CN106668310A - Hui nationality traditional Chinese medicinal Cortex Acanthopanacis esophagus cancer treatment granule and preparation method thereof - Google Patents

Abstract

The invention concretely relates to a formula and a preparation method of a Hui Nationality traditional Chinese medicinal Cortex Acanthopanacis esophagus cancer treatment granule. The granule is a green high-tech Chinese herbal medicine used for treating the esophagus cancer. The granule is a traditional Chinese medicinal granule prepared through the following steps: mixing of glabrous sarcandra herb, Artemisia carvifolia, Cortex Acanthopanacis and other Chinese herbal medicines according to a certain ratio, water adding, decoction, extraction, concentration and granulation. The granule is mainly used for treating the esophagus cancer, and also is used for treating throat cancer, stomach cancer, colorectal cancer and other digestive system cancers. The granule has the characteristics of suitable medicine variety quantity and moderate dosage, and all the medicines are proved by modern medical science pharmacological experiments to be suitable for treating the cancers. The granule fundamentally improves the body functions and prevents and treats cancer cancerization at a low cost in order to recover the health of bodies.

Description

Hui ethnic group's Chinese medicine slender acanthopanax esophaguses Kangai Granula and preparation method thereof

Technical field

Hui ethnic group's Chinese medicine " slender acanthopanax esophaguses Kangai Granula " according to the present invention is a kind of green high-tech Chinese herbal medicine of the prevention and treatment esophageal carcinoma.The invention further relates to the preparation method of the medicine, belongs to Chinese medicine class.

Background technology

According to《China's tumour registration annual report in 2014》Data display, according to China's Life Calculation of 74 years old for each person, the probability that Chinese suffer from malignant tumor in all one's life is 22%, and average minute clock has 6 people to be diagnosed as malignant tumor, and tumor has become a kind of common disease in China.At present the cancer patient of China is about ten thousand people more than 700, and every year with the speed of more than 100 ten thousand people in increase.And the whole world

According to statistics, in the cancer patient of China nearly 8,000,000, have 31.27% for digestive system cancer patient, wherein patient with esophageal carcinoma accounts for the 29.7% of digestive system cancer patient, almost half.

Esophageal carcinomaDisease locus are typically organized in epithelium of esophagus, and it is exactly swallowing and digestive function for patient that it directly affects, and health is slowly etched with regard to this.The pathogenic factor of esophageal carcinoma mainly has three, and one is malnutrition, though that is, now the living standard of people improves, due to the change of diet hobby and mode, will also result in the shortage of malnutrition and trace element；Two is that diet is lack of standardization, and in the grain and drinking-water of district occurred frequently, nitrate, nitrite and secondary amine content significantly increase, and these materials are easily-synthesized carcinogen nitrosamine in gastric；Three is esophageal injury and disease induction, and esophageal injury and some esophagel diseases are likely to become the inducement for causing esophageal carcinoma, and long-term chronic inflammatory disease, ulcer, or chronic stimulation, and then esophageal epithelial proliferation are caused because of being detained in esophaguses, finally result in canceration.Although esophageal carcinoma does not possess infectiousness, the destruction to human body is but not allow to look down upon.

Though the early symptom of the esophageal carcinoma is more substantially, generally always flu etc is mistakenly considered by people, therefore often ignored, but do not know that the speed that esophageal carcinoma slowly deteriorates is very fast, once and feel increasingly apparent to be difficult to swallow, most likely deteriorated as cancer.Afterwards may be by operation to the process of cancerization Regional resection, to reduce the mortality rate of esophageal carcinoma.

At present treatment esophageal carcinoma the best way is operation, postoperative to be also performed to chemotherapy, and chemotherapy not only large side effects, patient suffering is difficult to stand, and success rate is also very low, the life cycle after most Chemotherapy in Patients was with regard to 1 year or so --- certainly this is also relevant with the over-treatment given birth to without skilful doctor.And on the other hand, although some perform the operation, held due to a variety of causes and can't stand chemotherapy,Can only palliative treatment, expect that miracle comes ...

