CN106668649A - Hui-nationality traditional Chinese medicine pill with radix notoginseng for eliminating esophagus cancer and preparation method thereof - Google Patents

Hui-nationality traditional Chinese medicine pill with radix notoginseng for eliminating esophagus cancer and preparation method thereof Download PDF

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CN106668649A
CN106668649A CN201510749370.XA CN201510749370A CN106668649A CN 106668649 A CN106668649 A CN 106668649A CN 201510749370 A CN201510749370 A CN 201510749370A CN 106668649 A CN106668649 A CN 106668649A
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cancer
traditional chinese
pill
medicine
chinese medicine
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王学礼
王桂英
马芳
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Yinchuan Shanghetu New Technology Development Co Ltd
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Yinchuan Shanghetu New Technology Development Co Ltd
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Abstract

The invention specifically discloses a formula of a Hui-nationality traditional Chinese medicine pill with radix notoginseng for eliminating esophagus cancer and a preparation method thereof. The medicine is a green and high-tech traditional Chinese herbal medicine for treating esophagus cancer. The medicine is a traditional Chinese medicine pill prepared by mixing traditional Chinese herbal medicines such as radix notoginseng, herba sarcandrae, lignum sappan and sal ammoniacus and the like according to a certain ratio, adding water for decocting, extracting, concentrating and pilling. The traditional Chinese medicine pill is mainly used for treating esophagus cancer and is also used for treating digestive system cancers such as pharyngolaryngeal cancer, gastric cancer and colorectal cancer and the like. The traditional Chinese medicine pill has the characteristics of moderate amount of medicines and moderate dosage; the modern medical pharmacology experiments show that the selected traditional Chinese medicines can be used for treating cancers; the traditional Chinese medicine pill is low in cost and is capable of fundamentally improving physical functions as well as preventing cell canceration so as to restore physical health.

Description

Hui ethnic group's Chinese medicine pseudo-ginseng oesophagus pill for cancer-eliminating and preparation method thereof
Technical field
Hui ethnic group's Chinese medicine pseudo-ginseng oesophagus pill for cancer-eliminating according to the present invention is a kind of green high-tech of the prevention and treatment cancer of the esophagus Chinese herbal medicine.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, China The probability that people suffers from malignant tumour in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumour, tumour China into For a kind of common disease.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase. And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patient with esophageal carcinoma Account for the 29.7% of Alimentary System patient, almost half.
Cancer of the esophagusDisease locus typically organize in epithelium of esophagus, its directly impact be exactly that patient swallows and digest work( Can, health is slowly etched with regard to this.The pathogenic factor of cancer of the esophagus mainly has three, and one is malnutritive, though i.e. people now Living standard improve, but due to the change of diet hobby and mode, will also result in malnutritive and trace element lacking It is weary;Two is that diet is lack of standardization, and in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase, These materials are easily-synthesized carcinogen nitrosamine in stomach;Three be esophageal injury and disease induction, esophageal injury and some food Pipe disease is likely to become the inducement for causing cancer of the esophagus, is detained and cause long-term chronic inflammation, ulcer because of in oesophagus, or slowly Sexual stimulus, and then esophageal epithelial proliferation, finally result in canceration.Although cancer of the esophagus does not possess infectiousness, the destruction to human body But it is not allow to look down upon.
Though the early symptom of the cancer of the esophagus is more substantially, usual to be always mistakenly considered flu etc by people, therefore is often neglected Depending on, but do not know that the speed that cancer of the esophagus slowly deteriorates is very fast, once and feel increasingly apparent to be difficult to swallow, most likely Deteriorate as cancer.Afterwards may be by operation to the process of cancerization Regional resection, to reduce the death rate of cancer of the esophagus.
At present treatment cancer of the esophagus the best way is operation, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, suffer from Person's pain is difficult to stand, and success rate is also very low, and the life cycle after most Chemotherapy in Patients was with regard to 1 year or so --- certainly This is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some perform the operation, due to a variety of causes Hold and can't stand chemotherapy, can only palliative treatment, expect that miracle comes ...
