CN106668218A - Hui nationality traditional Chinese medicine pseudostellaria heterophylla stomach cancer rehabilitation oral liquid and preparation method thereof - Google Patents

Hui nationality traditional Chinese medicine pseudostellaria heterophylla stomach cancer rehabilitation oral liquid and preparation method thereof Download PDF

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CN106668218A
CN106668218A CN201510749353.6A CN201510749353A CN106668218A CN 106668218 A CN106668218 A CN 106668218A CN 201510749353 A CN201510749353 A CN 201510749353A CN 106668218 A CN106668218 A CN 106668218A
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cancer
oral liquid
medicine
chinese medicine
fructus
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王学礼
王桂芳
马芳
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Yinchuan Shanghetu New Technology Development Co Ltd
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Yinchuan Shanghetu New Technology Development Co Ltd
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Abstract

The invention discloses a formula of a Hui nationality traditional Chinese medicine pseudostellaria heterophylla stomach cancer rehabilitation oral liquid and a preparation method thereof. The oral liquid belongs to a green high-tech Chinese herbal medicine for treating a late gastric cancer, particularly a late gastric cancer which cannot be treated because an operation cannot be performed due to various reasons. The oral liquid belongs to a traditional Chinese medicine oral liquid formed by mixing Chinese herbal medicines, such as pseudostellaria heterophylla, radix salviae miltiorrhizae, camptotheca acuminata decne, fructus ligustri lucidi, ligustrum lucidum, agrimonia pilosa and entada phaseoloide according to a certain ratio, boiling with water, extracting and concentrating, mainly treats a stomach cancer, also treats digestive system cancers, such as a pharyngolaryngeal cancer, an esophagus cancer, a cardiac carcinoma, and a colorectal cancer, and has the characteristics that drug are tasteless, the dosage is moderate, and most of selected drugs are proved, through modern medical pharmacological experiments, to be capable of treating cancers.

Description

Hui ethnic group's Chinese medicine crown prince's gastric cancer recovery oral liquid and preparation method thereof
Technical field
Hui ethnic group's Chinese medicine crown prince gastric cancer recovery oral liquid according to the present invention is a kind of to treat late gastric cancer especially because the green high-tech Chinese herbal medicine of late gastric cancer that cannot be performed the operation of a variety of causes.The invention further relates to the preparation method of the medicine, belongs to Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China's Life Calculation of 74 years old for each person, the probability that Chinese suffer from malignant tumor in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumor, and tumor has become a kind of common disease in China.The cancer patient of China is about more than 700 ten thousand people at present, and is being increased with the speed of more than 100 ten thousand people every year.And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for digestive system cancer patient, wherein patients with gastric cancer accounts for the 41.83% of digestive system cancer patient, almost half.
China is one of incidence gastric cancer rate highest country, and the whole world is annual newly to send out patients with gastric cancer more than 100 ten thousand, and China just account for 42%, and death toll China has accounted for 35%, and the M & M of Chinese gastric cancer is world average level more than 2 times!Inherited genetic factorss among these, immune factor, helicobacter pylori infections factor are all nothing difficult, and most anxious is then environment and dietary factor ...
The early symptom of gastric cancer is not obvious, generally needs time of 2 years or so from incidence gastric cancer to finding tumor, therefore often ignored, once and to standing, most likely reach an advanced stage.
It is operation to control gastric cancer the best way at present, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, 1 year life cycle after most Chemotherapy in Patients less than --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some are detected to be gastric cancer, as a variety of causes cannot be performed the operation,Can only palliative treatment, expect that miracle comes ...