The esophageal carcinoma is disease at present compared with refractory more as gastric cancer, all, but refractory is not represented and cannot controlled, and in addition to above-mentioned western medical treatment method, the traditional Chinese medical science also has many effectively Therapeutic Method.The traditional Chinese medical science, according to the whole body feature determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of patient, goes for various each phase cancer with organic conception.The advantage of Chinese medicine cancer is to be conducive to stablizing the state of an illness, and toxic and side effects are slight, symptom improves more apparent, slows down PD, tumor regression or the longer-term existence of band tumor, and patient is easy to receive and expense is than less expensive.At present doctor trained in Western medicine is also considered as Chinese medicine can contribute to reducing the toxicity of Radiotherapy chemotherapy as the auxiliary treatment of cancer, improve cancer related symptoms, improve life quality, extend life cycle.But exist problem be the traditional Chinese medical science prescription uniformity it is poor, treatment mainly be experience.From in terms of existing proved recipe for cancer, folk prescription, always there is --- majority is more than more than half --- medicine to be all not prove " compatibility " medicine of function for cancer and effect " determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs " by modern medicine pharmacological evaluation in selected Chinese herbal medicine medical material, inventors believe that very improper；And folk prescription, folk prescription cure the disease lean on be test, often stop over the time cured the disease.

The content of the invention

The purpose of the present invention, be aiming at Cancer in China patient assessment be difficult to and the traditional Chinese medical science see a doctor standardization it is poor, it is repeatable it is poor, lack high level evidence-based medicine EBM theory and evidence, thus the situation for waiting deficiency by rule of thumb that is mainly for cancer, propose a kind of new dosage and preparation method, there is provided a kind of from the beginning of prevention, the sickness rate of the esophageal carcinoma is reduced, starts to slow down its tempo from canceration, the green high-tech Chinese herbal medicine for inducing its atrophy apoptosis is started from tumor.Specifically, the present invention one is particularly suited for use in esophageal ulcer before treatment cancer in case its canceration, two is can to treat cancer just ulcer, in case it continues to deteriorate, three is inducible into the cancerous protuberance atrophy apoptosis of tumor, with very low cost, fundamentally improve physical function, so as to get well.Its sharpest edges are to greatest extent to induce self apoptosis of cancerous cell and differentiation, promote cancerous protuberance progressively atrophy.In specific formula, also coordinate determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, induced because of esophageal injury, disease according to the origin cause of formation of esophageal carcinoma, dietary preferences nutrient imbalance causes immunologic hypofunction, cause normal cell to be compromised because of Helicobacter pylori infection, apoptosis, digestive tract ulcer, canceration " taking advantage of a weak point ", because " weakened body resistance poison poly- ", " healthy energy interior-deficiency " and the characteristics of causes the basic pathology pathogenesis such as neoplasm metastasis, utilization or strengthening vital QI to eliminate pathogenic factors, orReinforcement and elimination in combination, or regulating qi to disperse stagnation, or resolving depression resolving sputum, or heat-clearing and toxic substances removing, or reinforcing and reducing and the method used, to correct healthy energy interior-deficiency, poly- and internal organs imbalance of YIN and YANG function reduction the deficiency of the solidifying poison of heresy, adjust and improve the immunologic function of body, to reach the purpose of overall tumor suppression, so as to improve the overall curative effect and late result of carninomatosis treatment, a kind of green high-tech Chinese herbal medicine formula and compound method that function for cancer and effect are proved by modern medicine pharmacological evaluation is provided for esophageal cancer patients, with very low or relatively low cost, fundamentally improve physical function, the deterioration of symptom management simultaneously makes the state of an illness gradually take a turn for the better, finally recover healthy.Thus also to patient one select different treatment methods or several method to share particularly Chinese and western medicine to combine the leeway of Comprehensive Treatment application to consider according to the personal state of an illness, economic situation, personal inclination, to obtaining optimum curative effect, survival rate is easily improved --- particularly more than 5 years survival rates.

Technical scheme proposed by the invention is：

First, Hui ethnic group's Chinese medicine " slender acanthopanax esophaguses Kangai Granula " of the described prevention and treatment esophageal carcinoma and preparation method thereof, is by made by following weight proportion raw material：

Herba Sarcandrae 50g, Radix Gossypii 30g, Herba Artemisiae Annuae 9g, Herba Scutellariae Barbatae 20g,

Herba Salviae Chinensiss 10g, Fructus Fici 9g, Cortex Eucommiae 9g, Cortex Acanthopanciss 9g,

Fructus Lycii 15g, Fructus Lycopersici esculenti 50g

This side is substantially square for one decoction on the one.In practical application, also the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory can be increased according to the body constitution of patient and conditions“Dialectical compatibility " medicine.

