CN106668422A - Hui nationality traditional Chinese medicine particles for treating esophageal cancer and preparation method thereof - Google Patents

Abstract

The invention discloses a formula of Hui nationality traditional Chinese medicine particles for treating esophageal cancer and a preparation method of the Hui nationality traditional Chinese medicine particles. The Hui nationality traditional Chinese medicine particles are eco-friendly high-tech traditional Chinese medicines for treating esophageal cancer and are prepared from traditional Chinese medicines such as radix sophorae tonkinensis, root-bark of Araiia chinensis L., smoked plum, semen cuscutae and the like according to a certain proportion through material blending, water decoction, extraction, concentration and granulation. The Hui nationality traditional Chinese medicine particles are mainly used for treating esophageal cancer and also can treat digestive system cancers such as pharyngolaryngeal cancer, gastric cancer and colorectal cancer. The Hui nationality traditional Chinese medicine particles have a moderate taste and a moderate dose. The selected traditional Chinese medicines are proved to be able to treat cancers by the modern medical pharmacology experiments, have a very low price, can prevent and treat cell cancerization and can restore health.

Description

Hui ethnic group's Chinese medicine oesophagus holds back cancer particle and preparation method thereof

Technical field

It is a kind of green high-tech Chinese herbal medicine of the prevention and treatment cancer of the esophagus that Hui ethnic group's Chinese medicine oesophagus according to the present invention holds back cancer particle.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.

Background technology

According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, Chinese all one's life suffer from malignant tumour probability be 22%, average minute clock has 6 people to be diagnosed as malignant tumour, and tumour has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.And the whole world

According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patient with esophageal carcinoma accounts for the 29.7% of Alimentary System patient, almost half.

Cancer of the esophagusDisease locus are typically organized in epithelium of esophagus, and it is exactly swallowing and digestive function for patient that it directly affects, and health is slowly etched with regard to this.The pathogenic factor of cancer of the esophagus mainly has three, and one is malnutritive, though that is, now the living standard of people improves, due to the change of diet hobby and mode, will also result in malnutritive and trace element shortage；Two is that diet is lack of standardization, and in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase, and these materials are easily-synthesized carcinogen nitrosamine in stomach；Three is esophageal injury and disease induction, and esophageal injury and some esophagel diseases are likely to become the inducement for causing cancer of the esophagus, and long-term chronic inflammation, ulcer, or chronic stimulation, and then esophageal epithelial proliferation are caused because of being detained in oesophagus, finally result in canceration.Although cancer of the esophagus does not possess infectiousness, the destruction to human body is but not allow to look down upon.

Though the early symptom of the cancer of the esophagus is more substantially, generally always flu etc is mistakenly considered by people, therefore often ignored, but do not know that the speed that cancer of the esophagus slowly deteriorates is very fast, once and feel increasingly apparent to be difficult to swallow, most likely deteriorated as cancer.Afterwards may be by operation to the process of cancerization Regional resection, to reduce the death rate of cancer of the esophagus.

At present treatment cancer of the esophagus the best way is operation, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, the life cycle after most Chemotherapy in Patients was with regard to 1 year or so --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some perform the operation, held due to a variety of causes and can't stand chemotherapy,Can only palliative treatment, expect that miracle comes ...

The cancer of the esophagus is at present more refractory disease more as cancer of the stomach, all, but refractory representative cannot be controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science, according to the whole body feature diagnosis and treatment of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " diagnosis and treatment based on an overall analysis of the illness and the patient's condition " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medicinal material, inventors believe that very improper；And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.