Gastric cancer is disease at present compared with refractory more, but refractory is not represented and cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively Therapeutic Method.The traditional Chinese medical science goes for various each phase cancer with organic conception according to the whole body feature determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of patient.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effects are slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band tumor, and patient is easy to receive and expense is than less expensive.Doctor trained in Western medicine is also considered as Chinese medicine at present can contribute to reducing the toxicity of Radiotherapy chemotherapy, improves cancer related symptoms, improve life quality, extend life cycle as the auxiliary treatment of cancer.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all " compatibility " medicine that function for cancer and effect " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs " are not proved by modern medicine pharmacological evaluation in selected Chinese herbal medicine medical material, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatable poor, high level evidence-based medicine EBM be theoretical and the relative shortage of evidence,Thus the situation for mainly waiting deficiency by rule of thumb for cancer, propose a kind of new dosage and preparation method, there is provided one kind reduces the sickness rate of gastric cancer from the beginning of prevention, start to slow down its tempo from canceration, start to induce the green high-tech Chinese herbal medicine of its atrophy apoptosis from tumor.Specifically, the present invention one be particularly suited for use in treatment cancer before larger gastric ulcer in case its canceration, two is the especially big gastric ulcer that can treat the gastric cancer initial stage, in case which continues to deteriorate, three is to can induce cancerous protuberance atrophy apoptosis into tumor, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to induce self apoptosis of cancerous cell and differentiation to greatest extent, promote cancerous protuberance progressively atrophy.In specific formula, also coordinate determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, according to the origin cause of formation of gastric cancer because dietary factor makes nutrient disequilibrium cause immunologic hypofunction, because Helicobacter pylori infection causes stomach normal cell to be compromised, apoptosis, gastritis, digestive tract ulcer, lymphoproliferative gastric lymphoma " is taken advantage of a weak point " evil poison positive pressure, flee meridians visitor the characteristics of internal organs form product long and cause the basic pathology pathogenesis such as stomach cancer metastasis because evil poison being tied in sick protracted blood stasises and being wrapped blood stasis and is taken advantage of a weak point in opponent's defence, with the method for tonifying speen and tonifying kidney strengthening vital QI to eliminate pathogenic factors reinforcement and elimination in combination, to correct healthy energy interior-deficiency, evil solidifying poison gathers the deficiency with internal organs imbalance of YIN and YANG function reduction, adjust and improve the immunologic function of body.The simultaneously concrete condition according to patient, is respectively adopted different formula, or soothing liver-QI stomach function regulating, sending down the abnormal ascending QI pain relieving, or detoxification and removing stasis, clearing away heat and nourishing YIN, or warming spleen and stomach for dispelling cold, invigorating the spleen and regulating the stomach, or strongly invigorating QI and blood, and strengthening spleen, tonifying kidney ... is reachingReinforcement and elimination in combination, reinforcing and reducing and use, the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of curing gastric cancer, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for patients with gastric cancer, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and finally recovers healthy.Thus also select different treatment methods or several method to share particularly Chinese and western medicine to combine the leeway of Comprehensive Treatment application to consider according to the personal state of an illness, economic situation, personal inclination to patient one, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
Hui ethnic group's Chinese medicine crown prince's gastric cancer recovery oral liquid of the first, described treatment gastric cancer is by made by following weight proportion raw material:
Radix Pseudostellariae 25g, Radix Linderae 9g, Herba Lobeliae Chinensis 20g, Fructus Akebiae 20g,
Herba Pteridis Multifidae 25g, pellet feed 13g, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 7g, Fructus Ligustri Lucidi 15g,
Herba Agrimoniae 9g, Flos Sophorae 20g, celebrating bar are passed the summer in a leisurely way 1g
This side is substantially square for one decoction on the one.In practical application, also the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory can be increased according to the body constitution of patient and conditionsDialectical compatibility " medicine.
In view of with this, basic side's decoction decoction amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.
2nd, by the preparation method that above-mentioned each raw material makes Chinese medicine oral liquid of the present invention it is:
A, extract preparation
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the Radix Linderae, Fructus Lycopersici esculenti, all amplify 10 times, after clean water, be placed in BT-2 rustless steels and extract in kettle, plus after 7-9 times of tap water, be heated to 100 DEG C of constant temperature and extract 1 hour or so, extraction fluid, pressure filtration, filtrate are standby.
B, second extraction:The 5-7 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted or so half an hour, extraction fluid, pressure filtration, filtrate are standby.
C, third time are extracted:The 3-5 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted 20 minutes or so, extraction fluid, pressure filtration, filtrate are standby.
(2), concentration
The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into 900ml, it is standby.
(3), powder processed
Radix Linderae 9g is amplified into 10 times, is crushed as end, cross 80 mesh sieves, loaded in every 0.5g capsule, it is standby.
B, packaging
A. the concentrated solution for preparing is loaded in vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation dose is 8kGy).
B. capsule is loaded in vial or vinyon bottle, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation dose is 8kGy).
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Above-mentioned oral liquid three times a day, 1 bottle every time, on an empty stomach (take half an hour after to drink water in a large number, in order to avoid water down medicinal liquid).Pungent grade to gastrointestinal irritation larger food is not eaten during medication.This medicine is a course for the treatment of in three months, typically takes two to three courses for the treatment of, at most takes four courses for the treatment of.
