CN106619980A - Pain removal plaster for treating arthralgia as well as preparation method and application of pain removal plaster - Google Patents
Pain removal plaster for treating arthralgia as well as preparation method and application of pain removal plaster Download PDFInfo
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- CN106619980A CN106619980A CN201710085389.8A CN201710085389A CN106619980A CN 106619980 A CN106619980 A CN 106619980A CN 201710085389 A CN201710085389 A CN 201710085389A CN 106619980 A CN106619980 A CN 106619980A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
The invention discloses a pain removal plaster for treating arthralgia as well as a preparation method and an application of the pain removal plaster. The pain removal plaster is prepared from the following raw materials in parts by weight: 15-25 parts of asiatic striga herb, 2-5 parts of tulostoma jourdanii pat, 11-19 parts of herb of lysimachia decurrens Forst.f., 1-3 parts of doxycycline hydrochloride and 3-7 parts of cicada slough. The preparation method comprises the following steps: crushing the tulostoma jourdanii pat and the cicada slough, filtering the crushed tulostoma jourdanii pat and cicada slough by virtue of a 60-mesh sieve, then soaking filtered powder in table vinegar for 3.5h, and roasting the powder at a temperature of 65 DEG C for 5h, so that mixed powder A is obtained; and crushing the asiatic striga herb and the herb of lysimachia decurrens Forst.f., then adding de-ionized water, decocting obtained powder for 3.3h, conducting filtering and reserving a filtrate, then concentrating the filtrate to 30% of an original volume, adding the mixed powder A, conducting stirring treatment at a temperature of 72 DEG C for 25min, then reducing the temperature to room temperature, adding the doxycycline hydrochloride, and uniformly mixing and stirring all materials, so that the pain removal plaster is obtained. The plaster provided by the invention, under mutual actions of the various raw materials, has an obvious curative effect on treating the arthralgia, and the plaster is short in treatment course, free from toxic and side effects and free from recurrence after recovery. Moreover, the preparation method provided by the invention is simple in preparation process, easy to operate, convenient to use and applicable to industrial production.
Description
Technical field
The present invention relates to pharmaceutical technology field, specifically one kind are treated arthralgic ache-reliving plaster medicine and preparation method thereof and are answered
With.
Background technology
Arthralgia causes mainly due to arthritis or arthropathy.Arthralgia involves scope widely and species
It is various, therefore the antidiastole of arthralgia is most important.Arthralgia belongs to the arthrodynia of extremeties, oncotic arthralgia of limbs, numbness in disease of tcm
The illness category such as card, gout.In life, many people are perplexed by arthralgia.The reason for causing arthralgia is a lot, root
According to age, sex, outbreak position, symptom characteristic, soft tissue, cartilage, bone and the original such as struvite can be typically summarized
Cause.At present, treating arthralgic method has the stifling, topical application of drug, drug injection therapy, kinesiatrics and Western medicine etc..Western medicine has bright
Aobvious bad reaction, is treated in prior art using Chinese medicine, but oral result is poor, and large side effects, the course for the treatment of is longer, and curative effect is not
Substantially.
The content of the invention
It is an object of the invention to provide one kind treats arthralgic ache-reliving plaster medicine and its preparation method and application, to solve
The problem proposed in above-mentioned background technology.
For achieving the above object, the present invention provides following technical scheme:
One kind treats arthralgic ache-reliving plaster medicine, is made up of the following raw material according to weight portion:Asiatic striga herb 15-25 parts, ash
Hammer 2-5 parts, scrofula son grass 11-19 parts, Doxycycline Hyclate 1-3 parts, cicada slough 3-7 parts.
As further scheme of the invention:It is described to treat arthralgic ache-reliving plaster medicine, by the following original according to weight portion
Material composition:Asiatic striga herb 18-22 parts, ash hammer 3-4 parts, scrofula son grass 13-17 parts, Doxycycline Hyclate 1.5-2.5 parts, cicada slough 4-6 parts.
