CN106620267A

CN106620267A - Traditional Chinese medicine composition for treating chicken chlamydia diseases

Info

Publication number: CN106620267A
Application number: CN201611100344.5A
Authority: CN
Inventors: 张俊清; 张明
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-12-05
Filing date: 2016-12-05
Publication date: 2017-05-10

Abstract

The invention discloses a traditional Chinese medicine composition for treating chicken chlamydia diseases and belongs to the technical field of the traditional Chinese medicine. The traditional Chinese medicine composition disclosed by the invention is prepared from the following components in parts by weight: 5-30 parts of edulis, 5-25 parts of cottonrose hibiscus, 5-25 parts of scabiosa, 3-18 parts of commelina paludosa, 3-20 parts of humifuse euphorbia herb, 5-20 parts of folium isatidis, 3-20 parts of prepared burdock, 5-25 parts of myrobalan, 5-25 parts of smoked plum, 5-20 parts of pericarpium granati, 3-18 parts of adenophora stricta, 3-20 parts of scorched hawthorn fruit, 5-25 parts of honey-fried licorice root and 5-20 parts of platycodon grandiflorum. The traditional Chinese medicine composition has the characteristics of removing heat to cool blood, purging fire for removing toxin, relieving diarrhea with astringents and benefiting spleen and stomach. In a treating process, a modern inspection technique is adopted for verifying, the curative effect is accurate and the clinical application is free from any toxic and side effect.

Description

A kind of Chinese medicine composition for treating chicken chlamydiosis

Technical field

The invention belongs to technical field of Chinese veterinary medicine, in particular, belongs to a kind of Chinese traditional medicine composition for treating chicken chlamydiosis Thing.

Background technology

Chicken chlamydiosis, also known as psittacosis and ornithosis, is the infectious disease by caused by chlamydia psittaci in prior art, This disease can also be transmitted to the mankind through skin, the mucous membrane of respiratory tract, eye conjunctiva and damage, be a kind of infectious diseases common to human beings and animals.

The chicken chlamydiosis cause of disease：Pathogen is chlamydia psittaci, can infect various mammals, bird and the mankind.Clothing Substance be a class have uniqueness growth cycle, endotrophic prokaryotic microorganism, its form with growth cycle not Together, there are individuality and the class form of group two.

Chicken Chlamydia epidemiology：This disease has pathogenic to various poultry, but it is more to be fallen ill with poult, and the death rate is high, Ill domestic animal, fowl and band bacterium person are major source of infection, can discharge cause of disease by excrement, urine, breast and apoblema, environment are polluted, by digestion Road infects healthy animal, also can Jing respiratory tract infections.

Chicken chlamydiosis main symptom：Sick just stream nose liquid, intraocular have secretion, then go out asthma, now exhale difficulty, tracheal strips to send The sound of rumble Lu, serious diarrhea, row's yellow-white light stool, feed intake is reduced, feather is fluffy, day is gradually thin, eyelid swelled, viscous Conjunction, eye projection, have serosity and purulent secretion to flow out, and upper and lower aganoblepharon occurs in the later stage, causes the eyelid of closure outside Projection, so that the opacity of the cornea or blind, diseased chicken egg production, incubation rate can decline.

Chicken chlamydiosis is diagnosed：Tentative diagnosis can only be made according to clinical symptoms change, making a definite diagnosis need to carry out pathogen isolation Culture identification；Plate coating checking, the dyeing of Ji's nurse Sa, microscopy, to find the cause of disease；Serological testing, using complement fixation reaction or blood Clear neutralization test；It is separately cultured, takes 0.3 milliliter of pathological material of disease suspension and be inoculated in 6-7 days chick embryo yolk sacs of hatching, takes yolk bag smear Microscopy, to check elementary body；Indirect hemagglutination inhibition test.

Prior art treats chicken chlamydiosis, and mostly based on quadracycline, erythromycin, livestock and poultry apply quadracycline Fatal hepatotoxicity wind agitation may be caused, have stimulation to oesophagus, so strictly to grasp dosage in use, said medicine is to simple Choamydiae infection therapeutic effect substantially, control by chlamydia and salmonella, the mixed infection type disorders of Escherichia coli multi-cultur es Therapeutic effect has much room for improvement.

The content of the invention

The present invention gives a kind of Chinese traditional medicine composition for treating chicken chlamydiosis to efficiently solve above technical problem Thing.

A kind of Chinese medicine composition for treating chicken chlamydiosis of the present invention, it is characterised in that constitute by following weight portion：Mountain Arrowhead 5-30 parts, cotton rose 5-25 parts, blue potted flower 5-25 parts, big bud dayflower 3-18 parts, wolf's milk 3-20 parts, folium isatidis 5-20 Part, process great burdock achene 3-20 parts, myrobalan's 5-25 parts, dark plum 5-25 parts, granatum 5-20 parts, the root of straight ladybell 3-18 parts, charred FRUCTUS CRATAEGI 3-20 parts, Radix Glycyrrhizae (processed with honey) 5-25 parts, balloonflower root 5-20 parts.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 5 Part, 5 parts of cotton rose, blue 5 parts of potted flower, big 3 parts of dayflower of bud, 3 parts of wolf's milk, 5 parts of folium isatidis, process 3 parts of great burdock achene, 5 parts of myrobalan, 5 parts of dark plum, 5 parts of granatum, 3 parts of the root of straight ladybell, 3 parts of charred FRUCTUS CRATAEGI, 5 parts of Radix Glycyrrhizae (processed with honey), 5 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 30 Part, 25 parts of cotton rose, blue 25 parts of potted flower, big 18 parts of dayflower of bud, 20 parts of wolf's milk, 20 parts of folium isatidis, process 20 parts of great burdock achene, scold 25 parts of son, 25 parts of dark plum, 20 parts of granatum, 18 parts of the root of straight ladybell, 20 parts of charred FRUCTUS CRATAEGI, 25 parts of Radix Glycyrrhizae (processed with honey), 20 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 10 Part, 8 parts of cotton rose, blue 7 parts of potted flower, big 5 parts of dayflower of bud, 5 parts of wolf's milk, 7 parts of folium isatidis, process 5 parts of great burdock achene, 6 parts of myrobalan, 7 parts of dark plum, 7 parts of granatum, 5 parts of the root of straight ladybell, 6 parts of charred FRUCTUS CRATAEGI, 8 parts of Radix Glycyrrhizae (processed with honey), 8 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 14 Part, 11 parts of cotton rose, blue 9 parts of potted flower, big 7 parts of dayflower of bud, 7 parts of wolf's milk, 9 parts of folium isatidis, process 7 parts of great burdock achene, myrobalan 8 Part, 9 parts of dark plum, 9 parts of granatum, 7 parts of the root of straight ladybell, 8 parts of charred FRUCTUS CRATAEGI, 12 parts of Radix Glycyrrhizae (processed with honey), 10 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 18 Part, 14 parts of cotton rose, blue 12 parts of potted flower, big 9 parts of dayflower of bud, 10 parts of wolf's milk, 11 parts of folium isatidis, process 9 parts of great burdock achene, myrobalan 12 parts, 13 parts of dark plum, 11 parts of granatum, 9 parts of the root of straight ladybell, 10 parts of charred FRUCTUS CRATAEGI, 15 parts of Radix Glycyrrhizae (processed with honey), 12 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 21 Part, 16 parts of cotton rose, blue 15 parts of potted flower, big 11 parts of dayflower of bud, 13 parts of wolf's milk, 12 parts of folium isatidis, process 11 parts of great burdock achene, scold 14 parts of son, 16 parts of dark plum, 14 parts of granatum, 12 parts of the root of straight ladybell, 13 parts of charred FRUCTUS CRATAEGI, 18 parts of Radix Glycyrrhizae (processed with honey), 14 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 24 Part, 18 parts of cotton rose, blue 17 parts of potted flower, big 13 parts of dayflower of bud, 15 parts of wolf's milk, 14 parts of folium isatidis, process 13 parts of great burdock achene, scold 16 parts of son, 19 parts of dark plum, 16 parts of granatum, 14 parts of the root of straight ladybell, 15 parts of charred FRUCTUS CRATAEGI, 21 parts of Radix Glycyrrhizae (processed with honey), 16 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 27 Part, 21 parts of cotton rose, blue 20 parts of potted flower, big 15 parts of dayflower of bud, 17 parts of wolf's milk, 16 parts of folium isatidis, process 16 parts of great burdock achene, scold 19 parts of son, 21 parts of dark plum, 17 parts of granatum, 15 parts of the root of straight ladybell, 17 parts of charred FRUCTUS CRATAEGI, 23 parts of Radix Glycyrrhizae (processed with honey), 17 parts of balloonflower root.

