CN106668269A - Externally-applied traditional Chinese medicine for treating psoriasis - Google Patents

Externally-applied traditional Chinese medicine for treating psoriasis Download PDF

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Publication number
CN106668269A
CN106668269A CN201710215741.5A CN201710215741A CN106668269A CN 106668269 A CN106668269 A CN 106668269A CN 201710215741 A CN201710215741 A CN 201710215741A CN 106668269 A CN106668269 A CN 106668269A
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chinese medicine
traditional chinese
treating psoriasis
externally
patients
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CN201710215741.5A
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Chinese (zh)
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张鹏
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicine, and in particular discloses an externally-applied traditional Chinese medicine for treating psoriasis. The externally-applied traditional Chinese medicine for treating psoriasis is characterized by the raw materials in proportions by weight (grams in unit): 3-6 of coptis root, 5-10 of phellodendron bark, 5-10 of cortex dictamni, 5-10 of sulfur, 10-20 of broom cypress fruits, 10-20 of cnidium fruits, 10-20 of flavescent sophora root and 10-15 of radix bistortae. The traditional Chinese medicine achieves the effect of treating psoriasis through clearing away heat and toxic material, eliminating dampness, dispelling wind and arresting itching. The traditional Chinese medicine has obvious curative effects, greatly relieves suffering of patients, obviously reduces the recurrence rate, improves the life quality of patients, has relatively small toxic side effects and can be administered by patients securely. The traditional Chinese medicine has good curative effects, high effect-taking speed, no side effects and high total effective rate of 96.0%.