The content of the invention

The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatable poor, high level evidence-based medicine EBM be theoretical and the relative shortage of evidence,Thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided one kind reduces the incidence of disease of the cancer of the esophagus from the beginning of prevention, start to slow down its tempo from canceration, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one is particularly suited for use in esophageal ulcer before treatment cancer in case its canceration, two is can to treat cancer just ulcer, in case it continues to deteriorate, three is inducible into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In specific formula, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, induced because of esophageal injury, disease according to the origin cause of formation of cancer of the esophagus, dietary preferences nutrient imbalance causes immunologic hypofunction, cause normal cell to be compromised because of Helicobacter pylori infection, apoptosis, digestive tract ulcer, canceration " taking advantage of a weak point ", because " weakened body resistance poison poly- ", " empty in healthy tendency " and the characteristics of causes the basic pathology interpretation of the cause, onset and process of an illness such as metastases, utilization or strengthening vital QI to eliminate pathogenic factors, orTonification and purgation in combination, or regulating qi to disperse stagnation, or the strongly fragrant resolving sputum of solution, or it is clearing heat and detoxicating, or reinforcing and reducing methods and the method used, it is empty in healthy tendency to correct, poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjust and improve the immunologic function of body, to reach the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of carninomatosis treatment, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for esophageal cancer patients, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, finally recover healthy.Thus also to patient one select different treatment methods or several method to share particularly traditional Chinese and western medicine to combine the leeway of complex treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.

Technical scheme proposed by the invention is：

Hui ethnic group's Chinese medicine oesophagus of the first, the described prevention and treatment cancer of the esophagus holds back cancer particle and preparation method thereof, is by made by following weight proportion raw material：

Subprostrate sophora 30g, neglect wood 20g, airpotato yam 7g, dark plum 9g,

Seed of Chinese dodder 10g, mushroom 9g, pellet feed 10g, bark of tree of heaven 7g,

Chinese yam rhizome 20g, Radix Glycyrrhizae 7g, honey 30g,

This side is substantially square for one decoction on the one.In practical application, also the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory can be increased according to the physique of patient and conditions“Dialectical compatibility " medicine.

In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.

2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal granule of the present invention：

A, extract preparation

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to dark plum, bark of tree of heaven, Radix Glycyrrhizae, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.

B, second extraction：Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.

C, third time are extracted：Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.

（2）, concentration

The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.

（3）, powder processed

Dark plum 9g, bark of tree of heaven 7g, Radix Glycyrrhizae 7g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.

（4）, dispensing

In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.

(5) drying, crushing

The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.

(6) granulate

The spice being well mixed is inserted in comminutor and is granulated.

(7) whole grain

The particle for making is carried out into whole grain, 35 mesh sieves are crossed.

(8) it is dried

Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.

B, packaging

First the particle for making is fitted in vinyon pouch, every bag of 8g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.

, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.

Routine instructions of taking of the invention：Three times a day, 1 bag of 8g every time, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.

This medicine does medicine efficacy enhancing ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is：Take from so well-done little tomato（50 grams or so）Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, pours into be decocted in pot by the tomato of chopping when chopped spring onion blows out fragrance and fries 1-2 minutes, then infuses to be got away into suitable quantity of water and take the dish out of the pot.

The effect of each raw material of the present invention：

Subprostrate sophora,ForLegume root of subprostrate sophoraRoot.Bitter cold in nature.Effect is to relieve inflammation or internal heat, detoxifying, subsiding a swelling, pain relieving.Cure mainly：Laryngalgia, sore-throat,Larynx numbness,Swelling and aching of gum,Breathe heavily fullHeat is coughed,Jaundice, diarrhea, heat is swollen,Mange, snakeworm dog bite.Its is rightThe cancer of the esophagus、Nasopharyngeal carcinoma, cervical carcinoma,Carcinoma of urinary bladder, leukaemia have inhibitory action.Composition pharmacology：Containing TA about 0.93%, whereinMatrine(Matrine) 0.52%,Oxymatrine(Oxymatrine) 0.35%, Yi JihanD-maackianin-β-D-glucoside(Sophoraponicin)、Red sandalwoodPlain (Pterorepine),Screw oil expeller axleGrass roots glucoside (TrifolirhiZin),Albizzia kalkoraPlain (Maackian), sophoradin (Sophra) etc..DNA and RNA synthesis of the subprostrate sophora to tumour cell has obvious inhibitory action, so as to block the propagation of tumour cell, lymphocyte transformation can be promoted, excite or strengthen the CDCC of lymphocyte, T cell ratio is improved, strengthens or adjust macrophage phagocytic function, moreover it is possible to adjust endocrine, strengthen adrenocortical function, thus affect the occurrence and development of tumour.