In view of with this, basic side's decoction decoction amount is big, taste is not good enough, patient is difficult to drink, therefore must be prepared using special process.

2nd, it is by the preparation method that above-mentioned each raw material makes Chinese medicinal granule of the present invention：

A, extract preparation

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to Fructus Fici, the Cortex Eucommiae, Fructus Lycopersici esculenti, all amplify 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.

B, second extraction：Add in kettle the 5-7 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.

C, third time are extracted：Add in kettle the 3-5 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.

（2）, concentration

The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.

（3）, powder processed

Fructus Fici 9g, Cortex Eucommiae 9g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.

（4）, dispensing

In 300,000 grades of dust proof workshops, above-mentioned medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir.

(5) drying, crushing

The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.

(6) pelletize

The spice of mix homogeneously is inserted into pelletize in comminutor.

(7) granulate

The granule for making is carried out into granulate, 35 mesh sieves are crossed.

(8) it is dried

Whole good granule is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.

B, packaging

First the granule for making is fitted in vinyon pouch, every bag of 8g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.

, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.

Routine instructions of taking of the invention：Three times a day, 1 bag of 8g every time, on an empty stomach, is taken better (taking half an hour after can not drink water in a large number, in order to avoid water down medicinal liquid) with decocting tomato soup and doing extra conductant ingredient.The specific practice of pan-fried tomato soup is：Take from so well-done little tomato（50 grams or so）Chopping, puts 10 grams or so vegetable oil in pot, heat, and is put into appropriate Flos Allii Fistulosi, Sal, pours into be decocted in pot by the Fructus Lycopersici esculenti of chopping when Flos Allii Fistulosi blows out fragrance and fries 1-2 minutes, then infuses to be got away into suitable quantity of water and take the dish out of the pot.(taking half an hour after can not drink water in a large number, in order to avoid water down medicinal liquid).The pungent grade food larger to gastrointestinal irritation is not eaten during medication.

The effect of each raw material of the present invention：

Herba Sarcandrae,Nature and flavorEffect：Acrid in the mouth, it is mild-natured.Heat-clearing and toxic substances removing, expelling wind and removing dampness, promoting blood circulation and stopping pain.It is clinicalUsing：Suitable for kinds of tumors, such as the esophageal carcinoma,Gastric cancer, colon and rectum carcinoma, cancer of pancreas, hepatocarcinoma, acute leukemia etc..

Radix Gossypii,Nature and flavorEffect：Sweet in the mouth, warm in nature, QI invigorating, Zhichuan is relievingd asthma.Cotton root bark containsGossypol, flavone, Acetovanillone,Glycine betaine, sterol,Salicylic acidDeng；Root containsSaponin,PhenolComposition；Gossypium hirsutum L. contain gossypol, cotton purpurin,Arginine,Radix AsparagiAmide, glycine betaine,Oxalic acid, salicylic acid,Oleic acid,Palmic acidAnd it is a small amount ofVolatile oil, contain in volatile oilFurfural, Acetovanillone.It is clinicalUsing：Suitable for kinds of tumors, such as pulmonary carcinoma, hepatocarcinoma, spermatogonium cancer,Gastric cancer, the esophageal carcinoma and bottleneck throat tumor etc..Additionally, being also suitable for chronic bronchitiss, body void edema, sub-official prolapses etc..

Herba Artemisiae Annuae,Nature and flavor：It is bitter, cold.Return through：Enter liver, gallbladder meridian.For the stem and leaf harvested before Compositae is annual or biennial herb plant Herba Artemisiae annuae or Herba Artemisiae Annuae are bloomed, wild main component：Containing arteannuin, volatile oil and amaroid etc..Pharmacological action：1st, thermal sweating is solved.It is especially suitable for heat clearing away summer-heat and unwind is speeded the not clear long heat of a heat and reason.2nd, stop blooding.To epistaxiss and purpura, there is certain therapeutic effect.Function：Clearing away heat and cooling blood, expelling summer-heat is except steaming.Cure mainly：Pathogenic summer-heat is generated heat, fever due to yin deficiency, malaria, hectic fever due to YIN-deficiency consumptive fever.Clinical practice：It is mainly used in heat clearing away deficiency-heat river summer-heat.The experience of forefathers is said：" Herba Artemisiae Annuae moves back the good medicine of steaming for clearing away heat and cooling blood ", modern practice is also mainly used for blood deficiency and has hot person.

