CN106619763A - Active extractive of pseudo-ginseng flowers or pseudo-ginseng leaves, as well as preparation method, preparations and application thereof - Google Patents

Active extractive of pseudo-ginseng flowers or pseudo-ginseng leaves, as well as preparation method, preparations and application thereof Download PDF

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Publication number
CN106619763A
CN106619763A CN201611189635.6A CN201611189635A CN106619763A CN 106619763 A CN106619763 A CN 106619763A CN 201611189635 A CN201611189635 A CN 201611189635A CN 106619763 A CN106619763 A CN 106619763A
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China
Prior art keywords
pseudo
sanchi
ginseng
leaf
extract
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CN201611189635.6A
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Chinese (zh)
Inventor
戴群
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Individual
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Individual
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Priority to CN201611189635.6A priority Critical patent/CN106619763A/en
Publication of CN106619763A publication Critical patent/CN106619763A/en
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses an active extractive of pseudo-ginseng flowers or pseudo-ginseng leaves, as well as a preparation method, preparations and an application thereof. The active extractive of pseudo-ginseng flowers or pseudo-ginseng leaves is prepared and obtained by taking the pseudo-ginseng flowers or pseudo-ginseng leaves as main materials through the processing steps of pretreatment, extraction, separation and aftertreatment, and the active extractive of pseudo-ginseng flowers or pseudo-ginseng leaves is faint yellow, wherein the relative retention rate of volatile oil components reaches 90% and above. The preparation method comprises the steps of pretreatment, extraction, separation and aftertreatment. The preparations are active extractive pure powder of pseudo-ginseng flowers or pseudo-ginseng leaves or powder, tablets, granules, capsules and pills prepared by adding pharmaceutically acceptable auxiliary materials. The application is application of the active extractive of pseudo-ginseng flowers or pseudo-ginseng leaves in the preparation of medicine, food and health care food capable of clearing heat, protecting liver, stopping bleeding, invigorating the circulation of blood, decreasing blood pressure and blood lipid, easing pain and calming the nerves. The active extractive is rich in completely active raw essence of concentrated pseudo-ginseng, the convenience for storage and carrying is realized, and the active extractive can be efficiently utilized.