It is suddenly wooden,Containing araloside suddenly, protocatechuic acid, choline and volatile oil etc..The property of medicine is sweet, pungent, puts down.Return liver, courage, stomach, large intestine, lung, kidney channel.Drug effect：Internal heat anticance, anti-inflammatory detumescence, clearing damp Li Shui.Medicinal (1) internal heat anticance, for carcinoma product poison：Cholangiocarcinoma, cancer of the stomach, the carcinoma of the rectum, lung cancer etc.；(2) anti-inflammatory detumescence, swells and ache for inflammation：Cystitis；(3) clearing damp profit fire, for edema caused by wind-dampness：Nephritic dropsy.Nature and flavorEffect：It is bitter, cold in nature.Heat-clearing and damp-drying drug, purging intense heat and detonicating.It is clinicalUsing：Suitable for various arsine knurls, such as liver, courage tumour, tongue cancer, lip cancer, the cancer of the esophagus,Cancer of the stomach, carcinoma of urinary bladder etc..

Airpotato yam,Nature and flavorEffect：Bitter, it is mild-natured, it is slightly poisonous.Removing toxicity for detumescence, reducing phlegm and resolving masses, cooling blood and hemostasis.It is clinicalUsing：Suitable for kinds of tumors, such as the cancer of the esophagus,Cancer of the stomach, nasopharyngeal carcinoma, thyroid tumors, lymphosarcoma, lung cancer, sonCervical carcinoma, rhabdomyosarcoma, intestinal cancer and cancer of pancreas etc..Additionally, applying also for big endemicgoiter, hyperthyroidism, tracheitis, pertussis, hemoptysis, haematemesis, scrofula, sore tumour, venomous snake bite etc..

Dark plum,Nature and flavorEffect：Sour-puckery flavor, it is warm in nature.Astringe the lung puckery intestines, promote the production of body fluid to quench thirst.CanTreatmentCancerous swelling.Be clinically used for treat carcinoma of penis,Cervical carcinoma, colon and rectum carcinoma, the cancer of the esophagus,Cancer of the stomachDeng.Additionally, being additionally operable to treat chronic cough of deficiency lung, dry polydipsia, ascarid of biliary tract, cholecystitis, bacillary dysentery, chronicDiarrhoea, Lu pass through many, psoriasis.External curing ulcer does not close up long, corn etc..

The seed of Chinese dodder,It is warm in nature；It is sweet；Return liver, spleen, kidney channel.Effect and nourishing liver and kidney, antiabortive, the improving eyesight of effect, antidiarrheal.For：Impotence and seminal emission, dripping urination, enuresis frequent micturition, medicine knees soreness, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, fetal irritability, spleen kidney deficiency is rushed down；Externally treating leucoderma, the ability with certain inhibition cancer cell can reduce the incidence of canceration.

Mushroom,Mushroom is cold in nature, mildly bitter flavor, favourable liver benefit stomachEffect.Mushroom not only has the peculiar flavour of delicate fragrance, and containing abundant composition calcium, phosphorus, the iron beneficial to human body, also containing polysaccharide, vitamin B1, vitamin B2, vitamin C etc..Containing the composition such as several amino acids, acetamide, choline, adenine in the infusion of dried thin mushroom, the cholesterol in blood can be reduced, atherosclerosis, to prevent and treat cerebral hemorrhage, heart disease, obesity andDiabetesIt is all effective.In recent years, American scientist find in mushroom containing it is a kind of " β-GrapeGlycosidase ", test proves that this material plays the role of significantly to strengthen body against cancer, therefore, people call mushroom " anticancer new recruit ".Mushroom is also resistant toFluVirus, because containing a kind of derivant of interferon in mushroom, can induce the generation of internal interferon, the synthesis of viral interference protein so as to irreproducible, so that human body produces immunization.Ancient Times in China scholar early has found perfume (or spice)Mushroom based foodIt is improved the effect of function of brain cell.Such as《Legendary god of farming's book on Chinese herbal medicine》In just have take bait mushroom can be with " increasing wisdom ", the record of " intelligence development is happy ".Modern medicine thinks that the increasing intelligence effect of mushroom is, containing abundant arginine and lysine, often to eat, and can be healthy and strong intelligence development.