Herba Scutellariae Barbatae,Effect and effect are heat-clearing and toxic substances removing, and dissipate stasis of blood hemostasis, inducing diuresis to remove edema is controlled pyretic toxicity carbuncle, had sore throat, lung abscess, acute appendicitis, venom, traumatic injury；Spit blood；Epistaxis；Stranguria with blood；It is swollen；Ascites and cancer.Effect has Herba Scutellariae Barbatae Radix Astragali eliminating mass ball, four aurification stasis of blood Paishi Tangs, Herba Scutellariae Barbatae qi-restoratives dampness-eliminating soup with effect and eating method.

Herba Salviae Chinensiss,For the herb of Labiatae annual herb plant Herba Salviae Chinensiss, flavor efficacy：It is bitter in the mouth, mild-natured.Heat-clearing and toxic substances removing, cool blood flat liver, inducing diuresis to remove edema, eliminating stagnation.Clinical practice：It is usually used in treating the esophageal carcinoma, carcinoma of parotid gland, hepatocarcinoma, gastric cancer, carcinoma of gastric cardia etc..Medical science religion ' educate net compile additionally, be additionally operable to treat viral hepatitis, summer-heat dysentery, infantile acute nephritis, edema, rheumatic arthritis, chyluria, treating swelling and pain by traumatic injury, venom, furuncle swell and ache, metrorrhagia etc..

Fructus Fici,Fructus Fici is a kind of rare fruit, with many magical effects.Energy anticancer, invigorating the stomach and promoting bowel movement, subduing swelling and detoxicating.Control enteritis, dysentery, constipation, hemorrhoid, laryngalgia, ulcerative carbuncle scabies, throat, anthelmintic of whetting the appetite.For diseases such as inappetence, abdominal distention, constipation due to hemorrhoids, dyspepsia, hemorrhoid, proctoptosis, diarrhoea, hypogalactia, laryngopharynx swelling and pain, hematodiarrhoea, cough ant phlegms.Fructus Fici contains polysaccharide, accounts for 6.49% (dry weight), predominantly arabinose and galactose, has certain effect to defying age.Fructus Fici contains multivitamin, and particularly containing more carotene, fresh fruit is 30 milligrams/100 grams, and dry fruit is 70 milligrams/100 grams, is occupy more than Fructus Persicae, Fructus Vitis viniferae, prunus mume (sieb.) sieb.et zucc., pears, mandarin orange, sweet persimmon.Fructus Fici contain it is a large amount of it is beneficial to human body have inorganic elemental composition, and do not contain the inorganic elementss such as easily carcinogenic Co, Cd, Pb, it is healthy to enhancing body and anti-cancer ability has good action.

Cortex Acanthopanciss,Meridian distribution of property and flavor：Pungent, hardship, temperature.People's liver and kidney channel.Effect：Wind-damp dispelling, strengthening bone and muscle, blood circulation and promoting silt.Control anemofrigid-damp arthralgia, muscles and bones contraction urgency, lumbago, sexual impotence, flaccidity of the lower limbs, children's walking retardation in children, edema, tinea pedis, skin ulcer cellulitis toxic swelling, traumatic injury impairment caused by overstrain.Effect：This product is warm in nature, the warm promoting blood circulation of energy, there is the work(of blood circulation promoting and blood stasis dispelling, for exogenous injury or traumatic injury, there is the stagnant effect of blood circulation promoting and blood stasis dispelling, logical solidifyingization, has tonic effect again, to promote early healing.Bushen Yizhi; antiinflammatory; calm, analgesia, resisting fatigue strengthens macrophage inducement interferon; T cell, NK cells, K cells, the effect of macrophage killing tumor cell can be strengthened; leukocyte increasing, can be obviously promoted the formation of myeloid lineage progenitor population, there is significantly protection and leukocyte rising effect to the bone marrow depression that chemotherapy radiotherapy causes; removing toxic substances, also with antitumor action.Herba Salviae Chinensiss,For the herb of Labiatae annual herb plant Herba Salviae Chinensiss, flavor efficacy：It is bitter in the mouth, mild-natured.Heat-clearing and toxic substances removing, cool blood flat liver, inducing diuresis to remove edema, eliminating stagnation.Clinical practice：It is usually used in treating the esophageal carcinoma, carcinoma of parotid gland, hepatocarcinoma, gastric cancer, carcinoma of gastric cardia etc..Medical science religion ' educate net compile additionally, be additionally operable to treat viral hepatitis, summer-heat dysentery, infantile acute nephritis, edema, rheumatic arthritis, chyluria, treating swelling and pain by traumatic injury, venom, furuncle swell and ache, metrorrhagia etc..

