CN106668520A - Hui nationality traditional Chinese medicine radix sophorae tonkinensis, lentinula edodes and pseudobulbus cremastrae seu pleiones esophagus cancer restraining tablet and preparation method thereof - Google Patents

Hui nationality traditional Chinese medicine radix sophorae tonkinensis, lentinula edodes and pseudobulbus cremastrae seu pleiones esophagus cancer restraining tablet and preparation method thereof Download PDF

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CN106668520A
CN106668520A CN201510749263.7A CN201510749263A CN106668520A CN 106668520 A CN106668520 A CN 106668520A CN 201510749263 A CN201510749263 A CN 201510749263A CN 106668520 A CN106668520 A CN 106668520A
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cancer
tablet
medicine
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chinese medicine
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王学礼
王桂芳
马芳
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Yinchuan Shanghetu New Technology Development Co Ltd
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Yinchuan Shanghetu New Technology Development Co Ltd
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Abstract

The invention discloses a formula of a Hui nationality traditional Chinese medicine radix sophorae tonkinensis, lentinula edodes and pseudobulbus cremastrae seu pleiones esophagus cancer restraining tablet and a preparation method thereof. The tablet belongs to a green high-tech Chinese herbal medicine for treating an esophagus cancer, belongs to a traditional Chinese medicine tablet formed by mixing Chinese herbal medicines, such as radix sophorae tonkinensis, lentinus edodes, pseudobulbus cremastrae seu pleiones and sal ammoniacus according to a certain ratio, adding water, boiling, extracting, concentrating and tabletting, mainly treats the esophagus cancer, also treats digestive system cancers, such as a pharyngolaryngeal cancer, sa tomach cancer and a colorectal cancer, and has the characteristics that drug tastes and doses are moderate, selected drugs are proved, through modern medical pharmacological experiments, to be capable of treating cancers, and through adoption of the tablet, the physical function is fundamentally improved at low cost, cell canceration is prevented and controlled, and health is regained.

Description

Hui ethnic group's Chinese medicine root eats oesophagus and holds back cancer piece and preparation method thereof
Technical field
It is a kind of green high-tech of the prevention and treatment cancer of the esophagus that Hui ethnic group's Chinese medicine root according to the present invention eat oesophagus to hold back cancer piece Chinese herbal medicine.The invention further relates to the preparation method of the medicine, belongs to traditional Chinese medicine class.
Background technology
According to《China's tumour registration annual report in 2014》Data display, according to China for each person 74 years old life-span calculate, China The probability that people suffers from malignant tumour in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumour, tumour China into For a kind of common disease.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase. And the whole world
According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for Alimentary System patient, wherein patient with esophageal carcinoma Account for the 29.7% of Alimentary System patient, almost half.
Cancer of the esophagusDisease locus typically organize in epithelium of esophagus, its directly impact be exactly that patient swallows and digest work( Can, health is slowly etched with regard to this.The pathogenic factor of cancer of the esophagus mainly has three, and one is malnutritive, though i.e. people now Living standard improve, but due to the change of diet hobby and mode, will also result in malnutritive and trace element lacking It is weary;Two is that diet is lack of standardization, and in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase, These materials are easily-synthesized carcinogen nitrosamine in stomach;Three be esophageal injury and disease induction, esophageal injury and some food Pipe disease is likely to become the inducement for causing cancer of the esophagus, is detained and cause long-term chronic inflammation, ulcer because of in oesophagus, or slowly Sexual stimulus, and then esophageal epithelial proliferation, finally result in canceration.Although cancer of the esophagus does not possess infectiousness, the destruction to human body But it is not allow to look down upon.
Though the early symptom of the cancer of the esophagus is more substantially, usual to be always mistakenly considered flu etc by people, therefore is often neglected Depending on, but do not know that the speed that cancer of the esophagus slowly deteriorates is very fast, once and feel increasingly apparent to be difficult to swallow, most likely Deteriorate as cancer.Afterwards may be by operation to the process of cancerization Regional resection, to reduce the death rate of cancer of the esophagus.