The Chinese medicine composition of chicken chlamydiosis is treated in accordance with the above, it is preferable that constituted by following weight portion：Edible tulip 28 Part, 23 parts of cotton rose, blue 22 parts of potted flower, big 17 parts of dayflower of bud, 18 parts of wolf's milk, 18 parts of folium isatidis, process 18 parts of great burdock achene, scold 22 parts of son, 23 parts of dark plum, 18 parts of granatum, 17 parts of the root of straight ladybell, 18 parts of charred FRUCTUS CRATAEGI, 24 parts of Radix Glycyrrhizae (processed with honey), 19 parts of balloonflower root.

Effect of each component in the Chinese medicine composition of the treatment chicken chlamydiosis of the present invention：

Edible tulip：Nature and flavor：It is sweet, micro-pungent, cold.Return through：Return liver, the spleen channel.Effect：Clearing heat and detoxicating, mass dissipating and swelling eliminating.Cure mainly：Carbuncle Subcutaneous ulcer serious case of furuncle, scrofula subcutaneous nodule, abscess of throat, toxic-heat and blood stasis, Chuan Yellow pyogenic infections, venomous snake bite.

Cotton rose：Nature and flavor：It is pungent, flat.Return through：Attach to the lung and stomach meridians.Effect：Removing pattogenic heat from the blood and toxic material from the body, detumescence toxin expelling, blood stasis removing analgesic.It is main Control：Red eye, swell pain, aphthae.

Blue potted flower：Nature and flavor：It is sweet, puckery, cool.Return through：Return liver, lung channel.Effect：Clearing heat-fire.Cure mainly：Irascibility stop up contain, heating, Cough with lung heat, jaundice.

Big bud dayflower：Nature and flavor：It is sweet, light, cold.Return through：The thoughts of returning home, liver, spleen, large intestine channel.Effect：Inducing diuresis for removing edema, heat-clearing solution Poison, cooling blood and hemostasis.Cure mainly：Abscess of throat, ulcerative carbuncle serious case of furuncle.

Wolf's milk：Nature and flavor：It is pungent, flat.Return through：Return liver, stomach, bladder warp.Effect：Clearing heat and promoting diuresis, removing pattogenic heat from the blood and toxic material from the body.Cure mainly：Carbuncle Subcutaneous ulcer sore, sore Huang pyogenic infections.

Folium isatidis：Nature and flavor：It is bitter, cold.Return through：The thoughts of returning home, stomach, lung channel.Effect：Clearing heat and detoxicating, cool blood.Cure mainly：For heat toxin On disturb cause sore Huang pyogenic infections, abscess of throat.

Process great burdock achene：Nature and flavor：Bitter, acrid, cold.Return through：Attach to the lung and stomach meridians.Effect：Dispelling wind and heat from the body, removing toxicity for detumescence, deliver Rash.Cure mainly；Wind-heat affecting lung, on disturb throat abscess of throat, sore Huang pyogenic infections, acne rash from the beginning of, constipation, wind fire pathogen it is it is dizzy, Red swollen, the heat toxin toothache of head wind toxin, gingivitis, carbuncle subcutaneous ulcer evil sore, mumps erysipelas are controlled in Hiccough and deaf, blurred vision, external application.

Myrobalan：Nature and flavor：Bitter, sour, puckery, temperature.Return through：Return lung, stomach, large intestine channel.Effect relieving diarrhea with astringents, astringe the lung to stop cough.Cure mainly： Rush down for the cold of insufficiency type, endless diarrhea, chronic cough are more than, the card of internal lesion caused by overexertion asthma.

Dark plum：Nature and flavor：Sour, puckery, temperature.Return through：Return liver, spleen, lung, large intestine channel.Effect：Astringe the lung puckery intestines, relieving diarrhea with astringents, promote the production of body fluid Quench the thirst.Cure mainly：For chronic cough to be more than, chronic diarrhea, protracted dysentery.

Granatum：Nature and flavor：Sour, puckery, temperature.Return through：Return lung, large intestine, kidney channel.Effect：Relieving diarrhea with astringents.Cure mainly：For chronic diarrhea Incessantly, splenasthenic diarrhea, cold intestines rush down.

The root of straight ladybell：Nature and flavor：Sweet, slight bitter.Return through：Attach to the lung and stomach meridians.Effect：Clearing heat and nourishing yin, beneficial spleen stomach invigorating, nourishing YIN for benefiting the kidney.It is main Control：Deficient fever, impairment of yin cough caused by dryness, thirsty and dry pharynx.

Charred FRUCTUS CRATAEGI：Nature and flavor：Sour, sweet, tepor.Return through：Return Pi, stomach, Liver Channel.Effect：Food digesting stomach fortifying, promoting blood circulation and removing blood stasis, convergence Only dysentery.Cure mainly：Meat product phlegm and retained fluid, feeling of fullness acid regurgitation, rush down dysentery intestines wind, pain in the back hernia.