As further scheme of the invention:It is described to treat arthralgic ache-reliving plaster medicine, by the following original according to weight portion
Material composition:20 parts of asiatic striga herb, 3.5 parts of ash hammer, 15 parts of scrofula grass, 2 parts of Doxycycline Hyclate, 5 parts of cicada slough.
Another object of the present invention is to provide a kind of preparation method for treating arthralgic ache-reliving plaster medicine, by following steps group
Into:
1) ash hammer, cicada slough are crushed, cross 60 mesh sieves, then with the vinegar immersion 3.5h of the two 0.8 times of quality, and at 65 DEG C
At a temperature of toast 5h, mixed powder A is obtained;
2) it is asiatic striga herb, the sub- grass meal of scrofula is broken, the deionized water of 7.8 times of the two quality is subsequently adding, 3.3h is decocted, filter to take
Filtrate, is then concentrated into the 30% of original volume, adds mixed powder A, stir process 25min at a temperature of 72 DEG C then to lower the temperature
To room temperature, then add Doxycycline Hyclate mixing and stirring and obtain final product ache-reliving plaster medicine.
Another object of the present invention is to provide application of the ache-reliving plaster medicine in treatment arthralgia medicine is prepared.
Another object of the present invention is to provide application of the ache-reliving plaster medicine in treatment omarthralgia medicine is prepared.
There is asiatic striga herb invigorating the spleen to disappear product, the effect of heat-clearing desinsection.It is usually used in invigorating the spleen to disappear product, heat-clearing desinsection.
Ash hammer cures mainly removing heat from the lung and relieving sorethroat;Removing toxicity for detumescence;Hemostasis.Main cough after common cold;Abscess of throat;Sound is mute;Traumatism and bleeding.
Scrofula son grass promoting blood circulation for regulating menstruation, dispersing swelling and dissipating binds.For irregular menstruation;Lymphoid tuberculosis, injury and bone fracture are controlled in external application.
Doxycycline Hyclate be mainly used in sensitivity GPC and gram negative bacilli caused by upper respiratory tract sense
Dye, tonsillitis, infection of biliary tract, lymphnoditis, cellulitis, senile chronic bronchitis etc., are also used for typhus, illness
Parasitosis, Eaton agent pneumonia etc..Still it is used to treat cholera, it can also be used to prevent pernicious malaria and hook Leptospiral infection.
Sound, promoting eruption, removing nebula, Inflammation Zhijing are opened in cicada slough dispelling wind and heat from the body, profit pharynx.For anemopyretic cold, warm disease is from the beginning of pharynx
Pain sound is mute, measles without adequate eruption, rubella itch, cataract, anxious chronic infantile convulsion, and lockjaw card, nocturnal fretfulness in infants is uneasy.
Compared with prior art, the invention has the beneficial effects as follows:
Plaster of the present invention has evident in efficacy, cure rate optimum under the interaction of each raw material for arthralgia is treated
Up to 100%, short treating period has no toxic side effect, non-relapse after healing.And preparation process is simple of the present invention, easy to operate, user
Just, it is suitable to industrialized production.
Specific embodiment
Below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described,
Obviously, described embodiment is only a part of embodiment of the invention, rather than the embodiment of whole.Based in the present invention
Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, all
Belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, one kind treats arthralgic ache-reliving plaster medicine, is made up of the following raw material according to weight portion:Solely
15 parts of pin mandarin orange, 2 parts of ash hammer, 11 parts of scrofula grass, 1 part of Doxycycline Hyclate, 3 parts of cicada slough.
Ash hammer, cicada slough are crushed, cross 60 mesh sieves, then with the vinegar immersion 3.5h of the two 0.8 times of quality, and at 65 DEG C
At a temperature of toast 5h, mixed powder A is obtained.Asiatic striga herb, the sub- grass meal of scrofula is broken, the deionized water of 7.8 times of the two quality is subsequently adding,
3.3h is decocted, filtrate is filtered to take, the 30% of original volume is then concentrated into, mixed powder A, the stir process at a temperature of 72 DEG C is added
25min, is then cooled to room temperature, then adds Doxycycline Hyclate mixing and stirring and obtain final product ache-reliving plaster medicine.