At present treatment cancer of the esophagus the best way is operation, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, suffer from Person's pain is difficult to stand, and success rate is also very low, and the life cycle after most Chemotherapy in Patients was with regard to 1 year or so --- certainly This is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some perform the operation, due to a variety of causes Hold and can't stand chemotherapy, can only palliative treatment, expect that miracle comes ...
The cancer of the esophagus is at present more refractory disease more as cancer of the stomach, all, but refractory representative cannot be controlled, except above-mentioned doctor trained in Western medicine Outside treatment method, the traditional Chinese medical science also has many effectively treatment methods.The traditional Chinese medical science is with organic conception according to the dialectical opinion of whole body feature of patient Control, go for various each phase cancer.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effect is light Micro-, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band knurl, and patient is easy to receive and expense Than less expensive.At present doctor trained in Western medicine is also considered as traditional Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, Improve cancer related symptoms, improve life quality, extend life cycle.But the problem for existing is that the prescription uniformity of the traditional Chinese medical science is poor, Treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always have in selected Chinese herbal medicine medicinal material --- it is most It is more than more than half --- medicine is all not proved function for cancer and acted on by modern medicine pharmacological evaluation " to distinguish Card treat " " compatibility " medicine, inventors believe that very improper;And folk prescription, folk prescription cure the disease lean on be test, often delay control The time of disease.
The content of the invention
The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and in the side's of curing the desease poor consistency, repeatability Poor, high level evidence-based medicine EBM is theoretical and evidence is relative lacks, thus the situation for mainly waiting deficiency by rule of thumb for cancer, proposition one The new dosage of kind and preparation method, there is provided one kind reduces the incidence of disease of the cancer of the esophagus from the beginning of prevention, starts to subtract from canceration Delay its tempo, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumour.Specifically, the present invention one is special Shi Yongyu esophageal ulcer before cancer not treated in case its canceration, two is can to treat cancer just ulcer, in case it continues to deteriorate, three It is inducible into the cancerous swelling atrophy apoptosis of knurl, with very low cost, fundamentally improves physical function, so as to recover strong Health.Its sharpest edges are to greatest extent to induce self apoptosis of cancer cell and differentiation, promote cancerous swelling progressively atrophy.In tool In the formula of body, also coordinate diagnosis and treatment based on an overall analysis of the illness and the patient's condition, induced because of esophageal injury, disease according to the origin cause of formation of cancer of the esophagus, dietary preferences nutrition is lost Weighing apparatus causes immunologic hypofunction, causes normal cell to be compromised because of Helicobacter pylori infection, apoptosis, and digestive tract ulcer, canceration " are taken advantage of It is empty and enter ", because " weakened body resistance poison is poly- ", " void in healthy tendency " and the characteristics of cause the basic pathology interpretation of the cause, onset and process of an illness such as metastases, with or righting dispel Heresy, orTonification and purgation in combination, or regulating qi to disperse stagnation, or solve strongly fragrant resolving sputum, or clearing heat and detoxicating, or reinforcing and reducing methods and the method used, with correct void in healthy tendency, Poly- and internal organs imbalance of yin and yang function reduction the deficiency of the solidifying poison of heresy, adjusts and improves the immunologic function of body, to reach overall tumor suppression Purpose, so as to improve the overall curative effect and late result of carninomatosis treatment, provides for esophageal cancer patients and a kind of is cured by modern Learn green high-tech Chinese herbal medicine formula and compound method that pharmacological evaluation proves function for cancer and effect, with very low or Relatively low cost, fundamentally improves physical function, and the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, and the final body that recovers is good for Health.Thus also to patient one according to the personal state of an illness, economic situation, personal inclination come consider select different treatment methods or Several method shares particularly traditional Chinese and western medicine and combines the leeway of complex treatment application, to obtaining optimum curative effect, easily improves life Deposit rate --- particularly more than 5 years survival rates.