Radix Glycyrrhizae (processed with honey)：Nature and flavor：It is flat, sweet.Return through：Return 12 warps.Effect：Tonifying Qi and in, relax the property of medicine, emergency analgesic therapy, solution The work(of poison.Cure mainly：Weakness of the spleen and the stomach, expelling phlegm and arresting coughing.Radix Glycyrrhizae (processed with honey) enhancing moistens the lung and relieve the cough, tonifying middle-Jiao and Qi effect, each medicine in mitigation side The property of medicine, lowers toxic and side effect.

Balloonflower root：Nature and flavor：It is bitter, pungent, flat.Return through：Return lung Jing.Effect：Ventilating the lung and resolving phlegm, profit swallows apocenosis.Cure mainly：The pungent scattered hardship of this product Let out, a surname opens lung qi, resolving sputum profit gas, and no matter fever and chills all can be applied, and treatment exopathogen violates lung, can sharp lung qi, the dense phlegm to arrange swelling lung.

The principle of reatment of the present invention：Clearing heat and cooling blood, purging intense heat and detonicating, relieving diarrhea with astringents, beneficial spleen stomach invigorating.

Fang Xie：With edible tulip, cotton rose, blue potted flower as main ingredient in side, clearing away heat,cooling blood and removing toxin cures mainly heat symptoms caused by an exopathgen and stops up caused by containing Cough, asthma, toxic-heat and blood stasis, the scattered stasis of heat in removing summer-heat；With big bud Commeline communis, wolf's milk, folium isatidis, great burdock achene is processed as adjuvant, Main ingredient fever, detoxicating and treating irascibility is assisted to stop up the work(that Sheng, cough with lung heat have the damp and hot cool blood in Qinghua concurrently；With myrobalan, dark plum, granatum, The root of straight ladybell, charred FRUCTUS CRATAEGI are adjutant, assist major-minor two medicines clearing heat and nourishing yin, beneficial spleen stomach invigorating, with its sour, puckery, Wen Zhixing, control diarrhoea with puckery The work(of intestines antidiarrheal；With balloonflower root as drugs rendering other drugs to act on the upper-jiao, medicine-carried it is up enter lung, opening lung-energy, removing toxic substances profit pharynx, lung qi a surname general rule cough only phlegm Disappear, liver wind-heat ceases then red eye, swell pain, photophobia is shed tears only.More than each medicine close and with solution epidemic disease poison train simultaneously and fill blood, adopting both clearing heat method and tonification method, Treat both principal and secondary aspect of disease and cure chicken chlamydiosis.

The beneficial effect of the present invention and prior art：The Chinese medicine composition of the present invention is overcome in prior art, and medicine is controlled Treatment acts on single deficiency, there is provided one kind treat because pure choamydiae infection and mixed type infection Salmonella, Escherichia coli The Traditional Chinese medicine composition formula of the chicken chlamydiosis that pathogen causes.

It is to change beast that the Chinese medicine composition of the present invention treats chicken chlamydiosis using the maximum difference of Western medicine with prior art The outdated ideas of doctor's clinically medication, due to Long-Time Service Western medicine medicine, medicine is in carcass after being absorbed and is remained, and endangers food Safety, threatens to human health, uses Western medicine medicine in treatment less, uses Chinese medicine preparation instead.Because many Chinese medicine preparations all have There is anti-inflammation, the function of enhance immunity can substitute the effect of Western medicine medicine, and medicine can be divided completely in animal body Solution and absorption, excreta environmentally safe is safe and reliable.

With treatment by Chinese herbs chicken chlamydiosis mixed infection salmonella, Escherichia coli, had the advantage that, one, this combination Thing can be directed to pure choamydiae infection, again can be to mixed infection type, and pathogen is mycoplasma and salmonella, large intestine bar The various cause of disease morbidities of bacterium have killing action；2nd, what is taken due to Chinese medicine is personalized compound preparation, and to illness pin is had more To property, due to the diversification of Effective Component of Chinese Medicine in therapeutic process, Chlamydia, salmonella, Escherichia coli are difficult to produce it Drug resistance so that Chinese medicine is treating this disease with obvious advantage.

Spice medicine source selected by the Chinese medicine composition of the present invention is easy to get, low cost.According to Ju theory of traditional Chinese medical science scientific compatibility, remain The combined effect of Chinese medicinal formulae tradition diagnosis and treatment based on an overall analysis of the illness and the patient's condition.Prepare it is simple, be easy to store and use, use manpower and material resources sparingly and easily cultivated Family receives.

The present invention combines over the course for the treatment of modern inspection technology and is verified, determined curative effect, and clinical practice is without any poison Side effect, suitable wide popularization and application.

Specific embodiment

Preferred embodiment 1

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 5 Part, 5 parts of cotton rose, blue 5 parts of potted flower, big 3 parts of dayflower of bud, 3 parts of wolf's milk, 5 parts of folium isatidis, process 3 parts of great burdock achene, 5 parts of myrobalan, 5 parts of dark plum, 5 parts of granatum, 3 parts of the root of straight ladybell, 3 parts of charred FRUCTUS CRATAEGI, 5 parts of Radix Glycyrrhizae (processed with honey), 5 parts of balloonflower root.

Preparation method one

Step one, immersion：By 5 parts of edible tulip, 5 parts of cotton rose, blue 5 parts of potted flower, big 3 parts of dayflower of bud, 3 parts of wolf's milk, 5 parts of folium isatidis, process 3 parts of great burdock achene, 5 parts of myrobalan, 5 parts of dark plum, 5 parts of granatum, 3 parts of the root of straight ladybell, 3 parts of charred FRUCTUS CRATAEGI, Radix Glycyrrhizae (processed with honey) 5 Part, 5 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 parts of purified waters, 40-50 DEG C immersion 1h, medicinal material is fully expanded；

Step 2, alcohol precipitation：Using decocting method twice, by medicinal material and purified water in step one, controlling steam pressure is 0.1-0.2MPa, after being heated to boiling, continues to boil 2h；

Fried liquid is taken out in step 3, separation, continues the purified water that 4 parts are added into medicinal material, controls steam pressure for 0.1- 0.2MPa, after being heated to boiling, continues to boil 1.5h, merges fried liquid twice and is extract；

Step 4, concentration：Obtained extract is added and is concentrated in economic benefits and social benefits concentration tank, steam pressure concentrated in vacuo is 0.1MPa, an effect vacuum concentrator operating pressure is 0.04MPa, and temperature is 80 DEG C；Two effect inspissator operating pressures 0.06MPa, Temperature is 65 DEG C, and concentration time is 2.5-3.5h, when heat survey relative density is 1.17-1.20, obtains concentrate；

Step 5, alcohol precipitation：Concentrate is placed in Alcohol-settling tank, 95% ethanol is slowly added to in Alcohol-settling tank, contain ethanol Measure as 65%-70%, stir 30min, 4 DEG C of refrigerations stand 48h, be evaporated to relative density for 1.40-1.50, reclaim second Alcohol, that is, obtain alcohol extracting liquid；

Step 6, with liquid：0.3-0.4 part purified waters are added in Agitation Tank, gained alcohol in step 4 is then sequentially added Extract, 0.003 part of Sodium Benzoate, stir to fully dissolving, the amount for adding purified water to be settled to 1 part, stir 15min, system Obtain the oral liquid of chicken chlamydiosis.