The cancer of the esophagus is at present more refractory disease more as cancer of the stomach, all, but refractory representative cannot be controlled, except above-mentioned doctor trained in Western medicine Outside treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science is with organic conception according to the dialectical opinion of whole body feature of patient Control, go for various each phase cancer.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is light Micro-, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense Than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, Improve cancer related symptoms, improve life quality, extend life cycle.But the problem for existing is that the prescription uniformity of the traditional Chinese medical science is poor, Treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always have in selected Chinese herbal medicine medicinal material --- it is most It is more than more than half --- medicine is all not proved function for cancer and acted on by modern medicine pharmacological evaluation " to distinguish Card treat " " compatibility " medicine, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often delay control The time of disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatability Poor, high level evidence-based medicine EBM is theoretical and evidence is relative lacks, thus the situation for mainly waiting deficiency by rule of thumb for cancer, proposition one The new dosage of kind and preparation method, there is provided one kind reduces the incidence of disease of the cancer of the esophagus from the beginning of prevention, starts to subtract from canceration Delay its tempo, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one is special Shi Yongyu esophageal ulcer before cancer not treated in case its canceration, two is can to treat cancer just ulcer, in case it continues to deteriorate, three It is inducible into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improves physical function, so as to recover strong Health.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In tool In the formula of body, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, induced because of esophageal injury, disease according to the origin cause of formation of cancer of the esophagus, dietary preferences nutrition is lost Weighing apparatus causes immunologic hypofunction, causes normal cell to be compromised because of Helicobacter pylori infection, apoptosis, and digestive tract ulcer, canceration " are taken advantage of It is empty and enter ", because " weakened body resistance poison is poly- ", " void in healthy tendency " and the characteristics of cause the basic pathology interpretation of the cause, onset and process of an illness such as metastases, with or righting dispel Heresy, orTonification and purgation in combination, or regulating qi to disperse stagnation, or solve strongly fragrant resolving sputum, or clearing heat and detoxicating, or reinforcing and reducing methods and the method used, with correct void in healthy tendency, Poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjusts and improves the immunologic function of body, to reach overall tumor suppression Purpose, so as to improve the overall curative effect and late result of carninomatosis treatment, provides for esophageal cancer patients and a kind of is cured by modern Learn green high-tech Chinese herbal medicine formula and compound method that pharmacological evaluation proves function for cancer and effect, with very low or Relatively low cost, fundamentally improves physical function, and the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and the final body that recovers is good for Health.Thus also to patient one according to the personal state of an illness, economic situation, personal inclination come consider select different treatment methods or Several method shares particularly traditional Chinese and western medicine and combines the leeway of complex treatment application, to obtaining optimum curative effect, easily improves life Deposit rate --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
First, Hui ethnic group's Chinese medicine pseudo-ginseng oesophagus pill for cancer-eliminating of the described prevention and treatment cancer of the esophagus and preparation method thereof, is by following heavy Made by amount proportioning raw material:
Pseudo-ginseng 9g, Glabrous Sarcandra Herb 30g, bush 9g, red sage root 15g,
Lu sand 1g, iron thorn Siberian cocklebur 30g, fringed pink 9g, tuber of pinellia 7g,
Bighead atractylodes rhizome 30g, hairyvein agrimony 12g, Radix Rabdosiae glaucocalycis 30g
This side is substantially square for one decoction on the one.In practical application, can also be increased according to the physique of patient and conditions Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must apply special process It is prepared.
2nd, it is by the preparation method that above-mentioned each raw material makes medicine pill of the present invention:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the red sage root, all amplify 10 times, after clean water, be placed in BT- 2 stainless steels are extracted in kettle, plus after 7-9 times of running water, are heated to 100 DEG C of constant temperature and are extracted 1 hour or so, extraction fluid, plus Press filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract half an hour Left and right, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes Left and right, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), 80 DEG C are heated to, relative density 1.10~1.20 is concentrated into, it is standby.
(3), powder processed
Red sage root 15g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stirring is equal It is even.
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated.
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed.
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.
(9), pill
Dry mixed gained medicine is put into pill in Chinese medicinal pills preparing machine, pill is optimal with below 4mm.