Embodiment 2
In the embodiment of the present invention, one kind treats arthralgic ache-reliving plaster medicine, is made up of the following raw material according to weight portion:Solely
25 parts of pin mandarin orange, 5 parts of ash hammer, 19 parts of scrofula grass, 3 parts of Doxycycline Hyclate, 7 parts of cicada slough.
Ash hammer, cicada slough are crushed, cross 60 mesh sieves, then with the vinegar immersion 3.5h of the two 0.8 times of quality, and at 65 DEG C
At a temperature of toast 5h, mixed powder A is obtained.Asiatic striga herb, the sub- grass meal of scrofula is broken, the deionized water of 7.8 times of the two quality is subsequently adding,
3.3h is decocted, filtrate is filtered to take, the 30% of original volume is then concentrated into, mixed powder A, the stir process at a temperature of 72 DEG C is added
25min, is then cooled to room temperature, then adds Doxycycline Hyclate mixing and stirring and obtain final product ache-reliving plaster medicine.
Embodiment 3
In the embodiment of the present invention, one kind treats arthralgic ache-reliving plaster medicine, is made up of the following raw material according to weight portion:Solely
18 parts of pin mandarin orange, 3 parts of ash hammer, 13 parts of scrofula grass, 1.5 parts of Doxycycline Hyclate, 4 parts of cicada slough.
Ash hammer, cicada slough are crushed, cross 60 mesh sieves, then with the vinegar immersion 3.5h of the two 0.8 times of quality, and at 65 DEG C
At a temperature of toast 5h, mixed powder A is obtained.Asiatic striga herb, the sub- grass meal of scrofula is broken, the deionized water of 7.8 times of the two quality is subsequently adding,
3.3h is decocted, filtrate is filtered to take, the 30% of original volume is then concentrated into, mixed powder A, the stir process at a temperature of 72 DEG C is added
25min, is then cooled to room temperature, then adds Doxycycline Hyclate mixing and stirring and obtain final product ache-reliving plaster medicine.
Embodiment 4
In the embodiment of the present invention, one kind treats arthralgic ache-reliving plaster medicine, is made up of the following raw material according to weight portion:Solely
22 parts of pin mandarin orange, 4 parts of ash hammer, 17 parts of scrofula grass, 2.5 parts of Doxycycline Hyclate, 6 parts of cicada slough.
Ash hammer, cicada slough are crushed, cross 60 mesh sieves, then with the vinegar immersion 3.5h of the two 0.8 times of quality, and at 65 DEG C
At a temperature of toast 5h, mixed powder A is obtained.Asiatic striga herb, the sub- grass meal of scrofula is broken, the deionized water of 7.8 times of the two quality is subsequently adding,
3.3h is decocted, filtrate is filtered to take, the 30% of original volume is then concentrated into, mixed powder A, the stir process at a temperature of 72 DEG C is added
25min, is then cooled to room temperature, then adds Doxycycline Hyclate mixing and stirring and obtain final product ache-reliving plaster medicine.
Embodiment 5
In the embodiment of the present invention, one kind treats arthralgic ache-reliving plaster medicine, is made up of the following raw material according to weight portion:Solely
20 parts of pin mandarin orange, 3.5 parts of ash hammer, 15 parts of scrofula grass, 2 parts of Doxycycline Hyclate, 5 parts of cicada slough.
Ash hammer, cicada slough are crushed, cross 60 mesh sieves, then with the vinegar immersion 3.5h of the two 0.8 times of quality, and at 65 DEG C
At a temperature of toast 5h, mixed powder A is obtained.Asiatic striga herb, the sub- grass meal of scrofula is broken, the deionized water of 7.8 times of the two quality is subsequently adding,
3.3h is decocted, filtrate is filtered to take, the 30% of original volume is then concentrated into, mixed powder A, the stir process at a temperature of 72 DEG C is added
25min, is then cooled to room temperature, then adds Doxycycline Hyclate mixing and stirring and obtain final product ache-reliving plaster medicine.