Preparation method two

Step one, by 5 parts of edible tulip, 5 parts of cotton rose, blue 5 parts of potted flower, big 3 parts of dayflower of bud, 3 parts of wolf's milk, folium isatidis 5 parts, process 3 parts of great burdock achene, 5 parts of myrobalan, 5 parts of dark plum, 5 parts of granatum, 3 parts of the root of straight ladybell, 3 parts of charred FRUCTUS CRATAEGI, 5 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 5 Part, it is well mixed, every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, and add water for the first time 5 times of weight, is decocted 3 hours；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Step 3, by decoction liquor filter obtain filtrate, filtrate be concentrated into relative density be 1.7-1.9 clear cream；

Step 4, merge clear cream twice, plus appropriate amount of starch, mix, be dried, crush, plus appropriate amount of ethanol make particle, drying Obtain final product.

Preparation method three

Step one, by 5 parts of edible tulip, 5 parts of cotton rose, blue 5 parts of potted flower, big 3 parts of dayflower of bud, 3 parts of wolf's milk, folium isatidis 5 parts, process 3 parts of great burdock achene, 5 parts of myrobalan, 5 parts of dark plum, 5 parts of granatum, 3 parts of the root of straight ladybell, 3 parts of charred FRUCTUS CRATAEGI, 5 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 5 Part, it is well mixed, every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus the decocting of 10 times of weight boils 3 hours, second The decocting of secondary plus 7 times of weight is boiled 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate, is concentrated the filtrate to relative Density is the thick paste of 1.26-1.36 (50 DEG C), is spray-dried, and obtains dry extract；

Step 2, take dry extract and add and be well mixed after appropriate lactose, dry-pressing loads capsule and obtains final product capsule system into particle Agent.

The usage and dosage of the present embodiment Chinese medicine composition：1st, oral liquid, usage and dosage：By chicken body weight 2ml/kg dosage, often It 1 time, it is used in conjunction 5-10 days.2nd, granule, usage and dosage：By chicken body weight 3g/kg dosage, once a day, 5-10 days are used in conjunction.Or Chinese medicine preparation according to the present embodiment directly soaks Chinese medicine composition mixing, then carries out infusion and obtains traditional Chinese herbal decoction, according to The body weight of diseased chicken chooses appropriate decoction and directly diseased chicken is gavaged.

Preferred embodiment 2

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 30 Part, 25 parts of cotton rose, blue 25 parts of potted flower, big 18 parts of dayflower of bud, 20 parts of wolf's milk, 20 parts of folium isatidis, process 20 parts of great burdock achene, scold 25 parts of son, 25 parts of dark plum, 20 parts of granatum, 18 parts of the root of straight ladybell, 20 parts of charred FRUCTUS CRATAEGI, 25 parts of Radix Glycyrrhizae (processed with honey), 20 parts of balloonflower root.

Preparation method one

Step one, immersion：By 30 parts of edible tulip, 25 parts of cotton rose, blue 25 parts of potted flower, big 18 parts of dayflower of bud, wolf's milk 20 parts, 20 parts of folium isatidis, process 20 parts of great burdock achene, 25 parts of myrobalan, 25 parts of dark plum, 20 parts of granatum, 18 parts of the root of straight ladybell, charred FRUCTUS CRATAEGI 20 Part, 25 parts of Radix Glycyrrhizae (processed with honey), 20 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 Part purified water, 40-50 DEG C of immersion 1h, makes medicinal material fully expand；

Step 6, with liquid：0.3-0.4 part purified waters are added in Agitation Tank, gained alcohol in step 4 is then sequentially added Extract, 0.003 part of Sodium Benzoate, stir to fully dissolving, the amount for adding purified water to be settled to 1 part, stir 15min, system Obtain oral liquid formulations.

Preparation method two

Step one, by 30 parts of edible tulip, 25 parts of cotton rose, blue 25 parts of potted flower, big 18 parts of dayflower of bud, 20 parts of wolf's milk, 20 parts of folium isatidis, process 20 parts of great burdock achene, 25 parts of myrobalan, 25 parts of dark plum, 20 parts of granatum, 18 parts of the root of straight ladybell, 20 parts of charred FRUCTUS CRATAEGI, honey and process 25 parts of Radix Glycyrrhizae, 20 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds water for the first time 5 times Weight, decocts 3 hours；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

In step 4, clear cream plus appropriate amount of starch, mix, be dried, crush after plus appropriate amount of ethanol make particle, be drying to obtain Grain preparation.

Preparation method three

Step one, by 30 parts of edible tulip, 25 parts of cotton rose, blue 25 parts of potted flower, big 18 parts of dayflower of bud, 20 parts of wolf's milk, 20 parts of folium isatidis, process 20 parts of great burdock achene, 25 parts of myrobalan, 25 parts of dark plum, 20 parts of granatum, 18 parts of the root of straight ladybell, 20 parts of charred FRUCTUS CRATAEGI, honey and process 25 parts of Radix Glycyrrhizae, 20 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus 10 times of weight Decocting is boiled 3 hours, adds the decocting of 7 times of weight to boil for the second time 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate, The thick paste that relative density is 1.26-1.36 (50 DEG C) is concentrated the filtrate to, is spray-dried, obtain dry extract；

Preferred embodiment 3

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 10 Part, 8 parts of cotton rose, blue 7 parts of potted flower, big 5 parts of dayflower of bud, 5 parts of wolf's milk, 7 parts of folium isatidis, process 5 parts of great burdock achene, 6 parts of myrobalan, 7 parts of dark plum, 7 parts of granatum, 5 parts of the root of straight ladybell, 6 parts of charred FRUCTUS CRATAEGI, 8 parts of Radix Glycyrrhizae (processed with honey), 8 parts of balloonflower root.