Technical scheme proposed by the invention is:
Hui ethnic group's Chinese medicine root of the first, the described prevention and treatment cancer of the esophagus eats oesophagus and holds back cancer piece and preparation method thereof, is by following heavy Made by amount proportioning raw material:
Subprostrate sophora 30g, mushroom 15g, edible tulip 7g, bark of tree of heaven 11g,
Fruit of Chinese wolfberry 15g, Lu sand 1g, dandelion 15g field thistle 30g,
Radix Codonopsis 15g, Radix Astragali 15g, oldenlandia diffusa 30g
This side is substantially square for one decoction on the one.In practical application, can also be increased according to the physique of patient and conditions Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
In view of with this, basic side's decoction decoction of medicinal ingredients amount is big, taste is not good enough, patient is difficult to drink, therefore must apply special process It is prepared.
2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal tablet of the present invention:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Radix Codonopsis, all amplify 10 times, after clean water, be placed in BT- 2 stainless steels are extracted in kettle, plus after 7-9 times of running water, are heated to 100 DEG C of constant temperature and are extracted 1 hour or so, extraction fluid, plus Press filtration, filtrate is standby.
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract half an hour Left and right, extraction fluid, pressure filtration, filtrate is standby.
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes Left and right, extraction fluid, pressure filtration, filtrate is standby.
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), 80 DEG C are heated to, relative density 1.10~1.20 is concentrated into, it is standby.
(3), powder processed
Radix Codonopsis 15g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby.
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated.
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed.
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.
(9), compressing tablet
Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine(Also can coating), per piece 0.5g。
B, packaging
In first the tablet for pressing being fitted into vial or vinyon bottle, then by the bottle mounted box for installing, vanning, sterilizing ( Using 60Co irradiation, irradiation dose is 8kGy).
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
Routine instructions of taking of the invention:Three times a day, each 13-15 pieces, on an empty stomach (taking half an hour after can not drink water in a large number, in order to avoid Water down liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.
This medicine does medicine efficacy enhancing ingredient and takes better with pan-fried tomato soup.The specific practice of pan-fried tomato soup is:Take from so ripe Saturating little tomato(50 grams or so)Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate chopped spring onion, salt, treats chopped spring onion Blow out fragrance when the tomato of chopping poured into decoct in pot fry 1-2 minutes, then infuse to be got away into suitable quantity of water and take the dish out of the pot.
The effect of each raw material of the present invention:
Subprostrate sophora, beLegume root of subprostrate sophoraRoot.Bitter cold in nature.Effect is to relieve inflammation or internal heat, detoxifying, subsiding a swelling, pain relieving.Cure mainly:Laryngalgia, Sore-throat,Larynx numbness,Swelling and aching of gum,Breathe heavily fullHeat is coughed,Jaundice, diarrhea, heat is swollen,Mange, snakeworm dog bite.Its is rightThe cancer of the esophagusNasopharyngeal carcinoma、 Cervical carcinoma,Carcinoma of urinary bladder, leukaemia have inhibitory action.Composition pharmacology:Containing TA about 0.93%, whereinMatrine (Matrine) 0.52%,Oxymatrine(Oxymatrine) 0.35%, Yi JihanD-maackianin-β-D-glucoside(Sophoraponicin)、Red sandalwood Plain (Pterorepine),Screw oil expeller axleGrass roots glucoside (TrifolirhiZin),Albizzia kalkoraPlain (Maackian), sophoradin (Sophra) Deng.DNA and RNA synthesis of the subprostrate sophora to tumour cell has obvious inhibitory action, so as to block the propagation of tumour cell, can promote Enter lymphocyte transformation, excite or strengthen the CDCC of lymphocyte, improve T cell ratio, strengthen or adjustment macrophage is thin Born of the same parents' phagocytic function, moreover it is possible to adjust endocrine, strengthens adrenocortical function, thus affects the occurrence and development of tumour.