Comparative example 1
In addition to Doxycycline Hyclate is not contained, remaining formula is consistent with embodiment 5 with preparation process.
Comparative example 2
The direct co-grinding of the raw material of embodiment 5 is obtained into plaster, its formula is consistent with embodiment 5.
Comparative example 3
Only contain Doxycycline Hyclate, its preparation process is consistent with embodiment 5.
Test one, plaster of the present invention has the animal experiment of prefabricated effect to small white mouse painful swelling of joints.
1st, test material:
Animal:Small white mouse 35, male and female half and half, body weight 18g ± 2g is randomly divided into A, B, C, D, E, F, G group, 5 per group.
2nd, experimental condition:
Raise in isolator, between 15-25 DEG C, humidity is between 50-65%, and each 12 hours of light and shade are whole for temperature
Small white mouse freely ingests and drinks water in individual process of the test.
3rd, embodiment:
(1) foundation of acute gout model:Modeling is carried out using classical Coderre modeling methods, is existed respectively with injection needle
The all small white mouse right shoulder joint dorsal parts of B, C, D, E, F, G group from 45 ° of directions insertion shoulder tendons inner side, and by 0.2mL Monosodium urates
Solution (concentration 2.5g100mL-1) inject in shoulder joint chamber, urarthritis model is formed, A groups do not make acute gout model
Process.
(2) A groups:A groups make as a control group, not any process.
(3) B groups:Simply disinfected with alcohol at the pain spot of all small white mouses of B groups.
(4) C groups:The ointment of embodiment 5 is taken out, ointment is coated at the pain spot of B groups small white mouse injection with cotton swab, a coating one
It is secondary, later not in medication.
(5) D groups:The ointment of embodiment 5 is taken out, ointment is put on stickup cream, patch will be pasted at pain spot, treated
Cheng Zhong, is pasted with always ointment.
(6) E groups:The ointment of comparative example 1 is taken out, ointment is put on stickup cream, patch will be pasted at pain spot, treated
Cheng Zhong, is pasted with always ointment.
(7) F groups:The ointment of comparative example 2 is taken out, ointment is put on stickup cream, patch will be pasted at pain spot, treated
Cheng Zhong, is pasted with always ointment.
(8) G groups:The ointment of comparative example 3 is taken out, ointment is put on stickup cream, patch will be pasted at pain spot, treated
Cheng Zhong, is pasted with always ointment.
4th, observation index and evaluation method:Observation index includes small white mouse mental status, the week at the same position of right shoulder joint
Footpath, swelling situation, color, Pi Wen and active situation, and calculate Articular swelling.Articular swelling is calculated:With 3mm width paper slip and
The average week at the same position of the right shoulder joint of 3,6,12,24,36 and 72h every group of small white mouse before vernier caliper measurement experiment and after modeling
Footpath, with modeling front right shoulder joint week footpath difference after calculating modeling.
5th, result
(1) it is observed that control group A group small white mouse is without obvious irritated performance, joint slightly increases slightly compared with before modeling, but base
Keep constant on this, also without obvious red, hot and handicapped performance.