B, packaging
First the pill for making is fitted into vinyon pouch, every bag of 6-8g, then by the pouch mounted box for installing, vanning, sterilizing (60Co irradiation is adopted, irradiation dose is 8kGy).
, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Three times a day, every time 1 bag, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down Liquid).This medicine does medicine efficacy enhancing ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is:Take from so well-done Little tomato(50 grams or so)Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, treats that chopped spring onion floats When going out fragrance the tomato of chopping is poured into be decocted in pot and fry 1-2 minutes, then infuse to be got away into suitable quantity of water and take the dish out of the pot.During medication not Eat the pungent grade food larger to gastrointestinal irritation.
The effect of each raw material of the present invention:
Pseudo-ginseng, pseudo-ginseng is one of ten big Chinese herbal medicine for preventing, meridian distribution of property and flavor:Sweet, slight bitter, tepor, Return liver, stomach.Indication stagnation resolvation Hemostasis, activating blood circulation and reducing swelling analgesic therapy.It is clinicalOn applying clinical commonly use control lung cancer, the cancer of the esophagus,Cervical carcinomaBelong to stagnation of blood stasis or simultaneous etc. carcinoma Bleeder.Cure mainly it is various go out blood trouble, fall servant's stasis of blood swell, chest impediment and cardialgia.Arasaponin Rd is subject to the tumour cell 92% of culture Suppress, Rd also has obvious inhibiting effect to the oncocyte cultivated.Saponin Rhl can suppress murine melanoma(B16)Growth, make Again induction is reversed into non-cancerous cells to cancer cell.Pseudo-ginseng decoction has inhibitory action to JYC26 in vivo;Polysaccharide body in pseudo-ginseng Murine sarcoma -180 can substantially be suppressed in vivo;Pseudo-ginseng also has antiphagin activity.
Glabrous Sarcandra Herb, nature and flavorEffect:Taste is pungent, it is mild-natured.It is clearing heat and detoxicating, dispelling wind and eliminating dampness, promoting blood circulation and stopping pain.It is clinicalUsing:It is applied to Kinds of tumors, the such as cancer of the esophagus,Cancer of the stomach, colon and rectum carcinoma, cancer of pancreas, liver cancer, acute leukemia etc..
Bush, nature and flavorEffect:It is sweet, salty, mild-natured.Promoting circulation of blood broken stasis of blood, swelling and pain relieving.It is clinicalUsing:This product is closely used to disappear Change road arsine knurl andCervical carcinomaOophoroma, liver cancer and chronic myelogenous leukemia.Additionally, being additionally operable toTreatmentAmenorrheaStomachachePostpartumThe stasis of blood Blood, suffer from abdominal pain uncomfortable in chest, traumatic injury, knife wound bleeding, icteric hepatitis, La diseases, orchitis,Anaemia, afterpains.Furuncle pain, urine Road feel dye, renal shutdownPain in the back, chronic enteritis, enterorrhagia, haematemesis etc..
The red sage root, bitter, micro-pungent, cold nature;The heart, spleen, liver, the medicine of kidney blood system.Be the Labiatae herbaceous plant red sage root root and Rhizome.With promoting blood circulation and removing blood stasis, nourishing blood and tranquilization, effect of cool blood detumescence.The red sage root contains tanshinone, protocatechualdehyde, protocatechuic acid, the red sage root Element, vitamin E etc., cure mainly hemostasis head, chest, the side of body, abdomen pain, accumulation, irregular menstruation,DysmenorrhoeaAmenorrhea, postpartum stasis of blood, joint Numbness pain, beat the stasis of blood swell, warm disease is vexed, palpitation due to deficiency of blood, sore swollen toxin, red rash mange.
Sal ammoniac, the crystal of halogenation species mineral sal ammoniac.Nature and flavorEffect:Taste is salty, bitter, pungent, warm in nature, poisonous.Disappear long-pending softening hard masses, Drastically removing blood stasis and resolving static blood.It is clinicalUsing:Suitable for kinds of tumors, such as the cancer of the esophagus,SkinCancer, nasopharyngeal carcinoma,Cervical carcinomaDeng.Additionally, being additionally operable to Amenorrhea, phlegm and retained fluid, larynx numbness, product dysentery, mesh screen, polyp, wart, furunculosis, carbuncle swells, evil sore etc..