Mushroom, mushroom is cold in nature, mildly bitter flavor, favourable liver benefit stomachEffect.Mushroom not only has the peculiar flavour of delicate fragrance, and Containing abundant composition calcium, phosphorus, the iron beneficial to human body, also containing polysaccharide, vitamin B1, vitamin B2, vitamin C Deng.Containing compositions such as several amino acids, acetamide, choline, adenines in the infusion of dried thin mushroom, the courage that can be reduced in blood is consolidated Alcohol, atherosclerosis, to prevent and treat cerebral hemorrhage, heart disease, obesity andDiabetesIt is all effective.In recent years, American science Family find in mushroom containing it is a kind of " β-GrapeGlycosidase ", test proves that this material has the work for significantly strengthening body against cancer With, therefore, people call mushroom " anticancer new recruit ".Mushroom is also resistant toFluVirus, because containing a kind of interferon in mushroom Derivant, can induce the generation of internal interferon, the synthesis of viral interference protein so as to irreproducible, so that human body is produced Raw immunization.Ancient Times in China scholar early has found perfume (or spice)Mushroom based foodIt is improved the effect of function of brain cell.Such as《Legendary god of farming's book on Chinese herbal medicine》 In just have take bait mushroom can be with " increasing wisdom ", the record of " intelligence development is happy ".Modern medicine thinks that the increasing intelligence effect of mushroom is to contain There is abundant arginine and lysine, often eat, can be healthy and strong intelligence development.
Mountain is kind to eat, and nature and flavor are sweet, pungent, cool, mild toxicity.Return liver, kidney, lung, stomach,Large intestine channel.Drug effect:Internal heat anticance,DetumescenceDissipating bind.It is clinicalUsing:Suitable for kinds of tumors, it is mainly used inBreast cancer, also for malignant lymphoma, thyroid cancer,SkinCancer,Uterine neck Cancer, nasopharyngeal carcinoma, the cancer of the esophagus, leukaemia,Cancer of the stomachDeng.Additionally, applying also for carbuncle swells serious case of furuncle, scrofula, snake bite and benign swollen Knurl, such as thyroid adenoma, cystic hyperplasia of mammary gland, mammary gland fibroma, hemangioma.It is medicinal(1)Internal heat anticance, for carcinoma product poison.
Bark of tree of heaven, nature and flavorEffect:Root skin bitter, puckery, cold in nature, eliminating dampness heat-clearing, antidiarrheal, hemostasis.Fruit bitter, cool in nature, heat-clearing Diuresis, pain relieving, hemostasis.It is clinicalUsing:Suitable for colon and rectum carcinoma,Cervical carcinomaDeng.Additionally, CORTEX AILANTHI apply also for it is chronic Dysentery, enteritis, have blood in stool, pass out semen, leukorrhea, featureUterusBleeding.Fruit applies also for having a stomachache, has blood in stool, hematuria;Vagina is controlled in external application Trichomonad.