The Cortex Eucommiae,It is Chinese famous and precious tonic herb for the dry bark of the Eucommiaceae plant Cortex Eucommiae.Nature and flavor：It is sweet；Micro-pungent；It is warm in nature.Return through：Liver Channel；Kidney channel.Effect：Invigorating the liver and kidney；Bone and muscle strengthening；Antiabortive gas.The Cortex Eucommiae has invigorating the liver and kidney, and internal rubbish are removed in bone and muscle strengthening, strengthen human body cell metabolism, prevent muscle skeleton aging, balanced human's blood pressure, decomposer inner cholesterol, body fat is reduced, recovers blood vessel elasticity, diuresis heat-clearing, broad-spectrum antiseptic, stimulating central nervous system, improves white blood cell count, strengthens the remarkable efficacies such as body immunity.Cure mainly：Spinal column ache；Sexual impotence；Frequent micturition；Dribbling urination；Rheumatic arthralgia；Frequent fetal movement；Habitual abortion.It is applied to：1st, instability of kidney QI：Card is shown in frequent micturition or dripping urination, uncontrolled urination, sexual impotence, weak anemia of pregnant woman, frequent fetal movement or waist pendant pain etc..It is more common in chronic prostatosiss, sexual dysfunction, infertility, threatened abortion or habitual abortion etc..2nd, caused by liver and kidney deficiency：Card is shown in that dizziness, soreness of waist and knee joint, muscles and bones flaccidity are weak etc..It is more common in hypertension, vertigo, apoplexy sequela, chronic renal disease, poliomyelitis etc..3rd, there is caused by liver and kidney deficiency sign person for diseases such as chronic joint diseases, bone tuberculosis, dysmenorrhea, dysfunctional uterine bleeding, chronic pelvic inflammatory diseases.

Fructus Lycii,Fructus Lycii is mild-natured, sweet in the mouth, has functions that the kidney invigorating and essence nourishing, nourishing YIN and supplementing blood, nourishing the liver to improve visual acuity, nourishing the lung to arrest cough, and Fructus Lycii is all contained in the medicine of many health cares.Fructus Lycii contains aminoacid, alkaloid, glycine betaine, Calyx seu fructus physaliss red pigment and multivitamin, also containing various linoleic acids.The effect of Fructus Lycii is with effect：1st, improve body's immunity, enhancing body adapts to regulating power, edible Fructus Lycii can be with strengthening the body resistance and the timid heresy of righting, not only enhancing body function, promote Health restoration, and the resistances against diseases of body can be improved, resist the infringement of pathogenic factor.Adaptability of the enhancing body to various destructive stimuluses.2nd, with antitumaous effect, Fructus Lycii is to the generation of cancerous cell and is diffused with obvious inhibitory action, and the result of present age experiment and clinical practice shows that Folium Lycii is often drunk for tea, can significantly improve and improve old man, valetudinarian andTumorThe immunologic function and physiological function of patient, the effect with strong human body and slow down aging.To cancer patient's combined with chemotherapy, there are mitigation toxic and side effects, prevent leukopenia, adjust the curative effects such as immunologic function.Experimental study finds：The trace element germanium contained in Fructus Lycii piece plays the role of obvious anticancer, is completely severed can cancerous cell, and suppression ratio is up to 100%.3rd, with significant function of improving eyesight, Fructus Lycii is particularly good at improving eyesight, so being also commonly called as " bright eye ".Blurring of vision and nyctalopia that ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN cause, are frequently used Fructus Lycii.Famous prescription QIJU DIHUANG WAN, just with Fructus Lycii as key agents.Among the people also to commonly use Fructus Lycii treatment chronic ocular disease, it is exactly simple and effective dietetic therapy side that Fructus Lycii steams egg.4th, with antifatigue effect, Fructus Lycii can dramatically increase the stockage of muscle glycogen, hepatic glycogen, improve human activity, there is resisting fatigue.5th, the hemopoietic function of human body can be strengthened, Fructus Lycii is obviously promoted hematopoietic cell proliferation, Cervical mucus can be made, strengthen the hemopoietic function of human body.Except, Fructus Lycii contains the antioxidant such as abundant lycium barbarum polysaccharide, beta-carotene, Vitamin E, selenium and flavonoid, there is preferable antioxidation.Fructus Lycii can mitigate free radical peroxide injury to free radical resisting peroxidating, so as to contribute to slow down aging, extend the life-span.