Description

Activity extract of a kind of sanchi flower or sanchi leaf and preparation method thereof, preparation with Using
Technical field
The invention belongs to sanchi flower or leaf deep process technology field, and in particular to the activity of a kind of sanchi flower or sanchi leaf is carried Take thing and preparation method thereof, preparation and application.
Background technology
Sanchi flower is the corymb of panax araliaceae plant.Pseudo-ginseng can promote the production of body fluid to quench thirst, tonifying Qi of refreshing oneself, and can make beverage, because Its property is sweet, tool heat-clearing, flat liver, step-down, effect for reducing fat, also pharmaceutically acceptable, cures mainly hypertension, giddy, dizzy, tinnitus.
Sanchi leaf is pseudo-ginseng oblong or Long Circle leaf, taste is pungent, enter liver, the Jing of stomach two, there is hemostasis, detumescence, analgesic efficacy.
Sanchi flower and sanchi leaf have heat-clearing, protect liver, hemostasis promoting blood circulation, hypertension and hyperlipemia, the health maintenance effect of tranquilizing and allaying excitement, and It is medicinal and edible plant.For a long time, people are seldom related to the deep processing research of sanchi flower and sanchi leaf, as pseudo-ginseng is behaved Extensive attention, and the relative shortage of pseudo-ginseng resource, it is necessary to the comprehensive high-efficiency of pseudo-ginseng floral leaf using deeply being opened Send out.Tradition extracts water soluble ingredient using sanchi flower and the sanchi leaf usually directly side's of entering decoction, also someone using traditional handicraft, Make instant tea-drinking.But sanchi flower made by traditional handicraft or pseudo-ginseng leaf instant tea have strand high temperature to extract the lower ointment taste for producing, Mouthfeel is uncomfortable, so it is difficult to as health class product promotion in people's daily life.Inventor Jing concentrates on studies, and develops one Kind of low temperature active novel technology for extracting, make sanchi flower and notoginseng leaf extract remain the natural active component of ecosystem and fragrance into Point, volatile aroma oil component content > raw material volatile aroma oil component content × 90% of its activity extract(That is volatile oil component More than 90% is reached with respect to retention rate).Extract is made after the functional food or health products of people's convenience and high-efficiency very by people's Like, the application of health care life-stylize can be carried out.Therefore, a kind of sanchi flower that can be solved the above problems or sanchi leaf are developed Processing technology be very important.
The content of the invention
The first object of the present invention is the activity extract for providing a kind of sanchi flower or sanchi leaf;Second purpose is to carry For the preparation method of the activity extract of described sanchi flower or sanchi leaf;3rd purpose is to provide described sanchi flower or three The preparation of the activity extract of seven leaves;4th purpose is answering for the activity extract of the described sanchi flower of offer or sanchi leaf With.
The first object of the present invention is achieved in that the activity extract of described sanchi flower or sanchi leaf is with pseudo-ginseng Flower or sanchi leaf are raw material, and premenstrual process, extracting and developing, aftertreatment technology step prepare, described sanchi flower or pseudo-ginseng The activity extract of leaf is faint yellow, and wherein volatile oil component retention rate reaches more than 90%.
The second object of the present invention is achieved in that including pre-treatment, extracting and developing and post-processing step, concrete to wrap Include:
A, pre-treatment:Dry in the shade or low temperature drying after the sanchi flower or sanchi leaf of results are cleaned;
B, extraction:Sanchi flower or sanchi leaf are inserted in cold reflux extractor, the water of 5 ~ 20 times of raw material weight is added, in temperature 15 ~ 75 DEG C of cold refluxs extract 60 ~ 180 min;
C, separation:Extract is separated into material residue, retains water soluble ingredient and lipid, volatile oil component;
D, post processing:Extract is concentrated, is sterilized, is dried to obtain the activity extract of object sanchi flower or sanchi leaf.
Extracting, concentrating, sterilizing and be dried in engineering, be to retain not losing or losing less for volatile oil component, it is impossible to produce The ebuillition of heated phenomenon of raw extract or concentrate.
The third object of the present invention be achieved in that the described pure pulvis of the activity extract of sanchi flower or sanchi leaf or Pharmaceutically acceptable auxiliary material is added to be prepared into powder, tablet, granule, capsule and pill.
The fourth object of the present invention be achieved in that the activity extract of described sanchi flower or sanchi leaf prepare it is clear Application in heat, protect liver, hemostasis promoting blood circulation, hypertension and hyperlipemia, the medicine of analgesic sedative, food and health food.
The present invention is raw material using sanchi flower or sanchi leaf, and the primary elite of enrichment concentration full activity realizes sanchi flower Or storage, the convenience of carrying of sanchi leaf, and can efficient utilization.The activity extraction of sanchi flower of the present invention or sanchi leaf Thing is pale yellow powder, remains the aromatic fragrance of the ecosystem of sanchi flower or sanchi leaf, and remains sanchi flower or sanchi leaf Four natures and five flavors of drug, entrance return it is sweet, it is identical and natural with the mouthfeel that tea-drinking is brewed with the sanchi flower or sanchi leaf of ecosystem The fragrance of ecosystem is more strong.