The fruit of Chinese wolfberry, matrimony vine is mild-natured, sweet, has functions that tonifying kidney and benefiting sperm, nourishing yin and supplementing blood, nourishes the liver to improve visual acuity, moistens the lung and relieve the cough, very All contain matrimony vine in the medicine of many health cares.Matrimony vine contains the life of amino acid, alkaloid, glycine betaine, wintercherry red pigment and various dimensions Element, also containing various linoleic acid.The effect of the fruit of Chinese wolfberry is with effect:1st, body's immunity is improved, strengthens organism adaptation and adjust Ability, the edible fruit of Chinese wolfberry can strengthen the body resistance to consolidate the constitution and the timid heresy of righting, not only strengthen body function, promote Health restoration, and can carry The resistance against diseases of high body, resists the infringement of disease and evil.Strengthen adaptability of the body to various destructive stimuluses.2nd, make with anticancer With, the fruit of Chinese wolfberry is to the generation of cancer cell and is diffused with obvious inhibitory action, the result of present age experiment and clinical practice shows, Chinese holly Qi leaf is often drunk for tea, can significantly improve and improve old man, valetudinarian andTumourThe immunologic function and physiological function of patient, tool There are strong human body and anti-aging.To cancer patient's combined with chemotherapy, there is mitigation toxic and side effect, prevent white blood cell from reducing, Adjust the curative effects such as immunologic function.Experimental study finds:The trace element germanium contained in matrimony vine piece has the work of obvious inhibition cancer cell With, it is completely severed can cancer cell, inhibiting rate is up to 100%.3rd, with significant function of improving eyesight, the fruit of Chinese wolfberry is particularly good at improving eyesight, institute To be also commonly called as " bright eye ".Blurring of vision and yctalopia that ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN cause, are frequently used The fruit of Chinese wolfberry.Famous prescription QIJU DIHUANG WAN, just with the fruit of Chinese wolfberry as key agents.It is among the people also to commonly use fruit of Chinese wolfberry treatment chronic ocular disease, It is exactly simple and effective dietotherapy side that matrimony vine steams egg.4th, with antifatigue effect, the fruit of Chinese wolfberry can dramatically increase muscle glycogen, hepatic glycogen Stockage, improves human activity, plays the role of antifatigue.5th, the hematopoiesis function of human body can be strengthened, the fruit of Chinese wolfberry is obviously promoted The effect of hematopoietic cell proliferation, can make Cervical mucus, strengthen the hematopoiesis function of human body.Except, the fruit of Chinese wolfberry contains abundant The polyphenoils such as LBP-X, beta carotene, vitamin E, selenium and flavonoids, have preferable antioxidation.The fruit of Chinese wolfberry Free radical peroxide injury can be mitigated to Green Tea Extract peroxidating, so as to contribute to anti-aging, extend the life-span.
Sal ammoniac, the crystal of halogenation species mineral sal ammoniac.Nature and flavorEffect:Taste is salty, bitter, pungent, warm in nature, poisonous.Disappear long-pending softening hard masses, Drastically removing blood stasis and resolving static blood.It is clinicalUsing:Suitable for kinds of tumors, such as the cancer of the esophagus,SkinCancer, nasopharyngeal carcinoma,Cervical carcinomaDeng.Additionally, being additionally operable to Amenorrhea, phlegm and retained fluid, larynx numbness, product dysentery, mesh screen, polyp, wart, furunculosis, carbuncle swells, evil sore etc..
Dandelion,Nature and flavor:Sweet, slight bitter is trembled with fear.Function:It is clearing heat and detoxicating, dispersing swelling and dissipating binds.Cure mainly:The infection of the upper respiratory tract,Eye knot FilmInflammation,Mumps,Acute mastitis swells and ache,Gastritis,Dysentery,Hepatitis, cholecystitis,Acute appendicitis,Urinary infection,Pelvic cavity It is scorching, carbuncleFuruncleFurunculosis,Pharyngitis, controlAcute mastitis,Lymph glandInflammation,Scrofula, malignant boil carbuncle toxin,Acute conjunctivitis,Cold, fever,It is anxious Property tonsillitis,Acute bronchitisUrinary tract infections.Its all herbal medicine, containing dandelionSterol, taraxerol, dandelion it is bitter Element,Caffeic acid, choline, the composition such as synanthrin.There is significant galgctogogue action, treatment mastitis is largely effective.No matter juice is decocted oral, also It is to smash mud external application, all there is effect.Additionally, dandelion also has diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogic, aid digestion, increasing appetite, treatmentStomach And duodenal ulcer, can also prevent and treatCancerCancer of the stomachThe cancer of the esophagusAnd the effects such as various cancers.