(2) B, C, D, E, F, G group small white mouse is caused after scorching modeling, and the obvious restlessness of small white mouse, right shoulder joint has significantly
Red, swollen, heat, and with dysfunction, limitation of activity, B group small white mouses are the most obvious.After the plaster of the painting present invention, C is still
Comparison is restless, and D groups are a little restless, illustrate that ointment of the present invention has functions that pain relieving.E, F, G group compares after painting ointment respectively
It is more restless, illustrate that comparative example ointment analgesic effect is not obvious.Concrete condition is shown in Table 1-2:
Table 1:Impact (3,6,12 hour) of the plaster of the present invention to small white mouse arthroncus
Table 2:Impact (24,36,72 hour) of the plaster of the present invention to small white mouse arthroncus
From upper two forms, each group small white mouse shoulder joint after inflammation is caused swelling occur, and 6~12h peaks, its
In it is the most obvious with B groups.24~72h after inflammation, two groups of small white mouse shoulder joint swelling degree of C, D is caused to have compared with control group B groups
Different degrees of decline, illustrates that plaster of the present invention has obvious inhibitory action to treating small white mouse shoulder joint swelling, and D groups are little
White mouse shoulder joint swelling degree is significantly lower than C groups, illustrates to be covered with always ointment to treating small white mouse shoulder arthralgia with more bright
Aobvious effect.Although E, F, G group respectively than B group compare and have different degrees of decline after painting comparative example ointment by swelling degree,
It is closer to, particularly G groups, illustrates that the present invention is worked under the collective effect of each component.
Test two, clinical observation on the therapeutic effect test
1st, physical data
Patient 240, it is the oldest 67 years old, minimum 28 years old, 8 groups are randomly divided into, 1 group is respectively treated, 2 groups is treated, is controlled
3 groups are treated, 4 groups is treated, is treated 5 groups, contrast 1 group, contrast 2 groups, 3 groups of contrast, per group of 30 people.There is typical clinical manifestation:Close
Section pain, swelling, activity is restricted, or even basic life all can not take care of oneself.The course of disease is most long 8 years, most short 6 months.
2nd, treatment method
1 group of plaster from above-described embodiment 1 is treated, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
2 groups of plaster from above-described embodiment 2 are treated, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
3 groups of plaster from above-described embodiment 3 are treated, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
4 groups of plaster from above-described embodiment 4 are treated, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
5 groups of plaster from above-described embodiment 5 are treated, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
1 group of plaster from above-mentioned comparative example 1 is contrasted, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
2 groups of plaster from above-mentioned comparative example 2 are contrasted, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
3 groups of plaster from above-mentioned comparative example 3 are contrasted, medical ointment plaster at pain spot, is removed when having a bath, it is after a bath rear former
On ointment repeat sticking, till being labelled to without ointment repeatedly.
3rd, criterion of therapeutical effect:
Cure:Pain disappears, and function of joint is normal;
It is effective:Pain disappears, and function of joint improves;
Effectively:Pain relief, function of joint obtains part improvement;
It is invalid:It is the same with symptom before treatment.
4th, therapeutic effect
Over the course for the treatment of, patient articular's distending pain is decreased obviously, and function of joint is greatly improved, and counts after 5 days
Treatment results, concrete condition refers to table 3.
Table 3:Arthralgia patient's observation of curative effect table
Group | n | Cure | It is effective | Effectively | It is invalid | Cure rate % | Total effective rate % |
Treat 1 group | 30 | 20 | 6 | 3 | 1 | 66.7 | 96.7 |
Treat 2 groups | 30 | 21 | 5 | 4 | 0 | 70 | 100 |
Treat 3 groups | 30 | 26 | 3 | 1 | 0 | 86.7 | 100 |
Treat 4 groups | 30 | 27 | 2 | 1 | 0 | 90 | 100 |
Treat 5 groups | 30 | 30 | 0 | 0 | 0 | 100 | 100 |
Contrast 1 group | 30 | 3 | 9 | 6 | 12 | 10 | 60 |
Contrast 2 groups | 30 | 2 | 8 | 5 | 15 | 6.7 | 50 |
Contrast 3 groups | 30 | 0 | 1 | 4 | 25 | 0 | 16.7 |
As can be seen from the above table, in above-mentioned treatment, after treating 7-20 days, cure rate of the present invention more than 65%;Always have
Efficiency is up to more than 96%;Preferably, cure rate is up to 100% for the plaster curative effect of embodiment 5.In all healing cases, healing in 3 days reaches
60%, the particularly plaster of embodiment 5, the patient of healing 80% of 3 days illustrates that plaster of the invention has to arthralgia good
Therapeutic action, curative effect is fast, and efficient height has no toxic side effect, and security is good.Compared for 5 groups with treatment by contrasting 1-3 groups,
The present invention is functioned as described above under the collective effect of each raw material.