Fructus Lycopersici esculenti,Fructus Lycopersici esculenti has fat-reducing Weight reducing , allaying tiredness, appetite stimulator, raising to the digestion of protein, reduce flatulence food stagnation the effects such as.In recent years, in the anti-cancer or health food that numerous worldwide organizations are recommended, Fructus Lycopersici esculenti always ranks among the best.Find in substantial amounts of epidemiological survey and zoopery, outstanding representation of the Fructus Lycopersici esculenti in cancer-resisting is mostly derived from lycopene therein.So, lycopene be how to give protection against cancer, the first of anticancer, by a series of biochemical action, lycopene can promote Carcinoma cell differentiation (to good direction conversion), anticancer propagation.Second, immune function of human body can be strengthened.Lycopene can promote some to have anti-cancer, the such as secretion of the cytokines of antitumaous effect, interleukin-II, dissolution of the activated lymphocyte to cancerous cell；The lymphocyte being activated can discharge cytokines such as tumor necrosis factor etc. again, have lethal effect to tumor cell.3rd, lycopene has stronger Antioxidation Effect.The aging of cell, damage are all relevant with Free Radical with canceration, and antioxidant (such as lycopene) is effectively removing free radical, so as to play whole body health-care effect, wherein be just included in protective effect on cancer risk playing an important role.

The effect of the present invention：

Cure mainly：The esophageal carcinoma, particularly the early stage esophageal carcinoma, with very low cost, fundamentally improve physical function, and control tumor continues to overgrow and makes it that final disappearance is gradually reduced, so as to recover healthy.

It is simultaneous to control：The cancer in digestive system such as laryngocarcinoma, cardiac cancer, pylorus cancer, gastric cancer, colorectal cancer.

Our the characteristics of is：

1st, flavour of a drug are more, and dosage is moderate, do not waste.

2nd, selected flavour of a drug are all to be proved that for cancer the esophageal carcinoma particularly can be treated by modern medicine pharmacological evaluation.And then always have in existing proved recipe for cancer, folk prescription --- even more than medicine more than half be all not by modern medicine pharmacological evaluation proved function for cancer and effect.

3rd, for focus, arrow arrow punching, i.e., selected flavour of a drug all especially grow tender of and hit the bull's eye, and As the medicine took effect, the symptoms lessened.As long as rather than it is for cancer, just jump on the bandwagon, be as a result that " dragon " does not harness the river on the contrary more.

4th, as much as possible " neutralization ", i.e., selected flavour of a drug generally keep " neutrality ", do not tremble with fear not dry, not hot not cool.Patient can be thus set to suffer less within the cycle of whole medication, pull the devil by the tail less.And if really there is the situation of " getting angry " or " under let out ", then can be directed to concrete individual concrete condition completely, a bit " stopping leak ", the medicine of " pathogenic fire reducing " are specifically solved for interim addition.Rather than imagine at the very start patient may on tell or drop, and some unnecessary medicines are added to prescription, patient is all taken always during very long very long medication, ultimately cause adverse consequencess.