The effect of each raw material of the present invention:
Radix Pseudostellariae,Mild in medicine property and, sweet in the mouth, play the role of tonifying QI to produce body fluid.Qi-restoratives medicine, Qi-tonifying drug.Effect:Tonification spleen and lung, supplementing QI for promoting the production of body fluid.Control the deficiency of the lungCough, spleen eating less, cardiopalmus, palpitation with a distress feeling, edema quench one's thirst, metal fatigue.For deficiency-weakness of spleen-QI, deficiency of stomach-Yin, lack of appetite body are tired, thirsty dry tongue;Deficiency of the lung cough caused by dryness, dry pharynx expectorant are glued;Deficiency of both vital energy and Yin, palpitation and insomnia.It is usually used in weakness of the spleen and stomach, fatigue and weakness, inappetence, dry cough few expectorant, after being ill body void, night sweat.Experimentation also demonstrates that Radix Pseudostellariae can improve immunologic function, improve cardiac function.
The Radix Linderae,Flavor efficacy:Ye Xin, it is warm in nature.Warming spleen and stomach for dispelling cold, regulating QI to relieve pain.Clinical practice:Closely it is used for digestive tract tumor, such asGastric cancer, intestinal cancer, be additionally operable to bladder cancer etc..Additionally, being additionally operable toTreatmentHeart peratodynia, vomiting and diarrhoeaStomachacheDysmenorrhea, colic, frequent micturition, rheumatalgia, traumatic pain and traumatic hemorrhage.
Herba Lobeliae Chinensis ,For the herb of campanulaceae Herba Lobeliae Sessilifoliae platymiscium Herba Lobeliae Chinensis.Its acrid in the mouth, slight bitter are mild-natured.Main (also known as antabac) containing lobeline, secondly also containing various alkaloids and flavonoid, inulin, sodium succinate, Fumaric acid, P-hydroxybenzoic acid sodium and phenols etc. such as cis-8,10-diphenyllobelidione (lobelanine), cis-8,10-diphenyllobelidiols (lobelanidine).Also containing Saponin, aminoacid etc..Function is heat-clearing and toxic substances removing, inducing diuresis to remove edema.Cure mainly the diseases such as venom, furuncle furuncle and phyma, edema, jaundice.Combined with liver cancer ascites, pulmonary carcinoma;Additionally, Herba Lobeliae Chinensis also appear in the newspapers at aspects such as treatment colorectal cancer, nasopharyngeal carcinoma, esophageal carcinoma, gastric cancer, myeloma, cerebromas.In addition to antitumor action, Herba Lobeliae Chinensis Alkaloid has central excitation to act on, and is important neural cholinergic receptor agonist, and it also has the multiple pharmacological effect such as diuresis, function of gallbladder promoting, antibacterial, antiinflammatory, venom.
Fructus Akebiae,ForLardizabalaceaePlantCaulis Akebiae threeleaf akebiaOrCaulis AkebiaeDry mature fruit.Sweet in the mouth, cold in nature, function isDepressed liver-energy dispersing and QI regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.Cure mainlyStomachache due to hyperactive liver-QI attacking the stomachGastric heatFood is slow-witted, excessive thirst,DysenteryLumbagoHypochondriac pain, hernia etc..The less single of Fructus Akebiae is used for kinds of tumors with his medicine phases 5 more, and is had preferable curative effect more with controlling in tumor.
Pellet feeds,Nature and flavorEffect:Bitter in the mouth, cold nature.Stasis-dispelling and pain-killing, promoting blood flow to regulate menstruation, nourishing heart relieving restlessness.It is clinicalUsing:Suitable for the digestive tract tumor accumulate in stagnation of QI-blood, pyretic toxicity, the osteosarcoma or bone metastaes of stasis meridians are additionally operable to.Additionally, being usually used inTreatment menoxenia, amenorrhea,Ectopic pregnancy, hepatosplenomegaly, angina pectoriss, dysphoria and insomnia, sore swollen toxin.
Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae),Nature and flavorEffect:It is bitter in the mouth, puckery, it is cold in nature, it is poisonous.Anticancer, eliminating stagnation, heat clearing away parasite killing.
It is clinicalUsing:Suitable for kinds of tumors, such as the esophageal carcinoma,Gastric cancer, rectal cancer, hepatocarcinoma, bladder cancer, adenocarcinoma ovarieses, chronic myelocytic leukemia, acute lymphoblastic leukemia, lymphosarcoma etc..
