CN106668311A - Hui-nationality traditional Chinese medicine granule with radix pseudostellariae for treating gastric cancer and preparation method thereof - Google Patents

Hui-nationality traditional Chinese medicine granule with radix pseudostellariae for treating gastric cancer and preparation method thereof Download PDF

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CN106668311A
CN106668311A CN201510749979.7A CN201510749979A CN106668311A CN 106668311 A CN106668311 A CN 106668311A CN 201510749979 A CN201510749979 A CN 201510749979A CN 106668311 A CN106668311 A CN 106668311A
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cancer
traditional chinese
medicine
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chinese medicine
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王学礼
王桂芳
马芳
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Yinchuan Shanghetu New Technology Development Co Ltd
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Abstract

The invention specifically discloses a formula of a Hui-nationality traditional Chinese medicine granule with radix pseudostellariae for treating gastric cancer and a preparation method thereof. The medicine is a green and high-tech traditional Chinese herbal medicine for treating late gastric cancer, especially the late gastric cancer which cannot be operated because of various reasons. The medicine is a traditional Chinese medicine granule prepared by mixing traditional Chinese herbal medicines such as radix pseudostellariae, radix salviae miltiorrhizae, root of camptotheca acuminate, fructus ligustri lucidi, herba agrimoniae and entada sten and the like according to a certain ratio, adding water for decocting, extracting, concentrating and granulating. The traditional Chinese medicine granule is mainly used for treating gastric cancer and is also used for treating digestive system cancers such as pharyngolaryngeal cancer, esophagus cancer, cardiac cancer and colorectal cancer and the like. The traditional Chinese medicine granule has the characteristics of light medicine and moderate dosage; the modern medical pharmacology experiments show that most of the selected traditional Chinese medicines can be used for treating cancers.