Pellet feeds,Nature and flavorEffect：Bitter, cold nature.Stasis-dispelling and pain-killing, promoting blood circulation for regulating menstruation, nourishing heart relieving restlessness.It is clinicalUsing：Suitable for the tumor in digestive tract accumulate in stagnation of QI-blood, heat toxin, the osteosarcoma or bone metastaes of stasis channels and collaterals are additionally operable to.Additionally, being usually used inTreatment irregular menstruation, Amenorrhea,Ectopic pregnancy, hepatosplenomegaly, angina pectoris, dysphoria and insomnia, sore swollen toxin.

Bark of tree of heaven,Nature and flavorEffect：Root skin bitter, puckery, cold in nature, eliminating dampness heat-clearing, antidiarrheal, hemostasis.Fruit bitter, cool in nature, reducing fever and causing diuresis, pain relieving, hemostasis.It is clinicalUsing：Suitable for colon and rectum carcinoma,Cervical carcinomaDeng.Additionally, CORTEX AILANTHI apply also for chronic dysentery, enteritis, have blood in stool, pass out semen, leukorrhea, featureUterusBleeding.Fruit applies also for having a stomachache, has blood in stool, hematuria;Trichomonas vaginalis is controlled in external application.

Chinese yam rhizome,Meridian distribution of property and flavor:It is sweet, it is mild-natured.Returns spleen, lung,Kidney channel.Effect:Tonifying spleen nourishing the stomach,Promote the production of body fluidBeneficial lung,Kidney tonifyingPuckery essence, it is clearing heat and detoxicating.Cure mainly：It is insufficiency of the spleenDeficiency of food, endless diarrhea, the deficiency syndrome of the lung breath with cough,Emission due to the kidney deficiency, under band,Frequent micturition, abnormal heatQuench one's thirst.Among the people, Chinese yam is on record excellent tonic product.It contain protein,Carbohydrate, vitamin,Fat、Choline、AmylaseDeng composition, also containing human bodies such as iodine, calcium, iron, phosphorusIt is indispensable'sInorganic saltsAnd trace element.The traditional Chinese medical science thinks, Chinese yam " qi-restoratives in main wound, except fever and chills perverse trend, tonifying middle-Jiao and Qi power, long muscle, long term usage normal hearing and eyesight ".Many classic medicine writings have all made very high evaluation to Chinese yam.Modern medicine study thinks that Chinese yam has following effect:1. Chinese medicine for lowering blood pressure Liuwei Dihuang Wan, Rehmanniae Bolus of Eight Ingredients, 'Guishao Dihuang ball etc., are all the famous prescriptions for having Chinese yam to be made into, and are applied not only to treat kidney deficiency illness, are additionally operable to treat the illnesss such as hypertension, diabetes, asthma, neurasthenia and pain in the back.2. anti-aging modern science proves that Chinese yam significantly reduces can the enzymatic activity of acceleration organism aging.Rehmanniae Bolus of Eight Ingredients containing Chinese yam, cures mainly sweating continuously due to deficiency after delivery.Protect the clear drop soup of unit, protect the cold drop soup of unit, haematemesis and nosebleed can be controlled;It is cold to drench soup and cream pouring soup, pouring worm can be controlled.Chinese yam can also control pulmonary tuberculosis, typhoid fever and gynaecological disease etc., and this is all conducive to promoting longevity.3. antitumor action Chinese yam stem tuber is rich in polysaccharide, can stimulate and adjust human immune system.Therefore the health medicine for often making to strengthen immunocompetence is used.Chinese yam polysaccharide has antagonism to Cellular immunity suppression caused by endoxan institute, and repressed cellular immune function can be made partly or entirely to recover normal.Chinese yam can also strengthen the phagocytosis of leucocyte.Such as, Liuwei Dihuang Wan can treat the illnesss such as chronic nephritis, hypertension, diabetes, neurasthenia.The Pill of Anemarrhena, Phellodendrom and Rehmannia can treat the fire excess from yin deficiency disease such as ankylosing spondylitis and gynaecology's threatened abortion, pruritus vulvae, Amenorrhea.'Guishao Dihuang ball can treat otalgia tinnitus, deficiency of Yin spontaneous perspiration etc..4. the effect that allantoin contained in skin disease Chinese yam has analgesia can be controlled, epithelial growth, anti-inflammatory and antibacterial can be promoted, be usually used in treating rhagadia manus et pedis, ichthyosis and various angling dermatoses.Modern science is analyzed, and the maximum feature of Chinese yam is containing substantial amounts of mucin.Mucin is a kind ofPolysaccharideProteinMixture, there is special health-care effect to human body, can prevent the sedimentation of fat on angiocarpy, blood vessel elasticity is kept, prevent atherosclerotic from occurring to early;Subcutaneous fat deposits can be reduced;The atrophy of connective tissue can be prevented, prevents the generation of the collagen diseases such as rheumatoid arthritis, chorionitis.Many nourishing prescriptions, such asLiuwei Dihuang Wan、Qiju Dihuang Wan、Guipi decoction、The ginseng Siberian cocklebur bighead atractylodes rhizomeDissipate and wait Chinese medicine all to contain Chinese yam.