Iron pierces Siberian cocklebur, nature and flavor:It is sweet;Acid;It is mild-natured.Return through:Liver ChannelKidney channel.Indication:Wines used as antirheumatic, diuresis, detumescence poison. Arthralgia is controlled, muscle is numb, has loose bowels, dysentery, oedema, gonorrhoea, furunculosis, pyogenic infections, scrofula, hemorrhoid.Jiangxi《Chinese herbology》:Solution Malicious wind-dispelling, is sore carbuncle key medicine.Control severe and migratory arthralgia gout(Rheumatoid arthritis), muscular paralysis, cancer of the esophagus, psoriasis.
Fringed pink, nature and flavorEffect:Bitter, it is cold in nature.Heat-clearing, diuresis, blood-breaking is stimulated the menstrual flow.It is clinicalUsing:Suitable for kinds of tumors, As carcinoma of urinary bladder,Cancer of the stomach, the cancer of the esophagus,UterusCancer and the carcinoma of the rectum etc..
The tuber of pinellia, nature and flavor:Taste is pungent;It is warm in nature;It is poisonous.Return through:The spleen channel;Stomach;Lung channel.Effect:It is eliminating dampness and eliminating phlegm;Stopping nausea and vomiting by lowering the adverse flow of QI;Disappear ruffian Dissipating bind.Cure mainly:Cough and phlegm;Vomiting gastric disorder causing nausea;Feeling of oppression and fullness in the chest and epigastrium dizziness of having a headache;Uneasy sleeping at night;Gall subcutaneous nodule;Swollen ulcer drug.Effect: Dried pinellia:Crude drug is taken, impurity is removed, cleaning, drying, the used time smashs to pieces.It is poisonous, many external applications, based on swelling and pain relieving.Method half Summer:It is longer than eliminating dampness, and warm nature is low.The lime tuber of pinellia, for abundant expectoration cough and asthma, phlegm retention anti-dazzle nervous, anemophlegmatic vertigo, phlegm and headache.Control cold Based on phlegm, damp phlegm, while with the effect for adjusting spleen and stomach.Prepared RHIZOMA PINELLIZE without adju-vant:It is longer than resolving sputum.Alum soaks or boils or pickle.Eliminate The side effect of pungent thorn larynx, reduces toxicity, based on eliminating dampness and eliminating phlegm.Function cures mainly eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, and the ruffian that disappears dissipates Knot.Wet phlegm and cold drink is controlled, is vomitted, gastric disorder causing nausea, cough and phlegm, fullness in chest, phlegm and headache, dizziness and sleepless.Outer subduing inflammation.Pinellia: It is longer than stopping nausea and vomiting by lowering the adverse flow of QI.Ginger alum boils or pickles or steam, or ginger is fried.Middle benefit gas resolving sputum, based on stopping nausea and vomiting by lowering the adverse flow of QI.Function with cure mainly:Drop is inverse Preventing or arresting vomiting.For vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus.Rhizoma Pinelliae Fermentata:It is longer than and eliminates indigestion and phlegm.Levigation, ginger are dried in dried pinellia immersion Juice, flour are mixed well, and fermentation is made.Dampness elimination invigorating the spleen, help digestion antidiarrheal.The bamboo juice tuber of pinellia:The tuber of pinellia or rhizoma pinellinae praeparata, bamboo juice is mixed and dried in the shade.Temperature It is dry to subtract greatly, gastropyretic vomiting is suitable to, lung heat yellow and sticky sputum closes aphasia from apoplexy in phlegm heat.