The Radix Astragali, the Radix Astragali is sweet, tepor.Returns spleen, lung channel.Tonifying spleen lung qi, yang invigorating, benefit defends solid table, diuresis, eliminating toxic life Flesh.The Radix Astragali is the dry root of legume astragalus mongolicus Astragalus membranacus.It is sweet containing amino acid, mucilaginous substance, carbohydrate, bitter principle, choline Dish alkali folic acid, kumatakenin, cupreol(, astragalus polyose etc..It is allCancerPatient is white because of spleen-lung Qi deficiency caused complexion white light, burnout It is powerless, receive few loose stool, hematemesis hematochezia, cough and asthma shortness of breath, abundant expectoration is dilute white, deficiency of QI with disinclination to talk, weak spontaneous perspiration, palpitation and insomnia, fever due to deficiency of vital energy, Edema oliguria etc. can use it.The Radix Astragali can strengthen the phagocytic function of reticuloendothelial system, there is facilitation to interferon system, right Cancer patient lymphocytes' function has completeness Immunonormalizing action, has fabulous curative effect to precancerous lesion gastric ulcer.
Radix Codonopsis, effect and effect:" tonifying middle-Jiao and Qi, promotes the production of body fluid, invigorating the spleen, and taste, relieving thirst and restlessness." traditional Chinese medical science thinks that Radix Codonopsis is mild-natured Sweet, returns spleen, lung channel the effect of have tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung, can be used for spleen and lung weakness, shortness of breath palpitations, anorexia and loose stool, void Breath with cough cough, the disease such as Heat Diabetes.And newest scientific research finds, the various nutriments contained in Radix Codonopsis are exempted to the body of people Epidemic disease power, blood vessel, and other organs are helpful.Radix Codonopsis can promote blood in human body in liquid to circulate, while also hematopoiesis regeneration, promotees Enter the effect of red blood cell growth.So as to effectively help people to strengthen body immunity, fitness is improved.Digestion of the Radix Codonopsis to people System has good opsonic action.Not only when pathology has occurred in the digestive system of people, it is possible to use Radix Codonopsis is treating Disease, such as can be nursed one's health when the gastroxia of people by taking Radix Codonopsis decoction, and, when usual just Some Radix Codonopsis can in advance be taken to prevent the disease of digestive system, and the health for promoting digestive system.Because Radix Codonopsis is to people Immune system also have certain opsonic action, therefore eat some Radix Codonopsis products, the immunocompetence that can make the person rises, Reduce the incidence of human body diseases.Except, Radix Codonopsis also adjusts cardio-cerebrovascular function, promotes cardio-cerebrovascular health Effect;Particularly there is hematopoiesis, blood pressure, the effect of reducing blood pressure etc. is adjusted.
Field thistle, meridian distribution of property and flavor:It is bitter, sweet, it is cool.The thoughts of returning home, Liver Channel.Effect:Cooling blood and hemostasis, removing toxicity for eliminating carbuncles.1. cooling blood and hemostasis, Go out blood trouble caused by for blood-heat bleeding.Such as haematemesis, spitting of blood, bleeding from five sense organs or subcutaneous tissue, uterine bleeding, hematuria.2. stasis of blood removing toxic substances is dissipated, for heat toxin carbuncle It is swollen.Effect:Field thistle contains alkaloid, saponin(e, rutin sophorin, originalCatechuAcid, caffeic acid etc..The bleeding time can substantially be shortened, be stopped blooding into It is divided into chlorogenic acid and caffeic acid, cholesterolemia can be reduced and have choleretic effect, to hemolytic streptococcus, Diplococcus pneumopniae, diphtheria Bacillus and tubercle bacillus etc., there is certain inhibitory action.Field thistle fries anastalsis after charcoal to strengthen, and decoction has to various pathogens Certain inhibitory action;This product also has the effects such as cholagogic, excited uterus, hypotensive, excited heart, anti-inflammatory, calmness, diuresis.