Radix Glycyrrhizae,Root and root system master contain triterpenoid saponin, wherein main one kind is commonly called as glycyrrhizin, and the 4',7-Dihydroxyflavanone of chlorins compound containing flavones, liquiritin etc., the also Radix Glycyrrhizae of compound containing Coumarins coumarin, glycyol etc., separately containing compounds such as alkaloid, Radix Glycyrrhizae glucan GBW.Sweet, mild-natured, returns spleen, stomach, the heart, lung channel, invigorating middle warmer and replenishing QI, relieving spasm to stop pain moistens the lung and relieve the cough, purging intense heat and detonicating, coordinating the drug actions of a prescription.Burnout deficiency of food is cured mainly, the thin face of flesh is yellow, palpitation, suffer from abdominal pain loose stool, four limbs contraction, hysteria, cough and asthma, abscess of throat, ulcerative carbuncle pyogenic infections, infant fetal toxin and medicine, food poisoning.Radix Glycyrrhizae has removing toxic substances antibacterial action, anti-AIDS toxic action, licorice polysaccharide has obvious inhibiting effect to vesicular stomatitis virus, adenovirus II type, herpes simplex virus I type and vaccinia virus in vitro, not only can directly inactivate this several virus, and also have effect to intracellular virus, additionally, Radix Glycyrrhizae also has Antitussive and Expectorant Effect, with anti-inflammatory, affect digestive system, immune system and cardiovascular system, the effect such as antitumor and anti-mutation, corticotropin sample, anti-oxidant.The acute and chronic viral hepatitis of clinical treatment, treatment diabetes, treatment gastric and duodenal ulcer etc..The present invention is to the concocting method of Radix Glycyrrhizae：Extracting liquorice, except removing LU and impurity, size bar is separate, be dipped to 3 four one-tenth it is saturating when, pick up and soften, cut sheet, be dried.

Honey,Effect of honey and effect：1. the good merchantable brand of cardiovascular patient,HoneyThe composition of blood can be improved, promote heart and brain and vascular function, therefore Jing informal dresses very good for cardiovascular patient；2. protect liver, honey to have protective effect to liver, liver cell regeneration can be promoted, the formation to fatty liver has certain inhibitory action；3. build up resistance, edible honey can regain one's strength of body rapidly, dispelling fatigue builds up one's resistance to disease；4. sterilized, honey also has sterilized effect, Jing often to eat honey, not only without prejudice to tooth, moreover it is possible to play a part of sterilizing in oral cavity, honey can treat the skin damage of moderate, particularly scald, when honey is regarded into skin wound dressing, bacterium cannot grow；5. promote sleep, the people of the insomnia oral 1 soupspoon honey (in 1 glass of warm water of addition) before sleep daily to help fall asleep as early as possible；6. promote gastrointestinal peristalsis, honey to have adjustment effect to gastrointestinal function, gastric acid secretion can be made normal.Zoopery confirms that honey plays the role of to strengthen enterocinesia, can significantly shorten defecation time.