Description

One kind treats psoriatic external application Chinese medicine
Technical field
The invention mainly relates to the field of Chinese medicines, more particularly to one kind treats psoriatic external application Chinese medicine.
Background technology
Psoriasis is commonly called as psoriasis, is a kind of chronic inflammatory skin, and the course of disease is longer, there is easy tendency of recurrence, some diseases Example almost cannot be cured all one's life.The disease is fallen ill based on person between twenty and fifty, affects larger to the healthy and mental status of patient.Clinical table Now with erythema, based on the scales of skin that peel off, whole body can fall ill, and with scalp, it is relatively conventional that four limbs stretch side, increases in the winter time more.The disease of this disease Because the interpretation of the cause, onset and process of an illness is varied, such as skin loses and supports, and attacks outside ailment said due to cold or exposure;The evil invasion and attack of rheumatism poison, cause stagnation of QI-blood;Blood-head is jammed, disorder of qi, Failure of skin and muscle to be nourished;Caused by liver and kidney deficiency, skin is lost in making moist, exopathogen invasion and attack etc..Arthropathic psoriasis its infringement be homeliness type silver consider to be worth doing Occur on the basis of disease with the Minor articulus congestion and swelling pain such as hand, wrist, foot, pathology is in fusiformis swelling compared with elder, and patient's course of disease is longer, instead Recurrence is made, and does not heal for many years, and skin damaged is purple dark or has pigmentation, and the scales of skin that peel off is thicker, likeness in form oyster shell, and joint motion is unfavorable etc..
Psoriatic method is treated at present, doctor trained in Western medicine there is no specific short, substantially based on symptomatic treatment, control symptom.It is main There are conjoint therapy, rotational therapy, sequential and intermittent treatment etc..Externally applied drug has vitamin D 3 analogs, glucocorticoid, anthracene Woods, Avita Gel and creme, tar class, immunodepressant etc.;Medicine for oral administration has methotrexate (MTX) (MTX), tretinoin, sugared cortical hormone Element;Immunodepressant, the antibiotic such as ciclosporin A, tacrolimus, mould fragrant acid esters etc.;Physical therapy has ultraviolet, photochemotherapy (PUMA), wide range ultraviolet B radiation(BB-UVB)Therapy, narrow-band UVB(NB-UVB)Therapy, hydrotherapy etc..
Because this disease is a kind of chronic relapsing disease, many patients need long-term medical, and various therapies have necessarily Bad reaction, and be also easy to produce tolerance, cure the symptoms, not the disease, easily repeatedly.Traditional Chinese Medicine emphasizes organic conception, association due to having Negative and positive are adjusted, treated both principal and secondary aspect of disease, the advantages of toxic and side effect is little, increasingly approved by people.
The content of the invention
The object of the invention is exactly to make up the defect of prior art, there is provided in a kind of psoriatic external application of special for treating Medicine, it is obvious for treatment psoriasis curative effect, safe ready, Small side effects.
The present invention is achieved by the following technical solutions:
One kind treats psoriatic external application Chinese medicine, it is characterised in that:The weight proportion of each raw material(Unit g)For:
Coptis 3-6, golden cypress 5-10, root bark of shaggy-fruited dittany 5-10, sulphur 5-10, fruit of summer cypress 10-20, frutus cnidii 10-20, kuh-seng 10-20, fist Ginseng 10-15.
One kind treats psoriatic external application Chinese medicine, and it is preferably:The weight proportion of each raw material(Unit g)For:
The coptis 5, golden cypress 5, the root bark of shaggy-fruited dittany 8, sulphur 10, the fruit of summer cypress 15, frutus cnidii 15, kuh-seng 15, adder-wort 12.
When being treated, the mixing of above raw material is ground, pasty state is sufficiently stirred for into by sesame oil or vinegar immersion, external application is suffered from Place, three times a day.
Specific embodiment:
One kind treats psoriatic external application Chinese medicine, and it is preferably:The weight proportion of its each raw material(Unit g)For:
The coptis 5, golden cypress 5, the root bark of shaggy-fruited dittany 8, sulphur 10, the fruit of summer cypress 15, frutus cnidii 15, kuh-seng 15, adder-wort 12.By the mixing of above raw material Grind, soaked by sesame oil or vinegar and be sufficiently stirred for into pasty state, external application affected part, three times a day.
Clinical observation:
1 data and method
1.1 physical data
Inclusive criteria:1. reference《New Chinese medicine guideline of clinical investigations》, Ou Yangheng chief editor《Newly organized Dermatology of Traditional Chinese Medicine》 Meet psoriatic traditional Chinese and western medicine diagnostic criteria;2. age 18~65 years old;3. non-system receives anti-curing psoriasis in nearly 1 month.
Exclusion standard:1. pregnant, preparation gestation or women breast-feeding their children;2. to traditional Chinese medicine ingredients allergy sufferers;3. do not take in nearly 2 weeks Cross steroid medicine;Retinoid medicine or topical steroid preparation are not taken in 1 week;4. suspect or truly have alcohol, medicine indiscriminate Use history person;5. the severe primary disease such as angiocarpy, the cerebrovascular, liver, kidney and hemopoietic system, mental patient are associated with;6. certainly Row exits or does not complete whole case observation and affect judgement person.All cases are in January, 2015 ~ 2016 year December the author doctor Institute Dermatology Outpatient Department patient totally 25, wherein man 10, female 15,18 ~ 65 years old age, average 45.2 years old, the course of disease 3 months ~ 16 Year, average 10.3.
1.2 treatment method
All patients sign before the treatment Informed Consent Form.Using external application Chinese medicine of the present invention, with 30 days as a course for the treatment of, continuously 1 ~ 2 course for the treatment of of treatment, period avoids pungent food the product of stimulation, and taboo is drunk.
Observation index and observational technique
Using psoriatic lesion area and severity index(PASI)Point system is treated forward and backward symptom improvement situation to patient and is entered Row scoring.Including record lesions of patients area, erythema degree, the change of plump, the furfur order of severity is infiltrated, and record patient's pain The change of pain degree.
Curative effect determinate standard
The curative effect of patient is evaluated by PASI standards of grading.Therapeutic index=(PASI after PASI total scores-treatment before treatment Total score)PASI total score × 100% before/treatment.
Clinical cure:Therapeutic index is more than 95%;
It is effective:Therapeutic index 60% ~ 95%;
Take a turn for the better:Therapeutic index 30% ~ 59%;
It is invalid:Therapeutic index is less than 30%;
Total effective rate=(Into the improvement example of the effective number of cases+entrance statistics of the clinical recovery number of cases+entrance statistics of statistics Number)/ enter number of cases × 100% for counting.
As a result
In the people for the treatment of group 25, fully recover 10 people, effective 11 people, and take a turn for the better 3 people, invalid 1 people, total effective rate 96.0%.
The present invention reaches the psoriatic effect for the treatment of by clearing heat and detoxicating, eliminating dampness, dispelling wind and arresting itching.Its is evident in efficacy, significantly Patient suffering is alleviated, recurrence rate is decreased obviously, improve the quality of life of patient;And its toxic and side effect is relatively small, disease People can feel at ease to take.The Chinese medicine of the present invention, good effect, instant effect has no side effect, and total effective rate is up to 96.0%.
The wherein coptis, golden cypress heat-clearing and damp-drying drug, bactericidal antiphlogistic;The root bark of shaggy-fruited dittany, the fruit of summer cypress, frutus cnidii cooling blood, expelling wind are antipruritic;Adder-wort, Kuh-seng clearing heat and cooling blood, removing toxic substances, carbuncle that disappears dissipating bind,;Sulphur detoxicating and destroying parasites, hygroscopic are antipruritic.
To prove that the present invention has good curative effect, 4 model cases are enumerated as follows:
1. Chen, male, 54 years old, general papule of whole body, constantly diffusion, and pole is itched, and a large amount of furfurs, whole body is dark red, breach.It is after diagnosing Erythrodermic psoriasis.Using this medicine, three course for the treatment of recoveries from illness, recurrence is had no within 21 months.
2. Zhang, female, 46 years old, psoriasis en plaques, four limbs back had, not multiple again using two courses for the treatment of recoveries from illness of this medicine Send out.
3. Zhang, female, 30 years old, suffer from running sore psoriasis, see arm, send out less with it, using two course for the treatment of recoveries from illness of this medicine, It is existing not recur within 2 years.
4. Korea Spro, female 54 years old, suffers from whole body psoriasis en plaques, more than 30 years obstinate, also have on head.Using this medicine three The individual course for the treatment of is cured substantially.