Fructus Ligustri Lucidi,Effect:Tonifying liver kidney yin, crow must improving eyesight.Drug effect:For the hepatic and renal YIN deficiency, Light-headedness, seminal emission tinnitus, soreness of the waist and knees, poor vision, visual deterioration, poor vision, fever due to yin deficiency, early whitening of beard and hair, tumor, soreness of waist tinnitus and fever due to yin deficiency etc. are controlled.This product energy tonifying liver kidney yin, but the efficacy of a drug is gentle, must slowly take effect, treatmentCoronary heart disease, hyperlipemia, hypertension, chronic hepatitiss etc..
Herba Agrimoniae,Nature and flavor are bitter, puckery, put down.GUIXIN, Liver Channel.Indication:Astringing to arrest bleeding, preventing the attack (or recurrence) of malaria, dysentery relieving, removing toxic substances.For hemoptysis, spit blood, metrostaxiss, malaria, dysentery, de-power internal lesion caused by overexertion, carbuncle sore tumefacting virus, pudendal pruritus leukorrhagia.Early in the Ming Dynasty, China physician Jiang Yi just willHerba AgrimoniaeFor treatingEsophageal carcinomaWithGastric cancer.He is write in curing:" rolling pharynx every expectorant, flat regurgitation of food from the stomach it is dirty ", swallow every regurgitation of food from the stomach be ancients to describe the disease of esophageal carcinoma and gastric cancer, " always doctor's faciation fear, think incurable disease." " remaining to obtain this agent, ten throw nine imitates ".CancerAfter patient takes Herba Agrimoniae, such as " foxtail millet of famine, the fur coat in midwinter ".Modern medicine study finds that Herba Agrimoniae extracting solution at least contains 12 kinds of compositions, and its major part is in cancer resistance.
Flos Sophorae, nature and flavorHardship, is slightly cold.Return liver, large intestine channel.Effect:Cooling blood for hemostasis, liver heat removing and eyesight improving.It is additionally operable to the dizziness and headache of flaming up of liver-fire(Modern study it have certain hypotensive activity, especially cold fragrant glycosides, is called rutin, can reduce the permeability of blood capillary, and the fragility of reduction blood vessel has good protective effect, is less prone to cerebrovas-cularaccident bleeding to blood vessel), fundus oculi disease all can use.Effect:1. cooling blood for hemostasis, goes out blood disorder for heat in blood.Such as haematemesis, epistaxis, have blood in stool, hemorrhoidal bleeding etc..The cold and bitter drop of this product, Return liver, large intestine channel are kind to let out clearly large intestine burning hot and cooling blood for hemostasis, therefore to treat bottom bleeding to be good at, and such as hemorrhoidal bleeding, have blood in stool.Treating hematochezia, often matches somebody with somebodyHerba SchizonepetaeCacumen PlatycladiEquivalent is used.Haematemesis, epistaxis are controlled, is then often matched somebody with somebodyRhizoma ImperataeEquivalent is used.2. clearing away liver-fire, for the headache feeling of fullness in the head of flaming up of liver-fire, conjunctival congestion, dizziness etc..Modern clinic is also commonly used for hypertension and belongs to the partially prosperous person of liver-fire, has the work(of liver heat removing and eyesight improving blood pressure lowering.This product contains rutin, Flos Sophorae A prime, B prime, C prime, tannin.The permeability and fragility of blood capillary can be reduced, shortens the bleeding time, strengthen the resistance of blood capillary.There is blood pressure lowering, prevent and treat arteriosclerosis, expand coronary vasodilator, improve the effect such as myocardial circulation.This product has antiinflammatory, antibacterial, antiviral, the permeability and fragility that can reduce blood capillary, shortens the bleeding time;Strengthen the resistance of blood capillary;Lowering blood pressure and blood fat, arteriosclerosis are prevented and treated, have expansion coronary vasodilator, improve the effect such as myocardial circulation.The cold and cool and bitter drop of this product, it is kind to let out clearly liver, stomach, the heat of large intestine and cooling blood for hemostasis, it is good at especially and treats hemorrhoidal bleeding, has blood in stool.
Celebrating bar is passed the summer in a leisurely way,Nature and flavorEffect:Gan Liang, heat-clearing and toxic substances removing.It is clinicalUsing:Anticancer, parasite killing, the spiral shell that goes out, emetic rush down.
Fructus Lycopersici esculenti,Fructus Lycopersici esculenti has fat-reducing Weight reducing , allaying tiredness, appetite stimulator, raising to the digestion of protein, reduce flatulence food stagnation the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, Fructus Lycopersici esculenti always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the Fructus Lycopersici esculenti in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction convert), anticancer propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have the cytokines secretion of anti-cancer, antitumaous effect, such as interleukin-II, dissolution of the activated lymphocyte to cancerous cell;The lymphocyte being activated can discharge cytokines such as tumor necrosis factor etc. again, have lethal effect to tumor cell.3rd, lycopene has stronger Antioxidation Effect.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene etc.) is effectively removing free radical, so as to play whole body health-care effect, wherein playing an important role in being just included in protective effect on cancer risk.