Preparation method one

Step one, immersion：By 10 parts of edible tulip, 8 parts of cotton rose, blue 7 parts of potted flower, big 5 parts of dayflower of bud, 5 parts of wolf's milk, 7 parts of folium isatidis, process 5 parts of great burdock achene, 6 parts of myrobalan, 7 parts of dark plum, 7 parts of granatum, 5 parts of the root of straight ladybell, 6 parts of charred FRUCTUS CRATAEGI, Radix Glycyrrhizae (processed with honey) 8 Part, 8 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 parts of purified waters, 40-50 DEG C immersion 1h, medicinal material is fully expanded；

Preparation method two

Step one, by 10 parts of edible tulip, 8 parts of cotton rose, blue 7 parts of potted flower, big 5 parts of dayflower of bud, 5 parts of wolf's milk, smalt 7 parts of leaf, process 5 parts of great burdock achene, 6 parts of myrobalan, 7 parts of dark plum, 7 parts of granatum, 5 parts of the root of straight ladybell, 6 parts of charred FRUCTUS CRATAEGI, 8 parts of Radix Glycyrrhizae (processed with honey), tangerine 8 parts of stalk, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, and add water for the first time 5 times of weight, decocts 3 little When；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Preparation method three

Step one, by 10 parts of edible tulip, 8 parts of cotton rose, blue 7 parts of potted flower, big 5 parts of dayflower of bud, 5 parts of wolf's milk, smalt 7 parts of leaf, process 5 parts of great burdock achene, 6 parts of myrobalan, 7 parts of dark plum, 7 parts of granatum, 5 parts of the root of straight ladybell, 6 parts of charred FRUCTUS CRATAEGI, 8 parts of Radix Glycyrrhizae (processed with honey), tangerine 8 parts of stalk, is well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus the decocting of 10 times of weight is boiled 3 hours, Add for second the decocting of 7 times of weight to boil 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate is concentrated the filtrate to Relative density is the thick paste of 1.26-1.36 (50 DEG C), is spray-dried, and obtains dry extract；

Preferred embodiment 4

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 14 Part, 11 parts of cotton rose, blue 9 parts of potted flower, big 7 parts of dayflower of bud, 7 parts of wolf's milk, 9 parts of folium isatidis, process 7 parts of great burdock achene, myrobalan 8 Part, 9 parts of dark plum, 9 parts of granatum, 7 parts of the root of straight ladybell, 8 parts of charred FRUCTUS CRATAEGI, 12 parts of Radix Glycyrrhizae (processed with honey), 10 parts of balloonflower root.

Preparation method one

Step one, immersion：By 14 parts of edible tulip, 11 parts of cotton rose, blue 9 parts of potted flower, big 7 parts of dayflower of bud, wolf's milk 7 Part, 9 parts of folium isatidis, process 7 parts of great burdock achene, 8 parts of myrobalan, 9 parts of dark plum, 9 parts of granatum, 7 parts of the root of straight ladybell, 8 parts of charred FRUCTUS CRATAEGI, Radix Glycyrrhizae (processed with honey) 12 parts, 10 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 parts of purified waters, 40- 50 DEG C of immersion 1h, make medicinal material fully expand；

Preparation method two

Step one, by 14 parts of edible tulip, 11 parts of cotton rose, blue 9 parts of potted flower, big 7 parts of dayflower of bud, 7 parts of wolf's milk, smalt 9 parts of leaf, process 7 parts of great burdock achene, 8 parts of myrobalan, 9 parts of dark plum, 9 parts of granatum, 7 parts of the root of straight ladybell, 8 parts of charred FRUCTUS CRATAEGI, 12 parts of Radix Glycyrrhizae (processed with honey), tangerine 10 parts of stalk, is well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, and add water for the first time 5 times of weight, decocts 3 Hour；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Preparation method three

Step one, by 14 parts of edible tulip, 11 parts of cotton rose, blue 9 parts of potted flower, big 7 parts of dayflower of bud, 7 parts of wolf's milk, smalt 9 parts of leaf, process 7 parts of great burdock achene, 8 parts of myrobalan, 9 parts of dark plum, 9 parts of granatum, 7 parts of the root of straight ladybell, 8 parts of charred FRUCTUS CRATAEGI, 12 parts of Radix Glycyrrhizae (processed with honey), tangerine 10 parts of stalk, is well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus the decocting of 10 times of weight is boiled 3 hours, Add for second the decocting of 7 times of weight to boil 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate is concentrated the filtrate to Relative density is the thick paste of 1.26-1.36 (50 DEG C), is spray-dried, and obtains dry extract；

Preferred embodiment 5

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 18 Part, 14 parts of cotton rose, blue 12 parts of potted flower, big 9 parts of dayflower of bud, 10 parts of wolf's milk, 11 parts of folium isatidis, process 9 parts of great burdock achene, myrobalan 12 parts, 13 parts of dark plum, 11 parts of granatum, 9 parts of the root of straight ladybell, 10 parts of charred FRUCTUS CRATAEGI, 15 parts of Radix Glycyrrhizae (processed with honey), 12 parts of balloonflower root.

Preparation method one

Step one, immersion：By 18 parts of edible tulip, 14 parts of cotton rose, blue 12 parts of potted flower, big 9 parts of dayflower of bud, wolf's milk 10 Part, 11 parts of folium isatidis, process 9 parts of great burdock achene, 12 parts of myrobalan, 13 parts of dark plum, 11 parts of granatum, 9 parts of the root of straight ladybell, 10 parts of charred FRUCTUS CRATAEGI, honey 15 parts of honey-fried licorice root, 12 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 parts of purifying Water, 40-50 DEG C of immersion 1h, makes medicinal material fully expand；

Preparation method two

Step one, by 18 parts of edible tulip, 14 parts of cotton rose, blue 12 parts of potted flower, big 9 parts of dayflower of bud, 10 parts of wolf's milk, big 11 parts of leafiness, process 9 parts of great burdock achene, 12 parts of myrobalan, 13 parts of dark plum, 11 parts of granatum, 9 parts of the root of straight ladybell, 10 parts of charred FRUCTUS CRATAEGI, Radix Glycyrrhizae (processed with honey) 15 parts, 12 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, and add water for the first time 5 times of weights Amount, decocts 3 hours；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Preparation method three

Step one, by 18 parts of edible tulip, 14 parts of cotton rose, blue 12 parts of potted flower, big 9 parts of dayflower of bud, 10 parts of wolf's milk, big 11 parts of leafiness, process 9 parts of great burdock achene, 12 parts of myrobalan, 13 parts of dark plum, 11 parts of granatum, 9 parts of the root of straight ladybell, 10 parts of charred FRUCTUS CRATAEGI, Radix Glycyrrhizae (processed with honey) 15 parts, 12 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus the decocting of 10 times of weight Boil 3 hours, add the decocting of 7 times of weight to boil for the second time 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate will be filtered Liquid is concentrated into the thick paste that relative density is 1.26-1.36 (50 DEG C), is spray-dried, and obtains dry extract；

Preferred embodiment 6

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 21 Part, 16 parts of cotton rose, blue 15 parts of potted flower, big 11 parts of dayflower of bud, 13 parts of wolf's milk, 12 parts of folium isatidis, process 11 parts of great burdock achene, scold 14 parts of son, 16 parts of dark plum, 14 parts of granatum, 12 parts of the root of straight ladybell, 13 parts of charred FRUCTUS CRATAEGI, 18 parts of Radix Glycyrrhizae (processed with honey), 14 parts of balloonflower root.