Specific embodiment
With reference to embodiment, the present invention is further illustrated, but the present invention is any limitation as never in any form, Based on present invention teach that any conversion for being made or replacement, belong to protection scope of the present invention.
The activity extract of sanchi flower of the present invention or sanchi leaf is the premenstrual place with sanchi flower or sanchi leaf as raw material Reason, extracting and developing, aftertreatment technology step are prepared, described sanchi flower or the activity extract of sanchi leaf be it is faint yellow, Wherein volatile oil component retention rate reaches more than 90%.
The preparation method of the activity extract of sanchi flower of the present invention or sanchi leaf, including pre-treatment, extracting and developing And post-processing step, specifically include:
A, pre-treatment:Dry in the shade or low temperature drying after the sanchi flower or sanchi leaf of results are cleaned;
B, extraction:Sanchi flower or sanchi leaf are inserted in cold reflux extractor, the water of 5 ~ 20 times of raw material weight is added, in temperature 15 ~ 75 DEG C of cold refluxs extract 60 ~ 180 min;
C, separation:Extract is separated into material residue, retains water soluble ingredient and lipid, volatile oil component;
D, post processing:Extract is concentrated, is sterilized, is dried to obtain the activity extract of object sanchi flower or sanchi leaf.
Described water is redistilled water or purified water.
Extract does not produce ebuillition of heated phenomenon in whole technical process.I.e. extract occurs without boiling(Including any pressure Can not seethe with excitement under the conditions of power, to ensure the complete and activity of product of the present invention).
The temperature control that step B is extracted carries out cold reflux extraction below 75 DEG C, and it is to be different from hot backflow that cold reflux is extracted A kind of new technology extracted, it is characterized in that extract separates recirculation water is not the method condensed with heating evaporation, but uses normal temperature Membrane Materials, the method for UF membrane separate recirculation water.
It in temperature is less than 40 DEG C cold concentrations that concentration described in D steps is, the temperature control of described sterilizing is at 40 DEG C Hereinafter carry out cold sterilization;Described drying is freeze-drying.
The preparation of the activity extract of sanchi flower of the present invention or sanchi leaf is described sanchi flower or sanchi leaf The pure pulvis of activity extract adds pharmaceutically acceptable auxiliary material to be prepared into powder, tablet, granule, capsule and pill.
The application of the activity extract of sanchi flower of the present invention or sanchi leaf is described sanchi flower or sanchi leaf Activity extract is in heat-clearing, protect liver, hemostasis promoting blood circulation, hypertension and hyperlipemia, the medicine of analgesic sedative, food and health food is prepared Using.
Below to be embodied as case, the present invention will be further described:
Embodiment 1
To dry in the shade or the sanchi flower 20kg of low temperature drying is put in cold reflux extraction element the refluxing extraction 120 at a temperature of 75 DEG C of < Minute, then filter and be centrifugally separating to obtain clarification extract, the concentration of extract Jing low temperature(40 DEG C of <)Afterwards quick-frozen to -20 DEG C with It is lower temporary, then it is freeze-dried after obtain 6.5kg freeze-dried powders, the as pure pulvis of pseudo-ginseng flower extract, by pseudo-ginseng flower extract powder Agent packs the instant tea solid beverage finished product of sanchi flower for 1 gram/bag.
The pure pulvis of 1 bag of sanchi flower activity extract is brewed with 200ml boiling water, it is dissolved in water entirely, and soup look is limpid, entrance is returned It is sweet obvious, there is the distinctive aromatic fragrance of sanchi flower.
Extract is taken into 30g, in being placed in 2L flasks, plus 500ml distilled water, 20ml ether makees extractant, while distilling extraction Take 4 hours, it is extract obtained to have anhydrous Na2SO4Eliminating water, rotary evaporation removes ether, obtains volatile aroma oil component yield and is 0.081%.The volatile aroma oil component yield that acquisition raw material sanchi flower dried flower is extracted with same method is 0.062%, illustrates three Seven flower activity extracts preferably remain the volatile oil fragrance component of former sanchi flower.
Embodiment 2
To dry in the shade or the sanchi leaf 15kg of low temperature drying inserts in cold reflux extraction element the refluxing extraction 160 at a temperature of 50 DEG C of < Minute, then the mesh of Jing 100 filters and is centrifugally separating to obtain clarification extract, the concentration of extract Jing low temperature(40 DEG C of <)It is quick-frozen afterwards Keep in less than -25 DEG C, then it is freeze-dried after obtain 920g sanchi leaf freeze-dried powders, the as pure pulvis of notoginseng leaf extract, will Notoginseng leaf extract pulvis packs the pseudo-ginseng leaf instant tea solid beverage for 1 gram/bag.
The pure pulvis of 1 bag of notoginseng leaf extract is brewed with 200ml boiling water, it is instantly dissolved in water, and soup look is as clear as crystal, and entrance is sweet It is sweet, there is the delicate fragrance of sanchi leaf.
Embodiment 3
The extract 1000g sanchi flowers pulvis of embodiment 1 is mixed with the extract 500g sanchi leaf pulvis of embodiment 2, aluminium foil is used Bag hermetic package is into 1 gram/bag of pseudo-ginseng floral leaf hybrid solid beverage product.

