esophagus, particularly the early stage cancer of the esophagus, with very low cost, fundamentally improve physical function, control tumour after Continuous overgrowing simultaneously makes it that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as throat cancer, cardiac cancer, pylorus cancer, cancer of the stomach, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug, dosage are moderate, do not waste.
2nd, selected flavour of a drug are all to be proved that for cancer the cancer of the esophagus particularly can be treated by modern medicine pharmacological evaluation 's.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by Modern medicine pharmacological evaluation proves function for cancer with effect.
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.Rather than only It is for cancer, just jump on the bandwagon, as a result it is that " dragon " does not harness the river on the contrary more.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.This Sample can just make patient suffer less within the cycle of whole medication, pull the devil by the tail less.And if really occurring " getting angry " or " under let out " Situation, then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition Certainly.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicine sides of being added to Son, makes patient all take always during very long very long medication, ultimately causes adverse consequences.
Specific embodiment:By curcuma zedoary 30g, neglect wood 30g, iron and pierce Siberian cocklebur 30g, Fourstamen Stephania Root 9g, pellet and feed 13g, dark plum 7g, one side of something Lotus 25g, arillus longan 15g, pseudo-ginseng 7g, camplotheca acuminata 7g respectively amplify 10 times, after clean water, are placed in BT-2 stainless steels and extract in kettle, plus After 7-9 times of running water, it is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Second Secondary extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, separation and Extraction Liquid, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature Extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is merged, B-500 is placed in In type triple effect vacuum high energy evaporation concentrator, reduce pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~ 1.20, it is standby.Powder processed:Walnut kernel 15g, Radix Glycyrrhizae 9g are respectively amplified 10 times, it is end together to crush, and crosses 100 mesh sieves, standby.Dispensing: In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.Dry Dry, crushing:The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Make Grain:The spice being well mixed is inserted in comminutor and is granulated.Whole grain:The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried: Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.Packaging:First by the pill for making In being fitted into vinyon pouch, every bag of 8-9g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, spoke It is 8kGy according to dosage).Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine art wood oesophagus holds back cancer particle and preparation method thereof, it is characterised in that it is by the raw material of following weight proportion Made by:
Curcuma zedoary 30g neglect wood 30g, iron pierce Siberian cocklebur 30g, Fourstamen Stephania Root 9g,
Pellet feed 13g, dark plum 7g, Chinese lobelia 25g, arillus longan 15g,
Pseudo-ginseng 7g, camplotheca acuminata 7g, walnut kernel 15g, Radix Glycyrrhizae 9g
This side is the substantially square of one decoction on the one, in practical application, can also be increased according to the physique of patient and conditions Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
2. the Hui ethnic group's Chinese medicine art wood oesophagus according to claim 1 holds back the weight proportion of cancer particle, it is characterised in that under including State preparation process:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to walnut kernel, Radix Glycyrrhizae 9g, all amplify 10 times, clean water Afterwards, BT-2 stainless steels are placed in extract in kettle, plus after 7-9 times of running water, 100 DEG C of constant temperature are heated to and are extracted 1 hour or so, separated Extract, pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature extraction half an hour left The right side, extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, Extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), 80 DEG C are heated to, relative density 1.10~1.20 is concentrated into, it is standby;
(3), powder processed
Walnut kernel 15g, Radix Glycyrrhizae 9g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stirring is equal It is even;
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves;
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated;
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed;
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C;
B, packaging
First the pill for making is fitted into vinyon pouch, every bag of 8-9g, then by the pouch mounted box for installing, vanning, sterilizing (60Co irradiation is adopted, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
CN201510749266.0A 2015-11-08 2015-11-08 Hui nationality traditional Chinese medicinal Rhizoma Curcumae and Araiia chinensis L. root bark esophagus cancer treatment granule and preparation method thereof Withdrawn CN106668703A (en)

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Application publication date: 20170517