Description

Hui ethnic group's Chinese medicine crown prince's cancer of the stomach recovering particles and preparation method thereof
Technical field
Hui ethnic group's Chinese medicine crown prince cancer of the stomach recovering particles according to the present invention are a kind of to treat late gastric cancer especially because the green high-tech Chinese herbal medicine of late gastric cancer that cannot be performed the operation of a variety of causes.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, Chinese all one's life suffer from malignant tumour probability be 22%, average minute clock has 6 people to be diagnosed as malignant tumour, and tumour has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patients with gastric cancer accounts for the 41.83% of Alimentary System patient, almost half.
China is one of incidence gastric cancer rate highest country, and the whole world is annual newly to send out patients with gastric cancer more than 100 ten thousand, and China just account for 42%, and death toll China has accounted for 35%, and the M & M of Chinese cancer of the stomach is world average level more than 2 times!Inherent cause among these, immune factor, helicobacter pylori infections factor are all nothing difficult, and most anxious is then environment and dietary factor ...
The early symptom of cancer of the stomach is not obvious, generally needs time of 2 years or so from incidence gastric cancer to finding tumour, therefore often ignored, once and to standing, most likely reach an advanced stage.
It is operation to control cancer of the stomach the best way at present, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, 1 year life cycle after most Chemotherapy in Patients less than --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some are detected to be cancer of the stomach, because a variety of causes cannot be performed the operation,Can only palliative treatment, expect that miracle comes ...
Cancer of the stomach is at present more refractory disease more, but refractory representative cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science, according to the whole body feature diagnosis and treatment of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " diagnosis and treatment based on an overall analysis of the illness and the patient's condition " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medicinal material, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatable poor, high level evidence-based medicine EBM be theoretical and the relative shortage of evidence,Thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided one kind reduces the incidence of disease of cancer of the stomach from the beginning of prevention, start to slow down its tempo from canceration, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one be particularly suited for use in treatment cancer before larger gastric ulcer in case its canceration, two is the especially big gastric ulcer that can treat the cancer of the stomach initial stage, in case it continues to deteriorate, three are can induce into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In specific formula, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, according to the origin cause of formation of cancer of the stomach because dietary factor makes nutrient disequilibrium cause immunologic hypofunction, because Helicobacter pylori infection causes stomach normal cell to be compromised, apoptosis, gastritis, digestive tract ulcer, lymphoproliferative gastric lymphoma " is taken advantage of a weak point " evil poison positive pressure, flee channels and collaterals visitor the characteristics of internal organs form long product and cause the basic pathology interpretation of the cause, onset and process of an illness such as Metastasis of Gastric Cancer because evil poison being tied in sick protracted blood stasis and being wrapped hemostasis and is taken advantage of a weak point in opponent's defence, with the tonifying speen and tonifying kidney strengthening vital QI to eliminate pathogenic factors method that tonification and purgation in combination, it is empty in healthy tendency to correct, poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjust and improve the immunologic function of body.Simultaneously according to the concrete condition of patient, different formulas, or easypro liver and stomach, drop check pain, or detoxification and removing stasis, clearing heat and nourishing yin, or warming spleen and stomach for dispelling cold, strengthening the spleen and stomach, or strongly invigorating QI and blood are respectively adopted, strengthening spleen, tonifying kidney ... is reachingTonification and purgation in combination, reinforcing and reducing methods and use, the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of curing gastric cancer, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for patients with gastric cancer, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and finally recovers healthy.Thus also to patient one select different treatment methods or several method to share particularly traditional Chinese and western medicine to combine the leeway of complex treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
Hui ethnic group's Chinese medicine crown prince's cancer of the stomach recovering particles of the first, described treatment cancer of the stomach are by made by following weight proportion raw material:
Radix pseudostellariae 25g, root of three-nerved spicebush 9g, Chinese lobelia 20g, fiveleaf akebia fruit 20g,
Phoenix-tail fern 25g, pellet feed 13g, camplotheca acuminata 7g, fruit of glossy privet 15g,
Hairyvein agrimony 9g, sophora flower 20g, celebrating bar are passed the summer in a leisurely way 1g, tomato 50g
This side is substantially square for one decoction on the one.In practical application, also the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory can be increased according to the physique of patient and conditionsDialectical compatibility " medicine.
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.
2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal granule of the present invention:
A, extract preparation
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the root of three-nerved spicebush, camplotheca acuminata, tomato, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.
(3), powder processed
Camplotheca acuminata 7g, root of three-nerved spicebush 9g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated.
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed.
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.
B, packaging
First pack, the particle by made by is fitted in polyethylene plastic bag, every bag of 7-8g.Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Above-mentioned particle three times a day, 1 bag of 7-8g every time, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.This medicine is a course for the treatment of in three months, typically takes two to three courses for the treatment of, at most takes four courses for the treatment of.