Preparation method one

Step one, immersion：By 21 parts of edible tulip, 16 parts of cotton rose, blue 15 parts of potted flower, big 11 parts of dayflower of bud, wolf's milk 13 parts, 12 parts of folium isatidis, process 11 parts of great burdock achene, 14 parts of myrobalan, 16 parts of dark plum, 14 parts of granatum, 12 parts of the root of straight ladybell, charred FRUCTUS CRATAEGI 13 Part, 18 parts of Radix Glycyrrhizae (processed with honey), 14 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 Part purified water, 40-50 DEG C of immersion 1h, makes medicinal material fully expand；

Preparation method two

Step one, by 21 parts of edible tulip, 16 parts of cotton rose, blue 15 parts of potted flower, big 11 parts of dayflower of bud, 13 parts of wolf's milk, 12 parts of folium isatidis, process 11 parts of great burdock achene, 14 parts of myrobalan, 16 parts of dark plum, 14 parts of granatum, 12 parts of the root of straight ladybell, 13 parts of charred FRUCTUS CRATAEGI, honey and process 18 parts of Radix Glycyrrhizae, 14 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds water for the first time 5 times Weight, decocts 3 hours；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Preparation method three

Step one, by 21 parts of edible tulip, 16 parts of cotton rose, blue 15 parts of potted flower, big 11 parts of dayflower of bud, 13 parts of wolf's milk, 12 parts of folium isatidis, process 11 parts of great burdock achene, 14 parts of myrobalan, 16 parts of dark plum, 14 parts of granatum, 12 parts of the root of straight ladybell, 13 parts of charred FRUCTUS CRATAEGI, honey and process 18 parts of Radix Glycyrrhizae, 14 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus 10 times of weight Decocting is boiled 3 hours, adds the decocting of 7 times of weight to boil for the second time 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate, The thick paste that relative density is 1.26-1.36 (50 DEG C) is concentrated the filtrate to, is spray-dried, obtain dry extract；

Preferred embodiment 7

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 24 Part, 18 parts of cotton rose, blue 17 parts of potted flower, big 13 parts of dayflower of bud, 15 parts of wolf's milk, 14 parts of folium isatidis, process 13 parts of great burdock achene, scold 16 parts of son, 19 parts of dark plum, 16 parts of granatum, 14 parts of the root of straight ladybell, 15 parts of charred FRUCTUS CRATAEGI, 21 parts of Radix Glycyrrhizae (processed with honey), 16 parts of balloonflower root.

Preparation method one

Step one, immersion：By 24 parts of edible tulip, 18 parts of cotton rose, blue 17 parts of potted flower, big 13 parts of dayflower of bud, wolf's milk 15 parts, 14 parts of folium isatidis, process 13 parts of great burdock achene, 16 parts of myrobalan, 19 parts of dark plum, 16 parts of granatum, 14 parts of the root of straight ladybell, charred FRUCTUS CRATAEGI 15 Part, 21 parts of Radix Glycyrrhizae (processed with honey), 16 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 Part purified water, 40-50 DEG C of immersion 1h, makes medicinal material fully expand；

Preparation method two

Step one, by 24 parts of edible tulip, 18 parts of cotton rose, blue 17 parts of potted flower, big 13 parts of dayflower of bud, 15 parts of wolf's milk, 14 parts of folium isatidis, process 13 parts of great burdock achene, 16 parts of myrobalan, 19 parts of dark plum, 16 parts of granatum, 14 parts of the root of straight ladybell, 15 parts of charred FRUCTUS CRATAEGI, honey and process 21 parts of Radix Glycyrrhizae, 16 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds water for the first time 5 times Weight, decocts 3 hours；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Preparation method three

Step one, by 24 parts of edible tulip, 18 parts of cotton rose, blue 17 parts of potted flower, big 13 parts of dayflower of bud, 15 parts of wolf's milk, 14 parts of folium isatidis, process 13 parts of great burdock achene, 16 parts of myrobalan, 19 parts of dark plum, 16 parts of granatum, 14 parts of the root of straight ladybell, 15 parts of charred FRUCTUS CRATAEGI, honey and process 21 parts of Radix Glycyrrhizae, 16 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus 10 times of weight Decocting is boiled 3 hours, adds the decocting of 7 times of weight to boil for the second time 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate, The thick paste that relative density is 1.26-1.36 (50 DEG C) is concentrated the filtrate to, is spray-dried, obtain dry extract；

Preferred embodiment 8

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 27 Part, 21 parts of cotton rose, blue 20 parts of potted flower, big 15 parts of dayflower of bud, 17 parts of wolf's milk, 16 parts of folium isatidis, process 16 parts of great burdock achene, scold 19 parts of son, 21 parts of dark plum, 17 parts of granatum, 15 parts of the root of straight ladybell, 17 parts of charred FRUCTUS CRATAEGI, 23 parts of Radix Glycyrrhizae (processed with honey), 17 parts of balloonflower root.

Preparation method one

Step one, immersion：By 27 parts of edible tulip, 21 parts of cotton rose, blue 20 parts of potted flower, big 15 parts of dayflower of bud, wolf's milk 17 parts, 16 parts of folium isatidis, process 16 parts of great burdock achene, 19 parts of myrobalan, 21 parts of dark plum, 17 parts of granatum, 15 parts of the root of straight ladybell, charred FRUCTUS CRATAEGI 17 Part, 23 parts of Radix Glycyrrhizae (processed with honey), 17 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 Part purified water, 40-50 DEG C of immersion 1h, makes medicinal material fully expand；

Preparation method two

Step one, by 27 parts of edible tulip, 21 parts of cotton rose, blue 20 parts of potted flower, big 15 parts of dayflower of bud, 17 parts of wolf's milk, 16 parts of folium isatidis, process 16 parts of great burdock achene, 19 parts of myrobalan, 21 parts of dark plum, 17 parts of granatum, 15 parts of the root of straight ladybell, 17 parts of charred FRUCTUS CRATAEGI, honey and process 23 parts of Radix Glycyrrhizae, 17 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds water for the first time 5 times Weight, decocts 3 hours；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Preparation method three

Step one, by 27 parts of edible tulip, 21 parts of cotton rose, blue 20 parts of potted flower, big 15 parts of dayflower of bud, 17 parts of wolf's milk, 16 parts of folium isatidis, process 16 parts of great burdock achene, 19 parts of myrobalan, 21 parts of dark plum, 17 parts of granatum, 15 parts of the root of straight ladybell, 17 parts of charred FRUCTUS CRATAEGI, honey and process 23 parts of Radix Glycyrrhizae, 17 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus 10 times of weight Decocting is boiled 3 hours, adds the decocting of 7 times of weight to boil for the second time 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate, The thick paste that relative density is 1.26-1.36 (50 DEG C) is concentrated the filtrate to, is spray-dried, obtain dry extract；

Preferred embodiment 9

The Chinese medicine composition of the treatment chicken chlamydiosis of this specific embodiment, is constituted by following weight portion：Edible tulip 28 Part, 23 parts of cotton rose, blue 22 parts of potted flower, big 17 parts of dayflower of bud, 18 parts of wolf's milk, 18 parts of folium isatidis, process 18 parts of great burdock achene, scold 22 parts of son, 23 parts of dark plum, 18 parts of granatum, 17 parts of the root of straight ladybell, 18 parts of charred FRUCTUS CRATAEGI, 24 parts of Radix Glycyrrhizae (processed with honey), 19 parts of balloonflower root.