The bighead atractylodes rhizome, the bighead atractylodes rhizome is the key medicine of air making-up and spleen enlivening, for controlling syndrome of deficiency of spleen qi and stomach qi, splenasthenic diarrhea, indigestion, stomach and intestine disease Suffer from, for controlling and middle tonifying spleen, dehumidify beneficial gas, in being assigned in tonic side, fills blood.The bighead atractylodes rhizome both can air making-up and spleen enlivening, again can eliminate dampness and have diuretic effect, Therefore to control the good medicine of phlegm and retained fluid oedema, for controlling various oedema (such as renal, gestational, trophoedema).Bighead atractylodes rhizome beneficial gas tonifying spleen, There is strengthening exterior and reducing sweat to act on, for controlling exterior deficiency spontaneous perspiration, arthritis rheumatalgia.Bighead atractylodes rhizome air making-up and spleen enlivening, and have antiabortive effect, for controlling tire Dynamic uneasiness.The effect of the bighead atractylodes rhizome mainly has calmness, blood vessel dilatation, anticoagulant, anti-gastric-ulcer, hepatic cholagogic, diuresis, strong, raising Immune, anti-oxidant, antibacterial and antitumor etc..Bighead atractylodes rhizome invigorating the spleen to dry is good, the multiplex life of eliminate dampness and have diuretic effect.Bighead atractylodes rhizome sweetness and bitterness temperature is nontoxic, Gu table Hidroschesis disappears five cereals.Fetal irritability controls phlegm wet, and splenasthenic diarrhea all can take.
Hairyvein agrimony, nature and flavor are bitter, puckery, put down.The thoughts of returning home, Liver Channel.Indication:Astringing to arrest bleeding, preventing malaria, only dysentery, detoxifies.For coughing Blood, spits blood, metrostaxis, malaria, bloody flux, de-power internal lesion caused by overexertion, carbuncle sore tumefacting virus, pruritus vulvae under band.Early in the Ming Dynasty, China physician Jiang Yi Just willHairyvein agrimonyFor treatingCancer of the esophagusWithCancer of the stomach.He writes in curing:" rolling pharynx every phlegm, flat regurgitation it is dirty ", swallow every turning over Stomach be ancients to describe the illness of cancer of the esophagus and cancer of the stomach, " always doctor's faciation fear, think incurable disease." " it is remaining to obtain this agent, Ten throw nine imitates ".CancerPatient is taken after hairyvein agrimony, such as " grain of famine, the fur coat in midwinter ".Modern medicine study discovery, hairyvein agrimony Extract at least contains 12 kinds of compositions, and its major part is in cancer resistance.
Radix Rabdosiae glaucocalycis, nature and flavor are sweet, bitter, cool in nature.Indication:It is clearing heat and detoxicating, stasis-dispelling and pain-killing.Main venomous snake bite, boil swells Poison, muscles and bones is ached, traumatic injury, burn and scald, invigorating the spleen, promoting blood circulation, controls gastritis, and hepatitis is from the beginning of cold, fever, Amenorrhea, mastitis is closed Section pain.Japan's plectranthin of proposition from Rabdosia amethystoides has antitumor action.
Tomato, tomato has fat-reducingWeight reducing, dispelling fatigue, improve a poor appetite, improve the digestion to protein, reduce stomach The effects such as swollen dyspepsia.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, before tomato always occupies Row.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the tomato in cancer-resisting is mostly derived from it In lycopene.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, tomato red Element can promote Carcinoma cell differentiation (to good direction conversion), inhibition cancer cell propagation.Second, immune function of human body can be strengthened.Kind Lycopene can promote some to have the cytokine secretion of anti-cancer, antitumaous effect, such as interleukins-II, activated lymphocyte pair The dissolution of cancer cell;The lymphocyte being activated can discharge cytokine such as TNF etc. again, have to tumour cell There is lethal effect.3rd, lycopene has strongerIt is anti-oxidantEffect.Cell it is aging, damage and canceration all and free radical Effect is relevant, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein just It is included in protective effect on cancer risk and plays an important role.
The effect of the present invention:
Cure mainly:The cancer of the esophagus, particularly the early stage cancer of the esophagus, with very low cost, fundamentally improve physical function, control tumour after Continuous overgrowing simultaneously makes it that final disappearance is gradually reduced, so as to recover healthy.It is simultaneous to control:Throat cancer, cardiac cancer, pylorus cancer, cancer of the stomach, The cancer in digestive system such as colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug, dosage are moderate, do not waste.