The effect of the present invention:
Cure mainly:Gastric cancer, especially because a variety of causes cannot carry out the late gastric cancer of Surgery for Gastric Carcinoma, with very low cost, fundamentally improves physical function, and control tumor continues to overgrow and makes which that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as laryngocarcinoma, the esophageal carcinoma, cardiac cancer, pylorus cancer, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug are more, and dosage is moderate, do not waste.
2nd, selected flavour of a drug are mostly that proved by modern medicine pharmacological evaluation can be for cancer, and existing proved recipe for cancer, then always there are medicines more than half to be all not proved function for cancer and effect by modern medicine pharmacological evaluation in folk prescription.
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, being as a result that " dragon " is more bad on the contrary harnesses the river.
4th, as much as possible " neutralization ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus made to be suffered within the cycle of whole medication less, be pulled the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, add a bit " stopping leak ", the medicine of " pathogenic fire reducing " dialectically temporarily and specifically solve.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequencess.
Specific embodiment:Radix Pseudostellariae 25g, Herba Lobeliae Chinensis 20g, Fructus Akebiae 20g, Herba Pteridis Multifidae 25g, pellet 13g, Fructus Ligustri Lucidi 15g, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 7g, Herba Agrimoniae 9g, Flos Sophorae 10g, the celebrating bar 1g that passes the summer in a leisurely way that feeds respectively is amplified into 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate are standby.Extract for second:The 5-7 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted or so half an hour, extraction fluid, pressure filtration, filtrate are standby.Third time is extracted:The 3-5 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted 20 minutes or so, extraction fluid, pressure filtration, filtrate are standby.Concentration:The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into 900ml, it is standby.Powder processed:Radix Linderae 9g is amplified into 10 times, it is end together to crush, and crosses 80 mesh sieves, loaded in every 0.5g capsule, it is standby.Packaging:A. the concentrated solution for preparing is loaded in vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation dose is 8kGy).B. capsule is loaded in vial or vinyon bottle, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation dose is 8kGy).Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine " crown prince's gastric cancer recovery oral liquid "And preparation method thereof,It is characterized in that it is by made by the raw material of following weight proportion:
Radix Pseudostellariae 25g, Radix Linderae 9g, Herba Lobeliae Chinensis 20g, Fructus Akebiae 20g,
Herba Pteridis Multifidae 25g, pellet feed 13g, Fructus seu radix camptothecae acuminatae (Fructus Camptothecae Acuminatae) 7g, Fructus Ligustri Lucidi 15g,
Herba Agrimoniae 9g, Flos Sophorae 10g, celebrating bar are passed the summer in a leisurely way 1g
This side is the substantially square of one decoction on the one, in practical application, can also increase theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " according to the body constitution of patient and conditions.
2. the weight proportion of Hui ethnic group's Chinese medicine " crown prince's gastric cancer recovery oral liquid " according to claim 1, it is characterised in that including following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to the Radix Linderae, Fructus Lycopersici esculenti, all amplify 10 times, after clean water, be placed in BT-2 rustless steels and extract in kettle, plus after 7-9 times of tap water, be heated to 100 DEG C of constant temperature and extract 1 hour or so, extraction fluid, pressure filtration, filtrate are standby;
B, second extraction:The 5-7 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted or so half an hour, extraction fluid, pressure filtration, filtrate are standby;
C, third time are extracted:The 3-5 times of tap water measured add in kettle toward being extracted, 100 DEG C of constant temperature is heated to and is extracted 20 minutes or so, extraction fluid, pressure filtration, filtrate are standby;
(2), concentration
The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into 900ml, it is standby;
(3), powder processed
Radix Linderae 9g is amplified into 10 times, is crushed as end, cross 80 mesh sieves, loaded in every 0.5g capsule, it is standby;
B, packaging
A. the concentrated solution for preparing is loaded in vial or vinyon bottle, every bottle of 30ml, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation dose is 8kGy);
B. capsule is loaded in vial or vinyon bottle, mounted box, vanning, sterilizing (adopt 60Co irradiation, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
CN201510749353.6A 2015-11-08 2015-11-08 Hui nationality traditional Chinese medicine pseudostellaria heterophylla stomach cancer rehabilitation oral liquid and preparation method thereof Withdrawn CN106668218A (en)

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