Preparation method one

Step one, immersion：By 28 parts of edible tulip, 23 parts of cotton rose, blue 22 parts of potted flower, big 17 parts of dayflower of bud, wolf's milk 18 parts, 18 parts of folium isatidis, process 18 parts of great burdock achene, 22 parts of myrobalan, 23 parts of dark plum, 18 parts of granatum, 17 parts of the root of straight ladybell, charred FRUCTUS CRATAEGI 18 Part, 24 parts of Radix Glycyrrhizae (processed with honey), 19 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds 6 Part purified water, 40-50 DEG C of immersion 1h, makes medicinal material fully expand；

Preparation method two

Step one, by 28 parts of edible tulip, 23 parts of cotton rose, blue 22 parts of potted flower, big 17 parts of dayflower of bud, 18 parts of wolf's milk, 18 parts of folium isatidis, process 18 parts of great burdock achene, 22 parts of myrobalan, 23 parts of dark plum, 18 parts of granatum, 17 parts of the root of straight ladybell, 18 parts of charred FRUCTUS CRATAEGI, honey and process 24 parts of Radix Glycyrrhizae, 19 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and medicine gross weight is designated as 1 part, adds water for the first time 5 times Weight, decocts 3 hours；

Step 2, add water for the 2nd time 2 times of weight, decocts 1 hour；

Preparation method three

Step one, by 28 parts of edible tulip, 23 parts of cotton rose, blue 22 parts of potted flower, big 17 parts of dayflower of bud, 18 parts of wolf's milk, 18 parts of folium isatidis, process 18 parts of great burdock achene, 22 parts of myrobalan, 23 parts of dark plum, 18 parts of granatum, 17 parts of the root of straight ladybell, 18 parts of charred FRUCTUS CRATAEGI, honey and process 24 parts of Radix Glycyrrhizae, 19 parts of balloonflower root, are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 part, plus 10 times of weight Decocting is boiled 3 hours, adds the decocting of 7 times of weight to boil for the second time 2 hours, decoction liquor will be filtered with 3 layers of gauze twice, merging filtrate, The thick paste that relative density is 1.26-1.36 (50 DEG C) is concentrated the filtrate to, is spray-dried, obtain dry extract；

Concrete test

Trial drug：This composition medicine is respectively adopted, combination prepared by the preferred embodiment for the present invention 1,2,3,4,5,6 Thing oral liquid, 7 groups is randomly divided into diseased chicken and is treated respectively and is compareed with last group, by chicken body weight 2ml/kg agent Amount, is drawn after medicine with 10ml syringes, is grasped the direct Jing diseased chickens oral cavity of dosage and is slowly injected into, and once a day, is used in conjunction 6 days；

Test method：1st, gather diseased chicken whole blood before medication to separate after serum, Jing laboratories complement fixation reaction testing inspection, It is diagnosed as chlamydiosis.2nd, after this composition group medication 8 days, collection diseased chicken whole blood separates serum, and Jing laboratories complement combines anti- Reinspection should be tested, pharmacodynamic results are observed, and is recorded.3rd, blank control group is observed diseased chicken and is faced not use drug therapy group Bed symptom change, the cut open inspection part diseased chicken after 8 days, each organ pathological change of observation internal organ, and record.

1 composition test group of table is contrasted with blank control group

Group	Treatment number of cases	Cure number of cases	Effective number of cases	Invalid number of cases
					1 group of this composition	17	14	15	2
2 groups of this composition	15	13	14	1
					3 groups of this composition	14	12	13	1
4 groups of this composition	15	14	14	1
					5 groups of this composition	16	14	15	1
6 groups of this composition	18	16	17	1
					Blank control group	17	0	0	17

Blank control group is sick not use drug therapy group, control group diseased chicken clinical symptoms to be showed no any improvement Just stream nose liquid, intraocular have secretion, then go out asthma, now exhale difficulty, tracheal strips to send the sound of rumble Lu, serious diarrhea, row Yellow-white light stool, feed intake is reduced, feather is fluffy, day is gradually thin, and eyelid swelled, bonding, eye projection have serosity and purulence Sexual secretion flows out, and upper and lower aganoblepharon occurs in the later stage, the eyelid outwardly convex of closure is caused, under diseased chicken feeding and egg production Drop, blank control group observes dead 3 diseased chickens in 8 days, dead diseased chicken cut open inspection change：Diseased chicken liver enlargement, serious congested, essence Property disperse have a syringe needle size necrosis region, spleen exception enlargement has fibrinous exudate on abdominal cavity serosal surface and mesenterium, Intestinal mucosa is congested, bleeding.

Curative effect determinate standard：Criterion of cure：Diseased chicken diarrhea, gong sound absent respiration, eyelid enlargement, conjunctiva thicken, up and down Aganoblepharon symptom disappears.Effective standard：Diseased chicken diarrhea, gong sound breath sound goes down, and eyelid enlargement, conjunctiva are thickened, upper palpebra inferior Adhesion symptom has no change.Null criterion：Clinical symptoms have no any change.

Trial drug：This composition test group medicine is adopted, composition oral prepared by the preferred embodiment for the present invention 2 Liquid, by diseased chicken body weight 2ml/kg dosage, is drawn after medicine with 10ml syringes, is grasped the direct Jing chickens oral cavity of dial-adose and is slowly noted Enter, once a day, be used in conjunction 6 days.

Control group selects ROX (commercially available prod, ROX pulvis)；Usage and dosage：By diseased chicken body weight 1.5g/kg Dosage, is diluted with water for injection 5ml, with 10 milliliters of syringes, is grasped dial-adose direct oral cavity and is slowly dropped into, and once a day, is used in conjunction 6 days.

Test method：1st, collection diseased chicken whole blood separation serum before medication, Jing laboratories complement fixation reaction testing inspection, really Examine as chlamydiosis, while other bacterial classifications in examination diseased chicken blood, detection salmonella, Escherichia coli, confirm this subinfection disease Substance is Chlamydia mixed infection type.2nd, after medication 6 days, collection test diseased chicken whole blood is separated after serum, Jing complement fixation reactions Test is rechecked, and salmonella and Escherichia coli in Screening tests diseased chicken blood.

2 composition groups of table are tested with control group

Experiment group	Morbidity number	Treatment number	Cure number	Effective number	Recurrence number
						This composition group	15	15	14	15	0
ROX	17	17	15	16	1

More in the majority in mixed infection because clinical bird infects chlamydiosis, chlamydia disease uses merely symptomatic treatment Medicine, therapeutic effect is not good, so special according to the clinical onset rule of bird chlamydiosis, and chlamydiosis mixed infection type Point, The present invention gives a kind of Chinese medicine composition for solving the above problems, Chinese medicine group of the invention as can be seen from the above tests Compound, to treating chicken chlamydiosis mixed infection salmonella, E. coli pathogens, having preferably suppress and killing action, The present invention is verified that determined curative effect, drug effect is safe and reliable with reference to modern inspection technology over the course for the treatment of, and clinical practice is without appointing What toxic and side effect.