Claims (2)

1. one kind treats psoriatic external application Chinese medicine, it is characterised in that:The weight proportion of each raw material(Unit g)For:Coptis 3-6, Golden cypress 5-10, root bark of shaggy-fruited dittany 5-10, sulphur 5-10, fruit of summer cypress 10-20, frutus cnidii 10-20, kuh-seng 10-20, adder-wort 10-15.
2. Chinese medicine composition as claimed in claim 1, it is characterised in that:The weight proportion of each raw material(Unit g)For:The coptis 5, Golden cypress 5, the root bark of shaggy-fruited dittany 8, sulphur 10, the fruit of summer cypress 15, frutus cnidii 15, kuh-seng 15, adder-wort 12.
CN201710215741.5A 2017-04-04 2017-04-04 Externally-applied traditional Chinese medicine for treating psoriasis Pending CN106668269A (en)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108969682A (en) * 2018-10-27 2018-12-11 盘锦金禾医院 A kind of seedling medicine prescription that treating psoriasis and its preparation method and application method
CN109125385A (en) * 2017-06-19 2019-01-04 贾学华 The psoriasic Chinese medicine preparation of external curing
CN111973712A (en) * 2020-09-16 2020-11-24 北京同春堂中医医院(普通合伙) Traditional Chinese medicine bath composition for treating psoriasis, preparation method and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109125385A (en) * 2017-06-19 2019-01-04 贾学华 The psoriasic Chinese medicine preparation of external curing
CN108969682A (en) * 2018-10-27 2018-12-11 盘锦金禾医院 A kind of seedling medicine prescription that treating psoriasis and its preparation method and application method
CN111973712A (en) * 2020-09-16 2020-11-24 北京同春堂中医医院(普通合伙) Traditional Chinese medicine bath composition for treating psoriasis, preparation method and application thereof

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