Long-noded pit viper house grass:Effect:It is clearing heat and detoxicating, diuresis of blood circulation promoting, Xiaofeng San gas, removing toxic substances detumescence, pain relieving.Cure mainly:Lung heat, intestines Heat, heat accumulating in the large intestine, laryngalgia, sore swells, snake sore, all enterodynia, appendicitis, tonsillitis, sphagitis, urinary tract infections, pelvic infecton, door screen Tail inflammation, hepatitis, bacillary dysentery, venomous snake bite, tumour.Also can be used for alimentary tract cancer.Modern pharmacology research proves, Hedyotidis Diffusae The immunity of body can be strengthened, suppress the growth of tumour cell, to Pseudomonas aeruginosa, staphylococcus aureus, pneumococcus, dysentery The pathogenic bacteria such as bacillus have inhibitory action, are in fact the good medicine of " clearing heat and detoxicating ".
Tomato, tomato has fat-reducingWeight reducing, dispelling fatigue, improve a poor appetite, improve the digestion to protein, reduce stomach The effects such as swollen dyspepsia.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, before tomato always occupies Row.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the tomato in cancer-resisting is mostly derived from it In lycopene.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, tomato red Element can promote Carcinoma cell differentiation (to good direction conversion), inhibition cancer cell propagation.Second, immune function of human body can be strengthened.Kind Lycopene can promote some to have the cytokine secretion of anti-cancer, antitumaous effect, such as interleukins-II, activated lymphocyte pair The dissolution of cancer cell;The lymphocyte being activated can discharge cytokine such as TNF etc. again, have to tumour cell There is lethal effect.3rd, lycopene has strongerIt is anti-oxidantEffect.Cell it is aging, damage and canceration all and free radical Effect is relevant, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein just It is included in protective effect on cancer risk and plays an important role.
The effect of the present invention:
Cure mainly:The cancer of the esophagus, particularly the early stage cancer of the esophagus, with very low cost, fundamentally improve physical function, control tumour after Continuous overgrowing simultaneously makes it that final disappearance is gradually reduced, so as to recover healthy.
It is simultaneous to control:The cancer in digestive system such as throat cancer, cardiac cancer, pylorus cancer, cancer of the stomach, colorectal cancer.
Our the characteristics of is:
1st, flavour of a drug, dosage are moderate, do not waste.
2nd, selected flavour of a drug are all to be proved that for cancer the cancer of the esophagus particularly can be treated by modern medicine pharmacological evaluation 's.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by Modern medicine pharmacological evaluation proves function for cancer with effect.
3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.Rather than only It is for cancer, just jump on the bandwagon, as a result it is that " dragon " does not harness the river on the contrary more.
4th, as much as possible " neutralisation ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.This Sample can just make patient suffer less within the cycle of whole medication, pull the devil by the tail less.And if really occurring " getting angry " or " under let out " Situation, then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " fall fire " are specifically solved for interim addition Certainly.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicine sides of being added to Son, makes patient all take always during very long very long medication, ultimately causes adverse consequences.