Test medical record：Certain chicken farm poultry raiser reacts, and this has in the recent period part diseased chicken, stands transfixed to the ground, and spirit is depressed, breathing Quickening sends the sound that beats gongs, and has lasting diarrhea to show.

Clinical examination and diagnosis：Diseased chicken accelerated breathing tracheal strips have gong sound, and loose random, spirit is depressed, serious diarrhea row Yellow or white loose stool, eyelid enlargement, conjunctiva are thickened, shed tears, having serosity and purulent secretion to flow out, and upper and lower aganoblepharon is caused The eyelid outwardly convex of closure, collection diseased chicken whole blood is set to separate after serum, complement fixation reaction test in Jing laboratories is diagnosed as chicken Chlamydiosis.

Treatment：From this preferred embodiment 2 prepare oral liquid, to 56 diseased chickens press body weight 2ml/kg dosage, daily 1 It is secondary, it is used in conjunction 6 days；Most diseased chicken accelerated breathing after medication 4 days, tracheal strips gong sound disappears, and continues diarrhea symptom and substantially mitigates；With The diseased chicken accelerated breathing of medicine all medications after 6 days, tracheal strips gong sound symptom all disappears, and eyelid enlargement, conjunctiva thicken regression, eye Portion's serosity and purulent secretion disappear；Diseased chicken whole blood is gathered after medication 9 days and separates serum, Jing complement fixation test (CFT) detection methods, 53 feminine genders of testing result Chlamydia, 3 positives.

Claims

1. a kind of Chinese medicine composition for treating chicken chlamydiosis, it is characterised in that constitute by following weight portion：Edible tulip 5-30 Part, cotton rose 5-25 parts, blue potted flower 5-25 parts, big bud dayflower 3-18 parts, wolf's milk 3-20 parts, folium isatidis 5-20 parts, process ox Burdock 3-20 parts, myrobalan's 5-25 parts, dark plum 5-25 parts, granatum 5-20 parts, the root of straight ladybell 3-18 parts, charred FRUCTUS CRATAEGI 3-20 parts, honey are processed sweet Careless 5-25 parts, balloonflower root 5-20 parts.

2. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：5 parts of edible tulip, 5 parts of cotton rose, blue 5 parts of potted flower, big 3 parts of dayflower of bud, 3 parts of wolf's milk, 5 parts of folium isatidis, process great burdock achene 3 Part, 5 parts of myrobalan, 5 parts of dark plum, 5 parts of granatum, 3 parts of the root of straight ladybell, 3 parts of charred FRUCTUS CRATAEGI, 5 parts of Radix Glycyrrhizae (processed with honey), 5 parts of balloonflower root.

3. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：30 parts of edible tulip, 25 parts of cotton rose, blue 25 parts of potted flower, big 18 parts of dayflower of bud, 20 parts of wolf's milk, 20 parts of folium isatidis, process ox 20 parts of burdock, 25 parts of myrobalan, 25 parts of dark plum, 20 parts of granatum, 18 parts of the root of straight ladybell, 20 parts of charred FRUCTUS CRATAEGI, 25 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 20 Part.

4. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：10 parts of edible tulip, 8 parts of cotton rose, blue 7 parts of potted flower, big 5 parts of dayflower of bud, 5 parts of wolf's milk, 7 parts of folium isatidis, process great burdock achene 5 Part, 6 parts of myrobalan, 7 parts of dark plum, 7 parts of granatum, 5 parts of the root of straight ladybell, 6 parts of charred FRUCTUS CRATAEGI, 8 parts of Radix Glycyrrhizae (processed with honey), 8 parts of balloonflower root.

5. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：14 parts of edible tulip, 11 parts of cotton rose, blue 9 parts of potted flower, big 7 parts of dayflower of bud, 7 parts of wolf's milk, 9 parts of folium isatidis, process great burdock achene 7 parts, 8 parts of myrobalan, 9 parts of dark plum, 9 parts of granatum, 7 parts of the root of straight ladybell, 8 parts of charred FRUCTUS CRATAEGI, 12 parts of Radix Glycyrrhizae (processed with honey), 10 parts of balloonflower root.

6. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：18 parts of edible tulip, 14 parts of cotton rose, blue 12 parts of potted flower, big 9 parts of dayflower of bud, 10 parts of wolf's milk, 11 parts of folium isatidis, process ox 9 parts of burdock, 12 parts of myrobalan, 13 parts of dark plum, 11 parts of granatum, 9 parts of the root of straight ladybell, 10 parts of charred FRUCTUS CRATAEGI, 15 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 12 Part.

7. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：21 parts of edible tulip, 16 parts of cotton rose, blue 15 parts of potted flower, big 11 parts of dayflower of bud, 13 parts of wolf's milk, 12 parts of folium isatidis, process ox 11 parts of burdock, 14 parts of myrobalan, 16 parts of dark plum, 14 parts of granatum, 12 parts of the root of straight ladybell, 13 parts of charred FRUCTUS CRATAEGI, 18 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 14 Part.

8. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：24 parts of edible tulip, 18 parts of cotton rose, blue 17 parts of potted flower, big 13 parts of dayflower of bud, 15 parts of wolf's milk, 14 parts of folium isatidis, process ox 13 parts of burdock, 16 parts of myrobalan, 19 parts of dark plum, 16 parts of granatum, 14 parts of the root of straight ladybell, 15 parts of charred FRUCTUS CRATAEGI, 21 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 16 Part.

9. the chlamydial Chinese medicine composition of chicken is treated according to claim 1, it is characterised in that constituted by following weight portion： 27 parts of edible tulip, 21 parts of cotton rose, blue 20 parts of potted flower, big 15 parts of dayflower of bud, 17 parts of wolf's milk, 16 parts of folium isatidis, process burdock 16 parts of son, 19 parts of myrobalan, 21 parts of dark plum, 17 parts of granatum, 15 parts of the root of straight ladybell, 17 parts of charred FRUCTUS CRATAEGI, 23 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 17 Part.

10. the Chinese medicine composition of chicken chlamydiosis is treated according to claim 1, it is characterised in that by following weight portion group Into：28 parts of edible tulip, 23 parts of cotton rose, blue 22 parts of potted flower, big 17 parts of dayflower of bud, 18 parts of wolf's milk, 18 parts of folium isatidis, process ox 18 parts of burdock, 22 parts of myrobalan, 23 parts of dark plum, 18 parts of granatum, 17 parts of the root of straight ladybell, 18 parts of charred FRUCTUS CRATAEGI, 24 parts of Radix Glycyrrhizae (processed with honey), balloonflower root 19 Part.