2nd, selected flavour of a drug are all to be proved that for cancer the cancer of the esophagus particularly can be treated by modern medicine pharmacological evaluation 's.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by Modern medicine pharmacological evaluation proves function for cancer with effect;
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.Rather than only It is for cancer, just jump on the bandwagon, as a result it is that " dragon " does not harness the river on the contrary more.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.This Sample can just make patient suffer less within the cycle of whole medication, pull the devil by the tail less.And if really occurring " getting angry " or " under let out " Situation, then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition Certainly.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicine sides of being added to Son, makes patient all take always during very long very long medication, ultimately causes adverse consequences.
Specific embodiment:By pseudo-ginseng 9g, Glabrous Sarcandra Herb 30g, bush 9g, Lu sand 1g, iron thorn Siberian cocklebur 30g, fringed pink 9g, the tuber of pinellia 7g, bighead atractylodes rhizome 30g, hairyvein agrimony 12g, Radix Rabdosiae glaucocalycis 30g respectively amplify 10 times, after clean water, are placed in BT-2 stainless steels and extract kettle In, plus after 7-9 times of running water, be heated to 100 DEG C of constant temperature and extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby. Extract for second:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, separation is carried Liquid is taken, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of perseverances Temperature is extracted 20 minutes or so, and extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is merged, B- is placed in In 500 type triple effect vacuum high energy evaporation concentrators, reduce pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10 ~1.20, it is standby.Powder processed:Red sage root 15g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby.Dispensing:In 300,000 grades of cleanings In workshop, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.Drying, crushing:Will mixing Uniform spice is placed in 60-70 DEG C of baking 4-5 hour in baking oven, then crushes, and crosses 100 mesh sieves.Granulation:By what is be well mixed Spice is inserted in comminutor and granulated.Whole grain:The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried:Whole good particle is inserted In heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.Pill:Dry mixed gained medicine is put into Chinese medicinal pills preparing machine Middle pill, pill is optimal with below 4mm.Packaging:First the pill for making is fitted into vinyon pouch, every bag of 6-8g, then The pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).Finally, by irradiated finished product Put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine " pseudo-ginseng oesophagus pill for cancer-eliminating " and preparation method thereof, it is characterised in that it is by the raw material of following weight proportion Made by:
Pseudo-ginseng 9g, Glabrous Sarcandra Herb 30g, bush 9g, red sage root 15g,
Lu sand 1g, iron thorn Siberian cocklebur 30g, fringed pink 9g, tuber of pinellia 7g,
Bighead atractylodes rhizome 30g, hairyvein agrimony 12g, Radix Rabdosiae glaucocalycis 30g
This side is the substantially square of one decoction on the one, in practical application, can also be increased according to the physique of patient and conditions Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
2. the weight proportion of Hui ethnic group's Chinese medicine " pseudo-ginseng oesophagus pill for cancer-eliminating " according to claim 1 and preparation method thereof, it is special Levy is to include following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the red sage root, all amplify 10 times, after clean water, be placed in BT- 2 stainless steels are extracted in kettle, plus after 7-9 times of running water, are heated to 100 DEG C of constant temperature and are extracted 1 hour or so, extraction fluid, plus Press filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, Extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, Extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), 80 DEG C are heated to, relative density 1.10~1.20 is concentrated into, it is standby;
(3), powder processed
Red sage root 15g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stirring is equal It is even;
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves;
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated;
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed;
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C;
(9), pill
Dry mixed gained medicine is put into pill in Chinese medicinal pills preparing machine, pill is optimal with below 4mm;
B, packaging
First the pill for making is fitted into vinyon pouch, every bag of 6-8g, then by the pouch mounted box for installing, vanning, sterilizing (60Co irradiation is adopted, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
CN201510749370.XA 2015-11-08 2015-11-08 Hui-nationality traditional Chinese medicine pill with radix notoginseng for eliminating esophagus cancer and preparation method thereof Withdrawn CN106668649A (en)

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Application publication date: 20170517