This medicine does medicine efficacy enhancing ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is:Take from so well-done little tomato(50 grams or so)Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, pours into be decocted in pot by the tomato of chopping when chopped spring onion blows out fragrance and fries 1-2 minutes, then infuses to be got away into suitable quantity of water and take the dish out of the pot.The pungent grade food larger to gastrointestinal irritation is not eaten during medication.
The effect of each raw material of the present invention:
Radix pseudostellariae,Mild in medicine property and, it is sweet, play the role of tonifying Qi and promote the production of body fluid.Qi-restoratives medicine, Qi-tonifying drug.Effect:Help spleen and lung, nourishing generate fluid.Control the deficiency syndrome of the lungCough, spleen eating less, palpitaition, palpitation, oedema quenches one's thirst, metal fatigue.For deficiency-weakness of spleen-QI, deficiency of stomach-Yin, deficiency of food body is tired, and thirsty tongue is done;Deficiency syndrome of the lung cough caused by dryness, dry throat phlegm glues;Deficiency of both vital energy and Yin, palpitation and insomnia.It is usually used in weakness of the spleen and the stomach, lassitude hypodynamia, poor appetite, dry cough few phlegm, after being ill body void, night sweat.Experimental study also demonstrates that radix pseudostellariae can improve immunologic function, improve heart function.
The root of three-nerved spicebush,Flavor efficacy:Ye Xin, it is warm in nature.Warming spleen and stomach for dispelling cold, regulating qi-flowing for relieving pain.Clinical practice:Closely it is used for tumor in digestive tract, such asCancer of the stomach, intestinal cancer, be additionally operable to carcinoma of urinary bladder etc..Additionally, being additionally operable toTreatmentHeart peratodynia, vomiting and diarrhoeaStomachacheDysmenorrhoea, colic, frequent micturition, rheumatalgia pain, injuries from falls as well and traumatism and bleeding.
Chinese lobelia ,For the herb of Campanulaceae Lobelia sessilifolia platymiscium Chinese lobelia.Its taste is pungent, slight bitter is mild-natured.Main (also known as antabac) containing lobeline, secondly also containing various alkaloids and flavonoids, synanthrin, sodium succinate, fumaric acid, P-hydroxybenzoic acid sodium and phenols etc. such as cis-8,10-diphenyllobelidione (lobelanine), cis-8,10-diphenyllobelidiols (lobelanidine).Also containing saponin, amino acid etc..Function is clearing heat and detoxicating, inducing diuresis for removing edema.Cure mainly the diseases such as venomous snake bite, furunculosis furuncle, oedema, jaundice.Combined with liver cancer ascites, lung cancer;Additionally, Chinese lobelia also appears in the newspapers at aspects such as treatment colorectal cancer, nasopharyngeal carcinoma, cancer of the esophagus, cancer of the stomach, myeloma, brain tumors.In addition to antitumor action, Chinese lobelia Alkaloid has central excitation to act on, and is important neural cholinergic receptor agonist, and it also has the multiple pharmacological effects such as diuresis, cholagogic, antibacterial, anti-inflammatory, anti-snake venom.
Fiveleaf akebia fruit,ForLardizabalaceaePlantAkebi threeleaf akebiaOrAkebia trifoliata varaustralisDry mature fruit.It is sweet, cold in nature, function isDispersing stagnated hepatoqi, promoting blood circulation and stopping pain, relieving restlessness diuresis.Cure mainlyStomachache due to emotional depression and the hyperactive liver-qi attacking the stomachStomach energyFood is slow-witted, polydipsia,DysenteryPain in the backHypochondriac pain, hernia etc..The less single of fiveleaf akebia fruit is used for kinds of tumors with his medicine phases 5 more with controlling in tumour, and has preferable curative effect more.
Pellet feeds,Nature and flavorEffect:Bitter, cold nature.Stasis-dispelling and pain-killing, promoting blood circulation for regulating menstruation, nourishing heart relieving restlessness.It is clinicalUsing:Suitable for the tumor in digestive tract accumulate in stagnation of QI-blood, heat toxin, the osteosarcoma or bone metastaes of stasis channels and collaterals are additionally operable to.Additionally, being usually used inTreatment irregular menstruation, Amenorrhea,Ectopic pregnancy, hepatosplenomegaly, angina pectoris, dysphoria and insomnia, sore swollen toxin.
Camplotheca acuminata,Nature and flavorEffect:It is bitter, puckery, it is cold in nature, it is poisonous.Anticancer, dissipating bind, heat-clearing desinsection.
It is clinicalUsing:Suitable for kinds of tumors, such as the cancer of the esophagus,Cancer of the stomach, the carcinoma of the rectum, liver cancer, carcinoma of urinary bladder, adenocarcinoma ovaries, chronic granulocytic leukemia, acute lymphatic leukemia, lymphosarcoma etc..
The fruit of glossy privet,Effect:Tonifying liver kidney yin, crow must improving eyesight.Drug effect:For the deficiency of liver-yin and kidney-yin, secretly not clear, hypopsia, mesh are secretly failed to understand for Light-headedness, seminal emission tinnitus, soreness and weakness of waist and knees, mesh, control fever due to yin deficiency, poliosis, tumour, soreness of waist tinnitus and fever due to yin deficiency etc..This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, must slowly take effect, treatmentCoronary heart disease, hyperlipidemia, hypertension, chronic hepatitis etc..
Hairyvein agrimony,Nature and flavor are bitter, puckery, put down.The thoughts of returning home, Liver Channel.Indication:Astringing to arrest bleeding, preventing malaria, only dysentery, detoxifies.For hemoptysis, spit blood, metrostaxis, malaria, bloody flux, de-power internal lesion caused by overexertion, carbuncle sore tumefacting virus, pruritus vulvae under band.Early in the Ming Dynasty, China physician Jiang Yi just willHairyvein agrimonyFor treatingCancer of the esophagusWithCancer of the stomach.He writes in curing:" rolling pharynx every phlegm, flat regurgitation it is dirty ", swallow every regurgitation be ancients to describe the illness of cancer of the esophagus and cancer of the stomach, " always doctor's faciation fear, think incurable disease." " remaining to obtain this agent, ten throw nine imitates ".CancerPatient is taken after hairyvein agrimony, such as " grain of famine, the fur coat in midwinter ".Modern medicine study finds that hairyvein agrimony extract at least contains 12 kinds of compositions, and its major part is in cancer resistance.