Claims (8)

1. a kind of activity extract of sanchi flower or sanchi leaf, it is characterised in that the activity extraction of described sanchi flower or sanchi leaf Thing is that, with sanchi flower or sanchi leaf as raw material, premenstrual process, extracting and developing, aftertreatment technology step are prepared, described three The activity extract of seven flowers or sanchi leaf is faint yellow, and wherein volatile oil component reaches more than 90% with respect to retention rate.
2. sanchi flower described in a kind of claim 1 or the preparation method of the activity extract of sanchi leaf, it is characterised in that include Pre-treatment, extracting and developing and post-processing step, specifically include:
A, pre-treatment:Dry in the shade or low temperature drying after the sanchi flower or sanchi leaf of results are cleaned;
B, extraction:Sanchi flower or leaf are inserted in cold reflux extractor, the water of 5 ~ 20 times of raw material weight is added, in temperature 15 ~ 75 DEG C cold reflux extracts 60 ~ 180 min;
C, separation:Extract is separated into material residue, retains water soluble ingredient and lipid, volatile oil component;
D, post processing:Extract is concentrated, is sterilized, is dried to obtain the activity extract of object sanchi flower or sanchi leaf.
3. preparation method according to claim 2, it is characterised in that described water is redistilled water or purified water.
4. preparation method according to claim 2, it is characterised in that extract does not produce heating boiling in whole technical process Rise phenomenon.
5. preparation method according to claim 2, it is characterised in that the temperature control that step B is extracted is carried out below 75 DEG C Cold reflux is extracted, and it is a kind of new technology for being different from circumfluence distillation that cold reflux is extracted, and it is characterized in that extract separates recirculation water It is not the method condensed with heating evaporation, but recirculation water is separated with the method for normal temperature Membrane Materials, UF membrane.
6. preparation method according to claim 2, it is characterised in that the concentration described in D steps be temperature be 40 DEG C with Under cold concentration, the temperature control of described sterilizing carries out cold sterilization below 40 DEG C;Described drying is freeze-drying.
7. sanchi flower described in a kind of claim 1 or the preparation of the activity extract of sanchi leaf, it is characterised in that described three The pure pulvis of activity extract of seven flowers or sanchi leaf or add pharmaceutically acceptable auxiliary material be prepared into powder, tablet, granule, Capsule and pill.
8. a kind of application of sanchi flower or the activity extract of sanchi leaf described in claim 1, it is characterised in that described three The activity extract of seven flowers or sanchi leaf is preparing heat-clearing, protect liver, hemostasis promoting blood circulation, hypertension and hyperlipemia, the medicine of analgesic sedative, food With the application in health food.
CN201611189635.6A 2016-12-21 2016-12-21 Active extractive of pseudo-ginseng flowers or pseudo-ginseng leaves, as well as preparation method, preparations and application thereof Pending CN106619763A (en)

Priority Applications (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020087537A1 (en) * 2018-11-02 2020-05-07 王志钢 Panax notoginseng health food, preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105455129A (en) * 2015-12-05 2016-04-06 戴群 Cold chain based natural bionic technology, novel product produced with cold chain based natural bionic technology as well as application

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN105455129A (en) * 2015-12-05 2016-04-06 戴群 Cold chain based natural bionic technology, novel product produced with cold chain based natural bionic technology as well as application

Non-Patent Citations (2)

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Title
吕晴等: "同时蒸馏萃取三七花挥发油成分的气相色谱—质谱分析", 《药物分析杂志》 *
陈东等: "三七叶挥发油的化学成分分析", 《天然产物研究与开发》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020087537A1 (en) * 2018-11-02 2020-05-07 王志钢 Panax notoginseng health food, preparation method and application thereof

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Application publication date: 20170510