Specific embodiment:By subprostrate sophora 30g, mushroom 15g, edible tulip 7g, bark of tree of heaven 11g, fruit of Chinese wolfberry 15g, Lu sand 1g, Pu Public English 15g, Radix Codonopsis 15g, field thistle 30g, Radix Astragali 15g, oldenlandia diffusa 30g respectively amplify 10 times, after clean water, are placed in BT-2 Stainless steel is extracted in kettle, plus after 7-9 times of running water, is heated to 100 DEG C of constant temperature and is extracted 1 hour or so, extraction fluid, plus is pressed through Filter, filtrate is standby.Extract for second:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature extractions half little When or so, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted:Add in kettle the 3-5 times of running water measured toward extracting, It is heated to 100 DEG C of constant temperature to extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration:By the extraction of three times Liquid merges, and is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduces pressure (negative 200mmHg), is heated to 80 DEG C, concentration It is standby to relative density 1.10~1.20.Powder processed:Radix Codonopsis 15g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby.Match somebody with somebody Material:In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir. Drying, crushing:The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Make Grain:The spice being well mixed is inserted in comminutor and is granulated.Whole grain:The particle for making is carried out into whole grain, 35 mesh sieves are crossed.It is dried: Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C.Compressing tablet:By dry mixed gained Medicine adds magnesium stearate to be well mixed and is placed in compressing tablet in tablet press machine(Also can coating), per piece 0.5.Packaging:First by the piece for pressing Agent is fitted into vial or vinyon bottle, then (the bottle mounted box for installing, vanning, sterilizing are adopted into 60Co irradiation, spoke It is 8kGy according to dosage).Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine root eats oesophagus and holds back cancer piece and preparation method thereof, it is characterised in that it is by the raw material system of following weight proportion Into:
Subprostrate sophora 30g, mushroom 15g, edible tulip 7g, bark of tree of heaven 11g,
Fruit of Chinese wolfberry 15g, Lu sand 1g, dandelion 15g field thistle 30g,
Radix Codonopsis 15g, Radix Astragali 15g, oldenlandia diffusa 30g
This side is the substantially square of one decoction on the one, in practical application, can also be increased according to the physique of patient and conditions Theoretical " dialectical compatibility " medicine of the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert ".
2. the Hui ethnic group's Chinese medicine root according to claim 1 eats the weight proportion that oesophagus holds back cancer piece and preparation method thereof, its feature It is to include following preparation processes:
The preparation of A, extract
(1), extract
A, for the first time extraction:By the weight of said herbal medicine in addition to Radix Codonopsis 15g, all amplify 10 times, after clean water, be placed in BT-2 stainless steels are extracted in kettle, plus after 7-9 times of running water, are heated to 100 DEG C of constant temperature and are extracted 1 hour or so, extraction fluid, Pressure filtration, filtrate is standby;
B, second extraction:Add in kettle the 5-7 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, Extraction fluid, pressure filtration, filtrate is standby;
C, third time are extracted:Add in kettle the 3-5 times of running water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, Extraction fluid, pressure filtration, filtrate is standby;
(2), concentration
The extract of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), plus Heat is concentrated into relative density 1.10~1.20 to 80 DEG C, standby;
(3), powder processed
Radix Codonopsis 15g is amplified into 10 times, is crushed as end, cross 100 mesh sieves, it is standby;
(4), dispensing
In 300,000 grades of dust proof workshops, above-mentioned medicinal powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir;
(5), drying, crushing
The spice being well mixed is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves;
(6), granulate
The spice being well mixed is inserted in comminutor and is granulated;
(7), whole grain
The particle for making is carried out into whole grain, 35 mesh sieves are crossed;
(8), it is dried
Whole good particle is inserted in heat circulation drying oven, aeration-drying is to moisture < 8% at 80 DEG C;
(9), compressing tablet
Add magnesium stearate to be well mixed dry mixed gained medicine and be placed in compressing tablet in tablet press machine(Also can coating), per piece 0.5g;
B, packaging
In first the tablet for pressing being fitted into vial or vinyon bottle, then by the bottle mounted box for installing, vanning, sterilizing ( Using 60Co irradiation, irradiation dose is 8kGy);
C, warehouse-in
Irradiated finished product is put in storage by the principle of first in first out.
CN201510749263.7A 2015-11-08 2015-11-08 Hui nationality traditional Chinese medicine radix sophorae tonkinensis, lentinula edodes and pseudobulbus cremastrae seu pleiones esophagus cancer restraining tablet and preparation method thereof Withdrawn CN106668520A (en)

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Application publication date: 20170517