Sophora flower, nature and flavorHardship, is slightly cold.Return liver, large intestine channel.Effect:Cooling blood and hemostasis, clears liver and improve vision.It is additionally operable to the dizziness and headache of liver-fire flaming(It has certain hypotensive activity to modern study, and especially cold fragrant glycosides, is called rutin, can reduce the permeability of capillary, reduces the fragility of blood vessel, there is good protective effect to blood vessel, is less prone to cerebrovas-cularaccident bleeding), fundus oculi disease all can use.Effect:1. cooling blood and hemostasis, for blood-head blood trouble is gone out.Such as haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, hemorrhoid blood.The cold and bitter drop of this product, Return liver, large intestine channel are kind to let out large intestine burning hot clearly and cooling blood and hemostasis, therefore to treat bottom bleeding to be good at, and such as hemorrhoid blood, have blood in stool.Treating hematochezia, often matches somebody with somebodySchizonepetaCacumen biotaeEquivalent is used.Haematemesis, bleeding from five sense organs or subcutaneous tissue are controlled, is then often matched somebody with somebodyCogongrass rhizomeEquivalent is used.2. clearing away the liver-fire, for headache alliteration, hot eyes, the dizziness etc. of liver-fire flaming.Modern clinic is also commonly used for hypertension and belongs to the partially prosperous person of irascibility, the work(of step-down of clearing liver and improving vision.This product contains rutin sophorin, sophora flower A prime, B prime, C prime, tannin.The permeability and fragility of capillary can be reduced, shortens the bleeding time, strengthen the resistance of capillary.Have it is hypotensive, prevent and treat artery sclerosis, expand coronary vasodilator, improve myocardial circulation etc. effect.This product has anti-inflammatory, antibacterial, permeability and fragility antiviral, that can reduce capillary, shortens the bleeding time;Strengthen the resistance of capillary;Lowering blood pressure and blood fat, artery sclerosis is prevented and treated, there is expansion coronary vasodilator, improve the effect such as myocardial circulation.The cold and cool and bitter drop of this product, it is kind clearly to let out liver, stomach, the heat of large intestine and cooling blood and hemostasis, it is good at especially and treats hemorrhoid blood, has blood in stool.
Celebrating bar is passed the summer in a leisurely way,Nature and flavorEffect:Gan Liang is clearing heat and detoxicating.It is clinicalUsing:Anticancer, desinsection, the spiral shell that goes out, emetic rush down.
Tomato,Tomato has fat-reducing Weight reducing , dispelling fatigue, improve a poor appetite, improve the digestion to protein, reduce gasteremphraxis dyspepsia the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, tomato always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the tomato in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction conversion), inhibition cancer cell propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have the cytokine secretion of anti-cancer, antitumaous effect, such as interleukins-II, dissolution of the activated lymphocyte to cancer cell;The lymphocyte being activated can discharge cytokine such as TNF etc. again, have lethal effect to tumour cell.3rd, lycopene has stronger It is anti-oxidant Effect.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein be just included in protective effect on cancer risk playing an important role.
The effect of the present invention:
Cure mainly:Cancer of the stomach, especially because a variety of causes cannot carry out the late gastric cancer of Surgery for Gastric Carcinoma, with very low cost, fundamentally improves physical function, and control tumour continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as throat cancer, the cancer of the esophagus, cardiac cancer, pylorus cancer, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug are more, and dosage is moderate, do not waste.
2nd, selected flavour of a drug are mostly that proved by modern medicine pharmacological evaluation can be for cancer, and existing proved recipe for cancer, then always there are medicines more than half to be all not proved function for cancer and effect by modern medicine pharmacological evaluation in folk prescription.
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, being as a result that " dragon " is more bad on the contrary harnesses the river.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, add a bit " stopping leak ", the medicine of " fall fire " dialectically temporarily and specifically solve.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequences.
Specific embodiment:Radix pseudostellariae 25g, Chinese lobelia 20g, fiveleaf akebia fruit 20g, phoenix-tail fern 25g, pellet 13g, fruit of glossy privet 15g, hairyvein agrimony 9g, sophora flower 10g, the celebrating bar 1g that passes the summer in a leisurely way that feeds respectively is amplified into 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration:The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby.Powder processed:Root of three-nerved spicebush 9g, camplotheca acuminata 7g are respectively amplified 10 times, it is end together to crush, and crosses 80 mesh sieves, standby.Dispensing:In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.Drying, crushing:The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Granulation:The spice being well mixed is inserted in comminutor and is granulated.Whole grain:The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried:Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.Packaging:First pack, the particle by made by is fitted in polyethylene plastic bag, every bag of 7-8g.Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy).Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine crown prince cancer of the stomach recovering particlesAnd preparation method thereof,It is characterized in that it is by made by the raw material of following weight proportion:
Radix pseudostellariae 25g, root of three-nerved spicebush 9g, Chinese lobelia 20g, fiveleaf akebia fruit 20g,
Phoenix-tail fern 25g, pellet feed 13g, camplotheca acuminata 7g, fruit of glossy privet 15g,
Hairyvein agrimony 9g, sophora flower 10g, celebrating bar are passed the summer in a leisurely way 1g, tomato 50g
This side is the substantially square of one decoction on the one, in practical application, can also increase theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " according to the physique of patient and conditions.
2. the weight proportion of the Hui ethnic group's Chinese medicine crown prince's cancer of the stomach recovering particles according to claim 1, it is characterised in that including following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the root of three-nerved spicebush, camplotheca acuminata, tomato, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10~1.20, it is standby;
(3), powder processed
Camplotheca acuminata 7g, root of three-nerved spicebush 9g are amplified into 10 times, it is end together to crush, cross 80 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir;
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves;
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated;
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed;
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C;
B Packaging
First pack, the pill by made by is fitted in polyethylene plastic bag, every bag of 7-8g;Then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
CN201510749979.7A 2015-11-08 2015-11-08 Hui-nationality traditional Chinese medicine granule with radix pseudostellariae for treating gastric cancer and preparation method thereof Withdrawn CN106668311A (en)

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Application publication date: 20170517

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