Specific embodiment：Herba Sarcandrae 50g, Radix Gossypii 30g, Herba Artemisiae Annuae 9g, Herba Scutellariae Barbatae 20g, Herba Salviae Chinensiss 10g, Cortex Acanthopanciss 9g, Fructus Lycii 15g are respectively amplified into 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, it is heated to 100 DEG C of constant temperature to extract 1 hour or so, extraction fluid, pressure filtration, filtrate is standby.Extract for second：Add in kettle the 5-7 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby.Third time is extracted：Add in kettle the 3-5 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby.Concentration：The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby.Powder processed：Fructus Fici 9g, Cortex Eucommiae 9g are respectively amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby.Dispensing：In 300,000 grades of dust proof workshops, above-mentioned medicated powder is put in mixer together with aforementioned concentrate and 30g Mel and is sufficiently mixed, stir.Drying, crushing：The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves.Pelletize：The spice of mix homogeneously is inserted into pelletize in comminutor.Granulate：The granule for making is carried out into granulate, 35 mesh sieves are crossed.It is dried：Whole good granule is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C.Packaging：First the pill for making is fitted in vinyon pouch, every bag of 8g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）.Finally, irradiated finished product is put in storage by the principle of first in first out.

Claims (2)

1. Hui ethnic group's Chinese medicine slender acanthopanax esophaguses Kangai Granula and preparation method thereof, it is characterised in that it is by made by the raw material of following weight proportion：

Herba Sarcandrae 50g, Radix Gossypii 30g, Herba Artemisiae Annuae 9g, Herba Scutellariae Barbatae 20g,

Herba Salviae Chinensiss 10g, Fructus Fici 9g, Cortex Eucommiae 9g, Cortex Acanthopanciss 9g,

Fructus Lycii 15g, Fructus Lycopersici esculenti 50g

This side is the substantially square of one decoction on the one, in practical application, can also increase the 1-3 taste traditional Chinese medical science " harmony between man and nature, dialectical treatmert " theory according to the body constitution of patient and conditions“Dialectical compatibility " medicine.

2. the weight proportion of the Hui ethnic group's Chinese medicine slender acanthopanax esophaguses Kangai Granula according to claim 1, it is characterised in that including following preparation processes：

A, extract preparation

（1）, extract

A, for the first time extraction：By the weight of said herbal medicine in addition to Fructus Fici, the Cortex Eucommiae, Fructus Lycopersici esculenti, all amplify 10 times, after clean water, it is placed in BT-2 rustless steels to extract in kettle, plus after 7-9 times of tap water, is heated to 100 DEG C of constant temperature and extracts 1 hour or so, extraction fluid, pressure filtration, filtrate is standby；

B, second extraction：Add in kettle the 5-7 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract or so half an hour, extraction fluid, pressure filtration, filtrate is standby；

C, third time are extracted：Add in kettle the 3-5 times of tap water measured toward extracting, be heated to 100 DEG C of constant temperature and extract 20 minutes or so, extraction fluid, pressure filtration, filtrate is standby；

（2）, concentration

The extracting solution of three times is merged, is placed in B-500 type triple effect vacuum high energy evaporation concentrators, reduced pressure (negative 200mmHg), be heated to 80 DEG C, be concentrated into relative density 1.10～1.20, it is standby；

（3）, powder processed

Fructus Fici 9g, Cortex Eucommiae 9g are amplified into 10 times, it is end together to crush, cross 100 mesh sieves, it is standby；

（4）, dispensing

In 300,000 grades of dust proof workshops, above-mentioned medicated powder is put in mixer together with aforementioned concentrate and is sufficiently mixed, stir；

(5) drying, crushing

The spice of mix homogeneously is placed in into 60-70 DEG C of baking 4-5 hour in baking oven, is then crushed, cross 100 mesh sieves；

(6) pelletize

The spice of mix homogeneously is inserted into pelletize in comminutor；

(7) granulate

The granule for making is carried out into granulate, 35 mesh sieves are crossed；

(8) it is dried

Whole good granule is inserted in heat circulation drying oven, aeration-drying is to moisture ＜ 8% at 80 DEG C；

B, packaging

First the pill for making is fitted in vinyon pouch, every bag of 8g, then the pouch mounted box for installing, vanning, sterilizing (are adopted into 60Co irradiation, irradiation dose is 8kGy）；

C, warehouse-in

Irradiated finished product is put in storage by the principle of first in first out.