Tomato,Tomato has fat-reducing Weight reducing , dispelling fatigue, improve a poor appetite, improve the digestion to protein, reduce gasteremphraxis dyspepsia the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, tomato always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the tomato in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction conversion), inhibition cancer cell propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have the cytokine secretion of anti-cancer, antitumaous effect, such as interleukins-II, dissolution of the activated lymphocyte to cancer cell；The lymphocyte being activated can discharge cytokine such as TNF etc. again, have lethal effect to tumour cell.3rd, lycopene has stronger It is anti-oxidant Effect.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein be just included in protective effect on cancer risk playing an important role.

The effect of the present invention：

Cure mainly：The cancer of the esophagus, particularly the early stage cancer of the esophagus, with very low cost, fundamentally improve physical function, and control tumour continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.

It is simultaneous to control：The cancer in digestive system such as throat cancer, cardiac cancer, pylorus cancer, cancer of the stomach, colorectal cancer.

Our the characteristics of is：

1st, flavour of a drug are more, and dosage is moderate, do not waste.

2nd, selected flavour of a drug are all to be proved that for cancer the cancer of the esophagus particularly can be treated by modern medicine pharmacological evaluation.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by modern medicine pharmacological evaluation proved function for cancer and effect.Really it is that the traditional Chinese medical science is seen a doctor by rule of thumb, folk prescription is cured the disease by risk！

3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, be as a result that " dragon " does not harness the river on the contrary more.

4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequences.

Specific embodiment：By subprostrate sophora 30g, suddenly wood 20g, airpotato yam 7g, seed of Chinese dodder 10g, mushroom 9g, pellet feed, and 10g, Chinese yam rhizome 20g are each to amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second：Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted：Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration：The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.Powder processed：Dark plum 9g, bark of tree of heaven 7g, Radix Glycyrrhizae 7g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.Dispensing：In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and 30g honey and is sufficiently mixed, stir.Drying, crushing：The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Granulation：The spice being well mixed is inserted in comminutor and is granulated.Whole grain：The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried：Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.Packaging：First the particle for making is fitted in vinyon pouch, every bag of 8g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine oesophagus holds back cancer particle and preparation method thereof, it is characterised in that it is by made by the raw material of following weight proportion：

Subprostrate sophora 30g, neglect wood 20g, airpotato yam 7g, dark plum 9g,

Seed of Chinese dodder 10g, mushroom 9g, pellet feed 10g, bark of tree of heaven 7g,

Chinese yam rhizome 20g, Radix Glycyrrhizae 7g, honey 30g,

This side is the substantially square of one decoction on the one, in practical application, can also increase the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory according to the physique of patient and conditions“Dialectical compatibility " medicine.

2. the Hui ethnic group's Chinese medicine oesophagus according to claim 1 holds back the weight proportion of cancer particle, it is characterised in that including following preparation processes：

A, extract preparation

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to dark plum, bark of tree of heaven, Radix Glycyrrhizae, all amplify 10 times, after clean water, it is placed in BT-2 stainless steels to extract in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby；

B, second extraction：Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby；

C, third time are extracted：Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby；

（2）, concentration

The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby；

（3）, powder processed

Dark plum 9g, bark of tree of heaven 7g, Radix Glycyrrhizae 7g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby；

（4）, dispensing

In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir；

(5) drying, crushing

The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves；

(6) granulate

The spice being well mixed is inserted in comminutor and is granulated；

(7) whole grain

The particle for making is carried out into whole grain, 35 mesh sieves are crossed；

(8) it is dried

Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C；

B, packaging

First the pill for making is fitted in vinyon pouch, every bag of 8g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）；

C, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.