Model case:
Case 1:Korea Spro, man, 40 years old, shoulder arthralgia 3.5 years, activity is restricted, and using this plaster, medical ointment plaster is existed
At pain spot, remove when having a bath, after a bath after on active compound cream repeat sticking, till being labelled to without ointment repeatedly, continuous use is after 2 days,
It was found that pain is significantly reduced, be further continued for medication to after 4 days, shoulder pain disappears, and freedom of movement is almost recovered, then followed by
Continuous medication was discontinued medication to 10 days, and follow-up so far, has no rebound phenomenon.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of spirit or essential attributes without departing substantially from the present invention, the present invention can be in other specific forms realized.Therefore, no matter
From the point of view of which point, embodiment all should be regarded as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit is required rather than described above is limited, it is intended that all in the implication and scope of the equivalency of claim by falling
Change is included in the present invention.
Moreover, it will be appreciated that although this specification is been described by according to embodiment, not each embodiment is only wrapped
Containing an independent technical scheme, this narrating mode of specification is only that for clarity those skilled in the art should
Using specification as an entirety, the technical scheme in each embodiment can also Jing it is appropriately combined, form those skilled in the art
Understandable other embodiment.
Claims (6)
1. one kind treats arthralgic ache-reliving plaster medicine, it is characterised in that be made up of the following raw material according to weight portion:Asiatic striga herb
15-25 parts, ash hammer 2-5 parts, scrofula son grass 11-19 parts, Doxycycline Hyclate 1-3 parts, cicada slough 3-7 parts.
2. it is according to claim 1 to treat arthralgic ache-reliving plaster medicine, it is characterised in that by the following original according to weight portion
Material composition:Asiatic striga herb 18-22 parts, ash hammer 3-4 parts, scrofula son grass 13-17 parts, Doxycycline Hyclate 1.5-2.5 parts, cicada slough 4-6 parts.
3. it is according to claim 1 to treat arthralgic ache-reliving plaster medicine, it is characterised in that by the following original according to weight portion
Material composition:20 parts of asiatic striga herb, 3.5 parts of ash hammer, 15 parts of scrofula grass, 2 parts of Doxycycline Hyclate, 5 parts of cicada slough.
4. a kind of preparation method of the arthralgic ache-reliving plaster medicine for the treatment of as described in claim 1-3 is arbitrary, it is characterised in that by
Following steps are constituted:
1) ash hammer, cicada slough are crushed, cross 60 mesh sieves, then with the vinegar immersion 3.5h of the two 0.8 times of quality, and in 65 DEG C of temperature
The lower baking 5h of degree, is obtained mixed powder A;
2) it is asiatic striga herb, the sub- grass meal of scrofula is broken, the deionized water of 7.8 times of the two quality is subsequently adding, 3.3h is decocted, filter to take filter
Liquid, is then concentrated into the 30% of original volume, adds mixed powder A, stir process 25min at a temperature of 72 DEG C to be then cooled to
Room temperature, then add Doxycycline Hyclate mixing and stirring and obtain final product ache-reliving plaster medicine.
5. application of the ache-reliving plaster medicine as described in claim 1-3 is arbitrary in treatment arthralgia medicine is prepared.
6. application of the ache-reliving plaster medicine as described in claim 1-3 is arbitrary in treatment omarthralgia medicine is prepared.
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Citations (2)
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CN103169821A (en) * | 2011-12-20 | 2013-06-26 | 彭焕庭 | Tendon relaxing and collateral activating plaster and making method thereof |
CN105709003A (en) * | 2016-04-11 | 2016-06-29 | 田永祥 | Black plaster and preparation method thereof |
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2017
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Application publication date: 20170510 |